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NTNRISPIDLSFLLLERPNRPFHMTAFTIFQKPKGQHSSFGSRLFDAYRHSRAIEPFNYRLSWLGRNVAR WEIVEPDMRNHVQHIVLPGPGSMAQFYETVSFLNTGLLDRGHPLWECYIIDGIEGGRIAIMLKVHHALID GEGGLRAMRGFLSTSPHDKTLAGPWMPAPSARAPRRPQPRVSRRQWLQRGLTGIAKLPSDLVGMVGDAVD LGAQALQLKPQRGALPFAASPTLLNHTAKSAARAYANMELPLAEVKAVAKATDTSINDVVMTIVDDALHH YLDEHRAPADRPLVALMPMSMRSQAGAGNQVSAELIAMGAPKANLRQRLKQVNQATTAAKDKGNGMKSPS RQAYTLSLFASLAMSDVLPGFGKAPSANLVISNMKGPAEQLYLAGAPMVSFGGLPILPPGAGLNVTVASV NEQLCLGIGAAPEAVREPARLAQLIEQAFGQLQADIGRSAPAIAGHQADSA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_2598 | - | - | 100% (472) | hypothetical protein MMAR_2598 |
| M. marinum M | MMAR_3403 | - | 2e-54 | 31.29% (473) | hypothetical protein MMAR_3403 |
| M. marinum M | MMAR_5278 | - | 2e-51 | 32.70% (474) | hypothetical protein MMAR_5278 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3115 | - | 0.0 | 69.18% (464) | hypothetical protein Mb3115 |
| M. gilvum PYR-GCK | Mflv_1058 | - | 2e-40 | 27.18% (471) | hypothetical protein Mflv_1058 |
| M. tuberculosis H37Rv | Rv3088 | - | 0.0 | 69.18% (464) | hypothetical protein Rv3088 |
| M. leprae Br4923 | MLBr_01244 | - | 1e-17 | 22.62% (420) | hypothetical protein MLBr_01244 |
| M. abscessus ATCC 19977 | MAB_4544c | - | 1e-42 | 27.21% (463) | hypothetical protein MAB_4544c |
| M. avium 104 | MAV_0355 | - | 2e-49 | 30.97% (465) | bifunctional wax ester synthase/acyl-coadiacylglycerol |
| M. smegmatis MC2 155 | MSMEG_6322 | - | 2e-52 | 32.76% (464) | bifunctional wax ester synthase/acyl-CoA diacylglycerol |
| M. thermoresistible (build 8) | TH_2030 | - | 7e-49 | 31.10% (463) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_3162 | - | 0.0 | 96.70% (394) | hypothetical protein MUL_3162 |
| M. vanbaalenii PYR-1 | Mvan_2903 | - | 9e-56 | 31.96% (460) | hypothetical protein Mvan_2903 |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_0355|M.avium_104 ----MELIMPTDAV----FLLGESREHPMHVGGLQLYQPPEG-AGRNFVR
MSMEG_6322|M.smegmatis_MC2_155 -MNRMQLMSPTDSM----FLIAESREHPMHVGGLALYDPPDD-AGPEFVR
TH_2030|M.thermoresistible__bu ----MRLISPADSM----FLLAESREHPMHVAGLQLFEPPPGTAGPEFLQ
MAB_4544c|M.abscessus_ATCC_199 ----MPFMPVSDSM----FLIGETREHPFHVGGLQLFKPPVD-AGPDYAE
Mflv_1058|M.gilvum_PYR-GCK MSANSVRLGLQDLM----FIYGETSSSKMHVGGLLPFTPPAD-APRDYLR
MMAR_2598|M.marinum_M --MNTNRISPIDLS----FLLLERPNRPFHMTAFTIFQKPKG-QHSSFGS
MUL_3162|M.ulcerans_Agy99 --------------------------------------------------
Mb3115|M.bovis_AF2122/97 ----MTRINPIDLS----FLLLERANRPNHMAAYTIFEKPKG-QKSSFGP
Rv3088|M.tuberculosis_H37Rv ----MTRINPIDLS----FLLLERANRPNHMAAYTIFEKPKG-QKSSFGP
Mvan_2903|M.vanbaalenii_PYR-1 ---MNAAIPPLDLG----WLLMESPGGTTHVGAMLLFKKPPG--RGSLVR
MLBr_01244|M.leprae_Br4923 MADSVEGIGPFDELGALDYLLHRGEANPRTRAGIMAVELLDT---TPDWN
MAV_0355|M.avium_104 DFYKQLVAQPDFQPTFRKHPAKFVGGIANLGWSYDADVDVDYHVRRSALP
MSMEG_6322|M.smegmatis_MC2_155 ELYEEMVRHTDFQPVFRKHPATLLGGIANVGWTLDDEVDLDYHLRRSALP
TH_2030|M.thermoresistible__bu GLHQRLAAGRELHPTFRKHPATLFGGIAHLGWAVDDDVDFDYHLRRSALP
MAB_4544c|M.abscessus_ATCC_199 VFYEQLMSTTEVSSDFRKRPGQPLAVMGNLTWIVDDEVDWEYHVRRSALP
Mflv_1058|M.gilvum_PYR-GCK GMIDEARRQEVVAPWNRRLAYPRLQFSPLHSWVTDEDFDFDYHVRRSALA
MMAR_2598|M.marinum_M RLFDAYRHSRAIEPFN----YRLSWLGRNVARWEIVEPDMRNHVQHIVLP
MUL_3162|M.ulcerans_Agy99 ---------------------------------------MRNHLQHIVLP
Mb3115|M.bovis_AF2122/97 RLFDAYRHSQAAKPFN----HKLKWLGTDVAAWETVEPDMGYHIRHLALP
Rv3088|M.tuberculosis_H37Rv RLFDAYRHSQAAKPFN----HKLKWLGTDVAAWETVEPDMGYHIRHLALP
Mvan_2903|M.vanbaalenii_PYR-1 EIVEAYRGYRPLPPFN---YVPELLGAGAPHFREAESWDPHYHVQHLSLP
MLBr_01244|M.leprae_Br4923 RFRSRIEDVSQRVLRLRQKVVVPTLPTAAPRWVVDPDFELDFHVRRVRVP
*::: :.
MAV_0355|M.avium_104 SPRRVRELLELTSRWHSSLLDRHRPLWETHIVEGLKDGRFAIYTKVHHAL
MSMEG_6322|M.smegmatis_MC2_155 SPGRPRELLELTSRVHGTLLDRHRPLWEAYLIEGMADGRFAVYTKVHHSL
TH_2030|M.thermoresistible__bu GPGRIRELLDLTSRWHGTLLDRHRPLWEVHLVEGLADGRVAIYFKVHHAL
MAB_4544c|M.abscessus_ATCC_199 RPARVRELLTVTSRWHSSPLDRHRPLWEMHVVEGLSDGRLAVYTKMHHAV
Mflv_1058|M.gilvum_PYR-GCK SPGDERELGVLVSRLHSNHLDLTRPPWELHVIEGLEGGRFALYMKIHHAL
MMAR_2598|M.marinum_M GPGSMAQFYETVSFLNTGLLDRGHPLWECYIIDGIEGGRIAIMLKVHHAL
MUL_3162|M.ulcerans_Agy99 GPGSMAQFYETVSFLNTGLLDRGHPLWECYIIDGIEGGRIAIMLKVHHAL
Mb3115|M.bovis_AF2122/97 APGSMQQFHETVSFLNTGLLDRGHPMWECYIIDGIERGRIAILLKVHHAL
Rv3088|M.tuberculosis_H37Rv APGSMQQFHETVSFLNTGLLDRGHPMWECYIIDGIERGRIAILLKVHHAL
Mvan_2903|M.vanbaalenii_PYR-1 AHSSYEDLLRLVADLHEPMLDRHRPMFRCWLIDGVPGGRFAIYTKTHHSI
MLBr_01244|M.leprae_Br4923 DPGTLREVFDLAEVIQQSPMDVSRPLWTATLVEGLAAGRAAMLLQISHAI
:. . : :* :* : :::*: ** *: : *::
MAV_0355|M.avium_104 IDGVSAQKLMQRALSSD-PDDPEIRAPWTLPKR--SRKAG--PSS-----
MSMEG_6322|M.smegmatis_MC2_155 IDGVSAMKLVERTLSED-PSDTTVRVPWNLPRRESSRRAG--SSS-----
TH_2030|M.thermoresistible__bu IDGVAVMKLMQRTLSTD-PGD-DARVPWNLPPPR-RNPAG--PVS-----
MAB_4544c|M.abscessus_ATCC_199 IDGVGALRMMMRSLSDD-PDARDCQAVWAPAKRRAKSSIV--STTNTSAI
Mflv_1058|M.gilvum_PYR-GCK VDGYSAMRMLGRSLSTD-PASRDTRMFFNVPSPTRSRRDPGAAESSNPLT
MMAR_2598|M.marinum_M IDGEGGLRAMRGFLSTS-PHDKTLAGPWMPAPSARAPRRPQPRVSRRQWL
MUL_3162|M.ulcerans_Agy99 IDGEGGLRAMRGFLSTS-PHDKTLAGPWMPAPSARAPRR--------QWL
Mb3115|M.bovis_AF2122/97 IDGEGGLRAMRNFLSDS-PDDTTLAGPWMSAQGADRPRRTPATVSRRAQL
Rv3088|M.tuberculosis_H37Rv IDGEGGLRAMRNFLSDS-PDDTTLAGPWMSAQGADRPRRTPATVSRRAQL
Mvan_2903|M.vanbaalenii_PYR-1 IDGVSGLRKLYEGLTLS-AEPAIPTPPFAMPHPKSEAAAPTPALR-----
MLBr_01244|M.leprae_Br4923 TDGVGSVEMFAEMYDLERDPPSRPRSPQPIPQDLSRNDLMLQGINHLP--
** . . . . .
MAV_0355|M.avium_104 ------RLSSLVHAAGSVAALAPSTVSLARAALVEQQ--------LTLPF
MSMEG_6322|M.smegmatis_MC2_155 ------LARTATGAATSLAALAPSTIRLARAALLEQQ--------LTLPF
TH_2030|M.thermoresistible__bu ------RLRSATGAVGSVAALAPSTLSLARAALLEQR--------LTLPF
MAB_4544c|M.abscessus_ATCC_199 D-----LVKGAAGAVRQVVSIPPGLLKYGRHALSDPQ--------LVKPL
Mflv_1058|M.gilvum_PYR-GCK A-----TLRALGGVSSAVTGGVSSAVDLTNALVNTQIRRDGENAHIAGSV
MMAR_2598|M.marinum_M QRGLT----GIAKLPSDLVGMVGDAVDLGAQALQLKPQR------GALPF
MUL_3162|M.ulcerans_Agy99 QRGLT----GIAKLPSDLAGMVGDAVDLGAQALQLKPQR------GALPF
Mb3115|M.bovis_AF2122/97 QGQLQGMIKGLTKLPSGLFGVSADAADLGAQALSLKARK------ASLPF
Rv3088|M.tuberculosis_H37Rv QGQLQGMIKGLTKLPSGLFGVSADAADLGAQALSLKARK------ASLPF
Mvan_2903|M.vanbaalenii_PYR-1 -----KLTHAIHTAVTQIGAVNQISLGASRKALSAVLGS---HVEGSLPF
MLBr_01244|M.leprae_Br4923 ----VALAGGVVGGLSGVASVAGRAILRPASTVSGVVGYVRSGIRVLSQA
: . :
MAV_0355|M.avium_104 GAPRTMLN-VKIGGARRCAAQSWPLERIKNVKNAAGVTVNDVVLAMCSGA
MSMEG_6322|M.smegmatis_MC2_155 GAPRTMFN-VKIGGARRVAAQSWPLERLRRIKAVTGATINDIVLAMCAGA
TH_2030|M.thermoresistible__bu GAPRTMFN-VRIGGARRVAAQSWPLQRIRRIRQAAGXTLNDVALAMCAGA
MAB_4544c|M.abscessus_ATCC_199 SAPHTMLN-VSIGGARRFAAQTWSMARIKEAGKALGGTVNDVVLAMCGGA
Mflv_1058|M.gilvum_PYR-GCK SAPHSILN-ARISRNRRFATQQYEFDRLKKLSSQHGATLNDVALAIIGGG
MMAR_2598|M.marinum_M AASPTLLNHTAKSAARAYANMELPLAEVKAVAKATDTSINDVVMTIVDDA
MUL_3162|M.ulcerans_Agy99 AASPTLLNHTAKSAARAYANMELPLAEVKAVAKATDTSINDVVMTIVDDA
Mb3115|M.bovis_AF2122/97 TARRTLFNNTAKSAARAYGNVELPLADVKALAKATGTSVNDVVMTVIDDA
Rv3088|M.tuberculosis_H37Rv TARRTLFNNTAKSAARAYGNVELPLADVKALAKATGTSVNDVVMTVIDDA
Mvan_2903|M.vanbaalenii_PYR-1 VASHAPTN-APPRQARGFATLSLPLQEMHRIGRRHGATLNDLAAAVIDHG
MLBr_01244|M.leprae_Br4923 AEPSPLLR--QRSLATRTEAIEIQLSDLHKAAKAGDGSINDAYLAGLVGA
. . : :: . ::** : .
MAV_0355|M.avium_104 LRYYLLEQNALPDTPLIAMVPVSLRTEEEADAGGNLVGAILCNLATDSDD
MSMEG_6322|M.smegmatis_MC2_155 LRAYLAEQDALPDRPLIAMVPVSMRSEHEADAGGNMVGSILCSLGTDVED
TH_2030|M.thermoresistible__bu LRQYLLEHDALPATPLVAMVPVSLRSADESAGGGNRTGLVLCNLATDSDD
MAB_4544c|M.abscessus_ATCC_199 LRTYLEEQNALPDKPLVAMCPVSIRAEGDQNAG-NSITALLANLATDKPD
Mflv_1058|M.gilvum_PYR-GCK LRKFLSDFDKLPDRSLIAFLPVNVRPKGD-EGGGNAVGAILAPMGTDIED
MMAR_2598|M.marinum_M LHHYLDEHRAPADRPLVALMPMSMR-SQAG--AGNQVSAELIAMGAPKAN
MUL_3162|M.ulcerans_Agy99 LHHYLDEHRAPADGPLVALMPMSMR-SQAG--AGNQVSAELIAMGAPKAN
Mb3115|M.bovis_AF2122/97 LHHYLAEHQASTDRPLVAFMPMSLR-EKSGEGGGNRVSAELVPMGAPKAS
Rv3088|M.tuberculosis_H37Rv LHHYLAEHQASTDRPLVAFMPMSLR-EKSGEGGGNRVSAELVPMGAPKAS
Mvan_2903|M.vanbaalenii_PYR-1 LHSYLREVGQDHPHEFIAMCPVSLR-EDGDSAVGTRVSAIFVRLGKPEAS
MLBr_01244|M.leprae_Br4923 LRRYHEALGVSIS-TLPMAVPVNVRTEADVVGSNRFVGVTLAAP-LGTND
*: : : *:.:* : .
MAV_0355|M.avium_104 PAQRLLTISESMRSNKKVFSQLPRFQALALSAANLSSLALA---AVPGWV
MSMEG_6322|M.smegmatis_MC2_155 PADRLAVIRRSITDNKRVFSELPRLQALALSALLIAPLGLTT--AFPGFV
TH_2030|M.thermoresistible__bu PAERLDRISSSMRSNKRVFSQLPRVQAMALSAAMIAPLGLG---AVPGVV
MAB_4544c|M.abscessus_ATCC_199 PLERFSAIRDSVQAAKSVLSEMTPLQRMLVGALNGAPVLTG---AVPGLV
Mflv_1058|M.gilvum_PYR-GCK PVERLDTITTATRAAKGQLQSMSPAAIIAYSAALLAPAGSQIAGALTGVQ
MMAR_2598|M.marinum_M LRQRLKQVNQATTAAKDKGNGMKSPSRQAYTLSLFASLAMSD--VLPGFG
MUL_3162|M.ulcerans_Agy99 LRQRLKQVSQATTAAKDKGDGMKSPSRQAYTLSLFASLAMSD--VLPGFG
Mb3115|M.bovis_AF2122/97 PVERLKEINAATTRAKDKGRGMQTTSRQAYALLLLGSLTVAD--ALPLLG
Rv3088|M.tuberculosis_H37Rv PVERLKEINAATTRAKDKGRGMQTTSRQAYALLLLGSLTVAD--ALPLLG
Mvan_2903|M.vanbaalenii_PYR-1 MVDRLRQVARSVAIAKEELGALSADAAMTYAVALVALAGAG---ASTHLD
MLBr_01244|M.leprae_Br4923 PAARMQKIRSQMTQRRDE----PAMNIIGSLAPLMTVLPAS----VLDFI
*: : :
MAV_0355|M.avium_104 SATSPPFNIVISNVPGPTAPLYYGGARLDGNYPLSIVLDGQALNITLASN
MSMEG_6322|M.smegmatis_MC2_155 DATAPPFNLVISNVPGPKKPLYWRGARLAGNYPLSIALDGQALNMTVVSN
TH_2030|M.thermoresistible__bu SSAPPPFNLVISNVPGAPEPRYWMGARLAGNYPLSIVLDGQALNITLVTN
MAB_4544c|M.abscessus_ATCC_199 DRTAPAFNVIISNVPGPRTDMFWNGFEMDGCYPASIPIDGVALNITCTSS
Mflv_1058|M.gilvum_PYR-GCK PPWPYTFNLCVSNVPGPREPLYFNGSRLEATYPVSIPIHGMALNITLQSY
MMAR_2598|M.marinum_M --KAPSANLVISNMKGPAEQLYLAGAPMVSFGGLPILPPGAGLNVTVASV
MUL_3162|M.ulcerans_Agy99 --KAPSANLVISNMKGPAEQLYLAGAPMVSFGGLPILPPGAGLNVTVASV
Mb3115|M.bovis_AF2122/97 --KLPSANVVISNMKGPTEQLYLAGAPLVAFSGLPIVPPGAGLNVTFASI
Rv3088|M.tuberculosis_H37Rv --KLPSANVVISNMKGPTEQLYLAGAPLVAFSGLPIVPPGAGLNVTFASI
Mvan_2903|M.vanbaalenii_PYR-1 RVGHPACNLVISNIPGGNATRYLNGAQLMGIFPVSALAASIGLNVTLTSY
MLBr_01244|M.leprae_Br4923 VDSVASSDVNASNIPAYPGDTYFAGAKILRQYGIGPRP-GVAMMAVLMSR
. :: **: . : * : . .: . :
MAV_0355|M.avium_104 AGNLDFGLVGCRRSVPHLQRLLMHLESSLKDLERAVGE------------
MSMEG_6322|M.smegmatis_MC2_155 AHNLDFGLVGCRRSVPHLQRLLGHLETSLKDLETATGA------------
TH_2030|M.thermoresistible__bu ADNLDFGLVGARGSVPHLQRLLGHLEDSLQQLERAVGG------------
MAB_4544c|M.abscessus_ATCC_199 GSSMHFGLTGCRTSVPHLQRILAHLEDALTQLEESVA-------------
Mflv_1058|M.gilvum_PYR-GCK ADTMNLGFVGCRDRLPHLQRLAVYTGDALAELEAASQI------------
MMAR_2598|M.marinum_M NEQLCLGIGAAPEAVREPARLAQLIEQAFGQLQADIGRSAPAIAGHQADS
MUL_3162|M.ulcerans_Agy99 NEQLCLGIGAAPEAVREPARLAQLIEQAFGQLQADIGRSAPAIAGHQADS
Mb3115|M.bovis_AF2122/97 NTALCIAIGAAPEAVHEPSRLAELMQRAFTELQTEAGTTSPTTSKSRTP-
Rv3088|M.tuberculosis_H37Rv NTALCIAIGAAPEAVHEPSRLAELMQRAFTELQTEAGTTSPTTSKSRTP-
Mvan_2903|M.vanbaalenii_PYR-1 CDHMDFGFVANTAAISDVHALAEHTRRAFAECTAKTRVT-----------
MLBr_01244|M.leprae_Br4923 GGFCTVTVRYDRASVKSEALFARCLLEGFDEVLALAGDPTPHAVPASFAA
. . : : .: :
MAV_0355|M.avium_104 -------------
MSMEG_6322|M.smegmatis_MC2_155 -------------
TH_2030|M.thermoresistible__bu -------------
MAB_4544c|M.abscessus_ATCC_199 -------------
Mflv_1058|M.gilvum_PYR-GCK -------------
MMAR_2598|M.marinum_M A------------
MUL_3162|M.ulcerans_Agy99 A------------
Mb3115|M.bovis_AF2122/97 -------------
Rv3088|M.tuberculosis_H37Rv -------------
Mvan_2903|M.vanbaalenii_PYR-1 -------------
MLBr_01244|M.leprae_Br4923 RSSGSPAGWLSSS