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MADSVEGIGPFDELGALDYLLHRGEANPRTRAGIMAVELLDTTPDWNRFRSRIEDVSQRVLRLRQKVVVP TLPTAAPRWVVDPDFELDFHVRRVRVPDPGTLREVFDLAEVIQQSPMDVSRPLWTATLVEGLAAGRAAML LQISHAITDGVGSVEMFAEMYDLERDPPSRPRSPQPIPQDLSRNDLMLQGINHLPVALAGGVVGGLSGVA SVAGRAILRPASTVSGVVGYVRSGIRVLSQAAEPSPLLRQRSLATRTEAIEIQLSDLHKAAKAGDGSIND AYLAGLVGALRRYHEALGVSISTLPMAVPVNVRTEADVVGSNRFVGVTLAAPLGTNDPAARMQKIRSQMT QRRDEPAMNIIGSLAPLMTVLPASVLDFIVDSVASSDVNASNIPAYPGDTYFAGAKILRQYGIGPRPGVA MMAVLMSRGGFCTVTVRYDRASVKSEALFARCLLEGFDEVLALAGDPTPHAVPASFAARSSGSPAGWLSS S
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. leprae Br4923 | MLBr_01244 | - | - | 100% (491) | hypothetical protein MLBr_01244 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2509c | - | 0.0 | 74.54% (491) | hypothetical protein Mb2509c |
| M. gilvum PYR-GCK | Mflv_2563 | - | 1e-180 | 61.55% (476) | hypothetical protein Mflv_2563 |
| M. tuberculosis H37Rv | Rv2484c | - | 0.0 | 74.34% (491) | hypothetical protein Rv2484c |
| M. abscessus ATCC 19977 | MAB_3551c | - | 1e-27 | 24.84% (455) | hypothetical protein MAB_3551c |
| M. marinum M | MMAR_3835 | - | 0.0 | 74.07% (486) | hypothetical protein MMAR_3835 |
| M. avium 104 | MAV_1686 | - | 0.0 | 75.82% (488) | acyltransferase, ws/dgat/mgat subfamily protein |
| M. smegmatis MC2 155 | MSMEG_4705 | - | 1e-176 | 64.73% (465) | acyltransferase, ws/dgat/mgat subfamily protein |
| M. thermoresistible (build 8) | TH_1039 | - | 1e-172 | 62.92% (472) | acyltransferase, ws/dgat/mgat subfamily protein |
| M. ulcerans Agy99 | MUL_3765 | - | 0.0 | 72.36% (492) | hypothetical protein MUL_3765 |
| M. vanbaalenii PYR-1 | Mvan_4076 | - | 1e-177 | 62.26% (477) | hypothetical protein Mvan_4076 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2563|M.gilvum_PYR-GCK --MSNSSGLDAAGLPEELSPLDQILHRGE--ANPRTRSGIMTIELLDTTP
Mvan_4076|M.vanbaalenii_PYR-1 --MSNEPELDAAGLPEELSPLDQILHRGE--GNPRTRSGIMTLELLDTTP
TH_1039|M.thermoresistible__bu --MSDVPELDAAGLPEELSGLDQILHRGE--ANPRTRSGIMAVELLDTTP
MSMEG_4705|M.smegmatis_MC2_155 --MSYVPERDAAGLPEELSAVDQLLHRGE--ANPRTRSGIMGVELLDTTP
Mb2509c|M.bovis_AF2122/97 ----MAESGESPRLSDELGPVDYLMHRGE--ANPRTRSGIMALELLDGTP
Rv2484c|M.tuberculosis_H37Rv ----MAESGESPRLSDELGPVDYLMHRGE--ANPRTRSGIMALELLDGTP
MMAR_3835|M.marinum_M -------MAEAVGLSDELGPVDYLMHRGE--ANPRTRSGIMALELLDTTP
MUL_3765|M.ulcerans_Agy99 MAEWVVIMAEAVGLSDELGPVDYLMHRGE--ANPRTCSGIMALELLDTTP
MAV_1686|M.avium_104 --MTMTESVETIKLSDELGPVDYLMHRGE--ANPRTRSGIMALELLDTTP
MLBr_01244|M.leprae_Br4923 ----MADSVEGIGPFDELGALDYLLHRGE--ANPRTRAGIMAVELLDTTP
MAB_3551c|M.abscessus_ATCC_199 ------MGKAARIVVSRLSALDASFYSSEDSATPMHVGSLAIIRRPRGGF
..*. :* :: .* ..* ..: :.
Mflv_2563|M.gilvum_PYR-GCK DWDTFRTRFEHASRKVLRLRQKVVTPTLPTTAPRWVVDPDFNLDFHLRRV
Mvan_4076|M.vanbaalenii_PYR-1 DWDTFRTRFDNASRKVLRLRQKVVTPTLPTAAPRWVVDPDFNLDFHVRRV
TH_1039|M.thermoresistible__bu DWDRFRTRFDHASRRVLRLRQKVVMPTLPTAPARWVVDPDFNLDYHVRRV
MSMEG_4705|M.smegmatis_MC2_155 DWERFRTRFDHASRKVVRLRQKVVMPTLPTAAPRWVVDPDFNLDYHVRRV
Mb2509c|M.bovis_AF2122/97 DWDRFRTRFENASRRVLRLRQKVVVPTLPTAAPRWVVDPDFNLDFHVRRV
Rv2484c|M.tuberculosis_H37Rv DWDRFRTRFENASRRVLRLRQKVVVPTLPTAAPRWVVDPDFNLDFHVRRV
MMAR_3835|M.marinum_M DWERFRTRFENASRRVLRLRQKVVVPTLPTAAPRWVVDPDFNLDFHVRRV
MUL_3765|M.ulcerans_Agy99 DWERFRTRFENASRRVLRLRQKVVVPTLPTAAPRWVVDPDFNLDFHVRRV
MAV_1686|M.avium_104 DWQQFRARFENASRRVLRLRQKVVVPTLPTAAPRWVIDPDFNLDFHVRRV
MLBr_01244|M.leprae_Br4923 DWNRFRSRIEDVSQRVLRLRQKVVVPTLPTAAPRWVVDPDFELDFHVRRV
MAB_3551c|M.abscessus_ATCC_199 TYEELLALVESRLPQVPRYRQKVKEIGFGLARPVWLDDVDFDITYHIRRS
:: : : .: :* * **** : : . *: * **:: :*:**
Mflv_2563|M.gilvum_PYR-GCK RVPEPGTLRQVMDFAEIAAQSPLDISRPLWTATLIEGVQDGRAALMVHLS
Mvan_4076|M.vanbaalenii_PYR-1 RVPQPGTFRQVMDLAEIAAQSPLDISRPLWTATLIEGVENGRAALMVHLS
TH_1039|M.thermoresistible__bu RVPEPGTLRQVFDLAEVDMQSPLDISRPLWTATLVEGLRDGRAATMLHLS
MSMEG_4705|M.smegmatis_MC2_155 RVPGPGTLRQVLDLAEVAMQSPMDITRPLWSATLVEGLADGRAATILHLS
Mb2509c|M.bovis_AF2122/97 RVSGPATLREVLDLAEVILQSPLDISRPLWTATLVEGMADGRAAMLLHVS
Rv2484c|M.tuberculosis_H37Rv RVSGPATLREVLDLAEVILQSPLDISRPLWTATLVEGMADGRAAMLLHVS
MMAR_3835|M.marinum_M RVSEPGTLRDVFDLAEVILQSPLDISRPLWTATLVEGLADGKAATLLHVS
MUL_3765|M.ulcerans_Agy99 RVSEPGTLRDVFDLAEVILQSPLDISRPLWTATLVEGLADGKAATLLHVS
MAV_1686|M.avium_104 RVAEPGTLREVFDLAELILQSPMDISRPLWTATLVDGLADGKAATLLHVS
MLBr_01244|M.leprae_Br4923 RVPDPGTLREVFDLAEVIQQSPMDVSRPLWTATLVEGLAAGRAAMLLQIS
MAB_3551c|M.abscessus_ATCC_199 ALPSPGSDGQLQDLVARLTSRPLDRSRPLWEMYLVEGLSKNRLAIYTKTH
:. *.: :: *:. . *:* :**** *::*: .: * :
Mflv_2563|M.gilvum_PYR-GCK HAVTDGVGGVEMFANLYDFEREPPPQPVPPMPVPTDLSPNDLMRSGLNRL
Mvan_4076|M.vanbaalenii_PYR-1 HAVTDGVGGVEMFANLYDFERDPPPQSTPPLPIPSDLSPNDLMRAGLNRL
TH_1039|M.thermoresistible__bu HAVTDGVGGVEMFASIYDFERDPPPGKEPPLPIPQDLTPNDLMWEGVGRL
MSMEG_4705|M.smegmatis_MC2_155 HAVSDAVGGVEMFASIYDLERDPEPDTPPPLPIPQDLSPGELMREGINRL
Mb2509c|M.bovis_AF2122/97 HAVTDGVGGVEMFAQIYDLERDPPPRSTPPQPIPEDLSPNDLMRRGINHL
Rv2484c|M.tuberculosis_H37Rv HAVTDGVGGVEMFAQIYDLERDPPPRSTPPQPIPEDLSPNDLMRRGINHL
MMAR_3835|M.marinum_M HAVTDGVGGVEMFAQIYDLERDPAPRPTPPLPIPQDLSPNDLMREGIGHL
MUL_3765|M.ulcerans_Agy99 HAVTDGVGGVEMFAQIYNLERDPAPRPTPPLPIPQDLSPNDLMREGIGHL
MAV_1686|M.avium_104 HAVTDGVGGVQMFAEIYDLERNPPPKPPPPLPVPQDLSPNDLMRQGINHL
MLBr_01244|M.leprae_Br4923 HAITDGVGSVEMFAEMYDLERDPPSRPRSPQPIPQDLSRNDLMLQGINHL
MAB_3551c|M.abscessus_ATCC_199 QALVDGNSALSLGQVIFDRTAR-TPDFGEDIWVPEHEPSTSELVAGAVSE
:*: *. ..:.: ::: . :* . . . : *
Mflv_2563|M.gilvum_PYR-GCK PGTIVGGVVGAVAGAAQAVGHVVRDPVERLGSVFDYARSGVRVVGPVADP
Mvan_4076|M.vanbaalenii_PYR-1 PGTIVGGVRDALFGAAQAVGHVVRDPVSRLGSAFDYAMSGLRVVGPVADP
TH_1039|M.thermoresistible__bu PRSVVRGVRGLLGDTVRAVGKTLRDPRATVEGVLDYAASSARLVTPVAEP
MSMEG_4705|M.smegmatis_MC2_155 PGSIAGGVLGALGGAARAVTKVVRDPISAVSGVVDYAMSGTRVMAPAAEP
Mb2509c|M.bovis_AF2122/97 PIAVVGGVLDALSGAVSMAGRAVLEPVSTVSGILGYARSGIRVLNRAAEP
Rv2484c|M.tuberculosis_H37Rv PIAVVGGVLDALSGAVSMAGRAVLEPVSTVSGILGYARSGIRVLNRAAEP
MMAR_3835|M.marinum_M PIALVGGVAGAIAGAVSVAGRAVLDPAATVSGIVGYALSSVRVMNRAAEP
MUL_3765|M.ulcerans_Agy99 PIALVGGVAGAIAGAVSVAGRAVLDSAATVSGIVGYALSSVRVMNRAAEP
MAV_1686|M.avium_104 PFAVVGGVVSALSGAVSVAGRAMLEPASTVSGIVGYAMSGMRVLNRAAEP
MLBr_01244|M.leprae_Br4923 PVALAGGVVGGLSGVASVAGRAILRPASTVSGVVGYVRSGIRVLSQAAEP
MAB_3551c|M.abscessus_ATCC_199 WLARPGARLEAVRNTVADVASLTGEIGELGERMVKVVRTAARGAAPRG--
: . : ... . . . :. * .
Mflv_2563|M.gilvum_PYR-GCK SPILRRRSLSSRSEAIDIEFSDLHRASKAAEGSINDAYLAGLCGALRLYH
Mvan_4076|M.vanbaalenii_PYR-1 SPILRRRSLSSRSDAIDIEFGDLHRAAKAAGGSINDAYLAGLCGALRLYH
TH_1039|M.thermoresistible__bu SPILRRRSLASRTGAIDIRFEDLRKAAKAGGGSINDAYLTGLCGALRLYH
MSMEG_4705|M.smegmatis_MC2_155 SPLLRRRSLASRSEAIDIPFGDFHRAAKAAGGSINDAYLAGVCGALRLYH
Mb2509c|M.bovis_AF2122/97 SPLLRRRSLTTRTEAIDIRLADLHKAAKAGGGSINDAYLAGLCGALRRYH
Rv2484c|M.tuberculosis_H37Rv SPLLRRRSLTTRTEAIDIRLADLHKAAKAGGGSINDAYLAGLCGALRRYH
MMAR_3835|M.marinum_M SPLLRRRSLTTRTEAIDIRLSELHKAAKAGGGSINDAYLAGLCGALRRYH
MUL_3765|M.ulcerans_Agy99 SPLLRRRSLTTRTEAIDIRLSELHKAAKAGGGSINDAYLAGLCGALRRYH
MAV_1686|M.avium_104 SPLLRRRSLATRSEAIDIPLADLHKAAKAGGGSINDAYLAGLCGALRRYH
MLBr_01244|M.leprae_Br4923 SPLLRQRSLATRTEAIEIQLSDLHKAAKAGDGSINDAYLAGLVGALRRYH
MAB_3551c|M.abscessus_ATCC_199 -PLNQRVSRSRRFGVVSTKLADYRRVRAKYDCDVNDVVLATIAGALRNWL
*: :: * : * .:. : : ::. .:**. *: : **** :
Mflv_2563|M.gilvum_PYR-GCK ESMGVPVD---TLPMAVPVNLRSDADPAGGNRFVGVN------LAAPVGL
Mvan_4076|M.vanbaalenii_PYR-1 EAKGVPID---TLPMAVPVNLRSEADPAGGNRFVGVN------LAAPIGV
TH_1039|M.thermoresistible__bu DALGVPVD---TLPMAVPVNLRSDADPAGGNRFTGVN------LAAPIGI
MSMEG_4705|M.smegmatis_MC2_155 DAKGVPID---SLPMAVPVNLRAEDDPAGGNRFAGVN------LSAPIGI
Mb2509c|M.bovis_AF2122/97 EALGVPIS---TLPMAVPVNLRAEGDAAGGNQFTGVN------LAAPVGT
Rv2484c|M.tuberculosis_H37Rv EALGVPIS---TLPMAVPVNLRAEGDAAGGNQFTGVN------LAAPVGT
MMAR_3835|M.marinum_M EALGMPIS---TLPMAVPVNLRADADGAGGNRFTGVN------LAAPVGT
MUL_3765|M.ulcerans_Agy99 EALGMPIS---TLPMAVPVNLRADADGAGGNRFTGVNRFTGVNLAAPVGT
MAV_1686|M.avium_104 EAFGVPIS---TLPMAVPVNLRAEADTAGGNRFTGVN------LAAPIGT
MLBr_01244|M.leprae_Br4923 EALGVSIS---TLPMAVPVNVRTEADVVGSNRFVGVT------LAAPLGT
MAB_3551c|M.abscessus_ATCC_199 MSRGEPVTTASTIRAMVPMSVYRDGDLDVGGEGAATTEVSPFLVDLPVGE
: * .: :: **:.: : * ... .... : *:*
Mflv_2563|M.gilvum_PYR-GCK SDPAMRIKEIRAQMRSKRDERALDVVGAIAPLVSLLP---DSVLETMAGS
Mvan_4076|M.vanbaalenii_PYR-1 SDPEVRIQDIRSQMTRKRDERAMDMVGAIAPVVSLLP---DTVLESMAGS
TH_1039|M.thermoresistible__bu VDPVDRMQDVRAQMTRKREERALDLLGMVAPVGSLLP---DTVLEALAGT
MSMEG_4705|M.smegmatis_MC2_155 EDAEQRIKSVRSQMTSLREERAIDVVGAIAPVLSLLP---DTILESVAGS
Mb2509c|M.bovis_AF2122/97 IDPVARMKKIRAQMTQRRDEPAMNIIGSIAPVLSVLP---TAVLEGITGS
Rv2484c|M.tuberculosis_H37Rv IDPVARMKKIRAQMTQRRDEPAMNIIGSIAPVLSVLP---TAVLEGITGS
MMAR_3835|M.marinum_M ADPVARMKKIRAQMTQRRDEPAMNVVGSMAPVLSVLP---TAVLEGISSS
MUL_3765|M.ulcerans_Agy99 ADPVARMKKIRAQMTQRRDEPAMNVVGSMAPVLSVLP---TAVLEGISSS
MAV_1686|M.avium_104 VDPVSRMKKIRAQMTQRRDEPAMNIIGSLAPVLSVLP---TAVLEGITGS
MLBr_01244|M.leprae_Br4923 NDPAARMQKIRSQMTQRRDEPAMNIIGSLAPLMTVLP---ASVLDFIVDS
MAB_3551c|M.abscessus_ATCC_199 GNTVVRLSQIAHATESHSAAFSLVDVPNMAALSGFVPPTLHALAARVAST
:. *:..: :: : :*.: .:* :: : .:
Mflv_2563|M.gilvum_PYR-GCK IVN--SDVQASNVPVYAGDTFIAGAKVLRQYGLGPLP-GVAMMVVLISRS
Mvan_4076|M.vanbaalenii_PYR-1 FVN--SDVQASNVPVYAGDTFIAGAKVLRQYGLGPLP-GVAMMVVLISRS
TH_1039|M.thermoresistible__bu VVN--SDVQASNVPVILEDTYIAGAKVLRQYGLGPLP-GVAMMVVLVSRS
MSMEG_4705|M.smegmatis_MC2_155 VVN--SDVQASNVPIYPGDTFLAGAKILRHYGLGPLP-GVAMMVVLISRG
Mb2509c|M.bovis_AF2122/97 VIG--SDVQASNVPVYPGDTYLAGAKILRQYGIGPLP-GVAMMVVLISRG
Rv2484c|M.tuberculosis_H37Rv VIG--SDVQASNVPVYPGDTYLAGAKILRQYGIGPLP-GVAMMVVLISRG
MMAR_3835|M.marinum_M VIG--SDVQASNVPVYPGDTFVAGAKILRQYGIGPLP-GVAMMVVLISRG
MUL_3765|M.ulcerans_Agy99 VIG--SDVQASNVPVYPGDTFVAGAKILRQYGIGPLP-GVAMMVVLISRG
MAV_1686|M.avium_104 VIG--SDVQASNVPVFPGDTYIAGAKVLRQYGIGPLP-GVAMMVVLISRG
MLBr_01244|M.leprae_Br4923 VAS--SDVNASNIPAYPGDTYFAGAKILRQYGIGPRP-GVAMMAVLMSRG
MAB_3551c|M.abscessus_ATCC_199 LPNRLFNLLVTNVPGPQAPMYLGGARLAEIYPVPPLLRNQVLSIGLTSYN
. . :: .:*:* :..**:: . * : * . .: * * .
Mflv_2563|M.gilvum_PYR-GCK GYCTISTRYDRASITDPGLLAQCLLDGFDEVLALGGD--GRAVPATFSRV
Mvan_4076|M.vanbaalenii_PYR-1 GYCTVTARYDRAAITDPDLLAQCLLAGFDEVLALGGD--GRAVPATFTAQ
TH_1039|M.thermoresistible__bu GYFTVTARYDRAAITDARLFAHCLLAGFNEVLALGGD--GRAEPASFEVD
MSMEG_4705|M.smegmatis_MC2_155 GYITVTVRYDRAAITDGALFARCLQQGFDEVLALGGE--VRCTPASFDPE
Mb2509c|M.bovis_AF2122/97 GWCTVTVRYDRASVRNDELFAQCLQAGFDEILALAGDPAPRVLPASFDTQ
Rv2484c|M.tuberculosis_H37Rv GWCTVTVRYDRASVRNDELFAQCLQAGFDEILALAGGPAPRVLPASFDTQ
MMAR_3835|M.marinum_M GWATITVRYDRASVRHDELFARCLVEGFDEILALAGDPAPRSIPASFTTV
MUL_3765|M.ulcerans_Agy99 GWATITVRYDRASVRHDELFARCLVEGFDEILVLAGDPAPRSIPASFTTV
MAV_1686|M.avium_104 GWCTITVRYDRASVRDEALFAQCLLEGFDEILALAGDGAPRAVPASFTES
MLBr_01244|M.leprae_Br4923 GFCTVTVRYDRASVKSEALFARCLLEGFDEVLALAGDPTPHAVPASFAAR
MAB_3551c|M.abscessus_ATCC_199 GTVYYGINADREAMPDADMLPLLITEALDELLEAAQ--------------
* . ** :: ::. : .::*:* .
Mflv_2563|M.gilvum_PYR-GCK GAQEK---------------
Mvan_4076|M.vanbaalenii_PYR-1 TTPPVDSARLNGSGPQ----
TH_1039|M.thermoresistible__bu PARLEALMSNAVVPSESAMR
MSMEG_4705|M.smegmatis_MC2_155 PGTNIGGAQ-----------
Mb2509c|M.bovis_AF2122/97 GAGSVPRSVSGS--------
Rv2484c|M.tuberculosis_H37Rv GAGSVPRSVSGS--------
MMAR_3835|M.marinum_M -SGSESRSVSNS--------
MUL_3765|M.ulcerans_Agy99 -SGSESRSVSNS--------
MAV_1686|M.avium_104 --AVSARSASGS--------
MLBr_01244|M.leprae_Br4923 SSGSPAGWLSSS--------
MAB_3551c|M.abscessus_ATCC_199 --------------------