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PFMPVSDSMFLIGETREHPFHVGGLQLFKPPVDAGPDYAEVFYEQLMSTTEVSSDFRKRPGQPLAVMGNL TWIVDDEVDWEYHVRRSALPRPARVRELLTVTSRWHSSPLDRHRPLWEMHVVEGLSDGRLAVYTKMHHAV IDGVGALRMMMRSLSDDPDARDCQAVWAPAKRRAKSSIVSTTNTSAIDLVKGAAGAVRQVVSIPPGLLKY GRHALSDPQLVKPLSAPHTMLNVSIGGARRFAAQTWSMARIKEAGKALGGTVNDVVLAMCGGALRTYLEE QNALPDKPLVAMCPVSIRAEGDQNAGNSITALLANLATDKPDPLERFSAIRDSVQAAKSVLSEMTPLQRM LVGALNGAPVLTGAVPGLVDRTAPAFNVIISNVPGPRTDMFWNGFEMDGCYPASIPIDGVALNITCTSSG SSMHFGLTGCRTSVPHLQRILAHLEDALTQLEESVA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4544c | - | - | 100% (457) | hypothetical protein MAB_4544c |
| M. abscessus ATCC 19977 | MAB_0507 | - | 2e-56 | 32.49% (477) | hypothetical protein MAB_0507 |
| M. abscessus ATCC 19977 | MAB_1917 | - | 1e-51 | 30.37% (461) | hypothetical protein MAB_1917 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3761c | - | 1e-129 | 51.31% (458) | hypothetical protein Mb3761c |
| M. gilvum PYR-GCK | Mflv_1058 | - | 3e-91 | 40.48% (462) | hypothetical protein Mflv_1058 |
| M. tuberculosis H37Rv | Rv3734c | - | 1e-129 | 51.31% (458) | hypothetical protein Rv3734c |
| M. leprae Br4923 | MLBr_01244 | - | 1e-27 | 25.61% (410) | hypothetical protein MLBr_01244 |
| M. marinum M | MMAR_5271 | - | 1e-124 | 50.00% (458) | hypothetical protein MMAR_5271 |
| M. avium 104 | MAV_0355 | - | 1e-132 | 52.08% (457) | bifunctional wax ester synthase/acyl-coadiacylglycerol |
| M. smegmatis MC2 155 | MSMEG_6322 | - | 1e-129 | 49.67% (455) | bifunctional wax ester synthase/acyl-CoA diacylglycerol |
| M. thermoresistible (build 8) | TH_2030 | - | 1e-123 | 49.67% (459) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_4351 | - | 1e-122 | 49.89% (449) | hypothetical protein MUL_4351 |
| M. vanbaalenii PYR-1 | Mvan_5773 | - | 1e-88 | 39.52% (458) | hypothetical protein Mvan_5773 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1058|M.gilvum_PYR-GCK MSANSVRLGLQDLM----FIYGETSSSKMHVGGLLPFTPP-ADAPRDYLR
Mvan_5773|M.vanbaalenii_PYR-1 -------------M----FIYGETSSSKMHVAGLLPFTPP-ADAPRDYLR
MSMEG_6322|M.smegmatis_MC2_155 -MNRMQLMSPTDSM----FLIAESREHPMHVGGLALYDPP-DDAGPEFVR
TH_2030|M.thermoresistible__bu ----MRLISPADSM----FLLAESREHPMHVAGLQLFEPPPGTAGPEFLQ
Mb3761c|M.bovis_AF2122/97 ----MDLMMPNDSM----FLFIESREHPMHVGGLSLFEPP-QGAGPEFVR
Rv3734c|M.tuberculosis_H37Rv ----MDLMMPNDSM----FLFIESREHPMHVGGLSLFEPP-QGAGPEFVR
MMAR_5271|M.marinum_M ----MELMMPTDSM----FLFVESREHPMHVGGLSLFEPP-EGAGPDFVR
MAV_0355|M.avium_104 ----MELIMPTDAV----FLLGESREHPMHVGGLQLYQPP-EGAGRNFVR
MUL_4351|M.ulcerans_Agy99 -------MSPVDAL----FLSAESREHPLHVGALQLFEPP-EGAGRAFVH
MAB_4544c|M.abscessus_ATCC_199 ----MPFMPVSDSM----FLIGETREHPFHVGGLQLFKPP-VDAGPDYAE
MLBr_01244|M.leprae_Br4923 MADSVEGIGPFDELGALDYLLHRGEANPRTRAGIMAVELL--DTTPDWNR
: :: . ..: : : .
Mflv_1058|M.gilvum_PYR-GCK GMIDEARRQEVVAPWNRRLAYPRLQFSPLHSWVTDEDFDFDYHVRRSALA
Mvan_5773|M.vanbaalenii_PYR-1 RMVDDARRQEVMPPWNRKLAYPRLQFSPLHTWVTDTEFDFDYHVRRSALA
MSMEG_6322|M.smegmatis_MC2_155 ELYEEMVRHTDFQPVFRKHPATLLGGIANVGWTLDDEVDLDYHLRRSALP
TH_2030|M.thermoresistible__bu GLHQRLAAGRELHPTFRKHPATLFGGIAHLGWAVDDDVDFDYHLRRSALP
Mb3761c|M.bovis_AF2122/97 EFTERLVANDEFQPMFRKHPATIGGGIARVAWAYDDDIDIDYHVRRSALP
Rv3734c|M.tuberculosis_H37Rv EFTERLVANDEFQPMFRKHPATIGGGIARVAWAYDDDIDIDYHVRRSALP
MMAR_5271|M.marinum_M NFYEALVANHEFQPTFRKHPATIGGGIARVAWAYDDDLDVDYHVRRSALP
MAV_0355|M.avium_104 DFYKQLVAQPDFQPTFRKHPAKFVGGIANLGWSYDADVDVDYHVRRSALP
MUL_4351|M.ulcerans_Agy99 ETHQAMLDCREVAPLFRKRPASFQGVLTNLGWSVDDDIDFGFHVRRSALP
MAB_4544c|M.abscessus_ATCC_199 VFYEQLMSTTEVSSDFRKRPGQPLAVMGNLTWIVDDEVDWEYHVRRSALP
MLBr_01244|M.leprae_Br4923 -FRSRIEDVSQRVLRLRQKVVVPTLPTAAPRWVVDPDFELDFHVRRVRVP
. *: * * :.: :*:** :.
Mflv_1058|M.gilvum_PYR-GCK SPGDERELGVLVSRLHSNHLDLTRPPWELHVIEGLEGGRFALYMKIHHAL
Mvan_5773|M.vanbaalenii_PYR-1 SPGDERELGILVSRLHSNHLDLTRPPWELHVIEGLEGGRFALYMKIHHAL
MSMEG_6322|M.smegmatis_MC2_155 SPGRPRELLELTSRVHGTLLDRHRPLWEAYLIEGMADGRFAVYTKVHHSL
TH_2030|M.thermoresistible__bu GPGRIRELLDLTSRWHGTLLDRHRPLWEVHLVEGLADGRVAIYFKVHHAL
Mb3761c|M.bovis_AF2122/97 SPGRVRDLLELTSRLHTSLLDRHRPLWELHVVEGLNDGRFAMYTKMHHAL
Rv3734c|M.tuberculosis_H37Rv SPGRVRDLLELTSRLHTSLLDRHRPLWELHVVEGLNDGRFAMYTKMHHAL
MMAR_5271|M.marinum_M SPGRVRDLLELTSRLHTSLLDRHRPLWELHVVEGLSDGRFAMYAKMHHAL
MAV_0355|M.avium_104 SPRRVRELLELTSRWHSSLLDRHRPLWETHIVEGLKDGRFAIYTKVHHAL
MUL_4351|M.ulcerans_Agy99 APGRVRELLELTSRLHAHLLDRHRPLWETHVIEGLNDGRFAIYSKMHHAL
MAB_4544c|M.abscessus_ATCC_199 RPARVRELLTVTSRWHSSPLDRHRPLWEMHVVEGLSDGRLAVYTKMHHAV
MLBr_01244|M.leprae_Br4923 DPGTLREVFDLAEVIQQSPMDVSRPLWTATLVEGLAAGRAAMLLQISHAI
* *:: :.. : :* ** * ::**: ** *: :: *::
Mflv_1058|M.gilvum_PYR-GCK VDGYSAMRMLGRSLSTDPASRDTRMFFNVPSPTRSRRDPGAAESSNPLTA
Mvan_5773|M.vanbaalenii_PYR-1 VDGYTAMRMLGRSLSTDPETRDARMFFNVPIPKRSRPTGAGAQSSNPVTA
MSMEG_6322|M.smegmatis_MC2_155 IDGVSAMKLVERTLSEDPSDTTVRVPWNLPRR-ESSRRA-------GSSS
TH_2030|M.thermoresistible__bu IDGVAVMKLMQRTLSTDPGDD-ARVPWNLPPP-RRNP-A-------GPVS
Mb3761c|M.bovis_AF2122/97 IDGVSAMKLAQRTLSADPDDAEVRAIWNLPPRPRTRPPS-------DGSS
Rv3734c|M.tuberculosis_H37Rv IDGVSAMKLAQRTLSADPDDAEVRAIWNLPPRPRTRPPS-------DGSS
MMAR_5271|M.marinum_M IDGVSAAKLMQRTMSADPSDTEVRAMWNLPRPPRPESNG-------GGSS
MAV_0355|M.avium_104 IDGVSAQKLMQRALSSDPDDPEIRAPWTLPKRSRKAGP----------SS
MUL_4351|M.ulcerans_Agy99 IDGVSGLALMRRSLPADPADTNFRATWS-PAPERPRGVQ-------TRPG
MAB_4544c|M.abscessus_ATCC_199 IDGVGALRMMMRSLSDDPDARDCQAVWAPAKRRAKSSIVSTTNT--SAID
MLBr_01244|M.leprae_Br4923 TDGVGSVEMFAEMYDLERDPPSRPRSPQPIPQDLSRNDLMLQGINHLPVA
** : . :
Mflv_1058|M.gilvum_PYR-GCK TLRALGGVSSAVTGGVSSAVDLTNALVNTQIRRDGENAHIAGSVSAPHSI
Mvan_5773|M.vanbaalenii_PYR-1 TLRALGAVGSTVSDGVGSAVDLASALVNTQIRRDGDFGRISGSASAPHSI
MSMEG_6322|M.smegmatis_MC2_155 LARTATGAATSLAALAPSTIRLARAALLEQQ--------LTLPFGAPRTM
TH_2030|M.thermoresistible__bu RLRSATGAVGSVAALAPSTLSLARAALLEQR--------LTLPFGAPRTM
Mb3761c|M.bovis_AF2122/97 LLDALFKMAGSVVGLAPSTLKLARAALLEQQ--------LTLPFAAPHSM
Rv3734c|M.tuberculosis_H37Rv LLDALFKMAGSVVGLAPSTLKLARAALLEQQ--------LTLPFAAPHSM
MMAR_5271|M.marinum_M LVGSLVKMAGSVAGLAPSTLKLARAALFEQQ--------LTLPFAAPHTM
MAV_0355|M.avium_104 RLSSLVHAAGSVAALAPSTVSLARAALVEQQ--------LTLPFGAPRTM
MUL_4351|M.ulcerans_Agy99 PLRQLGGMLGSVAGLAPSSLRLARSALLEQQ--------LTLPFATPRTM
MAB_4544c|M.abscessus_ATCC_199 LVKGAAGAVRQVVSIPPGLLKYGRHALSDPQ--------LVKPLSAPHTM
MLBr_01244|M.leprae_Br4923 LAGGVVGGLSGVASVAGRAILRPASTVSGVVGYVRSGIRVLSQAAEPSPL
: : : : . * .:
Mflv_1058|M.gilvum_PYR-GCK LNARISRNRRFATQQYEFDRLKKLSSQHGATLNDVALAIIGGGLRKFLSD
Mvan_5773|M.vanbaalenii_PYR-1 LNARISRNRRFATQQYEFDRLKKLSSQHGATINDVALAIIGGGLRKFLAD
MSMEG_6322|M.smegmatis_MC2_155 FNVKIGGARRVAAQSWPLERLRRIKAVTGATINDIVLAMCAGALRAYLAE
TH_2030|M.thermoresistible__bu FNVRIGGARRVAAQSWPLQRIRRIRQAAGXTLNDVALAMCAGALRQYLLE
Mb3761c|M.bovis_AF2122/97 FNVKVGGARRCAAQSWSLDRIKSVKQAAGVTVNDAVLAMCAGALRYYLIE
Rv3734c|M.tuberculosis_H37Rv FNVKVGGARRCAAQSWSLDRIKSVKQAAGVTVNDAVLAMCAGALRYYLIE
MMAR_5271|M.marinum_M FNVKVGGARRCAAQSWSLERIRAVKQAAGVTVNDAVLAMCAGALRYYLIE
MAV_0355|M.avium_104 LNVKIGGARRCAAQSWPLERIKNVKNAAGVTVNDVVLAMCSGALRYYLLE
MUL_4351|M.ulcerans_Agy99 LNVAIGGARRCAAQSWDIDRVETVKNAAGVSLNDVVLAMCAGALRCYLED
MAB_4544c|M.abscessus_ATCC_199 LNVSIGGARRFAAQTWSMARIKEAGKALGGTVNDVVLAMCGGALRTYLEE
MLBr_01244|M.leprae_Br4923 LRQRS-LATRTEAIEIQLSDLHKAAKAGDGSINDAYLAGLVGALRRYHEA
:. * : : :. . ::** ** *.** :
Mflv_1058|M.gilvum_PYR-GCK FDKLPDRSLIAFLPVNVRPKGDE-GGGNAVGAILAP-MGTDIEDPVERLD
Mvan_5773|M.vanbaalenii_PYR-1 LGELPDRSLIAFLPVNVRPKGDE-GGGNAVGAILAP-MGTDIEDPVERLA
MSMEG_6322|M.smegmatis_MC2_155 QDALPDRPLIAMVPVSMRSEHEADAGGNMVGSILCS-LGTDVEDPADRLA
TH_2030|M.thermoresistible__bu HDALPATPLVAMVPVSLRSADESAGGGNRTGLVLCN-LATDSDDPAERLD
Mb3761c|M.bovis_AF2122/97 RNALPDRPLIAMVPVSLRSKEDADAGGNLVGSVLCN-LATHVDDPAQRIQ
Rv3734c|M.tuberculosis_H37Rv RNALPDRPLIAMVPVSLRSKEDADAGGNLVGSVLCN-LATHVDDPAQRIQ
MMAR_5271|M.marinum_M QDALPDAPLIAMVPVSLRSKEQADSGGNMVGSVLCN-LGTNVEDPAQRIE
MAV_0355|M.avium_104 QNALPDTPLIAMVPVSLRTEEEADAGGNLVGAILCN-LATDSDDPAQRLL
MUL_4351|M.ulcerans_Agy99 NDALPDAPLVAMVRVSLRTERDS-VGGNMVGAVLCN-LATHLDDPAQRLA
MAB_4544c|M.abscessus_ATCC_199 QNALPDKPLVAMCPVSIRAEGDQNAGNSIT-ALLAN-LATDKPDPLERFS
MLBr_01244|M.leprae_Br4923 LGVSIS-TLPMAVPVNVRTEADVVGSNRFVGVTLAAPLGTN--DPAARMQ
. .* *.:*. : .. . *. :.*. ** *:
Mflv_1058|M.gilvum_PYR-GCK TITTATRAAKGQLQSMSPAAIIAYSAALLAPAGSQIAGALTGVQPPWPYT
Mvan_5773|M.vanbaalenii_PYR-1 VITAATRASKAQLQSMSPAAIIAYSAALLAPAGGQIAGALTGVNPPWPHT
MSMEG_6322|M.smegmatis_MC2_155 VIRRSITDNKRVFSELPRLQALALSALLIAPL--GLTTAFPGFVDATAPP
TH_2030|M.thermoresistible__bu RISSSMRSNKRVFSQLPRVQAMALSAAMIAPL--GLG-AVPGVVSSAPPP
Mb3761c|M.bovis_AF2122/97 TISASMDGNKKVLSELPQLQVLALSALNMAPL--TLA-GVPGFLSAVPPP
Rv3734c|M.tuberculosis_H37Rv TISASMDGNKKVLSELPQLQVLALSALNMAPL--TLA-GVPGFLSAVPPP
MMAR_5271|M.marinum_M IISASMRANKKVLADLPRLQVLALSGLNMAPL--TLA-GVPGFLSTVPPP
MAV_0355|M.avium_104 TISESMRSNKKVFSQLPRFQALALSAANLSSL--ALA-AVPGWVSATSPP
MUL_4351|M.ulcerans_Agy99 VIHASMRDNKKVLAQLPRAQALALSLLLLSPA--ALN-TLPGLSTVTPPP
MAB_4544c|M.abscessus_ATCC_199 AIRDSVQAAKSVLSEMTPLQRMLVGALNGAPV--LTG-AVPGLVDRTAPA
MLBr_01244|M.leprae_Br4923 KIRSQMTQRR----DEPAMNIIGS----LAPLMTVLPASVLDFIVDSVAS
* : . . : :. . . .
Mflv_1058|M.gilvum_PYR-GCK FNLCVSNVPGPREPLYFNGSRLEATYPVSIPIHGMALNITLQSYADTMNL
Mvan_5773|M.vanbaalenii_PYR-1 FNLCVSNVPGPREPLYFNGSRLEATFPVSIPIHGMALNITLQSYADTMNL
MSMEG_6322|M.smegmatis_MC2_155 FNLVISNVPGPKKPLYWRGARLAGNYPLSIALDGQALNMTVVSNAHNLDF
TH_2030|M.thermoresistible__bu FNLVISNVPGAPEPRYWMGARLAGNYPLSIVLDGQALNITLVTNADNLDF
Mb3761c|M.bovis_AF2122/97 FNIVISNVPGPVDPLYYGTARLDGSYPLSNIPDGQALNITLVNNAGNLDF
Rv3734c|M.tuberculosis_H37Rv FNIVISNVPGPVDPLYYGTARLDGSYPLSNIPDGQALNITLVNNAGNLDF
MMAR_5271|M.marinum_M FNIVISNVPGGAQPLYYGGARLDGSYPLSNIPDGQALNITLVNNADRLDF
MAV_0355|M.avium_104 FNIVISNVPGPTAPLYYGGARLDGNYPLSIVLDGQALNITLASNAGNLDF
MUL_4351|M.ulcerans_Agy99 FNVCISNVPGVREPRYFNGARLVGNYPLSLPINGQALNITLTSTADRLDF
MAB_4544c|M.abscessus_ATCC_199 FNVIISNVPGPRTDMFWNGFEMDGCYPASIPIDGVALNITCTSSGSSMHF
MLBr_01244|M.leprae_Br4923 SDVNASNIPAYPGDTYFAGAKILRQYGIGPRP-GVAMMAVLMSRGGFCTV
:: **:*. :: .: : . * *: . . . .
Mflv_1058|M.gilvum_PYR-GCK GFVGCRDRLPHLQRLAVYTGDALAELEAASQI------------------
Mvan_5773|M.vanbaalenii_PYR-1 GFVGCRDRLPRLQRLAVYTGDALGELEAASS-------------------
MSMEG_6322|M.smegmatis_MC2_155 GLVGCRRSVPHLQRLLGHLETSLKDLETATGA------------------
TH_2030|M.thermoresistible__bu GLVGARGSVPHLQRLLGHLEDSLQQLERAVGG------------------
Mb3761c|M.bovis_AF2122/97 GLVGCRRSVPHLQRLLAHLESSLKDLEQAVGI------------------
Rv3734c|M.tuberculosis_H37Rv GLVGCRRSVPHLQRLLAHLESSLKDLEQAVGI------------------
MMAR_5271|M.marinum_M GLVGCRRSVPSLQRLLGHLETSLKDLEQAVGV------------------
MAV_0355|M.avium_104 GLVGCRRSVPHLQRLLMHLESSLKDLERAVGE------------------
MUL_4351|M.ulcerans_Agy99 GLVGCRSSVPHLQRMLGHLETSLKELERAVGL------------------
MAB_4544c|M.abscessus_ATCC_199 GLTGCRTSVPHLQRILAHLEDALTQLEESVA-------------------
MLBr_01244|M.leprae_Br4923 TVRYDRASVKSEALFARCLLEGFDEVLALAGDPTPHAVPASFAARSSGSP
. * : : .: ::
Mflv_1058|M.gilvum_PYR-GCK -------
Mvan_5773|M.vanbaalenii_PYR-1 -------
MSMEG_6322|M.smegmatis_MC2_155 -------
TH_2030|M.thermoresistible__bu -------
Mb3761c|M.bovis_AF2122/97 -------
Rv3734c|M.tuberculosis_H37Rv -------
MMAR_5271|M.marinum_M -------
MAV_0355|M.avium_104 -------
MUL_4351|M.ulcerans_Agy99 -------
MAB_4544c|M.abscessus_ATCC_199 -------
MLBr_01244|M.leprae_Br4923 AGWLSSS