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NAAIPPLDLGWLLMESPGGTTHVGAMLLFKKPPGRGSLVREIVEAYRGYRPLPPFNYVPELLGAGAPHFR EAESWDPHYHVQHLSLPAHSSYEDLLRLVADLHEPMLDRHRPMFRCWLIDGVPGGRFAIYTKTHHSIIDG VSGLRKLYEGLTLSAEPAIPTPPFAMPHPKSEAAAPTPALRKLTHAIHTAVTQIGAVNQISLGASRKALS AVLGSHVEGSLPFVASHAPTNAPPRQARGFATLSLPLQEMHRIGRRHGATLNDLAAAVIDHGLHSYLREV GQDHPHEFIAMCPVSLREDGDSAVGTRVSAIFVRLGKPEASMVDRLRQVARSVAIAKEELGALSADAAMT YAVALVALAGAGASTHLDRVGHPACNLVISNIPGGNATRYLNGAQLMGIFPVSALAASIGLNVTLTSYCD HMDFGFVANTAAISDVHALAEHTRRAFAECTAKTRVT*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2903 | - | - | 100% (458) | hypothetical protein Mvan_2903 |
| M. vanbaalenii PYR-1 | Mvan_5773 | - | 8e-52 | 30.77% (455) | hypothetical protein Mvan_5773 |
| M. vanbaalenii PYR-1 | Mvan_0444 | - | 9e-43 | 30.57% (471) | hypothetical protein Mvan_0444 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3115 | - | 2e-54 | 31.40% (465) | hypothetical protein Mb3115 |
| M. gilvum PYR-GCK | Mflv_1058 | - | 5e-53 | 31.41% (468) | hypothetical protein Mflv_1058 |
| M. tuberculosis H37Rv | Rv3088 | - | 2e-54 | 31.40% (465) | hypothetical protein Rv3088 |
| M. leprae Br4923 | MLBr_01244 | - | 2e-12 | 21.43% (364) | hypothetical protein MLBr_01244 |
| M. abscessus ATCC 19977 | MAB_4544c | - | 3e-42 | 27.31% (465) | hypothetical protein MAB_4544c |
| M. marinum M | MMAR_3403 | - | 1e-178 | 68.67% (450) | hypothetical protein MMAR_3403 |
| M. avium 104 | MAV_0355 | - | 7e-48 | 31.35% (453) | bifunctional wax ester synthase/acyl-coadiacylglycerol |
| M. smegmatis MC2 155 | MSMEG_6322 | - | 4e-49 | 32.17% (457) | bifunctional wax ester synthase/acyl-CoA diacylglycerol |
| M. thermoresistible (build 8) | TH_2030 | - | 6e-53 | 32.96% (446) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_4351 | - | 2e-47 | 31.43% (455) | hypothetical protein MUL_4351 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_2903|M.vanbaalenii_PYR-1 ---MNAAIPPLDLG----WLLMESPGGTTHVGAMLLFKKP-PGRG-SLVR
MMAR_3403|M.marinum_M ---MTKPIPPLDLS----WLLLESPAGTTHVGAMLLFKKP-FGR--DPVD
Mb3115|M.bovis_AF2122/97 ----MTRINPIDLS----FLLLERANRPNHMAAYTIFEKP-KGQKSSFGP
Rv3088|M.tuberculosis_H37Rv ----MTRINPIDLS----FLLLERANRPNHMAAYTIFEKP-KGQKSSFGP
MSMEG_6322|M.smegmatis_MC2_155 -MNRMQLMSPTDSM----FLIAESREHPMHVGGLALYDPP-DDAGPEFVR
TH_2030|M.thermoresistible__bu ----MRLISPADSM----FLLAESREHPMHVAGLQLFEPPPGTAGPEFLQ
MAV_0355|M.avium_104 ----MELIMPTDAV----FLLGESREHPMHVGGLQLYQPP-EGAGRNFVR
MUL_4351|M.ulcerans_Agy99 -------MSPVDAL----FLSAESREHPLHVGALQLFEPP-EGAGRAFVH
MAB_4544c|M.abscessus_ATCC_199 ----MPFMPVSDSM----FLIGETREHPFHVGGLQLFKPP-VDAGPDYAE
Mflv_1058|M.gilvum_PYR-GCK MSANSVRLGLQDLM----FIYGETSSSKMHVGGLLPFTPP-ADAPRDYLR
MLBr_01244|M.leprae_Br4923 MADSVEGIGPFDELGALDYLLHRGEANPRTRAGIMAVELLDTTPDWNRFR
: * :: . ..
Mvan_2903|M.vanbaalenii_PYR-1 EIVEAYRGYRPLPPFN---YVPELLGAGAPHFREAESWDPHYHVQHLSLP
MMAR_3403|M.marinum_M EIVAAYRGCSPTPPFN---YVPELLVRGAPHFREVANWDPHYHVGHLALP
Mb3115|M.bovis_AF2122/97 RLFDAYRHSQAAKPFN---HKLKWLGTDVAAWETVEP-DMGYHIRHLALP
Rv3088|M.tuberculosis_H37Rv RLFDAYRHSQAAKPFN---HKLKWLGTDVAAWETVEP-DMGYHIRHLALP
MSMEG_6322|M.smegmatis_MC2_155 ELYEEMVRHTDFQPVFRKHPATLLGGIANVGWTLDDEVDLDYHLRRSALP
TH_2030|M.thermoresistible__bu GLHQRLAAGRELHPTFRKHPATLFGGIAHLGWAVDDDVDFDYHLRRSALP
MAV_0355|M.avium_104 DFYKQLVAQPDFQPTFRKHPAKFVGGIANLGWSYDADVDVDYHVRRSALP
MUL_4351|M.ulcerans_Agy99 ETHQAMLDCREVAPLFRKRPASFQGVLTNLGWSVDDDIDFGFHVRRSALP
MAB_4544c|M.abscessus_ATCC_199 VFYEQLMSTTEVSSDFRKRPGQPLAVMGNLTWIVDDEVDWEYHVRRSALP
Mflv_1058|M.gilvum_PYR-GCK GMIDEARRQEVVAPWNRRLAYPRLQFSPLHSWVTDEDFDFDYHVRRSALA
MLBr_01244|M.leprae_Br4923 SRIEDVSQR---VLRLRQKVVVPTLPTAAPRWVVDPDFELDFHVRRVRVP
: : :*: : :.
Mvan_2903|M.vanbaalenii_PYR-1 AHSSYEDLLRLVADLHEPMLDRHRPMFRCWLIDGVPGGRFAIYTKTHHSI
MMAR_3403|M.marinum_M AGAGYDDLLRLVADLHEPQLDRHRPLFRCWVIDGVPDDMFAIYTKTHHSI
Mb3115|M.bovis_AF2122/97 APGSMQQFHETVSFLNTGLLDRGHPMWECYIIDGIERGRIAILLKVHHAL
Rv3088|M.tuberculosis_H37Rv APGSMQQFHETVSFLNTGLLDRGHPMWECYIIDGIERGRIAILLKVHHAL
MSMEG_6322|M.smegmatis_MC2_155 SPGRPRELLELTSRVHGTLLDRHRPLWEAYLIEGMADGRFAVYTKVHHSL
TH_2030|M.thermoresistible__bu GPGRIRELLDLTSRWHGTLLDRHRPLWEVHLVEGLADGRVAIYFKVHHAL
MAV_0355|M.avium_104 SPRRVRELLELTSRWHSSLLDRHRPLWETHIVEGLKDGRFAIYTKVHHAL
MUL_4351|M.ulcerans_Agy99 APGRVRELLELTSRLHAHLLDRHRPLWETHVIEGLNDGRFAIYSKMHHAL
MAB_4544c|M.abscessus_ATCC_199 RPARVRELLTVTSRWHSSPLDRHRPLWEMHVVEGLSDGRLAVYTKMHHAV
Mflv_1058|M.gilvum_PYR-GCK SPGDERELGVLVSRLHSNHLDLTRPPWELHVIEGLEGGRFALYMKIHHAL
MLBr_01244|M.leprae_Br4923 DPGTLREVFDLAEVIQQSPMDVSRPLWTATLVEGLAAGRAAMLLQISHAI
:. . : :* :* : :::*: . *: : *::
Mvan_2903|M.vanbaalenii_PYR-1 IDGVSGLRKLYEGLTLS-AEPAIPTPPFAMPHPKSEAAAP-------TPA
MMAR_3403|M.marinum_M IDGESGLKRLYEGLSTS-DRDTIPKPAFALDAPVPEPHPP-------TPL
Mb3115|M.bovis_AF2122/97 IDGEGGLRAMRNFLSDS-PDDTTLAGPWMSAQGADRPRRTPATVSRRAQL
Rv3088|M.tuberculosis_H37Rv IDGEGGLRAMRNFLSDS-PDDTTLAGPWMSAQGADRPRRTPATVSRRAQL
MSMEG_6322|M.smegmatis_MC2_155 IDGVSAMKLVERTLSED-PSDTTVRVPWNLPRRESSRRAGSSS-------
TH_2030|M.thermoresistible__bu IDGVAVMKLMQRTLSTD-PGDD-ARVPWNLPPPRRNP-AGPVS-------
MAV_0355|M.avium_104 IDGVSAQKLMQRALSSD-PDDPEIRAPWTLP--KRSRKAGPSS-------
MUL_4351|M.ulcerans_Agy99 IDGVSGLALMRRSLPAD-PADTNFRATWSPAPERPRGVQTRPG-------
MAB_4544c|M.abscessus_ATCC_199 IDGVGALRMMMRSLSDD-PDARDCQAVWAPAKRRAKSSIVSTTN-----T
Mflv_1058|M.gilvum_PYR-GCK VDGYSAMRMLGRSLSTD-PASRDTRMFFNVPSPTRSRRDPGAAE-----S
MLBr_01244|M.leprae_Br4923 TDGVGSVEMFAEMYDLERDPPSRPRSPQPIPQDLSRNDLMLQG------I
** . . . .
Mvan_2903|M.vanbaalenii_PYR-1 LRKLTHAIHTAVTQIGAVNQISLGASRKALSAVLGSHV------EGSLPF
MMAR_3403|M.marinum_M AEKVAHSIRGAVTEFTALNQVAVGAARKVLSGLLGSHL------EGSLPF
Mb3115|M.bovis_AF2122/97 QGQLQGMIKGLTKLPSGLFGVSADAADLGAQALSLKAR------KASLPF
Rv3088|M.tuberculosis_H37Rv QGQLQGMIKGLTKLPSGLFGVSADAADLGAQALSLKAR------KASLPF
MSMEG_6322|M.smegmatis_MC2_155 ------LARTATGAATSLAALAPSTIRLARAALLEQQ--------LTLPF
TH_2030|M.thermoresistible__bu ------RLRSATGAVGSVAALAPSTLSLARAALLEQR--------LTLPF
MAV_0355|M.avium_104 ------RLSSLVHAAGSVAALAPSTVSLARAALVEQQ--------LTLPF
MUL_4351|M.ulcerans_Agy99 ------PLRQLGGMLGSVAGLAPSSLRLARSALLEQQ--------LTLPF
MAB_4544c|M.abscessus_ATCC_199 SA--IDLVKGAAGAVRQVVSIPPGLLKYGRHALSDPQ--------LVKPL
Mflv_1058|M.gilvum_PYR-GCK SNPLTATLRALGGVSSAVTGGVSSAVDLTNALVNTQIRRDGENAHIAGSV
MLBr_01244|M.leprae_Br4923 NHLPVALAGGVVGGLSGVASVAGRAILRPASTVSGVVGYVRSGIRVLSQA
: :
Mvan_2903|M.vanbaalenii_PYR-1 VASHAPTN-APPRQARGFATLSLPLQEMHRIGRRHGATLNDLAAAVIDHG
MMAR_3403|M.marinum_M VAQHAPTN-APLEIGRRFATLSLPLAEMREIGHHFGATLNDVAASVIDGG
Mb3115|M.bovis_AF2122/97 TARRTLFNNTAKSAARAYGNVELPLADVKALAKATGTSVNDVVMTVIDDA
Rv3088|M.tuberculosis_H37Rv TARRTLFNNTAKSAARAYGNVELPLADVKALAKATGTSVNDVVMTVIDDA
MSMEG_6322|M.smegmatis_MC2_155 GAPRTMFN-VKIGGARRVAAQSWPLERLRRIKAVTGATINDIVLAMCAGA
TH_2030|M.thermoresistible__bu GAPRTMFN-VRIGGARRVAAQSWPLQRIRRIRQAAGXTLNDVALAMCAGA
MAV_0355|M.avium_104 GAPRTMLN-VKIGGARRCAAQSWPLERIKNVKNAAGVTVNDVVLAMCSGA
MUL_4351|M.ulcerans_Agy99 ATPRTMLN-VAIGGARRCAAQSWDIDRVETVKNAAGVSLNDVVLAMCAGA
MAB_4544c|M.abscessus_ATCC_199 SAPHTMLN-VSIGGARRFAAQTWSMARIKEAGKALGGTVNDVVLAMCGGA
Mflv_1058|M.gilvum_PYR-GCK SAPHSILN-ARISRNRRFATQQYEFDRLKKLSSQHGATLNDVALAIIGGG
MLBr_01244|M.leprae_Br4923 AEPSPLLR--QRSLATRTEAIEIQLSDLHKAAKAGDGSINDAYLAGLVGA
. . : :. . ::** : .
Mvan_2903|M.vanbaalenii_PYR-1 LHSYLREVGQDHPHEFIAMCPVSLREDGDS-AVGTRVSAIFVRLGKPEAS
MMAR_3403|M.marinum_M LHAYLRETEREFAHPFIAMCPVSLRADDDT-TIGTRVSAIFVRLGQPRAS
Mb3115|M.bovis_AF2122/97 LHHYLAEHQASTDRPLVAFMPMSLREKSGE-GGGNRVSAELVPMGAPKAS
Rv3088|M.tuberculosis_H37Rv LHHYLAEHQASTDRPLVAFMPMSLREKSGE-GGGNRVSAELVPMGAPKAS
MSMEG_6322|M.smegmatis_MC2_155 LRAYLAEQDALPDRPLIAMVPVSMRSEHEADAGGNMVGSILCSLGTDVED
TH_2030|M.thermoresistible__bu LRQYLLEHDALPATPLVAMVPVSLRSADESAGGGNRTGLVLCNLATDSDD
MAV_0355|M.avium_104 LRYYLLEQNALPDTPLIAMVPVSLRTEEEADAGGNLVGAILCNLATDSDD
MUL_4351|M.ulcerans_Agy99 LRCYLEDNDALPDAPLVAMVRVSLRTERDS-VGGNMVGAVLCNLATHLDD
MAB_4544c|M.abscessus_ATCC_199 LRTYLEEQNALPDKPLVAMCPVSIRAEGDQNAGNSIT-ALLANLATDKPD
Mflv_1058|M.gilvum_PYR-GCK LRKFLSDFDKLPDRSLIAFLPVNVRPKGDE-GGGNAVGAILAPMGTDIED
MLBr_01244|M.leprae_Br4923 LRRYHEALGVSIS-TLPMAVPVNVRTEADVVGSNRFVGVTLAAP-LGTND
*: : : :.:* . . : .
Mvan_2903|M.vanbaalenii_PYR-1 MVDRLRQVARSVAIAKEELGALSADAAMTYAVALVALAGAG---ASTHLD
MMAR_3403|M.marinum_M MPERIGQVMNSVATAKKELGAMSKEAAMTYAVGLVALAGVG---ASTHLD
Mb3115|M.bovis_AF2122/97 PVERLKEINAATTRAKDKGRGMQTTSRQAYALLLLGSLTVA---DALPLL
Rv3088|M.tuberculosis_H37Rv PVERLKEINAATTRAKDKGRGMQTTSRQAYALLLLGSLTVA---DALPLL
MSMEG_6322|M.smegmatis_MC2_155 PADRLAVIRRSITDNKRVFSELPRLQALALSALLIAPLGLTT--AFPGFV
TH_2030|M.thermoresistible__bu PAERLDRISSSMRSNKRVFSQLPRVQAMALSAAMIAPLGLG---AVPGVV
MAV_0355|M.avium_104 PAQRLLTISESMRSNKKVFSQLPRFQALALSAANLSSLALA---AVPGWV
MUL_4351|M.ulcerans_Agy99 PAQRLAVIHASMRDNKKVLAQLPRAQALALSLLLLSPAALN---TLPGLS
MAB_4544c|M.abscessus_ATCC_199 PLERFSAIRDSVQAAKSVLSEMTPLQRMLVGALNGAPVLTG---AVPGLV
Mflv_1058|M.gilvum_PYR-GCK PVERLDTITTATRAAKGQLQSMSPAAIIAYSAALLAPAGSQIAGALTGVQ
MLBr_01244|M.leprae_Br4923 PAARMQKIRSQMTQRRDE----PAMNIIGSLAPLMTVLPAS----VLDFI
*: : :
Mvan_2903|M.vanbaalenii_PYR-1 RVGHPACNLVISNIPGGNATRYLNGAQLMGIFPVSALAASIGLNVTLTSY
MMAR_3403|M.marinum_M RIAHPACNLVISNVAGASDIRYLNGARLLGIYPVSALAAAIGLNATLASY
Mb3115|M.bovis_AF2122/97 G-KLPSANVVISNMKGPTEQLYLAGAPLVAFSGLPIVPPGAGLNVTFASI
Rv3088|M.tuberculosis_H37Rv G-KLPSANVVISNMKGPTEQLYLAGAPLVAFSGLPIVPPGAGLNVTFASI
MSMEG_6322|M.smegmatis_MC2_155 DATAPPFNLVISNVPGPKKPLYWRGARLAGNYPLSIALDGQALNMTVVSN
TH_2030|M.thermoresistible__bu SSAPPPFNLVISNVPGAPEPRYWMGARLAGNYPLSIVLDGQALNITLVTN
MAV_0355|M.avium_104 SATSPPFNIVISNVPGPTAPLYYGGARLDGNYPLSIVLDGQALNITLASN
MUL_4351|M.ulcerans_Agy99 TVTPPPFNVCISNVPGVREPRYFNGARLVGNYPLSLPINGQALNITLTST
MAB_4544c|M.abscessus_ATCC_199 DRTAPAFNVIISNVPGPRTDMFWNGFEMDGCYPASIPIDGVALNITCTSS
Mflv_1058|M.gilvum_PYR-GCK PPWPYTFNLCVSNVPGPREPLYFNGSRLEATYPVSIPIHGMALNITLQSY
MLBr_01244|M.leprae_Br4923 VDSVASSDVNASNIPAYPGDTYFAGAKILRQYGIG-PRPGVAMMAVLMSR
. :: **: . : * : . .: . :
Mvan_2903|M.vanbaalenii_PYR-1 CDHMDFGFVANTAAISDVHALAEHTRRAFAEC-----TAKTRVT------
MMAR_3403|M.marinum_M HDNMDFGFIANAAAIEDPTRLADLTLRAYEELRDAAGTAAGRSQRASR--
Mb3115|M.bovis_AF2122/97 NTALCIAIGAAPEAVHEPSRLAELMQRAFTELQTEAGTTSPTTSKSRTP-
Rv3088|M.tuberculosis_H37Rv NTALCIAIGAAPEAVHEPSRLAELMQRAFTELQTEAGTTSPTTSKSRTP-
MSMEG_6322|M.smegmatis_MC2_155 AHNLDFGLVGCRRSVPHLQRLLGHLETSLKDLETATGA------------
TH_2030|M.thermoresistible__bu ADNLDFGLVGARGSVPHLQRLLGHLEDSLQQLERAVGG------------
MAV_0355|M.avium_104 AGNLDFGLVGCRRSVPHLQRLLMHLESSLKDLERAVGE------------
MUL_4351|M.ulcerans_Agy99 ADRLDFGLVGCRSSVPHLQRMLGHLETSLKELERAVGL------------
MAB_4544c|M.abscessus_ATCC_199 GSSMHFGLTGCRTSVPHLQRILAHLEDALTQLEESVA-------------
Mflv_1058|M.gilvum_PYR-GCK ADTMNLGFVGCRDRLPHLQRLAVYTGDALAELEAASQI------------
MLBr_01244|M.leprae_Br4923 GGFCTVTVRYDRASVKSEALFARCLLEGFDEVLALAGDPTPHAVPASFAA
. . : : . :
Mvan_2903|M.vanbaalenii_PYR-1 -------------
MMAR_3403|M.marinum_M -------------
Mb3115|M.bovis_AF2122/97 -------------
Rv3088|M.tuberculosis_H37Rv -------------
MSMEG_6322|M.smegmatis_MC2_155 -------------
TH_2030|M.thermoresistible__bu -------------
MAV_0355|M.avium_104 -------------
MUL_4351|M.ulcerans_Agy99 -------------
MAB_4544c|M.abscessus_ATCC_199 -------------
Mflv_1058|M.gilvum_PYR-GCK -------------
MLBr_01244|M.leprae_Br4923 RSSGSPAGWLSSS