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MRNHLQHIVLPGPGSMAQFYETVSFLNTGLLDRGHPLWECYIIDGIEGGRIAIMLKVHHALIDGEGGLRA MRGFLSTSPHDKTLAGPWMPAPSARAPRRQWLQRGLTGIAKLPSDLAGMVGDAVDLGAQALQLKPQRGAL PFAASPTLLNHTAKSAARAYANMELPLAEVKAVAKATDTSINDVVMTIVDDALHHYLDEHRAPADGPLVA LMPMSMRSQAGAGNQVSAELIAMGAPKANLRQRLKQVSQATTAAKDKGDGMKSPSRQAYTLSLFASLAMS DVLPGFGKAPSANLVISNMKGPAEQLYLAGAPMVSFGGLPILPPGAGLNVTVASVNEQLCLGIGAAPEAV REPARLAQLIEQAFGQLQADIGRSAPAIAGHQADSA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_3162 | - | - | 100% (386) | hypothetical protein MUL_3162 |
| M. ulcerans Agy99 | MUL_4351 | - | 1e-43 | 33.85% (384) | hypothetical protein MUL_4351 |
| M. ulcerans Agy99 | MUL_1193 | - | 1e-42 | 32.80% (378) | hypothetical protein MUL_1193 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3115 | - | 1e-145 | 66.15% (390) | hypothetical protein Mb3115 |
| M. gilvum PYR-GCK | Mflv_0349 | - | 5e-37 | 30.67% (388) | hypothetical protein Mflv_0349 |
| M. tuberculosis H37Rv | Rv3088 | - | 1e-145 | 66.15% (390) | hypothetical protein Rv3088 |
| M. leprae Br4923 | MLBr_01244 | - | 5e-16 | 24.01% (404) | hypothetical protein MLBr_01244 |
| M. abscessus ATCC 19977 | MAB_4544c | - | 4e-40 | 29.18% (377) | hypothetical protein MAB_4544c |
| M. marinum M | MMAR_2598 | - | 0.0 | 96.70% (394) | hypothetical protein MMAR_2598 |
| M. avium 104 | MAV_0355 | - | 3e-45 | 33.33% (375) | bifunctional wax ester synthase/acyl-coadiacylglycerol |
| M. smegmatis MC2 155 | MSMEG_6322 | - | 2e-46 | 35.19% (378) | bifunctional wax ester synthase/acyl-CoA diacylglycerol |
| M. thermoresistible (build 8) | TH_2030 | - | 1e-43 | 32.45% (379) | CONSERVED HYPOTHETICAL PROTEIN |
| M. vanbaalenii PYR-1 | Mvan_2903 | - | 6e-44 | 31.38% (376) | hypothetical protein Mvan_2903 |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_3162|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2598|M.marinum_M --MNTNRISPIDLS----FLLLERPNRPFHMTAFTIFQKPKG-----QHS
Mb3115|M.bovis_AF2122/97 ----MTRINPIDLS----FLLLERANRPNHMAAYTIFEKPKG-----QKS
Rv3088|M.tuberculosis_H37Rv ----MTRINPIDLS----FLLLERANRPNHMAAYTIFEKPKG-----QKS
MAV_0355|M.avium_104 ----MELIMPTDAV----FLLGESREHPMHVGGLQLYQPPEG-AGRNFVR
MSMEG_6322|M.smegmatis_MC2_155 -MNRMQLMSPTDSM----FLIAESREHPMHVGGLALYDPPDD-AGPEFVR
TH_2030|M.thermoresistible__bu ----MRLISPADSM----FLLAESREHPMHVAGLQLFEPPPGTAGPEFLQ
MAB_4544c|M.abscessus_ATCC_199 ----MPFMPVSDSM----FLIGETREHPFHVGGLQLFKPPVD-AGPDYAE
Mflv_0349|M.gilvum_PYR-GCK -----MRLSSVDAA----FWFAENLKWHMHIGAIALCD-PSDVPDFGFEQ
Mvan_2903|M.vanbaalenii_PYR-1 ---MNAAIPPLDLG----WLLMESPGGTTHVGAMLLFKKPPG-----RGS
MLBr_01244|M.leprae_Br4923 MADSVEGIGPFDELGALDYLLHRGEANPRTRAGIMAVELLDT---TPDWN
MUL_3162|M.ulcerans_Agy99 ---------------------------------------MRNHLQHIVLP
MMAR_2598|M.marinum_M SFGSRLFDAYRHSRAIEPFNYRLSWLGRNVARWEIVEPDMRNHVQHIVLP
Mb3115|M.bovis_AF2122/97 SFGPRLFDAYRHSQAAKPFNHKLKWLGTDVAAWETVEPDMGYHIRHLALP
Rv3088|M.tuberculosis_H37Rv SFGPRLFDAYRHSQAAKPFNHKLKWLGTDVAAWETVEPDMGYHIRHLALP
MAV_0355|M.avium_104 DFYKQLVAQPDFQPTFRKHPAKFVGGIANLGWSYDADVDVDYHVRRSALP
MSMEG_6322|M.smegmatis_MC2_155 ELYEEMVRHTDFQPVFRKHPATLLGGIANVGWTLDDEVDLDYHLRRSALP
TH_2030|M.thermoresistible__bu GLHQRLAAGRELHPTFRKHPATLFGGIAHLGWAVDDDVDFDYHLRRSALP
MAB_4544c|M.abscessus_ATCC_199 VFYEQLMSTTEVSSDFRKRPGQPLAVMGNLTWIVDDEVDWEYHVRRSALP
Mflv_0349|M.gilvum_PYR-GCK VRDLIISRLPELPQLRWRVVGAPLG-LDRPYFVEDEDIDVDFHIRRIAVP
Mvan_2903|M.vanbaalenii_PYR-1 LVREIVEAYRGYRPLPPFNYVPELLGAGAPHFREAESWDPHYHVQHLSLP
MLBr_01244|M.leprae_Br4923 RFRSRIEDVSQRVLRLRQKVVVPTLPTAAPRWVVDPDFELDFHVRRVRVP
*::: :*
MUL_3162|M.ulcerans_Agy99 GPGSMAQFYETVSFLNTGLLDRGHPLWECYIIDGIEGGRIAIMLKVHHAL
MMAR_2598|M.marinum_M GPGSMAQFYETVSFLNTGLLDRGHPLWECYIIDGIEGGRIAIMLKVHHAL
Mb3115|M.bovis_AF2122/97 APGSMQQFHETVSFLNTGLLDRGHPMWECYIIDGIERGRIAILLKVHHAL
Rv3088|M.tuberculosis_H37Rv APGSMQQFHETVSFLNTGLLDRGHPMWECYIIDGIERGRIAILLKVHHAL
MAV_0355|M.avium_104 SPRRVRELLELTSRWHSSLLDRHRPLWETHIVEGLKDGRFAIYTKVHHAL
MSMEG_6322|M.smegmatis_MC2_155 SPGRPRELLELTSRVHGTLLDRHRPLWEAYLIEGMADGRFAVYTKVHHSL
TH_2030|M.thermoresistible__bu GPGRIRELLDLTSRWHGTLLDRHRPLWEVHLVEGLADGRVAIYFKVHHAL
MAB_4544c|M.abscessus_ATCC_199 RPARVRELLTVTSRWHSSPLDRHRPLWEMHVVEGLSDGRLAVYTKMHHAV
Mflv_0349|M.gilvum_PYR-GCK SPGGRKELDDLVGRLMSYKLDRSKPLWELWFIEGLEGGRVAVVTKMHHAV
Mvan_2903|M.vanbaalenii_PYR-1 AHSSYEDLLRLVADLHEPMLDRHRPMFRCWLIDGVPGGRFAIYTKTHHSI
MLBr_01244|M.leprae_Br4923 DPGTLREVFDLAEVIQQSPMDVSRPLWTATLVEGLAAGRAAMLLQISHAI
:. . :* :*:: .::*: ** *: : *::
MUL_3162|M.ulcerans_Agy99 IDGEGGLRAMRGFLST--SPHDKTLAGPWMPAPSARAPRR--------QW
MMAR_2598|M.marinum_M IDGEGGLRAMRGFLST--SPHDKTLAGPWMPAPSARAPRRPQPRVSRRQW
Mb3115|M.bovis_AF2122/97 IDGEGGLRAMRNFLSD--SPDDTTLAGPWMSAQGADRPRRTPATVSRRAQ
Rv3088|M.tuberculosis_H37Rv IDGEGGLRAMRNFLSD--SPDDTTLAGPWMSAQGADRPRRTPATVSRRAQ
MAV_0355|M.avium_104 IDGVSAQKLMQRALSS--DPDDPEIRAPWTLPKR--SRKAGPSS------
MSMEG_6322|M.smegmatis_MC2_155 IDGVSAMKLVERTLSE--DPSDTTVRVPWNLPRRESSRRAGSSS------
TH_2030|M.thermoresistible__bu IDGVAVMKLMQRTLST--DPGD-DARVPWNLPPPR-RNPAGPVS------
MAB_4544c|M.abscessus_ATCC_199 IDGVGALRMMMRSLSD--DPDARDCQAVWAPAKRRAKSSIVSTTNTSAID
Mflv_0349|M.gilvum_PYR-GCK VDGVSGAGISEILLDT--TPEPRPPAVDASRSLVGVKPPSRERQAVNG--
Mvan_2903|M.vanbaalenii_PYR-1 IDGVSGLRKLYEGLTL--SAEPAIPTPPFAMPHPKSEAAAPTPALRKLTH
MLBr_01244|M.leprae_Br4923 TDGVGSVEMFAEMYDLERDPPSRPRSPQPIPQDLSRNDLMLQGINHLPVA
** . .
MUL_3162|M.ulcerans_Agy99 LQRGLT----GIAKLPSDLAGMVGDAVDLGAQALQLKPQRGALPFAASPT
MMAR_2598|M.marinum_M LQRGLT----GIAKLPSDLVGMVGDAVDLGAQALQLKPQRGALPFAASPT
Mb3115|M.bovis_AF2122/97 LQGQLQGMIKGLTKLPSGLFGVSADAADLGAQALSLKARKASLPFTARRT
Rv3088|M.tuberculosis_H37Rv LQGQLQGMIKGLTKLPSGLFGVSADAADLGAQALSLKARKASLPFTARRT
MAV_0355|M.avium_104 RLSSLVHAAGSVAALAPSTVSLARAAL-VEQQLT--------LPFGAPRT
MSMEG_6322|M.smegmatis_MC2_155 LARTATGAATSLAALAPSTIRLARAAL-LEQQLT--------LPFGAPRT
TH_2030|M.thermoresistible__bu RLRSATGAVGSVAALAPSTLSLARAAL-LEQRLT--------LPFGAPRT
MAB_4544c|M.abscessus_ATCC_199 LVKGAAGAVRQVVSIPPGLLKYGRHAL-SDPQLV--------KPLSAPHT
Mflv_0349|M.gilvum_PYR-GCK LINVWFKTPYRITRLLEQTVRQQIAVRNIDNKPP--------RYFDAPKV
Mvan_2903|M.vanbaalenii_PYR-1 AIHTAVTQIGAVNQISLGASRKALSAVLGSHVEG-------SLPFVASHA
MLBr_01244|M.leprae_Br4923 LAGGVVGGLSGVASVAGRAILRPASTVSGVVGYVRSG---IRVLSQAAEP
: : . *
MUL_3162|M.ulcerans_Agy99 LLNHTAKSAARAYANMELPLAEVKAVAKATDTSINDVVMTIVDDALHHYL
MMAR_2598|M.marinum_M LLNHTAKSAARAYANMELPLAEVKAVAKATDTSINDVVMTIVDDALHHYL
Mb3115|M.bovis_AF2122/97 LFNNTAKSAARAYGNVELPLADVKALAKATGTSVNDVVMTVIDDALHHYL
Rv3088|M.tuberculosis_H37Rv LFNNTAKSAARAYGNVELPLADVKALAKATGTSVNDVVMTVIDDALHHYL
MAV_0355|M.avium_104 MLN-VKIGGARRCAAQSWPLERIKNVKNAAGVTVNDVVLAMCSGALRYYL
MSMEG_6322|M.smegmatis_MC2_155 MFN-VKIGGARRVAAQSWPLERLRRIKAVTGATINDIVLAMCAGALRAYL
TH_2030|M.thermoresistible__bu MFN-VRIGGARRVAAQSWPLQRIRRIRQAAGXTLNDVALAMCAGALRQYL
MAB_4544c|M.abscessus_ATCC_199 MLN-VSIGGARRFAAQTWSMARIKEAGKALGGTVNDVVLAMCGGALRTYL
Mflv_0349|M.gilvum_PYR-GCK RFN-GPISPHRSVAGASVPLDRVKAVKNAFDVKLNDVVLALVSGALRSYL
Mvan_2903|M.vanbaalenii_PYR-1 PTN-APPRQARGFATLSLPLQEMHRIGRRHGATLNDLAAAVIDHGLHSYL
MLBr_01244|M.leprae_Br4923 SPLLRQRSLATRTEAIEIQLSDLHKAAKAGDGSINDAYLAGLVGALRRYH
: :: . .:** : .*: *
MUL_3162|M.ulcerans_Agy99 DEHRAPADGPLVALMPMSMRS-QAG--AGNQVSAELIAMGAPKANLRQRL
MMAR_2598|M.marinum_M DEHRAPADRPLVALMPMSMRS-QAG--AGNQVSAELIAMGAPKANLRQRL
Mb3115|M.bovis_AF2122/97 AEHQASTDRPLVAFMPMSLRE-KSGEGGGNRVSAELVPMGAPKASPVERL
Rv3088|M.tuberculosis_H37Rv AEHQASTDRPLVAFMPMSLRE-KSGEGGGNRVSAELVPMGAPKASPVERL
MAV_0355|M.avium_104 LEQNALPDTPLIAMVPVSLRTEEEADAGGNLVGAILCNLATDSDDPAQRL
MSMEG_6322|M.smegmatis_MC2_155 AEQDALPDRPLIAMVPVSMRSEHEADAGGNMVGSILCSLGTDVEDPADRL
TH_2030|M.thermoresistible__bu LEHDALPATPLVAMVPVSLRSADESAGGGNRTGLVLCNLATDSDDPAERL
MAB_4544c|M.abscessus_ATCC_199 EEQNALPDKPLVAMCPVSIRAEGDQNAG-NSITALLANLATDKPDPLERF
Mflv_0349|M.gilvum_PYR-GCK KDRGELPAKSLVSQVPVSTRAQADDTVG-NQVNAMTVVLATDVADPAERI
Mvan_2903|M.vanbaalenii_PYR-1 REVGQDHPHEFIAMCPVSLREDGDSAVG-TRVSAIFVRLGKPEASMVDRL
MLBr_01244|M.leprae_Br4923 EALG-VSISTLPMAVPVNVRT-EADVVGSNRFVGVTLAAPLGTNDPAARM
: *:. * . . . *:
MUL_3162|M.ulcerans_Agy99 KQVSQATTAAKDKGDGMKSPSRQAYTLSL---FASLAMSDVLPGFG--KA
MMAR_2598|M.marinum_M KQVNQATTAAKDKGNGMKSPSRQAYTLSL---FASLAMSDVLPGFG--KA
Mb3115|M.bovis_AF2122/97 KEINAATTRAKDKGRGMQTTSRQAYALLL---LGSLTVADALPLLG--KL
Rv3088|M.tuberculosis_H37Rv KEINAATTRAKDKGRGMQTTSRQAYALLL---LGSLTVADALPLLG--KL
MAV_0355|M.avium_104 LTISESMRSNKKVFSQLPRFQALALSAAN---LSSLALA-AVPGWVSATS
MSMEG_6322|M.smegmatis_MC2_155 AVIRRSITDNKRVFSELPRLQALALSALL---IAPLGLTTAFPGFVDATA
TH_2030|M.thermoresistible__bu DRISSSMRSNKRVFSQLPRVQAMALSAAM---IAPLGLG-AVPGVVSSAP
MAB_4544c|M.abscessus_ATCC_199 SAIRDSVQAAKSVLSEMTPLQRMLVGALN---GAPVLTG-AVPGLVDRTA
Mflv_0349|M.gilvum_PYR-GCK KAIYSYTQGAKEMTKALTAHQIMGYTETTPPGLLALASRAYAASGIGSNI
Mvan_2903|M.vanbaalenii_PYR-1 RQVARSVAIAKEELGALSADAAMTYAVAL----VALAGAGASTHLDRVGH
MLBr_01244|M.leprae_Br4923 QKIRSQMTQRRDE-PAMNIIGSLAPLMTV--------LPASVLDFIVDSV
: : :
MUL_3162|M.ulcerans_Agy99 PSANLVISNMKGPAEQLYLAGAPMVSFGGLPILPPGAGLNVTVASVNEQL
MMAR_2598|M.marinum_M PSANLVISNMKGPAEQLYLAGAPMVSFGGLPILPPGAGLNVTVASVNEQL
Mb3115|M.bovis_AF2122/97 PSANVVISNMKGPTEQLYLAGAPLVAFSGLPIVPPGAGLNVTFASINTAL
Rv3088|M.tuberculosis_H37Rv PSANVVISNMKGPTEQLYLAGAPLVAFSGLPIVPPGAGLNVTFASINTAL
MAV_0355|M.avium_104 PPFNIVISNVPGPTAPLYYGGARLDGNYPLSIVLDGQALNITLASNAGNL
MSMEG_6322|M.smegmatis_MC2_155 PPFNLVISNVPGPKKPLYWRGARLAGNYPLSIALDGQALNMTVVSNAHNL
TH_2030|M.thermoresistible__bu PPFNLVISNVPGAPEPRYWMGARLAGNYPLSIVLDGQALNITLVTNADNL
MAB_4544c|M.abscessus_ATCC_199 PAFNVIISNVPGPRTDMFWNGFEMDGCYPASIPIDGVALNITCTSSGSSM
Mflv_0349|M.gilvum_PYR-GCK APMNVVISNVPGPTFPLYLGGARVEHLMPVGPLLFDVALNVTCFSYCGAV
Mvan_2903|M.vanbaalenii_PYR-1 PACNLVISNIPGGNATRYLNGAQLMGIFPVSALAASIGLNVTLTSYCDHM
MLBr_01244|M.leprae_Br4923 ASSDVNASNIPAYPGDTYFAGAKILRQYGIGPRP-GVAMMAVLMSRGGFC
.. :: **: . : * : . .: . :
MUL_3162|M.ulcerans_Agy99 CLGIGAAPEAVREPARLAQLIEQAFGQLQADIGRSAPAIAGHQADSA---
MMAR_2598|M.marinum_M CLGIGAAPEAVREPARLAQLIEQAFGQLQADIGRSAPAIAGHQADSA---
Mb3115|M.bovis_AF2122/97 CIAIGAAPEAVHEPSRLAELMQRAFTELQTEAGTTSPTTSKSRTP-----
Rv3088|M.tuberculosis_H37Rv CIAIGAAPEAVHEPSRLAELMQRAFTELQTEAGTTSPTTSKSRTP-----
MAV_0355|M.avium_104 DFGLVGCRRSVPHLQRLLMHLESSLKDLERAVGE----------------
MSMEG_6322|M.smegmatis_MC2_155 DFGLVGCRRSVPHLQRLLGHLETSLKDLETATGA----------------
TH_2030|M.thermoresistible__bu DFGLVGARGSVPHLQRLLGHLEDSLQQLERAVGG----------------
MAB_4544c|M.abscessus_ATCC_199 HFGLTGCRTSVPHLQRILAHLEDALTQLEESVA-----------------
Mflv_0349|M.gilvum_PYR-GCK DFGFITTPEIAADIVDLADQIEPALHDLEVAAGLVSDPTRPKPRKRGRR-
Mvan_2903|M.vanbaalenii_PYR-1 DFGFVANTAAISDVHALAEHTRRAFAECTAKTRVT---------------
MLBr_01244|M.leprae_Br4923 TVTVRYDRASVKSEALFARCLLEGFDEVLALAGDPTPHAVPASFAARSSG
. . : .: :
MUL_3162|M.ulcerans_Agy99 ---------
MMAR_2598|M.marinum_M ---------
Mb3115|M.bovis_AF2122/97 ---------
Rv3088|M.tuberculosis_H37Rv ---------
MAV_0355|M.avium_104 ---------
MSMEG_6322|M.smegmatis_MC2_155 ---------
TH_2030|M.thermoresistible__bu ---------
MAB_4544c|M.abscessus_ATCC_199 ---------
Mflv_0349|M.gilvum_PYR-GCK ---------
Mvan_2903|M.vanbaalenii_PYR-1 ---------
MLBr_01244|M.leprae_Br4923 SPAGWLSSS