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M. tuberculosis H37Rv Rv2947c (pks15)

annotation: PROBABLE POLYKETIDE SYNTHASE PKS15
coordinates: 3296350 - 3297840
length: 496

IEEQRTMSVEGADQQSEKLFHYLKKVAVELDETRARLREYEQRATEPVAVVGIGCRFPGGVDGPDGLWDV
VSAGRDVVSEFPTDRGWDVEGLYDPDPDAEGKTYTRWGAFLDDATGFDAGFFGIAPSEVLAMDPQQRLML
EVSWEALEHAGIDPLSLRGSATGVYTGIFAASYGNRDTGGLQGYGLTGTSISVASGRVSYVLGLQGPAVS
VDTACSSSLVAIHWAMSSLRSGECDLALAGGVTVMGLPSIFVGFSRQRGLAADGRCKAFAAAADGTGWGE
GAGVVVLERLSDARRLGHSVLAVVRGSAVNQDGASNGLTAPNGLAQQRVIQVALANAGLSAADVDVVEAH
GTATTLGDPIEAQALLSTYGQGGPAEQPLWVGSIKSNMGHTQAAAGVAGVIKMVQAMRHGVMPATLHVDE
PSPRVDWTSGAVSVLTEAREWSVDGRPRRAAVSSFGISGTNAHLILEEAPVPAPAEAPVEASESTGGRGR
RWCRG*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv2947cpks15-100% (496)PROBABLE POLYKETIDE SYNTHASE PKS15
M. tuberculosis H37RvRv1662pks80.073.78% (450) polyketide synthase pks8
M. tuberculosis H37RvRv1661pks70.071.71% (463) polyketide synthase pks7

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2971cpks10.099.59% (488) polyketide synthase PKS1
M. gilvum PYR-GCKMflv_0405-1e-13353.03% (445) beta-ketoacyl synthase
M. leprae Br4923MLBr_00135-0.090.52% (485) putative polyketide synthase
M. abscessus ATCC 19977MAB_0939-1e-13654.05% (444) polyketide synthase
M. marinum MMMAR_1762pks15/10.084.85% (482) polyketide synthase Pks15/1
M. avium 104MAV_3108-0.072.16% (467) erythronolide synthase, modules 3 and 4
M. smegmatis MC2 155MSMEG_0408-1e-13554.05% (444) type I modular polyketide synthase
M. thermoresistible (build 8)TH_4621-1e-11348.07% (441) PUTATIVE mycocerosic acid synthase
M. ulcerans Agy99MUL_2005pks15/10.084.65% (482) polyketide synthase Pks15/1
M. vanbaalenii PYR-1Mvan_1003-1e-13653.44% (451) beta-ketoacyl synthase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0405|M.gilvum_PYR-GCK          --------------MGSAAHQGE-SAHRFAIVGYAGRFPGARDAESFWEL
MAB_0939|M.abscessus_ATCC_1997      --------------MDSAENPIE-STPRFAIIGYAARFPGAADAEEFWDV
MSMEG_0408|M.smegmatis_MC2_155      --------------MVSAEHPIE-PTPSFAIIGYAARFPGAASAEEYWAL
Mvan_1003|M.vanbaalenii_PYR-1       MTDLQKRALQAIEVLRARVRELEGAGDGYAIVGYALRFPGAADADEFWDV
Rv2947c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_1762|M.marinum_M               --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          LADGRDAISEVPEDRWDVEAFFDPDPSTPGKVVTRRAGFVDDVSGFDAPF
MAB_0939|M.abscessus_ATCC_1997      LREGRDAISEVPADRWDAEEFFDPEPGAPGKVVTRRAGFVEDVTGFDAPF
MSMEG_0408|M.smegmatis_MC2_155      LRDGREAISDVPKDRWDIEEFFDPDPSTPGKVVTRRAGFVDDVTGFDAPF
Mvan_1003|M.vanbaalenii_PYR-1       LRGGRDAISEVPQDRWDADEFFDADPEAAGKMVTRRAGFVEDVAGFDAPF
Rv2947c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_1762|M.marinum_M               --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          FGMSTREVRLMDPQHRLLLETAWRAIEHSGTAPSELANTNTGVFVGLATH
MAB_0939|M.abscessus_ATCC_1997      FGMSTREVRLMDPQHRLLLETAWRAVEHSGIAPTDLAETNSGVFVGLATH
MSMEG_0408|M.smegmatis_MC2_155      FGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNTGVFVGLATH
Mvan_1003|M.vanbaalenii_PYR-1       FGVSAREAMFMDPQHRLLLETAWRAVEHSGTAPSALAGTRTGVFMGLSTH
Rv2947c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_1762|M.marinum_M               --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          DYLGMASDELSYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACS
MAB_0939|M.abscessus_ATCC_1997      DYLGMASDELTFPEIEAYMAIGTSNAAAAGRISYRLGLQGPSVAVDTACS
MSMEG_0408|M.smegmatis_MC2_155      DYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACS
Mvan_1003|M.vanbaalenii_PYR-1       DYLGMLTDNLTHDAIEAYLGTGTSPAAAIGRISYRLGLQGPAVAVDTACS
Rv2947c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_1762|M.marinum_M               --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          SSLVAIHQACQALRLGECDLALAGGANVILTPATMITFSNAHMLAPDGRC
MAB_0939|M.abscessus_ATCC_1997      SSLVAIHQACQALQLGECDLALAGGANVLLTPATMITFSHAHMLAPDGKC
MSMEG_0408|M.smegmatis_MC2_155      SSLVAIHQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRC
Mvan_1003|M.vanbaalenii_PYR-1       SSLVAVHQACQALRLAECDVALAGGVNVLLSPATMINFSRARMLAPDGRC
Rv2947c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_1762|M.marinum_M               --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          KTFDAAADGYVRGEGCGVIVIKRLEDAVRDGDRIRAVIRGSAINQDGASG
MAB_0939|M.abscessus_ATCC_1997      KTFDAAADGYVRGEGSGVIVIKRLEDAIRDGDRIRAVIRGSAINQDGASG
MSMEG_0408|M.smegmatis_MC2_155      KTFDAAADGYVRGEGCGVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASG
Mvan_1003|M.vanbaalenii_PYR-1       KTFDATADGYVRGEGCGVVVVKRLADAIRHGDRIRAVIRGSAVNQDGASG
Rv2947c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_1762|M.marinum_M               --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          GLTVPNGVAQQRVIGDALSRAGLAPGDVDYLEAHGTGTSLGDPIEAQAAG
MAB_0939|M.abscessus_ATCC_1997      GLTVPNGVAQQRVIADALKRAGVAPSEVGYLEAHGTGTSLGDPIEAQAAG
MSMEG_0408|M.smegmatis_MC2_155      GLTVPNGVAQQRVIADALKRAGLRPADVGYLEAHGTGTSLGDPIEAQAAG
Mvan_1003|M.vanbaalenii_PYR-1       GLTVPNGAAQQRVIADALTNAGLTAADVDYLEAHGTGTPLGDPIEVQAAG
Rv2947c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_1762|M.marinum_M               --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          AALGPGREPQRPLLIGSAKTNIGHLEAAAGIAGVIKVVLSLEHETLPKHL
MAB_0939|M.abscessus_ATCC_1997      AAYGIGRETNDPLLIGSAKTNIGHLEAAAGIAGVIKVILSLENELLPQHR
MSMEG_0408|M.smegmatis_MC2_155      EVLGAGRAPEEPLLIGSAKTNIGHLEAAAGIAGVIKVVMALENETLPKHL
Mvan_1003|M.vanbaalenii_PYR-1       AVLGVGREPDRPLLIGSVKTNIGHLEAASGIAGLLKVILSLEHQVLPKHL
Rv2947c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_1762|M.marinum_M               --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          NFENPSPHIPWDRLPVEVVKESIPWRRGQRGGRPRIAGVSSFGFAGTNAH
MAB_0939|M.abscessus_ATCC_1997      NFQNPSPHIPWDRLPVEVVREARPWGR---NGRPRIAGVSSFGFAGTNAH
MSMEG_0408|M.smegmatis_MC2_155      NFETPSPHIPWERLPIEVVRETVPWQR---NGKPRIAGVSSFGFAGTNAH
Mvan_1003|M.vanbaalenii_PYR-1       NFRSPSPHIPWNRLPVRIVDDPVPWTR---SGRSRVAGISSFGFSGTNAH
Rv2947c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_1762|M.marinum_M               --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          VILEEAPLAAEPAQES---VDDGRFTLLPLSARTPAALMAVADRYRDWLV
MAB_0939|M.abscessus_ATCC_1997      VILEEAPVVSRDAVEPPAPAGGRKFSILPLSARTPAALAQLADKYRAWLN
MSMEG_0408|M.smegmatis_MC2_155      VILEEAPAVGTPATTEP-VEDPRRYSVLPLSARTPEALVRLAGEYRDWLR
Mvan_1003|M.vanbaalenii_PYR-1       VLVEEAPRADRAGAAPQ-PAAPGGFGMLPLSARTPDALAATAHRLRTWLA
Rv2947c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_1762|M.marinum_M               --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          ANPDATLADLCFTAGTARSHLEHRAALVVNTREAALDLLGALADDRPAPG
MAB_0939|M.abscessus_ATCC_1997      AHPEAALADLCFTAGVGRAHLEHRAALVVNTREAAVELLSAVADDRPAPG
MSMEG_0408|M.smegmatis_MC2_155      AHPQARLADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPG
Mvan_1003|M.vanbaalenii_PYR-1       ANPDASWPDLCFTAAVGRSHLRHRAALVVDSRSSVEELLGALAEDRPGPG
Rv2947c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_1762|M.marinum_M               --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          LVRGESHDTPKTAWLFTGQGSQYPGMSRELFDTEPLFAETLRECAAAVDG
MAB_0939|M.abscessus_ATCC_1997      LGRGESHDTPKTAWLFTGQGSQYPGMARELFETEPVFADTLNRCAAAVAD
MSMEG_0408|M.smegmatis_MC2_155      LVRGESHEAPKTAWLFTGQGSQYPGMARELFDTEPVFAETVRKCAEAVAD
Mvan_1003|M.vanbaalenii_PYR-1       LARGECGDPPKTAWLFTGQGSQYPGMGRELFDTEPVYREVMTRCAEAVAD
Rv2947c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_1762|M.marinum_M               --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          MLEKPLLDVIFDTDGVLDTDSNETLRHTSYAQPALFAVEMGLARLWQSWG
MAB_0939|M.abscessus_ATCC_1997      VLEKPLLDVIFDVD---GPEAEETLRQTSYAQPALFAVEMGLARLWQSWG
MSMEG_0408|M.smegmatis_MC2_155      ILEKPLLDVIFDAD-ELDGDTESPLRHTTYAQPALFAVELGLARLWQSWG
Mvan_1003|M.vanbaalenii_PYR-1       VLERPLLDVVFDAD------GGEALRHTSYAQPALYAVEMGLARLWQSWG
Rv2947c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_1762|M.marinum_M               --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          FEPDVVLGHSVGQYAAACVAGVLSLRDGARLMAERGRLFGSLPSGGRMAA
MAB_0939|M.abscessus_ATCC_1997      FEPDVVLGHSVGQYSAACVAEVFSLEDGARLIAERGRLFSSLPAGGRMAA
MSMEG_0408|M.smegmatis_MC2_155      FEPDVVVGHSVGQYSAACVAGVFDVEDGARLIAERGRLFGSLPAGGRMAA
Mvan_1003|M.vanbaalenii_PYR-1       IEPDVVLGHSVGQYAAACVAGVMGLEDGAVLLAERGRLFGSLPEGGRMAA
Rv2947c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_1762|M.marinum_M               --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          VFAAAERVEALTDEYPALSVAAYNGANTVLSGPATDLERAVAGLVADGVR
MAB_0939|M.abscessus_ATCC_1997      VFTDAERAERLTDEFPSLSVAAYNGANTVLSGPAQDLEKAIAALVADGVR
MSMEG_0408|M.smegmatis_MC2_155      VFTAPERAERLTDEYPSLSVAAYNGANTVLSGPAKDLESAVATLVADGVR
Mvan_1003|M.vanbaalenii_PYR-1       VFAPADRVESCTVDSPLLSVAAYNGDNTVLSGPAGDLERAVAGFSAAGVR
Rv2947c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_1762|M.marinum_M               --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          CDWLETSHAFHSALLDPILDDFESYARGITFTAPQRILIDNRTGAALGRS
MAB_0939|M.abscessus_ATCC_1997      CDFLETSHAFHSALLDPILDEFEAYANQFNYKTPQRILIDNRTGTALGRS
MSMEG_0408|M.smegmatis_MC2_155      CDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALGRS
Mvan_1003|M.vanbaalenii_PYR-1       CDWLDTSHAFHSALLDPVLEEFESCADRFEFGTPQRTLVCNRSGEVLSRH
Rv2947c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_1762|M.marinum_M               --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          VTLDAAYWRRHARQPVEFAKSVHTLADMNCKLLVEIGPRPVLTAAALSAW
MAB_0939|M.abscessus_ATCC_1997      VKLDGAYWRRHARQPVEFAKSVRTLADMNCKVLLEIGPQPVLTAAALRAW
MSMEG_0408|M.smegmatis_MC2_155      TRLDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAW
Mvan_1003|M.vanbaalenii_PYR-1       ARLDGQYWRRHARQPVRFAESVRTLADLGCRLLMEIGPQPVLTAAAMRTW
Rv2947c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_1762|M.marinum_M               --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          PDPATSPRVIASLRRTTADQRQITEAVADAYVLGHLPRFAAFRRDGARVL
MAB_0939|M.abscessus_ATCC_1997      PDPATAPRAIASLRRNTADHRQITEAAADAYVLGHLPDFGAFQHAPARKL
MSMEG_0408|M.smegmatis_MC2_155      PDPATTPQVLASLRPTTADHRQITEAVAAAYAAGHLPDFRAFRQPDARKL
Mvan_1003|M.vanbaalenii_PYR-1       PGTVTAPRVAASMRRKGSDRRQITEALAQAYVAGHRPETAARQHGRGRLL
Rv2947c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_1762|M.marinum_M               --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          DLPTYPFEHRQYWFSDSRE---PVAAAPQR---GARTETVRLLEDGRIEE
MAB_0939|M.abscessus_ATCC_1997      DLPTYPFERRQYWFSDKRDGDNRDAGNRQQNNGGPRTEAVRLLEDGKIEE
MSMEG_0408|M.smegmatis_MC2_155      DLPTYPFEHRQFWFSDNRAIDRDTQTASAGSVTPHRTQAVRLLEDGQIEE
Mvan_1003|M.vanbaalenii_PYR-1       DLPTYPFQHRAYWFP--------QGQARTAPTDPVHTETVRFLDEERIDE
Rv2947c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_1762|M.marinum_M               --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          LAALLGGTVDDPFTFDVLNRLAAQHNQQRSTESIADDRYQIRWETAAEPP
MAB_0939|M.abscessus_ATCC_1997      LANLLGGVDGDQQTLNVLTKLAAQHNLQRTTQTIADDRYQFRWEKSPTPL
MSMEG_0408|M.smegmatis_MC2_155      LAALIDGETVDEQTLRVLNKLAARHNQQRSTHVDPDARYEIRWDAIASAA
Mvan_1003|M.vanbaalenii_PYR-1       LAALLDGPTGSAQTVDVLSKLAARHRQQRGAQSIADARYQIRWEKSEAPG
Rv2947c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_1762|M.marinum_M               --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          VGADAADGITWLLVGDDTDATRPLVDVLAARGHRYRILGLPKSGAEEHEL
MAB_0939|M.abscessus_ATCC_1997      SGSQAAGGVTWLLVADAAGAAQPLLDVLTARGQQHRVLALPVSDADEAEL
MSMEG_0408|M.smegmatis_MC2_155      ASTGAAA--DWILVGDDTAAVLEFADALTAGGHRHQIVALPGSDADEAQL
Mvan_1003|M.vanbaalenii_PYR-1       AARPTTEATTWLLVTHDSRAAQPIAEVLERRGHPYHIVGLPGSDADAAPA
Rv2947c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_1762|M.marinum_M               --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          ADTLRDAAADATDLRIVHVAALDAAESDTSMKSLLRMQHRVLGGTRRLFG
MAB_0939|M.abscessus_ATCC_1997      VEALRSAADEDSALRIVHVAALAGQGS-SSAQSLLRIQHQVLGGTRRLFR
MSMEG_0408|M.smegmatis_MC2_155      VDTLRAASAG--ELYVVHIAAGDGAAA--PMRDLLRVQHRTLGGLRRLFR
Mvan_1003|M.vanbaalenii_PYR-1       EEALRATVSQ-PRPHILYLAALEEPGG-SAAETLGWMQHRVLAAARRLFQ
Rv2947c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_1762|M.marinum_M               --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          AAVAAQLRSPMWLVTRGAQHVTDTDVVAPDQTCLWGFGRAASLEHPQIWG
MAB_0939|M.abscessus_ATCC_1997      AAAAAELRAPIWIVTRGAQHVIEGDTVAPEQSALWGFGRAAALELPQVWG
MSMEG_0408|M.smegmatis_MC2_155      AANDAELRSPIWLVTRDGQRVTDTDTVVPEQSCLWGFGRAAALELPHIWG
Mvan_1003|M.vanbaalenii_PYR-1       LAATAGARAPIWLITAGAQRITGDETVEPAQTSLWGFGRAAALEQPELWG
Rv2947c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_1762|M.marinum_M               --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          GLADLGGGTSDEWSRLLNRIAATHDPAVMEDQVAVRGSTSYVPRLVHRDT
MAB_0939|M.abscessus_ATCC_1997      GLADLSDAGTDEWAQFIGRVSVSGEASTREDQLALRGQAVHVPRLVRREE
MSMEG_0408|M.smegmatis_MC2_155      GLADLSGADT-EWPRLIARITSPRDG---EDQIALRGDAVYAPRLVRRTG
Mvan_1003|M.vanbaalenii_PYR-1       GLADVTTGDAEEWSALIDHIVAAPTS---EDQIAVRGREIHVARLTRCAE
Rv2947c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_1762|M.marinum_M               --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          LPSGKPLHLRADATYLVTGGLGSLGLEIAGYLAANGAGHLVLTSRRTPDE
MAB_0939|M.abscessus_ATCC_1997      LPSGKPLEVRSDATYLVTGGLGSIGLEIAGYLAGRGAKHLVLTSRREPGE
MSMEG_0408|M.smegmatis_MC2_155      EPSDTPLPVREDRTYLVTGGLGAIGLEVAGYLASHGAGHVVLTSRREPGD
Mvan_1003|M.vanbaalenii_PYR-1       KANAAALELRREATYLVTGGLGALGLEVAEFLASHGAGHLVLTGRRSASD
Rv2947c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_1762|M.marinum_M               --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          AAASRIEALRERHGCEVRVVTADVADAHAVARLLATVQAEMPPLAGIVHA
MAB_0939|M.abscessus_ATCC_1997      AARQRIDALAA-QGCEVRAVTADVADGHDVARLLAGIQAELPPLAGIVHA
MSMEG_0408|M.smegmatis_MC2_155      DARRRLDGLREQYACDVRVITADVADAHDVARLMTTVAAELPPLAGIVHA
Mvan_1003|M.vanbaalenii_PYR-1       TVRQRIDAMRERFDCQVLVATADVADRDDVARLFSTMRSELPPLAGIVHA
Rv2947c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_1762|M.marinum_M               --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          AGEIGTTPLADLDDAEVDRVFAGKVWGAWHLSEATSDLQ--LDFFISTSS
MAB_0939|M.abscessus_ATCC_1997      AGEIGTTPLSDLEDAEVDRVFAGKVWGAWHLSEAAAGLK--LDFFINTSS
MSMEG_0408|M.smegmatis_MC2_155      AGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEALTDLRTDLDFFVSTSS
Mvan_1003|M.vanbaalenii_PYR-1       AGEIGTSPLRTLDDAEMDRVFAGKVWGAVYLCEEVADMG--LDFFLATSS
Rv2947c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_1762|M.marinum_M               --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          IASVWGGFGQAAYGAANAFLDGLAWRLREQGVAGVSVNFGPWSAGMADAQ
MAB_0939|M.abscessus_ATCC_1997      IAAVWGGYGQTAYSAANAFLDGLAWRLREQGIAGTSVNFGPWSAGMADAE
MSMEG_0408|M.smegmatis_MC2_155      IASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPWAAGMADAE
Mvan_1003|M.vanbaalenii_PYR-1       IASVWGSHGQTAYGAANAFLDGLADSLRARGIPGISVNFGPWAAGMADAK
Rv2947c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_1762|M.marinum_M               --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          SRARLEQRGIKTLSPADALAGLSDAVISAAP---HPVVARVDWSRFLPLY
MAB_0939|M.abscessus_ATCC_1997      SRARLEQRGIKTLSPTDALAGLADVVAASGSNAVQGVIARIDWARFLPLY
MSMEG_0408|M.smegmatis_MC2_155      SRARLEQRGVRTLSPAEALAGMADVVAGPVQ----GVVAKIDWSRFLPLY
Mvan_1003|M.vanbaalenii_PYR-1       AREQLSRRGVKTLAPADALAGMADVIAASTA---HAVVARIDWATFLPVY
Rv2947c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_1762|M.marinum_M               --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          QQAGRRGFLAELERELPAAPAQQGPAVTASGRTPLVERLTTAPLQQRKRL
MAB_0939|M.abscessus_ATCC_1997      QQAGKRGFLAELDREVPSHLA--GVAGAQSGSTQLVERLANAPVQQRKKL
MSMEG_0408|M.smegmatis_MC2_155      QQAGRRAFLSELESELPAAATGAAAPATVPGKPPLVEQLTKAPVQQRKSL
Mvan_1003|M.vanbaalenii_PYR-1       QLQRRRAFLSQLEREVPDVPD--ASAPAPSGTTRFVEELTLAPVEQRRKL
Rv2947c|M.tuberculosis_H37Rv        -------------------------------MIEEQRTMSVEGADQQSEK
Mb2971c|M.bovis_AF2122/97           -------------------------------MIEEQRTMSVEGADQQSEK
MLBr_00135|M.leprae_Br4923          ------------------------------------MTASVEGADQKSEK
MMAR_1762|M.marinum_M               ------------------------------------MTTSGESADQQNDK
MUL_2005|M.ulcerans_Agy99           ------------------------------------MTTSGESADQQNDK
MAV_3108|M.avium_104                --------------------------------------------MPGTEQ
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          LTDYLRDAVAEVTRVDAAEIREDAGFFDLGMDSLMAVELRRRIETGVGKE
MAB_0939|M.abscessus_ATCC_1997      LTDYLRDAVAEVTRVDVSEIREDAGFFDLGMDSLMAVELRRRMEQGVGKE
MSMEG_0408|M.smegmatis_MC2_155      ITNYLRNAVAEVTRVDADEIRDEAGFFDLGMDSLMAVELRRRIEQGVGKD
Mvan_1003|M.vanbaalenii_PYR-1       VLEYLRAAVAEVTRVDAAEIRDEAGFFDLGMDSLMAIELRRRLEQGLGKE
Rv2947c|M.tuberculosis_H37Rv        LFHYLKKVAVELDETRARLREYEQ--------------------------
Mb2971c|M.bovis_AF2122/97           LFHYLKKVAVELDETRARLREYEQ--------------------------
MLBr_00135|M.leprae_Br4923          LISYLKKVVVELDETRARLREYEQ--------------------------
MMAR_1762|M.marinum_M               LFRYLKKVAVELDEARARLREYEQ--------------------------
MUL_2005|M.ulcerans_Agy99           LFRYLKKVAVELDEARARLREYEQ--------------------------
MAV_3108|M.avium_104                HLDYLKRLTADLRRTRRRVAELEG--------------------------
TH_4621|M.thermoresistible__bu      -----VNIVGDTP-------------------------------------
                                            . :                                       

Mflv_0405|M.gilvum_PYR-GCK          IPVTLVMDHPRLSDAADYLLGDVLGLTEAAT-APKAATVVSTAADEPIAI
MAB_0939|M.abscessus_ATCC_1997      IPVTLVMDHPRISDVADYLLGDVLGLAEQAKPAAQLASAVTGRTDEPIAI
MSMEG_0408|M.smegmatis_MC2_155      IPVTLVMDHPRLSDAADYLLVEVLGLGEQTN--VRQASTVTARTDDPIAV
Mvan_1003|M.vanbaalenii_PYR-1       LPVTLAMDHPHLSDAAEYVLGDVLGLSEHTV--AQPDTPSTVRTDDPIAI
Rv2947c|M.tuberculosis_H37Rv        ------------------------------------------RATEPVAV
Mb2971c|M.bovis_AF2122/97           ------------------------------------------RATEPVAV
MLBr_00135|M.leprae_Br4923          ------------------------------------------RATEPVAV
MMAR_1762|M.marinum_M               ------------------------------------------RATEPVAV
MUL_2005|M.ulcerans_Agy99           ------------------------------------------RATEPVAV
MAV_3108|M.avium_104                ------------------------------------------RLSEPVAV
TH_4621|M.thermoresistible__bu      --------------------------------------------VNAVAV
                                                                                 :.:*:

Mflv_0405|M.gilvum_PYR-GCK          VAVSCRFPG-APNPEAFWDLLSGGVDAIREVPEDR-FDIDEFYDPDPDAA
MAB_0939|M.abscessus_ATCC_1997      VAVSCRFPG-APDPEAFWDVLSGGVDAIREVPEDR-FDIDEFYDPDPEVA
MSMEG_0408|M.smegmatis_MC2_155      VAVSCRFPG-APDPESFWELLAGGVDAIREVPEDR-WDIDEFYDPDPDTP
Mvan_1003|M.vanbaalenii_PYR-1       VGMACRFPG-ADDTDAFWSVLAEGADLIREIPDDR-FDINEFYDPDPEAA
Rv2947c|M.tuberculosis_H37Rv        VGIGCRFPGGVDGPDGLWDVVSAGRDVVSEFPTDRGWDVEGLYDPDPDAE
Mb2971c|M.bovis_AF2122/97           VGIGCRFPGGVDGPDGLWDVVSAGRDVVSEFPTDRGWDVEGLYDPDPDAE
MLBr_00135|M.leprae_Br4923          VGIGCRFPGGVDSPDRLWDVVSECRDVVSEFPTDRGWDVDGLFDPDPDAE
MMAR_1762|M.marinum_M               VGIGCRFPGGADGPEGLWDLVSQGRDAVTEFPNDRGWDTEGLFDPDPDAE
MUL_2005|M.ulcerans_Agy99           VGIGCRFPGGADGPEGLWDLVSQGRDAVTEFPNDRGWDTEGLFDPDPDAE
MAV_3108|M.avium_104                VGMACRYAGGVDSPEALWDLVIEGRDTVSDFPVDRGWDVEGLYDPDPDAK
TH_4621|M.thermoresistible__bu      IGMACRLPGGIDSPQRLWEALLRGDDMVTEIPVDR-WDADDYFDPEPGVP
                                    :.:.** .*   ..: :*. :    * : :.* ** :* :  :**:* . 

Mflv_0405|M.gilvum_PYR-GCK          GKTYTRYGGFLDHIDEFDPEFFGLSPREAVWIEPQQRLMLETVWEGLERA
MAB_0939|M.abscessus_ATCC_1997      GKTYTRFGGFLDGIDGFDPEFFGISPREAVWIEPQQRLMLETVWEGLERA
MSMEG_0408|M.smegmatis_MC2_155      GKTYTRFGGFLDGIDGFDPEFFGISPREAVWIEPQQRLMLETVWEGLERA
Mvan_1003|M.vanbaalenii_PYR-1       GKIYSRYGGFLDGVDGFDPEFFGISPREAVWIDPQQRLVLETAWEGLERA
Rv2947c|M.tuberculosis_H37Rv        GKTYTRWGAFLDDATGFDAGFFGIAPSEVLAMDPQQRLMLEVSWEALEHA
Mb2971c|M.bovis_AF2122/97           GKTYTRWGAFLDDATGFDAGFFGIAPSEVLAMDPQQRLMLEVSWEALEHA
MLBr_00135|M.leprae_Br4923          GKTYTRWGAFLDDAAGFDAGFFGIAPSEVLAMDPQQRLMLEVSWEALEYA
MMAR_1762|M.marinum_M               GKTYTRWGAFVENATNFDAGFFGIPPSEVLAMDPQQRLMLEVSWEALEHA
MUL_2005|M.ulcerans_Agy99           GKTYTRWGAFVENATNFDAGFFGIPPSEVLAMDPQQRLMLEVSWEALEHA
MAV_3108|M.avium_104                GKMYTRQGSFLQHAGDFDAGFFGIGPSEALAMDPQQRIMLEICWEALERA
TH_4621|M.thermoresistible__bu      GRTVSRWGAFLDDVAGFDPEFFGISEREAISIDPQQRLLLETSWEAMEHA
                                    *:  :* *.*::    **. ***:   *.: ::****::**  **.:* *

Mflv_0405|M.gilvum_PYR-GCK          GYAPSALRGSRTGVFVGVAANEYAHLLSAESIDKIEPHFITGNALNAISG
MAB_0939|M.abscessus_ATCC_1997      GYSPAALRGSRTGIFAGVGANEYAHLLSSESIDKIEPYFITGNALNAISG
MSMEG_0408|M.smegmatis_MC2_155      GYAPSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISG
Mvan_1003|M.vanbaalenii_PYR-1       GYSAAALRGSRSGVYVGVGANEYSHLLSGGSLDGIEAQFITGNALNVIAG
Rv2947c|M.tuberculosis_H37Rv        GIDPLSLRGSATGVYTGIFAASYGNRDTG----GLQGYGLTGTSISVASG
Mb2971c|M.bovis_AF2122/97           GIDPLSLRGSATGVYTGIFAASYGNRDTG----GLQGYGLTGTSISVASG
MLBr_00135|M.leprae_Br4923          GIDPLSLRGSATGVFTGIFAPSYGSRDTG----GLQGYGLTGTAVSVASG
MMAR_1762|M.marinum_M               GIDPMSLRGSSTGVFTGIFAPSYGGKDVG----ALQGYGLTGSPVSVASG
MUL_2005|M.ulcerans_Agy99           GIDPMSLRGSSTGVFTGIFAPSYGGKDVG----ALQGYGLTGSPVSVASG
MAV_3108|M.avium_104                GIDPSALRGTATGVFAGVIHAGYGGEVKG----ELEGYGLTGSTLSVTSG
TH_4621|M.thermoresistible__bu      GLTPADVEGSSTGVFVGLSHDDYALLTSDAG-ALEEAYGFTGSAFSMASG
                                    *  .  :.*: :*::.*:    *.           :   :**....  :*

Mflv_0405|M.gilvum_PYR-GCK          RVAFALGLEGPAVAVDTACSSSLVAVHQATQALRSGDCDMALAGGVNVLL
MAB_0939|M.abscessus_ATCC_1997      RVAFALGFEGPAVAVDTACSSALVAVHQAVQALHSGDCDLALAGGVNVLL
MSMEG_0408|M.smegmatis_MC2_155      RVAFALGFEGPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLL
Mvan_1003|M.vanbaalenii_PYR-1       RVSFTLGLEGPAVAVDTACSSSLVAVHQACQGLQSGDCDLALAGGVNVLL
Rv2947c|M.tuberculosis_H37Rv        RVSYVLGLQGPAVSVDTACSSSLVAIHWAMSSLRSGECDLALAGGVTVMG
Mb2971c|M.bovis_AF2122/97           RVSYVLGLQGPAVSVDTACSSSLVAIHWAMSSLRSGECDLALAGGVTVMG
MLBr_00135|M.leprae_Br4923          RVSYVLGLEGPAVSVDTACSSSLVAIHWAMSSLRSGECDLALAGGVTVMG
MMAR_1762|M.marinum_M               RVAYVLGLEGPALSVDTACSSSLVAIHWAMASLRSGECDMALAGGVTVMG
MUL_2005|M.ulcerans_Agy99           RVAYVLGLEGPALSVDTACSSSLVAIHWAMASLRSGECDMALAGGVTVMG
MAV_3108|M.avium_104                RVSYVLGLEGPAVSVDTACSSSLVAMHLAAQSLRSGECDLALAGGVTVMA
TH_4621|M.thermoresistible__bu      RIAYRLGVHGPAVTVDTACSSSLLAVHMACRSLQVGESDLALAGGAMVML
                                    *::: **..***::*******:*:*:* *  .*: *:.*:*****. *: 

Mflv_0405|M.gilvum_PYR-GCK          SPVTVVAASRARMLSPVGRCKTFDASADGYVRSEGCGILVLKRLSDAVRD
MAB_0939|M.abscessus_ATCC_1997      SPVTVIAASRARMLSPVGRCKTFDASADGYVRSEGCGILVLKRLSDAERD
MSMEG_0408|M.smegmatis_MC2_155      SPVTVVAASRARMLSPVGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRD
Mvan_1003|M.vanbaalenii_PYR-1       SPATTIATSRARMLSPDGRCKTFDAAADGYVRGEGCGILVLKRLSDAVRD
Rv2947c|M.tuberculosis_H37Rv        LPSIFVGFSRQRGLAADGRCKAFAAAADGTGWGEGAGVVVLERLSDARRL
Mb2971c|M.bovis_AF2122/97           LPSIFVGFSRQRGLAADGRCKAFAAAADGTGWGEGAGVVVLERLSDARRL
MLBr_00135|M.leprae_Br4923          LPSIFVGFSRQRGLAADGRCKAFARAADGTGWGEGAGVVVLERLSDAQRL
MMAR_1762|M.marinum_M               LPSIFVGFSRQRGLAADGRCKAFAAAADGTGWGEGAGVLVLERLSDAQRN
MUL_2005|M.ulcerans_Agy99           LPSIFVGFSRQRGLAADGRCKAFAAAADGTGWGEGAGVLVLERLSDAQRN
MAV_3108|M.avium_104                TPAAFVEFSRQRALAPDGRCKVYAGAADGTSWSEGAGVLVLERLADARRL
TH_4621|M.thermoresistible__bu      EPRKYTSASGLGMLSPTGRCHAFDVAADGFVRSEGSVMLLLKRLPDALRD
                                     *      *    *:. ***:.:  :***   .**. :::*:**.** * 

Mflv_0405|M.gilvum_PYR-GCK          GDRVCAVIAGSAVNQDGASSGLTVPNGGAQQRLIGTVLARAGITGGEVDY
MAB_0939|M.abscessus_ATCC_1997      GDRVLAVIPGSAVNQDGASSGLTVPNGGAQQRLIGSVLARAGLVGGDVDY
MSMEG_0408|M.smegmatis_MC2_155      GDRVCAVIPASSVNQDGASSGLTVPNGGAQQRLIEATLARAGLSGADVDY
Mvan_1003|M.vanbaalenii_PYR-1       GDRIQAVIRGSAVNQDGASGGLTVPNGGAQQRVIAAALTRAGLSGSDIDY
Rv2947c|M.tuberculosis_H37Rv        GHSVLAVVRGSAVNQDGASNGLTAPNGLAQQRVIQVALANAGLSAADVDV
Mb2971c|M.bovis_AF2122/97           GHSVLAVVRGSAVNQDGASNGLTAPNGLAQQRVIQAALANAGLSAADVDV
MLBr_00135|M.leprae_Br4923          GHTVLAVVRGSAVNQDGASNGLTAPNGLAQQRVIQAALTNAGLSSADVDV
MMAR_1762|M.marinum_M               GHNVLAVVRGSAINQDGASNGLTAPNGLAQQRVIQAALANCGLTSADVDV
MUL_2005|M.ulcerans_Agy99           GHNVLAVVRGSAINQDGASNGLTAPNGLTQQRVIQAALANCGLTSADVDV
MAV_3108|M.avium_104                GHPVWAVLRGSAVNQDGASNGLTAPNGPSQQRVIRAALANAGLSAVDVDV
TH_4621|M.thermoresistible__bu      NDRILAVVRGTAANQDGRTENISTPSIQAQADVYRSALAVAGVDPATVGM
                                    .. : **: .:: **** : .::.*.  :*  :   .*: .*:    :. 

Mflv_0405|M.gilvum_PYR-GCK          LEAHGTGTPLGDPIEVQAAAAAYAGARDADRPLLMGSVKTNIGHTESASG
MAB_0939|M.abscessus_ATCC_1997      LEAHGTGTPLGDPIEVQAAAAAYGGSRDADRPLLMGSVKSNIGHTESASG
MSMEG_0408|M.smegmatis_MC2_155      LEAHGTGTPLGDPIEVQAAAAAYGAGRDADRPLLMGSVKTNIGHTESASG
Mvan_1003|M.vanbaalenii_PYR-1       LEAHGTGTSLGDPIEVQAAGAVLGAGRDPDRPLLMGSVKTNVGHLESASG
Rv2947c|M.tuberculosis_H37Rv        VEAHGTATTLGDPIEAQALLSTYGQGGPAEQPLWVGSIKSNMGHTQAAAG
Mb2971c|M.bovis_AF2122/97           VEAHGTATTLGDPIEAQALLSTYGQGRPAEQPLWVGSIKSNMGHTQAAAG
MLBr_00135|M.leprae_Br4923          VEAHGTATTLGDPIEAQALLATYGQGRPADQPLWVGSIKSNMGHTQAAAG
MMAR_1762|M.marinum_M               VEAHGTATTLGDPIEAEALLATYGQGRPTDQPLWVGSIKSNMGHTQAAAG
MUL_2005|M.ulcerans_Agy99           VEAHGTATTLGDPIEAEALLATYGQGRPTDQPLWVGSIKSNMGHTQAAAG
MAV_3108|M.avium_104                VEGHGTGTVLGDPIEAQALLATYGQDRPADRPLWLGSIKSNIGHTSAAAG
TH_4621|M.thermoresistible__bu      VEAHGTGTPVGDPIEYNSLTQVYGKTG----PCALTSVKTNFGHAESAAG
                                    :*.***.* :***** ::   . .       *  : *:*:*.** .:*:*

Mflv_0405|M.gilvum_PYR-GCK          AAGLIKVVLSLQHETLPQSLHFDTPSPHIPWDSLPVRVVDTAMPWQP-NG
MAB_0939|M.abscessus_ATCC_1997      AAGLIKVVLSLQNGVLPQSLHFDNPSPHIPWESLPVRVVDKAIPWQA-NG
MSMEG_0408|M.smegmatis_MC2_155      AAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQT-NG
Mvan_1003|M.vanbaalenii_PYR-1       VAGLIKVVLSLQHEMLPRHLHFKTPSPHIPWDRLAVRVVAEPTPWRA-DG
Rv2947c|M.tuberculosis_H37Rv        VAGVIKMVQAMRHGVMPATLHVDEPSPRVDWTSGAVSVLTEAREWSV-DG
Mb2971c|M.bovis_AF2122/97           VAGVIKMVQAMRHGVMPATLHVDEPSPRVDWTSGAVSVLTEAREWSV-DG
MLBr_00135|M.leprae_Br4923          VAGVIKMVQAMRHHVMPATLHVDEPSPRVDWTTGAVSVLTEARDWSV-EG
MMAR_1762|M.marinum_M               VAGVIKMVQAMRHGLMPASLHVDEPSKRVDWESGAVSVLAEARDWPD-AG
MUL_2005|M.ulcerans_Agy99           VAGVIKMVQAMRHGLMPASLHVDEPSKRVDWESGAVSVLAEARDWPD-AG
MAV_3108|M.avium_104                VAGVIKMVQALRHGVMPKTMHVDVPSPHVDWSAGAVSLLTDPRPWPE-HG
TH_4621|M.thermoresistible__bu      ALGMMKAILALQHGVVPQNLHFTRLPDEMAAIETNLFVPQATTLWPVREG
                                    . *::* : ::::  :*  :*.   . .:      : :   .  *    *

Mflv_0405|M.gilvum_PYR-GCK          RPRRAGVSSFGFTGTNAHVLIEEAPTDLAGPTEPTAPAEPVDEDAAADPA
MAB_0939|M.abscessus_ATCC_1997      RPRRAGVSSFGFTGTNAHVLIEEAPQPQATP----------DEDDASTPQ
MSMEG_0408|M.smegmatis_MC2_155      RVRRAGVSSFGFTGTNAHVLVEEAPPQLHTADAAP----VEPAATAEAGT
Mvan_1003|M.vanbaalenii_PYR-1       RPRRAGVSSFGFSGTNAHVVLEEPPAQSADLRQPPTDGKDGAAGLESATA
Rv2947c|M.tuberculosis_H37Rv        RPRRAAVSSFGISGTNAHLILEEAPVPAPAEAPVE-------ASESTGG-
Mb2971c|M.bovis_AF2122/97           RPRRAAVSSFGISGTNAHLILEEAPVPAPAEAPVE-------ASESTGGP
MLBr_00135|M.leprae_Br4923          RPRRAGVSSFGISGTNAHVILEEAPTPVEASYSTA-------DQQRLSVV
MMAR_1762|M.marinum_M               RPRRAGVSSFGISGTNAHVILEEAPAPEAVPDSES-------NKGEPSLP
MUL_2005|M.ulcerans_Agy99           RPRRAGVSSFGISGTNAHVILEEAPAPEAVPDSES-------NKGEPSLP
MAV_3108|M.avium_104                GPRRAGVSSFGISGTNAHVIVEQAPAAAETEAAPA-------SSTMPDAV
TH_4621|M.thermoresistible__bu      CPRRAAVSSYGMSGTNVHAVLEQAPEPVQRPEESA------------DTD
                                      ***.***:*::***.* ::*:.*                         

Mflv_0405|M.gilvum_PYR-GCK          PAPVEVLPLSARSPEALVALAQRYETWLTAH-PEADLADVCRTAGTGRSH
MAB_0939|M.abscessus_ATCC_1997      SAPVSVLPLSARSPEALAAVAQRYESWLAAH-PDVDLEDVCLTAGRGRSH
MSMEG_0408|M.smegmatis_MC2_155      DDSPQVLALSARSPEALVELARRYDDWLSAT-PGLDIADVCHTAGVGRSH
Mvan_1003|M.vanbaalenii_PYR-1       PEPAGVLPISARSPEALTALARRYESWLTAH-PDADIADVCYTAGAGRSH
Rv2947c|M.tuberculosis_H37Rv        --------------------RGRRWCRG----------------------
Mb2971c|M.bovis_AF2122/97           RPSMVPWVISARSAEALTAQAGRLMAHVQAN-PGLDPIDVGCSLAS-RSV
MLBr_00135|M.leprae_Br4923          P-----WVVSGRSTAALMAQASRLAFYVQAD-PEVDPVDVGCALAA-RSV
MMAR_1762|M.marinum_M               VVP---WVISARSAEALTAQAGRLLAHVQAD-PQSNPVDIGFSLAG-RSA
MUL_2005|M.ulcerans_Agy99           VVP---WVISARSAEALTAQAGRLLAHVQAD-PQSNPVDIGFSLAG-RSA
MAV_3108|M.avium_104                VP----WVVSARSAEALAGQARRLLDHVTAD-AQASPLDVGWSLVSTRAV
TH_4621|M.thermoresistible__bu      AAGPLVFALSSTSAEELRRTAGRLAEWVEAHTDEVVPADLAYTLARRRAH
                                                          *                           

Mflv_0405|M.gilvum_PYR-GCK          FEHRAALVVDSVESARIALTDLAQNRLRPGVVRGEHLNHPTTAWMFTGQG
MAB_0939|M.abscessus_ATCC_1997      FEHRAALVVDSIQTAREGLLELAQNRLRPGVVRGEHTNHPTTAWLFTGQG
MSMEG_0408|M.smegmatis_MC2_155      FEYRAALVVDSVERAREGLAALAEGRTPAGVVRGEHVHRPTTAWLFTGQG
Mvan_1003|M.vanbaalenii_PYR-1       FEHRAALVVDSVDGARDLLAGLAEDRLGPGAVRGVCGDPPKTAWLFTGQG
Rv2947c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           FEHRAVVVGASREQLIAGLAGLAAGEPGAGVAVGQPGSVGKTVVVFPGQG
MLBr_00135|M.leprae_Br4923          FEHRAVVVGESREQLIAGLAGLAVGESGAGVAIGQAAPLGKTVVVFPGQG
MMAR_1762|M.marinum_M               FEHRAVVVGADRQQLLTGLATLADGAPGAGVVTGQAGSVGKTAVVFPGQG
MUL_2005|M.ulcerans_Agy99           FEHRAVVVGADRQQLLTGLATLADGAPGAGVVTGQAGSVGKTAVVFPGQG
MAV_3108|M.avium_104                FEHRAVVVGRERGALATGLAGLASGRPGPATVVGRARSTGKTVLVFPGQG
TH_4621|M.thermoresistible__bu      RPVRTTVIADGVEALTAGLREVADGDAPYQPAVG--MDDKAPVWVFSGQG
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          SQYPGMARELFDTEPVFADTVTRCADAVADLLPRPLLDVMFAGGREAGVP
MAB_0939|M.abscessus_ATCC_1997      SQYPGMARELFDAEPVFAETVTRCAEAVKDIVTRPLLEVMFATDRETGGK
MSMEG_0408|M.smegmatis_MC2_155      SQYPGMARELFDTQPVFAQTVRQCAEAVADMLPRPLLDVLFATDRET---
Mvan_1003|M.vanbaalenii_PYR-1       SQYPGMARELFDTEPVFRDTVTRCAEAIGDTLPRPLLEVLFDTDGDN---
Rv2947c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           AQRIGMGRELYGELPVFAQAFDAVADELDRHLRLPLRDVIWGADADL---
MLBr_00135|M.leprae_Br4923          AQRIGMGRELCSQLPVFAEEFDAVTGELDRHMRLPLRDVVWGADAGL---
MMAR_1762|M.marinum_M               SQRIGMARELHDQLPVFAEAFDAVADELDRHLRIPLREVMWGSDAAL---
MUL_2005|M.ulcerans_Agy99           SQRIGMARELHDQLPVFAEAFDAVADELDRHLRIPLCEVMWGSDVAL---
MAV_3108|M.avium_104                SQTLGMGRQLYERFEVFAGALDEAVAVVDEHSRLSVREVMWGADPEL---
TH_4621|M.thermoresistible__bu      SQWAGMGAELLATEQVFAAKIAEIEPLVARESGFSVTEAMTASETVTG--
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          PTETLRHTSFAQPALFAVEMGLARLWQSWGIVPDVVLGHSVGQYAAACVA
MAB_0939|M.abscessus_ATCC_1997      AGEALRHTSFAQPALFAVEMGLARLWQSWGIEPDVVLGHSVGQYAAACVA
MSMEG_0408|M.smegmatis_MC2_155      -ADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACVA
Mvan_1003|M.vanbaalenii_PYR-1       -GQTLRHTSYAQPALFAIEMGLARLWQARGIEPDVVLGHSVGQYAAACVA
Rv2947c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           ----LDSTEFAQPALFAVEVASFAVLRDWGVLPDFVMGHSVGELAAAHAA
MLBr_00135|M.leprae_Br4923          ----LDSTEFAQPALFAVEVALFAVLQHWGLQPDFVMGHSIGELAAAYVA
MMAR_1762|M.marinum_M               ----LDSTEFAQPALFAVEVALFAALQRWGLQPDFVMGHSVGELSAAYVA
MUL_2005|M.ulcerans_Agy99           ----LDSTEFAQAALFAVEVALFAALQRWGLQPDFVMGHSVGELSAAYVA
MAV_3108|M.avium_104                ----LQSTEFAQPALFVFEVALAALWESLGVTPDVVMGHSVGEIAAACVA
TH_4621|M.thermoresistible__bu      -------IDRVQPTLFAIQVALAATMQSYGVRPGAVIGHSLGEVAAAVVA
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          GVFSLEDGARLMAERGRLFGSLPEGGRMVAVFADAKRVEQVAADFPR--V
MAB_0939|M.abscessus_ATCC_1997      GVFSIEDGARLIAERGRLFGGLPAGGRMVAVFSDAKHVEQIAGEFPR--V
MSMEG_0408|M.smegmatis_MC2_155      GVFSLDDGARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAGEFPR--V
Mvan_1003|M.vanbaalenii_PYR-1       GVFGLEDGARLVADRGRLFGGLPVGGRMVAVFTDAEVVEDFADEFPQ--V
Rv2947c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           GVLTLADAAMLVVARGRLMQALPAGGAMVAVAASEDEVEPLLGEG----V
MLBr_00135|M.leprae_Br4923          GVLAPADAAMLVVARGRLMQSMPAGGTMWAVAASEDEVVSLLGEG----V
MMAR_1762|M.marinum_M               GVLTLADAAMLVVARGRLMQALPAGGAMVAVAAAEDEVLPSLTDG----V
MUL_2005|M.ulcerans_Agy99           GVLTLVDAAMLVVARGRLMQALPAGGAMVAVAAAEDEVLPSLTDG----V
MAV_3108|M.avium_104                GVLSLRDAARLVAARGALMAALPPGGVMVAVTAGESQVGPLLGGG----V
TH_4621|M.thermoresistible__bu      GALSLEDGVKVICRRSRLCLRLAGAGAMAAIELPAQAVREFLAARGVDDV
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          SVGAYNGPN-TVLSGPGEDLEQIVGTFGEDGIRCTWLETSHAFHSELLDP
MAB_0939|M.abscessus_ATCC_1997      SVGAYNGPN-TVLSGPGEDLEQAVARFQEEGIRCTWLETSHAFHSELLDP
MSMEG_0408|M.smegmatis_MC2_155      SVGAYNGPN-TVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDP
Mvan_1003|M.vanbaalenii_PYR-1       SVAAYNGPN-TVLAGPASDLEQIVAGCSGEGIRTTWLDTSHAFHSALLDP
Rv2947c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           GIAAINAPESVVISGAQAAANAIADRFAAQGRRVHQLAVSHAFHSPLMEP
MLBr_00135|M.leprae_Br4923          GIAAINAPESVVISGPQAAVSAIADKFAAQGRRVHQLAVSHAFHSPLMEP
MMAR_1762|M.marinum_M               GIAAINAPKSVVISGAEAAVTAISDQFAQQGRRVHRLAVSHAFHSPLMEP
MUL_2005|M.ulcerans_Agy99           GIAAINAPKSVVISGAEAAVTAISDQFAQQGRRVHRLAVSHAFHSPLMEP
MAV_3108|M.avium_104                SIAAVNGPDAVVLSGEQEAVAAVADRLAGSGARVHRLAVSHAFHSALMEP
TH_4621|M.thermoresistible__bu      VLSVIASPESTVIGGATDTVRELVAAWEAQGVMAREVAVDVASHSPQVDP
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          VLDEFESYAAQLQFAAPTLPLVCNRTGAVLTGQT-SLDAQYWRRHSRQPV
MAB_0939|M.abscessus_ATCC_1997      ILDEFESYAAQVQFAAPTLPLVCNRTGAVLTAQT-PIDGQYWRRHSRQPV
MSMEG_0408|M.smegmatis_MC2_155      VLDEFEAYAAQFQFAAPTLPLVCNRTGAVLTGQT-PLDAQYWRRHSRQPV
Mvan_1003|M.vanbaalenii_PYR-1       VLDEFESCAARLAYAAPTRPLVCNRTGAVVTGPG-VIDAQYWRRHARQPV
Rv2947c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           MLEEFARVAARVQAREPQLGLVSNVTGELAGPD--FGSAQYWVDHVRRPV
MLBr_00135|M.leprae_Br4923          MLEEFVRVAAQVEVRKPQIGLVSNVTGELAGPD--FGSPQYWGEHVSRAV
MMAR_1762|M.marinum_M               MLEEFARIAAQVEAREPQIALVSNVTGELASADGGFGSAQYWVEHVRRAV
MUL_2005|M.ulcerans_Agy99           MLEEFARIAAQVEAREPQIALVSNVTGELASADGGFGSAQYWVEHVRRAV
MAV_3108|M.avium_104                MLDGFAAAAAGIEPRPPRIPLVSNLTGQLAGPG--YGTPQYWVDHVRRPV
TH_4621|M.thermoresistible__bu      ILDELEEILADLQPMTPTVPYYSATS--YDPREKPVCDADYWVDNLRHEV
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          QFAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHLAAPRAIASLRKG
MAB_0939|M.abscessus_ATCC_1997      QFAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHLAPPRAIVSLRKG
MSMEG_0408|M.smegmatis_MC2_155      QFAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHMAAPRAVASLRKG
Mvan_1003|M.vanbaalenii_PYR-1       QFAESVRTLADLGCSVLMEIGPQPFLIAAALRVWPESAATPRAIPSLRKG
Rv2947c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           RFADSARHLQTLGATHFIEAGPGSGLTGSIEQSLAP--AEAMVVSMLGKD
MLBr_00135|M.leprae_Br4923          RFVDSARHLQTLGATHFIESGPSSGLMGAIEQSLAP--AEAVVVSMMGKD
MMAR_1762|M.marinum_M               RFADSARQLHTLGVTHFVEVGPGSGLTGSIEQSLAP--AEAVVVSMLGKD
MUL_2005|M.ulcerans_Agy99           RFADSARQLHTLGVTHFVEVGPGSGLTGSIEQSLAP--AEAVVVSMLGKD
MAV_3108|M.avium_104                RFVDGVRLAESQGAGVFLEVGPGAALTSAVEQSLTS--DRAMSVVTMPKG
TH_4621|M.thermoresistible__bu      RFAAAVQAALEDGFRVFGELSPHPLLTRAVEQTARGLDMPVAALPAMRRE
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          VADRRQIADALAAAYIGGHKPDFAALHEQRG-VRLELPTYPFQRRRFWPK
MAB_0939|M.abscessus_ATCC_1997      VEDRRQIADALASAYVSGHRPNFAALQRHPR-RTVELPTYPFQRRRFWPK
MSMEG_0408|M.smegmatis_MC2_155      VADRRQIADALASAYVGGHRPDFAAVHRQPR-RPVELPTYPFQRRRFWPK
Mvan_1003|M.vanbaalenii_PYR-1       PDARRQLAEAVAAAYIAGHRLDFTGHDGGPH-RRLPLPTYPFQHRSYWPK
Rv2947c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           RPELASALGAAGQVFTTGVPVQWSAVFAGSGGRRVQLPTYAFQRRRFWET
MLBr_00135|M.leprae_Br4923          RPELASVLGAAGQLFATGMPVEWPAVFAGSSRRRVTLPTYAFQRRRFWET
MMAR_1762|M.marinum_M               RPEVASVLTAFGQLFSTGMSVDWPAVFAGSGATRVDLPTYAFQRRRFWEV
MUL_2005|M.ulcerans_Agy99           RPEVASVLTAFGQLFSTGMSVDWPAVFAGSGATRVDLPTYAFQRRRFWEV
MAV_3108|M.avium_104                RPEVDSLLTAAARLFTAGADVRWSAAFTGLHARRVDLPTYAFARRRFWLS
TH_4621|M.thermoresistible__bu      QEMPHGVRTMVGDLFAAGAAVDFAALYPSGRLVDAPLPTWTRRKLVLSRE
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          S---AGMAIDGRVGASAGSGILGSGKD-LASGD-SVYTSRLSVKTQPWLS
MAB_0939|M.abscessus_ATCC_1997      S---SGTAIEG--GGGLPSGILGRGED-LASGD-SVYISRLSVRSQPWLS
MSMEG_0408|M.smegmatis_MC2_155      A---SSIAVDG---GTAASGILGSGKD-LASGD-TIYTSRLSVKSQPWLA
Mvan_1003|M.vanbaalenii_PYR-1       T---AGIRSDG----SSGSGLLGSAQD-LASGD-IVHTSRLSVKTQPWLS
Rv2947c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           PGADGPADAAGLGLGATEHALLGAVVERPDSDE-VVLTGRLSLADQPWLA
MLBr_00135|M.leprae_Br4923          PGTDGTASVSGLGLGSTEHALLGAVVERPDSGG-VVLTGRLSLANQPWLA
MMAR_1762|M.marinum_M               PGADGPADATGLGLGGAEHALLGAVVERPDSGG-VVLTGRLALADQPWLA
MUL_2005|M.ulcerans_Agy99           PGADGPADATGLGLGGAEHALLGAVVERPDSGG-VVLTGRLALADQPWLA
MAV_3108|M.avium_104                GDAVGSANIASLGLAEAEHPLLGAVLDRPDSGG-VVLTGRLSTAAQPWLA
TH_4621|M.thermoresistible__bu      N----GEQQTRGGCTITVHPLLGTHVRLPEEPERHVWQADLGTGAQPWLA
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          DHVIYGTVVVPGATYAAMALAAVGTP--AHAKDVFFYEPIILPEKSSREV
MAB_0939|M.abscessus_ATCC_1997      DHVIYGTVVVPGATYAAMALAAVGTP--ARAKDVFFYEPIILPEKSSREV
MSMEG_0408|M.smegmatis_MC2_155      DHVIYGTVVVPGATYAAMALAAVGTP--ARLKDVFFYEPIILPEKASREV
Mvan_1003|M.vanbaalenii_PYR-1       DHVIYGTVVVPGATYAAMALAAMPTP--ARVQEVFFYEPIILGDKDSREV
Rv2947c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           DHVVNGVVLFPGAGFVELVIRAGDEVGCALIEELVLAAPLVMHPGVGVQV
MLBr_00135|M.leprae_Br4923          DHVIGGVVLFPGAGFVELVIRAGDEVGCAGVEELVLAAPLVLHPGSGVQV
MMAR_1762|M.marinum_M               DHVIGGVVLFPGAGFVELAIRAGDEVGCAVVEELVLAAPLVLHPGMGVQV
MUL_2005|M.ulcerans_Agy99           DHVIGGVVLFPGAGFVELAIRAGDEVGCAVVEELVLAAPLVLHPGMGVQV
MAV_3108|M.avium_104                DHAVAGTVLFPGAGFVELALRAGDEVGCPVVEELTLSAPLSLPAGGTVQL
TH_4621|M.thermoresistible__bu      DHQIHTVAALPGAAYCEMALAAAREVIDSDGVEVRDVRFEQMLLLDEQTE
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          QLTVHPSVDGE-SKFQVHSRPYGERGAEWALNAEGVVASGVGD---SPAA
MAB_0939|M.abscessus_ATCC_1997      QLTLHPLEDGSGSKFQVHSRPYGERDVDWSLNAEGTVVTGIGDDAEPAPE
MSMEG_0408|M.smegmatis_MC2_155      QLTLHPADGGSVLSFQIHSRPYGERGADWSLNAEGTVDTAGSD---PDAA
Mvan_1003|M.vanbaalenii_PYR-1       QLMLHRTDDADGWTFEVHSRPYGDRDADWSRNASGTVAAGVGD-----AA
Rv2947c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           QVVVG-AADESGHRAVSVYSRGDQSQG-WLLNAEGMLG---------VAA
MLBr_00135|M.leprae_Br4923          QVVVA-AADESSRRAVSVYSRGDQSHGGWLLNAEGLLE---------VDA
MMAR_1762|M.marinum_M               QVIVG-AADDSGNRALSVYSRGDQSED-WLLNAEGMLG---------VEA
MUL_2005|M.ulcerans_Agy99           QVIVG-TADDSGNRALSVYSRGDKSED-WLLNAEGMLG---------VEA
MAV_3108|M.avium_104                QVVVADAAGQPGSRSVAVYSR--VAQSEWTLHAEGVLS---------EAA
TH_4621|M.thermoresistible__bu      VSAVASAVEPGTLEFAVETAKDGEHERRATAVLGAADD----------TE
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          AGDLEDPVDEAIERLNRMRPQELFETFADLELAWGPTWSGSLKSLWLG--
MAB_0939|M.abscessus_ATCC_1997      AAEPAEPVDAAIERMERMRPMELFEIFADLELAWGPTWSGSLKSLWLG--
MSMEG_0408|M.smegmatis_MC2_155      ADEQSDPVDEVIERLERMRPQDLFETFADLELAWGPTWSGSLKSLWLG--
Mvan_1003|M.vanbaalenii_PYR-1       PDAAADPVDNAIERLTRTRPQQLFDAFADNDLAWGPAWCSSLRSLWVG--
Rv2947c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           AETPMDLSVWPPEGAESVDISDGYAQLAERGYAYGPAFQG-LVAIWRR--
MLBr_00135|M.leprae_Br4923          AEATVDLSLWPPEGAESVDISDAYPQLAERGYAYGPAFQG-LVAIWRR--
MMAR_1762|M.marinum_M               ASSGADLSVWPPEGAESVDISDGYAQLADRGYAYGPGFQG-LVGVWRR--
MUL_2005|M.ulcerans_Agy99           ASSGADLSVWPPEGAESVDISDGYAQLADRGYAYGPGFQG-LVGVWRR--
MAV_3108|M.avium_104                PAPAAELSVWPPADAEAVDVAGGYDDLAGRGYGYGPAFRG-LRAVWRR--
TH_4621|M.thermoresistible__bu      PPQAHDIDALLAEHPTRIEGDELRQWFDQRGVQFGPAFTGLTAARIPEGT
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          EGEAIGDILVGAELAEQLGTEPMHPVLMDLCTGVAFPAFPALLAAEQGVN
MAB_0939|M.abscessus_ATCC_1997      EGEAIGDVLVGEELAEQLGTEPMHPVLMDLCTGVAFPAFPALLAAEQGVN
MSMEG_0408|M.smegmatis_MC2_155      DGEAVGDILVGAELAEQLGSEPMHPVLMDLCTGVAFPAFPALLAAEQGVN
Mvan_1003|M.vanbaalenii_PYR-1       TGEAVGDIAVGAELGEHLGREPIHPVLLDLCTGIAGAALLAAAAQTDADP
Rv2947c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           GSELFAEVVAPGEAGVAVDRMGMHPAVLDAVL----HALGLAVEKTQAST
MLBr_00135|M.leprae_Br4923          GSELFAEVVAP--TGVVVDGMGMHPALLDAVL----HALGLAIENTQATT
MMAR_1762|M.marinum_M               DSELFAEVVAP--SGVAVDKMGMHPVVLDAVL----HALGLTAEQNPDSD
MUL_2005|M.ulcerans_Agy99           DSELFAEVVAP--SGVAVDKMGMHPVVLDAVL----HALGLTAEQNPDSD
MAV_3108|M.avium_104                GAETFAEVELPEQAGVSTGRFGIHPVLLDAAL----HALGVADKR----L
TH_4621|M.thermoresistible__bu      VTSVLAEVGLPGQIRSQQAPYGIHPALLDACF----QSVAAHPDVQGAGS
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          DLYLPLRYGQVSLQEKMPRRFYCRATWHEAPLDSETQVFDLEYLDRDGRH
MAB_0939|M.abscessus_ATCC_1997      DLFLPLRYGQVTLKEKMPRRFYCRARWHESPLDSETQVFDLDYLDRDGRH
MSMEG_0408|M.smegmatis_MC2_155      DLFLPLRYGQVTLAEKMPRRFYCRARWHRSALDSETQVFELEFVDLGGRA
Mvan_1003|M.vanbaalenii_PYR-1       ELFLPLRYGRVEVRERMPRRFYCRARWQTGGIDSETQVFDLDFLDHDGRN
Rv2947c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           ETRLPFCWRGVSLHAGGAGRVRARF------ASAGADAISVDVCDATGLP
MLBr_00135|M.leprae_Br4923          EMRLPFCWRGVSLHAGGAGRVRARF------TSAGADAIAVDIADSAGLP
MMAR_1762|M.marinum_M               ETKLPFCWRGVSLHAGGAGRVRARL------TMSGPDSISVEIADAAGLP
MUL_2005|M.ulcerans_Agy99           ETKLPFCWRGVSLHAGGAGRVRARL------TMSGPDSISVEIADAAGLP
MAV_3108|M.avium_104                ETVLPFSWQGVSLHAAGASRVRVRL------APAGAGAVSVELADASGVP
TH_4621|M.thermoresistible__bu      GLLLPLGVRRLQAFGPTRGARYCYAR--VTDADGSKAEADLDVLDEHGNV
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          LGGVREFTVKRAPREALLRGLGGDAT----RLLYTLGWHEVPVP----ES
MAB_0939|M.abscessus_ATCC_1997      LGGIREFTVKRAPREALLRGLGGDAT----RLLYTLGWHEVAVPPVAGEG
MSMEG_0408|M.smegmatis_MC2_155      LGGIREFTVKRAPREALLRGLGGDAT----RLLYTLGWHEVPPP------
Mvan_1003|M.vanbaalenii_PYR-1       LGGIREFTVKRAPREALLRGLGADAT----RLIYRVGWRETSPP---VRD
Rv2947c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           VLTVRSLVTRPITAEQLRAAVTAAGG-ASDQGPLEVVWSPISVV------
MLBr_00135|M.leprae_Br4923          VLTVRSLVTRAMTAEQLRTAVTAAGG-ALEQGPMDLVWSPIPLS------
MMAR_1762|M.marinum_M               VLTVGALVTRAMSAAQLRAAVAAAGGGAPDQGPLDVIWSPIPLS------
MUL_2005|M.ulcerans_Agy99           VLTVGALVTRAMSAAQLRAAVAEAGGGAPDQGPLDVIWSPIPLS------
MAV_3108|M.avium_104                VLSVRELVTRAVSAEQLAAAVAVRSG---SGELLDVAWSVIEPR------
TH_4621|M.thermoresistible__bu      LLRVQGLLMGGAAADGDDRDRVLGER------LLTIEWQRRDLP------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          GDGAAPQGTWLIGGFDELAVSVPGCIPADR----------------TNPE
MAB_0939|M.abscessus_ATCC_1997      EESAASIGTWLIAGFDELAAKVPGCIPLNRE---------------TDPE
MSMEG_0408|M.smegmatis_MC2_155      PSADDAVGTWLIAGFDELAAKVPGCVPIDRN---------------TDLQ
Mvan_1003|M.vanbaalenii_PYR-1       DGALGPSSTWLVAGLDALADDVPGSIRIGFDRIWDPDRDGRVVLDPADDE
Rv2947c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           SGGANGSAPPAPVSWADFCAGSDG--------------------------
MLBr_00135|M.leprae_Br4923          SDGHGG-GLPSVVSWADYCAGRGN--------------------------
MMAR_1762|M.marinum_M               GSGTNGSAQPAVVSWADFCAGGDGGA------------------------
MUL_2005|M.ulcerans_Agy99           GSGTNGSAQPAVVSWADFCAGGDGGA------------------------
MAV_3108|M.avium_104                NSLPDNPISEGVTVWEPAAVDGAG--------------------------
TH_4621|M.thermoresistible__bu      -EADSAAGKWLLVSTSATADVSATRLSDALKQAG----------AESTSM
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          SLRQLLTDAHGRGLPFSGVVWRAARSDGDES--DAEVAARLEAEIAELLG
MAB_0939|M.abscessus_ATCC_1997      LLGEVLVAAKERGVPFSGVVWRAAGPGATES--TTESAARLEGEIAHLLS
MSMEG_0408|M.smegmatis_MC2_155      VLGEVLSQAHARGAGFSGVVWRCATPGRKESGSASAESARLEAEITNLLS
Mvan_1003|M.vanbaalenii_PYR-1       HWRRLFALADERRAPVAGVVLGVTGRARPEE-PSADFAARLEAQIRDVLG
Rv2947c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           ---------------DASVVVWELESAGGQASS---VVGSVYAATHTALE
MLBr_00135|M.leprae_Br4923          ---------------DTGVVVWEFGSASAGAQAPVDSVAAVYSATHAALQ
MMAR_1762|M.marinum_M               -------------AGDAGVVVWEPNPAG------EDVVGSVYAATHAALE
MUL_2005|M.ulcerans_Agy99           -------------AGDAGVVVWEPNPAG------EDVVGPVYAATHAALE
MAV_3108|M.avium_104                -------------------------------------PAAVHAATHQALG
TH_4621|M.thermoresistible__bu      CWPQQADHADNVDRFRAGIADGVTGVVVLTGPKNGNPDDAAARRGSDYVR
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          AVHTVQ---GGEVKLPGGLWIVTERAVATESGEPVDPVQAALWGFGRTAI
MAB_0939|M.abscessus_ATCC_1997      AVHTVQNSAQNGVKLPGGLWIVTERAVATESGEPVDPVQAALWGFGRTTI
MSMEG_0408|M.smegmatis_MC2_155      AVHAAQ---GPSVKLPGGLWIVTEHGVACESGEPVDPVQAALWGFGRTTI
Mvan_1003|M.vanbaalenii_PYR-1       AVHSLS---ALGAKPAAGLWIVTERAVAAEAGEPVDPVQSALWGLGRTLI
Rv2947c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           VLQSWL-----GADRAATLVVLTHGGVGLAGEDISDLAAAAVWGMARSAQ
MLBr_00135|M.leprae_Br4923          VLQFWF-----GQDRAGTLVVLTRGAVGLVGEGISDLAAAAVWGMVRSAQ
MMAR_1762|M.marinum_M               VLQSWF-----DGDRAGTLVVLTHGAVAMPGENVSDLAGAAVWGIVRSAQ
MUL_2005|M.ulcerans_Agy99           VLQSWF-----DGDRAGTLVVLTHGAVAMPGENVSDLAGAAVWGIVRSAQ
MAV_3108|M.avium_104                VLQSRL-----AGEAGGVLVVSTRGAVGLPGEDVADLAGAAVWGLVRSAQ
TH_4621|M.thermoresistible__bu      HLVRITRELAEIDGDAPRLFVVTRGAQAVLPQDRPNLEQAGLRGLLRVIG
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          NEEPALRCRLVDCDGSPQAVQALAALLSTP-VDEPELAVRQGKLLASRLL
MAB_0939|M.abscessus_ATCC_1997      NEEPALRAKLVDGDGSPEAVQALARLLVTP-VDEPEIAVRQGKLLASRLL
MSMEG_0408|M.smegmatis_MC2_155      NEEPALHCRLVDCDGSSEAVDLLAALLAAPGIQEPEIAVRQGKLLASRLL
Mvan_1003|M.vanbaalenii_PYR-1       AEEPGLRCLLVDLDGSEDAGPALARLLGAP-GDEPELALRQGRLLVPRLL
Rv2947c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           AENP-GRIVLIDTDAAVDASVLAG-------VGEPQLLVRGGTVHAPRLS
MLBr_00135|M.leprae_Br4923          SEHS-GKIVLIDTDSAVDVAVLAD-------LGESQLLVRCNTVHAARLS
MMAR_1762|M.marinum_M               AENP-GRIVLVDADAAVEAAELVA-------VGEPQLVVRSGAAHAARLA
MUL_2005|M.ulcerans_Agy99           AENP-GRIVLVDADAAVEAAELVA-------VGEPQLVVRSGAAHAARLA
MAV_3108|M.avium_104                AEHP-GRVVLVDTDGSLDLATVIG-------CGEPQLVVRDGVAYRARLR
TH_4621|M.thermoresistible__bu      AEHPHLRTTQIDIADDADLDRVAVQLLGGG--AEDETAWRDGQWYTARLS
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          PWSRS----GHLTVPRG-GDYVLAPTERGAIDNLRLTDSEVPPPAE--GY
MAB_0939|M.abscessus_ATCC_1997      PWSRT----GHLTVPRG-SDYVLAPTERGAIDNLRITEKEVPAPDE--GY
MSMEG_0408|M.smegmatis_MC2_155      PWARS----GHLTLPRG-GDFVLAPTERGAIDNLRLTETDVPEPDE--GY
Mvan_1003|M.vanbaalenii_PYR-1       PWSRS----GQLAIPRG-TDYVLAPTERGVLDNLRVSETEVTAPPE--GH
Rv2947c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           PAP------ALLALPAAESAWRLAAGGGGTLEDLVIQPCPEVQAPLQAGQ
MLBr_00135|M.leprae_Br4923          PAP------QLLALPVGESMWRLAADGGGTLEDLVIQPCPEVQAPLQAGH
MMAR_1762|M.marinum_M               PAA------PLLAVPADESAWRLAAGGGGTLEDLVIEPCPEVQAPLAAGQ
MUL_2005|M.ulcerans_Agy99           PAA------PLLAVPADESAWRLAAGGGGTLEDLVIEPCPEVQAPLAAGQ
MAV_3108|M.avium_104                PAGRR----ALLELPGPPAVWRLAAGDAGTLEDLAVQEHP--AAELAPGQ
TH_4621|M.thermoresistible__bu      LSPLRPEERKQAVVDCERDGMRLEIRTPGDLETMELAAFDRVPPGP--GQ
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          VQVRVEAAGLNFRDVLNVLG---LYPGDPGPIGGDFAGTVTQLGEGVTGL
MAB_0939|M.abscessus_ATCC_1997      VQVRVEAAGLNFRDVLNVLG---LYPGDPGPIGGDFAGIVTQLGEGVTGV
MSMEG_0408|M.smegmatis_MC2_155      VQVRVEAAGLNFRDVLNVLG---LYPGDPGPIGGDFAGTVTQLGAGVSGL
Mvan_1003|M.vanbaalenii_PYR-1       VQVRVEAAGLNFRDVLNALG---LYPGDPGPIGGELAGVVTAPGPDVDGF
Rv2947c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           VRVAVAAVGVNFRDVVAALG---MYPGQAPPLGAEGAGVVLETGPEVTDL
MLBr_00135|M.leprae_Br4923          MRVAVAAVGVNFRDVVAALG---MYPGQAPPLGAEGAGVVIEIGPEVTGV
MMAR_1762|M.marinum_M               VRVAVRAVGVNFRDVVAALG---MYPGEAPPLGAEGAGVVLEVGPQVSGV
MUL_2005|M.ulcerans_Agy99           VRVAVRAVGVNFRDVVAALG---MYPGAAPPLGAEGAGVVLEVGPQVSGV
MAV_3108|M.avium_104                VRVRVAAAGVNFRDVLVALG---MYPG-AAQLGAEGAGVVTEVGAGVTDV
TH_4621|M.thermoresistible__bu      IEVAVTASSINFADVLIAFGRYPTFDGRRPQLGTDFAGVVTAVGPDVTSH
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          DVGQRVYGS-MQGAFASRFNVPGQFLAPIPDGVSAVEAATIPAAALTVRL
MAB_0939|M.abscessus_ATCC_1997      EVGQRVYGS-MQGAFGSRFNVPAQFLAPIPDGISGVEAATIPAAALTVRL
MSMEG_0408|M.smegmatis_MC2_155      EIGQRVYGS-MQGAFASRFNVPAQFLAPIPDGIGAVEAATIPAAALTVRL
Mvan_1003|M.vanbaalenii_PYR-1       DVGQRVFGF-AVGAFASRVNVPVQFLAPVPEGISAVAAATTPAAVLTAGL
Rv2947c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           AVGDAVMG--FLGGAGPLAVVDQQLVTRVPQGWSFAQAAAVPVVFLTAWY
MLBr_00135|M.leprae_Br4923          AVGDAVMG--FLGGAGPLAVVHQQLITQMPQGWSLAEAAAVPVVFLTALF
MMAR_1762|M.marinum_M               AVGDSVMG--FLGGAGPLSVVDQQLITRMPQGWSFAQAAAVPVVFLTALF
MUL_2005|M.ulcerans_Agy99           AVGDSVMG--FLGGAGPLSVVDQQLITRMPQGWSFAQAAAVPVVFLTALF
MAV_3108|M.avium_104                AVGDAVMG--IFGLVGSEAAVDRRLVTRVPPGWSMAQAAGIPVVFLTAYY
TH_4621|M.thermoresistible__bu      RVGDRVGGLSPNGCWSTFVTCDADLAVPLPDGLTEGQAAAVSTAHATAWY
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          SFD-WAQVKSGDKVLIHAASGGVGLAAVQMAQQCGAEVYATAST-FKRAT
MAB_0939|M.abscessus_ATCC_1997      SFD-WAQLKPGDKVLIHAASGGVGLAAIQMAQQFGAEVFATAST-FKRAT
MSMEG_0408|M.smegmatis_MC2_155      AFD-WAQLKPGDKVLIHAASGGVGLAAIQMAQQSGAEVFATAST-FKRST
Mvan_1003|M.vanbaalenii_PYR-1       AFD-WAALRAGDRVLIHAASGGVGLAAVQLARQRGATVFATASG-YKRPM
Rv2947c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           GLADLAEIKAGESVLIHAGTGGVGMAAVQLARQWGVEVFVTASR-GKWDT
MLBr_00135|M.leprae_Br4923          GLADLAGIRAGESVLIHAGTGGVGMAAVQFARHWGVEIFVTASR-GKWDT
MMAR_1762|M.marinum_M               GLQDLAKIQPGESVLIHAGTGGVGMAAVQLARHWGVEIFVTASR-GKWDT
MUL_2005|M.ulcerans_Agy99           GLQDLAKIQPGESVLIHAGTGGVGMAAVQLARHWGVEIFVTASR-GKWDT
MAV_3108|M.avium_104                GLSVLAGLRAGQRVLVHAATGGVGMAAVQLARHWGAEVFATASR-GKWDT
TH_4621|M.thermoresistible__bu      GLHDLARLGAGEKVLIHSATGGVGLAAIAIARSVGAQIYATAGSPARRDL
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          LRKLGVK--HVYDSRTTDFAEQILADTDGAGVDVVLNSLTSEGFIEATLR
MAB_0939|M.abscessus_ATCC_1997      LRKLGVK--YVYDSRTTDFADQILADTDGAGVDVVLNSLTSEGFIEATLR
MSMEG_0408|M.smegmatis_MC2_155      LRRLGVK--YVYDSRTTDFADQILADTNGAGVDVVLNSLTSAGFVEATLK
Mvan_1003|M.vanbaalenii_PYR-1       LRAMGVD--HVYDSRTTDFADQILADTDGAGVDVVLNSLTNDGFVAATVR
Rv2947c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           LRAMGFDDDHIGDSRTCEFEEKFLAVTEGRGVDVVLDSLAGE-FVDASLR
MLBr_00135|M.leprae_Br4923          LRDMGFDDDHIGDSRTLEFEEKFLAVTDGRGVDVVLDSLAGD-FVDASLR
MMAR_1762|M.marinum_M               LRAMGFDDDHIGDSRTLDFEEKFLAVTDGRGVDVVLDSLAGD-FVDASLR
MUL_2005|M.ulcerans_Agy99           LRAMGFDDDHIGDSRTLDFEEKFLAVTDGRGVDVVLDSLAGD-FVDASLR
MAV_3108|M.avium_104                LRAMGFDDAHIADSRTLDFEQKFGAAPG--GMDVVLNSLAGE-FNDASLR
TH_4621|M.thermoresistible__bu      LRDMGIE--HVYDSRSTAFADEIRRDTDGYGVDVVLNSLPGAAQRAG-LE
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          ATAQHGRFAEIAKRDIWTVEQMAAA--RPDLAYEIVALDTVMFTEPDRIR
MAB_0939|M.abscessus_ATCC_1997      ATAKNGRFAEIAKRDIWTTEQMAQS--RPDIAYEIVALDTVMFQEPDRIR
MSMEG_0408|M.smegmatis_MC2_155      ATAQGGRFAEIAKRDIWSHEQMAEA--RPDIAYEIVALDTVMFTEPDRIR
Mvan_1003|M.vanbaalenii_PYR-1       ATARNGRFAEIAKRDIWSPEQMAAA--RPDIDYEVLALDAVMQQDPDRIQ
Rv2947c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           LLVRGGRFLEMGKTDIRDAQEIAAN--YPGVQYRAFDLSEAG---PARMQ
MLBr_00135|M.leprae_Br4923          LLVRGGRFLEMGKTDIRDAQEIAAN--YPGVQYRAFDLSEAG---PVRMQ
MMAR_1762|M.marinum_M               LLVRGGRFLEMGKTDIRDADKIAAN--YPGVWYRAFDLSEAG---PVRMQ
MUL_2005|M.ulcerans_Agy99           LLVRGGRFLEMGKTDIRDADKIAAN--YPGVWYRAFDLSEAG---PVRMQ
MAV_3108|M.avium_104                LLGPGGRFIEMGKTDLRDPDVVARA--HPGVRYRAFDLMEAG---PDRIA
TH_4621|M.thermoresistible__bu      LLSFGGRFIEIGKRDIYGDTRLGLFPFRRNLAFHGVDLGLMADSHPHKIR
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          DLLTEVSAGLRDGAWTPLPAEVYPLTEARAAFRRMQQARHIGKIVVQIPN
MAB_0939|M.abscessus_ATCC_1997      VLLTEVSEGLAKGEWTPLPAEIYPLTEARTAFRRMQQARHIGKIVCQMPN
MSMEG_0408|M.smegmatis_MC2_155      DLLTEVSDGMARGEWTPLPAEIYPITEARSAFRRMQQARHIGKIVLQVPK
Mvan_1003|M.vanbaalenii_PYR-1       LLLADLADSLARGETAPLPFEAYPLAEATTAFRRMQQARHTGKIILQMPK
Rv2947c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           EMLAEVRELFDTRELHRLPVTTWDVRCAPAAFRFMSQARHIGKVVLTMPS
MLBr_00135|M.leprae_Br4923          EMLCEVRELFDTQVLHRLPVTSWDVRCAPAAFRFMSQARHIGKVVLTMPS
MMAR_1762|M.marinum_M               EMLAEVRELFDTAVLHRLPVTTWDVRCAPAAFRFMSQARHIGKVVLTMPS
MUL_2005|M.ulcerans_Agy99           EMLAEVRELFDTAVLHRLPVTTWDVRCAPAAFRFMSQARHIGKVVLTMPS
MAV_3108|M.avium_104                AMLAEVMELFAAGALTPLPVKAFDARCAADAYRFVSAARHIGKVVLTMPD
TH_4621|M.thermoresistible__bu      ELLETVYRLTADGVLPMPQSTHYPLAEAATAIRVMSAAEHVGKLVLDVPH
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          P-----------LQP-QPDRSYLITGGLGAIG-LHTAGYLAQLGAGDIVL
MAB_0939|M.abscessus_ATCC_1997      P-----------LAP-RPDRTYLITGGLGAIG-LHTAAYLAQLGAGDIVL
MSMEG_0408|M.smegmatis_MC2_155      P-----------LQP-QQDRSYLITGGLGAIG-LHTAAYLAQLGAGDIVL
Mvan_1003|M.vanbaalenii_PYR-1       P-----------LQP-HGDRSYLITGGLGALG-LHAAAYLAQLGAGDIVL
Rv2947c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           A-----------LADRLADGTVVITGATGAVGGVLARHLVGAYGVRHLVL
MLBr_00135|M.leprae_Br4923          A-----------LADGLAEGTVLITGASGAIGGVLARHMVSAYGVRHLVL
MMAR_1762|M.marinum_M               A-----------LADGLADATVLITGATGAVGAVLARHMLDAYGVRHLVL
MUL_2005|M.ulcerans_Agy99           A-----------LADGLADATVLITGATGAVGAVLARHMLDGYGVRHLVL
MAV_3108|M.avium_104                G-----------PAG-LSGGTALITGATGMAGAALARHLVARHRVPHLML
TH_4621|M.thermoresistible__bu      TGRADVVVPPEQASPFRSDGAYIVTGGMGGLG-LYLAGEMAAAGAGCIVL
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          TSRRAPDAAAQQAIADIADRTKARLHVFTADVGVEADVAALLERIRAELP
MAB_0939|M.abscessus_ATCC_1997      TSRRAPDTDAQRVIGEITERSKTRIHVFTADVGAESEVAGLLERIRAELP
MSMEG_0408|M.smegmatis_MC2_155      TSRRDPDESAQRAIDEITERHKCRIHTYAADVGDEAQVADLLARIRAELP
Mvan_1003|M.vanbaalenii_PYR-1       TGRRMPDAATERAISEIAERYHCRIHTFAADVGDESAVRDLLERIRTELP
Rv2947c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           ASRRGDRAEGAAELAADLTEAGAKGQVVACDVADRAAVAGLFAQLSREYP
MLBr_00135|M.leprae_Br4923          ASRRGDRAEGAVELAAELVGAGAKIQVVACDVADNDAVRGLFAQLSREFP
MMAR_1762|M.marinum_M               ASRRGDRAEGAAELAAELSEAGANVQVVACDVADRDAVEAMLARLSGEYP
MUL_2005|M.ulcerans_Agy99           ASRRGDRAEGAAELAAELSEAGANVQVVACDVADRDAVEAMLARLSGEYP
MAV_3108|M.avium_104                VGRRGEAAPGMAELAAELRGAGASVSVLSCDVGDRDAVAAMLAQVPARYP
TH_4621|M.thermoresistible__bu      NGRSAPSGEALRTIEQLRAAGTEVIVECGXXX---------------RGQ
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          PLAGVAHLAGVLDDALLSQQSVERFRTALAPKAFGAVHLDRLTRVDDLDF
MAB_0939|M.abscessus_ATCC_1997      PLAGVAHLAGVLDDALLGQQSVERFRTTLAPKAFGAEYLDRLTKGDDLDF
MSMEG_0408|M.smegmatis_MC2_155      PLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHLDRLTRDDDLDF
Mvan_1003|M.vanbaalenii_PYR-1       PLAGVAHLAGVLDDALLPQQSPERFRTTLAPKAFGAWHLHRLTRDTELEF
Rv2947c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           PVRGVIHAAGVLDDAVITSLTPDRIDTVLRAKVDAAWNLHQATSDLDLSM
MLBr_00135|M.leprae_Br4923          PVRGVIHAAGVLDDGAITSLTPDRVDTVLRAKVDAAWNLHEATRDLDLLM
MMAR_1762|M.marinum_M               PVRGVIHAAGVLDDAVISSLTPERIDTVLRAKVDAAWNLHEATLDLDLSM
MUL_2005|M.ulcerans_Agy99           PVRGVIHAAGVLDDAVISSLTPERIDTVLRAKVDAAWNLHEATLDLDLSM
MAV_3108|M.avium_104                -LRSVFHAAGVLDDAVIASLTPARIDTVLRAKVDGAWNLHELTKDLDLSA
TH_4621|M.thermoresistible__bu      PVEVAVPTELRHADEHPDRRGAQLCDEFARGEQGAQRNQHRTDAGEGQRD
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          FLVSSSVSSLFGSPGQSNYATANAFLDGLVAQRRAQGLPATGVNFGPWAR
MAB_0939|M.abscessus_ATCC_1997      FIVSSSVSSLFGSPGQSNYATANALLDGLIAQRRAQGLPATGINFGPWGQ
MSMEG_0408|M.smegmatis_MC2_155      FIVSSSVSSLFGSPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQ
Mvan_1003|M.vanbaalenii_PYR-1       FIVYSSGSSVLGSPGQANYATANAVLDGLVAHRKARGLPATGVNWGPWAQ
Rv2947c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           FVLCSSIAATVGSPGQGNYSAANAFLDGLAAHRQAAGLAGISLAWGLWEQ
MLBr_00135|M.leprae_Br4923          FVLCSSIAATVGSPGQGNYSAANAFLDGLAAYRQAAGLAGTSLAWGLWEQ
MMAR_1762|M.marinum_M               FVLCSSIAATVGSPGQGNYSAANSFLDGLAAHRQAAGLAGISVAWGLWEQ
MUL_2005|M.ulcerans_Agy99           FVLCSSIAATVGSPGQGNYSAANSFLDGLAAHRQAAGLAGISVAWGLWEQ
MAV_3108|M.avium_104                FVVFSSMAGIVGAPGQGNYAAANSFLDALAIHRHAHGLPALSVAWGMWEE
TH_4621|M.thermoresistible__bu      AHPPGAVGHDQPDPG---------ALSDTGLDERGGQFPGVGVQIPVADP
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          -GGMAS--SEAAAANISAQGLIPLEPSAALTAMAEVVANGTAQATVLKAN
MAB_0939|M.abscessus_ATCC_1997      -GGMAS--SEAATANISAQGLIPLDPSAALAALAEVVANGTGQATILKAN
MSMEG_0408|M.smegmatis_MC2_155      -GGMAS--SEAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKAN
Mvan_1003|M.vanbaalenii_PYR-1       -GGMAT--SDAARANLGAQGLIPLEPTAALNALGEIVAHGIASAVVLKAN
Rv2947c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           PGGMTAHLSSRDLARMSRSGLAPMSPAEAVELFDAALAIDHPLAVATLLD
MLBr_00135|M.leprae_Br4923          PGGMNAHLSSRDLARISRSGLAPMNPAQALELFDAALVIDHPFMVTALLD
MMAR_1762|M.marinum_M               SGGMAAHLSSRDLARMSRSGLAPMNPEQAVGLLDAVLAINHPLMVATLLD
MUL_2005|M.ulcerans_Agy99           SGGMAAHLSSRDLARMSRSGLAPMNPEQAVGLLDAVLAINHPLMVATLLD
MAV_3108|M.avium_104                PSAMTAHLEERDKARMSRAGLSALSTRQALDLLDDALLGEQPLVVGTRLD
TH_4621|M.thermoresistible__bu      GVGIDHRGAVRVDSGVP----------AQQGVDGEVVRHRTLSSVRSGRS
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          -WQRAAKVLGSSRPPILDLVLPSAVG--------EITGDSELLKQLQEIP
MAB_0939|M.abscessus_ATCC_1997      -WQRAAKVLGSSRPPILDLVLPSAVG--------EVTGDSELLKQLMEIP
MSMEG_0408|M.smegmatis_MC2_155      -WQRAAKVLGSARPPILDLVLPSAAG--------EATGDSELLKQLMEIP
Mvan_1003|M.vanbaalenii_PYR-1       -WQRAAKLLGATRPPILDHVLPSAVA--------AGPGDSALLKQLQDVP
Rv2947c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           RAALDARAQAGALPALFSGLARRPRRRQIDDTGDATSSKSALAQRLHGLA
MLBr_00135|M.leprae_Br4923          RAALDAQAQAGALPPLFSRLVRRSRRRQIEDPGDATQSKLALVQRLQGLA
MMAR_1762|M.marinum_M               RPALEARAQAGGLPPLFAGVVRRPRRRQIEDTGDAAQSKSALAERLNGLS
MUL_2005|M.ulcerans_Agy99           RPALEARAQAGGLPPLFAGVVRRPRRRQIEDTGDAAQSKSALAERLNGLS
MAV_3108|M.avium_104                RAALAQHRAA--LPPLLSELAGRPARRMLEHT--DMVSLTGLRARLAGMN
TH_4621|M.thermoresistible__bu      SRWTAPGSRCGSGRRYGGESCRRTTG--------PAAGAAARRGRTRRRR
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          VPQRAGFVTEFLQKEVQNFLRLAQPP--AATSRFLDLGTDSLMAIELRNR
MAB_0939|M.abscessus_ATCC_1997      VPQRAGFVTEFLQREVQNFLRLAQPP--AATSRFLDLGTDSLMAIELRNR
MSMEG_0408|M.smegmatis_MC2_155      IPQRAGFVTEFLQREVQNFLRLASPP--AASSRFLDLGTDSLMAIELRNR
Mvan_1003|M.vanbaalenii_PYR-1       EAQRGSFVTEHLQRELQQILGLAQPP--AATGRFLELGMDSLMAVELRNR
Rv2947c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           ADEQLELLVGLVCLQAAAVLGRPSAEDVDPDTEFGDLGFDSLTAVELRNR
MLBr_00135|M.leprae_Br4923          ANRQLELLVGVVCLQAAAVLGRPSPEDIDPNTKFQDLGFDSLTAVELRNR
MMAR_1762|M.marinum_M               AGERQDALVGLVCLQAAAVLGRPSPEDIDPEAGFQDLGFDSLTAVELRNR
MUL_2005|M.ulcerans_Agy99           AGERQDALVGLVCLQAAAVLGRPSPEDIDPEAGFQDLGFDSLTAVELRNR
MAV_3108|M.avium_104                PEQRQAELVELVCGNAAAVLG-HSTADVDPGDAFSDLGFDSLTAVELRNR
TH_4621|M.thermoresistible__bu      RPRRPPPPPDRVRHRAGPAHGPVRR-------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          LHSQFGGAFTINATAVFDYPTIGGLAEYLVAQLPDAETPQAAP-------
MAB_0939|M.abscessus_ATCC_1997      LHSQFGGKFTINATAVFDYPTIGGLAEYLVGQLPDADAESAEAPPAVESA
MSMEG_0408|M.smegmatis_MC2_155      LHSQFGGKFTINATAVFDYPTIGGLAEYLVGQLPDAEAPETA--------
Mvan_1003|M.vanbaalenii_PYR-1       LVGQFGSGFTITATAVFDYPTIGALAEYLAAQTPESTEEGTEMKTADPDG
Rv2947c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           LKTATG--LTLPPTVIFDHPTPTAVAEYVAQQMSGSRPTESGDPTSQVVE
MLBr_00135|M.leprae_Br4923          LKSATG--LTLPPTVIFDHPTPTAVAEYVAQQMLKSRPAESGDETSQAVE
MMAR_1762|M.marinum_M               LKSATG--LTLPPTVIFDHPTPTAIAEYVGRQIPDSQATQAEEE--KLPE
MUL_2005|M.ulcerans_Agy99           FKSATG--LTLPPTVIFDHPTPTAIAEYVGRQIPDSQATQAEEE--KLPE
MAV_3108|M.avium_104                LKIATG--LTLSPTVIFDHPTPAALAEHLGGQLTSAGPTPAAPAETAAPP
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          QSESEPGPDVTE--------------------------------------
MAB_0939|M.abscessus_ATCC_1997      EAESGAGPAAASDAVSELKE------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       QPATVGHADVVLQTS-----------------------------------
Rv2947c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           PAAAEVSVHA----------------------------------------
MLBr_00135|M.leprae_Br4923          PKVEEVSVHA----------------------------------------
MMAR_1762|M.marinum_M               SDGEMVSVTA----------------------------------------
MUL_2005|M.ulcerans_Agy99           SDGEMVSVTA----------------------------------------
MAV_3108|M.avium_104                DRSSRIDEVVSELQTLLTQPGLSPGDRAQLVTRLQSLLSTPPQPSGHPEF
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          ---------------------------
MAB_0939|M.abscessus_ATCC_1997      ---------------------------
MSMEG_0408|M.smegmatis_MC2_155      ---------------------------
Mvan_1003|M.vanbaalenii_PYR-1       ---------------------------
Rv2947c|M.tuberculosis_H37Rv        ---------------------------
Mb2971c|M.bovis_AF2122/97           ---------------------------
MLBr_00135|M.leprae_Br4923          ---------------------------
MMAR_1762|M.marinum_M               ---------------------------
MUL_2005|M.ulcerans_Agy99           ---------------------------
MAV_3108|M.avium_104                PEDAFDDDIATATDSQLFAILDDEAGP
TH_4621|M.thermoresistible__bu      ---------------------------