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M. gilvum PYR-GCK Mflv_0405 (-)

annotation: beta-ketoacyl synthase
coordinates: 407208 - 418247
length: 3679 

MGSAAHQGESAHRFAIVGYAGRFPGARDAESFWELLADGRDAISEVPEDRWDVEAFFDPDPSTPGKVVTR
RAGFVDDVSGFDAPFFGMSTREVRLMDPQHRLLLETAWRAIEHSGTAPSELANTNTGVFVGLATHDYLGM
ASDELSYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAIHQACQALRLGECDLALAGG
ANVILTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEGCGVIVIKRLEDAVRDGDRIRAVIRGSAINQ
DGASGGLTVPNGVAQQRVIGDALSRAGLAPGDVDYLEAHGTGTSLGDPIEAQAAGAALGPGREPQRPLLI
GSAKTNIGHLEAAAGIAGVIKVVLSLEHETLPKHLNFENPSPHIPWDRLPVEVVKESIPWRRGQRGGRPR
IAGVSSFGFAGTNAHVILEEAPLAAEPAQESVDDGRFTLLPLSARTPAALMAVADRYRDWLVANPDATLA
DLCFTAGTARSHLEHRAALVVNTREAALDLLGALADDRPAPGLVRGESHDTPKTAWLFTGQGSQYPGMSR
ELFDTEPLFAETLRECAAAVDGMLEKPLLDVIFDTDGVLDTDSNETLRHTSYAQPALFAVEMGLARLWQS
WGFEPDVVLGHSVGQYAAACVAGVLSLRDGARLMAERGRLFGSLPSGGRMAAVFAAAERVEALTDEYPAL
SVAAYNGANTVLSGPATDLERAVAGLVADGVRCDWLETSHAFHSALLDPILDDFESYARGITFTAPQRIL
IDNRTGAALGRSVTLDAAYWRRHARQPVEFAKSVHTLADMNCKLLVEIGPRPVLTAAALSAWPDPATSPR
VIASLRRTTADQRQITEAVADAYVLGHLPRFAAFRRDGARVLDLPTYPFEHRQYWFSDSREPVAAAPQRG
ARTETVRLLEDGRIEELAALLGGTVDDPFTFDVLNRLAAQHNQQRSTESIADDRYQIRWETAAEPPVGAD
AADGITWLLVGDDTDATRPLVDVLAARGHRYRILGLPKSGAEEHELADTLRDAAADATDLRIVHVAALDA
AESDTSMKSLLRMQHRVLGGTRRLFGAAVAAQLRSPMWLVTRGAQHVTDTDVVAPDQTCLWGFGRAASLE
HPQIWGGLADLGGGTSDEWSRLLNRIAATHDPAVMEDQVAVRGSTSYVPRLVHRDTLPSGKPLHLRADAT
YLVTGGLGSLGLEIAGYLAANGAGHLVLTSRRTPDEAAASRIEALRERHGCEVRVVTADVADAHAVARLL
ATVQAEMPPLAGIVHAAGEIGTTPLADLDDAEVDRVFAGKVWGAWHLSEATSDLQLDFFISTSSIASVWG
GFGQAAYGAANAFLDGLAWRLREQGVAGVSVNFGPWSAGMADAQSRARLEQRGIKTLSPADALAGLSDAV
ISAAPHPVVARVDWSRFLPLYQQAGRRGFLAELERELPAAPAQQGPAVTASGRTPLVERLTTAPLQQRKR
LLTDYLRDAVAEVTRVDAAEIREDAGFFDLGMDSLMAVELRRRIETGVGKEIPVTLVMDHPRLSDAADYL
LGDVLGLTEAATAPKAATVVSTAADEPIAIVAVSCRFPGAPNPEAFWDLLSGGVDAIREVPEDRFDIDEF
YDPDPDAAGKTYTRYGGFLDHIDEFDPEFFGLSPREAVWIEPQQRLMLETVWEGLERAGYAPSALRGSRT
GVFVGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGLEGPAVAVDTACSSSLVAVHQATQA
LRSGDCDMALAGGVNVLLSPVTVVAASRARMLSPVGRCKTFDASADGYVRSEGCGILVLKRLSDAVRDGD
RVCAVIAGSAVNQDGASSGLTVPNGGAQQRLIGTVLARAGITGGEVDYLEAHGTGTPLGDPIEVQAAAAA
YAGARDADRPLLMGSVKTNIGHTESASGAAGLIKVVLSLQHETLPQSLHFDTPSPHIPWDSLPVRVVDTA
MPWQPNGRPRRAGVSSFGFTGTNAHVLIEEAPTDLAGPTEPTAPAEPVDEDAAADPAPAPVEVLPLSARS
PEALVALAQRYETWLTAHPEADLADVCRTAGTGRSHFEHRAALVVDSVESARIALTDLAQNRLRPGVVRG
EHLNHPTTAWMFTGQGSQYPGMARELFDTEPVFADTVTRCADAVADLLPRPLLDVMFAGGREAGVPPTET
LRHTSFAQPALFAVEMGLARLWQSWGIVPDVVLGHSVGQYAAACVAGVFSLEDGARLMAERGRLFGSLPE
GGRMVAVFADAKRVEQVAADFPRVSVGAYNGPNTVLSGPGEDLEQIVGTFGEDGIRCTWLETSHAFHSEL
LDPVLDEFESYAAQLQFAAPTLPLVCNRTGAVLTGQTSLDAQYWRRHSRQPVQFAESVRTVAALGCSVLM
EIGPQPVLTGAAVQVWPEHLAAPRAIASLRKGVADRRQIADALAAAYIGGHKPDFAALHEQRGVRLELPT
YPFQRRRFWPKSAGMAIDGRVGASAGSGILGSGKDLASGDSVYTSRLSVKTQPWLSDHVIYGTVVVPGAT
YAAMALAAVGTPAHAKDVFFYEPIILPEKSSREVQLTVHPSVDGESKFQVHSRPYGERGAEWALNAEGVV
ASGVGDSPAAAGDLEDPVDEAIERLNRMRPQELFETFADLELAWGPTWSGSLKSLWLGEGEAIGDILVGA
ELAEQLGTEPMHPVLMDLCTGVAFPAFPALLAAEQGVNDLYLPLRYGQVSLQEKMPRRFYCRATWHEAPL
DSETQVFDLEYLDRDGRHLGGVREFTVKRAPREALLRGLGGDATRLLYTLGWHEVPVPESGDGAAPQGTW
LIGGFDELAVSVPGCIPADRTNPESLRQLLTDAHGRGLPFSGVVWRAARSDGDESDAEVAARLEAEIAEL
LGAVHTVQGGEVKLPGGLWIVTERAVATESGEPVDPVQAALWGFGRTAINEEPALRCRLVDCDGSPQAVQ
ALAALLSTPVDEPELAVRQGKLLASRLLPWSRSGHLTVPRGGDYVLAPTERGAIDNLRLTDSEVPPPAEG
YVQVRVEAAGLNFRDVLNVLGLYPGDPGPIGGDFAGTVTQLGEGVTGLDVGQRVYGSMQGAFASRFNVPG
QFLAPIPDGVSAVEAATIPAAALTVRLSFDWAQVKSGDKVLIHAASGGVGLAAVQMAQQCGAEVYATAST
FKRATLRKLGVKHVYDSRTTDFAEQILADTDGAGVDVVLNSLTSEGFIEATLRATAQHGRFAEIAKRDIW
TVEQMAAARPDLAYEIVALDTVMFTEPDRIRDLLTEVSAGLRDGAWTPLPAEVYPLTEARAAFRRMQQAR
HIGKIVVQIPNPLQPQPDRSYLITGGLGAIGLHTAGYLAQLGAGDIVLTSRRAPDAAAQQAIADIADRTK
ARLHVFTADVGVEADVAALLERIRAELPPLAGVAHLAGVLDDALLSQQSVERFRTALAPKAFGAVHLDRL
TRVDDLDFFLVSSSVSSLFGSPGQSNYATANAFLDGLVAQRRAQGLPATGVNFGPWARGGMASSEAAAAN
ISAQGLIPLEPSAALTAMAEVVANGTAQATVLKANWQRAAKVLGSSRPPILDLVLPSAVGEITGDSELLK
QLQEIPVPQRAGFVTEFLQKEVQNFLRLAQPPAATSRFLDLGTDSLMAIELRNRLHSQFGGAFTINATAV
FDYPTIGGLAEYLVAQLPDAETPQAAPQSESEPGPDVTE

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_0405--100% (3679)beta-ketoacyl synthase
M. gilvum PYR-GCKMflv_3393-0.034.05% (1592) beta-ketoacyl synthase
M. gilvum PYR-GCKMflv_3392-0.036.70% (1477) acyl transferase domain-containing protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2074cpks120.037.09% (2540) polyketide synthase pks12
M. tuberculosis H37RvRv2048cpks120.037.06% (2542) polyketide synthase pks12
M. leprae Br4923MLBr_00135-0.037.93% (2162) putative polyketide synthase
M. abscessus ATCC 19977MAB_0939-0.081.10% (3704) polyketide synthase
M. marinum MMMAR_3798-0.034.97% (3048) type I modular polyketide synthase
M. avium 104MAV_1763-0.077.50% (3685) tylactone synthase modules 4 & 5
M. smegmatis MC2 155MSMEG_0408-0.079.35% (3686) type I modular polyketide synthase
M. thermoresistible (build 8)TH_4621-0.034.47% (1938) PUTATIVE mycocerosic acid synthase
M. ulcerans Agy99MUL_2266pks120.036.68% (2549) polyketide synthase, Pks12
M. vanbaalenii PYR-1Mvan_0269-0.081.94% (3694) beta-ketoacyl synthase

CLUSTAL 2.0.9 multiple sequence alignment


Mb2074c|M.bovis_AF2122/97           MVDQLQHATEALRKALVQVERLKRTNRALLERSSEPIAIVGMSCRFPGGV
Rv2048c|M.tuberculosis_H37Rv        MVDQLQHATEALRKALVQVERLKRTNRALLERSSEPIAIVGMSCRFPGGV
MUL_2266|M.ulcerans_Agy99           MVDQLQHATEALRKALVQVERLKRTKRALLERSSEPIAIVGMSCRFPGGV
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               -MENEERLRKYLQKAANDLRKSNKRVRELERRTVEPVAVVGMACRFPGGA
Mflv_0405|M.gilvum_PYR-GCK          -----------------------MGSAAHQGESAHRFAIVGYAGRFPG-A
MAB_0939|M.abscessus_ATCC_1997      -----------------------MDSAENPIESTPRFAIIGYAARFPG-A
Mvan_0269|M.vanbaalenii_PYR-1       -----------------------MGSAEHPNGPAPRFAIVGYAARFPG-A
MSMEG_0408|M.smegmatis_MC2_155      -----------------------MVSAEHPIEPTPSFAIIGYAARFPG-A
MAV_1763|M.avium_104                -----------------------MSTVEGLRDPASSFAIVGYAARFPG-A
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           DSPEGLWQMVADARDVMSEFPTDRGWDLAGLFDPDPDVRHKSYARTGGFV
Rv2048c|M.tuberculosis_H37Rv        DSPEGLWQMVADARDVMSEFPTDRGWDLAGLFDPDPDVRHKSYARTGGFV
MUL_2266|M.ulcerans_Agy99           DSPEGLWQMVAEGRDVMSDFPTDRGWDLADLFDPDPDTPHKSYASTGGFV
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               DSPDGLWQMVSEGRDVLSEFPSDRGWDLGGLYDPEPDRVGYVHARAGGFL
Mflv_0405|M.gilvum_PYR-GCK          RDAESFWELLADGRDAISEVPEDR-WDVEAFFDPDPSTPGKVVTRRAGFV
MAB_0939|M.abscessus_ATCC_1997      ADAEEFWDVLREGRDAISEVPADR-WDAEEFFDPEPGAPGKVVTRRAGFV
Mvan_0269|M.vanbaalenii_PYR-1       PDADAFWDVLREGRDAISDVPRDR-WDAEEFFDPEPGAPGKVVTRRAGFV
MSMEG_0408|M.smegmatis_MC2_155      ASAEEYWALLRDGREAISDVPKDR-WDIEEFFDPDPSTPGKVVTRRAGFV
MAV_1763|M.avium_104                ADADEFWRVLAEGRDAVSEVPKDR-WDADEFFDPDPDAPGKVVTRRAGFV
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           DGVADFDPAFFGISPSEALAMDPQHRMLLELSWEALERAGIDPTGLRGSA
Rv2048c|M.tuberculosis_H37Rv        DGVADFDPAFFGISPSEALAMDPQHRMLLELSWEALERAGIDPTGLRGSA
MUL_2266|M.ulcerans_Agy99           DGVADFDPGFFGIAPSEALAMDPQHRMLLELSWEALERSGIDPTGLRGSA
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               DGVADFDAGFFGISPREALGMDPQQRLILEIAWETLESASIDPQSLRGSQ
Mflv_0405|M.gilvum_PYR-GCK          DDVSGFDAPFFGMSTREVRLMDPQHRLLLETAWRAIEHSGTAPSELANTN
MAB_0939|M.abscessus_ATCC_1997      EDVTGFDAPFFGMSTREVRLMDPQHRLLLETAWRAVEHSGIAPTDLAETN
Mvan_0269|M.vanbaalenii_PYR-1       DDVTGFDAPFFGMSTREVRMMDPQHRLLLETAWRAVEHSGTAPTALAGSN
MSMEG_0408|M.smegmatis_MC2_155      DDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSN
MAV_1763|M.avium_104                DDVTGFDAPFFGMSAREARLLDPQHRLLLETAWRAVEHSGTAPTDLANTN
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           TGVFAGLIVGGYG------MLAEEIEGYRLTGMTSSVASGRVAYVLGLEG
Rv2048c|M.tuberculosis_H37Rv        TGVFAGLIVGGYG------MLAEEIEGYRLTGMTSSVASGRVAYVLGLEG
MUL_2266|M.ulcerans_Agy99           TGVFAGLIVQGYG------MFAEEIEGYRLTGMTSSVASGRVAYVLGLEG
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               TGVFAGTMTSCYG------VGIDNVT---------SAVSGRVAYAFGFEG
Mflv_0405|M.gilvum_PYR-GCK          TGVFVGLATHDYLGMASDELSYPEIEAYMAIGTSNAAAAGRISYRLGLQG
MAB_0939|M.abscessus_ATCC_1997      SGVFVGLATHDYLGMASDELTFPEIEAYMAIGTSNAAAAGRISYRLGLQG
Mvan_0269|M.vanbaalenii_PYR-1       TGVFVGLATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQG
MSMEG_0408|M.smegmatis_MC2_155      TGVFVGLATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQG
MAV_1763|M.avium_104                TGVFIGISTHDYLGMASDELTYDQIEAYTAIGTSSAAAAGRISYRLGLQG
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           PAVSVDTACSSSLVALHMAVGSLRSGECDLALAGGVTVNATPTVFVEFSR
Rv2048c|M.tuberculosis_H37Rv        PAVSVDTACSSSLVALHMAVGSLRSGECDLALAGGVTVNATPTVFVEFSR
MUL_2266|M.ulcerans_Agy99           PAVSVDTACSSSLVALHMAVQSLRSGECDLALAGGATVNATPTVFVEFSR
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               PAVTVDTACSSSLVAIHQACQSLRGGECSMALAGGVTVMATPDVFAEFAR
Mflv_0405|M.gilvum_PYR-GCK          PAVAVDTACSSSLVAIHQACQALRLGECDLALAGGANVILTPATMITFSN
MAB_0939|M.abscessus_ATCC_1997      PSVAVDTACSSSLVAIHQACQALQLGECDLALAGGANVLLTPATMITFSH
Mvan_0269|M.vanbaalenii_PYR-1       PAVAVDTACSSSLVAIHQACQALRLGECDLALAGGANVLLTPATMITFSN
MSMEG_0408|M.smegmatis_MC2_155      PAVAVDTACSSSLVAIHQACQALRLNECDLALAGGANVLLTPATMITFSN
MAV_1763|M.avium_104                PAVAVDTACSSSLVAIHQACQALRLGECDLALAGGANVLLTPATMITFSQ
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           HRGLAPDGRCKPYAGRADGVGWSEGGGMLVLQRLSDARRLGHPVLAVVVG
Rv2048c|M.tuberculosis_H37Rv        HRGLAPDGRCKPYAGRADGVGWSEGGGMLVLQRLSDARRLGHPVLAVVVG
MUL_2266|M.ulcerans_Agy99           HRGLAPDGRSKAYAGAADGVGWSEGGAMLVVERLSDAQRLGHPVLALVRG
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               QRGLSADGRCKAFAASADGTGFGEGAGLVLLERLSDARRNRHPVLAVIRG
Mflv_0405|M.gilvum_PYR-GCK          AHMLAPDGRCKTFDAAADGYVRGEGCGVIVIKRLEDAVRDGDRIRAVIRG
MAB_0939|M.abscessus_ATCC_1997      AHMLAPDGKCKTFDAAADGYVRGEGSGVIVIKRLEDAIRDGDRIRAVIRG
Mvan_0269|M.vanbaalenii_PYR-1       AHMLAPDGRCKTFDAAADGYVRGEGCGVIVIKRLEDAVRDGDRIRAVIRG
MSMEG_0408|M.smegmatis_MC2_155      AHMLAPDGRCKTFDAAADGYVRGEGCGVVVVKRLEDAVRDGDRIRAVIRG
MAV_1763|M.avium_104                AHMLAPDGRCKTFDAAADGYVRGEGCGVLVVKRLEDAIRDGDRIRAVIRG
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           SAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTTL
Rv2048c|M.tuberculosis_H37Rv        SAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTTL
MUL_2266|M.ulcerans_Agy99           SAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTTL
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               SAVNQDGASNGLTAPNGPAQERVIRSAVAAAGLRVADVDVVEAHGTGTTL
Mflv_0405|M.gilvum_PYR-GCK          SAINQDGASGGLTVPNGVAQQRVIGDALSRAGLAPGDVDYLEAHGTGTSL
MAB_0939|M.abscessus_ATCC_1997      SAINQDGASGGLTVPNGVAQQRVIADALKRAGVAPSEVGYLEAHGTGTSL
Mvan_0269|M.vanbaalenii_PYR-1       SSINQDGASGGLTVPNGVAQQRVIADALKRSDLEPKDVGYLEAHGTGTSL
MSMEG_0408|M.smegmatis_MC2_155      SAINQDGASGGLTVPNGVAQQRVIADALKRAGLRPADVGYLEAHGTGTSL
MAV_1763|M.avium_104                SAINQDGASGGLTVPNGVAQQRVIAEALQRAGIAPGDVDYLEAHGTGTSL
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           GDPIEAQALLATYGQDRGEP---GEPLWLGSVKSNMGHTQAAAGVAGVIK
Rv2048c|M.tuberculosis_H37Rv        GDPIEAQALLATYGQDRGEP---GEPLWLGSVKSNMGHTQAAAGVAGVIK
MUL_2266|M.ulcerans_Agy99           GDPIEAQALLATYGQDRGSAGAAGKALWLGSIKSNMGHTQAAAGVAGVIK
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               GDPIEAHALLATYGADRDAE----QPLWLGSVKSNMGHTQAAAGVAGLIK
Mflv_0405|M.gilvum_PYR-GCK          GDPIEAQAAGAALGPGREPQ----RPLLIGSAKTNIGHLEAAAGIAGVIK
MAB_0939|M.abscessus_ATCC_1997      GDPIEAQAAGAAYGIGRETN----DPLLIGSAKTNIGHLEAAAGIAGVIK
Mvan_0269|M.vanbaalenii_PYR-1       GDPIEAQAAGAVLGAGREPS----RPLLIGSAKTNIGHLEAAAGIAGVIK
MSMEG_0408|M.smegmatis_MC2_155      GDPIEAQAAGEVLGAGRAPE----EPLLIGSAKTNIGHLEAAAGIAGVIK
MAV_1763|M.avium_104                GDPIEVQAAGAVLGAGREAS----RPLLIGSVKTNIGHLEAAAGIAGVIK
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           MVLAMRHELLPATLHVDVPSPHVDWSAGAVELLTAPRVWP---AGARTRR
Rv2048c|M.tuberculosis_H37Rv        MVLAMRHELLPATLHVDVPSPHVDWSAGAVELLTAPRVWP---AGARTRR
MUL_2266|M.ulcerans_Agy99           MVQAMRHEVLPATLHVDVPSPHVDWSAGAVELLTEAQPWPAESAGDRVRR
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               MIQAINHAVLPPTLHVDAPSPHIDWSAGAVRLLTEAVPWP---DTGRART
Mflv_0405|M.gilvum_PYR-GCK          VVLSLEHETLPKHLNFENPSPHIPWDRLPVEVVKESIPWRRGQRGGRPRI
MAB_0939|M.abscessus_ATCC_1997      VILSLENELLPQHRNFQNPSPHIPWDRLPVEVVREARPWGR---NGRPRI
Mvan_0269|M.vanbaalenii_PYR-1       VILSLEHRTLPKHLNFENPSPHIPWDRLAVEVVKETIPWER---DGGPRI
MSMEG_0408|M.smegmatis_MC2_155      VVMALENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQR---NGKPRI
MAV_1763|M.avium_104                VILALEHGMLPQHLHFRDPSPHIPWDRLAVQVVKEATAWQR---NGRPRV
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           AGVSSFGISGTNAHVIIEAVP---VVPRR-EAGW----AGPVVPWVVSAK
Rv2048c|M.tuberculosis_H37Rv        AGVSSFGISGTNAHVIIEAVP---VVPRR-EAGW----AGPVVPWVVSAK
MUL_2266|M.ulcerans_Agy99           AGVSSFGISGTNAHVIVEAAP---RVEVGGSSGG----AVPVVPWVVSAK
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               AGISSFGISGTNAHLIAQEAPQESTADPSPSDVC----EPLFRVWPVSGR
Mflv_0405|M.gilvum_PYR-GCK          AGVSSFGFAGTNAHVILEEAPLAAEPAQES------VDDGRFTLLPLSAR
MAB_0939|M.abscessus_ATCC_1997      AGVSSFGFAGTNAHVILEEAPVVSRDAVEPPA---PAGGRKFSILPLSAR
Mvan_0269|M.vanbaalenii_PYR-1       AGVSSFGFAGTNAHVILEEAPEQAAAPGPVQ-----QPDRRFSLLPLSAR
MSMEG_0408|M.smegmatis_MC2_155      AGVSSFGFAGTNAHVILEEAPAVGTPATTEP----VEDPRRYSVLPLSAR
MAV_1763|M.avium_104                AGVSSFGFAGTNAHVILEEAPDGTGRAAVPPAAVRPPGQRRFHVLPLSAR
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           SESALRGQAARLAAYVRGDDGLDVADVGWSLAG-RSVFEHRAVVVGG---
Rv2048c|M.tuberculosis_H37Rv        SESALRGQAARLAAYVRGDDGLDVADVGWSLAG-RSVFEHRAVVVGG---
MUL_2266|M.ulcerans_Agy99           SGSALGAQAARLAAHVRSHDELDVADVGWSLAG-RSTFEHRAVVLGA---
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               TAEALNAQAERLGQYLVDHPDLDLTDLAYSLATTRAHHAYRAAVTVPGDT
Mflv_0405|M.gilvum_PYR-GCK          TPAALMAVADRYRDWLVANPDATLADLCFTAGTARSHLEHRAALVVN---
MAB_0939|M.abscessus_ATCC_1997      TPAALAQLADKYRAWLNAHPEAALADLCFTAGVGRAHLEHRAALVVN---
Mvan_0269|M.vanbaalenii_PYR-1       TPAALTQLAGQYRDWWTAHPEATLADVCFTAGAGRAHLEHRAALVVN---
MSMEG_0408|M.smegmatis_MC2_155      TPEALVRLAGEYRDWLRAHPQARLADVSHTAGTARAHLEQRAALVVN---
MAV_1763|M.avium_104                TPAALVQIAGEYRDWLSAHPDTALADLCLTAGAGRAHFEHRAALVVD---
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           --DRDRLLAGLDELAGDQLG-GSVVRGTAT-AAGKTVFVFPGQGSQWLGM
Rv2048c|M.tuberculosis_H37Rv        --DRDRLLAGLDELAGDQLG-GSVVRGTAT-AAGKTVFVFPGQGSQWLGM
MUL_2266|M.ulcerans_Agy99           --DRDGLLAGLDELAGDEFGGASVIRGVAG-AAGKTVFVFPGQGSQWIGM
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               VNTRDDLLAGLRSLAVDQFHPGVTYHHYRLGQAGKTVFVFPGQGAQYAGM
Mflv_0405|M.gilvum_PYR-GCK          --TREAALDLLGALADDRPAPGLVRG--ESHDTPKTAWLFTGQGSQYPGM
MAB_0939|M.abscessus_ATCC_1997      --TREAAVELLSAVADDRPAPGLGRG--ESHDTPKTAWLFTGQGSQYPGM
Mvan_0269|M.vanbaalenii_PYR-1       --SAESAVELLGALADDRPAPGLVRG--ESHDTPKTAWLFTGQGSQYPGM
MSMEG_0408|M.smegmatis_MC2_155      --SRESAIELLGALADDRPAPGLVRG--ESHEAPKTAWLFTGQGSQYPGM
MAV_1763|M.avium_104                --STGSAGELLAALADDRPAPGLLRG--VCEDAPKTAWLFTGQGSQYAGM
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           GIELLDTAPAFAQQIDACAEAFAEFVDWSLVDVLRGAPGA------PGLD
Rv2048c|M.tuberculosis_H37Rv        GIELLDTAPAFAQQIDACAEAFAEFVDWSLVDVLRGAPGA------PGLD
MUL_2266|M.ulcerans_Agy99           GIELLDTAPVFARHIESCGQAFAEFVDWSLLDVLRGAAGA------PGLD
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               GAGLYRHHPVFTTAIDEICAVMDEHLDVPLRDVMFTEPG--------LLQ
Mflv_0405|M.gilvum_PYR-GCK          SRELFDTEPLFAETLRECAAAVDGMLEKPLLDVIFDTDGVLDTDSNETLR
MAB_0939|M.abscessus_ATCC_1997      ARELFETEPVFADTLNRCAAAVADVLEKPLLDVIFDVD---GPEAEETLR
Mvan_0269|M.vanbaalenii_PYR-1       ARELYDTEPVFAETLNRCAEAVADVLEKPLLDVIFDAE---ADDAEKTLQ
MSMEG_0408|M.smegmatis_MC2_155      ARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDAD-ELDGDTESPLR
MAV_1763|M.avium_104                ARELFDTEPVFAETLTRCATVLADVLEKPLLDVIFDTD---DPASEATLR
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           RVDVVQPVLFAVMVSLAELWKSVAVHPDAVIGHSQGEIAAAYVAGALSLR
Rv2048c|M.tuberculosis_H37Rv        RVDVVQPVLFAVMVSLAELWKSVAVHPDAVIGHSQGEIAAAYVAGALSLR
MUL_2266|M.ulcerans_Agy99           RIDVVQPVLFAVMVSLAELWKSVGVRPDAVIGHSQGEIAAAYVAGALSLR
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               QTVYAQPALFAFGVAMHAVLTQAGVNPDYLLGHSVGELTAAHVAGVLSLE
Mflv_0405|M.gilvum_PYR-GCK          HTSYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVGQYAAACVAGVLSLR
MAB_0939|M.abscessus_ATCC_1997      QTSYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVGQYSAACVAEVFSLE
Mvan_0269|M.vanbaalenii_PYR-1       NTCYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVGQYSAACVAGVFSLT
MSMEG_0408|M.smegmatis_MC2_155      HTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVE
MAV_1763|M.avium_104                QTSYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVGQYSAACVAGVLRVE
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           DAARVVTLRSKLLAGLAGPGGMVSIACGADQARDLLAPFGDRVSIAVVNG
Rv2048c|M.tuberculosis_H37Rv        DAARVVTLRSKLLAGLAGPGGMVSIACGADQARDLLAPFGDRVSIAVVNG
MUL_2266|M.ulcerans_Agy99           DAAKVVTLRSKLLVGLAGPGGMVSVACGEQQARELLEPFGDRVSIAAING
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               EAAVLVCARGRLMQSCT-PGAMMAISASEPAVAAMLENH-PEVVIAAVNG
Mflv_0405|M.gilvum_PYR-GCK          DGARLMAERGRLFGSLPSGGRMAAVFAAAERVEALTDEYPALSVAAYNG-
MAB_0939|M.abscessus_ATCC_1997      DGARLIAERGRLFSSLPAGGRMAAVFTDAERAERLTDEFPSLSVAAYNG-
Mvan_0269|M.vanbaalenii_PYR-1       DGARLMAERGRLFGSLPEGGRMVAVFTTAERAEAMTDEFPSLSVAAYNG-
MSMEG_0408|M.smegmatis_MC2_155      DGARLIAERGRLFGSLPAGGRMAAVFTAPERAERLTDEYPSLSVAAYNG-
MAV_1763|M.avium_104                DGARLIAERGRLFGSLPAGGRMVAAFAAAARVEGLTDEFPSLSVAAYNG-
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           PSAVVVSGEVGALEELIAVCSTKELRTRRIEVDYASHSVEVEAIRGPLAE
Rv2048c|M.tuberculosis_H37Rv        PSAVVVSGEVGALEELIAVCSTKELRTRRIEVDYASHSVEVEAIRGPLAE
MUL_2266|M.ulcerans_Agy99           PSAVVVSGEVAALEELIAQCADRELRTRRIDVDYASHSVEVEAIEGQLTE
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               PTSVAVAGPAEQLNALREHCNISNHKVTLLRVSHAFHSPAMDPILAEFEA
Mflv_0405|M.gilvum_PYR-GCK          -ANTVLSGPATDLERAVAGLVADGVRCDWLETSHAFHSALLDPILDDFES
MAB_0939|M.abscessus_ATCC_1997      -ANTVLSGPAQDLEKAIAALVADGVRCDFLETSHAFHSALLDPILDEFEA
Mvan_0269|M.vanbaalenii_PYR-1       -TNTVLSGPAGDLEKAVATLSADGVRCDWLDTSHAFHSALLDPILDDFES
MSMEG_0408|M.smegmatis_MC2_155      -ANTVLSGPAKDLESAVATLVADGVRCDWLDTSHAFHSALLDPILDDFES
MAV_1763|M.avium_104                -ANTVLSGPGQELEQAVARLTAEKVRCDWLDTSHAFHSALLDPILDEFES
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           ALSGIEPRSTRTVFFSTVTGNRLDTAGLD-ADYWYRNVRQTVLFDQAVRN
Rv2048c|M.tuberculosis_H37Rv        ALSGIEPRSTRTVFFSTVTGNRLDTAGLD-ADYWYRNVRQTVLFDQAVRN
MUL_2266|M.ulcerans_Agy99           VLAGIEPLSSRTAFFSSVTGSRLDTAELD-AEYWYRNIRQTVQFDQAVRS
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               IAKRLTYRPHSVPIMSNLTGSLATVEQLTSARYWAQHLRKPVRFYDGVTR
Mflv_0405|M.gilvum_PYR-GCK          YARGITFTAPQRILIDNRTGAALGRSVTLDAAYWRRHARQPVEFAKSVHT
MAB_0939|M.abscessus_ATCC_1997      YANQFNYKTPQRILIDNRTGTALGRSVKLDGAYWRRHARQPVEFAKSVRT
Mvan_0269|M.vanbaalenii_PYR-1       YANQFDFAAPQRILIDNRTGTALGRSVQLDGTYWRRHARQPVEFAKSVRT
MSMEG_0408|M.smegmatis_MC2_155      FAQKLEYREPQRILIDNRTGSALGRSTRLDGAYWRRHARQPVEFAKSVRT
MAV_1763|M.avium_104                YANQFDFGPPQRILICNRTGSALGRSVKLDGAYWRRHARQPVEFAKSVHT
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           ACEQGYRTFIESSPHPALITGVEETFAACTDGD-SEAIVVPTLGRGDGGL
Rv2048c|M.tuberculosis_H37Rv        ACEQGYRTFIESSPHPALITGVEETFAACTDGD-SEAIVVPTLGRGDGGL
MUL_2266|M.ulcerans_Agy99           ACGHGYRTFIESSPHPALIAGIEDTYRNCAADSGADPIVVPTLGREDGGL
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               LLAGGEQAFVELSPHPVLAAAITDTLTG--VTDRVGSAVVTTLRRDRPDM
Mflv_0405|M.gilvum_PYR-GCK          LADMNCKLLVEIGPRPVLTAAALSAWPDPATSP----RVIASLRRTTADQ
MAB_0939|M.abscessus_ATCC_1997      LADMNCKVLLEIGPQPVLTAAALRAWPDPATAP----RAIASLRRNTADH
Mvan_0269|M.vanbaalenii_PYR-1       LAEMNCKLLVEIGPRPVLTAAALGAWPDPATAP----RVIASLRRTAADH
MSMEG_0408|M.smegmatis_MC2_155      LADMNCRVLLEIGPRPVLTATALAAWPDPATTP----QVLASLRPTTADH
MAV_1763|M.avium_104                LADLGCKVLLEIGPQPVLTAAALRAWPDPATAP----RAIASLRRNTADH
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           HRFLLSAASAFVAGVAVNWRGTLD-GAGYVELPTYAFDKRRFWLSAEGSG
Rv2048c|M.tuberculosis_H37Rv        HRFLLSAASAFVAGVAVNWRGTLD-GAGYVELPTYAFDKRRFWLSAEGSG
MUL_2266|M.ulcerans_Agy99           QRFLASAAAAFVAGVNVDWRGPLD-GAGLVELPTYAFEKRRFWLSGEGVS
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               DMVASAIANLHVHGHSPSWQKIYP-GATTVELPTYPFQHRRYWLDP-APR
Mflv_0405|M.gilvum_PYR-GCK          RQITEAVADAYVLGHLPRFAAFRRDGARVLDLPTYPFEHRQYWFSDSRE-
MAB_0939|M.abscessus_ATCC_1997      RQITEAAADAYVLGHLPDFGAFQHAPARKLDLPTYPFERRQYWFSDKRDG
Mvan_0269|M.vanbaalenii_PYR-1       RQITEAVADAYVLGHLPEFGAFRDAGARKLDLPTYPFEHRQYWFRDNQDP
MSMEG_0408|M.smegmatis_MC2_155      RQITEAVAAAYAAGHLPDFRAFRQPDARKLDLPTYPFEHRQFWFSDNRAI
MAV_1763|M.avium_104                RQITEALAEAYIVGHLPDFGAAVG-PARKLDLPTYPFQHRQYWFSEQRVP
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           ADVSGLGLGASEHPLLGAVVDLPASGGVVLTGRLSPNVQPWLADHAVSDV
Rv2048c|M.tuberculosis_H37Rv        ADVSGLGLGASEHPLLGAVVDLPASGGVVLTGRLSPNVQPWLADHAVSDV
MUL_2266|M.ulcerans_Agy99           VDASGLGLSAGGHALLGAVVELPESGGVVLTGRLALGAHGWLADHAVSGV
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               ADVSAAGLDQPEHPLLAAVTELADQDQIVLSGRLSTSAHRWLAGHQLGDT
Mflv_0405|M.gilvum_PYR-GCK          --PVAAAPQR---GARTETVRLLEDGRIEELAALLGGTV-----------
MAB_0939|M.abscessus_ATCC_1997      DNRDAGNRQQNNGGPRTEAVRLLEDGKIEELANLLGGVD-----------
Mvan_0269|M.vanbaalenii_PYR-1       DGSEALQPRT----PSTEAVRLLEDGRIEELATLLDGAA-----------
MSMEG_0408|M.smegmatis_MC2_155      DRDTQTASAGSVTPHRTQAVRLLEDGQIEELAALIDGET-----------
MAV_1763|M.avium_104                PGSQQTSTQT-------TAVRLLEDGRIAELAELLDGAS-----------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           VLFPGTGFVELAIRAGDEVGCSVLDELTLAAPLLLPATGSVAVQVVVDAG
Rv2048c|M.tuberculosis_H37Rv        VLFPGTGFVELAIRAGDEVGCSVLDELTLAAPLLLPATGSVAVQVVVDAG
MUL_2266|M.ulcerans_Agy99           VVFPGTGFVELAIRAVDEVGCSVVNELTLRTPLVLPASGSVAVQVVVGAA
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               VVLPATALIDMALYAGEHTGCPTIDELVLQTPLTLTPDAATDLQISVAAP
Mflv_0405|M.gilvum_PYR-GCK          -----------------------------------DDPFTFDVLNRLAAQ
MAB_0939|M.abscessus_ATCC_1997      -----------------------------------GDQQTLNVLTKLAAQ
Mvan_0269|M.vanbaalenii_PYR-1       -----------------------------------GDQQTLDVLSRLAAQ
MSMEG_0408|M.smegmatis_MC2_155      -----------------------------------VDEQTLRVLNKLAAR
MAV_1763|M.avium_104                -----------------------------------ADQHTLDVLTKLAAQ
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           RDSNSRGVSIFSRADAQAG------WLLHAEGILRPGSVEPGADLSVWPP
Rv2048c|M.tuberculosis_H37Rv        RDSNSRGVSIFSRADAQAG------WLLHAEGILRPGSVEPGADLSVWPP
MUL_2266|M.ulcerans_Agy99           ADSAERSVSIYSRTDTDTDTDAGSVWVCHAEGTLGADSAQPAADLSAWPP
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               DEQNRRTFSVHARTSEHPHQHS--TWVLHASGTLSNAPSTTPPTKPLPGP
Mflv_0405|M.gilvum_PYR-GCK          HNQQRSTESIADDR-----------YQIRWETAAEPPVGADAADGITWLL
MAB_0939|M.abscessus_ATCC_1997      HNLQRTTQTIADDR-----------YQFRWEKSPTPLSGSQAAGGVTWLL
Mvan_0269|M.vanbaalenii_PYR-1       HNQQRSSQSITNDR-----------YEIRWEQSAAALSGAETDEVSSWIL
MSMEG_0408|M.smegmatis_MC2_155      HNQQRSTHVDPDAR-----------YEIRWDAIAS--AAASTGAAADWIL
MAV_1763|M.avium_104                HNQQRKSRSIAEDR-----------YEIRWEKSTVP----GPEAEATWLV
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           AGAVTVDVADGYERLATRGYRYGPAFRGLTAMWAR---GEEIFAEVRLPE
Rv2048c|M.tuberculosis_H37Rv        AGAVTVDVADGYERLATRGYRYGPAFRGLTAMWAR---GEEIFAEVRLPE
MUL_2266|M.ulcerans_Agy99           AGAIAVDVADGYERLDARGYGYGPAFRGLTAMWAR---GEELFAEARLPE
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               QAITKVNQESFYDQLAQHGLHYSEAFRSIQGIGKDPLNPDAICAEVALPA
Mflv_0405|M.gilvum_PYR-GCK          VGDDTDATRPLVDVLAARGHRYRILGLPKSGAEEH---------------
MAB_0939|M.abscessus_ATCC_1997      VADAAGAAQPLLDVLTARGQQHRVLALPVSDADEA---------------
Mvan_0269|M.vanbaalenii_PYR-1       VGDDTEATRPLVDVLSARGQRYRIFGLPVSDADEE---------------
MSMEG_0408|M.smegmatis_MC2_155      VGDDTAAVLEFADALTAGGHRHQIVALPGSDADEA---------------
MAV_1763|M.avium_104                VGDDDDAVAPLVDALTARGHQHRILVLPASDADEE---------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           AAGGVGGFGVHPALLDAVLHAVVIAGDPD----ELALPFAWQGVSLHATG
Rv2048c|M.tuberculosis_H37Rv        AAGGVGGFGVHPALLDAVLHAVVIAGDPD----ELALPFAWQGVSLHATG
MUL_2266|M.ulcerans_Agy99           AAGSTSGFGVHPALLDAALHTAVIANPDA----DLVLPFSWQGVSLHAAG
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               DIETHG-YGIHPALLDAALHPLTAALADTNTNSGPQLPFAIAGITLHATG
Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
Mvan_0269|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
MAV_1763|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           ASAVRARIAPAGPSAVSVELADGLGLPVLSVASMVARPVTERQLLAAVSG
Rv2048c|M.tuberculosis_H37Rv        ASAVRARIAPAGPSAVSVELADGLGLPVLSVASMVARPVTERQLLAAVSG
MUL_2266|M.ulcerans_Agy99           AASVRVRIAPVGPSSVSVELADDLGLPVLSVKAMVARPVSEQQMRAVVSA
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               ASRMHVQLEPTATDTFRLSATDPVGAPVITIDSLTVRSLPDTDLTQPPTH
Mflv_0405|M.gilvum_PYR-GCK          ----------ELADTLRDAAADATDLRIVHVAALDA--------------
MAB_0939|M.abscessus_ATCC_1997      ----------ELVEALRSAADEDSALRIVHVAALAG--------------
Mvan_0269|M.vanbaalenii_PYR-1       ----------QLGEALRLAAAEDSTLRIVHVGGLDSD-------------
MSMEG_0408|M.smegmatis_MC2_155      ----------QLVDTLRAASAG--ELYVVHIAAGDG--------------
MAV_1763|M.avium_104                ----------RLEIVLRAAAAEEAPLRIALVAALDS--------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           SGPDRLFEVIWSPA------------------------------------
Rv2048c|M.tuberculosis_H37Rv        SGPDRLFEVIWSPA------------------------------------
MUL_2266|M.ulcerans_Agy99           SGPDRLFEVVWTPM------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               KAQQGIFELTWPALPAETFPATGVLPPWALISPHPENLSPDLNQSPTYPN
Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
Mvan_0269|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
MAV_1763|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           -SAATSPGPTPAYQIFESVAADQDPVAGSYVRSHQALAAVQSWLT--DHE
Rv2048c|M.tuberculosis_H37Rv        -SAATSPGPTPAYQIFESVAADQDPVAGSYVRSHQALAAVQSWLT--DHE
MUL_2266|M.ulcerans_Agy99           -TVAAT-DAAPAYELFESIAADGDPLSGTYQRTHQALAAVQSWLT--EHD
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               LTALPTCPPLVIWDLTTPQPPQSDLLHQVHTLTQHTLAGLQNWLNRSDTL
Mflv_0405|M.gilvum_PYR-GCK          -------------------AESDTSMKSLLRMQHRVLGGTRRLFG-----
MAB_0939|M.abscessus_ATCC_1997      -------------------QGS-SSAQSLLRIQHQVLGGTRRLFR-----
Mvan_0269|M.vanbaalenii_PYR-1       -----------------PDPGTAPSMRSLLRMQHRILGGTRRLFR-----
MSMEG_0408|M.smegmatis_MC2_155      ---------------------AAAPMRDLLRVQHRTLGGLRRLFR-----
MAV_1763|M.avium_104                --------------------GTAPSMRSLLRMQHRVLAGTRRLFR-----
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           SGVLVVATRGAMALPREDVA-DLAGAAVWGLVRSAQTEHPGRIVLVDSDA
Rv2048c|M.tuberculosis_H37Rv        SGVLVVATRGAMALPREDVA-DLAGAAVWGLVRSAQTEHPGRIVLVDSDA
MUL_2266|M.ulcerans_Agy99           SGVLVVATRGAMALAGEDVT-DLAGAAVWGLVRSAQTENPGRLVLVDSDA
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               QAHLVVLTRHAVTTSPHDLAPDPAQAATAALIHTTQNEHPNRITLIDIDN
Mflv_0405|M.gilvum_PYR-GCK          ------------------------------AAVAAQLRSPMWLVTRGAQH
MAB_0939|M.abscessus_ATCC_1997      ------------------------------AAAAAELRAPIWIVTRGAQH
Mvan_0269|M.vanbaalenii_PYR-1       ------------------------------AAAAAELRTPIWVVTRRAQH
MSMEG_0408|M.smegmatis_MC2_155      ------------------------------AANDAELRSPIWLVTRDGQR
MAV_1763|M.avium_104                ------------------------------AAAAAELRQPIWLVTRGAQR
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           ATDDAAIAM---------ALATGEPQVVLRGGQVYTARVRGSRAADAILV
Rv2048c|M.tuberculosis_H37Rv        ATDDAAIAM---------ALATGEPQVVLRGGQVYTARVRGSRAADAILV
MUL_2266|M.ulcerans_Agy99           AVDAAAVAT---------ALAVGEPQVVLRNGQPYTARVHASRAADGILV
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               TPTTSQTLTNILTTLTNPTSAPTEPQLALRHGTPHTPRLTP----TQVLT
Mflv_0405|M.gilvum_PYR-GCK          VTDTDVVAP-----------------------------------------
MAB_0939|M.abscessus_ATCC_1997      VIEGDTVAP-----------------------------------------
Mvan_0269|M.vanbaalenii_PYR-1       VTATDTVAP-----------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      VTDTDTVVP-----------------------------------------
MAV_1763|M.avium_104                VTDADTVFP-----------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           PPGDGPWRLGLGSAGTFENLRLEPVPNADAPLGPGQVRVAMRAIAANFRD
Rv2048c|M.tuberculosis_H37Rv        PPGDGPWRLGLGSAGTFENLRLEPVPNADAPLGPGQVRVAMRAIAANFRD
MUL_2266|M.ulcerans_Agy99           PPVDGPWRLGLSSAGTFENLQLEPVPNAGAPLGPGQVRVAMRAIAANFRD
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               PPAAPNWELATTGKGDLANLALLPTP-PHTELGPGQIRVAVRAAGLNFRD
Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
Mvan_0269|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
MAV_1763|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           IMITLGMFTHDALLGGEGAGVVVEVGPGVTEFSVGDSVFGFFPDGSGTLV
Rv2048c|M.tuberculosis_H37Rv        IMITLGMFTHDALLGGEGAGVVVEVGPGVTEFSVGDSVFGFFPDGSGTLV
MUL_2266|M.ulcerans_Agy99           IMITLGMFTHDALIGGEGAGVVVEIGPEVTEFAVGDAVYGFFPDGSGTLV
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               VVVALGAIGEEG-LGGEAAGIIIDTGPDVTAFRRGDAVMGLFPNNAFAAT
Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
Mvan_0269|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
MAV_1763|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           AG-DVRLLLPMPADWSYAEAAAISAVFTTAYYAFIHLADVQPGQRVLIHA
Rv2048c|M.tuberculosis_H37Rv        AG-DVRLLLPMPADWSYAEAAAISAVFTTAYYAFIHLADVQPGQRVLIHA
MUL_2266|M.ulcerans_Agy99           AG-DVRLLLPKPADWSYAEAAAISAVFTTAYYAFVHLANVQPGQRVLVHA
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               AVTDHRMVVPIPAGWSFAAAASIPVAFLTAYGAMVELGALAAGRRVLIHA
Mflv_0405|M.gilvum_PYR-GCK          ---------DQTCLWGFGRAASLEHPQIWGGLADLGGGTSDEWSRLLNRI
MAB_0939|M.abscessus_ATCC_1997      ---------EQSALWGFGRAAALELPQVWGGLADLSDAGTDEWAQFIGRV
Mvan_0269|M.vanbaalenii_PYR-1       ---------DQSCLWGFGRAAALELPQLWGGLADLADGTADEWSRLLNRI
MSMEG_0408|M.smegmatis_MC2_155      ---------EQSCLWGFGRAAALELPHIWGGLADLSG-ADTEWPRLIARI
MAV_1763|M.avium_104                ---------DQSCLWGFGRAASLEYPQLWGGLADLAQGSAEEWSRLVRVA
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           GTGGVGMAAVQLARHLGLEVFATASKGKWDTLRAMGFDDDHISDSRSLEF
Rv2048c|M.tuberculosis_H37Rv        GTGGVGMAAVQLARHLGLEVFATASKGKWDTLRAMGFDDDHISDSRSLEF
MUL_2266|M.ulcerans_Agy99           ATGGVGMAAVQLARHLGLEVYATASKGKWDILRAMGFDEDHISDSRSLEF
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               GAGGVGQAAIQIARHFGAEVYATAHPSKHHVLKALGVSGDRIASSRTFDF
Mflv_0405|M.gilvum_PYR-GCK          AATHDPAVMEDQVAVRGSTSYVPRLVHRDTLPSGKPLHLR----------
MAB_0939|M.abscessus_ATCC_1997      SVSGEASTREDQLALRGQAVHVPRLVRREELPSGKPLEVR----------
Mvan_0269|M.vanbaalenii_PYR-1       TAPHGPAVREDQIALRDHAVYVPRLVRRAGRPAGKPLQLR----------
MSMEG_0408|M.smegmatis_MC2_155      TSPRD---GEDQIALRGDAVYAPRLVRRTGEPSDTPLPVR----------
MAV_1763|M.avium_104                SAPRDPAVGEDQIALRGSDIYVPRLTRRSGQPAAAALTLR----------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           EDKFRAATGGRGFDVVLDSLAGEFVDASLRLVAPGGVFLEMGKTDIRDPG
Rv2048c|M.tuberculosis_H37Rv        EDKFRAATGGRGFDVVLDSLAGEFVDASLRLVAPGGVFLEMGKTDIRDPG
MUL_2266|M.ulcerans_Agy99           EEKFREVTGGRSVDVVLDSLAGEFVDASLRLLGPGGVFLEMGKTDIRDPG
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               VDVFNQGTNGEGMDLVLNSLAGDFVDNSLRLLSQGGRLIEIGKTDIRVPN
Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
Mvan_0269|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
MAV_1763|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           VIAQQYPGVRYRAFDLFEAGPDRIAQILAELATLFGDGVLRPLPVTTFDV
Rv2048c|M.tuberculosis_H37Rv        VIAQQYPGVRYRAFDLFEPGRPRMHQYMLELATLFGDGVLRPLPVTTFDV
MUL_2266|M.ulcerans_Agy99           VIAQEYPGVRYRAFDLFEPGRPRMHQYMLDLAGLFDAGVLRPLPVTAFDV
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               EVAAAHPGVIYRTYDLSSETPDRISQLWAALIEMISAGVLRPLPTTSYGL
Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
Mvan_0269|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
MAV_1763|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           RRAPAALRYLSQARHTGKVVMLMPG----SWAAGTVLITGGTGMAGSAVA
Rv2048c|M.tuberculosis_H37Rv        RRAPAALRYLSQARHTGKVVMLMPG----SWAAGTVLITGGTGMAGSAVA
MUL_2266|M.ulcerans_Agy99           RRAPAALRYLSQARHVGKVVMTMPADQGGALGGGTVLITGGTGMAGSALA
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               LQATQALRHMSQGRHTGKIVLLPPG---VFNSEGTVLVTGGTGMLGGVFA
Mflv_0405|M.gilvum_PYR-GCK          -------------------------------ADATYLVTGGLGSLGLEIA
MAB_0939|M.abscessus_ATCC_1997      -------------------------------SDATYLVTGGLGSIGLEIA
Mvan_0269|M.vanbaalenii_PYR-1       -------------------------------DDATYLVTGGLGSIGLEIA
MSMEG_0408|M.smegmatis_MC2_155      -------------------------------EDRTYLVTGGLGAIGLEVA
MAV_1763|M.avium_104                -------------------------------ADATYLVTGGLGSIGLEIA
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           RHVVARHGVRNLVLVSRRGPDAPGAAELVAELAAAGAQVQVVACDAADRA
Rv2048c|M.tuberculosis_H37Rv        RHVVARHGVRNLVLVSRRGPDAPGAAELVAELAAAGAQVQVVACDAADRA
MUL_2266|M.ulcerans_Agy99           RHLVAHHGVAHLVLISRRGPAAPGATELVAELSAAGAQVEVVACDAADRP
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               ERLVAHYGARHLLLVSRSGPDAAGADELYQRLTQLGAQVTITACDTSNPD
Mflv_0405|M.gilvum_PYR-GCK          GYLAANG-AGHLVLTSRRTPDEAAASRIEALRERHGCEVRVVTADVADAH
MAB_0939|M.abscessus_ATCC_1997      GYLAGRG-AKHLVLTSRREPGEAARQRIDALAA-QGCEVRAVTADVADGH
Mvan_0269|M.vanbaalenii_PYR-1       GYLAAHG-ARHLVLTSRRAPGDATQQRIDALGAQHSCQIRVVAADVADAH
MSMEG_0408|M.smegmatis_MC2_155      GYLASHG-AGHVVLTSRREPGDDARRRLDGLREQYACDVRVITADVADAH
MAV_1763|M.avium_104                GHLAAQG-ARHLVLTGRRAPGEAAQRRIDALSQQHGCEVRVIAADVADAH
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           ALAKVIADIPVQHP-LSGVIHTAGALDDAVVMSLTPDRVDVVLRSKVDAA
Rv2048c|M.tuberculosis_H37Rv        ALAKVIADIPVQHP-LSGVIHTAGALDDAVVMSLTPDRVDVVLRSKVDAA
MUL_2266|M.ulcerans_Agy99           ALAKVIAENPAQRP-LSAVVHAGGVLDDAVISSLTPERVDTVLRAKVDAA
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               ELAAVLAGIPPQHP-LRAVVHTAGIVDDAVTTELTHEQLDTVLTAKADTA
Mflv_0405|M.gilvum_PYR-GCK          AVARLLATVQAEMPPLAGIVHAAGEIGTTPLADLDDAEVDRVFAGKVWGA
MAB_0939|M.abscessus_ATCC_1997      DVARLLAGIQAELPPLAGIVHAAGEIGTTPLSDLEDAEVDRVFAGKVWGA
Mvan_0269|M.vanbaalenii_PYR-1       DVARLLAAVAAELPPLAGIVHAAGEIGTTPLVSLEDSEVDRVFAGKVWGA
MSMEG_0408|M.smegmatis_MC2_155      DVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGA
MAV_1763|M.avium_104                HVARLLGAVRAELPPVAGIVHAAGEIGTTPLSDLEDAEIDRVFAGKVWGA
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           WHLHELTRDLD--VSAFVMFSSMAGLVGSSGQANYAAANSFLDALAAHRR
Rv2048c|M.tuberculosis_H37Rv        WHLHELTRDLD--VSAFVMFSSMAGLVGSSGQANYAAANSFLDALAAHRR
MUL_2266|M.ulcerans_Agy99           WNLHELTRDLD--LSAFVMFSSMAGVVGSSGQANYAAANTFVDGLAAHRR
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               WHLHQLTTDAD--LDAFVVFSSVAGVLGAPGQANYAAANAFLDALAHQRH
Mflv_0405|M.gilvum_PYR-GCK          WHLSEATSDLQ--LDFFISTSSIASVWGGFGQAAYGAANAFLDGLAWRLR
MAB_0939|M.abscessus_ATCC_1997      WHLSEAAAGLK--LDFFINTSSIAAVWGGYGQTAYSAANAFLDGLAWRLR
Mvan_0269|M.vanbaalenii_PYR-1       WHLSEAAADLQ--LDFFLGTSSIASVWGGYGQTAYGAANAFLDGLAWRLR
MSMEG_0408|M.smegmatis_MC2_155      WHLSEALTDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLR
MAV_1763|M.avium_104                WHLSEAAADLR--LDFFVSTSSIASVWGGLGQTAYGAANAFLDGLAWRLR
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           AHGLPAISLGWGLWDQASAMTSGLDAADLARLGREGVLALSTAEALELFD
Rv2048c|M.tuberculosis_H37Rv        AHGLPAISLGWGLWDQASAMTGGLDAADLARLGREGVLALSTAEALELFD
MUL_2266|M.ulcerans_Agy99           AHGLPAISLGWGLWDQASDMTGGMDAADRARLGREGVLALSSDEAMELFD
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               RNHLPATSLAWGYWQTTSGMTAHLDTVDQARLTRNSLTPITTEHGLAMFD
Mflv_0405|M.gilvum_PYR-GCK          EQGVAGVSVNFGPWSAG-----MADAQSRARLEQRGIKTLSPADALAGLS
MAB_0939|M.abscessus_ATCC_1997      EQGIAGTSVNFGPWSAG-----MADAESRARLEQRGIKTLSPTDALAGLA
Mvan_0269|M.vanbaalenii_PYR-1       EQGISGVSINFGPWSAG-----MADAESRARLDQRGVRTLSPADALAGLA
MSMEG_0408|M.smegmatis_MC2_155      ERGVTAVSVNFGPWAAG-----MADAESRARLEQRGVRTLSPAEALAGMA
MAV_1763|M.avium_104                EQGVNGISVNFGPWAAG-----MADENARARLAQRGIKTLSPADALAGLA
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           TAMIVDEPF------LAPARIDLTALRAHAVAVPPMFSDLASAPTRRQVD
Rv2048c|M.tuberculosis_H37Rv        TAMIVDEPF------LAPARIDLTALRAHAVAVPPMFSDLASAPTRRQVD
MUL_2266|M.ulcerans_Agy99           TALIVNQAF------LAPARIDLAALRAHAVAVPPMFSDLVSAPTRRQID
MLBr_00135|M.leprae_Br4923          ------------------------------------------------MT
MMAR_3798|M.marinum_M               VALACQHPC------LVPAPLNTQVLAGYARQN-----ALPAILSAVTTT
Mflv_0405|M.gilvum_PYR-GCK          DAVISAAP----HPVVARVDWSRFLPLYQQAGRRGFLAELERELPAAPAQ
MAB_0939|M.abscessus_ATCC_1997      DVVAASGSN-AVQGVIARIDWARFLPLYQQAGKRGFLAELDREVPSHLA-
Mvan_0269|M.vanbaalenii_PYR-1       DVVTAAEAPGPAQGIVARIDWERFLPLYQQAGRRAFLAELEREVPDTAP-
MSMEG_0408|M.smegmatis_MC2_155      DVVAGPVQG-----VVAKIDWSRFLPLYQQAGRRAFLSELESELPAAATG
MAV_1763|M.avium_104                DVMATAAAQ----GVVARIDWTRFLPLYQQAGQRSLLAELAREIPDFAP-
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           DSVAAAKSKSALAHRLHGLPEAEQHAVLLGLVRLHIATVLGNITPEAIDP
Rv2048c|M.tuberculosis_H37Rv        DSVAAAKSKSALAHRLHGLPEAEQHAVLLGLVRLHIATVLGNITPEAIDP
MUL_2266|M.ulcerans_Agy99           AALATAKSKSALAHRLHGLPELEQHAVVLDLVRSHIATVLGTITPEAIDP
MLBr_00135|M.leprae_Br4923          ASVEGADQK-----------------------------------------
MMAR_3798|M.marinum_M               RRQATTTNTETFTSRLASQTPQQQLAILSDLVTDMTAAVLAHPDSAALDA
Mflv_0405|M.gilvum_PYR-GCK          QGPAVTASGRTPLVERLTTAPLQQRKRLLTDYLRDAVAEVTRVDAAEIRE
MAB_0939|M.abscessus_ATCC_1997      -GVAGAQSGSTQLVERLANAPVQQRKKLLTDYLRDAVAEVTRVDVSEIRE
Mvan_0269|M.vanbaalenii_PYR-1       ---AATPSGRTELVERLTNAPVQQRKKLLTDYLRTAVAEITRVDATEIRE
MSMEG_0408|M.smegmatis_MC2_155      AAAPATVPGKPPLVEQLTKAPVQQRKSLITNYLRNAVAEVTRVDADEIRD
MAV_1763|M.avium_104                ---APTPSGKTGLVERLAGAPVQQRRKLMTEFLRNAVAEVTRVDAAEIRE
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           DKAFQDLGFDSLTAVEMRNRLKSATGLSLSPTLIFDYPTPNRLASYIRTE
Rv2048c|M.tuberculosis_H37Rv        DKAFQDLGFDSLTAVEMRNRLKSATGLSLSPTLIFDYPTPNRLASYIRTE
MUL_2266|M.ulcerans_Agy99           DKAFQELGFDSLTAVEMRNRIKTVTGLSLSPTLIFDYPTPNGLANYIRAE
MLBr_00135|M.leprae_Br4923          ---------------------------------------SEKLISYLKKV
MMAR_3798|M.marinum_M               DLPFKDLGIDSLSALELRNSLARHTGLTLSATLVFDHPTPTAIAHHLVDQ
Mflv_0405|M.gilvum_PYR-GCK          DAGFFDLGMDSLMAVELRRRIETGVGKEIPVTLVMDHPRLSDAADYLLGD
MAB_0939|M.abscessus_ATCC_1997      DAGFFDLGMDSLMAVELRRRMEQGVGKEIPVTLVMDHPRISDVADYLLGD
Mvan_0269|M.vanbaalenii_PYR-1       DAGFFDLGMDSLMAVELRRRIEQGVGREIPATLAMDHPRLSDVADYLLGE
MSMEG_0408|M.smegmatis_MC2_155      EAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVE
MAV_1763|M.avium_104                DAGFFDLGMDSLMAIELRRHIEQGVGKQIPATLAMDYPRLSDVAEYLLGD
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           LAGLPQEIKHTPAVRTTS-------EDPIAIVGMACRYPGGVNSPDDMWD
Rv2048c|M.tuberculosis_H37Rv        LAGLPQEIKHTPAVRTTS-------EDPIAIVGMACRYPGGVNSPDDMWD
MUL_2266|M.ulcerans_Agy99           LAGAPQEVKHTPAVRVTG-------DDPIAIVGMSCRYPGGIESPDDLWD
MLBr_00135|M.leprae_Br4923          VVELDETRARLREYEQRA-------TEPVAVVGIGCRFPGGVDSPDRLWD
MMAR_3798|M.marinum_M               LSAAAPPAPVATPVKANA-------EEPVVVVGMACRLPGGIESAAGLWD
Mflv_0405|M.gilvum_PYR-GCK          VLGLTEAAT---APKAAT-VVSTAADEPIAIVAVSCRFPG-APNPEAFWD
MAB_0939|M.abscessus_ATCC_1997      VLGLAEQAKP--AAQLAS-AVTGRTDEPIAIVAVSCRFPG-APDPEAFWD
Mvan_0269|M.vanbaalenii_PYR-1       VLGLAEQAPAKAGSQPAS-AAANRTDEPIAIVAVSCRFPG-APDPEAFWE
MSMEG_0408|M.smegmatis_MC2_155      VLGLGEQTN----VRQAS-TVTARTDDPIAVVAVSCRFPG-APDPESFWE
MAV_1763|M.avium_104                VLDLRGQPDAKPAPPAGTPAPAGRTDEPIAIVAMACRFPG-AADPEAFWE
TH_4621|M.thermoresistible__bu      ----------VNIVGDTP-------VNAVAVIGMACRLPGGIDSPQRLWE
                                                              :.:.::.:.** **   ..  :*:

Mb2074c|M.bovis_AF2122/97           MLIQGRDVLSEFPADRGWDLAGLYNPDPDAAGACYTRTGGFVDGVGDFDP
Rv2048c|M.tuberculosis_H37Rv        MLIQGRDVLSEFPADRGWDLAGLYNPDPDAAGACYTRTGGFVDGVGDFDP
MUL_2266|M.ulcerans_Agy99           MLMARRDVLSDFPADRGWDLAGLFNPDPDVPGACYTRTGGFVDRVGDFEP
MLBr_00135|M.leprae_Br4923          VVSECRDVVSEFPTDRGWDVDGLFDPDPDAEGKTYTRWGAFLDDAAGFDA
MMAR_3798|M.marinum_M               VVSGAADVMGAFPTDRGWDVAGLFDPDPDSVGKTYTRYGGFISSAAEFDA
Mflv_0405|M.gilvum_PYR-GCK          LLSGGVDAIREVPEDR-FDIDEFYDPDPDAAGKTYTRYGGFLDHIDEFDP
MAB_0939|M.abscessus_ATCC_1997      VLSGGVDAIREVPEDR-FDIDEFYDPDPEVAGKTYTRFGGFLDGIDGFDP
Mvan_0269|M.vanbaalenii_PYR-1       VLAGGVDAIREVPEDR-FDIDEFYDPDPDAAGKTYTRFGGFLDGIDGFDP
MSMEG_0408|M.smegmatis_MC2_155      LLAGGVDAIREVPEDR-WDIDEFYDPDPDTPGKTYTRFGGFLDGIDGFDP
MAV_1763|M.avium_104                LLSGGVDAIREVPEDR-FDIDEFYDPDPETPGKMYSRFGGYLDQIDEFDP
TH_4621|M.thermoresistible__bu      ALLRGDDMVTEIPVDR-WDADDYFDPEPGVPGRTVSRWGAFLDDVAGFDP
                                     :    * :  .* ** :*    ::*:*   *   :* *.::.    *:.

Mb2074c|M.bovis_AF2122/97           AFFGVGPSEALAMDPQQRMLLELSWEALERAGIDPTGLRGSATGVFAGVM
Rv2048c|M.tuberculosis_H37Rv        AFFGVGPSEALAMDPQHRMLLELSWEALERAGIDPTGLRGSATGVFAGVM
MUL_2266|M.ulcerans_Agy99           AFFGVGPSEALAMDPQQRMFLELSWEALERAGIEPGGLRGSATGVFAGVM
MLBr_00135|M.leprae_Br4923          GFFGIAPSEVLAMDPQQRLMLEVSWEALEYAGIDPLSLRGSATGVFTGIF
MMAR_3798|M.marinum_M               EFFGISAREAAAMDPQQRVLLEVCWEALEHAGIEPGTLEGSNTGVFIGAY
Mflv_0405|M.gilvum_PYR-GCK          EFFGLSPREAVWIEPQQRLMLETVWEGLERAGYAPSALRGSRTGVFVGVA
MAB_0939|M.abscessus_ATCC_1997      EFFGISPREAVWIEPQQRLMLETVWEGLERAGYSPAALRGSRTGIFAGVG
Mvan_0269|M.vanbaalenii_PYR-1       EFFGISPREAVWIEPQQRLMLETVWEGLERAGLAPADLRGSRTGIFVGVA
MSMEG_0408|M.smegmatis_MC2_155      EFFGISPREAVWIEPQQRLMLETVWEGLERAGYAPSDLRGSRTGVFTGVA
MAV_1763|M.avium_104                EFFGISPREAVWIDPQQRLVLETVWEGLERAGYSPAALRGSRSGIFVGVG
TH_4621|M.thermoresistible__bu      EFFGISEREAISIDPQQRLLLETSWEAMEHAGLTPADVEGSSTGVFVGLS
                                     ***:.  *.  ::**:*:.**  **.:* **  *  :.** :*:* *  

Mb2074c|M.bovis_AF2122/97           TQGYGMFAA----EPVEGFRLTGQLSSVASGRVAYVLGLEGPAVSVDTAC
Rv2048c|M.tuberculosis_H37Rv        TQGYGMFAA----EPVEGFRLTGQLSSVASGRVAYVLGLEGPAVSVDTAC
MUL_2266|M.ulcerans_Agy99           TQGYGMFAA----EPVEGFRLTGQLSSVASGRVAYVLGLEGPAVSVDTAC
MLBr_00135|M.leprae_Br4923          APSYGSRDT----GGLQGYGLTGTAVSVASGRVSYVLGLEGPAVSVDTAC
MMAR_3798|M.marinum_M               AQRYGDSDS----DSGEGFALTGGATSVASGRVAYVLGLQGPAITVDTAC
Mflv_0405|M.gilvum_PYR-GCK          ANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGLEGPAVAVDTAC
MAB_0939|M.abscessus_ATCC_1997      ANEYAHLLSSESIDKIEPYFITGNALNAISGRVAFALGFEGPAVAVDTAC
Mvan_0269|M.vanbaalenii_PYR-1       ANEYAHLLSSESIEKIEPHFITGNALNAISGRVAFALGLEGPAVAVDTAC
MSMEG_0408|M.smegmatis_MC2_155      ANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGFEGPAVAVDTAC
MAV_1763|M.avium_104                ANEYSHLLSAESVDKIEPHFITGNALNAISGRVAFALGLEGPAVAVDTAC
TH_4621|M.thermoresistible__bu      HDDYALLTSDAG-ALEEAYGFTGSAFSMASGRIAYRLGVHGPAVTVDTAC
                                       *.   :       : . :**   .  ***::: **..***::*****

Mb2074c|M.bovis_AF2122/97           SSSLVALHMAVGSLRSGECDLALAGGVTVNATPDIFVEFSRWRGLSPDGR
Rv2048c|M.tuberculosis_H37Rv        SSSLVALHMAVGSLRSGECDLALAGGVTVNATPDIFVEFSRWRGLSPDGR
MUL_2266|M.ulcerans_Agy99           SSSLVALHMAVQSLRSGECDLALAGGVTINATPDIFVEFSRWRGLSADGR
MLBr_00135|M.leprae_Br4923          SSSLVAIHWAMSSLRSGECDLALAGGVTVMGLPSIFVGFSRQRGLAADGR
MMAR_3798|M.marinum_M               SSSLVAAHLACQSLRNGESSLALAGGVTIMATPAPFIEFARQRGLAADGR
Mflv_0405|M.gilvum_PYR-GCK          SSSLVAVHQATQALRSGDCDMALAGGVNVLLSPVTVVAASRARMLSPVGR
MAB_0939|M.abscessus_ATCC_1997      SSALVAVHQAVQALHSGDCDLALAGGVNVLLSPVTVIAASRARMLSPVGR
Mvan_0269|M.vanbaalenii_PYR-1       SSALVAVHQACQALHSGDCDLALAGGVNVLLSPVTSVAASRARMLSPVGR
MSMEG_0408|M.smegmatis_MC2_155      SSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGR
MAV_1763|M.avium_104                SSSLVAVHQACQALHSGDCDLALAGGVNVLLSPVSNIAASRARMLSPVGR
TH_4621|M.thermoresistible__bu      SSSLLAVHMACRSLQVGESDLALAGGAMVMLEPRKYTSASGLGMLSPTGR
                                    **:*:* * *  :*: *:..:*****. :   *      :    *:. **

Mb2074c|M.bovis_AF2122/97           CKAFAAAADGTGFSEGGGMLVLQRLSDARRLGHPVLAVVVGSAVNQDGAS
Rv2048c|M.tuberculosis_H37Rv        CKAFAAAADGTGFSEGGGMLVLQRLSDARRLGHPVLAVVVGSAVNQDGAS
MUL_2266|M.ulcerans_Agy99           CKAFAGAADGTGFSEGGGMLVVERLSDAQRLGHPVLALVRGSAVNQDGAS
MLBr_00135|M.leprae_Br4923          CKAFARAADGTGWGEGAGVVVLERLSDAQRLGHTVLAVVRGSAVNQDGAS
MMAR_3798|M.marinum_M               CKAFAAAADGTGWGEGAAVLVLERLSDARRNRHPVLAVIAGSAVNQDGAS
Mflv_0405|M.gilvum_PYR-GCK          CKTFDASADGYVRSEGCGILVLKRLSDAVRDGDRVCAVIAGSAVNQDGAS
MAB_0939|M.abscessus_ATCC_1997      CKTFDASADGYVRSEGCGILVLKRLSDAERDGDRVLAVIPGSAVNQDGAS
Mvan_0269|M.vanbaalenii_PYR-1       CKTFDASADGYVRSEGCGILVLKRLGDAVRDGDRVCAVIPSSAVNQDGAS
MSMEG_0408|M.smegmatis_MC2_155      CKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGAS
MAV_1763|M.avium_104                CKTFDATADGYVRSEGCGILVLKRMSDAVRDGDRVCAVIPASAVNQDGAS
TH_4621|M.thermoresistible__bu      CHAFDVAADGFVRSEGSVMLLLKRLPDALRDNDRILAVVRGTAANQDGRT
                                    *::*  :***   .**  :::::*: ** *  . : *:: .::.**** :

Mb2074c|M.bovis_AF2122/97           NGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTTLGDPIEAQAL
Rv2048c|M.tuberculosis_H37Rv        NGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTTLGDPIEAQAL
MUL_2266|M.ulcerans_Agy99           NGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTTLGDPIEAQAL
MLBr_00135|M.leprae_Br4923          NGLTAPNGLAQQRVIQAALTNAGLSSADVDVVEAHGTATTLGDPIEAQAL
MMAR_3798|M.marinum_M               NGLSAPNGPAQQRVIAQAAANAGIALDQVDVVEAHGTGTTLGDPIEAGAL
Mflv_0405|M.gilvum_PYR-GCK          SGLTVPNGGAQQRLIGTVLARAGITGGEVDYLEAHGTGTPLGDPIEVQAA
MAB_0939|M.abscessus_ATCC_1997      SGLTVPNGGAQQRLIGSVLARAGLVGGDVDYLEAHGTGTPLGDPIEVQAA
Mvan_0269|M.vanbaalenii_PYR-1       SGLTVPNGGAQQRLIGMALARAGLSGGDVDYLEAHGTGTPLGDPIEVQAA
MSMEG_0408|M.smegmatis_MC2_155      SGLTVPNGGAQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQAA
MAV_1763|M.avium_104                SGLTVPNGGAQQRLIATALSRAGLSGDDVDYLEAHGTGTALGDPIEVQAA
TH_4621|M.thermoresistible__bu      ENISTPSIQAQADVYRSALAVAGVDPATVGMVEAHGTGTPVGDPIEYNSL
                                    ..::.*.  :*  :   . : **:    *. :*.***.*.:*****  : 

Mb2074c|M.bovis_AF2122/97           LATYGQDRGEP---GEPLWLGSVKSNMGHTQAAAGVAGVIKMVLAMRHEL
Rv2048c|M.tuberculosis_H37Rv        LATYGQDRGEP---GEPLWLGSVKSNMGHTQAAAGVAGVIKMVLAMRHEL
MUL_2266|M.ulcerans_Agy99           LATYGQDRGSAGAAGKALWLGSIKSNMGHTQAAAGVAGVIKMVQAMRHEV
MLBr_00135|M.leprae_Br4923          LATYGQGRPAD----QPLWVGSIKSNMGHTQAAAGVAGVIKMVQAMRHHV
MMAR_3798|M.marinum_M               IATYGTHRDPE----HPLWLGSVKSNIGHTQAAAGAAGLIKMIQAMRHGV
Mflv_0405|M.gilvum_PYR-GCK          AAAYAGARDAD----RPLLMGSVKTNIGHTESASGAAGLIKVVLSLQHET
MAB_0939|M.abscessus_ATCC_1997      AAAYGGSRDAD----RPLLMGSVKSNIGHTESASGAAGLIKVVLSLQNGV
Mvan_0269|M.vanbaalenii_PYR-1       AAAYGASRDAD----RPLLMGSVKTNIGHLESASGAAGLIKVVLSLQHNL
MSMEG_0408|M.smegmatis_MC2_155      AAAYGAGRDAD----RPLLMGSVKTNIGHTESASGAAGLIKVVLSLQHGV
MAV_1763|M.avium_104                GAVYGATRDTD----RPLLIGSVKTNIGHLEAASGVAGLIKVVLSLQHEM
TH_4621|M.thermoresistible__bu      TQVYGKTGPCA--------LTSVKTNFGHAESAAGALGMMKAILALQHGV
                                      .*.              : *:*:*:** ::*:*. *::* : ::::  

Mb2074c|M.bovis_AF2122/97           LPATLHVDVPSPHVDWSAGAVELLTAPRVWP---AGARTRRAGVSSFGIS
Rv2048c|M.tuberculosis_H37Rv        LPATLHVDVPSPHVDWSAGAVELLTAPRVWP---AGARTRRAGVSSFGIS
MUL_2266|M.ulcerans_Agy99           LPATLHVDVPSPHVDWSAGAVELLTEAQPWPAESAGDRVRRAGVSSFGIS
MLBr_00135|M.leprae_Br4923          MPATLHVDEPSPRVDWTTGAVSVLTEARDWS---VEGRPRRAGVSSFGIS
MMAR_3798|M.marinum_M               LPKTLHVNAPTPQVDWSAGTVRLLTETMPWP---DTDHLRTAAVSSFGVS
Mflv_0405|M.gilvum_PYR-GCK          LPQSLHFDTPSPHIPWDSLPVRVVDTAMPWQ---PNGRPRRAGVSSFGFT
MAB_0939|M.abscessus_ATCC_1997      LPQSLHFDNPSPHIPWESLPVRVVDKAIPWQ---ANGRPRRAGVSSFGFT
Mvan_0269|M.vanbaalenii_PYR-1       LPQSLHFENPSPHIPWDSLPVRVVDKAIPWQ---ADGRPRRAGVSSFGFT
MSMEG_0408|M.smegmatis_MC2_155      LPQSLHFENPSPHIPWDALPVRVIDEPVPWQ---TNGRVRRAGVSSFGFT
MAV_1763|M.avium_104                LPQSLHFETPSPHIPWDSLPLRVVDKAVPWQ---TNGRPRRAGVSSFGFT
TH_4621|M.thermoresistible__bu      VPQNLHFTRLPDEMAAIETNLFVPQATTLWP--VREGCPRRAAVSSYGMS
                                    :* .**.   . .:      : :   .  *         * *.***:*.:

Mb2074c|M.bovis_AF2122/97           GTNAHVIIEA-VPVVPRR------------EAGWAGP---VVPWVVSAKS
Rv2048c|M.tuberculosis_H37Rv        GTNAHVIIEA-VPVVPRR------------EAGWAGP---VVPWVVSAKS
MUL_2266|M.ulcerans_Agy99           GTNAHVIVEA-APRVEVGG-----------SSGGAVP---VVPWVVSAKS
MLBr_00135|M.leprae_Br4923          GTNAHVILEE-APTPVEAS-----------YSTADQQRLSVVPWVVSGRS
MMAR_3798|M.marinum_M               GTNAHLIVQQGSPGPAVAV-----------HQASPSQECSLGVWPLSARS
Mflv_0405|M.gilvum_PYR-GCK          GTNAHVLIEEAPTDLAGPTEPTAPAEPVDEDAAADPAPAPVEVLPLSARS
MAB_0939|M.abscessus_ATCC_1997      GTNAHVLIEEAPQPQATP----------DEDDASTPQSAPVSVLPLSARS
Mvan_0269|M.vanbaalenii_PYR-1       GTNAHVLIEEAPLPQAAD-----------PVEEPDTRALPVGVLALSARS
MSMEG_0408|M.smegmatis_MC2_155      GTNAHVLVEEAPPQLHTADAAP----VEPAATAEAGTDDSPQVLALSARS
MAV_1763|M.avium_104                GTNAHVLIEEAPQPVTTQ----------DATPAAESDARPVDVLPLSARS
TH_4621|M.thermoresistible__bu      GTNVHAVLEQAPEPVQRPE------------ESADTDAAGPLVFALSSTS
                                    ***.* :::                                    :*. *

Mb2074c|M.bovis_AF2122/97           ESALRGQAARLAAYVRGD-DGLDVADVGWSLAG-RSVFEHRAVVVGG---
Rv2048c|M.tuberculosis_H37Rv        ESALRGQAARLAAYVRGD-DGLDVADVGWSLAG-RSVFEHRAVVVGG---
MUL_2266|M.ulcerans_Agy99           GSALGAQAARLAAHVRSH-DELDVADVGWSLAG-RSTFEHRAVVLGA---
MLBr_00135|M.leprae_Br4923          TAALMAQASRLAFYVQAD-PEVDPVDVGCALAA-RSVFEHRAVVVGE---
MMAR_3798|M.marinum_M               SAGLSAQAHRLHEYLLGH-SDLDLIDLAYSLATTRTHHSYRAAVTVPGCT
Mflv_0405|M.gilvum_PYR-GCK          PEALVALAQRYETWLTAH-PEADLADVCRTAGTGRSHFEHRAALVVD---
MAB_0939|M.abscessus_ATCC_1997      PEALAAVAQRYESWLAAH-PDVDLEDVCLTAGRGRSHFEHRAALVVD---
Mvan_0269|M.vanbaalenii_PYR-1       PEALTALAQRYEAWLSAH-PDADLADVCRTAGTGRSHFEHRAALVVD---
MSMEG_0408|M.smegmatis_MC2_155      PEALVELARRYDDWLSAT-PGLDIADVCHTAGVGRSHFEYRAALVVD---
MAV_1763|M.avium_104                PEALLALAQRYGEWLHAH-PDADIGDLCFTVGAGRAHFEHRAALVVD---
TH_4621|M.thermoresistible__bu      AEELRRTAGRLAEWVEAHTDEVVPADLAYTLARRRAHRPVRTTVIADG--
                                       *   * *    : .        *:  : .  *:    *:.:      

Mb2074c|M.bovis_AF2122/97           --DRDRLLAGLDELAGDQLG--GSVVRGTATAAGKTVFVFPGQGSQWLGM
Rv2048c|M.tuberculosis_H37Rv        --DRDRLLAGLDELAGDQLG--GSVVRGTATAAGKTVFVFPGQGSQWLGM
MUL_2266|M.ulcerans_Agy99           --DRDGLLAGLDELAGDEFGG-ASVIRGVAGAAGKTVFVFPGQGSQLLGM
MLBr_00135|M.leprae_Br4923          --SREQLIAGLAGLAVGESG--AGVAIGQAAPLGKTVVVFPGQGAQRIGM
MMAR_3798|M.marinum_M               DNAHHDLLGGLTALAAGQTHPFVANHYCRAGQNGKTVFVFPGQGGQYPAM
Mflv_0405|M.gilvum_PYR-GCK          --SVESARIALTDLAQNRLR--PGVVRGEHLNHPTTAWMFTGQGSQYPGM
MAB_0939|M.abscessus_ATCC_1997      --SIQTAREGLLELAQNRLR--PGVVRGEHTNHPTTAWLFTGQGSQYPGM
Mvan_0269|M.vanbaalenii_PYR-1       --SVAAAREGLAELAQNRLR--PGVVRGEHTHHPTTAWLFTGQGSQFPGM
MSMEG_0408|M.smegmatis_MC2_155      --SVERAREGLAALAEGRTP--AGVVRGEHVHRPTTAWLFTGQGSQYPGM
MAV_1763|M.avium_104                --SVRSAREALADLADNRTR--PGVARGECTDPPTTAWLFTGQGSQYPGM
TH_4621|M.thermoresistible__bu      ---VEALTAGLREVADGDAP----YQPAVGMDDKAPVWVFSGQGSQWAGM
                                             .*  :* .                  .. :*.***.*  .*

Mb2074c|M.bovis_AF2122/97           GMGLHAGYPVFAEAFNTVVGELDRHLLRPLREVMWG-------HDENLLN
Rv2048c|M.tuberculosis_H37Rv        GMGLHAGYPVFAEAFNTVVGELDRHLLRPLREVMWG-------HDENLLN
MUL_2266|M.ulcerans_Agy99           GMGLHAGYPVFAEAFNTVVGELDRHLLRPLREVIWG-------HDENLLN
MLBr_00135|M.leprae_Br4923          GRELCSQLPVFAEEFDAVTGELDRHMRLPLRDVVWG-------ADAGLLD
MMAR_3798|M.marinum_M               AAELYRQHPGFATAVDECDAELRPYTGWSVRDVICQD------PDAPSLE
Mflv_0405|M.gilvum_PYR-GCK          ARELFDTEPVFADTVTRCADAVADLLPRPLLDVMFAGGREAGVPPTETLR
MAB_0939|M.abscessus_ATCC_1997      ARELFDAEPVFAETVTRCAEAVKDIVTRPLLEVMFATDRETGGKAGEALR
Mvan_0269|M.vanbaalenii_PYR-1       ARELFETEPVFADAVTRCADAVKDILPRPLLEVLFAADRESG----EALR
MSMEG_0408|M.smegmatis_MC2_155      ARELFDTQPVFAQTVRQCAEAVADMLPRPLLDVLFATDRETA----DLLQ
MAV_1763|M.avium_104                ARELFDAEPVFAETVTRCADAVDGLLPRPLTEVIFATDKDTGGEAGKTLR
TH_4621|M.thermoresistible__bu      GAELLATEQVFAAKIAEIEPLVARESGFSVTEAMTAS---------ETVT
                                    .  *      **  .      :      .: :.:              : 

Mb2074c|M.bovis_AF2122/97           STEFAQPALFAVEVALFRLLGSWGVRPDFVMGHSIGELSAAHVAGVLSLE
Rv2048c|M.tuberculosis_H37Rv        STEFAQPALFAVEVALFRLLGSWGVRPDFVMGHSIGELSAAHVAGVLSLE
MUL_2266|M.ulcerans_Agy99           TTEFAQPALFAVEVALYRLLESWGVRPDFVMGHSVGELSAAHVAGVLSLE
MLBr_00135|M.leprae_Br4923          STEFAQPALFAVEVALFAVLQHWGLQPDFVMGHSIGELAAAYVAGVLAPA
MMAR_3798|M.marinum_M               LVEVIQPVLFAVMIALAETLRGYGIVPDAVIGHSQGEIAAAYIAGALTLA
Mflv_0405|M.gilvum_PYR-GCK          HTSFAQPALFAVEMGLARLWQSWGIVPDVVLGHSVGQYAAACVAGVFSLE
MAB_0939|M.abscessus_ATCC_1997      HTSFAQPALFAVEMGLARLWQSWGIEPDVVLGHSVGQYAAACVAGVFSIE
Mvan_0269|M.vanbaalenii_PYR-1       HTSFAQPAIFAVEMGLARLWQSWGIEPDVVLGHSVGQYAAACVAGVFSLE
MSMEG_0408|M.smegmatis_MC2_155      HTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACVAGVFSLD
MAV_1763|M.avium_104                NTAFAQPALFAVEMGLARLWQSWGVEPDVVLGHSVGQYAAACVAGVFSLE
TH_4621|M.thermoresistible__bu      GIDRVQPTLFAIQVALAATMQSYGVRPGAVIGHSLGEVAAAVVAGALSLE
                                         **.:**: :.*      :.: *. *:*** *: :** :**.::  

Mb2074c|M.bovis_AF2122/97           NAAVLVAARGRLMQALPAGGAMVAVQAAEEEVRPLLS----AEVDIAAVN
Rv2048c|M.tuberculosis_H37Rv        NAAVLVAARGRLMQALPAGGAMVAVQAAEEEVRPLLS----AEVDIAAVN
MUL_2266|M.ulcerans_Agy99           NAAVLVAARGRLMQALPDGGAMIAVQATEQEVLPLLG----AQVSIATIN
MLBr_00135|M.leprae_Br4923          DAAMLVVARGRLMQSMPAGGTMWAVAASEDEVVSLLG----EGVGIAAIN
MMAR_3798|M.marinum_M               EAAKVVALRSAALAQLAGTGTMASVLLSPEELRPLLQP-WNTQISIAAIN
Mflv_0405|M.gilvum_PYR-GCK          DGARLMAERGRLFGSLPEGGRMVAVFADAKRVEQVAA--DFPRVSVGAYN
MAB_0939|M.abscessus_ATCC_1997      DGARLIAERGRLFGGLPAGGRMVAVFSDAKHVEQIAG--EFPRVSVGAYN
Mvan_0269|M.vanbaalenii_PYR-1       DGARLMAERGRMFGSLPEGGRMVAVFTDAKLVEEIAG--DFPRVSVGAYN
MSMEG_0408|M.smegmatis_MC2_155      DGARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAG--EFPRVSVGAYN
MAV_1763|M.avium_104                DGARLMAERGRLFGGLPDGGRMVAVFADAQYVEELAN--DCPRVSVAAYN
TH_4621|M.thermoresistible__bu      DGVKVICRRSRLCLRLAGAGAMAAIELPAQAVREFLAARGVDDVVLSVIA
                                    :.. ::  *.     :.  * * ::    . :  .        : :..  

Mb2074c|M.bovis_AF2122/97           GPASLVISGAQNAVAAVADQLRADGRRVHQLAVSHAFHSPLMDPMIDEFA
Rv2048c|M.tuberculosis_H37Rv        GPASLVISGAQNAVAAVADQLRADGRRVHQLAVSHAFHSPLMDPMIDEFA
MUL_2266|M.ulcerans_Agy99           GPASVVISGAQDAVSAVAEQLRADGRRVHRLAVSHAFHSPLMDPMIDEFA
MLBr_00135|M.leprae_Br4923          APESVVISGPQAAVSAIADKFAAQGRRVHQLAVSHAFHSPLMEPMLEEFV
MMAR_3798|M.marinum_M               GPAHTIISGDTTAVEQFIGTCEDGGVQIRPIAVDYASHSAHVERLREHLL
Mflv_0405|M.gilvum_PYR-GCK          GPN-TVLSGPGEDLEQIVGTFGEDGIRCTWLETSHAFHSELLDPVLDEFE
MAB_0939|M.abscessus_ATCC_1997      GPN-TVLSGPGEDLEQAVARFQEEGIRCTWLETSHAFHSELLDPILDEFE
Mvan_0269|M.vanbaalenii_PYR-1       GPN-TVLSGPGEDLEQIVDRFGDDGVRCTWLQTSHAFHSELLDPVLDEFE
MSMEG_0408|M.smegmatis_MC2_155      GPN-TVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDEFE
MAV_1763|M.avium_104                GPN-TVLSGPGADLEQIVARGASDGIRCSWLETSHAFHSELLDPVLDEFE
TH_4621|M.thermoresistible__bu      SPESTVIGGATDTVRELVAAWEAQGVMAREVAVDVASHSPQVDPILDELE
                                    .*   ::.*    :          *     : .. * **  :: : :.: 

Mb2074c|M.bovis_AF2122/97           AVAAGIAIGRPTIGVISNVTGQLAGDDFGS----AAYWRRHIRQAVRFAD
Rv2048c|M.tuberculosis_H37Rv        AVAAGIAIGRPTIGVISNVTGQLAGDDFGS----AAYWRRHIRQAVRFAD
MUL_2266|M.ulcerans_Agy99           TVAGELTVNAPTIGIISNLTGQLAGEDFGS----AAYWKRHVRDAVRFAD
MLBr_00135|M.leprae_Br4923          RVAAQVEVRKPQIGLVSNVTGELAGPDFGS----PQYWGEHVSRAVRFVD
MMAR_3798|M.marinum_M               HELADLNPQPARIPLYSTVASELSEHPLDTTAMDAEYWYRNLREPVEFYS
Mflv_0405|M.gilvum_PYR-GCK          SYAAQLQFAAPTLPLVCNRTGAVLTGQTSLD---AQYWRRHSRQPVQFAE
MAB_0939|M.abscessus_ATCC_1997      SYAAQVQFAAPTLPLVCNRTGAVLTAQTPID---GQYWRRHSRQPVQFAE
Mvan_0269|M.vanbaalenii_PYR-1       SYAAQFQFATPTLPLVCNRTGTVLTAQTPLD---AQYWRRHSRQPVQFAE
MSMEG_0408|M.smegmatis_MC2_155      AYAAQFQFAAPTLPLVCNRTGAVLTGQTPLD---AQYWRRHSRQPVQFAE
MAV_1763|M.avium_104                SYAAHLDFAVPTLPLVCNRTGTVLTTETPLD---ARYWRRHSRQPVQFAE
TH_4621|M.thermoresistible__bu      EILADLQPMTPTVPYYSATSYDPREKPVCD----ADYWVDNLRHEVRFAA
                                       . .    . :   .  :                **  :    *.*  

Mb2074c|M.bovis_AF2122/97           SVRFAQAAGGSRFLEVGPSGGLVASIEESLPDVAVT----TMSALRKDRP
Rv2048c|M.tuberculosis_H37Rv        SVRFAQAAGGSRFLEVGPSGGLVASIEESLPDVAVT----TMSALRKDRP
MUL_2266|M.ulcerans_Agy99           SIRFAQSAGAARFLEVGPSIGLTASIEEVLSDAAVTNPVATASALRKDRP
MLBr_00135|M.leprae_Br4923          SARHLQTLGATHFIESGPSSGLMGAIEQSLAPAEAV----VVSMMGKDRP
MMAR_3798|M.marinum_M               CVAQLLAHSERVFVELSPHPVLASALTDALADTGQLTQSAVVTTLRRDRP
Mflv_0405|M.gilvum_PYR-GCK          SVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHLAAPR--AIASLRKGVA
MAB_0939|M.abscessus_ATCC_1997      SVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHLAPPR--AIVSLRKGVE
Mvan_0269|M.vanbaalenii_PYR-1       SVRTVAALGCSVLMEIGPQPVLTGSAVQVWPEHLAAPR--AIVSLRKGVS
MSMEG_0408|M.smegmatis_MC2_155      SVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHMAAPR--AVASLRKGVA
MAV_1763|M.avium_104                SVRTVAALGCTVLMEIGPQPVLTGAAVQVWPEHLAAPR--AIVSLRKGVG
TH_4621|M.thermoresistible__bu      AVQAALEDGFRVFGELSPHPLLTRAVEQTARGLDMPVA--ALPAMRREQE
                                    .       .   : * .*   *  :  :            .   : :   

Mb2074c|M.bovis_AF2122/97           EPATLTNAVAQGFVTGMDLDWRAVVG--EAQFVELPTYAFQRRRFWLS-G
Rv2048c|M.tuberculosis_H37Rv        EPATLTNAVAQGFVTGMDLDWRAVVG--EAQFVELPTYAFQRRRFWLS-G
MUL_2266|M.ulcerans_Agy99           EPVSLVSALAGVFVAGTAVDWRAVVG--QSHFVELPTYAFERRRFWLS-G
MLBr_00135|M.leprae_Br4923          ELASVLGAAGQLFATGMPVEWPAVFAGSSRRRVTLPTYAFQRRRFWETPG
MMAR_3798|M.marinum_M               DMDMVASAIANLHVHGHSPSWQKIYP--GATTVELPTYAFQRRHYWLAAP
Mflv_0405|M.gilvum_PYR-GCK          DRRQIADALAAAYIGGHKPDFAALHE-QRGVRLELPTYPFQRRRFWPKSA
MAB_0939|M.abscessus_ATCC_1997      DRRQIADALASAYVSGHRPNFAALQR-HPRRTVELPTYPFQRRRFWPKSS
Mvan_0269|M.vanbaalenii_PYR-1       DRRQITEALAAAYVGGHRPDFGALYR-RPGRAVALPTYPFQRRRFWPKTS
MSMEG_0408|M.smegmatis_MC2_155      DRRQIADALASAYVGGHRPDFAAVHR-QPRRPVELPTYPFQRRRFWPKAS
MAV_1763|M.avium_104                DRRQIAEGLAAAYVSGHRPEFAALHR-RPRRKLELPTYPFQRRRFWPKAS
TH_4621|M.thermoresistible__bu      MPHGVRTMVGDLFAAGAAVDFAALYP--SGRLVDAPLPTWTRRKLVLSRE
                                        :    .  .  *   .:  :        :  *  .: **:      

Mb2074c|M.bovis_AF2122/97           DGVAADAAS-----------------------------------------
Rv2048c|M.tuberculosis_H37Rv        DGVAADAAG-----------------------------------------
MUL_2266|M.ulcerans_Agy99           DAVPADAAG-----------------------------------------
MLBr_00135|M.leprae_Br4923          TDGTASVSG-----------------------------------------
MMAR_3798|M.marinum_M               TPTPATVSDPAEVALWDAVNDDAVDTVARVLRIDNAQSMVSLGPMVRALR
Mflv_0405|M.gilvum_PYR-GCK          GMA-IDGRV-----------------------------------------
MAB_0939|M.abscessus_ATCC_1997      GTA-IEG-------------------------------------------
Mvan_0269|M.vanbaalenii_PYR-1       GIT-TDG-------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      SIA-VDG-------------------------------------------
MAV_1763|M.avium_104                GIAGIDG-------------------------------------------
TH_4621|M.thermoresistible__bu      NGEQQTRGG-----------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           -----LG-------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        -----LG-------------------------------------------
MUL_2266|M.ulcerans_Agy99           -----LG-------------------------------------------
MLBr_00135|M.leprae_Br4923          -----LG-------------------------------------------
MMAR_3798|M.marinum_M               EWRKELGDRSVVGQLRYQVGWRNVTPNTFPQTRQRWLVLTLPEQSDDVWV
Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
Mvan_0269|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
MAV_1763|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               AGFSARFADSVAMLAIDPHMFDRNSLAALLADEATRNKCDGVVSFMALRE
Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
Mvan_0269|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
MAV_1763|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           -----------------------------------------------LAA
Rv2048c|M.tuberculosis_H37Rv        -----------------------------------------------LAA
MUL_2266|M.ulcerans_Agy99           -----------------------------------------------LQA
MLBr_00135|M.leprae_Br4923          -----------------------------------------------LGS
MMAR_3798|M.marinum_M               RTHQDFRGISTALLSTLHITQAYGDSGLDLPLWVITQGGAQVNPDEDLTP
Mflv_0405|M.gilvum_PYR-GCK          -----------------------------------------------GAS
MAB_0939|M.abscessus_ATCC_1997      -----------------------------------------------GGG
Mvan_0269|M.vanbaalenii_PYR-1       -------------------------------------------------P
MSMEG_0408|M.smegmatis_MC2_155      ------------------------------------------------GT
MAV_1763|M.avium_104                -----------------------------------------------QGA
TH_4621|M.thermoresistible__bu      -----------------------------------------------CTI
                                                                                      

Mb2074c|M.bovis_AF2122/97           SEHALLG--------------AVIDLPASGG-------------------
Rv2048c|M.tuberculosis_H37Rv        SEHALLG--------------AVIDLPASGG-------------------
MUL_2266|M.ulcerans_Agy99           GEHALLG--------------AVVELPASGG-------------------
MLBr_00135|M.leprae_Br4923          TEHALLG--------------AVVERPDSGG-------------------
MMAR_3798|M.marinum_M               SQSAVWGLGQSACLEHPTWWGGLVDLPVSPAPQDFNRLQAILTCQQSEDQ
Mflv_0405|M.gilvum_PYR-GCK          AGSGILG--------------SGKDLASGDS-------------------
MAB_0939|M.abscessus_ATCC_1997      LPSGILG--------------RGEDLASGDS-------------------
Mvan_0269|M.vanbaalenii_PYR-1       AVSGILG--------------SAKDLASGDT-------------------
MSMEG_0408|M.smegmatis_MC2_155      AASGILG--------------SGKDLASGDT-------------------
MAV_1763|M.avium_104                AASGLLG--------------SAKELASGDS-------------------
TH_4621|M.thermoresistible__bu      TVHPLLG--------------THVRLPEEPER------------------
                                        : *                   .                       

Mb2074c|M.bovis_AF2122/97           ----------------------------------VVLTGRLSPSVQGWLA
Rv2048c|M.tuberculosis_H37Rv        ----------------------------------VVLTGRLSPSVQGWLA
MUL_2266|M.ulcerans_Agy99           ----------------------------------VVLTGRLSLAAQGWLA
MLBr_00135|M.leprae_Br4923          ----------------------------------VVLTGRLSLANQPWLA
MMAR_3798|M.marinum_M               LAIRAAGVSARRLHKASLPQDRMRTWKISGTALVTGVTGHLGQHIARWLA
Mflv_0405|M.gilvum_PYR-GCK          -----------------------------------VYTSRLSVKTQPWLS
MAB_0939|M.abscessus_ATCC_1997      -----------------------------------VYISRLSVRSQPWLS
Mvan_0269|M.vanbaalenii_PYR-1       -----------------------------------VYTSRWSVRSQPWLA
MSMEG_0408|M.smegmatis_MC2_155      -----------------------------------IYTSRLSVKSQPWLA
MAV_1763|M.avium_104                -----------------------------------VYTSRLSVKSQPWLA
TH_4621|M.thermoresistible__bu      ----------------------------------HVWQADLGTGAQPWLA
                                                                          .  .     **:

Mb2074c|M.bovis_AF2122/97           DHSVAGVTIFP---------------------------------------
Rv2048c|M.tuberculosis_H37Rv        DHSVAGVTIFP---------------------------------------
MUL_2266|M.ulcerans_Agy99           DHAVGGVVIFP---------------------------------------
MLBr_00135|M.leprae_Br4923          DHVIGGVVLFP---------------------------------------
MMAR_3798|M.marinum_M               QAGASHLVLLSRTAAEHPQVAELEKELNSAGITTTSISVDVTDRDALAAV
Mflv_0405|M.gilvum_PYR-GCK          DHVIYGTVVVP---------------------------------------
MAB_0939|M.abscessus_ATCC_1997      DHVIYGTVVVP---------------------------------------
Mvan_0269|M.vanbaalenii_PYR-1       DHVIYGTVVVP---------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      DHVIYGTVVVP---------------------------------------
MAV_1763|M.avium_104                DHVIYGTVVVP---------------------------------------
TH_4621|M.thermoresistible__bu      DHQIHTVAALP---------------------------------------
                                    :      . ..                                       

Mb2074c|M.bovis_AF2122/97           ------GAGFVELAIRAGDEVGCGVVDELTLAAPLVLPASGSVAVQVVVN
Rv2048c|M.tuberculosis_H37Rv        ------GAGFVELAIRAGDEVGCGVVDESTLAAPLVLPASGSVAVQVVVN
MUL_2266|M.ulcerans_Agy99           ------GAGFVELAIRAGDEVGCRVVDELTLAAPLVLPSGGSVAVQVVVG
MLBr_00135|M.leprae_Br4923          ------GAGFVELVIRAGDEVGCAGVEELVLAAPLVLHPGSGVQVQVVVA
MMAR_3798|M.marinum_M               VAETRIEHGPIHTVVHAAAHIGLVTTAETTIDEFIKSFAAKALGAENLIA
Mflv_0405|M.gilvum_PYR-GCK          --------GATYAAMALAAVGTPAHAKDVFFYEPIILPEKSSREVQLTVH
MAB_0939|M.abscessus_ATCC_1997      --------GATYAAMALAAVGTPARAKDVFFYEPIILPEKSSREVQLTLH
Mvan_0269|M.vanbaalenii_PYR-1       --------GATYAAMALAAVGTPARVKDVFFYEPIILPEKASREVQLTLH
MSMEG_0408|M.smegmatis_MC2_155      --------GATYAAMALAAVGTPARLKDVFFYEPIILPEKASREVQLTLH
MAV_1763|M.avium_104                --------GATYAAMALAAVGPPARVQNVYFYEPIILPDKASREVQLSLH
TH_4621|M.thermoresistible__bu      --------GAAYCEMALAAAREVIDSDGVEVRDVRFEQMLLLDEQTEVSA
                                            *     :  .            .                   

Mb2074c|M.bovis_AF2122/97           GPDESGVRGVSVYSR-GDVGTG-WVLHAEGALRA------------GSAE
Rv2048c|M.tuberculosis_H37Rv        GPDESGVRGVSVYSR-GDVGTG-WVLHAEGALRA------------GSAE
MUL_2266|M.ulcerans_Agy99           SPDDSGARAVSVYSR-GDAGSD-WVLHAEGSLGS------------GSPE
MLBr_00135|M.leprae_Br4923          AADESSRRAVSVYSR-GDQSHGGWLLNAEGLLEV------------DAAE
MMAR_3798|M.marinum_M               VLEDQPPQTFIMFSS-AAATWGGTRQGAYAAANAYIEALVTRLRGRGCRA
Mflv_0405|M.gilvum_PYR-GCK          PSVDGE-SKFQVHSRPYGERGAEWALNAEGVVASGVGD---SPAAAGDLE
MAB_0939|M.abscessus_ATCC_1997      PLEDGSGSKFQVHSRPYGERDVDWSLNAEGTVVTGIGDDAEPAPEAAEPA
Mvan_0269|M.vanbaalenii_PYR-1       PSEDGG-QKFQVHSREYGERGTEWSLNAEGTVASGVDE-----NPQAEPS
MSMEG_0408|M.smegmatis_MC2_155      PADGGSVLSFQIHSRPYGERGADWSLNAEGTVDTAGSD---PDAAADEQS
MAV_1763|M.avium_104                PLQEGG-WSFRVDSRPYGVPDAEWSLNADGTVVAGIED-----EPAADPA
TH_4621|M.thermoresistible__bu      VASAVEPGTLEFAVETAKDGEHERRATAVLGAADDTEP--------PQAH
                                             . .               *                      

Mb2074c|M.bovis_AF2122/97           PTADLAMWPPAGAVPVEVADGYQQLAERGYG-------------------
Rv2048c|M.tuberculosis_H37Rv        PTADLAMWPPAGAVPVEVADGYQQLAERGYG-------------------
MUL_2266|M.ulcerans_Agy99           PATDLSTWPPVGAVEVENADGYQQLAERGYG-------------------
MLBr_00135|M.leprae_Br4923          ATVDLSLWPPEGAESVDISDAYPQLAERGYA-------------------
MMAR_3798|M.marinum_M               IAPAWGAWTDDRTTTQEVVGYFSRIGLNQISPDIAFAALQQSLDVDDTLI
Mflv_0405|M.gilvum_PYR-GCK          DPVDEAIERLNRMRPQELFETFADLELAWGP-------------------
MAB_0939|M.abscessus_ATCC_1997      EPVDAAIERMERMRPMELFEIFADLELAWGP-------------------
Mvan_0269|M.vanbaalenii_PYR-1       GPVDEAIERLNRMRPQDLFETFADMELAWGP-------------------
MSMEG_0408|M.smegmatis_MC2_155      DPVDEVIERLERMRPQDLFETFADLELAWGP-------------------
MAV_1763|M.avium_104                DHIDAVIERLDRNRPQLLFDSFAESELEWGT-------------------
TH_4621|M.thermoresistible__bu      DIDALLAEHPTRIEGDELRQWFDQRGVQFGP-------------------
                                                         :                            

Mb2074c|M.bovis_AF2122/97           -----YGPAFRGLTAMWRRGDEVFAEVALPADAGVSVTGFGVH-------
Rv2048c|M.tuberculosis_H37Rv        -----YGPAFRGLTAMWRRGDEVFAEVALPADAGVSVTGFGVH-------
MUL_2266|M.ulcerans_Agy99           -----YGPAFRGLNAMWRRGDEVFAEVALPADAGVSVSGFGIH-------
MLBr_00135|M.leprae_Br4923          -----YGPAFQGLVAIWRRGSELFAEVVAPT--GVVVDGMGMH-------
MMAR_3798|M.marinum_M               TIADVDWSQFRDVFTTTGRAHALLAELGTSQPQTAEIPAIAENSHFAAQL
Mflv_0405|M.gilvum_PYR-GCK          -------TWSGSLKSLWLGEGEAIGDILVGAELAEQLGTEPMH-------
MAB_0939|M.abscessus_ATCC_1997      -------TWSGSLKSLWLGEGEAIGDVLVGEELAEQLGTEPMH-------
Mvan_0269|M.vanbaalenii_PYR-1       -------TWSGSLKSLWLGEGEAIGDILVGEELAEQLGTEPMH-------
MSMEG_0408|M.smegmatis_MC2_155      -------TWSGSLKSLWLGDGEAVGDILVGAELAEQLGSEPMH-------
MAV_1763|M.avium_104                -------TWSTSLKSLWMGDGEAVGDVTVGDELAEHLGTEPMH-------
TH_4621|M.thermoresistible__bu      -----AFTGLTAARIPEGTVTSVLAEVGLPGQIRSQQAPYGIH-------
                                           .               ..::               :       

Mb2074c|M.bovis_AF2122/97           ----------------------------PVLLDAALHAVVLSAESAERG-
Rv2048c|M.tuberculosis_H37Rv        ----------------------------PVLLDAALHAVVLSAESAERG-
MUL_2266|M.ulcerans_Agy99           ----------------------------PVMLDAALHAVILASDGADDFG
MLBr_00135|M.leprae_Br4923          ----------------------------PALLDAVLHALGLAIENTQAT-
MMAR_3798|M.marinum_M               AKQAPQQQLATLIGLVTNVTAAVLAHPDPAVLDPDLSFKDLGIDSLSALE
Mflv_0405|M.gilvum_PYR-GCK          ----------------------------PVLMDLCTGVAFPAFPALLAAE
MAB_0939|M.abscessus_ATCC_1997      ----------------------------PVLMDLCTGVAFPAFPALLAAE
Mvan_0269|M.vanbaalenii_PYR-1       ----------------------------PVLMDLCTGVAFPAFPALLAAE
MSMEG_0408|M.smegmatis_MC2_155      ----------------------------PVLMDLCTGVAFPAFPALLAAE
MAV_1763|M.avium_104                ----------------------------PVLLDLCTGVVFPAFPALLAAE
TH_4621|M.thermoresistible__bu      ----------------------------PALLDACFQSVAAHPDVQGAG-
                                                                *.::*                 

Mb2074c|M.bovis_AF2122/97           --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           VP------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               LRNTLTRDTGLTLPATVVFDHPTPTAVAEHLLGLLSGVTGPTLAVVPTRV
Mflv_0405|M.gilvum_PYR-GCK          QG------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      QG------------------------------------------------
Mvan_0269|M.vanbaalenii_PYR-1       QG------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      QG------------------------------------------------
MAV_1763|M.avium_104                QG------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               GVDVPVAVVGMACRLPGGIESAAGLWDVVSNGIDVMSGFPLDRGWDVAGL
Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
Mvan_0269|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
MAV_1763|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           ------------------------------------------QGSVLVPF
Rv2048c|M.tuberculosis_H37Rv        ------------------------------------------QGSVLVPF
MUL_2266|M.ulcerans_Agy99           ------------------------------------------EGSVLVPF
MLBr_00135|M.leprae_Br4923          -------------------------------------------TEMRLPF
MMAR_3798|M.marinum_M               FDPDPDAEGKTYTRYGGFVADVAGFDAEFFGISAREAITMDPQQRVLLEV
Mflv_0405|M.gilvum_PYR-GCK          ------------------------------------------VNDLYLPL
MAB_0939|M.abscessus_ATCC_1997      ------------------------------------------VNDLFLPL
Mvan_0269|M.vanbaalenii_PYR-1       ------------------------------------------VSDLFLPL
MSMEG_0408|M.smegmatis_MC2_155      ------------------------------------------VNDLFLPL
MAV_1763|M.avium_104                ------------------------------------------FNDLLLPL
TH_4621|M.thermoresistible__bu      -------------------------------------------SGLLLPL
                                                                                 : : .

Mb2074c|M.bovis_AF2122/97           SWQGVSLHAAGASAVRAR------------------------IAPVGPSA
Rv2048c|M.tuberculosis_H37Rv        SWQGVSLHAAGASAVRAR------------------------IAPVGPSA
MUL_2266|M.ulcerans_Agy99           AWQGVTLHAAGASAVRAR------------------------IAPAGPSA
MLBr_00135|M.leprae_Br4923          CWRGVSLHAGGAGRVRAR------------------------FTSAGADA
MMAR_3798|M.marinum_M               CWQALEHAGIDPTTLEGSDTGVFVGIGAQSYVSGHSGVEGYALTGASASV
Mflv_0405|M.gilvum_PYR-GCK          RYGQVSLQEKMPRRFYCRATWHEAPLDSETQVFDLEYLDRDGRHLGGVRE
MAB_0939|M.abscessus_ATCC_1997      RYGQVTLKEKMPRRFYCRARWHESPLDSETQVFDLDYLDRDGRHLGGIRE
Mvan_0269|M.vanbaalenii_PYR-1       RYGQVTLRDKMPRRFYCRATWHTSELDSETQVFDLDFLDRDGRHLGGIRE
MSMEG_0408|M.smegmatis_MC2_155      RYGQVTLAEKMPRRFYCRARWHRSALDSETQVFELEFVDLGGRALGGIRE
MAV_1763|M.avium_104                RYGQVSLREKMPRRFYCRGKWRPSALDSETQVFDIDFIDRDGRHLGGIRE
TH_4621|M.thermoresistible__bu      GVRRLQAFGPTRGARYCYARVTDADGSKAEADLDVLDEHGNVLLRVQGLL
                                        :                                             

Mb2074c|M.bovis_AF2122/97           VSIELADGLGLP----------VLSVASMLARPVTDQQLR----------
Rv2048c|M.tuberculosis_H37Rv        VSIELADGLGLP----------VLSVASMLARPVTDQQLR----------
MUL_2266|M.ulcerans_Agy99           VSIELSDGLGLP----------VLSVASMLARPVTDQQLR----------
MLBr_00135|M.leprae_Br4923          IAVDIADSAGLP----------VLTVRSLVTRAMTAEQLR----------
MMAR_3798|M.marinum_M               ASGRVAYVLGLQGPA---ITVDTACSSSLVATHLACQSLRNGESSLALAG
Mflv_0405|M.gilvum_PYR-GCK          FTVKRAPREALLRG--------LGGDATRLLYTLGWHEVPVP--------
MAB_0939|M.abscessus_ATCC_1997      FTVKRAPREALLRG--------LGGDATRLLYTLGWHEVAVPPVA-----
Mvan_0269|M.vanbaalenii_PYR-1       FTVKRAPREALLRG--------LGGDATRLLYTLGWHEVPAP--------
MSMEG_0408|M.smegmatis_MC2_155      FTVKRAPREALLRG--------LGGDATRLLYTLGWHEVPPP--------
MAV_1763|M.avium_104                FTVKRAPREALLRG--------LGGDATRLLYTLGWHEVPPQP-------
TH_4621|M.thermoresistible__bu      MGGAAADGDDRDRVLGERLLTIEWQRRDLPEADSAAG-------------
                                         :                                            

Mb2074c|M.bovis_AF2122/97           ------------------------------AAVSSSG---------PDRL
Rv2048c|M.tuberculosis_H37Rv        ------------------------------AAVSSSG---------PDRL
MUL_2266|M.ulcerans_Agy99           ------------------------------AAVSGAG---------PDRL
MLBr_00135|M.leprae_Br4923          ------------------------------TAVTAAGG------ALEQGP
MMAR_3798|M.marinum_M               GATIMATPTPFIEFARQRGLAADGRCKAFAAAADGTGWGEGAAVLVLERL
Mflv_0405|M.gilvum_PYR-GCK          ---------------------------ESGDGAAPQGT------WLIGGF
MAB_0939|M.abscessus_ATCC_1997      --------------------------GEGEESAASIGT------WLIAGF
Mvan_0269|M.vanbaalenii_PYR-1       ----------------------------ASGDAALNGN------WLIAGF
MSMEG_0408|M.smegmatis_MC2_155      -----------------------------PSADDAVGT------WLIAGF
MAV_1763|M.avium_104                ---------------------------SNDGVANPSGT------WLIAGF
TH_4621|M.thermoresistible__bu      --------------------------KWLLVSTSATADVS-----ATRLS
                                                                        .             

Mb2074c|M.bovis_AF2122/97           FEVTWSPQPSAAVEP---LPVCAWGTTEDS------AAVVFESVPLAG--
Rv2048c|M.tuberculosis_H37Rv        FEVTWSPQPSAAVEP---LPVCAWGTTEDS------AAVVFESVPLAG--
MUL_2266|M.ulcerans_Agy99           FGVDWTAQPSAELQP---VPVRIWGTVESEGDDDPGASVVFESVPQAG--
MLBr_00135|M.leprae_Br4923          MDLVWSPIPLSSDGHGGGLPSVVSWADYCAGRGNDTGVVVWEFGSASAGA
MMAR_3798|M.marinum_M               SDARRNRHPVLAVIAGSAVNQDGASNGLSAPNGPAQQRVISQALANAGLP
Mflv_0405|M.gilvum_PYR-GCK          DELAVSVPGCIPADR-TNPESLRQLLTDAHGRGLPFSGVVWRAARSDGDE
MAB_0939|M.abscessus_ATCC_1997      DELAAKVPGCIPLNRETDPELLGEVLVAAKERGVPFSGVVWRAAGPGATE
Mvan_0269|M.vanbaalenii_PYR-1       DELAAGVPGCIPFDRSTDPEPLGQLLAQAHERGIGFSGVVWRAAAPSADE
MSMEG_0408|M.smegmatis_MC2_155      DELAAKVPGCVPIDRNTDLQVLGEVLSQAHARGAGFSGVVWRCATPGRKE
MAV_1763|M.avium_104                DELGAQLPGCIPFDRNTDPESFGQLLARAEDRGGPVTGIVWRATQSGGRE
TH_4621|M.thermoresistible__bu      DALKQAGAESTSMCWPQQADHADNVDRFRAGIADGVTGVVVLTGPKNGNP
                                                                          ::          

Mb2074c|M.bovis_AF2122/97           ----DVVAGVYAATSS----------------------------------
Rv2048c|M.tuberculosis_H37Rv        ----DVVAGVYAATSS----------------------------------
MUL_2266|M.ulcerans_Agy99           ----EVVAGVYAATAA----------------------------------
MLBr_00135|M.leprae_Br4923          QAPVDSVAAVYSATHA----------------------------------
MMAR_3798|M.marinum_M               FTHVDVVEAHGTGTTLGDPIEAGALIATYGTHRDPEHPLWLGSVKSNIGH
Mflv_0405|M.gilvum_PYR-GCK          S--DAEVAARLEAEIAE---------------------------------
MAB_0939|M.abscessus_ATCC_1997      S--TTESAARLEGEIAH---------------------------------
Mvan_0269|M.vanbaalenii_PYR-1       S--STAMAARIETEIAD---------------------------------
MSMEG_0408|M.smegmatis_MC2_155      SGSASAESARLEAEITN---------------------------------
MAV_1763|M.avium_104                S--SAESVARLETEIAG---------------------------------
TH_4621|M.thermoresistible__bu      DDAAARRGSDYVRHLVR---------------------------------
                                            .                                         

Mb2074c|M.bovis_AF2122/97           -------------------------------------------VLDVLQS
Rv2048c|M.tuberculosis_H37Rv        -------------------------------------------VLDVLQS
MUL_2266|M.ulcerans_Agy99           -------------------------------------------VLEVLRS
MLBr_00135|M.leprae_Br4923          -------------------------------------------ALQVLQF
MMAR_3798|M.marinum_M               TQHAAGAAGLIKMIQALNHAVLPATLHIDQPSPHIDWSTDTVRLLTEATP
Mflv_0405|M.gilvum_PYR-GCK          -------------------------------------------LLGAVHT
MAB_0939|M.abscessus_ATCC_1997      -------------------------------------------LLSAVHT
Mvan_0269|M.vanbaalenii_PYR-1       -------------------------------------------LLSAVHT
MSMEG_0408|M.smegmatis_MC2_155      -------------------------------------------LLSAVHA
MAV_1763|M.avium_104                -------------------------------------------LLTAVHA
TH_4621|M.thermoresistible__bu      -------------------------------------------ITRELAE
                                                                                      

Mb2074c|M.bovis_AF2122/97           WLT-----RDGAGVLVVMTRGAVALPGEDVTDLAGAAVWGLVRSAQTEHP
Rv2048c|M.tuberculosis_H37Rv        WLT-----RDGAGVLVVMTRGAVALPGEDVTDLAGAAVWGLVRSAQTEHP
MUL_2266|M.ulcerans_Agy99           WLS-----RDGAGQLIITTRGAVALPDEDVTDLAGSAVWGLVRSAQTEHP
MLBr_00135|M.leprae_Br4923          WFG-----QDRAGTLVVLTRGAVGLVGEGISDLAAAAVWGMVRSAQSEHS
MMAR_3798|M.marinum_M               WPE-----TEHLRTGAVSAFGVSGTNAHLIVQQAPPEVFESVPEPETARP
Mflv_0405|M.gilvum_PYR-GCK          VQ---GGEVKLPGGLWIVTERAVATESGEPVDPVQAALWGFGRTAINEEP
MAB_0939|M.abscessus_ATCC_1997      VQNSAQNGVKLPGGLWIVTERAVATESGEPVDPVQAALWGFGRTTINEEP
Mvan_0269|M.vanbaalenii_PYR-1       VQN---GAVKLPGGLWIVTERAVATESGEPVDPVQAALWGFGRTTINEEP
MSMEG_0408|M.smegmatis_MC2_155      AQG---PSVKLPGGLWIVTEHGVACESGEPVDPVQAALWGFGRTTINEEP
MAV_1763|M.avium_104                LQNADGSAVKLPGGLWIVTERGVATESGEPVDPVQAALWGLGRTIVNEEP
TH_4621|M.thermoresistible__bu      IDG-------DAPRLFVVTRGAQAVLPQDRPNLEQAGLRGLLRVIGAEHP
                                                    : :    .       :   . :          ..

Mb2074c|M.bovis_AF2122/97           G-------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        G-------------------------------------------------
MUL_2266|M.ulcerans_Agy99           G-------------------------------------------------
MLBr_00135|M.leprae_Br4923          G-------------------------------------------------
MMAR_3798|M.marinum_M               SGQPLLRIWPVSAHTPAALTAQAERLSEYLTRHEDLSLTDLAYSLACTRT
Mflv_0405|M.gilvum_PYR-GCK          ALR-----------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      ALR-----------------------------------------------
Mvan_0269|M.vanbaalenii_PYR-1       ALR-----------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      ALH-----------------------------------------------
MAV_1763|M.avium_104                ALR-----------------------------------------------
TH_4621|M.thermoresistible__bu      HLR-----------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               HHPYRAAVTVPVDTSNPGHDLAAALRALAANQPHPYVTCHHYRARQPSKT
Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
Mvan_0269|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
MAV_1763|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               VFVFPGQGGQYPAMAAELYRQHPGFATAVDECDAELRPYTGWSVRDVICQ
Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
Mvan_0269|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
MAV_1763|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           -----------------------------------RIVLVDSDAPLDDSA
Rv2048c|M.tuberculosis_H37Rv        -----------------------------------RIVLVDSDAPLDDSA
MUL_2266|M.ulcerans_Agy99           -----------------------------------RIVLVDTDAQLDEHA
MLBr_00135|M.leprae_Br4923          -----------------------------------KIVLIDTDSAVD---
MMAR_3798|M.marinum_M               DPDAPSLELVEVIQPVLFAVMIALAETLRGYGIVPDAVIGHSQGEIAAAY
Mflv_0405|M.gilvum_PYR-GCK          -----------------------------------CRLVDCDGSPQAVQA
MAB_0939|M.abscessus_ATCC_1997      -----------------------------------AKLVDGDGSPEAVQA
Mvan_0269|M.vanbaalenii_PYR-1       -----------------------------------CRLVDVDGSPEAVLA
MSMEG_0408|M.smegmatis_MC2_155      -----------------------------------CRLVDCDGSSEAVDL
MAV_1763|M.avium_104                -----------------------------------CRLVDSDGSEQAVRS
TH_4621|M.thermoresistible__bu      -----------------------------------TTQIDIADDADLDRV
                                                                          :           

Mb2074c|M.bovis_AF2122/97           LAAVVTTG---EPQVLWRRGEVYTARVHGSRAVGGLLVPPSDR-------
Rv2048c|M.tuberculosis_H37Rv        LAAVVTTG---EPQVLWRRGEVYTARVHGSRAVGGLLVPPSDR-------
MUL_2266|M.ulcerans_Agy99           VAAVLAAG---EPQVLWRNGEVYTARVHGSRAVAGLLVPPGDG-------
MLBr_00135|M.leprae_Br4923          VAVLADLG---ESQLLVRCNTVHAARLS--PAPQLLALPVGES-------
MMAR_3798|M.marinum_M               IAGALTLA---EAAKVVALRSAALAQLAGTGTMASVLLSPEELRPL----
Mflv_0405|M.gilvum_PYR-GCK          LAALLSTP-VDEPELAVRQGKLLASRLLPWSRSGHLTVPRGGD-------
MAB_0939|M.abscessus_ATCC_1997      LARLLVTP-VDEPEIAVRQGKLLASRLLPWSRTGHLTVPRGSD-------
Mvan_0269|M.vanbaalenii_PYR-1       LAGLLAAP-VDEPELAVRQGKLLASRLLPWARSGHLTVPRSAD-------
MSMEG_0408|M.smegmatis_MC2_155      LAALLAAPGIQEPEIAVRQGKLLASRLLPWARSGHLTLPRGGD-------
MAV_1763|M.avium_104                LAGLLGAP-LDEPELAVRQGKLLASRLLPWARSGHLAVPRGTD-------
TH_4621|M.thermoresistible__bu      AVQLLGGG--AEDETAWRDGQWYTARLSLSPLRPEERKQAVVDCERDGMR
                                     .         *            :::                       

Mb2074c|M.bovis_AF2122/97           ------PWRLAMSTA---------------------GTFEN---------
Rv2048c|M.tuberculosis_H37Rv        ------PWRLAMSTA---------------------GTFEN---------
MUL_2266|M.ulcerans_Agy99           ------PWRLGMSTA---------------------GTFEN---------
MLBr_00135|M.leprae_Br4923          ------MWRLAADGG---------------------GTLED---------
MMAR_3798|M.marinum_M               ----LQPWNTQISIAAINGPAHTIISGDTTAVEQFIGTCEDGGVQIRPIA
Mflv_0405|M.gilvum_PYR-GCK          -------YVLAPTER---------------------GAIDN---------
MAB_0939|M.abscessus_ATCC_1997      -------YVLAPTER---------------------GAIDN---------
Mvan_0269|M.vanbaalenii_PYR-1       -------YVLAPTER---------------------GAIDN---------
MSMEG_0408|M.smegmatis_MC2_155      -------FVLAPTER---------------------GAIDN---------
MAV_1763|M.avium_104                -------YVLAPTER---------------------GAIDN---------
TH_4621|M.thermoresistible__bu      LEIRTP------------------------------GDLET---------
                                                                        *  :          

Mb2074c|M.bovis_AF2122/97           --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               VDYASHSAHVERLREHLLHELADLNPQPARIPLYSTVASELSEHPLDTTA
Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
Mvan_0269|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
MAV_1763|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           -------------------------------LRLELIPDADAPLG---PG
Rv2048c|M.tuberculosis_H37Rv        -------------------------------LRLELIPDADAPLG---PG
MUL_2266|M.ulcerans_Agy99           -------------------------------LRLEPIPDADAALQ---PG
MLBr_00135|M.leprae_Br4923          -------------------------------LVIQPCPEVQAPLQ---AG
MMAR_3798|M.marinum_M               MDAEYWYRNLREPVEFYSCVAQLLAHSERVFVELSPHPVLASALTDALAD
Mflv_0405|M.gilvum_PYR-GCK          ---------------------------------LRLTDSEVPPPA---EG
MAB_0939|M.abscessus_ATCC_1997      ---------------------------------LRITEKEVPAPD---EG
Mvan_0269|M.vanbaalenii_PYR-1       ---------------------------------LRLTETDVAPPA---EG
MSMEG_0408|M.smegmatis_MC2_155      ---------------------------------LRLTETDVPEPD---EG
MAV_1763|M.avium_104                ---------------------------------LRLIEQEAPPPA---EG
TH_4621|M.thermoresistible__bu      ---------------------------------MELAAFDRVPPG---PG
                                                                     :               .

Mb2074c|M.bovis_AF2122/97           QVRVAVSAIAANFR--------DVMIALG-------------LYP-----
Rv2048c|M.tuberculosis_H37Rv        QVRVAVSAIAANFR--------DVMIALG-------------LYP-----
MUL_2266|M.ulcerans_Agy99           HVRVALSAMAANFR--------DVMIALG-------------LYP-----
MLBr_00135|M.leprae_Br4923          HMRVAVAAVGVNFR--------DVVAALG-------------MYP-----
MMAR_3798|M.marinum_M               TGQLTQSAVVTTLRRDRPDM-DMVASAIANLHVHGHSPSWQKIYPGATTV
Mflv_0405|M.gilvum_PYR-GCK          YVQVRVEAAGLNFRDVLNVLG---------------------LYP-----
MAB_0939|M.abscessus_ATCC_1997      YVQVRVEAAGLNFRDVLNVLG---------------------LYP-----
Mvan_0269|M.vanbaalenii_PYR-1       YVQVRVEAAGLNFRDVLNVLG---------------------LYP-----
MSMEG_0408|M.smegmatis_MC2_155      YVQVRVEAAGLNFRDVLNVLG---------------------LYP-----
MAV_1763|M.avium_104                CVQVRVEAGGLNFREVLNVLG---------------------LYP-----
TH_4621|M.thermoresistible__bu      QIEVAVTASSINFADVLIAFG---------------------RYPTFD--
                                      .:   *   .:                              **     

Mb2074c|M.bovis_AF2122/97           --------------DPDAVMGVEACG----------VVIETSLNKGSFAV
Rv2048c|M.tuberculosis_H37Rv        --------------DPDAVMGVEACG----------VVIETSLNKGSFAV
MUL_2266|M.ulcerans_Agy99           --------------DPDAAMGVEGAG----------VVVETASPDGRFAV
MLBr_00135|M.leprae_Br4923          --------------GQAPPLGAEGAG----------VVIEIGPEVTGVAV
MMAR_3798|M.marinum_M               ELPTYPFQHRRYWLDPAPRADVSAAGLDQPEHPLLAAVTELADQDQIVLS
Mflv_0405|M.gilvum_PYR-GCK          --------------GDPGPIGGDFAG----------TVTQLGEGVTGLDV
MAB_0939|M.abscessus_ATCC_1997      --------------GDPGPIGGDFAG----------IVTQLGEGVTGVEV
Mvan_0269|M.vanbaalenii_PYR-1       --------------GDPGPIGGDFAG----------TVTQLGSGVTGLEV
MSMEG_0408|M.smegmatis_MC2_155      --------------GDPGPIGGDFAG----------TVTQLGAGVSGLEI
MAV_1763|M.avium_104                --------------GDPGPLGGDFAG----------TVTQLGSGVTGLEV
TH_4621|M.thermoresistible__bu      --------------GRRPQLGTDFAG----------VVTAVGPDVTSHRV
                                                  .     . . .*           *   .        

Mb2074c|M.bovis_AF2122/97           G------------------------DRVMGLFPEGTGTVASTDQRLLVKV
Rv2048c|M.tuberculosis_H37Rv        G------------------------DRVMGLFPEGTGTVASTDQRLLVKV
MUL_2266|M.ulcerans_Agy99           G------------------------DRVVGLFPEGTGTIAITDHRLLVKI
MLBr_00135|M.leprae_Br4923          G------------------------DAVMG-FLGGAGPLAVVHQQLITQM
MMAR_3798|M.marinum_M               GRLSTSAHRWLAGHQLGDTVVLPATALIDMALYAGEHTGCPTIDELVLQT
Mflv_0405|M.gilvum_PYR-GCK          G------------------------QRVYGSMQGAFASRFNVPGQFLAPI
MAB_0939|M.abscessus_ATCC_1997      G------------------------QRVYGSMQGAFGSRFNVPAQFLAPI
Mvan_0269|M.vanbaalenii_PYR-1       G------------------------QRVYGFMQGAFASRFNVPAQLLAPI
MSMEG_0408|M.smegmatis_MC2_155      G------------------------QRVYGSMQGAFASRFNVPAQFLAPI
MAV_1763|M.avium_104                G------------------------TRVYGFMQGAFASRFNVPVQLLAPI
TH_4621|M.thermoresistible__bu      G-----------------------DRVGGLSPNGCWSTFVTCDADLAVPL
                                    *                                    .       :    

Mb2074c|M.bovis_AF2122/97           PAGWSHTAAATTSVVFATAHYALVDLADVQPGQRVLIHAGTGGVGMAAVQ
Rv2048c|M.tuberculosis_H37Rv        PAGWSHTAAATTSVVFATAHYALVDLAAARSGQRVLIHAGTGGVGMAAVQ
MUL_2266|M.ulcerans_Agy99           PAGWSDTAAATTSVVFATAFYALRDLASVQPGQRILVHAATGGVGMAAVQ
MLBr_00135|M.leprae_Br4923          PQGWSLAEAAAVPVVFLTALFGLADLAGIRAGESVLIHAGTGGVGMAAVQ
MMAR_3798|M.marinum_M               PLTLTPDAATDLQISVAAPDEQNRRTFSVHARTSEHPHQHSTWVLHASGT
Mflv_0405|M.gilvum_PYR-GCK          PDGVSAVEAATIPAAALTVR-LSFDWAQVKSGDKVLIHAASGGVGLAAVQ
MAB_0939|M.abscessus_ATCC_1997      PDGISGVEAATIPAAALTVR-LSFDWAQLKPGDKVLIHAASGGVGLAAIQ
Mvan_0269|M.vanbaalenii_PYR-1       PDGIGAVDAATIPAAALTAR-LAFDWAQLKPGDRVLIHAASGGVGLAAIQ
MSMEG_0408|M.smegmatis_MC2_155      PDGIGAVEAATIPAAALTVR-LAFDWAQLKPGDKVLIHAASGGVGLAAIQ
MAV_1763|M.avium_104                PDGVSAVDAATIPAAALTAR-LAFDWAQLKPGDRVLIHAASGGVGLAAIQ
TH_4621|M.thermoresistible__bu      PDGLTEGQAAAVSTAHATAWYGLHDLARLGAGEKVLIHSATGGVGLAAIA
                                    *       *:       :            .      *  :  *  *:  

Mb2074c|M.bovis_AF2122/97           LARHLG-----------------------LEVFATASK-GKWDTLRAMGF
Rv2048c|M.tuberculosis_H37Rv        LARHLG-----------------------LEVFATASK-GKWDTLRAMGF
MUL_2266|M.ulcerans_Agy99           LARHWG-----------------------LEVFATASK-GKWDTLRAMGF
MLBr_00135|M.leprae_Br4923          FARHWG-----------------------VEIFVTASR-GKWDTLRDMGF
MMAR_3798|M.marinum_M               LSNHPSRMFSPTTPFAAGRTPNAVDQDSFYEELAQHGV-RYDGAFRALHS
Mflv_0405|M.gilvum_PYR-GCK          MAQQCG-----------------------AEVYATAST-FKRATLRKLGV
MAB_0939|M.abscessus_ATCC_1997      MAQQFG-----------------------AEVFATAST-FKRATLRKLGV
Mvan_0269|M.vanbaalenii_PYR-1       MAQQHG-----------------------AVVFATAST-YKRATLRKLGV
MSMEG_0408|M.smegmatis_MC2_155      MAQQSG-----------------------AEVFATAST-FKRSTLRRLGV
MAV_1763|M.avium_104                LAQRHG-----------------------ATVFATAST-YKRATLRKLGV
TH_4621|M.thermoresistible__bu      IARSVG-----------------------AQIYATAGSPARRDLLRDMGI
                                    ::.  .                           .  .       :* :  

Mb2074c|M.bovis_AF2122/97           DDDHISDSRSLEFEDKFRAATGGRG-------FDVVLDSLAGEFVDAS--
Rv2048c|M.tuberculosis_H37Rv        DDDHISDSRSLEFEDKFRAATGGRG-------FDVVLDSLAGEFVDAS--
MUL_2266|M.ulcerans_Agy99           DEDHIGDSRSLEFEDKFRAATGGRG-------MDVVLDSLAGEFVDAS--
MLBr_00135|M.leprae_Br4923          DDDHIGDSRTLEFEEKFLAVTDGRG-------VDVVLDSLAGDFVDAS--
MMAR_3798|M.marinum_M               LENNPSDTDTTCAEVALPADTDVDGYGIHPALLDAALQPLAAAFTDTDTD
Mflv_0405|M.gilvum_PYR-GCK          K--HVYDSRTTDFAEQILADTDGAG-------VDVVLNSLTSEGFIEAT-
MAB_0939|M.abscessus_ATCC_1997      K--YVYDSRTTDFADQILADTDGAG-------VDVVLNSLTSEGFIEAT-
Mvan_0269|M.vanbaalenii_PYR-1       D--HVYDSRTTEFADQILADTDGEG-------VDVVLNSLTNEGFIEAT-
MSMEG_0408|M.smegmatis_MC2_155      K--YVYDSRTTDFADQILADTNGAG-------VDVVLNSLTSAGFVEAT-
MAV_1763|M.avium_104                E--YVYDSRSTDFADQILADTDGAG-------VDVVLNSLTNEGFIEAT-
TH_4621|M.thermoresistible__bu      E--HVYDSRSTAFADEIRRDTDGYG-------VDVVLNSLPGAAQRAG--
                                          *: :      :   *.  *       .*..*:.*.         

Mb2074c|M.bovis_AF2122/97           ---------------------------LRLVAPGGVFLEMGKTDIRDPGV
Rv2048c|M.tuberculosis_H37Rv        ---------------------------LRLVAPGGVFLEMGKTDIRDPGV
MUL_2266|M.ulcerans_Agy99           ---------------------------LRLVAPGGVFLEMGKTDIREAAV
MLBr_00135|M.leprae_Br4923          ---------------------------LRLLVRGGRFLEMGKTDIRDAQE
MMAR_3798|M.marinum_M               APSAATPRMPFVITGVNLHATGARRLLVQLTATDADTFSLHATDPAGATV
Mflv_0405|M.gilvum_PYR-GCK          ---------------------------LRATAQHGRFAEIAKRDIWTVEQ
MAB_0939|M.abscessus_ATCC_1997      ---------------------------LRATAKNGRFAEIAKRDIWTTEQ
Mvan_0269|M.vanbaalenii_PYR-1       ---------------------------VRATAQNGRFAEIAKRDIWTPEQ
MSMEG_0408|M.smegmatis_MC2_155      ---------------------------LKATAQGGRFAEIAKRDIWSHEQ
MAV_1763|M.avium_104                ---------------------------VRATAQHGRFVEIAKRDIWTREQ
TH_4621|M.thermoresistible__bu      ---------------------------LELLSFGGRFIEIGKRDIYGDTR
                                                               :.     .   .:   *      

Mb2074c|M.bovis_AF2122/97           IAQQ--YPGVR-------YRAFDLFEAGPDRIAQILAELATLFGDG----
Rv2048c|M.tuberculosis_H37Rv        IAQQ--YPGVR-------YRAFDLFEPGPDRIAQILAELATLFGDG----
MUL_2266|M.ulcerans_Agy99           VAQQ--HTGVR-------YRAFDLFEAGPDHIAQILAELAALFSED----
MLBr_00135|M.leprae_Br4923          IAAN--YPGVQ-------YRAFDLSEAGPVRMQEMLCEVRELFDTQ----
MMAR_3798|M.marinum_M               ITIN--AVTLRALTDIGSLRTSGISRRGLLELAWPALPPDTFSTAA----
Mflv_0405|M.gilvum_PYR-GCK          MAAA--RPDLAY----EIVALDTVMFTEPDRIRDLLTEVSAGLRDG----
MAB_0939|M.abscessus_ATCC_1997      MAQS--RPDIAY----EIVALDTVMFQEPDRIRVLLTEVSEGLAKG----
Mvan_0269|M.vanbaalenii_PYR-1       MAAA--RPDIAY----EIVALDTVTLLEPERIRGLLGEVSDGLGKADGSS
MSMEG_0408|M.smegmatis_MC2_155      MAEA--RPDIAY----EIVALDTVMFTEPDRIRDLLTEVSDGMARG----
MAV_1763|M.avium_104                MAAA--RPDIAY----EIVALDWACVEQPEHIHALLTEVSDGLASG----
TH_4621|M.thermoresistible__bu      LGLFPFRRNLAFHG----VDLGLMADSHPHKIRELLETVYRLTADG----
                                    :        :                    .:                  

Mb2074c|M.bovis_AF2122/97           --VLRPLPVTT---------------------------------FDVRRA
Rv2048c|M.tuberculosis_H37Rv        --VLRPLPVTT---------------------------------FDVRCA
MUL_2266|M.ulcerans_Agy99           --VLRPLPVTT---------------------------------FDVRRA
MLBr_00135|M.leprae_Br4923          --VLHRLPVTS---------------------------------WDVRCA
MMAR_3798|M.marinum_M               --VLPPLALVSSHSDDLAHALGQSSQCTVYTDLAAVQPCPPLVLWDLTAG
Mflv_0405|M.gilvum_PYR-GCK          --AWTPLPAEV-------------------------YPLTEAR-------
MAB_0939|M.abscessus_ATCC_1997      --EWTPLPAEI-------------------------YPLTEAR-------
Mvan_0269|M.vanbaalenii_PYR-1       RAEWVPLPAEI-------------------------YPLTEAR-------
MSMEG_0408|M.smegmatis_MC2_155      --EWTPLPAEI-------------------------YPITEAR-------
MAV_1763|M.avium_104                --EWRPLPAEI-------------------------YPLAEAK-------
TH_4621|M.thermoresistible__bu      ---VLPMPQSTHYP------------------------------------
                                          :.                                          

Mb2074c|M.bovis_AF2122/97           P-------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        P-------------------------------------------------
MUL_2266|M.ulcerans_Agy99           P-------------------------------------------------
MLBr_00135|M.leprae_Br4923          P-------------------------------------------------
MMAR_3798|M.marinum_M               PDPTPTPEDGDTEDPLQRVHTLTRHTLAGLQNWLNRSDTTGTHLVILTRR
Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
Mvan_0269|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
MAV_1763|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           ------------------AALRYLSQARHTGKVVMLMP------------
Rv2048c|M.tuberculosis_H37Rv        ------------------AALRYLSQARHTGKVVMLMP------------
MUL_2266|M.ulcerans_Agy99           ------------------AALRYLSQARHVGKVVLTMP------------
MLBr_00135|M.leprae_Br4923          ------------------AAFRFMSQARHIGKVVLTMPS-----------
MMAR_3798|M.marinum_M               AVTTVPDDRSPDPAHAATWAFAHSAQNEHPNRITLIDIDNTPATSQTLTN
Mflv_0405|M.gilvum_PYR-GCK          ------------------AAFRRMQQARHIGKIVVQIPN-----------
MAB_0939|M.abscessus_ATCC_1997      ------------------TAFRRMQQARHIGKIVCQMPN-----------
Mvan_0269|M.vanbaalenii_PYR-1       ------------------AAFRRMQQARHVGKIVLQMPK-----------
MSMEG_0408|M.smegmatis_MC2_155      ------------------SAFRRMQQARHIGKIVLQVPK-----------
MAV_1763|M.avium_104                ------------------TAFRRMQQARHIGKIVLQMPK-----------
TH_4621|M.thermoresistible__bu      -------------LAEAATAIRVMSAAEHVGKLVLDVPHTG---------
                                                       *:      .* .::.                

Mb2074c|M.bovis_AF2122/97           -------------------------------------------GSWAAGT
Rv2048c|M.tuberculosis_H37Rv        -------------------------------------------GSWAAGT
MUL_2266|M.ulcerans_Agy99           -------------------------------------------DAWAAGT
MLBr_00135|M.leprae_Br4923          ----------------------------------------ALADGLAEGT
MMAR_3798|M.marinum_M               ILTTLTNPTSAPTEPQLALRHGTPHTPRLTPTTTETTTTSPPLEFDPAGT
Mflv_0405|M.gilvum_PYR-GCK          -----------------------------------------PLQPQPDRS
MAB_0939|M.abscessus_ATCC_1997      -----------------------------------------PLAPRPDRT
Mvan_0269|M.vanbaalenii_PYR-1       -----------------------------------------PLQPRADRS
MSMEG_0408|M.smegmatis_MC2_155      -----------------------------------------PLQPQQDRS
MAV_1763|M.avium_104                -----------------------------------------PLQPRGDRS
TH_4621|M.thermoresistible__bu      -------------------------------RADVVVPPEQASPFRSDGA
                                                                                     :

Mb2074c|M.bovis_AF2122/97           VLITGGTGMAGSAVARHVVARHGVRNLVLVSRRGPDAPGAAELVAELAAA
Rv2048c|M.tuberculosis_H37Rv        VLITGGTGMAGSAVARHVVARHGVRNLVLVSRRGPDAPGAAELVAELAAA
MUL_2266|M.ulcerans_Agy99           VLITGGTGMAGSALARHVVAHHGVRQLVLVSRRGPDAPGAAELAEELSAF
MLBr_00135|M.leprae_Br4923          VLITGASGAIGGVLARHMVSAYGVRHLVLASRRGDRAEGAVELAAELVGA
MMAR_3798|M.marinum_M               VLITGGTGMLGAVFAEHMIARYGARHLLLVSRSGPDAPGADDLYQRLTQL
Mflv_0405|M.gilvum_PYR-GCK          YLITGGLGAIG-LHTAGYLAQLGAGDIVLTSRRAPDAAAQQAIADIADRT
MAB_0939|M.abscessus_ATCC_1997      YLITGGLGAIG-LHTAAYLAQLGAGDIVLTSRRAPDTDAQRVIGEITERS
Mvan_0269|M.vanbaalenii_PYR-1       YLITGGLGAIG-LHTAAYLAQLGAGDLVLTSRRAPDADARRAIEEITERY
MSMEG_0408|M.smegmatis_MC2_155      YLITGGLGAIG-LHTAAYLAQLGAGDIVLTSRRDPDESAQRAIDEITERH
MAV_1763|M.avium_104                YLITGGLGAIG-LHLAAYLAQLGAGEIVLTSRRAPDAAAWRAIDDITERY
TH_4621|M.thermoresistible__bu      YIVTGGMGGLG-LYLAGEMAAAGAGCIVLNGRSAPSGEALRTIEQLRAAG
                                     ::**. *  *       ::  *.  ::* .*      .   :       

Mb2074c|M.bovis_AF2122/97           GAQVQVVACDAADRAALAKVIADIPVQHP-LSGVIHTAGALDDAVVMSLT
Rv2048c|M.tuberculosis_H37Rv        GAQVQVVACDAADRAALAKVIADIPVQHP-LSGVIHTAGALDDAVVMSLT
MUL_2266|M.ulcerans_Agy99           GAQVQVVACDAADRAALAKLIADIPMQHP-LSAVIHTAGALDDAVVTSLT
MLBr_00135|M.leprae_Br4923          GAKIQVVACDVADNDAVRGLFAQLSREFPPVRGVIHAAGVLDDGAITSLT
MMAR_3798|M.marinum_M               GAQITITACDASDPTALAAVLANIPTEHP-LRAVIHTAAVIDDAVVTELT
Mflv_0405|M.gilvum_PYR-GCK          KARLHVFTADVGVEADVAALLERIRAELPPLAGVAHLAGVLDDALLSQQS
MAB_0939|M.abscessus_ATCC_1997      KTRIHVFTADVGAESEVAGLLERIRAELPPLAGVAHLAGVLDDALLGQQS
Mvan_0269|M.vanbaalenii_PYR-1       KCRVHTFCADVGDESQVAELLARIRAELPPLAGVAHLAGVLDDALLSQQS
MSMEG_0408|M.smegmatis_MC2_155      KCRIHTYAADVGDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQN
MAV_1763|M.avium_104                RCRVHTFAADVGDAAQVEQLLARIRAELPPLAGVAHLAGVLDDALLSQQS
TH_4621|M.thermoresistible__bu      TEVIVECGXXX---------------RGQPVEVAVPTELRHADEHPDRRG
                                       :                      .   :           *       

Mb2074c|M.bovis_AF2122/97           PDRVDVVLRSKVDAAWHLHELTRDLDVSAFVMFSSMAGLVGSSGQANYAA
Rv2048c|M.tuberculosis_H37Rv        PDRVDVVLRSKVDAAWHLHELTRDLDVSAFVMFSSMAGLVGSSGQANYAA
MUL_2266|M.ulcerans_Agy99           PERIETVLRAKVDAAWNLHELTRDMDLSAFVMFSSMAGLVGSSGQGNYAA
MLBr_00135|M.leprae_Br4923          PDRVDTVLRAKVDAAWNLHEATRDLDLLMFVLCSSIAATVGSPGQGNYSA
MMAR_3798|M.marinum_M               VEQLDMVLAAKADTAWHLHRLTADINLDVFVVFSAAAAVLGAPGLANYAA
Mflv_0405|M.gilvum_PYR-GCK          VERFRTALAPKAFGAVHLDRLTRVDDLDFFLVSSSVSSLFGSPGQSNYAT
MAB_0939|M.abscessus_ATCC_1997      VERFRTTLAPKAFGAEYLDRLTKGDDLDFFIVSSSVSSLFGSPGQSNYAT
Mvan_0269|M.vanbaalenii_PYR-1       LERFRTTLAPKAFGACHLDRLTAGDDLDFFIMSSSVSSLFGSPGQANYAT
MSMEG_0408|M.smegmatis_MC2_155      PERFRTTLAPKAYGASHLDRLTRDDDLDFFIVSSSVSSLFGSPGQANYAT
MAV_1763|M.avium_104                PERFRVALAPKAFGASYLDHATRTDDLDFFIVSSSVSSLLGSPGQANYST
TH_4621|M.thermoresistible__bu      AQLCDEFARGEQGAQRNQHRTDAGEGQRDAHPPGAVGHDQPDPGALSDTG
                                     :        :       ..     .       .: .     .*  . : 

Mb2074c|M.bovis_AF2122/97           ANSFLDALAAHRRAHGLPAISLGWGLWDQASAMTSGLATVDFKRFARDGI
Rv2048c|M.tuberculosis_H37Rv        ANSFLDALAAHRRAHGLPAISLGWGLWDQASAMTGGLATVDFKRFARDGI
MUL_2266|M.ulcerans_Agy99           ANSFLDGLAVHRQAHGLPAISLGWGLWDQASNMTGGLAAVDFKRFARDGI
MLBr_00135|M.leprae_Br4923          ANAFLDGLAAYRQAAGLAGTSLAWGLWEQPGGMNAHLSSRDLARISRSGL
MMAR_3798|M.marinum_M               ANAFLDALAHHRHHHGLPATSLAWGYWQTPG-IAAHLDTVSQARFTRNHL
Mflv_0405|M.gilvum_PYR-GCK          ANAFLDGLVAQRRAQGLPATGVNFGPWARGGMASSEAAAANIS---AQGL
MAB_0939|M.abscessus_ATCC_1997      ANALLDGLIAQRRAQGLPATGINFGPWGQGGMASSEAATANIS---AQGL
Mvan_0269|M.vanbaalenii_PYR-1       ANALLDGLTAHRRARGLPATGVNFGPWAQGGMASSEAATANIG---AQGL
MSMEG_0408|M.smegmatis_MC2_155      ANAMLDGLVAKRRAQGLVATGINFGPWGQGGMASSEAATANIT---AQGL
MAV_1763|M.avium_104                ANAWLDGLVAARQARGLPATGVNLGPWAQGGMASSEAARANIG---AQGL
TH_4621|M.thermoresistible__bu      LDERGGQFPGVGVQIPVADPGVGIDHRGAVRVDSGVPAQQGVDG------
                                     :   . :        :   .:  .         .     .         

Mb2074c|M.bovis_AF2122/97           VAMSSADALQLFDTAMIVDEPFMLPAHIDFAALKVKFDGGTLPPMFVDLI
Rv2048c|M.tuberculosis_H37Rv        VAMSSADALQLFDTAMIVDEPFMLPAHIDFAALKVKFDGGTLPPMFVDLI
MUL_2266|M.ulcerans_Agy99           VAMSSDEALGLLDTAMVLGEPFMLPAHIDFAALRVKFDGGTLPPMFVDLI
MLBr_00135|M.leprae_Br4923          APMNPAQALELFDAALVIDHPFMVTALLDRAALDAQAQAGALPPLFSRLV
MMAR_3798|M.marinum_M               IPITTEHGLALFDAALACQQPNLVPAPLNTHTLARQARQGVLPAILSSLI
Mflv_0405|M.gilvum_PYR-GCK          IPLEPSAALTAMAEVVANGTAQATVLKANWQRAAKVLGSSRPPILDLVLP
MAB_0939|M.abscessus_ATCC_1997      IPLDPSAALAALAEVVANGTGQATILKANWQRAAKVLGSSRPPILDLVLP
Mvan_0269|M.vanbaalenii_PYR-1       VPLEPSAALGALAEVLANGTGQAAVLKANWQRAAKVLGSSRPPILDLVLP
MSMEG_0408|M.smegmatis_MC2_155      IPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSARPPILDLVLP
MAV_1763|M.avium_104                IPLEPTAALAALAEVVANGTGQATVIKANWQRAAKLLGGARPPILDLVLP
TH_4621|M.thermoresistible__bu      -----EVVRHRTLSSVRSGRSSRWTAPGSRCGSGRRYGGESCRRTTGPAA
                                                   :            .                     

Mb2074c|M.bovis_AF2122/97           NAPTRRQVDDSLAAAKSKSALAHRLHGLPEDEQHAVLLDLVRSHIATVLG
Rv2048c|M.tuberculosis_H37Rv        NAPTRRQVDDSLAAAKSKSALLQRLEGLPEDEQHAVLLDLVRSHIATVLG
MUL_2266|M.ulcerans_Agy99           NAPTRRQVDDSLAAAKSKSALLQRLEGLPEDEQHAILLNLVRSHIATVLG
MLBr_00135|M.leprae_Br4923          RRSRRRQIEDPGDATQSKLALVQRLQGLAANRQLELLVGVVCLQAAAVLG
MMAR_3798|M.marinum_M               TTRRHATIG-------SVETLTAQLATQTPEQQLATLTRLVTTATAAVLA
Mflv_0405|M.gilvum_PYR-GCK          SAVGE---------ITGDSELLKQLQEIPVPQRAGFVTEFLQKEVQNFLR
MAB_0939|M.abscessus_ATCC_1997      SAVGE---------VTGDSELLKQLMEIPVPQRAGFVTEFLQREVQNFLR
Mvan_0269|M.vanbaalenii_PYR-1       RPEGE---------VAGDSELLRQLQEIPVAQRAGFVTEFLQREVQNFLR
MSMEG_0408|M.smegmatis_MC2_155      SAAGE---------ATGDSELLKQLMEIPIPQRAGFVTEFLQREVQNFLR
MAV_1763|M.avium_104                SAVGE---------ASGDSELLKQLQEIPVAQRAAFITEFLQREVQGFLR
TH_4621|M.thermoresistible__bu      GAAAR----------------RGRTRRRRRPRRPPPPPDRVRHRAGPAHG
                                        .                  :       .:       :         

Mb2074c|M.bovis_AF2122/97           SASPEAIDPDRAFQDLGFDSLTAVEMRNRLKSATG--LSLSPTLIFDYPN
Rv2048c|M.tuberculosis_H37Rv        SASPEAIDPDRAFQELGFDSLTAVEMRNRLKSATG--LALSPTLIFDYPN
MUL_2266|M.ulcerans_Agy99           NSSPDAIDPDRAFQELGFDSLTAVEMRNRLKSATG--LALSPTLIFDYPN
MLBr_00135|M.leprae_Br4923          RPSPEDIDPNTKFQDLGFDSLTAVELRNRLKSATG--LTLPPTVIFDHPT
MMAR_3798|M.marinum_M               HPDPATLEPDLPFKDLGIDSLSALELRNTLTRDTG--ASLPATLVFDHPT
Mflv_0405|M.gilvum_PYR-GCK          LAQPPAATSR--FLDLGTDSLMAIELRNRLHSQFGGAFTINATAVFDYPT
MAB_0939|M.abscessus_ATCC_1997      LAQPPAATSR--FLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPT
Mvan_0269|M.vanbaalenii_PYR-1       LAQPPAATSR--FLDLGTDSLMAIELRNRLHSQFGGAFTINATAVFDYPT
MSMEG_0408|M.smegmatis_MC2_155      LASPPAASSR--FLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPT
MAV_1763|M.avium_104                LAQPPAATSR--FLDLGTDSLMAVELRNRLHSQFGGAFTINATAVFDYPT
TH_4621|M.thermoresistible__bu      PVRR----------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           SAALAGYMRRELLGSSPQ-DTSAVAAGEAELQRIVASIPVKRLRQAGVLD
Rv2048c|M.tuberculosis_H37Rv        SAALAGYMRRELLGSSPQ-DTSAVAAGEAELQRIVASIPVKRLRQAGVLD
MUL_2266|M.ulcerans_Agy99           SAALAGYMHRELVGASPQSDTTAEAPGEAELQRVVASIPVKRLRQAGVLE
MLBr_00135|M.leprae_Br4923          PTAVAEYVAQQMLKSRPA------ESGDETSQAVEPKVEEVSVHA-----
MMAR_3798|M.marinum_M               PSAIAQYLNIQLSGSSTT--SRVQDPEEIEMQNLIAKIPAKQLIKSGVLN
Mflv_0405|M.gilvum_PYR-GCK          IGGLAEYLVAQLPDAETPQAAP-------QSESEPGPDVTE---------
MAB_0939|M.abscessus_ATCC_1997      IGGLAEYLVGQLPDADAESAEAPPAVESAEAESGAGPAAASDAVSELKE-
Mvan_0269|M.vanbaalenii_PYR-1       IGGLAEYLVGQLPDSDAAAGETPATETSPIDHNHPDREADSPG-------
MSMEG_0408|M.smegmatis_MC2_155      IGGLAEYLVGQLPDAEAPETA-----------------------------
MAV_1763|M.avium_104                IGGLAEYLAGQLPDAESEPGAAVAANPNPGSETGTGEAEPEREAAPEPS-
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           LLLALANETETSGQDPALAPTAEQEIADMDLDDLVNAAFRNDDE
Rv2048c|M.tuberculosis_H37Rv        LLLALANETETSGQDPALAPTAEQEIADMDLDDLVNAAFRNDDE
MUL_2266|M.ulcerans_Agy99           LLLALANETGGNGQAAVTAETSEEDLADMDLDALVNAAFMNDDE
MLBr_00135|M.leprae_Br4923          --------------------------------------------
MMAR_3798|M.marinum_M               ILREIADIEHSSSANEKQDNVATMNLDELLIALGDHKGENKNDH
Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------
Mvan_0269|M.vanbaalenii_PYR-1       --------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------
MAV_1763|M.avium_104                --------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------