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MTASVEGADQKSEKLISYLKKVVVELDETRARLREYEQRATEPVAVVGIGCRFPGGVDSPDRLWDVVSEC RDVVSEFPTDRGWDVDGLFDPDPDAEGKTYTRWGAFLDDAAGFDAGFFGIAPSEVLAMDPQQRLMLEVSW EALEYAGIDPLSLRGSATGVFTGIFAPSYGSRDTGGLQGYGLTGTAVSVASGRVSYVLGLEGPAVSVDTA CSSSLVAIHWAMSSLRSGECDLALAGGVTVMGLPSIFVGFSRQRGLAADGRCKAFARAADGTGWGEGAGV VVLERLSDAQRLGHTVLAVVRGSAVNQDGASNGLTAPNGLAQQRVIQAALTNAGLSSADVDVVEAHGTAT TLGDPIEAQALLATYGQGRPADQPLWVGSIKSNMGHTQAAAGVAGVIKMVQAMRHHVMPATLHVDEPSPR VDWTTGAVSVLTEARDWSVEGRPRRAGVSSFGISGTNAHVILEEAPTPVEASYSTADQQRLSVVPWVVSG RSTAALMAQASRLAFYVQADPEVDPVDVGCALAARSVFEHRAVVVGESREQLIAGLAGLAVGESGAGVAI GQAAPLGKTVVVFPGQGAQRIGMGRELCSQLPVFAEEFDAVTGELDRHMRLPLRDVVWGADAGLLDSTEF AQPALFAVEVALFAVLQHWGLQPDFVMGHSIGELAAAYVAGVLAPADAAMLVVARGRLMQSMPAGGTMWA VAASEDEVVSLLGEGVGIAAINAPESVVISGPQAAVSAIADKFAAQGRRVHQLAVSHAFHSPLMEPMLEE FVRVAAQVEVRKPQIGLVSNVTGELAGPDFGSPQYWGEHVSRAVRFVDSARHLQTLGATHFIESGPSSGL MGAIEQSLAPAEAVVVSMMGKDRPELASVLGAAGQLFATGMPVEWPAVFAGSSRRRVTLPTYAFQRRRFW ETPGTDGTASVSGLGLGSTEHALLGAVVERPDSGGVVLTGRLSLANQPWLADHVIGGVVLFPGAGFVELV IRAGDEVGCAGVEELVLAAPLVLHPGSGVQVQVVVAAADESSRRAVSVYSRGDQSHGGWLLNAEGLLEVD AAEATVDLSLWPPEGAESVDISDAYPQLAERGYAYGPAFQGLVAIWRRGSELFAEVVAPTGVVVDGMGMH PALLDAVLHALGLAIENTQATTEMRLPFCWRGVSLHAGGAGRVRARFTSAGADAIAVDIADSAGLPVLTV RSLVTRAMTAEQLRTAVTAAGGALEQGPMDLVWSPIPLSSDGHGGGLPSVVSWADYCAGRGNDTGVVVWE FGSASAGAQAPVDSVAAVYSATHAALQVLQFWFGQDRAGTLVVLTRGAVGLVGEGISDLAAAAVWGMVRS AQSEHSGKIVLIDTDSAVDVAVLADLGESQLLVRCNTVHAARLSPAPQLLALPVGESMWRLAADGGGTLE DLVIQPCPEVQAPLQAGHMRVAVAAVGVNFRDVVAALGMYPGQAPPLGAEGAGVVIEIGPEVTGVAVGDA VMGFLGGAGPLAVVHQQLITQMPQGWSLAEAAAVPVVFLTALFGLADLAGIRAGESVLIHAGTGGVGMAA VQFARHWGVEIFVTASRGKWDTLRDMGFDDDHIGDSRTLEFEEKFLAVTDGRGVDVVLDSLAGDFVDASL RLLVRGGRFLEMGKTDIRDAQEIAANYPGVQYRAFDLSEAGPVRMQEMLCEVRELFDTQVLHRLPVTSWD VRCAPAAFRFMSQARHIGKVVLTMPSALADGLAEGTVLITGASGAIGGVLARHMVSAYGVRHLVLASRRG DRAEGAVELAAELVGAGAKIQVVACDVADNDAVRGLFAQLSREFPPVRGVIHAAGVLDDGAITSLTPDRV DTVLRAKVDAAWNLHEATRDLDLLMFVLCSSIAATVGSPGQGNYSAANAFLDGLAAYRQAAGLAGTSLAW GLWEQPGGMNAHLSSRDLARISRSGLAPMNPAQALELFDAALVIDHPFMVTALLDRAALDAQAQAGALPP LFSRLVRRSRRRQIEDPGDATQSKLALVQRLQGLAANRQLELLVGVVCLQAAAVLGRPSPEDIDPNTKFQ DLGFDSLTAVELRNRLKSATGLTLPPTVIFDHPTPTAVAEYVAQQMLKSRPAESGDETSQAVEPKVEEVS VHA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. leprae Br4923 | MLBr_00135 | - | - | 100% (2103) | putative polyketide synthase |
| M. leprae Br4923 | MLBr_02355 | - | 0.0 | 31.70% (2230) | polyketide synthase |
| M. leprae Br4923 | MLBr_00139 | mas | 0.0 | 32.89% (2159) | putative mycocerosic synthase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2971c | pks1 | 0.0 | 84.46% (2111) | polyketide synthase PKS1 |
| M. gilvum PYR-GCK | Mflv_0405 | - | 0.0 | 37.91% (2163) | beta-ketoacyl synthase |
| M. tuberculosis H37Rv | Rv2946c | pks1 | 0.0 | 82.53% (1620) | polyketide synthase PKS1 |
| M. abscessus ATCC 19977 | MAB_0939 | - | 0.0 | 38.63% (2164) | polyketide synthase |
| M. marinum M | MMAR_1762 | pks15/1 | 0.0 | 79.22% (2113) | polyketide synthase Pks15/1 |
| M. avium 104 | MAV_3108 | - | 0.0 | 60.49% (2088) | erythronolide synthase, modules 3 and 4 |
| M. smegmatis MC2 155 | MSMEG_0408 | - | 0.0 | 38.43% (2147) | type I modular polyketide synthase |
| M. thermoresistible (build 8) | TH_4621 | - | 0.0 | 34.74% (1845) | PUTATIVE mycocerosic acid synthase |
| M. ulcerans Agy99 | MUL_2005 | pks15/1 | 0.0 | 78.75% (2113) | polyketide synthase Pks15/1 |
| M. vanbaalenii PYR-1 | Mvan_1003 | - | 0.0 | 38.57% (2175) | beta-ketoacyl synthase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0405|M.gilvum_PYR-GCK --------------MGSAAHQGE-SAHRFAIVGYAGRFPGARDAESFWEL
MAB_0939|M.abscessus_ATCC_1997 --------------MDSAENPIE-STPRFAIIGYAARFPGAADAEEFWDV
MSMEG_0408|M.smegmatis_MC2_155 --------------MVSAEHPIE-PTPSFAIIGYAARFPGAASAEEYWAL
Mvan_1003|M.vanbaalenii_PYR-1 MTDLQKRALQAIEVLRARVRELEGAGDGYAIVGYALRFPGAADADEFWDV
Mb2971c|M.bovis_AF2122/97 --------------------------------------------------
Rv2946c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MMAR_1762|M.marinum_M --------------------------------------------------
MUL_2005|M.ulcerans_Agy99 --------------------------------------------------
MAV_3108|M.avium_104 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK LADGRDAISEVPEDRWDVEAFFDPDPSTPGKVVTRRAGFVDDVSGFDAPF
MAB_0939|M.abscessus_ATCC_1997 LREGRDAISEVPADRWDAEEFFDPEPGAPGKVVTRRAGFVEDVTGFDAPF
MSMEG_0408|M.smegmatis_MC2_155 LRDGREAISDVPKDRWDIEEFFDPDPSTPGKVVTRRAGFVDDVTGFDAPF
Mvan_1003|M.vanbaalenii_PYR-1 LRGGRDAISEVPQDRWDADEFFDADPEAAGKMVTRRAGFVEDVAGFDAPF
Mb2971c|M.bovis_AF2122/97 --------------------------------------------------
Rv2946c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MMAR_1762|M.marinum_M --------------------------------------------------
MUL_2005|M.ulcerans_Agy99 --------------------------------------------------
MAV_3108|M.avium_104 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK FGMSTREVRLMDPQHRLLLETAWRAIEHSGTAPSELANTNTGVFVGLATH
MAB_0939|M.abscessus_ATCC_1997 FGMSTREVRLMDPQHRLLLETAWRAVEHSGIAPTDLAETNSGVFVGLATH
MSMEG_0408|M.smegmatis_MC2_155 FGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNTGVFVGLATH
Mvan_1003|M.vanbaalenii_PYR-1 FGVSAREAMFMDPQHRLLLETAWRAVEHSGTAPSALAGTRTGVFMGLSTH
Mb2971c|M.bovis_AF2122/97 --------------------------------------------------
Rv2946c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MMAR_1762|M.marinum_M --------------------------------------------------
MUL_2005|M.ulcerans_Agy99 --------------------------------------------------
MAV_3108|M.avium_104 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK DYLGMASDELSYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACS
MAB_0939|M.abscessus_ATCC_1997 DYLGMASDELTFPEIEAYMAIGTSNAAAAGRISYRLGLQGPSVAVDTACS
MSMEG_0408|M.smegmatis_MC2_155 DYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACS
Mvan_1003|M.vanbaalenii_PYR-1 DYLGMLTDNLTHDAIEAYLGTGTSPAAAIGRISYRLGLQGPAVAVDTACS
Mb2971c|M.bovis_AF2122/97 --------------------------------------------------
Rv2946c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MMAR_1762|M.marinum_M --------------------------------------------------
MUL_2005|M.ulcerans_Agy99 --------------------------------------------------
MAV_3108|M.avium_104 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK SSLVAIHQACQALRLGECDLALAGGANVILTPATMITFSNAHMLAPDGRC
MAB_0939|M.abscessus_ATCC_1997 SSLVAIHQACQALQLGECDLALAGGANVLLTPATMITFSHAHMLAPDGKC
MSMEG_0408|M.smegmatis_MC2_155 SSLVAIHQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRC
Mvan_1003|M.vanbaalenii_PYR-1 SSLVAVHQACQALRLAECDVALAGGVNVLLSPATMINFSRARMLAPDGRC
Mb2971c|M.bovis_AF2122/97 --------------------------------------------------
Rv2946c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MMAR_1762|M.marinum_M --------------------------------------------------
MUL_2005|M.ulcerans_Agy99 --------------------------------------------------
MAV_3108|M.avium_104 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK KTFDAAADGYVRGEGCGVIVIKRLEDAVRDGDRIRAVIRGSAINQDGASG
MAB_0939|M.abscessus_ATCC_1997 KTFDAAADGYVRGEGSGVIVIKRLEDAIRDGDRIRAVIRGSAINQDGASG
MSMEG_0408|M.smegmatis_MC2_155 KTFDAAADGYVRGEGCGVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASG
Mvan_1003|M.vanbaalenii_PYR-1 KTFDATADGYVRGEGCGVVVVKRLADAIRHGDRIRAVIRGSAVNQDGASG
Mb2971c|M.bovis_AF2122/97 --------------------------------------------------
Rv2946c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MMAR_1762|M.marinum_M --------------------------------------------------
MUL_2005|M.ulcerans_Agy99 --------------------------------------------------
MAV_3108|M.avium_104 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK GLTVPNGVAQQRVIGDALSRAGLAPGDVDYLEAHGTGTSLGDPIEAQAAG
MAB_0939|M.abscessus_ATCC_1997 GLTVPNGVAQQRVIADALKRAGVAPSEVGYLEAHGTGTSLGDPIEAQAAG
MSMEG_0408|M.smegmatis_MC2_155 GLTVPNGVAQQRVIADALKRAGLRPADVGYLEAHGTGTSLGDPIEAQAAG
Mvan_1003|M.vanbaalenii_PYR-1 GLTVPNGAAQQRVIADALTNAGLTAADVDYLEAHGTGTPLGDPIEVQAAG
Mb2971c|M.bovis_AF2122/97 --------------------------------------------------
Rv2946c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MMAR_1762|M.marinum_M --------------------------------------------------
MUL_2005|M.ulcerans_Agy99 --------------------------------------------------
MAV_3108|M.avium_104 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK AALGPGREPQRPLLIGSAKTNIGHLEAAAGIAGVIKVVLSLEHETLPKHL
MAB_0939|M.abscessus_ATCC_1997 AAYGIGRETNDPLLIGSAKTNIGHLEAAAGIAGVIKVILSLENELLPQHR
MSMEG_0408|M.smegmatis_MC2_155 EVLGAGRAPEEPLLIGSAKTNIGHLEAAAGIAGVIKVVMALENETLPKHL
Mvan_1003|M.vanbaalenii_PYR-1 AVLGVGREPDRPLLIGSVKTNIGHLEAASGIAGLLKVILSLEHQVLPKHL
Mb2971c|M.bovis_AF2122/97 --------------------------------------------------
Rv2946c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MMAR_1762|M.marinum_M --------------------------------------------------
MUL_2005|M.ulcerans_Agy99 --------------------------------------------------
MAV_3108|M.avium_104 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK NFENPSPHIPWDRLPVEVVKESIPWRRGQRGGRPRIAGVSSFGFAGTNAH
MAB_0939|M.abscessus_ATCC_1997 NFQNPSPHIPWDRLPVEVVREARPWGR---NGRPRIAGVSSFGFAGTNAH
MSMEG_0408|M.smegmatis_MC2_155 NFETPSPHIPWERLPIEVVRETVPWQR---NGKPRIAGVSSFGFAGTNAH
Mvan_1003|M.vanbaalenii_PYR-1 NFRSPSPHIPWNRLPVRIVDDPVPWTR---SGRSRVAGISSFGFSGTNAH
Mb2971c|M.bovis_AF2122/97 --------------------------------------------------
Rv2946c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MMAR_1762|M.marinum_M --------------------------------------------------
MUL_2005|M.ulcerans_Agy99 --------------------------------------------------
MAV_3108|M.avium_104 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK VILEEAPLAAEPAQES---VDDGRFTLLPLSARTPAALMAVADRYRDWLV
MAB_0939|M.abscessus_ATCC_1997 VILEEAPVVSRDAVEPPAPAGGRKFSILPLSARTPAALAQLADKYRAWLN
MSMEG_0408|M.smegmatis_MC2_155 VILEEAPAVGTPATTEP-VEDPRRYSVLPLSARTPEALVRLAGEYRDWLR
Mvan_1003|M.vanbaalenii_PYR-1 VLVEEAPRADRAGAAPQ-PAAPGGFGMLPLSARTPDALAATAHRLRTWLA
Mb2971c|M.bovis_AF2122/97 --------------------------------------------------
Rv2946c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MMAR_1762|M.marinum_M --------------------------------------------------
MUL_2005|M.ulcerans_Agy99 --------------------------------------------------
MAV_3108|M.avium_104 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK ANPDATLADLCFTAGTARSHLEHRAALVVNTREAALDLLGALADDRPAPG
MAB_0939|M.abscessus_ATCC_1997 AHPEAALADLCFTAGVGRAHLEHRAALVVNTREAAVELLSAVADDRPAPG
MSMEG_0408|M.smegmatis_MC2_155 AHPQARLADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPG
Mvan_1003|M.vanbaalenii_PYR-1 ANPDASWPDLCFTAAVGRSHLRHRAALVVDSRSSVEELLGALAEDRPGPG
Mb2971c|M.bovis_AF2122/97 --------------------------------------------------
Rv2946c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MMAR_1762|M.marinum_M --------------------------------------------------
MUL_2005|M.ulcerans_Agy99 --------------------------------------------------
MAV_3108|M.avium_104 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK LVRGESHDTPKTAWLFTGQGSQYPGMSRELFDTEPLFAETLRECAAAVDG
MAB_0939|M.abscessus_ATCC_1997 LGRGESHDTPKTAWLFTGQGSQYPGMARELFETEPVFADTLNRCAAAVAD
MSMEG_0408|M.smegmatis_MC2_155 LVRGESHEAPKTAWLFTGQGSQYPGMARELFDTEPVFAETVRKCAEAVAD
Mvan_1003|M.vanbaalenii_PYR-1 LARGECGDPPKTAWLFTGQGSQYPGMGRELFDTEPVYREVMTRCAEAVAD
Mb2971c|M.bovis_AF2122/97 --------------------------------------------------
Rv2946c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MMAR_1762|M.marinum_M --------------------------------------------------
MUL_2005|M.ulcerans_Agy99 --------------------------------------------------
MAV_3108|M.avium_104 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK MLEKPLLDVIFDTDGVLDTDSNETLRHTSYAQPALFAVEMGLARLWQSWG
MAB_0939|M.abscessus_ATCC_1997 VLEKPLLDVIFDVD---GPEAEETLRQTSYAQPALFAVEMGLARLWQSWG
MSMEG_0408|M.smegmatis_MC2_155 ILEKPLLDVIFDAD-ELDGDTESPLRHTTYAQPALFAVELGLARLWQSWG
Mvan_1003|M.vanbaalenii_PYR-1 VLERPLLDVVFDAD------GGEALRHTSYAQPALYAVEMGLARLWQSWG
Mb2971c|M.bovis_AF2122/97 --------------------------------------------------
Rv2946c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MMAR_1762|M.marinum_M --------------------------------------------------
MUL_2005|M.ulcerans_Agy99 --------------------------------------------------
MAV_3108|M.avium_104 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK FEPDVVLGHSVGQYAAACVAGVLSLRDGARLMAERGRLFGSLPSGGRMAA
MAB_0939|M.abscessus_ATCC_1997 FEPDVVLGHSVGQYSAACVAEVFSLEDGARLIAERGRLFSSLPAGGRMAA
MSMEG_0408|M.smegmatis_MC2_155 FEPDVVVGHSVGQYSAACVAGVFDVEDGARLIAERGRLFGSLPAGGRMAA
Mvan_1003|M.vanbaalenii_PYR-1 IEPDVVLGHSVGQYAAACVAGVMGLEDGAVLLAERGRLFGSLPEGGRMAA
Mb2971c|M.bovis_AF2122/97 --------------------------------------------------
Rv2946c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MMAR_1762|M.marinum_M --------------------------------------------------
MUL_2005|M.ulcerans_Agy99 --------------------------------------------------
MAV_3108|M.avium_104 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK VFAAAERVEALTDEYPALSVAAYNGANTVLSGPATDLERAVAGLVADGVR
MAB_0939|M.abscessus_ATCC_1997 VFTDAERAERLTDEFPSLSVAAYNGANTVLSGPAQDLEKAIAALVADGVR
MSMEG_0408|M.smegmatis_MC2_155 VFTAPERAERLTDEYPSLSVAAYNGANTVLSGPAKDLESAVATLVADGVR
Mvan_1003|M.vanbaalenii_PYR-1 VFAPADRVESCTVDSPLLSVAAYNGDNTVLSGPAGDLERAVAGFSAAGVR
Mb2971c|M.bovis_AF2122/97 --------------------------------------------------
Rv2946c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MMAR_1762|M.marinum_M --------------------------------------------------
MUL_2005|M.ulcerans_Agy99 --------------------------------------------------
MAV_3108|M.avium_104 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK CDWLETSHAFHSALLDPILDDFESYARGITFTAPQRILIDNRTGAALGRS
MAB_0939|M.abscessus_ATCC_1997 CDFLETSHAFHSALLDPILDEFEAYANQFNYKTPQRILIDNRTGTALGRS
MSMEG_0408|M.smegmatis_MC2_155 CDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALGRS
Mvan_1003|M.vanbaalenii_PYR-1 CDWLDTSHAFHSALLDPVLEEFESCADRFEFGTPQRTLVCNRSGEVLSRH
Mb2971c|M.bovis_AF2122/97 --------------------------------------------------
Rv2946c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MMAR_1762|M.marinum_M --------------------------------------------------
MUL_2005|M.ulcerans_Agy99 --------------------------------------------------
MAV_3108|M.avium_104 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK VTLDAAYWRRHARQPVEFAKSVHTLADMNCKLLVEIGPRPVLTAAALSAW
MAB_0939|M.abscessus_ATCC_1997 VKLDGAYWRRHARQPVEFAKSVRTLADMNCKVLLEIGPQPVLTAAALRAW
MSMEG_0408|M.smegmatis_MC2_155 TRLDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAW
Mvan_1003|M.vanbaalenii_PYR-1 ARLDGQYWRRHARQPVRFAESVRTLADLGCRLLMEIGPQPVLTAAAMRTW
Mb2971c|M.bovis_AF2122/97 --------------------------------------------------
Rv2946c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MMAR_1762|M.marinum_M --------------------------------------------------
MUL_2005|M.ulcerans_Agy99 --------------------------------------------------
MAV_3108|M.avium_104 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK PDPATSPRVIASLRRTTADQRQITEAVADAYVLGHLPRFAAFRRDGARVL
MAB_0939|M.abscessus_ATCC_1997 PDPATAPRAIASLRRNTADHRQITEAAADAYVLGHLPDFGAFQHAPARKL
MSMEG_0408|M.smegmatis_MC2_155 PDPATTPQVLASLRPTTADHRQITEAVAAAYAAGHLPDFRAFRQPDARKL
Mvan_1003|M.vanbaalenii_PYR-1 PGTVTAPRVAASMRRKGSDRRQITEALAQAYVAGHRPETAARQHGRGRLL
Mb2971c|M.bovis_AF2122/97 --------------------------------------------------
Rv2946c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MMAR_1762|M.marinum_M --------------------------------------------------
MUL_2005|M.ulcerans_Agy99 --------------------------------------------------
MAV_3108|M.avium_104 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK DLPTYPFEHRQYWFSDSRE---PVAAAPQR---GARTETVRLLEDGRIEE
MAB_0939|M.abscessus_ATCC_1997 DLPTYPFERRQYWFSDKRDGDNRDAGNRQQNNGGPRTEAVRLLEDGKIEE
MSMEG_0408|M.smegmatis_MC2_155 DLPTYPFEHRQFWFSDNRAIDRDTQTASAGSVTPHRTQAVRLLEDGQIEE
Mvan_1003|M.vanbaalenii_PYR-1 DLPTYPFQHRAYWFP--------QGQARTAPTDPVHTETVRFLDEERIDE
Mb2971c|M.bovis_AF2122/97 --------------------------------------------------
Rv2946c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MMAR_1762|M.marinum_M --------------------------------------------------
MUL_2005|M.ulcerans_Agy99 --------------------------------------------------
MAV_3108|M.avium_104 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK LAALLGGTVDDPFTFDVLNRLAAQHNQQRSTESIADDRYQIRWETAAEPP
MAB_0939|M.abscessus_ATCC_1997 LANLLGGVDGDQQTLNVLTKLAAQHNLQRTTQTIADDRYQFRWEKSPTPL
MSMEG_0408|M.smegmatis_MC2_155 LAALIDGETVDEQTLRVLNKLAARHNQQRSTHVDPDARYEIRWDAIASAA
Mvan_1003|M.vanbaalenii_PYR-1 LAALLDGPTGSAQTVDVLSKLAARHRQQRGAQSIADARYQIRWEKSEAPG
Mb2971c|M.bovis_AF2122/97 --------------------------------------------------
Rv2946c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MMAR_1762|M.marinum_M --------------------------------------------------
MUL_2005|M.ulcerans_Agy99 --------------------------------------------------
MAV_3108|M.avium_104 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK VGADAADGITWLLVGDDTDATRPLVDVLAARGHRYRILGLPKSGAEEHEL
MAB_0939|M.abscessus_ATCC_1997 SGSQAAGGVTWLLVADAAGAAQPLLDVLTARGQQHRVLALPVSDADEAEL
MSMEG_0408|M.smegmatis_MC2_155 ASTGAAA--DWILVGDDTAAVLEFADALTAGGHRHQIVALPGSDADEAQL
Mvan_1003|M.vanbaalenii_PYR-1 AARPTTEATTWLLVTHDSRAAQPIAEVLERRGHPYHIVGLPGSDADAAPA
Mb2971c|M.bovis_AF2122/97 --------------------------------------------------
Rv2946c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MMAR_1762|M.marinum_M --------------------------------------------------
MUL_2005|M.ulcerans_Agy99 --------------------------------------------------
MAV_3108|M.avium_104 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK ADTLRDAAADATDLRIVHVAALDAAESDTSMKSLLRMQHRVLGGTRRLFG
MAB_0939|M.abscessus_ATCC_1997 VEALRSAADEDSALRIVHVAALAGQGS-SSAQSLLRIQHQVLGGTRRLFR
MSMEG_0408|M.smegmatis_MC2_155 VDTLRAASAG--ELYVVHIAAGDGAAA--PMRDLLRVQHRTLGGLRRLFR
Mvan_1003|M.vanbaalenii_PYR-1 EEALRATVSQ-PRPHILYLAALEEPGG-SAAETLGWMQHRVLAAARRLFQ
Mb2971c|M.bovis_AF2122/97 --------------------------------------------------
Rv2946c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MMAR_1762|M.marinum_M --------------------------------------------------
MUL_2005|M.ulcerans_Agy99 --------------------------------------------------
MAV_3108|M.avium_104 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK AAVAAQLRSPMWLVTRGAQHVTDTDVVAPDQTCLWGFGRAASLEHPQIWG
MAB_0939|M.abscessus_ATCC_1997 AAAAAELRAPIWIVTRGAQHVIEGDTVAPEQSALWGFGRAAALELPQVWG
MSMEG_0408|M.smegmatis_MC2_155 AANDAELRSPIWLVTRDGQRVTDTDTVVPEQSCLWGFGRAAALELPHIWG
Mvan_1003|M.vanbaalenii_PYR-1 LAATAGARAPIWLITAGAQRITGDETVEPAQTSLWGFGRAAALEQPELWG
Mb2971c|M.bovis_AF2122/97 --------------------------------------------------
Rv2946c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MMAR_1762|M.marinum_M --------------------------------------------------
MUL_2005|M.ulcerans_Agy99 --------------------------------------------------
MAV_3108|M.avium_104 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK GLADLGGGTSDEWSRLLNRIAATHDPAVMEDQVAVRGSTSYVPRLVHRDT
MAB_0939|M.abscessus_ATCC_1997 GLADLSDAGTDEWAQFIGRVSVSGEASTREDQLALRGQAVHVPRLVRREE
MSMEG_0408|M.smegmatis_MC2_155 GLADLSGADT-EWPRLIARITSPRDG---EDQIALRGDAVYAPRLVRRTG
Mvan_1003|M.vanbaalenii_PYR-1 GLADVTTGDAEEWSALIDHIVAAPTS---EDQIAVRGREIHVARLTRCAE
Mb2971c|M.bovis_AF2122/97 --------------------------------------------------
Rv2946c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MMAR_1762|M.marinum_M --------------------------------------------------
MUL_2005|M.ulcerans_Agy99 --------------------------------------------------
MAV_3108|M.avium_104 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK LPSGKPLHLRADATYLVTGGLGSLGLEIAGYLAANGAGHLVLTSRRTPDE
MAB_0939|M.abscessus_ATCC_1997 LPSGKPLEVRSDATYLVTGGLGSIGLEIAGYLAGRGAKHLVLTSRREPGE
MSMEG_0408|M.smegmatis_MC2_155 EPSDTPLPVREDRTYLVTGGLGAIGLEVAGYLASHGAGHVVLTSRREPGD
Mvan_1003|M.vanbaalenii_PYR-1 KANAAALELRREATYLVTGGLGALGLEVAEFLASHGAGHLVLTGRRSASD
Mb2971c|M.bovis_AF2122/97 --------------------------------------------------
Rv2946c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MMAR_1762|M.marinum_M --------------------------------------------------
MUL_2005|M.ulcerans_Agy99 --------------------------------------------------
MAV_3108|M.avium_104 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK AAASRIEALRERHGCEVRVVTADVADAHAVARLLATVQAEMPPLAGIVHA
MAB_0939|M.abscessus_ATCC_1997 AARQRIDALAA-QGCEVRAVTADVADGHDVARLLAGIQAELPPLAGIVHA
MSMEG_0408|M.smegmatis_MC2_155 DARRRLDGLREQYACDVRVITADVADAHDVARLMTTVAAELPPLAGIVHA
Mvan_1003|M.vanbaalenii_PYR-1 TVRQRIDAMRERFDCQVLVATADVADRDDVARLFSTMRSELPPLAGIVHA
Mb2971c|M.bovis_AF2122/97 --------------------------------------------------
Rv2946c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MMAR_1762|M.marinum_M --------------------------------------------------
MUL_2005|M.ulcerans_Agy99 --------------------------------------------------
MAV_3108|M.avium_104 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK AGEIGTTPLADLDDAEVDRVFAGKVWGAWHLSEATSDLQ--LDFFISTSS
MAB_0939|M.abscessus_ATCC_1997 AGEIGTTPLSDLEDAEVDRVFAGKVWGAWHLSEAAAGLK--LDFFINTSS
MSMEG_0408|M.smegmatis_MC2_155 AGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEALTDLRTDLDFFVSTSS
Mvan_1003|M.vanbaalenii_PYR-1 AGEIGTSPLRTLDDAEMDRVFAGKVWGAVYLCEEVADMG--LDFFLATSS
Mb2971c|M.bovis_AF2122/97 --------------------------------------------------
Rv2946c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MMAR_1762|M.marinum_M --------------------------------------------------
MUL_2005|M.ulcerans_Agy99 --------------------------------------------------
MAV_3108|M.avium_104 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK IASVWGGFGQAAYGAANAFLDGLAWRLREQGVAGVSVNFGPWSAGMADAQ
MAB_0939|M.abscessus_ATCC_1997 IAAVWGGYGQTAYSAANAFLDGLAWRLREQGIAGTSVNFGPWSAGMADAE
MSMEG_0408|M.smegmatis_MC2_155 IASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPWAAGMADAE
Mvan_1003|M.vanbaalenii_PYR-1 IASVWGSHGQTAYGAANAFLDGLADSLRARGIPGISVNFGPWAAGMADAK
Mb2971c|M.bovis_AF2122/97 --------------------------------------------------
Rv2946c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MMAR_1762|M.marinum_M --------------------------------------------------
MUL_2005|M.ulcerans_Agy99 --------------------------------------------------
MAV_3108|M.avium_104 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK SRARLEQRGIKTLSPADALAGLSDAVISAAP---HPVVARVDWSRFLPLY
MAB_0939|M.abscessus_ATCC_1997 SRARLEQRGIKTLSPTDALAGLADVVAASGSNAVQGVIARIDWARFLPLY
MSMEG_0408|M.smegmatis_MC2_155 SRARLEQRGVRTLSPAEALAGMADVVAGPVQ----GVVAKIDWSRFLPLY
Mvan_1003|M.vanbaalenii_PYR-1 AREQLSRRGVKTLAPADALAGMADVIAASTA---HAVVARIDWATFLPVY
Mb2971c|M.bovis_AF2122/97 --------------------------------------------------
Rv2946c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MMAR_1762|M.marinum_M --------------------------------------------------
MUL_2005|M.ulcerans_Agy99 --------------------------------------------------
MAV_3108|M.avium_104 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK QQAGRRGFLAELERELPAAPAQQGPAVTASGRTPLVERLTTAPLQQRKRL
MAB_0939|M.abscessus_ATCC_1997 QQAGKRGFLAELDREVPSHLA--GVAGAQSGSTQLVERLANAPVQQRKKL
MSMEG_0408|M.smegmatis_MC2_155 QQAGRRAFLSELESELPAAATGAAAPATVPGKPPLVEQLTKAPVQQRKSL
Mvan_1003|M.vanbaalenii_PYR-1 QLQRRRAFLSQLEREVPDVPD--ASAPAPSGTTRFVEELTLAPVEQRRKL
Mb2971c|M.bovis_AF2122/97 -------------------------------MIEEQRTMSVEGADQQSEK
Rv2946c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00135|M.leprae_Br4923 ------------------------------------MTASVEGADQKSEK
MMAR_1762|M.marinum_M ------------------------------------MTTSGESADQQNDK
MUL_2005|M.ulcerans_Agy99 ------------------------------------MTTSGESADQQNDK
MAV_3108|M.avium_104 --------------------------------------------MPGTEQ
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK LTDYLRDAVAEVTRVDAAEIREDAGFFDLGMDSLMAVELRRRIETGVGKE
MAB_0939|M.abscessus_ATCC_1997 LTDYLRDAVAEVTRVDVSEIREDAGFFDLGMDSLMAVELRRRMEQGVGKE
MSMEG_0408|M.smegmatis_MC2_155 ITNYLRNAVAEVTRVDADEIRDEAGFFDLGMDSLMAVELRRRIEQGVGKD
Mvan_1003|M.vanbaalenii_PYR-1 VLEYLRAAVAEVTRVDAAEIRDEAGFFDLGMDSLMAIELRRRLEQGLGKE
Mb2971c|M.bovis_AF2122/97 LFHYLKKVAVELDETRARLREYEQ--------------------------
Rv2946c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00135|M.leprae_Br4923 LISYLKKVVVELDETRARLREYEQ--------------------------
MMAR_1762|M.marinum_M LFRYLKKVAVELDEARARLREYEQ--------------------------
MUL_2005|M.ulcerans_Agy99 LFRYLKKVAVELDEARARLREYEQ--------------------------
MAV_3108|M.avium_104 HLDYLKRLTADLRRTRRRVAELEG--------------------------
TH_4621|M.thermoresistible__bu -VNIVGDTPVN---------------------------------------
Mflv_0405|M.gilvum_PYR-GCK IPVTLVMDHPRLSDAADYLLGDVLGLTEAAT-APKAATVVSTAADEPIAI
MAB_0939|M.abscessus_ATCC_1997 IPVTLVMDHPRISDVADYLLGDVLGLAEQAKPAAQLASAVTGRTDEPIAI
MSMEG_0408|M.smegmatis_MC2_155 IPVTLVMDHPRLSDAADYLLVEVLGLGEQTN--VRQASTVTARTDDPIAV
Mvan_1003|M.vanbaalenii_PYR-1 LPVTLAMDHPHLSDAAEYVLGDVLGLSEHTV--AQPDTPSTVRTDDPIAI
Mb2971c|M.bovis_AF2122/97 ------------------------------------------RATEPVAV
Rv2946c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00135|M.leprae_Br4923 ------------------------------------------RATEPVAV
MMAR_1762|M.marinum_M ------------------------------------------RATEPVAV
MUL_2005|M.ulcerans_Agy99 ------------------------------------------RATEPVAV
MAV_3108|M.avium_104 ------------------------------------------RLSEPVAV
TH_4621|M.thermoresistible__bu ----------------------------------------------AVAV
Mflv_0405|M.gilvum_PYR-GCK VAVSCRFPG-APNPEAFWDLLSGGVDAIREVPEDR-FDIDEFYDPDPDAA
MAB_0939|M.abscessus_ATCC_1997 VAVSCRFPG-APDPEAFWDVLSGGVDAIREVPEDR-FDIDEFYDPDPEVA
MSMEG_0408|M.smegmatis_MC2_155 VAVSCRFPG-APDPESFWELLAGGVDAIREVPEDR-WDIDEFYDPDPDTP
Mvan_1003|M.vanbaalenii_PYR-1 VGMACRFPG-ADDTDAFWSVLAEGADLIREIPDDR-FDINEFYDPDPEAA
Mb2971c|M.bovis_AF2122/97 VGIGCRFPGGVDGPDGLWDVVSAGRDVVSEFPTDRGWDVEGLYDPDPDAE
Rv2946c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00135|M.leprae_Br4923 VGIGCRFPGGVDSPDRLWDVVSECRDVVSEFPTDRGWDVDGLFDPDPDAE
MMAR_1762|M.marinum_M VGIGCRFPGGADGPEGLWDLVSQGRDAVTEFPNDRGWDTEGLFDPDPDAE
MUL_2005|M.ulcerans_Agy99 VGIGCRFPGGADGPEGLWDLVSQGRDAVTEFPNDRGWDTEGLFDPDPDAE
MAV_3108|M.avium_104 VGMACRYAGGVDSPEALWDLVIEGRDTVSDFPVDRGWDVEGLYDPDPDAK
TH_4621|M.thermoresistible__bu IGMACRLPGGIDSPQRLWEALLRGDDMVTEIPVDR-WDADDYFDPEPGVP
Mflv_0405|M.gilvum_PYR-GCK GKTYTRYGGFLDHIDEFDPEFFGLSPREAVWIEPQQRLMLETVWEGLERA
MAB_0939|M.abscessus_ATCC_1997 GKTYTRFGGFLDGIDGFDPEFFGISPREAVWIEPQQRLMLETVWEGLERA
MSMEG_0408|M.smegmatis_MC2_155 GKTYTRFGGFLDGIDGFDPEFFGISPREAVWIEPQQRLMLETVWEGLERA
Mvan_1003|M.vanbaalenii_PYR-1 GKIYSRYGGFLDGVDGFDPEFFGISPREAVWIDPQQRLVLETAWEGLERA
Mb2971c|M.bovis_AF2122/97 GKTYTRWGAFLDDATGFDAGFFGIAPSEVLAMDPQQRLMLEVSWEALEHA
Rv2946c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00135|M.leprae_Br4923 GKTYTRWGAFLDDAAGFDAGFFGIAPSEVLAMDPQQRLMLEVSWEALEYA
MMAR_1762|M.marinum_M GKTYTRWGAFVENATNFDAGFFGIPPSEVLAMDPQQRLMLEVSWEALEHA
MUL_2005|M.ulcerans_Agy99 GKTYTRWGAFVENATNFDAGFFGIPPSEVLAMDPQQRLMLEVSWEALEHA
MAV_3108|M.avium_104 GKMYTRQGSFLQHAGDFDAGFFGIGPSEALAMDPQQRIMLEICWEALERA
TH_4621|M.thermoresistible__bu GRTVSRWGAFLDDVAGFDPEFFGISEREAISIDPQQRLLLETSWEAMEHA
Mflv_0405|M.gilvum_PYR-GCK GYAPSALRGSRTGVFVGVAANEYAHLLSAESIDKIEPHFITGNALNAISG
MAB_0939|M.abscessus_ATCC_1997 GYSPAALRGSRTGIFAGVGANEYAHLLSSESIDKIEPYFITGNALNAISG
MSMEG_0408|M.smegmatis_MC2_155 GYAPSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISG
Mvan_1003|M.vanbaalenii_PYR-1 GYSAAALRGSRSGVYVGVGANEYSHLLSGGSLDGIEAQFITGNALNVIAG
Mb2971c|M.bovis_AF2122/97 GIDPLSLRGSATGVYTGIFAASYGNRDTG----GLQGYGLTGTSISVASG
Rv2946c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00135|M.leprae_Br4923 GIDPLSLRGSATGVFTGIFAPSYGSRDTG----GLQGYGLTGTAVSVASG
MMAR_1762|M.marinum_M GIDPMSLRGSSTGVFTGIFAPSYGGKDVG----ALQGYGLTGSPVSVASG
MUL_2005|M.ulcerans_Agy99 GIDPMSLRGSSTGVFTGIFAPSYGGKDVG----ALQGYGLTGSPVSVASG
MAV_3108|M.avium_104 GIDPSALRGTATGVFAGVIHAGYGGEVKG----ELEGYGLTGSTLSVTSG
TH_4621|M.thermoresistible__bu GLTPADVEGSSTGVFVGLSHDDYALLTSDAG-ALEEAYGFTGSAFSMASG
Mflv_0405|M.gilvum_PYR-GCK RVAFALGLEGPAVAVDTACSSSLVAVHQATQALRSGDCDMALAGGVNVLL
MAB_0939|M.abscessus_ATCC_1997 RVAFALGFEGPAVAVDTACSSALVAVHQAVQALHSGDCDLALAGGVNVLL
MSMEG_0408|M.smegmatis_MC2_155 RVAFALGFEGPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLL
Mvan_1003|M.vanbaalenii_PYR-1 RVSFTLGLEGPAVAVDTACSSSLVAVHQACQGLQSGDCDLALAGGVNVLL
Mb2971c|M.bovis_AF2122/97 RVSYVLGLQGPAVSVDTACSSSLVAIHWAMSSLRSGECDLALAGGVTVMG
Rv2946c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00135|M.leprae_Br4923 RVSYVLGLEGPAVSVDTACSSSLVAIHWAMSSLRSGECDLALAGGVTVMG
MMAR_1762|M.marinum_M RVAYVLGLEGPALSVDTACSSSLVAIHWAMASLRSGECDMALAGGVTVMG
MUL_2005|M.ulcerans_Agy99 RVAYVLGLEGPALSVDTACSSSLVAIHWAMASLRSGECDMALAGGVTVMG
MAV_3108|M.avium_104 RVSYVLGLEGPAVSVDTACSSSLVAMHLAAQSLRSGECDLALAGGVTVMA
TH_4621|M.thermoresistible__bu RIAYRLGVHGPAVTVDTACSSSLLAVHMACRSLQVGESDLALAGGAMVML
Mflv_0405|M.gilvum_PYR-GCK SPVTVVAASRARMLSPVGRCKTFDASADGYVRSEGCGILVLKRLSDAVRD
MAB_0939|M.abscessus_ATCC_1997 SPVTVIAASRARMLSPVGRCKTFDASADGYVRSEGCGILVLKRLSDAERD
MSMEG_0408|M.smegmatis_MC2_155 SPVTVVAASRARMLSPVGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRD
Mvan_1003|M.vanbaalenii_PYR-1 SPATTIATSRARMLSPDGRCKTFDAAADGYVRGEGCGILVLKRLSDAVRD
Mb2971c|M.bovis_AF2122/97 LPSIFVGFSRQRGLAADGRCKAFAAAADGTGWGEGAGVVVLERLSDARRL
Rv2946c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00135|M.leprae_Br4923 LPSIFVGFSRQRGLAADGRCKAFARAADGTGWGEGAGVVVLERLSDAQRL
MMAR_1762|M.marinum_M LPSIFVGFSRQRGLAADGRCKAFAAAADGTGWGEGAGVLVLERLSDAQRN
MUL_2005|M.ulcerans_Agy99 LPSIFVGFSRQRGLAADGRCKAFAAAADGTGWGEGAGVLVLERLSDAQRN
MAV_3108|M.avium_104 TPAAFVEFSRQRALAPDGRCKVYAGAADGTSWSEGAGVLVLERLADARRL
TH_4621|M.thermoresistible__bu EPRKYTSASGLGMLSPTGRCHAFDVAADGFVRSEGSVMLLLKRLPDALRD
Mflv_0405|M.gilvum_PYR-GCK GDRVCAVIAGSAVNQDGASSGLTVPNGGAQQRLIGTVLARAGITGGEVDY
MAB_0939|M.abscessus_ATCC_1997 GDRVLAVIPGSAVNQDGASSGLTVPNGGAQQRLIGSVLARAGLVGGDVDY
MSMEG_0408|M.smegmatis_MC2_155 GDRVCAVIPASSVNQDGASSGLTVPNGGAQQRLIEATLARAGLSGADVDY
Mvan_1003|M.vanbaalenii_PYR-1 GDRIQAVIRGSAVNQDGASGGLTVPNGGAQQRVIAAALTRAGLSGSDIDY
Mb2971c|M.bovis_AF2122/97 GHSVLAVVRGSAVNQDGASNGLTAPNGLAQQRVIQAALANAGLSAADVDV
Rv2946c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00135|M.leprae_Br4923 GHTVLAVVRGSAVNQDGASNGLTAPNGLAQQRVIQAALTNAGLSSADVDV
MMAR_1762|M.marinum_M GHNVLAVVRGSAINQDGASNGLTAPNGLAQQRVIQAALANCGLTSADVDV
MUL_2005|M.ulcerans_Agy99 GHNVLAVVRGSAINQDGASNGLTAPNGLTQQRVIQAALANCGLTSADVDV
MAV_3108|M.avium_104 GHPVWAVLRGSAVNQDGASNGLTAPNGPSQQRVIRAALANAGLSAVDVDV
TH_4621|M.thermoresistible__bu NDRILAVVRGTAANQDGRTENISTPSIQAQADVYRSALAVAGVDPATVGM
Mflv_0405|M.gilvum_PYR-GCK LEAHGTGTPLGDPIEVQAAAAAYAGARDADRPLLMGSVKTNIGHTESASG
MAB_0939|M.abscessus_ATCC_1997 LEAHGTGTPLGDPIEVQAAAAAYGGSRDADRPLLMGSVKSNIGHTESASG
MSMEG_0408|M.smegmatis_MC2_155 LEAHGTGTPLGDPIEVQAAAAAYGAGRDADRPLLMGSVKTNIGHTESASG
Mvan_1003|M.vanbaalenii_PYR-1 LEAHGTGTSLGDPIEVQAAGAVLGAGRDPDRPLLMGSVKTNVGHLESASG
Mb2971c|M.bovis_AF2122/97 VEAHGTATTLGDPIEAQALLSTYGQGRPAEQPLWVGSIKSNMGHTQAAAG
Rv2946c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00135|M.leprae_Br4923 VEAHGTATTLGDPIEAQALLATYGQGRPADQPLWVGSIKSNMGHTQAAAG
MMAR_1762|M.marinum_M VEAHGTATTLGDPIEAEALLATYGQGRPTDQPLWVGSIKSNMGHTQAAAG
MUL_2005|M.ulcerans_Agy99 VEAHGTATTLGDPIEAEALLATYGQGRPTDQPLWVGSIKSNMGHTQAAAG
MAV_3108|M.avium_104 VEGHGTGTVLGDPIEAQALLATYGQDRPADRPLWLGSIKSNIGHTSAAAG
TH_4621|M.thermoresistible__bu VEAHGTGTPVGDPIEYNSLTQVYGKTG----PCALTSVKTNFGHAESAAG
Mflv_0405|M.gilvum_PYR-GCK AAGLIKVVLSLQHETLPQSLHFDTPSPHIPWDSLPVRVVDTAMPWQP-NG
MAB_0939|M.abscessus_ATCC_1997 AAGLIKVVLSLQNGVLPQSLHFDNPSPHIPWESLPVRVVDKAIPWQA-NG
MSMEG_0408|M.smegmatis_MC2_155 AAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQT-NG
Mvan_1003|M.vanbaalenii_PYR-1 VAGLIKVVLSLQHEMLPRHLHFKTPSPHIPWDRLAVRVVAEPTPWRA-DG
Mb2971c|M.bovis_AF2122/97 VAGVIKMVQAMRHGVMPATLHVDEPSPRVDWTSGAVSVLTEAREWSV-DG
Rv2946c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00135|M.leprae_Br4923 VAGVIKMVQAMRHHVMPATLHVDEPSPRVDWTTGAVSVLTEARDWSV-EG
MMAR_1762|M.marinum_M VAGVIKMVQAMRHGLMPASLHVDEPSKRVDWESGAVSVLAEARDWPD-AG
MUL_2005|M.ulcerans_Agy99 VAGVIKMVQAMRHGLMPASLHVDEPSKRVDWESGAVSVLAEARDWPD-AG
MAV_3108|M.avium_104 VAGVIKMVQALRHGVMPKTMHVDVPSPHVDWSAGAVSLLTDPRPWPE-HG
TH_4621|M.thermoresistible__bu ALGMMKAILALQHGVVPQNLHFTRLPDEMAAIETNLFVPQATTLWPVREG
Mflv_0405|M.gilvum_PYR-GCK RPRRAGVSSFGFTGTNAHVLIEEAPTDLAGPTEPTAPAEPVDEDAAADPA
MAB_0939|M.abscessus_ATCC_1997 RPRRAGVSSFGFTGTNAHVLIEEAPQPQATP----------DEDDASTPQ
MSMEG_0408|M.smegmatis_MC2_155 RVRRAGVSSFGFTGTNAHVLVEEAPPQLHTADAAP----VEPAATAEAGT
Mvan_1003|M.vanbaalenii_PYR-1 RPRRAGVSSFGFSGTNAHVVLEEPPAQSADLRQPPTDGKDGAAGLESATA
Mb2971c|M.bovis_AF2122/97 RPRRAAVSSFGISGTNAHLILEEAPVPAPAEAPVE-------ASESTGGP
Rv2946c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00135|M.leprae_Br4923 RPRRAGVSSFGISGTNAHVILEEAPTPVEASYSTA-------DQQ-----
MMAR_1762|M.marinum_M RPRRAGVSSFGISGTNAHVILEEAPAPEAVPDSES-------NKGE---P
MUL_2005|M.ulcerans_Agy99 RPRRAGVSSFGISGTNAHVILEEAPAPEAVPDSES-------NKGE---P
MAV_3108|M.avium_104 GPRRAGVSSFGISGTNAHVIVEQAPAAAETEAAPA-------SSTMP---
TH_4621|M.thermoresistible__bu CPRRAAVSSYGMSGTNVHAVLEQAPEPVQRPEESAD------------TD
Mflv_0405|M.gilvum_PYR-GCK PAPVEVLPLSARSPEALVALAQRYETWLTAH-PEADLADVCRTAGTGRSH
MAB_0939|M.abscessus_ATCC_1997 SAPVSVLPLSARSPEALAAVAQRYESWLAAH-PDVDLEDVCLTAGRGRSH
MSMEG_0408|M.smegmatis_MC2_155 DDSPQVLALSARSPEALVELARRYDDWLSAT-PGLDIADVCHTAGVGRSH
Mvan_1003|M.vanbaalenii_PYR-1 PEPAGVLPISARSPEALTALARRYESWLTAH-PDADIADVCYTAGAGRSH
Mb2971c|M.bovis_AF2122/97 RPSMVPWVISARSAEALTAQAGRLMAHVQAN-PGLDPIDVGCSLAS-RSV
Rv2946c|M.tuberculosis_H37Rv -------MISARSAEALTAQAGRLMAHVQAN-PGLDPIDVGCSLAS-RSV
MLBr_00135|M.leprae_Br4923 RLSVVPWVVSGRSTAALMAQASRLAFYVQAD-PEVDPVDVGCALAA-RSV
MMAR_1762|M.marinum_M SLPVVPWVISARSAEALTAQAGRLLAHVQAD-PQSNPVDIGFSLAG-RSA
MUL_2005|M.ulcerans_Agy99 SLPVVPWVISARSAEALTAQAGRLLAHVQAD-PQSNPVDIGFSLAG-RSA
MAV_3108|M.avium_104 -DAVVPWVVSARSAEALAGQARRLLDHVTAD-AQASPLDVGWSLVSTRAV
TH_4621|M.thermoresistible__bu AAGPLVFALSSTSAEELRRTAGRLAEWVEAHTDEVVPADLAYTLARRRAH
:*. *. * * * : * *: : *:
Mflv_0405|M.gilvum_PYR-GCK FEHRAALVVDSVESARIALTDLAQNRLRPGVVRGEHLNHPTTAWMFTGQG
MAB_0939|M.abscessus_ATCC_1997 FEHRAALVVDSIQTAREGLLELAQNRLRPGVVRGEHTNHPTTAWLFTGQG
MSMEG_0408|M.smegmatis_MC2_155 FEYRAALVVDSVERAREGLAALAEGRTPAGVVRGEHVHRPTTAWLFTGQG
Mvan_1003|M.vanbaalenii_PYR-1 FEHRAALVVDSVDGARDLLAGLAEDRLGPGAVRGVCGDPPKTAWLFTGQG
Mb2971c|M.bovis_AF2122/97 FEHRAVVVGASREQLIAGLAGLAAGEPGAGVAVGQPGSVGKTVVVFPGQG
Rv2946c|M.tuberculosis_H37Rv FEHRAVVVGASREQLIAGLAGLAAGEPGAGVAVGQPGSVGKTVVVFPGQG
MLBr_00135|M.leprae_Br4923 FEHRAVVVGESREQLIAGLAGLAVGESGAGVAIGQAAPLGKTVVVFPGQG
MMAR_1762|M.marinum_M FEHRAVVVGADRQQLLTGLATLADGAPGAGVVTGQAGSVGKTAVVFPGQG
MUL_2005|M.ulcerans_Agy99 FEHRAVVVGADRQQLLTGLATLADGAPGAGVVTGQAGSVGKTAVVFPGQG
MAV_3108|M.avium_104 FEHRAVVVGRERGALATGLAGLASGRPGPATVVGRARSTGKTVLVFPGQG
TH_4621|M.thermoresistible__bu RPVRTTVIADGVEALTAGLREVADGDAPYQPAVGMDDKAP--VWVFSGQG
*:.:: * :* . . * . :*.***
Mflv_0405|M.gilvum_PYR-GCK SQYPGMARELFDTEPVFADTVTRCADAVADLLPRPLLDVMFAGGREAGVP
MAB_0939|M.abscessus_ATCC_1997 SQYPGMARELFDAEPVFAETVTRCAEAVKDIVTRPLLEVMFATDRETGGK
MSMEG_0408|M.smegmatis_MC2_155 SQYPGMARELFDTQPVFAQTVRQCAEAVADMLPRPLLDVLFATDRET---
Mvan_1003|M.vanbaalenii_PYR-1 SQYPGMARELFDTEPVFRDTVTRCAEAIGDTLPRPLLEVLFDTDGDN---
Mb2971c|M.bovis_AF2122/97 AQRIGMGRELYGELPVFAQAFDAVADELDRHLRLPLRDVIWGADADL---
Rv2946c|M.tuberculosis_H37Rv AQRIGMGRELYGELPVFAQAFDAVADELDRHLRLPLRDVIWGADADL---
MLBr_00135|M.leprae_Br4923 AQRIGMGRELCSQLPVFAEEFDAVTGELDRHMRLPLRDVVWGADAGL---
MMAR_1762|M.marinum_M SQRIGMARELHDQLPVFAEAFDAVADELDRHLRIPLREVMWGSDAAL---
MUL_2005|M.ulcerans_Agy99 SQRIGMARELHDQLPVFAEAFDAVADELDRHLRIPLCEVMWGSDVAL---
MAV_3108|M.avium_104 SQTLGMGRQLYERFEVFAGALDEAVAVVDEHSRLSVREVMWGADPEL---
TH_4621|M.thermoresistible__bu SQWAGMGAELLATEQVFAAKIAEIEPLVARESGFSVTEAMTASETVTG--
:* **. :* ** . : .: :.:
Mflv_0405|M.gilvum_PYR-GCK PTETLRHTSFAQPALFAVEMGLARLWQSWGIVPDVVLGHSVGQYAAACVA
MAB_0939|M.abscessus_ATCC_1997 AGEALRHTSFAQPALFAVEMGLARLWQSWGIEPDVVLGHSVGQYAAACVA
MSMEG_0408|M.smegmatis_MC2_155 -ADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACVA
Mvan_1003|M.vanbaalenii_PYR-1 -GQTLRHTSYAQPALFAIEMGLARLWQARGIEPDVVLGHSVGQYAAACVA
Mb2971c|M.bovis_AF2122/97 ----LDSTEFAQPALFAVEVASFAVLRDWGVLPDFVMGHSVGELAAAHAA
Rv2946c|M.tuberculosis_H37Rv ----LDSTEFAQPALFAVEVASFAVLRDWGVLPDFVMGHSVGELAAAHAA
MLBr_00135|M.leprae_Br4923 ----LDSTEFAQPALFAVEVALFAVLQHWGLQPDFVMGHSIGELAAAYVA
MMAR_1762|M.marinum_M ----LDSTEFAQPALFAVEVALFAALQRWGLQPDFVMGHSVGELSAAYVA
MUL_2005|M.ulcerans_Agy99 ----LDSTEFAQAALFAVEVALFAALQRWGLQPDFVMGHSVGELSAAYVA
MAV_3108|M.avium_104 ----LQSTEFAQPALFVFEVALAALWESLGVTPDVVMGHSVGEIAAACVA
TH_4621|M.thermoresistible__bu -------IDRVQPTLFAIQVALAATMQSYGVRPGAVIGHSLGEVAAAVVA
. .*.:**..::. . .: *. *:***:*: :** .*
Mflv_0405|M.gilvum_PYR-GCK GVFSLEDGARLMAERGRLFGSLPEGGRMVAVFADAKRVEQVAADFPR--V
MAB_0939|M.abscessus_ATCC_1997 GVFSIEDGARLIAERGRLFGGLPAGGRMVAVFSDAKHVEQIAGEFPR--V
MSMEG_0408|M.smegmatis_MC2_155 GVFSLDDGARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAGEFPR--V
Mvan_1003|M.vanbaalenii_PYR-1 GVFGLEDGARLVADRGRLFGGLPVGGRMVAVFTDAEVVEDFADEFPQ--V
Mb2971c|M.bovis_AF2122/97 GVLTLADAAMLVVARGRLMQALPAGGAMVAVAASEDEVEPLLGEG----V
Rv2946c|M.tuberculosis_H37Rv GVLTLADAAMLVVARGRLMQALPAGGAMVAVAASEDEVEPLLGEG----V
MLBr_00135|M.leprae_Br4923 GVLAPADAAMLVVARGRLMQSMPAGGTMWAVAASEDEVVSLLGEG----V
MMAR_1762|M.marinum_M GVLTLADAAMLVVARGRLMQALPAGGAMVAVAAAEDEVLPSLTDG----V
MUL_2005|M.ulcerans_Agy99 GVLTLVDAAMLVVARGRLMQALPAGGAMVAVAAAEDEVLPSLTDG----V
MAV_3108|M.avium_104 GVLSLRDAARLVAARGALMAALPPGGVMVAVTAGESQVGPLLGGG----V
TH_4621|M.thermoresistible__bu GALSLEDGVKVICRRSRLCLRLAGAGAMAAIELPAQAVREFLAARGVDDV
*.: *.. :: *. : :. .* * *: . * *
Mflv_0405|M.gilvum_PYR-GCK SVGAYNGP-NTVLSGPGEDLEQIVGTFGEDGIRCTWLETSHAFHSELLDP
MAB_0939|M.abscessus_ATCC_1997 SVGAYNGP-NTVLSGPGEDLEQAVARFQEEGIRCTWLETSHAFHSELLDP
MSMEG_0408|M.smegmatis_MC2_155 SVGAYNGP-NTVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDP
Mvan_1003|M.vanbaalenii_PYR-1 SVAAYNGP-NTVLAGPASDLEQIVAGCSGEGIRTTWLDTSHAFHSALLDP
Mb2971c|M.bovis_AF2122/97 GIAAINAPESVVISGAQAAANAIADRFAAQGRRVHQLAVSHAFHSPLMEP
Rv2946c|M.tuberculosis_H37Rv GIAAINAPESVVISGAQAAANAIADRFAAQGRRVHQLAVSHAFHSPLMEP
MLBr_00135|M.leprae_Br4923 GIAAINAPESVVISGPQAAVSAIADKFAAQGRRVHQLAVSHAFHSPLMEP
MMAR_1762|M.marinum_M GIAAINAPKSVVISGAEAAVTAISDQFAQQGRRVHRLAVSHAFHSPLMEP
MUL_2005|M.ulcerans_Agy99 GIAAINAPKSVVISGAEAAVTAISDQFAQQGRRVHRLAVSHAFHSPLMEP
MAV_3108|M.avium_104 SIAAVNGPDAVVLSGEQEAVAAVADRLAGSGARVHRLAVSHAFHSALMEP
TH_4621|M.thermoresistible__bu VLSVIASPESTVIGGATDTVRELVAAWEAQGVMAREVAVDVASHSPQVDP
:.. .* .*:.* .* : .. * ** ::*
Mflv_0405|M.gilvum_PYR-GCK VLDEFESYAAQLQFAAPTLPLVCNRTGAVLTGQT-SLDAQYWRRHSRQPV
MAB_0939|M.abscessus_ATCC_1997 ILDEFESYAAQVQFAAPTLPLVCNRTGAVLTAQT-PIDGQYWRRHSRQPV
MSMEG_0408|M.smegmatis_MC2_155 VLDEFEAYAAQFQFAAPTLPLVCNRTGAVLTGQT-PLDAQYWRRHSRQPV
Mvan_1003|M.vanbaalenii_PYR-1 VLDEFESCAARLAYAAPTRPLVCNRTGAVVTGPG-VIDAQYWRRHARQPV
Mb2971c|M.bovis_AF2122/97 MLEEFARVAARVQAREPQLGLVSNVTGELAGPD--FGSAQYWVDHVRRPV
Rv2946c|M.tuberculosis_H37Rv MLEEFARVAARVQAREPQLGLVSNVTGELAGPD--FGSAQYWVDHVRRPV
MLBr_00135|M.leprae_Br4923 MLEEFVRVAAQVEVRKPQIGLVSNVTGELAGPD--FGSPQYWGEHVSRAV
MMAR_1762|M.marinum_M MLEEFARIAAQVEAREPQIALVSNVTGELASADGGFGSAQYWVEHVRRAV
MUL_2005|M.ulcerans_Agy99 MLEEFARIAAQVEAREPQIALVSNVTGELASADGGFGSAQYWVEHVRRAV
MAV_3108|M.avium_104 MLDGFAAAAAGIEPRPPRIPLVSNLTGQLAGPG--YGTPQYWVDHVRRPV
TH_4621|M.thermoresistible__bu ILDELEEILADLQPMTPTVPYYSATSYDPREKP--VCDADYWVDNLRHEV
:*: : * . * . : :** : : *
Mflv_0405|M.gilvum_PYR-GCK QFAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHLAAPRAIASLRKG
MAB_0939|M.abscessus_ATCC_1997 QFAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHLAPPRAIVSLRKG
MSMEG_0408|M.smegmatis_MC2_155 QFAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHMAAPRAVASLRKG
Mvan_1003|M.vanbaalenii_PYR-1 QFAESVRTLADLGCSVLMEIGPQPFLIAAALRVWPESAATPRAIPSLRKG
Mb2971c|M.bovis_AF2122/97 RFADSARHLQTLGATHFIEAGPGSGLTGSIEQSLAP--AEAMVVSMLGKD
Rv2946c|M.tuberculosis_H37Rv RFADSARHLQTLGATHFIEAGPGSGLTGSIEQSLAP--AEAMVVSMLGKD
MLBr_00135|M.leprae_Br4923 RFVDSARHLQTLGATHFIESGPSSGLMGAIEQSLAP--AEAVVVSMMGKD
MMAR_1762|M.marinum_M RFADSARQLHTLGVTHFVEVGPGSGLTGSIEQSLAP--AEAVVVSMLGKD
MUL_2005|M.ulcerans_Agy99 RFADSARQLHTLGVTHFVEVGPGSGLTGSIEQSLAP--AEAVVVSMLGKD
MAV_3108|M.avium_104 RFVDGVRLAESQGAGVFLEVGPGAALTSAVEQSLTS--DRAMSVVTMPKG
TH_4621|M.thermoresistible__bu RFAAAVQAALEDGFRVFGELSPHPLLTRAVEQTARGLDMPVAALPAMRRE
:*. ..: * : * .* . * : : : : :
Mflv_0405|M.gilvum_PYR-GCK VADRRQIADALAAAYIGGHKPDFAALHEQRG-VRLELPTYPFQRRRFWPK
MAB_0939|M.abscessus_ATCC_1997 VEDRRQIADALASAYVSGHRPNFAALQRHPR-RTVELPTYPFQRRRFWPK
MSMEG_0408|M.smegmatis_MC2_155 VADRRQIADALASAYVGGHRPDFAAVHRQPR-RPVELPTYPFQRRRFWPK
Mvan_1003|M.vanbaalenii_PYR-1 PDARRQLAEAVAAAYIAGHRLDFTGHDGGPH-RRLPLPTYPFQHRSYWPK
Mb2971c|M.bovis_AF2122/97 RPELASALGAAGQVFTTGVPVQWSAVFAGSGGRRVQLPTYAFQRRRFWET
Rv2946c|M.tuberculosis_H37Rv RPELASALGAAGQVFTTGVPVQWSAVFAGSGGRRVQLPTYAFQRRRFWET
MLBr_00135|M.leprae_Br4923 RPELASVLGAAGQLFATGMPVEWPAVFAGSSRRRVTLPTYAFQRRRFWET
MMAR_1762|M.marinum_M RPEVASVLTAFGQLFSTGMSVDWPAVFAGSGATRVDLPTYAFQRRRFWEV
MUL_2005|M.ulcerans_Agy99 RPEVASVLTAFGQLFSTGMSVDWPAVFAGSGATRVDLPTYAFQRRRFWEV
MAV_3108|M.avium_104 RPEVDSLLTAAARLFTAGADVRWSAAFTGLHARRVDLPTYAFARRRFWLS
TH_4621|M.thermoresistible__bu QEMPHGVRTMVGDLFAAGAAVDFAALYPSGRLVDAPLPTWTRRKLVLSRE
. : * :.. ***:. :
Mflv_0405|M.gilvum_PYR-GCK S---AGMAIDGRVGASAGSGILGSGKD-LASGD-SVYTSRLSVKTQPWLS
MAB_0939|M.abscessus_ATCC_1997 S---SGTAIEG--GGGLPSGILGRGED-LASGD-SVYISRLSVRSQPWLS
MSMEG_0408|M.smegmatis_MC2_155 A---SSIAVDG---GTAASGILGSGKD-LASGD-TIYTSRLSVKSQPWLA
Mvan_1003|M.vanbaalenii_PYR-1 T---AGIRSDG----SSGSGLLGSAQD-LASGD-IVHTSRLSVKTQPWLS
Mb2971c|M.bovis_AF2122/97 PGADGPADAAGLGLGATEHALLGAVVERPDSDE-VVLTGRLSLADQPWLA
Rv2946c|M.tuberculosis_H37Rv PGADGPADAAGLGLGATEHALLGAVVERPDSDE-VVLTGRLSLADQPWLA
MLBr_00135|M.leprae_Br4923 PGTDGTASVSGLGLGSTEHALLGAVVERPDSGG-VVLTGRLSLANQPWLA
MMAR_1762|M.marinum_M PGADGPADATGLGLGGAEHALLGAVVERPDSGG-VVLTGRLALADQPWLA
MUL_2005|M.ulcerans_Agy99 PGADGPADATGLGLGGAEHALLGAVVERPDSGG-VVLTGRLALADQPWLA
MAV_3108|M.avium_104 GDAVGSANIASLGLAEAEHPLLGAVLDRPDSGG-VVLTGRLSTAAQPWLA
TH_4621|M.thermoresistible__bu N----GEQQTRGGCTITVHPLLGTHVRLPEEPERHVWQADLGTGAQPWLA
:** . : . *. ****:
Mflv_0405|M.gilvum_PYR-GCK DHVIYGTVVVPGATYAAMALAAVGTP--AHAKDVFFYEPIILPEKSSREV
MAB_0939|M.abscessus_ATCC_1997 DHVIYGTVVVPGATYAAMALAAVGTP--ARAKDVFFYEPIILPEKSSREV
MSMEG_0408|M.smegmatis_MC2_155 DHVIYGTVVVPGATYAAMALAAVGTP--ARLKDVFFYEPIILPEKASREV
Mvan_1003|M.vanbaalenii_PYR-1 DHVIYGTVVVPGATYAAMALAAMPTP--ARVQEVFFYEPIILGDKDSREV
Mb2971c|M.bovis_AF2122/97 DHVVNGVVLFPGAGFVELVIRAGDEVGCALIEELVLAAPLVMHPGVGVQV
Rv2946c|M.tuberculosis_H37Rv DHVVNGVVLFPGAGFVELVIRAGDEVGCALIEELVLAAPLVMHPGVGVQV
MLBr_00135|M.leprae_Br4923 DHVIGGVVLFPGAGFVELVIRAGDEVGCAGVEELVLAAPLVLHPGSGVQV
MMAR_1762|M.marinum_M DHVIGGVVLFPGAGFVELAIRAGDEVGCAVVEELVLAAPLVLHPGMGVQV
MUL_2005|M.ulcerans_Agy99 DHVIGGVVLFPGAGFVELAIRAGDEVGCAVVEELVLAAPLVLHPGMGVQV
MAV_3108|M.avium_104 DHAVAGTVLFPGAGFVELALRAGDEVGCPVVEELTLSAPLSLPAGGTVQL
TH_4621|M.thermoresistible__bu DHQIHTVAALPGAAYCEMALAAAREVIDSDGVEVRDVRFEQMLLLDEQTE
** : .. .*** : :.: * . :: :
Mflv_0405|M.gilvum_PYR-GCK QLTVHPSVDGE-SKFQVHSRPYGERGAEWALNAEGVVASGVGD---SPAA
MAB_0939|M.abscessus_ATCC_1997 QLTLHPLEDGSGSKFQVHSRPYGERDVDWSLNAEGTVVTGIGDDAEPAPE
MSMEG_0408|M.smegmatis_MC2_155 QLTLHPADGGSVLSFQIHSRPYGERGADWSLNAEGTVDTAGSD---PDAA
Mvan_1003|M.vanbaalenii_PYR-1 QLMLHRTDDADGWTFEVHSRPYGDRDADWSRNASGTVAAGVGD-----AA
Mb2971c|M.bovis_AF2122/97 QVVVG-AADESGHRAVSVYSRGDQSQG-WLLNAEGMLG---------VAA
Rv2946c|M.tuberculosis_H37Rv QVVVG-AADESGHRAVSVYSRGDQSQG-WLLNAEGMLG---------VAA
MLBr_00135|M.leprae_Br4923 QVVVA-AADESSRRAVSVYSRGDQSHGGWLLNAEGLLE---------VDA
MMAR_1762|M.marinum_M QVIVG-AADDSGNRALSVYSRGDQSED-WLLNAEGMLG---------VEA
MUL_2005|M.ulcerans_Agy99 QVIVG-TADDSGNRALSVYSRGDKSED-WLLNAEGMLG---------VEA
MAV_3108|M.avium_104 QVVVADAAGQPGSRSVAVYSR--VAQSEWTLHAEGVLS---------EAA
TH_4621|M.thermoresistible__bu VSAVASAVEPGTLEFAVETAKDGEHERRATAVLGAADD----------TE
: .
Mflv_0405|M.gilvum_PYR-GCK AGDLEDPVDEAIERLNRMRPQELFETFADLELAWGPTWSGSLKSLWLG--
MAB_0939|M.abscessus_ATCC_1997 AAEPAEPVDAAIERMERMRPMELFEIFADLELAWGPTWSGSLKSLWLG--
MSMEG_0408|M.smegmatis_MC2_155 ADEQSDPVDEVIERLERMRPQDLFETFADLELAWGPTWSGSLKSLWLG--
Mvan_1003|M.vanbaalenii_PYR-1 PDAAADPVDNAIERLTRTRPQQLFDAFADNDLAWGPAWCSSLRSLWVG--
Mb2971c|M.bovis_AF2122/97 AETPMDLSVWPPEGAESVDISDGYAQLAERGYAYGPAFQG-LVAIWRR--
Rv2946c|M.tuberculosis_H37Rv AETPMDLSVWPPEGAESVDISDGYAQLAERGYAYGPAFQG-LVAIWRR--
MLBr_00135|M.leprae_Br4923 AEATVDLSLWPPEGAESVDISDAYPQLAERGYAYGPAFQG-LVAIWRR--
MMAR_1762|M.marinum_M ASSGADLSVWPPEGAESVDISDGYAQLADRGYAYGPGFQG-LVGVWRR--
MUL_2005|M.ulcerans_Agy99 ASSGADLSVWPPEGAESVDISDGYAQLADRGYAYGPGFQG-LVGVWRR--
MAV_3108|M.avium_104 PAPAAELSVWPPADAEAVDVAGGYDDLAGRGYGYGPAFRG-LRAVWRR--
TH_4621|M.thermoresistible__bu PPQAHDIDALLAEHPTRIEGDELRQWFDQRGVQFGPAFTGLTAARIPEGT
. : : :** : . .
Mflv_0405|M.gilvum_PYR-GCK EGEAIGDILVGAELAEQLGTEPMHPVLMDLCTGVAFPAFPALLAAEQGVN
MAB_0939|M.abscessus_ATCC_1997 EGEAIGDVLVGEELAEQLGTEPMHPVLMDLCTGVAFPAFPALLAAEQGVN
MSMEG_0408|M.smegmatis_MC2_155 DGEAVGDILVGAELAEQLGSEPMHPVLMDLCTGVAFPAFPALLAAEQGVN
Mvan_1003|M.vanbaalenii_PYR-1 TGEAVGDIAVGAELGEHLGREPIHPVLLDLCTGIAGAALLAAAAQTDADP
Mb2971c|M.bovis_AF2122/97 GSELFAEVVAPGEAGVAVDRMGMHPAVLDAVL----HALGLAVEKTQAST
Rv2946c|M.tuberculosis_H37Rv GSELFAEVVAPGEAGVAVDRMGMHPAVLDAVL----HALGLAVEKTQAST
MLBr_00135|M.leprae_Br4923 GSELFAEVVAP--TGVVVDGMGMHPALLDAVL----HALGLAIENTQATT
MMAR_1762|M.marinum_M DSELFAEVVAP--SGVAVDKMGMHPVVLDAVL----HALGLTAEQNPDSD
MUL_2005|M.ulcerans_Agy99 DSELFAEVVAP--SGVAVDKMGMHPVVLDAVL----HALGLTAEQNPDSD
MAV_3108|M.avium_104 GAETFAEVELPEQAGVSTGRFGIHPVLLDAAL----HALGVADKR----L
TH_4621|M.thermoresistible__bu VTSVLAEVGLPGQIRSQQAPYGIHPALLDACF----QSVAAHPDVQGAGS
. ..:: :**.::* :.
Mflv_0405|M.gilvum_PYR-GCK DLYLPLRYGQVSLQEKMPRRFYCRATWHEAPLDSETQVFDLEYLDRDGRH
MAB_0939|M.abscessus_ATCC_1997 DLFLPLRYGQVTLKEKMPRRFYCRARWHESPLDSETQVFDLDYLDRDGRH
MSMEG_0408|M.smegmatis_MC2_155 DLFLPLRYGQVTLAEKMPRRFYCRARWHRSALDSETQVFELEFVDLGGRA
Mvan_1003|M.vanbaalenii_PYR-1 ELFLPLRYGRVEVRERMPRRFYCRARWQTGGIDSETQVFDLDFLDHDGRN
Mb2971c|M.bovis_AF2122/97 ETRLPFCWRGVSLHAGGAGRVRARFASAG------ADAISVDVCDATGLP
Rv2946c|M.tuberculosis_H37Rv ETRLPFCWRGVSLHAGGAGRVRARFASAG------ADAISVDVCDATGLP
MLBr_00135|M.leprae_Br4923 EMRLPFCWRGVSLHAGGAGRVRARFTSAG------ADAIAVDIADSAGLP
MMAR_1762|M.marinum_M ETKLPFCWRGVSLHAGGAGRVRARLTMSG------PDSISVEIADAAGLP
MUL_2005|M.ulcerans_Agy99 ETKLPFCWRGVSLHAGGAGRVRARLTMSG------PDSISVEIADAAGLP
MAV_3108|M.avium_104 ETVLPFSWQGVSLHAAGASRVRVRLAPAG------AGAVSVELADASGVP
TH_4621|M.thermoresistible__bu GLLLPLGVRRLQAFGPTRGARYCYARVTDAD--GSKAEADLDVLDEHGNV
**: : :: * *
Mflv_0405|M.gilvum_PYR-GCK LGGVREFTVKRAPREALLRGLGGDAT----RLLYTLGWHEVPVP----ES
MAB_0939|M.abscessus_ATCC_1997 LGGIREFTVKRAPREALLRGLGGDAT----RLLYTLGWHEVAVPPVAGEG
MSMEG_0408|M.smegmatis_MC2_155 LGGIREFTVKRAPREALLRGLGGDAT----RLLYTLGWHEVPPP------
Mvan_1003|M.vanbaalenii_PYR-1 LGGIREFTVKRAPREALLRGLGADAT----RLIYRVGWRETSPP---VRD
Mb2971c|M.bovis_AF2122/97 VLTVRSLVTRPITAEQLRAAVTAAGG-ASDQGPLEVVWSPISVV------
Rv2946c|M.tuberculosis_H37Rv VLTVRSLVTRPITAEQLRAAVTAAGG-ASDQGPLEVVWSPISVV------
MLBr_00135|M.leprae_Br4923 VLTVRSLVTRAMTAEQLRTAVTAAGG-ALEQGPMDLVWSPIPLS------
MMAR_1762|M.marinum_M VLTVGALVTRAMSAAQLRAAVAAAGGGAPDQGPLDVIWSPIPLS------
MUL_2005|M.ulcerans_Agy99 VLTVGALVTRAMSAAQLRAAVAEAGGGAPDQGPLDVIWSPIPLS------
MAV_3108|M.avium_104 VLSVRELVTRAVSAEQLAAAVAVRSG---SGELLDVAWSVIEPR------
TH_4621|M.thermoresistible__bu LLRVQGLLMGGAAADGDDRDRVLGER------LLTIEWQRRDLP------
: : : . : *
Mflv_0405|M.gilvum_PYR-GCK GDGAAPQGTWLIGGFDELAVSVPGCIPADR----------------TNPE
MAB_0939|M.abscessus_ATCC_1997 EESAASIGTWLIAGFDELAAKVPGCIPLNRE---------------TDPE
MSMEG_0408|M.smegmatis_MC2_155 PSADDAVGTWLIAGFDELAAKVPGCVPIDRN---------------TDLQ
Mvan_1003|M.vanbaalenii_PYR-1 DGALGPSSTWLVAGLDALADDVPGSIRIGFDRIWDPDRDGRVVLDPADDE
Mb2971c|M.bovis_AF2122/97 SGGANGSAPPAPVSWADFCAGSDG--------------------------
Rv2946c|M.tuberculosis_H37Rv SGGANGSAPPAPVSWADFCAGSDG--------------------------
MLBr_00135|M.leprae_Br4923 SDGHGG-GLPSVVSWADYCAGRGN--------------------------
MMAR_1762|M.marinum_M GSGTNGSAQPAVVSWADFCAGGDGGA------------------------
MUL_2005|M.ulcerans_Agy99 GSGTNGSAQPAVVSWADFCAGGDGGA------------------------
MAV_3108|M.avium_104 NSLPDNPISEGVTVWEPAAVDGAG--------------------------
TH_4621|M.thermoresistible__bu -EADSAAGKWLLVSTSATADVSATRLSDALKQAG----------AESTSM
.
Mflv_0405|M.gilvum_PYR-GCK SLRQLLTDAHGRGLPFSGVVWRAARSDGDES--DAEVAARLEAEIAELLG
MAB_0939|M.abscessus_ATCC_1997 LLGEVLVAAKERGVPFSGVVWRAAGPGATES--TTESAARLEGEIAHLLS
MSMEG_0408|M.smegmatis_MC2_155 VLGEVLSQAHARGAGFSGVVWRCATPGRKESGSASAESARLEAEITNLLS
Mvan_1003|M.vanbaalenii_PYR-1 HWRRLFALADERRAPVAGVVLGVTGRARPEE-PSADFAARLEAQIRDVLG
Mb2971c|M.bovis_AF2122/97 ---------------DASVVVWELESAGGQASS---VVGSVYAATHTALE
Rv2946c|M.tuberculosis_H37Rv ---------------DASVVVWELESAGGQASS---VVGSVYAATHTALE
MLBr_00135|M.leprae_Br4923 ---------------DTGVVVWEFGSASAGAQAPVDSVAAVYSATHAALQ
MMAR_1762|M.marinum_M -------------AGDAGVVVWEPNPAG------EDVVGSVYAATHAALE
MUL_2005|M.ulcerans_Agy99 -------------AGDAGVVVWEPNPAG------EDVVGPVYAATHAALE
MAV_3108|M.avium_104 -------------------------------------PAAVHAATHQALG
TH_4621|M.thermoresistible__bu CWPQQADHADNVDRFRAGIADGVTGVVVLTGPKNGNPDDAAARRGSDYVR
:
Mflv_0405|M.gilvum_PYR-GCK AVHTVQ---GGEVKLPGGLWIVTERAVATESGEPVDPVQAALWGFGRTAI
MAB_0939|M.abscessus_ATCC_1997 AVHTVQNSAQNGVKLPGGLWIVTERAVATESGEPVDPVQAALWGFGRTTI
MSMEG_0408|M.smegmatis_MC2_155 AVHAAQ---GPSVKLPGGLWIVTEHGVACESGEPVDPVQAALWGFGRTTI
Mvan_1003|M.vanbaalenii_PYR-1 AVHSLS---ALGAKPAAGLWIVTERAVAAEAGEPVDPVQSALWGLGRTLI
Mb2971c|M.bovis_AF2122/97 VLQSWLG-----ADRAATLVVLTHGGVGLAGEDISDLAAAAVWGMARSAQ
Rv2946c|M.tuberculosis_H37Rv VLQSWLG-----ADRAATLVVLTHGGVGLAGEDISDLAAAAVWGMARSAQ
MLBr_00135|M.leprae_Br4923 VLQFWFG-----QDRAGTLVVLTRGAVGLVGEGISDLAAAAVWGMVRSAQ
MMAR_1762|M.marinum_M VLQSWFD-----GDRAGTLVVLTHGAVAMPGENVSDLAGAAVWGIVRSAQ
MUL_2005|M.ulcerans_Agy99 VLQSWFD-----GDRAGTLVVLTHGAVAMPGENVSDLAGAAVWGIVRSAQ
MAV_3108|M.avium_104 VLQSRLA-----GEAGGVLVVSTRGAVGLPGEDVADLAGAAVWGLVRSAQ
TH_4621|M.thermoresistible__bu HLVRITRELAEIDGDAPRLFVVTRGAQAVLPQDRPNLEQAGLRGLLRVIG
: * : *. . . : :.: *: *
Mflv_0405|M.gilvum_PYR-GCK NEEPALRCRLVDCDGSPQAVQALAALLSTP-VDEPELAVRQGKLLASRLL
MAB_0939|M.abscessus_ATCC_1997 NEEPALRAKLVDGDGSPEAVQALARLLVTP-VDEPEIAVRQGKLLASRLL
MSMEG_0408|M.smegmatis_MC2_155 NEEPALHCRLVDCDGSSEAVDLLAALLAAPGIQEPEIAVRQGKLLASRLL
Mvan_1003|M.vanbaalenii_PYR-1 AEEPGLRCLLVDLDGSEDAGPALARLLGAP-GDEPELALRQGRLLVPRLL
Mb2971c|M.bovis_AF2122/97 AENP-GRIVLIDTDAAVDASVLAG-------VGEPQLLVRGGTVHAPRLS
Rv2946c|M.tuberculosis_H37Rv AENP-GRIVLIDTDAAVDASVLAG-------VGEPQLLVRGGTVHAPRLS
MLBr_00135|M.leprae_Br4923 SEHS-GKIVLIDTDSAVDVAVLAD-------LGESQLLVRCNTVHAARLS
MMAR_1762|M.marinum_M AENP-GRIVLVDADAAVEAAELVA-------VGEPQLVVRSGAAHAARLA
MUL_2005|M.ulcerans_Agy99 AENP-GRIVLVDADAAVEAAELVA-------VGEPQLVVRSGAAHAARLA
MAV_3108|M.avium_104 AEHP-GRVVLVDTDGSLDLATVIG-------CGEPQLVVRDGVAYRARLR
TH_4621|M.thermoresistible__bu AEHPHLRTTQIDIADDADLDRVAVQLLGGG--AEDETAWRDGQWYTARLS
*.. : :* : * : * . .**
Mflv_0405|M.gilvum_PYR-GCK PWSRS----GHLTVPRG-GDYVLAPTERGAIDNLRLTDSE--VPPPAEGY
MAB_0939|M.abscessus_ATCC_1997 PWSRT----GHLTVPRG-SDYVLAPTERGAIDNLRITEKE--VPAPDEGY
MSMEG_0408|M.smegmatis_MC2_155 PWARS----GHLTLPRG-GDFVLAPTERGAIDNLRLTETD--VPEPDEGY
Mvan_1003|M.vanbaalenii_PYR-1 PWSRS----GQLAIPRG-TDYVLAPTERGVLDNLRVSETE--VTAPPEGH
Mb2971c|M.bovis_AF2122/97 PAP------ALLALPAAESAWRLAAGGGGTLEDLVIQPCPEVQAPLQAGQ
Rv2946c|M.tuberculosis_H37Rv PAP------ALLALPAAESAWRLAAGGGGTLEDLVIQPCPEVQAPLQAGQ
MLBr_00135|M.leprae_Br4923 PAP------QLLALPVGESMWRLAADGGGTLEDLVIQPCPEVQAPLQAGH
MMAR_1762|M.marinum_M PAA------PLLAVPADESAWRLAAGGGGTLEDLVIEPCPEVQAPLAAGQ
MUL_2005|M.ulcerans_Agy99 PAA------PLLAVPADESAWRLAAGGGGTLEDLVIEPCPEVQAPLAAGQ
MAV_3108|M.avium_104 PAGRR----ALLELPGPPAVWRLAAGDAGTLEDLAVQEHP--AAELAPGQ
TH_4621|M.thermoresistible__bu LSPLRPEERKQAVVDCERDGMRLEIRTPGDLETMELAAFDR--VPPGPGQ
: * * :: : : *
Mflv_0405|M.gilvum_PYR-GCK VQVRVEAAGLNFRDVLNVLG---LYPGDPGPIGGDFAGTVTQLGEGVTGL
MAB_0939|M.abscessus_ATCC_1997 VQVRVEAAGLNFRDVLNVLG---LYPGDPGPIGGDFAGIVTQLGEGVTGV
MSMEG_0408|M.smegmatis_MC2_155 VQVRVEAAGLNFRDVLNVLG---LYPGDPGPIGGDFAGTVTQLGAGVSGL
Mvan_1003|M.vanbaalenii_PYR-1 VQVRVEAAGLNFRDVLNALG---LYPGDPGPIGGELAGVVTAPGPDVDGF
Mb2971c|M.bovis_AF2122/97 VRVAVAAVGVNFRDVVAALG---MYPGQAPPLGAEGAGVVLETGPEVTDL
Rv2946c|M.tuberculosis_H37Rv VRVAVAAVGVNFRDVVAALG---MYPGQAPPLGAEGAGVVLETGPEVTDL
MLBr_00135|M.leprae_Br4923 MRVAVAAVGVNFRDVVAALG---MYPGQAPPLGAEGAGVVIEIGPEVTGV
MMAR_1762|M.marinum_M VRVAVRAVGVNFRDVVAALG---MYPGEAPPLGAEGAGVVLEVGPQVSGV
MUL_2005|M.ulcerans_Agy99 VRVAVRAVGVNFRDVVAALG---MYPGAAPPLGAEGAGVVLEVGPQVSGV
MAV_3108|M.avium_104 VRVRVAAAGVNFRDVLVALG---MYPG-AAQLGAEGAGVVTEVGAGVTDV
TH_4621|M.thermoresistible__bu IEVAVTASSINFADVLIAFGRYPTFDGRRPQLGTDFAGVVTAVGPDVTSH
:.* * * .:** **: .:* : * :* : ** * * * .
Mflv_0405|M.gilvum_PYR-GCK DVGQRVYGS-MQGAFASRFNVPGQFLAPIPDGVSAVEAATIPAAALTVRL
MAB_0939|M.abscessus_ATCC_1997 EVGQRVYGS-MQGAFGSRFNVPAQFLAPIPDGISGVEAATIPAAALTVRL
MSMEG_0408|M.smegmatis_MC2_155 EIGQRVYGS-MQGAFASRFNVPAQFLAPIPDGIGAVEAATIPAAALTVRL
Mvan_1003|M.vanbaalenii_PYR-1 DVGQRVFGF-AVGAFASRVNVPVQFLAPVPEGISAVAAATTPAAVLTAGL
Mb2971c|M.bovis_AF2122/97 AVGDAVMG--FLGGAGPLAVVDQQLVTRVPQGWSFAQAAAVPVVFLTAWY
Rv2946c|M.tuberculosis_H37Rv AVGDAVMG--FLGGAGPLAVVDQQLVTRVPQGWSFAQAAAVPVVFLTAWY
MLBr_00135|M.leprae_Br4923 AVGDAVMG--FLGGAGPLAVVHQQLITQMPQGWSLAEAAAVPVVFLTALF
MMAR_1762|M.marinum_M AVGDSVMG--FLGGAGPLSVVDQQLITRMPQGWSFAQAAAVPVVFLTALF
MUL_2005|M.ulcerans_Agy99 AVGDSVMG--FLGGAGPLSVVDQQLITRMPQGWSFAQAAAVPVVFLTALF
MAV_3108|M.avium_104 AVGDAVMG--IFGLVGSEAAVDRRLVTRVPPGWSMAQAAGIPVVFLTAYY
TH_4621|M.thermoresistible__bu RVGDRVGGLSPNGCWSTFVTCDADLAVPLPDGLTEGQAAAVSTAHATAWY
:*: * * * .. : . :* * ** ... *.
Mflv_0405|M.gilvum_PYR-GCK SFD-WAQVKSGDKVLIHAASGGVGLAAVQMAQQCGAEVYATAST-FKRAT
MAB_0939|M.abscessus_ATCC_1997 SFD-WAQLKPGDKVLIHAASGGVGLAAIQMAQQFGAEVFATAST-FKRAT
MSMEG_0408|M.smegmatis_MC2_155 AFD-WAQLKPGDKVLIHAASGGVGLAAIQMAQQSGAEVFATAST-FKRST
Mvan_1003|M.vanbaalenii_PYR-1 AFD-WAALRAGDRVLIHAASGGVGLAAVQLARQRGATVFATASG-YKRPM
Mb2971c|M.bovis_AF2122/97 GLADLAEIKAGESVLIHAGTGGVGMAAVQLARQWGVEVFVTASR-GKWDT
Rv2946c|M.tuberculosis_H37Rv GLADLAEIKAGESVLIHAGTGGVGMAAVQLARQWGVEVFVTASR-GKWDT
MLBr_00135|M.leprae_Br4923 GLADLAGIRAGESVLIHAGTGGVGMAAVQFARHWGVEIFVTASR-GKWDT
MMAR_1762|M.marinum_M GLQDLAKIQPGESVLIHAGTGGVGMAAVQLARHWGVEIFVTASR-GKWDT
MUL_2005|M.ulcerans_Agy99 GLQDLAKIQPGESVLIHAGTGGVGMAAVQLARHWGVEIFVTASR-GKWDT
MAV_3108|M.avium_104 GLSVLAGLRAGQRVLVHAATGGVGMAAVQLARHWGAEVFATASR-GKWDT
TH_4621|M.thermoresistible__bu GLHDLARLGAGEKVLIHSATGGVGLAAIAIARSVGAQIYATAGSPARRDL
.: * : .*: **:*:.:****:**: :*: *. ::.**. :
Mflv_0405|M.gilvum_PYR-GCK LRKLGVK--HVYDSRTTDFAEQILADTDGAGVDVVLNSLTSEGFIEATLR
MAB_0939|M.abscessus_ATCC_1997 LRKLGVK--YVYDSRTTDFADQILADTDGAGVDVVLNSLTSEGFIEATLR
MSMEG_0408|M.smegmatis_MC2_155 LRRLGVK--YVYDSRTTDFADQILADTNGAGVDVVLNSLTSAGFVEATLK
Mvan_1003|M.vanbaalenii_PYR-1 LRAMGVD--HVYDSRTTDFADQILADTDGAGVDVVLNSLTNDGFVAATVR
Mb2971c|M.bovis_AF2122/97 LRAMGFDDDHIGDSRTCEFEEKFLAVTEGRGVDVVLDSLAGE-FVDASLR
Rv2946c|M.tuberculosis_H37Rv LRAMGFDDDHIGDSRTCEFEEKFLAVTEGRGVDVVLDSLAGE-FVDASLR
MLBr_00135|M.leprae_Br4923 LRDMGFDDDHIGDSRTLEFEEKFLAVTDGRGVDVVLDSLAGD-FVDASLR
MMAR_1762|M.marinum_M LRAMGFDDDHIGDSRTLDFEEKFLAVTDGRGVDVVLDSLAGD-FVDASLR
MUL_2005|M.ulcerans_Agy99 LRAMGFDDDHIGDSRTLDFEEKFLAVTDGRGVDVVLDSLAGD-FVDASLR
MAV_3108|M.avium_104 LRAMGFDDAHIADSRTLDFEQKFGAAPG--GMDVVLNSLAGE-FNDASLR
TH_4621|M.thermoresistible__bu LRDMGIE--HVYDSRSTAFADEIRRDTDGYGVDVVLNSLPGA-AQRAGLE
** :*.. :: ***: * ::: . *:****:**.. * :.
Mflv_0405|M.gilvum_PYR-GCK ATAQHGRFAEIAKRDIWTVEQMAAA--RPDLAYEIVALDTVMFTEPDRIR
MAB_0939|M.abscessus_ATCC_1997 ATAKNGRFAEIAKRDIWTTEQMAQS--RPDIAYEIVALDTVMFQEPDRIR
MSMEG_0408|M.smegmatis_MC2_155 ATAQGGRFAEIAKRDIWSHEQMAEA--RPDIAYEIVALDTVMFTEPDRIR
Mvan_1003|M.vanbaalenii_PYR-1 ATARNGRFAEIAKRDIWSPEQMAAA--RPDIDYEVLALDAVMQQDPDRIQ
Mb2971c|M.bovis_AF2122/97 LLVRGGRFLEMGKTDIRDAQEIAAN--YPGVQYRAFDLSEAG---PARMQ
Rv2946c|M.tuberculosis_H37Rv LLVRGGRFLEMGKTDIRDAQEIAAN--YPGVQYRAFDLSEAG---PARMQ
MLBr_00135|M.leprae_Br4923 LLVRGGRFLEMGKTDIRDAQEIAAN--YPGVQYRAFDLSEAG---PVRMQ
MMAR_1762|M.marinum_M LLVRGGRFLEMGKTDIRDADKIAAN--YPGVWYRAFDLSEAG---PVRMQ
MUL_2005|M.ulcerans_Agy99 LLVRGGRFLEMGKTDIRDADKIAAN--YPGVWYRAFDLSEAG---PVRMQ
MAV_3108|M.avium_104 LLGPGGRFIEMGKTDLRDPDVVARA--HPGVRYRAFDLMEAG---PDRIA
TH_4621|M.thermoresistible__bu LLSFGGRFIEIGKRDIYGDTRLGLFPFRRNLAFHGVDLGLMADSHPHKIR
*** *:.* *: :. .: :. . * * ::
Mflv_0405|M.gilvum_PYR-GCK DLLTEVSAGLRDGAWTPLPAEVYPLTEARAAFRRMQQARHIGKIVVQIPN
MAB_0939|M.abscessus_ATCC_1997 VLLTEVSEGLAKGEWTPLPAEIYPLTEARTAFRRMQQARHIGKIVCQMPN
MSMEG_0408|M.smegmatis_MC2_155 DLLTEVSDGMARGEWTPLPAEIYPITEARSAFRRMQQARHIGKIVLQVPK
Mvan_1003|M.vanbaalenii_PYR-1 LLLADLADSLARGETAPLPFEAYPLAEATTAFRRMQQARHTGKIILQMPK
Mb2971c|M.bovis_AF2122/97 EMLAEVRELFDTRELHRLPVTTWDVRCAPAAFRFMSQARHIGKVVLTMPS
Rv2946c|M.tuberculosis_H37Rv EMLAEVRELFDTRELHRLPVTTWDVRCAPAAFRFMSQARHIGKVVLTMPS
MLBr_00135|M.leprae_Br4923 EMLCEVRELFDTQVLHRLPVTSWDVRCAPAAFRFMSQARHIGKVVLTMPS
MMAR_1762|M.marinum_M EMLAEVRELFDTAVLHRLPVTTWDVRCAPAAFRFMSQARHIGKVVLTMPS
MUL_2005|M.ulcerans_Agy99 EMLAEVRELFDTAVLHRLPVTTWDVRCAPAAFRFMSQARHIGKVVLTMPS
MAV_3108|M.avium_104 AMLAEVMELFAAGALTPLPVKAFDARCAADAYRFVSAARHIGKVVLTMPD
TH_4621|M.thermoresistible__bu ELLETVYRLTADGVLPMPQSTHYPLAEAATAIRVMSAAEHVGKLVLDVPH
:* : : * * * :. *.* **:: :*
Mflv_0405|M.gilvum_PYR-GCK P-----------LQP-QPDRSYLITGGLGAIG-LHTAGYLAQLGAGDIVL
MAB_0939|M.abscessus_ATCC_1997 P-----------LAP-RPDRTYLITGGLGAIG-LHTAAYLAQLGAGDIVL
MSMEG_0408|M.smegmatis_MC2_155 P-----------LQP-QQDRSYLITGGLGAIG-LHTAAYLAQLGAGDIVL
Mvan_1003|M.vanbaalenii_PYR-1 P-----------LQP-HGDRSYLITGGLGALG-LHAAAYLAQLGAGDIVL
Mb2971c|M.bovis_AF2122/97 A-----------LADRLADGTVVITGATGAVGGVLARHLVGAYGVRHLVL
Rv2946c|M.tuberculosis_H37Rv A-----------LADRLADGTVVITGATGAVGGVLARHLVGAYGVRHLVL
MLBr_00135|M.leprae_Br4923 A-----------LADGLAEGTVLITGASGAIGGVLARHMVSAYGVRHLVL
MMAR_1762|M.marinum_M A-----------LADGLADATVLITGATGAVGAVLARHMLDAYGVRHLVL
MUL_2005|M.ulcerans_Agy99 A-----------LADGLADATVLITGATGAVGAVLARHMLDGYGVRHLVL
MAV_3108|M.avium_104 G-----------PAG-LSGGTALITGATGMAGAALARHLVARHRVPHLML
TH_4621|M.thermoresistible__bu TGRADVVVPPEQASPFRSDGAYIVTGGMGGLG-LYLAGEMAAAGAGCIVL
: ::**. * * : . ::*
Mflv_0405|M.gilvum_PYR-GCK TSRRAPDAAAQQAIADIADRTKARLHVFTADVGVEADVAALLERIRAELP
MAB_0939|M.abscessus_ATCC_1997 TSRRAPDTDAQRVIGEITERSKTRIHVFTADVGAESEVAGLLERIRAELP
MSMEG_0408|M.smegmatis_MC2_155 TSRRDPDESAQRAIDEITERHKCRIHTYAADVGDEAQVADLLARIRAELP
Mvan_1003|M.vanbaalenii_PYR-1 TGRRMPDAATERAISEIAERYHCRIHTFAADVGDESAVRDLLERIRTELP
Mb2971c|M.bovis_AF2122/97 ASRRGDRAEGAAELAADLTEAGAKGQVVACDVADRAAVAGLFAQLSREYP
Rv2946c|M.tuberculosis_H37Rv ASRRGDRAEGAAELAADLTEAGAKVQVVACDVADRAAVAGLFAQLSREYP
MLBr_00135|M.leprae_Br4923 ASRRGDRAEGAVELAAELVGAGAKIQVVACDVADNDAVRGLFAQLSREFP
MMAR_1762|M.marinum_M ASRRGDRAEGAAELAAELSEAGANVQVVACDVADRDAVEAMLARLSGEYP
MUL_2005|M.ulcerans_Agy99 ASRRGDRAEGAAELAAELSEAGANVQVVACDVADRDAVEAMLARLSGEYP
MAV_3108|M.avium_104 VGRRGEAAPGMAELAAELRGAGASVSVLSCDVGDRDAVAAMLAQVPARYP
TH_4621|M.thermoresistible__bu NGRSAPSGEALRTIEQLRAAGTEVIVECGXXX---------------RGQ
.* : .
Mflv_0405|M.gilvum_PYR-GCK PLAGVAHLAGVLDDALLSQQSVERFRTALAPKAFGAVHLDRLTRVDDLDF
MAB_0939|M.abscessus_ATCC_1997 PLAGVAHLAGVLDDALLGQQSVERFRTTLAPKAFGAEYLDRLTKGDDLDF
MSMEG_0408|M.smegmatis_MC2_155 PLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHLDRLTRDDDLDF
Mvan_1003|M.vanbaalenii_PYR-1 PLAGVAHLAGVLDDALLPQQSPERFRTTLAPKAFGAWHLHRLTRDTELEF
Mb2971c|M.bovis_AF2122/97 PVRGVIHAAGVLDDAVITSLTPDRIDTVLRAKVDAAWNLHQATSDLDLSM
Rv2946c|M.tuberculosis_H37Rv PVRGVIHAAGVLDDAVITSLTPDRIDTVLRAKVDAAWNLHQATSDLDLSM
MLBr_00135|M.leprae_Br4923 PVRGVIHAAGVLDDGAITSLTPDRVDTVLRAKVDAAWNLHEATRDLDLLM
MMAR_1762|M.marinum_M PVRGVIHAAGVLDDAVISSLTPERIDTVLRAKVDAAWNLHEATLDLDLSM
MUL_2005|M.ulcerans_Agy99 PVRGVIHAAGVLDDAVISSLTPERIDTVLRAKVDAAWNLHEATLDLDLSM
MAV_3108|M.avium_104 -LRSVFHAAGVLDDAVIASLTPARIDTVLRAKVDGAWNLHELTKDLDLSA
TH_4621|M.thermoresistible__bu PVEVAVPTELRHADEHPDRRGAQLCDEFARGEQGAQRNQHRTDAGEGQRD
: * : . ..
Mflv_0405|M.gilvum_PYR-GCK FLVSSSVSSLFGSPGQSNYATANAFLDGLVAQRRAQGLPATGVNFGPWAR
MAB_0939|M.abscessus_ATCC_1997 FIVSSSVSSLFGSPGQSNYATANALLDGLIAQRRAQGLPATGINFGPWGQ
MSMEG_0408|M.smegmatis_MC2_155 FIVSSSVSSLFGSPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQ
Mvan_1003|M.vanbaalenii_PYR-1 FIVYSSGSSVLGSPGQANYATANAVLDGLVAHRKARGLPATGVNWGPWAQ
Mb2971c|M.bovis_AF2122/97 FVLCSSIAATVGSPGQGNYSAANAFLDGLAAHRQAAGLAGISLAWGLWEQ
Rv2946c|M.tuberculosis_H37Rv FALCSSIAATVGSPGQGNYSAANAFLDGLAAHRQAAGLAGISLAWGLWEQ
MLBr_00135|M.leprae_Br4923 FVLCSSIAATVGSPGQGNYSAANAFLDGLAAYRQAAGLAGTSLAWGLWEQ
MMAR_1762|M.marinum_M FVLCSSIAATVGSPGQGNYSAANSFLDGLAAHRQAAGLAGISVAWGLWEQ
MUL_2005|M.ulcerans_Agy99 FVLCSSIAATVGSPGQGNYSAANSFLDGLAAHRQAAGLAGISVAWGLWEQ
MAV_3108|M.avium_104 FVVFSSMAGIVGAPGQGNYAAANSFLDALAIHRHAHGLPALSVAWGMWEE
TH_4621|M.thermoresistible__bu AHPPGAVGHDQPDPG---------ALSDTGLDERGGQFPGVGVQIPVADP
.: . ** *. .:. : . .:
Mflv_0405|M.gilvum_PYR-GCK -GGMAS--SEAAAANISAQGLIPLEPSAALTAMAEVVANGTAQATVLKAN
MAB_0939|M.abscessus_ATCC_1997 -GGMAS--SEAATANISAQGLIPLDPSAALAALAEVVANGTGQATILKAN
MSMEG_0408|M.smegmatis_MC2_155 -GGMAS--SEAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKAN
Mvan_1003|M.vanbaalenii_PYR-1 -GGMAT--SDAARANLGAQGLIPLEPTAALNALGEIVAHGIASAVVLKAN
Mb2971c|M.bovis_AF2122/97 PGGMTAHLSSRDLARMSRSGLAPMSPAEAVELFDAALAIDHPLAVATLLD
Rv2946c|M.tuberculosis_H37Rv PGGMTAHLSSRDLARMSRSGLAPMSPAEAVELFDAALAIDHPLAVATLLD
MLBr_00135|M.leprae_Br4923 PGGMNAHLSSRDLARISRSGLAPMNPAQALELFDAALVIDHPFMVTALLD
MMAR_1762|M.marinum_M SGGMAAHLSSRDLARMSRSGLAPMNPEQAVGLLDAVLAINHPLMVATLLD
MUL_2005|M.ulcerans_Agy99 SGGMAAHLSSRDLARMSRSGLAPMNPEQAVGLLDAVLAINHPLMVATLLD
MAV_3108|M.avium_104 PSAMTAHLEERDKARMSRAGLSALSTRQALDLLDDALLGEQPLVVGTRLD
TH_4621|M.thermoresistible__bu GVGIDHRGAVRVDSGVP----------AQQGVDGEVVRHRTLSSVRSGRS
.: : : : . .
Mflv_0405|M.gilvum_PYR-GCK -WQRAAKVLGSSRPPILDLVLPSAVG--------EITGDSELLKQLQEIP
MAB_0939|M.abscessus_ATCC_1997 -WQRAAKVLGSSRPPILDLVLPSAVG--------EVTGDSELLKQLMEIP
MSMEG_0408|M.smegmatis_MC2_155 -WQRAAKVLGSARPPILDLVLPSAAG--------EATGDSELLKQLMEIP
Mvan_1003|M.vanbaalenii_PYR-1 -WQRAAKLLGATRPPILDHVLPSAVA--------AGPGDSALLKQLQDVP
Mb2971c|M.bovis_AF2122/97 RAALDARAQAGALPALFSGLARRPRRRQIDDTGDATSSKSALAQRLHGLA
Rv2946c|M.tuberculosis_H37Rv RAALDARAQAGALPALFSGLARRPRRRQIDDTGDATSSKSALAQRLHGLA
MLBr_00135|M.leprae_Br4923 RAALDAQAQAGALPPLFSRLVRRSRRRQIEDPGDATQSKLALVQRLQGLA
MMAR_1762|M.marinum_M RPALEARAQAGGLPPLFAGVVRRPRRRQIEDTGDAAQSKSALAERLNGLS
MUL_2005|M.ulcerans_Agy99 RPALEARAQAGGLPPLFAGVVRRPRRRQIEDTGDAAQSKSALAERLNGLS
MAV_3108|M.avium_104 RAALAQHRAA--LPPLLSELAGRPARRMLEHT--DMVSLTGLRARLAGMN
TH_4621|M.thermoresistible__bu SRWTAPGSRCGSGRRYGGESCRRTTG--------PAAGAAARRGRTRRRR
. . :
Mflv_0405|M.gilvum_PYR-GCK VPQRAGFVTEFLQKEVQNFLRLAQPP--AATSRFLDLGTDSLMAIELRNR
MAB_0939|M.abscessus_ATCC_1997 VPQRAGFVTEFLQREVQNFLRLAQPP--AATSRFLDLGTDSLMAIELRNR
MSMEG_0408|M.smegmatis_MC2_155 IPQRAGFVTEFLQREVQNFLRLASPP--AASSRFLDLGTDSLMAIELRNR
Mvan_1003|M.vanbaalenii_PYR-1 EAQRGSFVTEHLQRELQQILGLAQPP--AATGRFLELGMDSLMAVELRNR
Mb2971c|M.bovis_AF2122/97 ADEQLELLVGLVCLQAAAVLGRPSAEDVDPDTEFGDLGFDSLTAVELRNR
Rv2946c|M.tuberculosis_H37Rv ADEQLELLVGLVCLQAAAVLGRPSAEDVDPDTEFGDLGFDSLTAVELRNR
MLBr_00135|M.leprae_Br4923 ANRQLELLVGVVCLQAAAVLGRPSPEDIDPNTKFQDLGFDSLTAVELRNR
MMAR_1762|M.marinum_M AGERQDALVGLVCLQAAAVLGRPSPEDIDPEAGFQDLGFDSLTAVELRNR
MUL_2005|M.ulcerans_Agy99 AGERQDALVGLVCLQAAAVLGRPSPEDIDPEAGFQDLGFDSLTAVELRNR
MAV_3108|M.avium_104 PEQRQAELVELVCGNAAAVLG-HSTADVDPGDAFSDLGFDSLTAVELRNR
TH_4621|M.thermoresistible__bu RPRRPPPPPDRVRHRAGPAHGPVRR-------------------------
.: : .
Mflv_0405|M.gilvum_PYR-GCK LHSQFGGAFTINATAVFDYPTIGGLAEYLVAQLPDAETPQAAP-------
MAB_0939|M.abscessus_ATCC_1997 LHSQFGGKFTINATAVFDYPTIGGLAEYLVGQLPDADAESAEAPPAVESA
MSMEG_0408|M.smegmatis_MC2_155 LHSQFGGKFTINATAVFDYPTIGGLAEYLVGQLPDAEAPETA--------
Mvan_1003|M.vanbaalenii_PYR-1 LVGQFGSGFTITATAVFDYPTIGALAEYLAAQTPESTEEGTEMKTADPDG
Mb2971c|M.bovis_AF2122/97 LKTATG--LTLPPTVIFDHPTPTAVAEYVAQQMSGSRPTESGDPTSQVVE
Rv2946c|M.tuberculosis_H37Rv LKTATG--LTLPPTVIFDHPTPTAVAEYVAQQMSGSRPTESGDPTSQVVE
MLBr_00135|M.leprae_Br4923 LKSATG--LTLPPTVIFDHPTPTAVAEYVAQQMLKSRPAESGDETSQAVE
MMAR_1762|M.marinum_M LKSATG--LTLPPTVIFDHPTPTAIAEYVGRQIPDSQATQAEE--EKLPE
MUL_2005|M.ulcerans_Agy99 FKSATG--LTLPPTVIFDHPTPTAIAEYVGRQIPDSQATQAEE--EKLPE
MAV_3108|M.avium_104 LKIATG--LTLSPTVIFDHPTPAALAEHLGGQLTSAGPTPAAPAETAAPP
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK QSESEPGPDVTE--------------------------------------
MAB_0939|M.abscessus_ATCC_1997 EAESGAGPAAASDAVSELKE------------------------------
MSMEG_0408|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1 QPATVGHADVVLQTS-----------------------------------
Mb2971c|M.bovis_AF2122/97 PAAAEVSVHA----------------------------------------
Rv2946c|M.tuberculosis_H37Rv PAAAEVSVHA----------------------------------------
MLBr_00135|M.leprae_Br4923 PKVEEVSVHA----------------------------------------
MMAR_1762|M.marinum_M SDGEMVSVTA----------------------------------------
MUL_2005|M.ulcerans_Agy99 SDGEMVSVTA----------------------------------------
MAV_3108|M.avium_104 DRSSRIDEVVSELQTLLTQPGLSPGDRAQLVTRLQSLLSTPPQPSGHPEF
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK ---------------------------
MAB_0939|M.abscessus_ATCC_1997 ---------------------------
MSMEG_0408|M.smegmatis_MC2_155 ---------------------------
Mvan_1003|M.vanbaalenii_PYR-1 ---------------------------
Mb2971c|M.bovis_AF2122/97 ---------------------------
Rv2946c|M.tuberculosis_H37Rv ---------------------------
MLBr_00135|M.leprae_Br4923 ---------------------------
MMAR_1762|M.marinum_M ---------------------------
MUL_2005|M.ulcerans_Agy99 ---------------------------
MAV_3108|M.avium_104 PEDAFDDDIATATDSQLFAILDDEAGP
TH_4621|M.thermoresistible__bu ---------------------------