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M. tuberculosis H37Rv Rv1661 (pks7)

annotation: Probable polyketide synthase pks7
coordinates: 1875304 - 1881684
length: 2126

MNSTPEDLVKALRRSLKQNERLKRENRDLLARTTEPVAVVGMGCRYPGGVDSPETLWELVAHGRDAVSEF
PADRGWDVAGLFDPDPDAVGKSYTRCGGFLTDVAGFDAEFFGIAPSEALAMDPQQRLLLEVSWEALERAG
IDPITLRGSQTGVFAGVFHGSYGGQGRVPGDLERYGLRGSTLSVASGRVAYVLGLQGPAVSVDTACSSSL
VALHLAVQSLRLGECDLALVGGVTVMATPAMFIEFSRQRALSADGRCKAYAGAADGTAFAEGAGVLVLAR
LADARRLGHPVLALVRGSAVNQDGASNGLATPNGPAQQRVITAALASARLGVADVDVVEGHGTGTTLGDP
IEAQAILATYGQRPADRPLWLGSIKSNIGHTSAAAGVAGVIKMVQAMRHGVLPKTLHVDVPTPHVDWSAG
AVSLLTEPRPWHVPGRPRRAGVSSFGISGTNAHVILEEAPAVEPVGAAHGNDPVAVPWVLSARSAQALTN
QARRLLAWVGADENVRPLDVGWSLVNTRSLFDHRAVVVGADRTQLMEGLTGLAAGVPGADVVAGRAQTVG
KTAFVFPGQGAQWLGMGAQLCATAPVFAEHIHRCERALREHVEWSLLDVLRGAPGAPGLDRVDVVQPALW
AVMVSLAELWRSVGVVPDAVIGHSQGEIAAAYVAGALSLRDAAAVVALRSRLLVRLGGAGGMVSLACGQP
QAEKLASQWGDRLNIAAVNGVSSVVLAGETDAVTELMQRCEAEGIRARRIDVDYASHSAQVDAIREELIA
ALRGIEPRTSTVAFFSTVTGELMDTAGVNAEYWYRSIRQPVQFERAVRNAFDGGYRVFVESSPHPVLIAG
IEETLVDCDRGATGEPIVIPTLGRDDGGVGRFWLSAGQAHVAGVGVDWRAAFADLGGRRVELPTYAFARQ
RFWLDGLGAVGGDLGGVGLVGAEHGLLAAVVQRPDSGGVVLTGRISVVAAPWLADHAVGPVVLFPGTGFV
ELALRAGDEVGCSVLQELTLQAPLVLPADGVRVQVVVGGVEQSGTRNVWVYSAAGQADSSPGWTLHAQGV
LGVGSVQPAAELSVWPPVGARAMDVADGYQVLAARGYGYGPAFRGLQALWRRGAEVFADVTLPEGVPIRG
FGIHPAVLDAALHAWGIVEGEQQTMLPFSWQGVCLHASGAARVRVRLAPVGRGAVSVELADPQGLPVLSV
RQLMVRPVSAAALSRSTAGDRGLLEMIWTPVPLEGGDIGDDAVVWELPPHAGAQAGGDVLAAVYRGVHEV
LEVLQSWLASDATGLGVVVTRGAVGPVDDDVTDLAGAAVWGLVRSAQAEHPGRVVLVDTDGSVAVEDAVG
FGARSGEPQLVVRRGRVYAARLAPVAAGLTLPSASAGGWRLVAGGGGTLADVVVAPVAPVELATGQVRVA
VGAVGVNFRDVLVALGMYPGGGELGVDGAGVVVEVGPGVTGLAVGDRVMGLLGLVGSEAVVDARLVTMVP
AGWSLVEAAAVPVAFLTAFYGLSVLAEVAAGQKVLVHAGTGGVGMAAVSLARYWGAEVFVTASRAKWDTL
RAMGFDDIHISDSRSLEFEEAFLRATEGSGVDVVLNSLAGEFTDASLRLLPSGGRFIELGKTDIRDGQTV
AERHRGVRYRAFDLVEAGPDRIAAMLSEVVGLLAAGVLARLPVKTFDARCAPAAYRFVSQARHIGKVVLT
IPDGPGGQSGLAGGTVVVTGGTGMAGSAVATHLVRRHGVANLVLVSRSGEQADRAAEVAALLREGGAQVA
VVSCDVADRDALAALLAGLDPRYPLKGVFHAAGVLDDAVITGLTPDRVDTVLRAKVDGAWNLHELTEDMD
LSAFVVFSSMAGIVGTPAQGNYAAANAFLDGLVAYRRSRGLAGLSVAWGLWEQASAMTRHLGERDRARMT
QAGLAPLTTEQALGFLDTALQADRAVVVAARLDRAALAGAGAALPALFSQLAAGPTRRRIDAADTAVSMS
GLVSRLHALTPERRQRELTDLVISNAAAVLGRSSSVDINAHKAFQDLGFDSLTAVELRNRLKTATGLTLS
PTLIFDYPTPATLAEHLDSRLVTASGSDQQSLSDRVDDITRELVVLLDQPDLSANVKAHLRTRLQTMLTS
LTTEDDDIAAATESQLFAILDEELGS
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv1661pks7-100% (2126)Probable polyketide synthase pks7
M. tuberculosis H37RvRv2048cpks120.061.04% (2056) polyketide synthase pks12
M. tuberculosis H37RvRv1662pks80.061.85% (1612) polyketide synthase pks8

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1689pks70.099.91% (2126) polyketide synthase pks7
M. gilvum PYR-GCKMflv_0405-0.036.98% (2155) beta-ketoacyl synthase
M. leprae Br4923MLBr_00135-0.056.31% (2117) putative polyketide synthase
M. abscessus ATCC 19977MAB_0939-0.036.78% (2156) polyketide synthase
M. marinum MMMAR_2471pks70.070.49% (2138) polyketide synthase Pks7
M. avium 104MAV_3109-0.071.30% (2143) RifB protein
M. smegmatis MC2 155MSMEG_0408-0.037.34% (2145) type I modular polyketide synthase
M. thermoresistible (build 8)TH_4621-0.036.56% (1841) PUTATIVE mycocerosic acid synthase
M. ulcerans Agy99MUL_2266pks120.060.98% (2068) polyketide synthase, Pks12
M. vanbaalenii PYR-1Mvan_1003-0.037.29% (2156) beta-ketoacyl synthase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0405|M.gilvum_PYR-GCK          -----------------------------MGSAAHQGE-SAHRFAIVGYA
MAB_0939|M.abscessus_ATCC_1997      -----------------------------MDSAENPIE-STPRFAIIGYA
MSMEG_0408|M.smegmatis_MC2_155      -----------------------------MVSAEHPIE-PTPSFAIIGYA
Mvan_1003|M.vanbaalenii_PYR-1       ---------------MTDLQKRALQAIEVLRARVRELEGAGDGYAIVGYA
Rv1661|M.tuberculosis_H37Rv         -------MNSTPEDLVKALRRSLKQNERLKRENRDLLARTTEPVAVVGMG
Mb1689|M.bovis_AF2122/97            -------MNSTPEDLVKALRRSLKQNERLKRENRDLLARTTEPVAVVGMG
MMAR_2471|M.marinum_M               -------MDSTPDELITALRKTLKENERLKRENRDHLAQATEPVAVVGMG
MAV_3109|M.avium_104                -------MSGDTEELVRALRQSLKENERLKRENRRYLVAATEPVAVVGMG
MUL_2266|M.ulcerans_Agy99           -------MVDQLQHATEALRKALVQVERLKRTKRALLERSSEPIAIVGMS
MLBr_00135|M.leprae_Br4923          MTASVEGADQKSEKLISYLKKVVVELDETRARLREYEQRATEPVAVVGIG
TH_4621|M.thermoresistible__bu      --------------------------------VNIVGDTPVNAVAVIGMA
                                                                           .    *::* .

Mflv_0405|M.gilvum_PYR-GCK          GRFPG-ARDAESFWELLADGRDAISEVPEDR-WDVEAFFDPDPSTPGKVV
MAB_0939|M.abscessus_ATCC_1997      ARFPG-AADAEEFWDVLREGRDAISEVPADR-WDAEEFFDPEPGAPGKVV
MSMEG_0408|M.smegmatis_MC2_155      ARFPG-AASAEEYWALLRDGREAISDVPKDR-WDIEEFFDPDPSTPGKVV
Mvan_1003|M.vanbaalenii_PYR-1       LRFPG-AADADEFWDVLRGGRDAISEVPQDR-WDADEFFDADPEAAGKMV
Rv1661|M.tuberculosis_H37Rv         CRYPGGVDSPETLWELVAHGRDAVSEFPADRGWDVAGLFDPDPDAVGKSY
Mb1689|M.bovis_AF2122/97            CRYPGGVDSPETLWELVAHGRDAVSEFPADRGWDVAGLFDPDPDAVGKSY
MMAR_2471|M.marinum_M               CRYPGGIETPEGLWEMVAAGRDVVSDFPTDRGWDGASLFDPDPDAVGKSY
MAV_3109|M.avium_104                CRYPGGVDSPEALWEMVVEGRDVVSEFPADRGWDLAGLFDADPDAVGKSY
MUL_2266|M.ulcerans_Agy99           CRFPGGVDSPEGLWQMVAEGRDVMSDFPTDRGWDLADLFDPDPDTPHKSY
MLBr_00135|M.leprae_Br4923          CRFPGGVDSPDRLWDVVSECRDVVSEFPTDRGWDVDGLFDPDPDAEGKTY
TH_4621|M.thermoresistible__bu      CRLPGGIDSPQRLWEALLRGDDMVTEIPVDR-WDADDYFDPEPGVPGRTV
                                     * **    .:  *  :    : :::.* ** **    **.:* .  :  

Mflv_0405|M.gilvum_PYR-GCK          TRRAGFVDDVSGFDAPFFGMSTREVRLMDPQHRLLLETAWRAIEHSGTAP
MAB_0939|M.abscessus_ATCC_1997      TRRAGFVEDVTGFDAPFFGMSTREVRLMDPQHRLLLETAWRAVEHSGIAP
MSMEG_0408|M.smegmatis_MC2_155      TRRAGFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAP
Mvan_1003|M.vanbaalenii_PYR-1       TRRAGFVEDVAGFDAPFFGVSAREAMFMDPQHRLLLETAWRAVEHSGTAP
Rv1661|M.tuberculosis_H37Rv         TRCGGFLTDVAGFDAEFFGIAPSEALAMDPQQRLLLEVSWEALERAGIDP
Mb1689|M.bovis_AF2122/97            TRCGGFLTDVAGFDAEFFGIAPSEALAMDPQQRLLLEVSWEALERAGIDP
MMAR_2471|M.marinum_M               TRSGGFLTDVAGFDAEFFGIAPSEVMAMDPQQRLLLEVSWEALERTGIDP
MAV_3109|M.avium_104                CRCGGFLTGVGDFDAAFFGIAPSEALAMDPQQRLLLEVSWEALERAGIDP
MUL_2266|M.ulcerans_Agy99           ASTGGFVDGVADFDPGFFGIAPSEALAMDPQHRMLLELSWEALERSGIDP
MLBr_00135|M.leprae_Br4923          TRWGAFLDDAAGFDAGFFGIAPSEVLAMDPQQRLMLEVSWEALEYAGIDP
TH_4621|M.thermoresistible__bu      SRWGAFLDDVAGFDPEFFGISEREAISIDPQQRLLLETSWEAMEHAGLTP
                                       ..*: .. .**. ***::  *.  :***:*:::* :*.*:* :*  *

Mflv_0405|M.gilvum_PYR-GCK          SELANTNTGVFVGLATHDYLGMASDELSYPEIEAYMAIGTSNAAAAGRIS
MAB_0939|M.abscessus_ATCC_1997      TDLAETNSGVFVGLATHDYLGMASDELTFPEIEAYMAIGTSNAAAAGRIS
MSMEG_0408|M.smegmatis_MC2_155      TSLANSNTGVFVGLATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRIS
Mvan_1003|M.vanbaalenii_PYR-1       SALAGTRTGVFMGLSTHDYLGMLTDNLTHDAIEAYLGTGTSPAAAIGRIS
Rv1661|M.tuberculosis_H37Rv         ITLRGSQTGVFAGVFHGSYGGQG---RVPGDLERYGLRGSTLSVASGRVA
Mb1689|M.bovis_AF2122/97            ITLRGSQTGVFAGVFHGSYGGQG---RVPGDLERYGLRGSTLSVASGRVA
MMAR_2471|M.marinum_M               TTLRGSATGVFVGVFHGSYGGQG---RVPGDLERYGLRGSTLSVASGRVA
MAV_3109|M.avium_104                ATLRGSATGVFAGIFHGSYGGQG---RVPGNLERYGLRGSTLSVASGRVA
MUL_2266|M.ulcerans_Agy99           TGLRGSATGVFAGLIVQGYG------MFAEEIEGYRLTGMTSSVASGRVA
MLBr_00135|M.leprae_Br4923          LSLRGSATGVFTGIFAPSYGS-----RDTGGLQGYGLTGTAVSVASGRVS
TH_4621|M.thermoresistible__bu      ADVEGSSTGVFVGLSHDDYALLTS--DAGALEEAYGFTGSAFSMASGRIA
                                      :  : :*** *:   .*             : *   * : : * **::

Mflv_0405|M.gilvum_PYR-GCK          YRLGLQGPAVAVDTACSSSLVAIHQACQALRLGECDLALAGGANVILTPA
MAB_0939|M.abscessus_ATCC_1997      YRLGLQGPSVAVDTACSSSLVAIHQACQALQLGECDLALAGGANVLLTPA
MSMEG_0408|M.smegmatis_MC2_155      YRLGLQGPAVAVDTACSSSLVAIHQACQALRLNECDLALAGGANVLLTPA
Mvan_1003|M.vanbaalenii_PYR-1       YRLGLQGPAVAVDTACSSSLVAVHQACQALRLAECDVALAGGVNVLLSPA
Rv1661|M.tuberculosis_H37Rv         YVLGLQGPAVSVDTACSSSLVALHLAVQSLRLGECDLALVGGVTVMATPA
Mb1689|M.bovis_AF2122/97            YVLGLQGPAVSVDTACSSSLVALHLAVQSLRLGECDLALVGGVTVMATPA
MMAR_2471|M.marinum_M               YVLGLEGPAVSVDTACSSSLVALHLAVQSLRSRECDLALVGGVTVMATPA
MAV_3109|M.avium_104                YALGLEGPAVSVDTACSSSLVALHLAAQSLRSGECDLALAGGVTVMATPA
MUL_2266|M.ulcerans_Agy99           YVLGLEGPAVSVDTACSSSLVALHMAVQSLRSGECDLALAGGATVNATPT
MLBr_00135|M.leprae_Br4923          YVLGLEGPAVSVDTACSSSLVAIHWAMSSLRSGECDLALAGGVTVMGLPS
TH_4621|M.thermoresistible__bu      YRLGVHGPAVTVDTACSSSLLAVHMACRSLQVGESDLALAGGAMVMLEPR
                                    * **:.**:*:*********:*:* *  :*:  *.*:**.**. *   * 

Mflv_0405|M.gilvum_PYR-GCK          TMITFSNAHMLAPDGRCKTFDAAADGYVRGEGCGVIVIKRLEDAVRDGDR
MAB_0939|M.abscessus_ATCC_1997      TMITFSHAHMLAPDGKCKTFDAAADGYVRGEGSGVIVIKRLEDAIRDGDR
MSMEG_0408|M.smegmatis_MC2_155      TMITFSNAHMLAPDGRCKTFDAAADGYVRGEGCGVVVVKRLEDAVRDGDR
Mvan_1003|M.vanbaalenii_PYR-1       TMINFSRARMLAPDGRCKTFDATADGYVRGEGCGVVVVKRLADAIRHGDR
Rv1661|M.tuberculosis_H37Rv         MFIEFSRQRALSADGRCKAYAGAADGTAFAEGAGVLVLARLADARRLGHP
Mb1689|M.bovis_AF2122/97            MFIEFSRQRALSADGRCKAYAGAADGTAFAEGAGVLVLARLADARRLGHP
MMAR_2471|M.marinum_M               MFIEFSRQRALSADGRCKAYAGAADGTAFSEGAGALVLERLTDAQRLGHP
MAV_3109|M.avium_104                MFIEFSRQRALAADGRCKAYAGAADGTGFSEGVGVLVLERLSDARRLGHS
MUL_2266|M.ulcerans_Agy99           VFVEFSRHRGLAPDGRSKAYAGAADGVGWSEGGAMLVVERLSDAQRLGHP
MLBr_00135|M.leprae_Br4923          IFVGFSRQRGLAADGRCKAFARAADGTGWGEGAGVVVLERLSDAQRLGHT
TH_4621|M.thermoresistible__bu      KYTSASGLGMLSPTGRCHAFDVAADGFVRSEGSVMLLLKRLPDALRDNDR
                                         *    *:. *:.:::  :***   .**   ::: ** ** * .. 

Mflv_0405|M.gilvum_PYR-GCK          IRAVIRGSAINQDGASGGLTVPNGVAQQRVIGDALSRAGLAPGDVDYLEA
MAB_0939|M.abscessus_ATCC_1997      IRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKRAGVAPSEVGYLEA
MSMEG_0408|M.smegmatis_MC2_155      IRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKRAGLRPADVGYLEA
Mvan_1003|M.vanbaalenii_PYR-1       IRAVIRGSAVNQDGASGGLTVPNGAAQQRVIADALTNAGLTAADVDYLEA
Rv1661|M.tuberculosis_H37Rv         VLALVRGSAVNQDGASNGLATPNGPAQQRVITAALASARLGVADVDVVEG
Mb1689|M.bovis_AF2122/97            VLALVRGSAVNQDGASNGLATPNGPAQQRVITAALASARLGVADVDVVEG
MMAR_2471|M.marinum_M               VLAVVRGSAVNQDGASNGLATPNGPSQQRVIRAALASARLGVADVDVVEG
MAV_3109|M.avium_104                VLAVLRGSAVNQDGASNGLATPNGPSQQRVIRAALANARLGAADVDLVEG
MUL_2266|M.ulcerans_Agy99           VLALVRGSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEG
MLBr_00135|M.leprae_Br4923          VLAVVRGSAVNQDGASNGLTAPNGLAQQRVIQAALTNAGLSSADVDVVEA
TH_4621|M.thermoresistible__bu      ILAVVRGTAANQDGRTENISTPSIQAQADVYRSALAVAGVDPATVGMVEA
                                    : *::**:* **** : .::.*.  :*  *   **  * :  . *. :*.

Mflv_0405|M.gilvum_PYR-GCK          HGTGTSLGDPIEAQAAGAALGPG----REPQRPLLIGSAKTNIGHLEAAA
MAB_0939|M.abscessus_ATCC_1997      HGTGTSLGDPIEAQAAGAAYGIG----RETNDPLLIGSAKTNIGHLEAAA
MSMEG_0408|M.smegmatis_MC2_155      HGTGTSLGDPIEAQAAGEVLGAG----RAPEEPLLIGSAKTNIGHLEAAA
Mvan_1003|M.vanbaalenii_PYR-1       HGTGTPLGDPIEVQAAGAVLGVG----REPDRPLLIGSVKTNIGHLEAAS
Rv1661|M.tuberculosis_H37Rv         HGTGTTLGDPIEAQAILATYGQ-----RPADRPLWLGSIKSNIGHTSAAA
Mb1689|M.bovis_AF2122/97            HGTGTTLGDPIEAQAILATYGQ-----RPADRPLWLGSIKSNIGHTSAAA
MMAR_2471|M.marinum_M               HGTGTTLGDPIEAQAILATYGQDR--TGPGKEPLWLGSIKSNMGHTSAAA
MAV_3109|M.avium_104                HGTGTMLGDPIEAQALLATYGQD----RPVDEPLWLGSIKSNMGHTSAAA
MUL_2266|M.ulcerans_Agy99           HGTGTTLGDPIEAQALLATYGQDRGSAGAAGKALWLGSIKSNMGHTQAAA
MLBr_00135|M.leprae_Br4923          HGTATTLGDPIEAQALLATYGQG----RPADQPLWVGSIKSNMGHTQAAA
TH_4621|M.thermoresistible__bu      HGTGTPVGDPIEYNSLTQVYGKTG--------PCALTSVKTNFGHAESAA
                                    ***.* :***** ::   . *           .  : * *:*:** .:*:

Mflv_0405|M.gilvum_PYR-GCK          GIAGVIKVVLSLEHETLPKHLNFENPSPHIPWDRLPVEVVKESIPWRRGQ
MAB_0939|M.abscessus_ATCC_1997      GIAGVIKVILSLENELLPQHRNFQNPSPHIPWDRLPVEVVREARPWGR--
MSMEG_0408|M.smegmatis_MC2_155      GIAGVIKVVMALENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQR--
Mvan_1003|M.vanbaalenii_PYR-1       GIAGLLKVILSLEHQVLPKHLNFRSPSPHIPWNRLPVRIVDDPVPWTR--
Rv1661|M.tuberculosis_H37Rv         GVAGVIKMVQAMRHGVLPKTLHVDVPTPHVDWSAGAVSLLTEPRPWHVP-
Mb1689|M.bovis_AF2122/97            GVAGVIKMVQAMRHGVLPKTLHVDVPTPHVDWSAGAVSLLTEPRPWHVP-
MMAR_2471|M.marinum_M               GVAGVIKMTLAMQHGVLPQTLHVDVPTPHVDWSAGSVSLLTEARPWPET-
MAV_3109|M.avium_104                GAGGVIKMVQAIRHGVMPKTLHVDEPTPQVDWSAGAVSLLTEARPWPAR-
MUL_2266|M.ulcerans_Agy99           GVAGVIKMVQAMRHEVLPATLHVDVPSPHVDWSAGAVELLTEAQPWPAES
MLBr_00135|M.leprae_Br4923          GVAGVIKMVQAMRHHVMPATLHVDEPSPRVDWTTGAVSVLTEARDWSVE-
TH_4621|M.thermoresistible__bu      GALGMMKAILALQHGVVPQNLHFTRLPDEMAAIETNLFVPQATTLWPVR-
                                    *  *::*   ::.:  :*   :.   . .:      : :   .  *    

Mflv_0405|M.gilvum_PYR-GCK          RGGRPRIAGVSSFGFAGTNAHVILEEAPLAAEPAQES---VDDGRFTLLP
MAB_0939|M.abscessus_ATCC_1997      -NGRPRIAGVSSFGFAGTNAHVILEEAPVVSRDAVEPPAPAGGRKFSILP
MSMEG_0408|M.smegmatis_MC2_155      -NGKPRIAGVSSFGFAGTNAHVILEEAPAVGTPATTEP-VEDPRRYSVLP
Mvan_1003|M.vanbaalenii_PYR-1       -SGRSRVAGISSFGFSGTNAHVLVEEAPRADRAGAAPQ-PAAPGGFGMLP
Rv1661|M.tuberculosis_H37Rv         --GRPRRAGVSSFGISGTNAHVILEEAPAVEPVGAAHGNDP---VAVPWV
Mb1689|M.bovis_AF2122/97            --GRPRRAGVSSFGISGTNAHVILEEAPAVEPVGAAHGNDP---VAVPWV
MMAR_2471|M.marinum_M               --GRARRAGISSFGISGTNAHVILEQAPAAEEVAAQHRTD-----LTPWI
MAV_3109|M.avium_104                --DRPRRAGVSSFGISGTNAHVIVEQY---EPETVAPQGGD---VVVPWV
MUL_2266|M.ulcerans_Agy99           AGDRVRRAGVSSFGISGTNAHVIVEAAPRVEVGGSS-GGAV---PVVPWV
MLBr_00135|M.leprae_Br4923          --GRPRRAGVSSFGISGTNAHVILEEAPTPVEASYSTADQQRL-SVVPWV
TH_4621|M.thermoresistible__bu      -EGCPRRAAVSSYGMSGTNVHAVLEQAPEPVQRPEESADTD-AAGPLVFA
                                      .  * *.:**:*::***.*.::*                         

Mflv_0405|M.gilvum_PYR-GCK          LSARTPAALMAVADRYRDWLVAN-PDATLADLCFTAGTARSHLEHRAALV
MAB_0939|M.abscessus_ATCC_1997      LSARTPAALAQLADKYRAWLNAH-PEAALADLCFTAGVGRAHLEHRAALV
MSMEG_0408|M.smegmatis_MC2_155      LSARTPEALVRLAGEYRDWLRAH-PQARLADVSHTAGTARAHLEQRAALV
Mvan_1003|M.vanbaalenii_PYR-1       LSARTPDALAATAHRLRTWLAAN-PDASWPDLCFTAAVGRSHLRHRAALV
Rv1661|M.tuberculosis_H37Rv         LSARSAQALTNQARRLLAWVGAD-ENVRPLDVGWSLVNTRSLFDHRAVVV
Mb1689|M.bovis_AF2122/97            LSARSAQALTNQARRLLAWVGAD-ENVRPLDVGWSLVNTRSLFDHRAVVV
MMAR_2471|M.marinum_M               LAARSAPALVNQARRLAQWVSDR-PDLDVADVGWSLATTRSVFEHRAVVV
MAV_3109|M.avium_104                LSARSAEALTNQAARLLARVKAD-PGVRVLDVGWSLVSTRSRFEHRAVIV
MUL_2266|M.ulcerans_Agy99           VSAKSGSALGAQAARLAAHVRSH-DELDVADVGWSLAG-RSTFEHRAVVL
MLBr_00135|M.leprae_Br4923          VSGRSTAALMAQASRLAFYVQAD-PEVDPVDVGCALAA-RSVFEHRAVVV
TH_4621|M.thermoresistible__bu      LSSTSAEELRRTAGRLAEWVEAHTDEVVPADLAYTLARRRAHRPVRTTVI
                                    ::. :   *   * .    :          *:  :    *:    *:.::

Mflv_0405|M.gilvum_PYR-GCK          VNTREAALDLLGALADDRPA-PGLVRGESHDTPKTAWLFTGQGSQYPGMS
MAB_0939|M.abscessus_ATCC_1997      VNTREAAVELLSAVADDRPA-PGLGRGESHDTPKTAWLFTGQGSQYPGMA
MSMEG_0408|M.smegmatis_MC2_155      VNSRESAIELLGALADDRPA-PGLVRGESHEAPKTAWLFTGQGSQYPGMA
Mvan_1003|M.vanbaalenii_PYR-1       VDSRSSVEELLGALAEDRPG-PGLARGECGDPPKTAWLFTGQGSQYPGMG
Rv1661|M.tuberculosis_H37Rv         GADRTQLMEGLTGLAAGVPG-ADVVAGRAQTVGKTAFVFPGQGAQWLGMG
Mb1689|M.bovis_AF2122/97            GADRTQLMEGLTGLAAGVPG-ADVVAGRAQTVGKTAFVFPGQGAQWLGMG
MMAR_2471|M.marinum_M               GADRTQLIQGLAGFVDGEPR-AGVVVGRARPVGKTVFVFPGQGSQWVGMG
MAV_3109|M.avium_104                GADGAQLLRRLADLAGGQPG-AGVVTGRAQPVGKTVFVFPGQGSQWPGMG
MUL_2266|M.ulcerans_Agy99           GADRDGLLAGLDELAGDEFGGASVIRGVAGAAGKTVFVFPGQGSQWIGMG
MLBr_00135|M.leprae_Br4923          GESREQLIAGLAGLAVGESG-AGVAIGQAAPLGKTVVVFPGQGAQRIGMG
TH_4621|M.thermoresistible__bu      ADGVEALTAGLREVADGDAP---YQPAVGMDDKAPVWVFSGQGSQWAGMG
                                              *  .. .         .       .. :*.***:*  **.

Mflv_0405|M.gilvum_PYR-GCK          RELFDTEPLFAETLRECAAAVDGMLEKPLLDVIFDTDGVLDTDSNETLRH
MAB_0939|M.abscessus_ATCC_1997      RELFETEPVFADTLNRCAAAVADVLEKPLLDVIFDVD---GPEAEETLRQ
MSMEG_0408|M.smegmatis_MC2_155      RELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDAD-ELDGDTESPLRH
Mvan_1003|M.vanbaalenii_PYR-1       RELFDTEPVYREVMTRCAEAVADVLERPLLDVVFDAD------GGEALRH
Rv1661|M.tuberculosis_H37Rv         AQLCATAPVFAEHIHRCERALREHVEWSLLDVLRGAP------GAPGLDR
Mb1689|M.bovis_AF2122/97            AQLCATAPVFAEHIHRCERALREHVEWSLLDVLRGAP------GAPGLDR
MMAR_2471|M.marinum_M               VDLLDTSTVFADQMHRCEKALAEYVSWSLLDVVRAVP------GAPGLNR
MAV_3109|M.avium_104                AQLLDRSTVFAEHMHRCARALAEHVDWSLIDVIRGAP------GAPGLDR
MUL_2266|M.ulcerans_Agy99           IELLDTAPVFARHIESCGQAFAEFVDWSLLDVLRGAA------GAPGLDR
MLBr_00135|M.leprae_Br4923          RELCSQLPVFAEEFDAVTGELDRHMRLPLRDVVWGAD------AG-LLDS
TH_4621|M.thermoresistible__bu      AELLATEQVFAAKIAEIEPLVARESGFSVTEAMTASET---------VTG
                                     :*     ::   .      .      .: :.:              :  

Mflv_0405|M.gilvum_PYR-GCK          TSYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVGQYAAACVAGVLSLRD
MAB_0939|M.abscessus_ATCC_1997      TSYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVGQYSAACVAEVFSLED
MSMEG_0408|M.smegmatis_MC2_155      TTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVED
Mvan_1003|M.vanbaalenii_PYR-1       TSYAQPALYAVEMGLARLWQSWGIEPDVVLGHSVGQYAAACVAGVMGLED
Rv1661|M.tuberculosis_H37Rv         VDVVQPALWAVMVSLAELWRSVGVVPDAVIGHSQGEIAAAYVAGALSLRD
Mb1689|M.bovis_AF2122/97            VDVVQPALWAVMVSLAELWRSVGVVPDAVIGHSQGEIAAAYVAGALSLWD
MMAR_2471|M.marinum_M               VDVVQPVLWAIMVSLAELWRSAGVLPDAVIGHSQGEIAAAYVAGALSLED
MAV_3109|M.avium_104                VDVVQPALWAVMVSLAELWRSVGVVPDAVIGHSQGEIAAACVAGALSLHD
MUL_2266|M.ulcerans_Agy99           IDVVQPVLFAVMVSLAELWKSVGVRPDAVIGHSQGEIAAAYVAGALSLRD
MLBr_00135|M.leprae_Br4923          TEFAQPALFAVEVALFAVLQHWGLQPDFVMGHSIGELAAAYVAGVLAPAD
TH_4621|M.thermoresistible__bu      IDRVQPTLFAIQVALAATMQSYGVRPGAVIGHSLGEVAAAVVAGALSLED
                                       .**.*:*: :.*    :  *. *. *:*** *: :** ** .:   *

Mflv_0405|M.gilvum_PYR-GCK          GARLMAERGRLFGSLPSGGRMAAVFAAAERVEALTDEY--PALSVAAYNG
MAB_0939|M.abscessus_ATCC_1997      GARLIAERGRLFSSLPAGGRMAAVFTDAERAERLTDEF--PSLSVAAYNG
MSMEG_0408|M.smegmatis_MC2_155      GARLIAERGRLFGSLPAGGRMAAVFTAPERAERLTDEY--PSLSVAAYNG
Mvan_1003|M.vanbaalenii_PYR-1       GAVLLAERGRLFGSLPEGGRMAAVFAPADRVESCTVDS--PLLSVAAYNG
Rv1661|M.tuberculosis_H37Rv         AAAVVALRSRLLVRLGGAGGMVSLACGQPQAEKLASQWG-DRLNIAAVNG
Mb1689|M.bovis_AF2122/97            AAAVVALRSRLLVRLGGAGGMVSLACGQPQAEKLASQWG-DRLNIAAVNG
MMAR_2471|M.marinum_M               AARVVARRSQLLVQLSGAGGMVSLACGLERARQLVASWS-DRLSIAAVNG
MAV_3109|M.avium_104                AARVVALRSRLLVRLSGRGGMVSLACGRSRAEQLIAPWG-ERLNIATVNG
MUL_2266|M.ulcerans_Agy99           AAKVVTLRSKLLVGLAGPGGMVSVACGEQQARELLEPFG-DRVSIAAING
MLBr_00135|M.leprae_Br4923          AAMLVVARGRLMQSMPAGGTMWAVAASE---DEVVSLLG-EGVGIAAINA
TH_4621|M.thermoresistible__bu      GVKVICRRSRLCLRLAGAGAMAAIELPAQAVREFLAARGVDDVVLSVIAS
                                    .. ::  *.:*   :   * * ::                  : ::.  .

Mflv_0405|M.gilvum_PYR-GCK          -ANTVLSGPATDLERAVAGLVADGVRCDWLETSHAFHSALLDPILDDFES
MAB_0939|M.abscessus_ATCC_1997      -ANTVLSGPAQDLEKAIAALVADGVRCDFLETSHAFHSALLDPILDEFEA
MSMEG_0408|M.smegmatis_MC2_155      -ANTVLSGPAKDLESAVATLVADGVRCDWLDTSHAFHSALLDPILDDFES
Mvan_1003|M.vanbaalenii_PYR-1       -DNTVLSGPAGDLERAVAGFSAAGVRCDWLDTSHAFHSALLDPVLEEFES
Rv1661|M.tuberculosis_H37Rv         VSSVVLAGETDAVTELMQRCEAEGIRARRIDVDYASHSAQVDAIREELIA
Mb1689|M.bovis_AF2122/97            VSSVVLAGETDAVTELMQRCEAEGIRARRIDVDYASHSAQVDAIREELIA
MMAR_2471|M.marinum_M               VSAIVVSGEVDALDALIGRCEADDIRARRIDVDYASHSAQVEAIRAELAE
MAV_3109|M.avium_104                ISAVVVSGEVDALTELLDRCAADDIRARRIDVDYASHSVQVEEIRDSLAE
MUL_2266|M.ulcerans_Agy99           PSAVVVSGEVAALEELIAQCADRELRTRRIDVDYASHSVEVEAIEGQLTE
MLBr_00135|M.leprae_Br4923          PESVVISGPQAAVSAIADKFAAQGRRVHQLAVSHAFHSPLMEPMLEEFVR
TH_4621|M.thermoresistible__bu      PESTVIGGATDTVRELVAAWEAQGVMAREVAVDVASHSPQVDPILDELEE
                                        *:.*    :                : .. * **  :: :  .:  

Mflv_0405|M.gilvum_PYR-GCK          YARGITFTAPQRILIDNRTGAALGRSVTLDAAYWRRHARQPVEFAKSVHT
MAB_0939|M.abscessus_ATCC_1997      YANQFNYKTPQRILIDNRTGTALGRSVKLDGAYWRRHARQPVEFAKSVRT
MSMEG_0408|M.smegmatis_MC2_155      FAQKLEYREPQRILIDNRTGSALGRSTRLDGAYWRRHARQPVEFAKSVRT
Mvan_1003|M.vanbaalenii_PYR-1       CADRFEFGTPQRTLVCNRSGEVLSRHARLDGQYWRRHARQPVRFAESVRT
Rv1661|M.tuberculosis_H37Rv         ALRGIEPRTSTVAFFSTVTG-ELMDTAGVNAEYWYRSIRQPVQFERAVRN
Mb1689|M.bovis_AF2122/97            ALRGIEPRTSTVAFFSTVTG-ELMDTAGVNAEYWYRSIRQPVQFERAVRN
MMAR_2471|M.marinum_M               ALDGIAPQSTSTAFISTVTG-EFTDTAGLDADYWHRSIRQTVQFERAIRT
MAV_3109|M.avium_104                ALRGIAPRSSAVAFFSTVTG-ELMDTAALDGDYWFRSIRQTVQFERAVRG
MUL_2266|M.ulcerans_Agy99           VLAGIEPLSSRTAFFSSVTG-SRLDTAELDAEYWYRNIRQTVQFDQAVRS
MLBr_00135|M.leprae_Br4923          VAAQVEVRKPQIGLVSNVTG-ELAGPDFGSPQYWGEHVSRAVRFVDSARH
TH_4621|M.thermoresistible__bu      ILADLQPMTPTVPYYS-ATSYDPREKPVCDADYWVDNLRHEVRFAAAVQA
                                        .    .        :.         .  **     : *.*  : : 

Mflv_0405|M.gilvum_PYR-GCK          LADMNCKLLVEIGPRPVLTAAALSAWPDP----ATSPRVIASLRRTTADQ
MAB_0939|M.abscessus_ATCC_1997      LADMNCKVLLEIGPQPVLTAAALRAWPDP----ATAPRAIASLRRNTADH
MSMEG_0408|M.smegmatis_MC2_155      LADMNCRVLLEIGPRPVLTATALAAWPDP----ATTPQVLASLRPTTADH
Mvan_1003|M.vanbaalenii_PYR-1       LADLGCRLLMEIGPQPVLTAAAMRTWPGT----VTAPRVAASMRRKGSDR
Rv1661|M.tuberculosis_H37Rv         AFDGGYRVFVESSPHPVLIAGIEETLVDCDRGATGEPIVIPTLGRDDGGV
Mb1689|M.bovis_AF2122/97            AFDGGYRVFVESSPHPVLIAGIEETLVDCDRGATGEPIVIPTLGRDDGGV
MMAR_2471|M.marinum_M               AFNSGCQVFIESSPHPVLMAGIEETLAGQQD--SGEAIVIPSLGRDDGGL
MAV_3109|M.avium_104                AAEAGYRAFIECSPHPVLTAAIEETMP-----DGGQGCVIPSLGRDDGGP
MUL_2266|M.ulcerans_Agy99           ACGHGYRTFIESSPHPALIAGIEDTYRNCAADSGADPIVVPTLGREDGGL
MLBr_00135|M.leprae_Br4923          LQTLGATHFIESGPSSGLMGAIEQSLAP------AEAVVVSMMGKDRPEL
TH_4621|M.thermoresistible__bu      ALEDGFRVFGELSPHPLLTRAVEQTARGLD----MPVAALPAMRREQEMP
                                        .   : * .* . *      :             . . :       

Mflv_0405|M.gilvum_PYR-GCK          RQITEAVADAYVLGHLPRFAAFRRD-GARVLDLPTYPFEHRQYWFSDSRE
MAB_0939|M.abscessus_ATCC_1997      RQITEAAADAYVLGHLPDFGAFQHA-PARKLDLPTYPFERRQYWFSDKRD
MSMEG_0408|M.smegmatis_MC2_155      RQITEAVAAAYAAGHLPDFRAFRQP-DARKLDLPTYPFEHRQFWFSDNRA
Mvan_1003|M.vanbaalenii_PYR-1       RQITEALAQAYVAGHRPETAARQHG-RGRLLDLPTYPFQHRAYWFP----
Rv1661|M.tuberculosis_H37Rv         GRFWLSAGQAHVAGVGVDWRAAFADLGGRRVELPTYAFARQRFWLDGLGA
Mb1689|M.bovis_AF2122/97            GRFWLSAGQAHVAGVGVDWRAAFADLGGRRVELPTYAFARQRFWLDGLGA
MMAR_2471|M.marinum_M               QRFWLSVAQAHVAGVRVDWASIIG--AGRRVALPTYGFQHRRFWLGQLDA
MAV_3109|M.avium_104                DRFWLSAGQAFVSGVVVDWCAMLDGLGGRRVDLPTYGFVRQHFWLPGGST
MUL_2266|M.ulcerans_Agy99           QRFLASAAAAFVAGVNVDWRGPLD--GAGLVELPTYAFEKRRFWLSG-EG
MLBr_00135|M.leprae_Br4923          ASVLGAAGQLFATGMPVEWPAVFAGSSRRRVTLPTYAFQRRRFWETPGTD
TH_4621|M.thermoresistible__bu      HGVRTMVGDLFAAGAAVDFAALYPS--GRLVDAPLPTWTRRKLVLSR-EN
                                      .    .  .. *      .         :  *   : ::         

Mflv_0405|M.gilvum_PYR-GCK          ---PVAAAPQR---GARTETVRLLEDGRIEELAALLGGTVDDPFTFDVLN
MAB_0939|M.abscessus_ATCC_1997      GDNRDAGNRQQNNGGPRTEAVRLLEDGKIEELANLLGGVDGDQQTLNVLT
MSMEG_0408|M.smegmatis_MC2_155      IDRDTQTASAGSVTPHRTQAVRLLEDGQIEELAALIDGETVDEQTLRVLN
Mvan_1003|M.vanbaalenii_PYR-1       ----QGQARTAPTDPVHTETVRFLDEERIDELAALLDGPTGSAQTVDVLS
Rv1661|M.tuberculosis_H37Rv         VGGDLGGVGLVGAEHGLLAAVVQRPDSGGVVLTGRISVVAAPWLADHAVG
Mb1689|M.bovis_AF2122/97            VGGDLGGVGLVGAEHGLLAAVVQRPDSGGVVLTGRISVVAAPWLADHAVG
MMAR_2471|M.marinum_M               GRTDVGGLGQAGAAHGLLGAVVERPDSGGVVLTGQLSVALQPWLAGHAVA
MAV_3109|M.avium_104                GSSDVAALGLRGAEHGLLGAVLPRPDSGGVVLTGRLSTSAQAWLADHAVG
MUL_2266|M.ulcerans_Agy99           VSVDASGLGLSAGGHALLGAVVELPESGGVVLTGRLALGAHGWLADHAVS
MLBr_00135|M.leprae_Br4923          GTASVSGLGLGSTEHALLGAVVERPDSGGVVLTGRLSLANQPWLADHVIG
TH_4621|M.thermoresistible__bu      GEQQTRGGCTITVHPLLGTHVRLPEEPERHVWQADLGTGAQPWLADHQIH
                                                        *    :         :        :   : 

Mflv_0405|M.gilvum_PYR-GCK          RLAAQHNQQRSTESIADDRYQIRWETAAEPPVGADAADGITWLLVGDDTD
MAB_0939|M.abscessus_ATCC_1997      KLAAQHNLQRTTQTIADDRYQFRWEKSPTPLSGSQAAGGVTWLLVADAAG
MSMEG_0408|M.smegmatis_MC2_155      KLAARHNQQRSTHVDPDARYEIRWDAIASAAASTGAAA--DWILVGDDTA
Mvan_1003|M.vanbaalenii_PYR-1       KLAARHRQQRGAQSIADARYQIRWEKSEAPGAARPTTEATTWLLVTHDSR
Rv1661|M.tuberculosis_H37Rv         PVVLFPG-------TGFVELALRAGDEVGCSVLQELTLQAPLVLPADG-V
Mb1689|M.bovis_AF2122/97            PVVLFPG-------TGFVELALRAGDEVGCSVLQELTLQAPLVLPADG-V
MMAR_2471|M.marinum_M               GTVLFPG-------AGFVELAIRAGDEVGCAAVEELTLSAPLVLPTVGGV
MAV_3109|M.avium_104                DTVLFPG-------AGFVELAIRAGDEVGCGVIDELTLSAPLPLPASGGV
MUL_2266|M.ulcerans_Agy99           GVVVFPG-------TGFVELAIRAVDEVGCSVVNELTLRTPLVLPASGSV
MLBr_00135|M.leprae_Br4923          GVVLFPG-------AGFVELVIRAGDEVGCAGVEELVLAAPLVLHPGSGV
TH_4621|M.thermoresistible__bu      TVAALPG-------AAYCEMALAAAREVIDSDGVEVRDVRFEQMLLLDEQ
                                      .               .  :                     :      

Mflv_0405|M.gilvum_PYR-GCK          ATRPLVDVLAARGHRYRILGLPKSGAEEHELADTLRDAAADATDLRIVHV
MAB_0939|M.abscessus_ATCC_1997      AAQPLLDVLTARGQQHRVLALPVSDADEAELVEALRSAADEDSALRIVHV
MSMEG_0408|M.smegmatis_MC2_155      AVLEFADALTAGGHRHQIVALPGSDADEAQLVDTLRAASAG--ELYVVHI
Mvan_1003|M.vanbaalenii_PYR-1       AAQPIAEVLERRGHPYHIVGLPGSDADAAPAEEALRATVSQ-PRPHILYL
Rv1661|M.tuberculosis_H37Rv         RVQVVVGGVEQSGTRNVWVYSAAG---QADSSPGWTLHAQG-----VLGV
Mb1689|M.bovis_AF2122/97            RVQVVVGGVEQSGTRNVWVYSAAG---QADSSPGWTLHAQG-----VLGV
MMAR_2471|M.marinum_M               QLQVVVGPADQSDHRTVEVYSRGD---QSLS--EWSLHAEG-----VLAP
MAV_3109|M.avium_104                RLQLVVGAPDEAGRRPLSVYSAAA---HQDS--EWMLHAEG-----VLRT
MUL_2266|M.ulcerans_Agy99           AVQVVVGAAADSAERSVSIYSRTDTDTDTDAGSVWVCHAEG-----TLGA
MLBr_00135|M.leprae_Br4923          QVQVVVAAADESSRRAVSVYSRGD-----QSHGGWLLNAEG-----LLEV
TH_4621|M.thermoresistible__bu      TEVSAVASAVEPGTLEFAVETAKDGEHERRATAVLGAADDT---------
                                                      :                               

Mflv_0405|M.gilvum_PYR-GCK          AALDAAESDTSMKSLLRMQHRVLGGTRRLFG--AAVAAQLRSPMWLVTRG
MAB_0939|M.abscessus_ATCC_1997      AALAGQGS-SSAQSLLRIQHQVLGGTRRLFR--AAAAAELRAPIWIVTRG
MSMEG_0408|M.smegmatis_MC2_155      AAGDGAAA--PMRDLLRVQHRTLGGLRRLFR--AANDAELRSPIWLVTRD
Mvan_1003|M.vanbaalenii_PYR-1       AALEEPGG-SAAETLGWMQHRVLAAARRLFQ--LAATAGARAPIWLITAG
Rv1661|M.tuberculosis_H37Rv         GSVQPAAELSVWPPVGARAMDVADGYQVLAARGYGYGPAFRGLQALWRRG
Mb1689|M.bovis_AF2122/97            GSVQPAAELSVWPPVGARAMDVADGYQVLAARGYGYGPAFRGLQALWRRG
MMAR_2471|M.marinum_M               AAVASVGQLTAWPPEGATALDLGGVYDRLAARGYEYGPAFRGLQAVWESG
MAV_3109|M.avium_104                GTVTPAGDLSIWPPIGATAVDVTGGYARLAQRGYEYGRAFRGLRAMWQRG
MUL_2266|M.ulcerans_Agy99           DSAQPAADLSAWPPAGAIAVDVADGYERLDARGYGYGPAFRGLTAMWARG
MLBr_00135|M.leprae_Br4923          DAAEATVDLSLWPPEGAESVDISDAYPQLAERGYAYGPAFQGLVAIWRRG
TH_4621|M.thermoresistible__bu      -EPPQAHDIDALLAEHPTRIEGDELRQWFDQRGVQFGPAFTGLTAARIPE
                                                                :            .        

Mflv_0405|M.gilvum_PYR-GCK          ---AQHVTDTDVVAPDQTCLWGFGRAASLEHPQIWGGLADLG----GGTS
MAB_0939|M.abscessus_ATCC_1997      ---AQHVIEGDTVAPEQSALWGFGRAAALELPQVWGGLADLS----DAGT
MSMEG_0408|M.smegmatis_MC2_155      ---GQRVTDTDTVVPEQSCLWGFGRAAALELPHIWGGLADLS----GADT
Mvan_1003|M.vanbaalenii_PYR-1       ---AQRITGDETVEPAQTSLWGFGRAAALEQPELWGGLADVT----TGDA
Rv1661|M.tuberculosis_H37Rv         ---AEVFADVTLPE--GVPIRGFGIHPAVLDAALHAWGIVEG----EQQT
Mb1689|M.bovis_AF2122/97            ---AEVFADVTLPE--GVPIRGFGIHPAVLDAALHAWGIVEG----EQQT
MMAR_2471|M.marinum_M               ---DEIFAEVALPEDAGAQIGGFGIHPALLDAALHALVLTAE----QNQT
MAV_3109|M.avium_104                ---DEIFAEVALPDD-AAAGDDFGVHPVLLDAALHALGVAGE----KDQT
MUL_2266|M.ulcerans_Agy99           ---EELFAEARLPEA-AGSTSGFGVHPALLDAALHTAVIANP----DADL
MLBr_00135|M.leprae_Br4923          ---SELFAEVVAPTG--VVVDGMGMHPALLDAVLHALGLAIENTQATTEM
TH_4621|M.thermoresistible__bu      GTVTSVLAEVGLPGQIRSQQAPYGIHPALLDACFQSVAAHPDVQGAGSGL
                                        . .                *  . :  . .                

Mflv_0405|M.gilvum_PYR-GCK          DEWSRLLNRIAA------------THDPAVMEDQVAVRGSTSYVPRLVHR
MAB_0939|M.abscessus_ATCC_1997      DEWAQFIGRVSV------------SGEASTREDQLALRGQAVHVPRLVRR
MSMEG_0408|M.smegmatis_MC2_155      -EWPRLIARITS------------PRDG---EDQIALRGDAVYAPRLVRR
Mvan_1003|M.vanbaalenii_PYR-1       EEWSALIDHIVA------------APTS---EDQIAVRGREIHVARLTRC
Rv1661|M.tuberculosis_H37Rv         MLPFSWQGVCLH------------ASGAARVRVRLAPVGRGAVSVELADP
Mb1689|M.bovis_AF2122/97            MLPFSWQGVCLH------------ASGAARVRVRLAPVGRGAVPVELADP
MMAR_2471|M.marinum_M               VLPFAWQGVSLH------------AAGASRCRVRIAQSRSGSVAMELADS
MAV_3109|M.avium_104                VLPFSWQGVALH------------ASGASRARVRIAPAGAGAVSVELADG
MUL_2266|M.ulcerans_Agy99           VLPFSWQGVSLH------------AAGAASVRVRIAPVGPSSVSVELADD
MLBr_00135|M.leprae_Br4923          RLPFCWRGVSLH------------AGGAGRVRARFTSAGADAIAVDIADS
TH_4621|M.thermoresistible__bu      LLPLGVRRLQAFGPTRGARYCYARVTDADGSKAEADLDVLDEHGNVLLRV
                                                                   . .            :   

Mflv_0405|M.gilvum_PYR-GCK          DTLPSGKPLHLRADATYLVTGGLGSLGLEIAGYLAANGAGHLVLTSRRTP
MAB_0939|M.abscessus_ATCC_1997      EELPSGKPLEVRSDATYLVTGGLGSIGLEIAGYLAGRGAKHLVLTSRREP
MSMEG_0408|M.smegmatis_MC2_155      TGEPSDTPLPVREDRTYLVTGGLGAIGLEVAGYLASHGAGHVVLTSRREP
Mvan_1003|M.vanbaalenii_PYR-1       AEKANAAALELRREATYLVTGGLGALGLEVAEFLASHGAGHLVLTGRRSA
Rv1661|M.tuberculosis_H37Rv         QGLP---VLSVRQLMVRPVSAAALSR--STAGD---RGLLEMIWTPVPLE
Mb1689|M.bovis_AF2122/97            QGLP---VLSVRQLMVRPVSAAALSR--STAGD---RGLLEMIWTPVPLE
MMAR_2471|M.marinum_M               AGLP---VLTVRDLAFRPVSDQTSSA--GTAGG---GGLLEVVWSPLARP
MAV_3109|M.avium_104                AGLP---VLSVRSVTMRPVSPGQLSAAMGTAQP---SGLLDVIWSPIALG
MUL_2266|M.ulcerans_Agy99           LGLP---VLSVKAMVARPVSEQQMRAVVSASGP---DRLFEVVWTPMTVA
MLBr_00135|M.leprae_Br4923          AGLP---VLTVRSLVTRAMTAEQLRTAVTAAGGALEQGPMDLVWSPIPLS
TH_4621|M.thermoresistible__bu      QGLLMGGAAADGDDRDRVLGERLLTIEWQRRDLPEADSAAGKWLLVSTSA
                                                      :                               

Mflv_0405|M.gilvum_PYR-GCK          DEAAASRIEALRERHGCEVRVVTADVADAHAVARLLATVQAEMPPLAGIV
MAB_0939|M.abscessus_ATCC_1997      GEAARQRIDALAA-QGCEVRAVTADVADGHDVARLLAGIQAELPPLAGIV
MSMEG_0408|M.smegmatis_MC2_155      GDDARRRLDGLREQYACDVRVITADVADAHDVARLMTTVAAELPPLAGIV
Mvan_1003|M.vanbaalenii_PYR-1       SDTVRQRIDAMRERFDCQVLVATADVADRDDVARLFSTMRSELPPLAGIV
Rv1661|M.tuberculosis_H37Rv         GGDIGDD-------------------AVVWELPPHAG-AQAGGDVLAAVY
Mb1689|M.bovis_AF2122/97            GGDIGDD-------------------AVVWELPPHAG-AQAGGDVLAAVY
MMAR_2471|M.marinum_M               GDDTADIP------------------VTLWDLASQVE-LSAG--AVESTY
MAV_3109|M.avium_104                GNDLGDE-------------------VTLWEPG------EHGGDVVKSVH
MUL_2266|M.ulcerans_Agy99           ATDAAPAY------------------ELFESIA-------ADGDPLSGTY
MLBr_00135|M.leprae_Br4923          SDGHGGGLPSVVSWADYCAGRGNDTGVVVWEFGSASAGAQAPVDSVAAVY
TH_4621|M.thermoresistible__bu      TADVSATRLSDALKQAGAESTSMCWPQQADHADNVDRFRAGIADGVTGVV
                                                                                 : .  

Mflv_0405|M.gilvum_PYR-GCK          HAAGEIGTTPLADLD--------------------DAEVDRVFAGKVWGA
MAB_0939|M.abscessus_ATCC_1997      HAAGEIGTTPLSDLE--------------------DAEVDRVFAGKVWGA
MSMEG_0408|M.smegmatis_MC2_155      HAAGEIGTTPLSGLD--------------------DAEVDRVFAGKVWGA
Mvan_1003|M.vanbaalenii_PYR-1       HAAGEIGTSPLRTLD--------------------DAEMDRVFAGKVWGA
Rv1661|M.tuberculosis_H37Rv         RGVHEVLEVLQSWLA--------------------SDATGLGVVVTRGAV
Mb1689|M.bovis_AF2122/97            RGVHEVLEVLQSWLA--------------------SDATGLGVVVTRGAV
MMAR_2471|M.marinum_M               VATHGALGALQSWLA--------------------SDQPGVLAVVTHGAV
MAV_3109|M.avium_104                AAVTETLAVLQSWLD--------------------GEGAGVLAVQTHGAV
MUL_2266|M.ulcerans_Agy99           QRTHQALAAVQSWLT--------------------EHDSGVLVVATRGAM
MLBr_00135|M.leprae_Br4923          SATHAALQVLQFWFG--------------------QDRAGTLVVLTRGAV
TH_4621|M.thermoresistible__bu      VLTGPKNGNPDDAAARRGSDYVRHLVRITRELAEIDGDAPRLFVVTRGAQ
                                      .                                        . .  . 

Mflv_0405|M.gilvum_PYR-GCK          WHLSEATSDLQ--LDFFISTSSIASVWGGFGQAAYGAANAFLDGL-AWRL
MAB_0939|M.abscessus_ATCC_1997      WHLSEAAAGLK--LDFFINTSSIAAVWGGYGQTAYSAANAFLDGL-AWRL
MSMEG_0408|M.smegmatis_MC2_155      WHLSEALTDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGL-AWRL
Mvan_1003|M.vanbaalenii_PYR-1       VYLCEEVADMG--LDFFLATSSIASVWGSHGQTAYGAANAFLDGL-ADSL
Rv1661|M.tuberculosis_H37Rv         GPVDDDVTDLAG-----------AAVWG-----LVRSAQAEHPGR-VVLV
Mb1689|M.bovis_AF2122/97            GPVDDDVTDLAG-----------AAVWG-----LVRSAQAEHPGR-VVLV
MMAR_2471|M.marinum_M               GLADEDVTDLAG-----------SAVWG-----LVRSAQAEHPGR-VVLV
MAV_3109|M.avium_104                ALAGEDVSDLAG-----------AAVWG-----LVRSAQAEHPGR-LVLI
MUL_2266|M.ulcerans_Agy99           ALAGEDVTDLAG-----------AAVWG-----LVRSAQTENPGR-LVLV
MLBr_00135|M.leprae_Br4923          GLVGEGISDLAA-----------AAVWG-----MVRSAQSEHSGK-IVLI
TH_4621|M.thermoresistible__bu      AVLPQDRPNLEQ-----------AGLRG-----LLRVIGAEHPHLRTTQI
                                        :  ..:             :.: *           :         :

Mflv_0405|M.gilvum_PYR-GCK          REQGVAGVSVNFGPWSAGMADAQSRARLEQRGIKTLSPADALA----GLS
MAB_0939|M.abscessus_ATCC_1997      REQGIAGTSVNFGPWSAGMADAESRARLEQRGIKTLSPTDALA----GLA
MSMEG_0408|M.smegmatis_MC2_155      RERGVTAVSVNFGPWAAGMADAESRARLEQRGVRTLSPAEALA----GMA
Mvan_1003|M.vanbaalenii_PYR-1       RARGIPGISVNFGPWAAGMADAKAREQLSRRGVKTLAPADALA----GMA
Rv1661|M.tuberculosis_H37Rv         DTDGSVAVEDAVGFGAR-SGEPQLVVRRGRVYAARLAPVAAG-----LTL
Mb1689|M.bovis_AF2122/97            DTDGSVAVEDAVGFGAR-SGEPQLVVRRGRVYAARLAPVAAG-----LTL
MMAR_2471|M.marinum_M               DTDGSVELGAVL----N-SGEPQLVVRAGVAYQARLKPAESL-----LRL
MAV_3109|M.avium_104                DSDGSLDARAVIP-----CGEPQVVVRQGVAHAARLRPARAG-----ATL
MUL_2266|M.ulcerans_Agy99           DSDAAVDAAAVAT-ALA-VGEPQVVLRNGQPYTARVHASRAAD----GIL
MLBr_00135|M.leprae_Br4923          DTDSAVDVAVLAD-----LGESQLLVRCNTVHAARLSPAPQL------LA
TH_4621|M.thermoresistible__bu      DIADDADLDRVAVQLLGGGAEDETAWRDGQWYTARLSLSPLRPEERKQAV
                                                       .: :   :        :              

Mflv_0405|M.gilvum_PYR-GCK          DAVISAAP---HPVVARVDWSRFLPLYQQAGRRGFLAELERELPAAPAQQ
MAB_0939|M.abscessus_ATCC_1997      DVVAASGSNAVQGVIARIDWARFLPLYQQAGKRGFLAELDREVPSHLA--
MSMEG_0408|M.smegmatis_MC2_155      DVVAGPVQ----GVVAKIDWSRFLPLYQQAGRRAFLSELESELPAAATGA
Mvan_1003|M.vanbaalenii_PYR-1       DVIAASTA---HAVVARIDWATFLPVYQLQRRRAFLSQLEREVPDVPD--
Rv1661|M.tuberculosis_H37Rv         PSASAGGWRLVAGGGGTLADVVVAPVAPV------------ELATGQVRV
Mb1689|M.bovis_AF2122/97            PSASAGGWRLVAGGGGTLADVVVAPVAPV------------ELATGQVRV
MMAR_2471|M.marinum_M               PPPGEN-WRLVTGGGGTLDDVKVGGCAPS------------GLMTGQLRV
MAV_3109|M.avium_104                G-LPSGAWRLDAGGEGTLGDLVVSRCPRT------------ELADGQVRV
MUL_2266|M.ulcerans_Agy99           VPPVDGPWRLGLSSAGTFENLQLEPVPNAGA----------PLGPGQVRV
MLBr_00135|M.leprae_Br4923          LPVGESMWRLAADGGGTLEDLVIQPCPEVQA----------PLQAGHMRV
TH_4621|M.thermoresistible__bu      VDCERDGMRLEIRTPGDLETMELAAFDRVPP------------GPGQIEV
                                                   . .    .                           

Mflv_0405|M.gilvum_PYR-GCK          GPAVTASGRTPLVERLTTAP-LQQRKRLLTDYLRDAVAEVTRVDAAEIRE
MAB_0939|M.abscessus_ATCC_1997      GVAGAQSGSTQLVERLANAP-VQQRKKLLTDYLRDAVAEVTRVDVSEIRE
MSMEG_0408|M.smegmatis_MC2_155      AAPATVPGKPPLVEQLTKAP-VQQRKSLITNYLRNAVAEVTRVDADEIRD
Mvan_1003|M.vanbaalenii_PYR-1       ASAPAPSGTTRFVEELTLAP-VEQRRKLVLEYLRAAVAEVTRVDAAEIRD
Rv1661|M.tuberculosis_H37Rv         AVGAVGVNFRDVLVALGMYP-GGGE---LGVDGAGVVVEVGPGVTGLAVG
Mb1689|M.bovis_AF2122/97            AVGAVGVNFRDVLVALGMYP-GGGE---LGVDGAGVVVEVGPGVTGLAVG
MMAR_2471|M.marinum_M               AVAAVGVNFRDVLVALGMYP-GGGE---LGVEGAGIVTEVGPGVSGVAVG
MAV_3109|M.avium_104                AVAAVGVNFRDVLVALGMYP-GGGR---LGAEGAGVVVEVGPAVTGLAVG
MUL_2266|M.ulcerans_Agy99           AMRAIAANFRDIMITLGMFT-HDAL---IGGEGAGVVVEIGPEVTEFAVG
MLBr_00135|M.leprae_Br4923          AVAAVGVNFRDVVAALGMYP-GQAPP--LGAEGAGVVIEIGPEVTGVAVG
TH_4621|M.thermoresistible__bu      AVTASSINFADVLIAFGRYPTFDGRRPQLGTDFAGVVTAVGPDVTSHRVG
                                    .      .   .:  :   .        :       *  :          

Mflv_0405|M.gilvum_PYR-GCK          DAGFFDLGM-DSLMAVELRRRIETGVGKEIPVTLVMDHPRLSDAADYLLG
MAB_0939|M.abscessus_ATCC_1997      DAGFFDLGM-DSLMAVELRRRMEQGVGKEIPVTLVMDHPRISDVADYLLG
MSMEG_0408|M.smegmatis_MC2_155      EAGFFDLGM-DSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLV
Mvan_1003|M.vanbaalenii_PYR-1       EAGFFDLGM-DSLMAIELRRRLEQGLGKELPVTLAMDHPHLSDAAEYVLG
Rv1661|M.tuberculosis_H37Rv         DRVMGLLG--LVGSEAVVDARLVTMVPAGWSLVEAAAVPVAFLTAFYGLS
Mb1689|M.bovis_AF2122/97            DRVMGLLG--LVGSEAVVDARLVTMVPAGWSLVEAAAVPVAFLTAFYGLS
MMAR_2471|M.marinum_M               DAVMGLLG--VVGPEAVVDHRLVTAVPPGWSLQTAASVPVVFLTAFYGLR
MAV_3109|M.avium_104                DPVMGLLG--VVGSEAVVDQRLLTAVPPGLSLVAAAGVPVVFLTALYGLS
MUL_2266|M.ulcerans_Agy99           DAVYGFFPD-GSGTLVAGDVRLLLPKPADWSYAEAAAISAVFTTAYYAFV
MLBr_00135|M.leprae_Br4923          DAVMGFLG--GAGPLAVVHQQLITQMPQGWSLAEAAAVPVVFLTALFGLA
TH_4621|M.thermoresistible__bu      DRVGGLSPNGCWSTFVTCDADLAVPLPDGLTEGQAAAVSTAHATAWYGLH
                                    :                    :        .   .   .    .* : : 

Mflv_0405|M.gilvum_PYR-GCK          DVLGLTEAAT-APKAATVVSTAADEPIAIVAVSCRFPGAPNPEAFWDLLS
MAB_0939|M.abscessus_ATCC_1997      DVLGLAEQAKPAAQLASAVTGRTDEPIAIVAVSCRFPGAPDPEAFWDVLS
MSMEG_0408|M.smegmatis_MC2_155      EVLGLGEQTN--VRQASTVTARTDDPIAVVAVSCRFPGAPDPESFWELLA
Mvan_1003|M.vanbaalenii_PYR-1       DVLGLSEHTV--AQPDTPSTVRTDDPIAIVGMACRFPGADDTDAFWSVLA
Rv1661|M.tuberculosis_H37Rv         VLAEVAAGQK-----VLVHAGTGGVGMAAVSLARYWG----AEVFVTASR
Mb1689|M.bovis_AF2122/97            VLAEVAAGQK-----VLVHAGTGGVGMAAVSLARYWG----AEVFVTASR
MMAR_2471|M.marinum_M               VLAEVRSGQK-----LLVHAATGGVGMAAVQLARLWG----LEVFATASP
MAV_3109|M.avium_104                VLSGLRPGER-----VLVHTATGGVGMAAVQLARHYG----AEVFATASR
MUL_2266|M.ulcerans_Agy99           HLANVQPGQR-----VLVHAATGGVGMAAVQLARHLG----LEVYATASK
MLBr_00135|M.leprae_Br4923          DLAGIRAGES-----VLIHAGTGGVGMAAVQFARHWG----VEIFVTASR
TH_4621|M.thermoresistible__bu      DLARLGAGEK-----VLIHSATGGVGLAAIAIARSVG----AQIYATAGS
                                     :  :              :   .  :* : .:         : :     

Mflv_0405|M.gilvum_PYR-GCK          -GGVDAIREVPEDRFDIDEFYDPDPDAAGKTYTRYGGFLDHIDEFDPEFF
MAB_0939|M.abscessus_ATCC_1997      -GGVDAIREVPEDRFDIDEFYDPDPEVAGKTYTRFGGFLDGIDGFDPEFF
MSMEG_0408|M.smegmatis_MC2_155      -GGVDAIREVPEDRWDIDEFYDPDPDTPGKTYTRFGGFLDGIDGFDPEFF
Mvan_1003|M.vanbaalenii_PYR-1       -EGADLIREIPDDRFDINEFYDPDPEAAGKIYSRYGGFLDGVDGFDPEFF
Rv1661|M.tuberculosis_H37Rv         -AKWDTLRAMGFDDIHISDSRSLEFEEAFLRATEGSGVDVVLNSLAGEFT
Mb1689|M.bovis_AF2122/97            -AKWDTLRAMGFDDIHISDSRSLEFEEAFLRATEGSGVDVVLNSLAGEFT
MMAR_2471|M.marinum_M               -GKWDTLRAMGFDDDHIANSRTLEFEEKFRAGTGGVGVDAVLNSLAGEFV
MAV_3109|M.avium_104                -GKWDTLRAMGFDDDHIGDSRSPDFEQKFLAATGGAGVDVVLNSLAGEFT
MUL_2266|M.ulcerans_Agy99           -GKWDILRAMGFDEDHISDSRSLEFEEKFREVTGGRSVDVVLDSLAGEFV
MLBr_00135|M.leprae_Br4923          -GKWDTLRDMGFDDDHIGDSRTLEFEEKFLAVTDGRGVDVVLDSLAGDFV
TH_4621|M.thermoresistible__bu      PARRDLLRDMG--IEHVYDSRSTAFADEIRRDTDGYGVDVVLNSLP----
                                        * :* :     .: :             :   ..   :: :     

Mflv_0405|M.gilvum_PYR-GCK          GLSPREAVWIEPQQRLMLETVWEGLERAGYAPSALRGSRTGVFVGVAA--
MAB_0939|M.abscessus_ATCC_1997      GISPREAVWIEPQQRLMLETVWEGLERAGYSPAALRGSRTGIFAGVGA--
MSMEG_0408|M.smegmatis_MC2_155      GISPREAVWIEPQQRLMLETVWEGLERAGYAPSDLRGSRTGVFTGVAA--
Mvan_1003|M.vanbaalenii_PYR-1       GISPREAVWIDPQQRLVLETAWEGLERAGYSAAALRGSRSGVYVGVGA--
Rv1661|M.tuberculosis_H37Rv         DASLR----LLPSGGRFIELGKTDIRDGQTVAERHRGVR---YRAFDL--
Mb1689|M.bovis_AF2122/97            DASLR----LLPSGGRFIELGKTDIRDGQTVAERHRGVR---YRAFDL--
MMAR_2471|M.marinum_M               DASLR----LLVPGGRFIEMGKTDLRDPQTMAEQHRGVG---YRAFDL--
MAV_3109|M.avium_104                DASLR----LLAPGGRFIEMGKTDVRDPDVVAQRYRGAR---YRAFDL--
MUL_2266|M.ulcerans_Agy99           DASLR----LLGPGGVFLEMGKTDIRDPGVIAQEYPGVR---YRAFDL--
MLBr_00135|M.leprae_Br4923          DASLR----LLVRGGRFLEMGKTDIRDAQEIAANYPGVQ---YRAFDL--
TH_4621|M.thermoresistible__bu      GAAQRAGLELLSFGGRFIEIGKRDIYG-DTRLGLFPFRRNLAFHGVDLGL
                                    . : *    :      .:*    .:                 : ..    

Mflv_0405|M.gilvum_PYR-GCK          -NEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGLEGPAVAVDTAC
MAB_0939|M.abscessus_ATCC_1997      -NEYAHLLSSESIDKIEPYFITGNALNAISGRVAFALGFEGPAVAVDTAC
MSMEG_0408|M.smegmatis_MC2_155      -NEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGFEGPAVAVDTAC
Mvan_1003|M.vanbaalenii_PYR-1       -NEYSHLLSGGSLDGIEAQFITGNALNVIAGRVSFTLGLEGPAVAVDTAC
Rv1661|M.tuberculosis_H37Rv         -VEAGPDRIAAMLSEVVGLLAAGVLARLPVKTFDARCAPAAYRFVSQARH
Mb1689|M.bovis_AF2122/97            -VEAGPDRIAAMLSEVVGLLAAGVLARLPVKTFDARCAPAAYRFVSQARH
MMAR_2471|M.marinum_M               -IEAGPDLIARMLAELSRLLCAETLTPLPIKTFDVRLARQAYRFVSQARH
MAV_3109|M.avium_104                -MEAGPDRTAAMLAEIVGLLRAGVLTPLPLKTFDVRCASTAYRYVSQARH
MUL_2266|M.ulcerans_Agy99           -FEPGRPRMHQYMLDLAGLFDAGVLRPLPVTAFDVRRAPAALRYLSQARH
MLBr_00135|M.leprae_Br4923          -SEAGPVRMQEMLCEVRELFDTQVLHRLPVTSWDVRCAPAAFRFMSQARH
TH_4621|M.thermoresistible__bu      MADSHPHKIRELLETVYRLTADGVLPMPQSTHYPLAEAATAIRVMSAAEH
                                      :         :  :                     .  .      :  

Mflv_0405|M.gilvum_PYR-GCK          SSSLVAVHQATQALRSGDCDMALAGGVNVLLSPVTVVAASRARMLSPVGR
MAB_0939|M.abscessus_ATCC_1997      SSALVAVHQAVQALHSGDCDLALAGGVNVLLSPVTVIAASRARMLSPVGR
MSMEG_0408|M.smegmatis_MC2_155      SSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGR
Mvan_1003|M.vanbaalenii_PYR-1       SSSLVAVHQACQGLQSGDCDLALAGGVNVLLSPATTIATSRARMLSPDGR
Rv1661|M.tuberculosis_H37Rv         IGKVVLTIPDGPGGQSG-----LAGGTVVVTGGTGMAGSAVATHLVRRHG
Mb1689|M.bovis_AF2122/97            IGKVVLTIPDGPGGQSG-----LAGGTVVVTGGTGMAGSAVATHLVRRHG
MMAR_2471|M.marinum_M               IGKVVLTLPDETGAVPAGA---LAGGTVIITGGTGMAGTALARHVVSRHR
MAV_3109|M.avium_104                IGKVVLTVPSGPGEVLSGCGGGLAQSTVLITGGTGMAGSALARHLVDRYR
MUL_2266|M.ulcerans_Agy99           VGKVVMTMPADQGGALG-------GGTVLITGGTGMAGSALARHLVAHHG
MLBr_00135|M.leprae_Br4923          IGKVVLTMPSALADGLA-------EGTVLITGASGAIGGVLARHMVSAYG
TH_4621|M.thermoresistible__bu      VGKLVLDVPHTG-----------RADVVVPPEQASPFRSDGAYIVTGGMG
                                     . :*                    .. :            *  :     

Mflv_0405|M.gilvum_PYR-GCK          CKTFDASADGYVRSEGCGILVLKRLSDAVRDGDRVCAVIAGSAVNQDGAS
MAB_0939|M.abscessus_ATCC_1997      CKTFDASADGYVRSEGCGILVLKRLSDAERDGDRVLAVIPGSAVNQDGAS
MSMEG_0408|M.smegmatis_MC2_155      CKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGAS
Mvan_1003|M.vanbaalenii_PYR-1       CKTFDAAADGYVRGEGCGILVLKRLSDAVRDGDRIQAVIRGSAVNQDGAS
Rv1661|M.tuberculosis_H37Rv         VANLVLVSRSGEQADRA-----AEVAALLREGGAQVAVVSCDVADRD-AL
Mb1689|M.bovis_AF2122/97            VANLVLVSRSGEQADRA-----AEVAALLREGGAQVAVVSCDVADRD-AL
MMAR_2471|M.marinum_M               VANVILVSRSGAQAEGT-----SELLGQLQDAGAEAAVVACDVSDRD-AV
MAV_3109|M.avium_104                VGHVVLVSRTGAQAAGA-----AELVDELQRAGASASVLACDVGDRD-AV
MUL_2266|M.ulcerans_Agy99           VAHLVLISRRGPAAPGA-----TELVAELSAAGAQVEVVACDAADRP-AL
MLBr_00135|M.leprae_Br4923          VRHLVLASRRGDRAEGA-----VELAAELVGAGAKIQVVACDVADND-AV
TH_4621|M.thermoresistible__bu      GLGLYLAGEMAAAGA-G------CIVLNGRSAPSGEALRTIEQLRAAGTE
                                       .   .     .          :      .     :   .      : 

Mflv_0405|M.gilvum_PYR-GCK          SGLTVPNGGAQQRLIGTVLARAGITGGEVDYLEAHGTGTPLGDPIEVQAA
MAB_0939|M.abscessus_ATCC_1997      SGLTVPNGGAQQRLIGSVLARAGLVGGDVDYLEAHGTGTPLGDPIEVQAA
MSMEG_0408|M.smegmatis_MC2_155      SGLTVPNGGAQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQAA
Mvan_1003|M.vanbaalenii_PYR-1       GGLTVPNGGAQQRVIAAALTRAGLSGSDIDYLEAHGTGTSLGDPIEVQAA
Rv1661|M.tuberculosis_H37Rv         AALLAGLDPRYP-LKGVFHAAGVLDDAVITGLTPDRVDTVLRAKVDGAWN
Mb1689|M.bovis_AF2122/97            AALLAGLDPRYP-LKGVFHAAGVLDDAVITGLTPDRVDTVLRAKVDGAWN
MMAR_2471|M.marinum_M               AELLAQVPARYP-LRGVIHAAGVLDDGLIASLTPQRVDTVLRAKIDGAWN
MAV_3109|M.avium_104                ATMLAGLPSGYP-LRGIVHAAGILDDGLLSSLTPDRVDAVLRAKVDGAWN
MUL_2266|M.ulcerans_Agy99           AKVIAENPAQRP-LSAVVHAGGVLDDAVISSLTPERVDTVLRAKVDAAWN
MLBr_00135|M.leprae_Br4923          RGLFAQLSREFPPVRGVIHAAGVLDDGAITSLTPDRVDTVLRAKVDAAWN
TH_4621|M.thermoresistible__bu      VIVECGXXXRGQPVEVAVPTELRHADEHPDRRGAQLCDEFARGEQGAQRN
                                      :          :     :     .       ..  .            

Mflv_0405|M.gilvum_PYR-GCK          AAAYAGARDADRPLLMGSVKTNIGHTESASGAAGLIKVVLSLQHETLPQS
MAB_0939|M.abscessus_ATCC_1997      AAAYGGSRDADRPLLMGSVKSNIGHTESASGAAGLIKVVLSLQNGVLPQS
MSMEG_0408|M.smegmatis_MC2_155      AAAYGAGRDADRPLLMGSVKTNIGHTESASGAAGLIKVVLSLQHGVLPQS
Mvan_1003|M.vanbaalenii_PYR-1       GAVLGAGRDPDRPLLMGSVKTNVGHLESASGVAGLIKVVLSLQHEMLPRH
Rv1661|M.tuberculosis_H37Rv         LHELTEDMDLSAFVVFSSMAGIVGTPAQGN-----YAAANAFLDGLVAYR
Mb1689|M.bovis_AF2122/97            LHELTEDMDLSAFVVFSSMAGIVGTPAQGN-----YAAANAFLDGLVAYR
MMAR_2471|M.marinum_M               LHELTRGLNLSAFVLFSSMAGIIGTAGQGN-----YAAANSFLDGLAVHR
MAV_3109|M.avium_104                LHELTKDLDLSAFVVFSSMAGIVGTPGQAN-----YAAANSFLDGLVAHR
MUL_2266|M.ulcerans_Agy99           LHELTRDLDLSAFVMFSSMAGVVGSSGQAN-----YAAANTFVDGLAAHR
MLBr_00135|M.leprae_Br4923          LHEATRDLDLLMFVLCSSIAATVGSPGQGN-----YSAANAFLDGLAAYR
TH_4621|M.thermoresistible__bu      QHRTDAGEGQRDAHPPGAVGHDQPDPGALS-------------------D
                                            .       .::          .                    

Mflv_0405|M.gilvum_PYR-GCK          LHFDTPSPHIPWDSLPVRVVDTAMPWQPNGRPRRAGVSSFGFTGTNAHVL
MAB_0939|M.abscessus_ATCC_1997      LHFDNPSPHIPWESLPVRVVDKAIPWQANGRPRRAGVSSFGFTGTNAHVL
MSMEG_0408|M.smegmatis_MC2_155      LHFENPSPHIPWDALPVRVIDEPVPWQTNGRVRRAGVSSFGFTGTNAHVL
Mvan_1003|M.vanbaalenii_PYR-1       LHFKTPSPHIPWDRLAVRVVAEPTPWRADGRPRRAGVSSFGFSGTNAHVV
Rv1661|M.tuberculosis_H37Rv         RSRGLAGLSVAWG-LWEQASAMTRHLGERDRARMTQAGLAPLTTEQALGF
Mb1689|M.bovis_AF2122/97            RSRGLAGLSVAWG-LWEQASAMTRHLGERDRARMTQAGLAPLTTEQALGF
MMAR_2471|M.marinum_M               RALGLPGVSVAWG-LWEQASAMTRHLGERDKARMSRVGLATLSTEHALEL
MAV_3109|M.avium_104                RADGLAGLSLAWG-LWEQASAMTAHLGDRDKARMSRIGLAPLSTEQALAA
MUL_2266|M.ulcerans_Agy99           RAHGLPAISLGWG-LWDQASDMTGGMDAADRARLGREGVLALSSDEAMEL
MLBr_00135|M.leprae_Br4923          QAAGLAGTSLAWG-LWEQPGGMNAHLSSRDLARISRSGLAPMNPAQALEL
TH_4621|M.thermoresistible__bu      TGLDERGGQFPGVGVQIPVADPGVGIDHRGAVRVDSGVPAQQG-------
                                          .  .    :              .  *                 

Mflv_0405|M.gilvum_PYR-GCK          IEEAPTDLAGPTEPTAPAEPVDEDAAADPAPAPVEVLPLSARSPEALVAL
MAB_0939|M.abscessus_ATCC_1997      IEEAPQPQATP----------DEDDASTPQSAPVSVLPLSARSPEALAAV
MSMEG_0408|M.smegmatis_MC2_155      VEEAPPQLHTADAAP----VEPAATAEAGTDDSPQVLALSARSPEALVEL
Mvan_1003|M.vanbaalenii_PYR-1       LEEPPAQSADLRQPPTDGKDGAAGLESATAPEPAGVLPISARSPEALTAL
Rv1661|M.tuberculosis_H37Rv         LDTALQADRAVVVAAR--------LDRAALAGAGAA--LPALFSQLAAGP
Mb1689|M.bovis_AF2122/97            LDTALQADRAVVVAAR--------LDRAALAGAGAA--LPALFSQLAAGP
MMAR_2471|M.marinum_M               FDAAVVADRAVVVATR--------LDANALKSNSAA--LPPLLGELAARP
MAV_3109|M.avium_104                FDAAMLVETPVLVAAR--------LDRAALSENIAA--LPPLLRELAAGP
MUL_2266|M.ulcerans_Agy99           FDTALIVNQAFLAPAR--------IDLAALRAHAVA--VPPMFSDLVSAP
MLBr_00135|M.leprae_Br4923          FDAALVIDHPFMVTAL--------LDRAALDAQAQAGALPPLFSRLVRRS
TH_4621|M.thermoresistible__bu      ------------------------VDGEVVRHRTLSSVRSGRSSRWTAPG
                                                                           .          

Mflv_0405|M.gilvum_PYR-GCK          AQRYETWLTAHPEADLADVCRTAGTGRSHFEHRAALVVDSVESARIALTD
MAB_0939|M.abscessus_ATCC_1997      AQRYESWLAAHPDVDLEDVCLTAGRGRSHFEHRAALVVDSIQTAREGLLE
MSMEG_0408|M.smegmatis_MC2_155      ARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVDSVERAREGLAA
Mvan_1003|M.vanbaalenii_PYR-1       ARRYESWLTAHPDADIADVCYTAGAGRSHFEHRAALVVDSVDGARDLLAG
Rv1661|M.tuberculosis_H37Rv         TRRRI---DAADTAVSMSGLVSRLHALTPERRQRELTDLVISNAAAVLGR
Mb1689|M.bovis_AF2122/97            TRRRI---DAADTAVSMSGLVSRLHALTPERRQRELTDLVISNAAAVLGR
MMAR_2471|M.marinum_M               KRRVISDADAGDNIAAATGLVARLHGLSAEQRQRELVDVVCSNAATVLGR
MAV_3109|M.avium_104                TRRVI---DDADVTASMSGLAARLHGLSPEARRRELVDLVCGNAAMVLGV
MUL_2266|M.ulcerans_Agy99           TRRQID--AALATAKSKSALAHRLHGLPELEQHAVVLDLVRSHIATVLGT
MLBr_00135|M.leprae_Br4923          RRRQIE--DPGDATQSKLALVQRLQGLAANRQLELLVGVVCLQAAAVLGR
TH_4621|M.thermoresistible__bu      SRCGSGRRYGGESCRRTTGPAAGAAARRGRTRRRRRPRRPPPPPDRVRHR
                                     :                       .                        

Mflv_0405|M.gilvum_PYR-GCK          LAQNRLRPGVVRGEHLNHPTTAWMFTGQGSQYPGMARELFDTEPVFADTV
MAB_0939|M.abscessus_ATCC_1997      LAQNRLRPGVVRGEHTNHPTTAWLFTGQGSQYPGMARELFDAEPVFAETV
MSMEG_0408|M.smegmatis_MC2_155      LAEGRTPAGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTV
Mvan_1003|M.vanbaalenii_PYR-1       LAEDRLGPGAVRGVCGDPPKTAWLFTGQGSQYPGMARELFDTEPVFRDTV
Rv1661|M.tuberculosis_H37Rv         SSSVDINAHKAFQDLGFDSLTAVELRNRLKTATGLT--LSPTLIFDYPTP
Mb1689|M.bovis_AF2122/97            SSSVDINAHKAFQDLGFDSLTAVELRNRLKTATGLT--LSPTLIFDYPTP
MMAR_2471|M.marinum_M               SSTADINAHRAFQELGFDSLTAVELRNRLKTATGLT--LSPTLIFDYPSP
MAV_3109|M.avium_104                PDPADINAGRAFQDLGFDSLTAVELRNRLKNATGLT--LSPTLIFDYPTP
MUL_2266|M.ulcerans_Agy99           ITPEAIDPDKAFQELGFDSLTAVEMRNRIKTVTGLS--LSPTLIFDYPTP
MLBr_00135|M.leprae_Br4923          PSPEDIDPNTKFQDLGFDSLTAVELRNRLKSATGLT--LPPTVIFDHPTP
TH_4621|M.thermoresistible__bu      AGPAHGPVRR----------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          TRCADAVADLLPRPLLDVMFAGGREAGV----------------------
MAB_0939|M.abscessus_ATCC_1997      TRCAEAVKDIVTRPLLEVMFATDRETGG----------------------
MSMEG_0408|M.smegmatis_MC2_155      RQCAEAVADMLPRPLLDVLFATDRET------------------------
Mvan_1003|M.vanbaalenii_PYR-1       TRCAEAIGDTLPRPLLEVLFDTDGDN------------------------
Rv1661|M.tuberculosis_H37Rv         ATLAEHLDSRLVTASGSDQQSLSDRVD-----------------------
Mb1689|M.bovis_AF2122/97            ATLAEHLDSRLVTASGSDQQSLSDRVD-----------------------
MMAR_2471|M.marinum_M               AALAEHLGIRLATAT--AQPDLMRRFD-----------------------
MAV_3109|M.avium_104                VVLAEHLDSRLAGSGGDDQPDLMGRFN-----------------------
MUL_2266|M.ulcerans_Agy99           NGLANYIRAELAGAPQEVKHTPAVRVTGDDPIAIVGMSCRYPGGIESPDD
MLBr_00135|M.leprae_Br4923          TAVAEYVAQQMLKSR-----------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          -----------------PPTETLRHTS-----------------------
MAB_0939|M.abscessus_ATCC_1997      -----------------KAGEALRHTS-----------------------
MSMEG_0408|M.smegmatis_MC2_155      -------------------ADLLQHTS-----------------------
Mvan_1003|M.vanbaalenii_PYR-1       -------------------GQTLRHTS-----------------------
Rv1661|M.tuberculosis_H37Rv         -----------------DITRELVVLLD-QPDLS----------------
Mb1689|M.bovis_AF2122/97            -----------------DITRELVVLLD-QPDLS----------------
MMAR_2471|M.marinum_M               -----------------DLARELDKLIN-RPDWT----------------
MAV_3109|M.avium_104                -----------------DITRELQALLG-APHWN----------------
MUL_2266|M.ulcerans_Agy99           LWDMLMARRDVLSDFPADRGWDLAGLFNPDPDVPGACYTRTGGFVDRVGD
MLBr_00135|M.leprae_Br4923          ----------------------PAES------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          ---------FAQPALFAVEMGLARLWQSWGIVPDVVLGHSVGQYAAACVA
MAB_0939|M.abscessus_ATCC_1997      ---------FAQPALFAVEMGLARLWQSWGIEPDVVLGHSVGQYAAACVA
MSMEG_0408|M.smegmatis_MC2_155      ---------FAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACVA
Mvan_1003|M.vanbaalenii_PYR-1       ---------YAQPALFAIEMGLARLWQARGIEPDVVLGHSVGQYAAACVA
Rv1661|M.tuberculosis_H37Rv         --------ANVKAHLRTRLQTMLTSLTT--------EDDDIAAATESQLF
Mb1689|M.bovis_AF2122/97            --------ANVKAHLRTRLQTMLTSLTT--------EDDDIAAATESQLF
MMAR_2471|M.marinum_M               --------HEDKGKLSGRLHDILADLS---------ADDDITTASESQLF
MAV_3109|M.avium_104                --------SDDKAVLRARIHGLLGALPAGDGPDSAPLDEDLEAATESQLF
MUL_2266|M.ulcerans_Agy99           FEPAFFGVGPSEALAMDPQQRMFLELSWEALERAGIEPGGLRGSATGVFA
MLBr_00135|M.leprae_Br4923          -------------------------------------GDETSQAVEPKVE
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          GVFSLEDGAR----------------------------------------
MAB_0939|M.abscessus_ATCC_1997      GVFSIEDGAR----------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      GVFSLDDGAR----------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       GVFGLEDGAR----------------------------------------
Rv1661|M.tuberculosis_H37Rv         AILDEELGS-----------------------------------------
Mb1689|M.bovis_AF2122/97            AILDEELGS-----------------------------------------
MMAR_2471|M.marinum_M               AILDEELGS-----------------------------------------
MAV_3109|M.avium_104                AILDEELGR-----------------------------------------
MUL_2266|M.ulcerans_Agy99           GVMTQGYGMFAAEPVEGFRLTGQLSSVASGRVAYVLGLEGPAVSVDTACS
MLBr_00135|M.leprae_Br4923          EVSVHA--------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           SSLVALHMAVQSLRSGECDLALAGGVTINATPDIFVEFSRWRGLSADGRC
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           KAFAGAADGTGFSEGGGMLVVERLSDAQRLGHPVLALVRGSAVNQDGASN
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           GLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTTLGDPIEAQALL
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           ATYGQDRGSAGAAGKALWLGSIKSNMGHTQAAAGVAGVIKMVQAMRHEVL
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           PATLHVDVPSPHVDWSAGAVELLTEAQPWPAESAGDRVRRAGVSSFGISG
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           TNAHVIVEAAPRVEVGGSSGGAVPVVPWVVSAKSGSALGAQAARLAAHVR
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           SHDELDVADVGWSLAGRSTFEHRAVVLGADRDGLLAGLDELAGDEFGGAS
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           VIRGVAGAAGKTVFVFPGQGSQLLGMGMGLHAGYPVFAEAFNTVVGELDR
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           HLLRPLREVIWGHDENLLNTTEFAQPALFAVEVALYRLLESWGVRPDFVM
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          -----------------------LMAERGRLFGSLPEGGRMVAVFADAKR
MAB_0939|M.abscessus_ATCC_1997      -----------------------LIAERGRLFGGLPAGGRMVAVFSDAKH
MSMEG_0408|M.smegmatis_MC2_155      -----------------------LMAERGRMFGSLPEGGRMVAVFADAEH
Mvan_1003|M.vanbaalenii_PYR-1       -----------------------LVADRGRLFGGLPVGGRMVAVFTDAEV
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           GHSVGELSAAHVAGVLSLENAAVLVAARGRLMQALPDGGAMIAVQATEQE
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          VEQVAADFPRVSVGAYNGPNTVLSGPGEDLEQIVGTFGEDGIRCTWLETS
MAB_0939|M.abscessus_ATCC_1997      VEQIAGEFPRVSVGAYNGPNTVLSGPGEDLEQAVARFQEEGIRCTWLETS
MSMEG_0408|M.smegmatis_MC2_155      VEQVAGEFPRVSVGAYNGPNTVLSGPGEDLEEIVERFEDEGIRCTWLATS
Mvan_1003|M.vanbaalenii_PYR-1       VEDFADEFPQVSVAAYNGPNTVLAGPASDLEQIVAGCSGEGIRTTWLDTS
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           VLPLLGAQVSIAT-INGPASVVISGAQDAVSAVAEQLRADGRRVHRLAVS
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          HAFHSELLDPVLDEFESYAAQLQFAAPTLPLVCNRTGAVLTGQTSLDAQY
MAB_0939|M.abscessus_ATCC_1997      HAFHSELLDPILDEFESYAAQVQFAAPTLPLVCNRTGAVLTAQTPIDGQY
MSMEG_0408|M.smegmatis_MC2_155      HAFHSELLDPVLDEFEAYAAQFQFAAPTLPLVCNRTGAVLTGQTPLDAQY
Mvan_1003|M.vanbaalenii_PYR-1       HAFHSALLDPVLDEFESCAARLAYAAPTRPLVCNRTGAVVTGPGVIDAQY
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           HAFHSPLMDPMIDEFATVAGELTVNAPTIGIISNLT-GQLAGEDFGSAAY
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          WRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHLAAP
MAB_0939|M.abscessus_ATCC_1997      WRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHLAPP
MSMEG_0408|M.smegmatis_MC2_155      WRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHMAAP
Mvan_1003|M.vanbaalenii_PYR-1       WRRHARQPVQFAESVRTLADLGCSVLMEIGPQPFLIAAALRVWPESAATP
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           WKRHVRDAVRFADSIRFAQSAGAARFLEVGPSIGLTASIEEVLSDAAVTN
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          --RAIASLRKGVADRRQIADALAAAYIGGHKPDFAALHEQRGVRLELPTY
MAB_0939|M.abscessus_ATCC_1997      --RAIVSLRKGVEDRRQIADALASAYVSGHRPNFAALQRHPRRTVELPTY
MSMEG_0408|M.smegmatis_MC2_155      --RAVASLRKGVADRRQIADALASAYVGGHRPDFAAVHRQPRRPVELPTY
Mvan_1003|M.vanbaalenii_PYR-1       --RAIPSLRKGPDARRQLAEAVAAAYIAGHRLDFTGHDGGPHRRLPLPTY
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           PVATASALRKDRPEPVSLVSALAGVFVAGTAVDWRAVVGQS-HFVELPTY
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          PFQRRRFWPKSAGMAIDGR---VGASAGSGILGSGKDLASGDSVYTSRLS
MAB_0939|M.abscessus_ATCC_1997      PFQRRRFWPKSSGTAIEG-----GGGLPSGILGRGEDLASGDSVYISRLS
MSMEG_0408|M.smegmatis_MC2_155      PFQRRRFWPKASSIAVDG------GTAASGILGSGKDLASGDTIYTSRLS
Mvan_1003|M.vanbaalenii_PYR-1       PFQHRSYWPKTAGIRSDG-------SSGSGLLGSAQDLASGDIVHTSRLS
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           AFERRRFWLSGDAVPADAAGLGLQAGEHALLGAVVELPASGGVVLTGRLS
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          VKTQPWLSDHVIYGTVVVPGATYAAMALAAVGTPAHAKDVFFYEPIILPE
MAB_0939|M.abscessus_ATCC_1997      VRSQPWLSDHVIYGTVVVPGATYAAMALAAVGTPARAKDVFFYEPIILPE
MSMEG_0408|M.smegmatis_MC2_155      VKSQPWLADHVIYGTVVVPGATYAAMALAAVGTPARLKDVFFYEPIILPE
Mvan_1003|M.vanbaalenii_PYR-1       VKTQPWLSDHVIYGTVVVPGATYAAMALAAMPTPARVQEVFFYEPIILGD
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           LAAQGWLADHAVGGVVIFPGAGFVELAIRAGDEVGCRVVDELTLAAPLVL
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          KSSREVQLTVHPSVDGE-SKFQVHSRPYGERGAEWALNAEGVVASGVGD-
MAB_0939|M.abscessus_ATCC_1997      KSSREVQLTLHPLEDGSGSKFQVHSRPYGERDVDWSLNAEGTVVTGIGDD
MSMEG_0408|M.smegmatis_MC2_155      KASREVQLTLHPADGGSVLSFQIHSRPYGERGADWSLNAEGTVDTAGSD-
Mvan_1003|M.vanbaalenii_PYR-1       KDSREVQLMLHRTDDADGWTFEVHSRPYGDRDADWSRNASGTVAAGVGD-
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           PSGGSVAVQVVVGSPDDSGARAVSVYSRGDAGSDWVLHAEGSLGSGSPEP
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          --SPAAAGDLEDPVDEAIERLNRMRPQELFETFADLELAWGPTWSGSLKS
MAB_0939|M.abscessus_ATCC_1997      AEPAPEAAEPAEPVDAAIERMERMRPMELFEIFADLELAWGPTWSGSLKS
MSMEG_0408|M.smegmatis_MC2_155      --PDAAADEQSDPVDEVIERLERMRPQDLFETFADLELAWGPTWSGSLKS
Mvan_1003|M.vanbaalenii_PYR-1       ----AAPDAAADPVDNAIERLTRTRPQQLFDAFADNDLAWGPAWCSSLRS
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           A---------TDLSTWPPVGAVEVENADGYQQLAERGYGYGPAFR-GLNA
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          LWLGEGEAIGDILVGAELAEQLGTEPMHPVLMDLCTGVAFPAFPALLAAE
MAB_0939|M.abscessus_ATCC_1997      LWLGEGEAIGDVLVGEELAEQLGTEPMHPVLMDLCTGVAFPAFPALLAAE
MSMEG_0408|M.smegmatis_MC2_155      LWLGDGEAVGDILVGAELAEQLGSEPMHPVLMDLCTGVAFPAFPALLAAE
Mvan_1003|M.vanbaalenii_PYR-1       LWVGTGEAVGDIAVGAELGEHLGREPIHPVLLDLCTGIAGAALLAAAAQT
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           MWRRGDEVFAEVALPADAGVSVSGFGIHPVMLDAALHAVILASDGADDFG
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          QGVNDLYLPLRYGQVSLQEKMPRRFYCRATWHEAPLDSETQVFDLEYLDR
MAB_0939|M.abscessus_ATCC_1997      QGVNDLFLPLRYGQVTLKEKMPRRFYCRARWHESPLDSETQVFDLDYLDR
MSMEG_0408|M.smegmatis_MC2_155      QGVNDLFLPLRYGQVTLAEKMPRRFYCRARWHRSALDSETQVFELEFVDL
Mvan_1003|M.vanbaalenii_PYR-1       DADPELFLPLRYGRVEVRERMPRRFYCRARWQTGGIDSETQVFDLDFLDH
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           VPEGSVLVPFAWQGVTLHAAGASAVRARI------APAGPSAVSIELSDG
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          DGRHLGGVREFTVKRAPREALLRGLGGDATRLLYTLGWHEVPVP----ES
MAB_0939|M.abscessus_ATCC_1997      DGRHLGGIREFTVKRAPREALLRGLGGDATRLLYTLGWHEVAVPPVAGEG
MSMEG_0408|M.smegmatis_MC2_155      GGRALGGIREFTVKRAPREALLRGLGGDATRLLYTLGWHEVPPP------
Mvan_1003|M.vanbaalenii_PYR-1       DGRNLGGIREFTVKRAPREALLRGLGADATRLIYRVGWRETSPP---VRD
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           LGLPVLSVASMLARPVTDQQLRAAVSGAGPDRLFGVDWTAQPSA------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          GDGAAPQGTWLIGGFDELAVSVPGCIPADR----------------TNPE
MAB_0939|M.abscessus_ATCC_1997      EESAASIGTWLIAGFDELAAKVPGCIPLNRE---------------TDPE
MSMEG_0408|M.smegmatis_MC2_155      PSADDAVGTWLIAGFDELAAKVPGCVPIDRN---------------TDLQ
Mvan_1003|M.vanbaalenii_PYR-1       DGALGPSSTWLVAGLDALADDVPGSIRIGFDRIWDPDRDGRVVLDPADDE
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           --ELQPVPVRIWGTVESEGDDDPGASVVFES-------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          SLRQLLTDAHGRGLPFSGVVWRAARSDGDES--DAEVAARLEAEIAELLG
MAB_0939|M.abscessus_ATCC_1997      LLGEVLVAAKERGVPFSGVVWRAAGPGATES--TTESAARLEGEIAHLLS
MSMEG_0408|M.smegmatis_MC2_155      VLGEVLSQAHARGAGFSGVVWRCATPGRKESGSASAESARLEAEITNLLS
Mvan_1003|M.vanbaalenii_PYR-1       HWRRLFALADERRAPVAGVVLGVTGRARPEE-PSADFAARLEAQIRDVLG
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           ------------------------------VPQAGEVVAGVYAATAAVLE
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          AVHTVQ---GGEVKLPGGLWIVTERAVATESGEPVDPVQAALWGFGRTAI
MAB_0939|M.abscessus_ATCC_1997      AVHTVQNSAQNGVKLPGGLWIVTERAVATESGEPVDPVQAALWGFGRTTI
MSMEG_0408|M.smegmatis_MC2_155      AVHAAQ---GPSVKLPGGLWIVTEHGVACESGEPVDPVQAALWGFGRTTI
Mvan_1003|M.vanbaalenii_PYR-1       AVHSLS---ALGAKPAAGLWIVTERAVAAEAGEPVDPVQSALWGLGRTLI
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           VLRSWL-----SRDGAGQLIITTRGAVALPDEDVTDLAGSAVWGLVRSAQ
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          NEEPALRCRLVDCDGSPQAVQALAALLSTP-VDEPELAVRQGKLLASRLL
MAB_0939|M.abscessus_ATCC_1997      NEEPALRAKLVDGDGSPEAVQALARLLVTP-VDEPEIAVRQGKLLASRLL
MSMEG_0408|M.smegmatis_MC2_155      NEEPALHCRLVDCDGSSEAVDLLAALLAAPGIQEPEIAVRQGKLLASRLL
Mvan_1003|M.vanbaalenii_PYR-1       AEEPGLRCLLVDLDGSEDAGPALARLLGAP-GDEPELALRQGRLLVPRLL
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           TEHPGRIVLVDTDAQLDEHAVAAVLAAGEPQVLWRNGEVYTARVHGSRAV
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          PWSRSGHLTVPRGGDYVLAPTERGAIDNLRLTDSEVP--PPAEGYVQVRV
MAB_0939|M.abscessus_ATCC_1997      PWSRTGHLTVPRGSDYVLAPTERGAIDNLRITEKEVP--APDEGYVQVRV
MSMEG_0408|M.smegmatis_MC2_155      PWARSGHLTLPRGGDFVLAPTERGAIDNLRLTETDVP--EPDEGYVQVRV
Mvan_1003|M.vanbaalenii_PYR-1       PWSRSGQLAIPRGTDYVLAPTERGVLDNLRVSETEVT--APPEGHVQVRV
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           ----AGLLVPPGDGPWRLGMSTAGTFENLRLEPIPDADAALQPGHVRVAL
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          EAAGLNFRDVLNVLGLYPGDPGPIGGDFAGTVTQLGEGVTGLDVGQRVYG
MAB_0939|M.abscessus_ATCC_1997      EAAGLNFRDVLNVLGLYPGDPGPIGGDFAGIVTQLGEGVTGVEVGQRVYG
MSMEG_0408|M.smegmatis_MC2_155      EAAGLNFRDVLNVLGLYPGDPGPIGGDFAGTVTQLGAGVSGLEIGQRVYG
Mvan_1003|M.vanbaalenii_PYR-1       EAAGLNFRDVLNALGLYPGDPGPIGGELAGVVTAPGPDVDGFDVGQRVFG
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           SAMAANFRDVMIALGLYPDPDAAMGVEGAGVVVETASPDGRFAVGDRVVG
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          SMQGAFASRFNVPGQFLAPIPDGVSAVEAATIPAAALTVR-LSFDWAQVK
MAB_0939|M.abscessus_ATCC_1997      SMQGAFGSRFNVPAQFLAPIPDGISGVEAATIPAAALTVR-LSFDWAQLK
MSMEG_0408|M.smegmatis_MC2_155      SMQGAFASRFNVPAQFLAPIPDGIGAVEAATIPAAALTVR-LAFDWAQLK
Mvan_1003|M.vanbaalenii_PYR-1       FAVGAFASRVNVPVQFLAPVPEGISAVAAATTPAAVLTAG-LAFDWAALR
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           LFPEGTGTIAITDHRLLVKIPAGWSDTAAATTSVVFATAFYALRDLASVQ
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          SGDKVLIHAASGGVGLAAVQMAQQCGAEVYATASTFKRATLRKLG--VKH
MAB_0939|M.abscessus_ATCC_1997      PGDKVLIHAASGGVGLAAIQMAQQFGAEVFATASTFKRATLRKLG--VKY
MSMEG_0408|M.smegmatis_MC2_155      PGDKVLIHAASGGVGLAAIQMAQQSGAEVFATASTFKRSTLRRLG--VKY
Mvan_1003|M.vanbaalenii_PYR-1       AGDRVLIHAASGGVGLAAVQLARQRGATVFATASGYKRPMLRAMG--VDH
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           PGQRILVHAATGGVGMAAVQLARHWGLEVFATASKGKWDTLRAMGFDEDH
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          VYDSRTTDFAEQILADTDGAGVDVVLNSLTSEGFIEATLRATAQHGRFAE
MAB_0939|M.abscessus_ATCC_1997      VYDSRTTDFADQILADTDGAGVDVVLNSLTSEGFIEATLRATAKNGRFAE
MSMEG_0408|M.smegmatis_MC2_155      VYDSRTTDFADQILADTNGAGVDVVLNSLTSAGFVEATLKATAQGGRFAE
Mvan_1003|M.vanbaalenii_PYR-1       VYDSRTTDFADQILADTDGAGVDVVLNSLTNDGFVAATVRATARNGRFAE
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           IGDSRSLEFEDKFRAATGGRGMDVVLDSLAGE-FVDASLRLVAPGGVFLE
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          IAKRDIWTVEQMAAARPDLAYEIVALDTVMFTEPDRIRDLLTEVSAGLRD
MAB_0939|M.abscessus_ATCC_1997      IAKRDIWTTEQMAQSRPDIAYEIVALDTVMFQEPDRIRVLLTEVSEGLAK
MSMEG_0408|M.smegmatis_MC2_155      IAKRDIWSHEQMAEARPDIAYEIVALDTVMFTEPDRIRDLLTEVSDGMAR
Mvan_1003|M.vanbaalenii_PYR-1       IAKRDIWSPEQMAAARPDIDYEVLALDAVMQQDPDRIQLLLADLADSLAR
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           MGKTDIREAAVVAQQHTGVRYRAFDLFEAG---PDHIAQILAELAALFSE
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          GAWTPLPAEVYPLTEARAAFRRMQQARHIGKIVVQIPNPLQPQPDRSYLI
MAB_0939|M.abscessus_ATCC_1997      GEWTPLPAEIYPLTEARTAFRRMQQARHIGKIVCQMPNPLAPRPDRTYLI
MSMEG_0408|M.smegmatis_MC2_155      GEWTPLPAEIYPITEARSAFRRMQQARHIGKIVLQVPKPLQPQQDRSYLI
Mvan_1003|M.vanbaalenii_PYR-1       GETAPLPFEAYPLAEATTAFRRMQQARHTGKIILQMPKPLQPHGDRSYLI
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           DVLRPLPVTTFDVRRAPAALRYLSQARHVGKVVLTMPDAWAAG---TVLI
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          TGGLGAIG-LHTAGYLAQLGAGDIVLTSRRAPDAAAQQAIADIADRTKAR
MAB_0939|M.abscessus_ATCC_1997      TGGLGAIG-LHTAAYLAQLGAGDIVLTSRRAPDTDAQRVIGEITERSKTR
MSMEG_0408|M.smegmatis_MC2_155      TGGLGAIG-LHTAAYLAQLGAGDIVLTSRRDPDESAQRAIDEITERHKCR
Mvan_1003|M.vanbaalenii_PYR-1       TGGLGALG-LHAAAYLAQLGAGDIVLTGRRMPDAATERAISEIAERYHCR
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           TGGTGMAGSALARHVVAHHGVRQLVLVSRRGPDAPGAAELAEELSAFGAQ
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          LHVFTADVGVEADVAALLERIRAELPPLAGVAHLAGVLDDALLSQQSVER
MAB_0939|M.abscessus_ATCC_1997      IHVFTADVGAESEVAGLLERIRAELPPLAGVAHLAGVLDDALLGQQSVER
MSMEG_0408|M.smegmatis_MC2_155      IHTYAADVGDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPER
Mvan_1003|M.vanbaalenii_PYR-1       IHTFAADVGDESAVRDLLERIRTELPPLAGVAHLAGVLDDALLPQQSPER
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           VQVVACDAADRAALAKLIADIPMQHP-LSAVIHTAGALDDAVVTSLTPER
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          FRTALAPKAFGAVHLDRLTRVDDLDFFLVSSSVSSLFGSPGQSNYATANA
MAB_0939|M.abscessus_ATCC_1997      FRTTLAPKAFGAEYLDRLTKGDDLDFFIVSSSVSSLFGSPGQSNYATANA
MSMEG_0408|M.smegmatis_MC2_155      FRTTLAPKAYGASHLDRLTRDDDLDFFIVSSSVSSLFGSPGQANYATANA
Mvan_1003|M.vanbaalenii_PYR-1       FRTTLAPKAFGAWHLHRLTRDTELEFFIVYSSGSSVLGSPGQANYATANA
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           IETVLRAKVDAAWNLHELTRDMDLSAFVMFSSMAGLVGSSGQGNYAAANS
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          FLDGLVAQRRAQGLPATGVNFGPWARGGMASSEAAAANISAQG-------
MAB_0939|M.abscessus_ATCC_1997      LLDGLIAQRRAQGLPATGINFGPWGQGGMASSEAATANISAQG-------
MSMEG_0408|M.smegmatis_MC2_155      MLDGLVAKRRAQGLVATGINFGPWGQGGMASSEAATANITAQG-------
Mvan_1003|M.vanbaalenii_PYR-1       VLDGLVAHRKARGLPATGVNWGPWAQGGMATSDAARANLGAQG-------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           FLDGLAVHRQAHGLPAISLGWGLWDQASNMTGGLAAVDFKRFARDGIVAM
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          -----LIPLEPSAALTAMAEVVANGTAQATVLKANWQRAAKVLGSSRPPI
MAB_0939|M.abscessus_ATCC_1997      -----LIPLDPSAALAALAEVVANGTGQATILKANWQRAAKVLGSSRPPI
MSMEG_0408|M.smegmatis_MC2_155      -----LIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSARPPI
Mvan_1003|M.vanbaalenii_PYR-1       -----LIPLEPTAALNALGEIVAHGIASAVVLKANWQRAAKLLGATRPPI
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           SSDEALGLLDTAMVLGEPFMLPAHIDFAALRVKFDGGTLPPMFVDLINAP
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          LDLVLPSAVGEITGDSELLKQLQEIPVPQRAGFVTEFLQKEVQNFLRLAQ
MAB_0939|M.abscessus_ATCC_1997      LDLVLPSAVGEVTGDSELLKQLMEIPVPQRAGFVTEFLQREVQNFLRLAQ
MSMEG_0408|M.smegmatis_MC2_155      LDLVLPSAAGEATGDSELLKQLMEIPIPQRAGFVTEFLQREVQNFLRLAS
Mvan_1003|M.vanbaalenii_PYR-1       LDHVLPSAVAAGPGDSALLKQLQDVPEAQRGSFVTEHLQRELQQILGLAQ
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           TRRQVDDSLAAAKSKSALLQRLEGLPEDEQHAILLNLVRSHIATVLGNSS
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          PP--AATSRFLDLGTDSLMAIELRNRLHSQFGGAFTINATAVFDYPTIGG
MAB_0939|M.abscessus_ATCC_1997      PP--AATSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGG
MSMEG_0408|M.smegmatis_MC2_155      PP--AASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGG
Mvan_1003|M.vanbaalenii_PYR-1       PP--AATGRFLELGMDSLMAVELRNRLVGQFGSGFTITATAVFDYPTIGA
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           PDAIDPDRAFQELGFDSLTAVEMRNRLKSATG--LALSPTLIFDYPNSAA
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          LAEYLVAQLPDAETPQAAP-------QSESEPGPDVTE------------
MAB_0939|M.abscessus_ATCC_1997      LAEYLVGQLPDADAESAEAPPAVESAEAESGAGPAAASDAVSELKE----
MSMEG_0408|M.smegmatis_MC2_155      LAEYLVGQLPDAEAPETA--------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       LAEYLAAQTPESTEEGTEMKTADPDGQPATVGHADVVLQTS---------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           LAGYMHRELVGASPQSDTTAEAPGEAELQRVVASIPVKRLRQAGVLELLL
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          -----------------------------------------
MAB_0939|M.abscessus_ATCC_1997      -----------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      -----------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       -----------------------------------------
Rv1661|M.tuberculosis_H37Rv         -----------------------------------------
Mb1689|M.bovis_AF2122/97            -----------------------------------------
MMAR_2471|M.marinum_M               -----------------------------------------
MAV_3109|M.avium_104                -----------------------------------------
MUL_2266|M.ulcerans_Agy99           ALANETGGNGQAAVTAETSEEDLADMDLDALVNAAFMNDDE
MLBr_00135|M.leprae_Br4923          -----------------------------------------
TH_4621|M.thermoresistible__bu      -----------------------------------------