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MSGTTTHVDYLKRLTADLRRTRRRLSDLEAKLSEPVAVVGMGCRYPGGVDSPETLWELVAQGRDAVSDFP ADRGWDVDGLFDPDPDACGKMYTRRGTFLEHAGDFDAGFFGIGPSEALAMDPQQRLLLEVSWEALERTGI DPTKLRGSATGVFAGVIHAGYGGQLSGELEGYGLTGSTLSVASGRVAYVLGLEGPAVSVDTACSSSLVAL HLAVQSLRSGECDLALAGGVTVMATPAAFVEFSRQRALARDGRCKVYAGAADGTAWSEGAGVLVVERLVD ARRLGHPVLALVRGSAVNQDGASNGLTAPNGPSQQRVIRAALASARLRAVEVDVVEGHGTGTMLGDPIEA QALLATYGQDRVEPLWLGSIKSNIGHTSAAAGVAGVIKMVQAMRHGVMPKTLHVDVPTPHVDWSVGAVSL LTQPRAWSVHGRPRRAGVSSFGISGTNAHVILEQAPVVESVVPEVASPTAASAVPWVLSARSEQALAGQA QRLLAFVAANPDLDPIDVGWSLVKTRAMFEHRAVVVGADRGALLAGLAALAAGESGAGVAVGRARSVGKT VFVFPGQGAQWVGMGAQLYAELPLFALAFDAVAEELDRHLRLPLRNVLWEGDEALLTSTEFAQPALFAIE VALATLLQHWGISPDFLIGHSVGEIAAAHLAGVLSLTDAAGLVAARGRLMAELPAGGVMVVVAASEEEVL PVLVDGANLAAVNAPHSVVVSGCEAAVSDIADHFARRGRRVHRLAVSHAFHSLLMEPMLAEFTRIAAGIS VSKPRIPLVSNVTGQMAGAGYGDGQYWVEHARRPVRFAEGVQLLNAVGATRFVEVGPGGGLTALVEQSLP LGEALSVAMMRREHPEVSSVLGAVATLFTAGAQMDWPAVFGSPGRRIELPTYAFQRQRYWLPPTSAGSAD ISGVGLLAARHGLLGAVVEQPDSDVVVLTGRLSVGEQRWLADHVIAGVVLLAGAAFVELALRAADQVDCG VVEELTVVTPLVLPTVGGVQLQVVVGVGEMGQRPVSIYSRNAESDSGWVLHARGVLGAKAVAPAADLSVW PPLGAAPVDVDGAYQRFAELGYEYGRAFQGLTAMWRRESELFADVAVPDDVDVTLSGFGIHPLVLDAALH AMGMVGEQAATMLPFSWQGVSLHAAGASRVRARIAPAGDGTVSVELADQAGLPVLSVQALVMRSVSSQLL SAAVAAADAAGRGLLEVAWLPVELAHNDISADLVVWELESFQDGVGPVYSATHRVLVALQSWLAQERAGR LVVLTQGSVGQDATNLAGAAVWGLVRSAQAEHPGRVMLVDSDGSMDVGDVIGCGEEQLMIRNGTAYAARL AQLRPQPILQLPDTNSGWRLVAGGAGALEDLTLASCPAKELAPGQVRIEVRALGVNFRDVLVALGIYPGA AELGAEGAGVVTEVGPGVTGLAVGDPVMGLLGVAGSEAVVDARLVVKLPNRWPLTDAAGVPVVFLTAYYA LRVLAQVQPGESVLVHAAAGGVGMAAVQLARLWGLEVFATASRGKWDTLHTMGCDNTHVADSRTLAFEET FWLTTEGRGVDVVLNSLAGEFTDASLRLLPRGGRFIEMGKTEFGTPRSLPRTILGWPTGLST
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1662 | pks8 | - | 100% (1602) | Probable polyketide synthase pks8 |
| M. tuberculosis H37Rv | Rv1661 | pks7 | 0.0 | 61.85% (1612) | polyketide synthase pks7 |
| M. tuberculosis H37Rv | Rv2048c | pks12 | 0.0 | 59.43% (1607) | polyketide synthase pks12 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1690 | pks8 | 0.0 | 99.69% (1602) | polyketide synthase pks8 |
| M. gilvum PYR-GCK | Mflv_0405 | - | 0.0 | 42.46% (1121) | beta-ketoacyl synthase |
| M. leprae Br4923 | MLBr_00135 | - | 0.0 | 61.29% (1617) | putative polyketide synthase |
| M. abscessus ATCC 19977 | MAB_0939 | - | 0.0 | 38.24% (1692) | polyketide synthase |
| M. marinum M | MMAR_2472 | pks8 | 0.0 | 67.96% (1598) | polyketide synthase, Pks8 |
| M. avium 104 | MAV_3108 | - | 0.0 | 68.24% (1606) | erythronolide synthase, modules 3 and 4 |
| M. smegmatis MC2 155 | MSMEG_0408 | - | 0.0 | 42.79% (1131) | type I modular polyketide synthase |
| M. thermoresistible (build 8) | TH_4621 | - | 0.0 | 36.99% (1657) | PUTATIVE mycocerosic acid synthase |
| M. ulcerans Agy99 | MUL_2005 | pks15/1 | 0.0 | 62.36% (1618) | polyketide synthase Pks15/1 |
| M. vanbaalenii PYR-1 | Mvan_0269 | - | 0.0 | 42.66% (1111) | beta-ketoacyl synthase |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_0939|M.abscessus_ATCC_1997 MDSAENPIESTPRFAIIGYAARFPGAADAEEFWDVLREGRDAISEVPADR
Mvan_0269|M.vanbaalenii_PYR-1 MGSAEHPNGPAPRFAIVGYAARFPGAPDADAFWDVLREGRDAISDVPRDR
Mflv_0405|M.gilvum_PYR-GCK MGSAAHQGESAHRFAIVGYAGRFPGARDAESFWELLADGRDAISEVPEDR
MSMEG_0408|M.smegmatis_MC2_155 MVSAEHPIEPTPSFAIIGYAARFPGAASAEEYWALLRDGREAISDVPKDR
Rv1662|M.tuberculosis_H37Rv --------------------------------------------------
Mb1690|M.bovis_AF2122/97 --------------------------------------------------
MMAR_2472|M.marinum_M --------------------------------------------------
MAV_3108|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MUL_2005|M.ulcerans_Agy99 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 WDAEEFFDPEPGAPGKVVTRRAGFVEDVTGFDAPFFGMSTREVRLMDPQH
Mvan_0269|M.vanbaalenii_PYR-1 WDAEEFFDPEPGAPGKVVTRRAGFVDDVTGFDAPFFGMSTREVRMMDPQH
Mflv_0405|M.gilvum_PYR-GCK WDVEAFFDPDPSTPGKVVTRRAGFVDDVSGFDAPFFGMSTREVRLMDPQH
MSMEG_0408|M.smegmatis_MC2_155 WDIEEFFDPDPSTPGKVVTRRAGFVDDVTGFDAPFFGMSAREVRLMDPQH
Rv1662|M.tuberculosis_H37Rv --------------------------------------------------
Mb1690|M.bovis_AF2122/97 --------------------------------------------------
MMAR_2472|M.marinum_M --------------------------------------------------
MAV_3108|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MUL_2005|M.ulcerans_Agy99 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 RLLLETAWRAVEHSGIAPTDLAETNSGVFVGLATHDYLGMASDELTFPEI
Mvan_0269|M.vanbaalenii_PYR-1 RLLLETAWRAVEHSGTAPTALAGSNTGVFVGLATHDYLGMASDELTYPEI
Mflv_0405|M.gilvum_PYR-GCK RLLLETAWRAIEHSGTAPSELANTNTGVFVGLATHDYLGMASDELSYPEI
MSMEG_0408|M.smegmatis_MC2_155 RILMETAWRAVEHSGIAPTSLANSNTGVFVGLATHDYLGMASDELTYPEI
Rv1662|M.tuberculosis_H37Rv --------------------------------------------------
Mb1690|M.bovis_AF2122/97 --------------------------------------------------
MMAR_2472|M.marinum_M --------------------------------------------------
MAV_3108|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MUL_2005|M.ulcerans_Agy99 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 EAYMAIGTSNAAAAGRISYRLGLQGPSVAVDTACSSSLVAIHQACQALQL
Mvan_0269|M.vanbaalenii_PYR-1 EAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAIHQACQALRL
Mflv_0405|M.gilvum_PYR-GCK EAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAIHQACQALRL
MSMEG_0408|M.smegmatis_MC2_155 EAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAIHQACQALRL
Rv1662|M.tuberculosis_H37Rv --------------------------------------------------
Mb1690|M.bovis_AF2122/97 --------------------------------------------------
MMAR_2472|M.marinum_M --------------------------------------------------
MAV_3108|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MUL_2005|M.ulcerans_Agy99 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 GECDLALAGGANVLLTPATMITFSHAHMLAPDGKCKTFDAAADGYVRGEG
Mvan_0269|M.vanbaalenii_PYR-1 GECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEG
Mflv_0405|M.gilvum_PYR-GCK GECDLALAGGANVILTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEG
MSMEG_0408|M.smegmatis_MC2_155 NECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEG
Rv1662|M.tuberculosis_H37Rv --------------------------------------------------
Mb1690|M.bovis_AF2122/97 --------------------------------------------------
MMAR_2472|M.marinum_M --------------------------------------------------
MAV_3108|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MUL_2005|M.ulcerans_Agy99 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 SGVIVIKRLEDAIRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIA
Mvan_0269|M.vanbaalenii_PYR-1 CGVIVIKRLEDAVRDGDRIRAVIRGSSINQDGASGGLTVPNGVAQQRVIA
Mflv_0405|M.gilvum_PYR-GCK CGVIVIKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIG
MSMEG_0408|M.smegmatis_MC2_155 CGVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIA
Rv1662|M.tuberculosis_H37Rv --------------------------------------------------
Mb1690|M.bovis_AF2122/97 --------------------------------------------------
MMAR_2472|M.marinum_M --------------------------------------------------
MAV_3108|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MUL_2005|M.ulcerans_Agy99 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 DALKRAGVAPSEVGYLEAHGTGTSLGDPIEAQAAGAAYGIGRETNDPLLI
Mvan_0269|M.vanbaalenii_PYR-1 DALKRSDLEPKDVGYLEAHGTGTSLGDPIEAQAAGAVLGAGREPSRPLLI
Mflv_0405|M.gilvum_PYR-GCK DALSRAGLAPGDVDYLEAHGTGTSLGDPIEAQAAGAALGPGREPQRPLLI
MSMEG_0408|M.smegmatis_MC2_155 DALKRAGLRPADVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLI
Rv1662|M.tuberculosis_H37Rv --------------------------------------------------
Mb1690|M.bovis_AF2122/97 --------------------------------------------------
MMAR_2472|M.marinum_M --------------------------------------------------
MAV_3108|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MUL_2005|M.ulcerans_Agy99 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 GSAKTNIGHLEAAAGIAGVIKVILSLENELLPQHRNFQNPSPHIPWDRLP
Mvan_0269|M.vanbaalenii_PYR-1 GSAKTNIGHLEAAAGIAGVIKVILSLEHRTLPKHLNFENPSPHIPWDRLA
Mflv_0405|M.gilvum_PYR-GCK GSAKTNIGHLEAAAGIAGVIKVVLSLEHETLPKHLNFENPSPHIPWDRLP
MSMEG_0408|M.smegmatis_MC2_155 GSAKTNIGHLEAAAGIAGVIKVVMALENETLPKHLNFETPSPHIPWERLP
Rv1662|M.tuberculosis_H37Rv --------------------------------------------------
Mb1690|M.bovis_AF2122/97 --------------------------------------------------
MMAR_2472|M.marinum_M --------------------------------------------------
MAV_3108|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MUL_2005|M.ulcerans_Agy99 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 VEVVREARPWGRN---GRPRIAGVSSFGFAGTNAHVILEEAPVVSRDAVE
Mvan_0269|M.vanbaalenii_PYR-1 VEVVKETIPWERD---GGPRIAGVSSFGFAGTNAHVILEEAP--EQAAAP
Mflv_0405|M.gilvum_PYR-GCK VEVVKESIPWRRGQRGGRPRIAGVSSFGFAGTNAHVILEEAP---LAAEP
MSMEG_0408|M.smegmatis_MC2_155 IEVVRETVPWQRN---GKPRIAGVSSFGFAGTNAHVILEEAPAVGTPATT
Rv1662|M.tuberculosis_H37Rv --------------------------------------------------
Mb1690|M.bovis_AF2122/97 --------------------------------------------------
MMAR_2472|M.marinum_M --------------------------------------------------
MAV_3108|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MUL_2005|M.ulcerans_Agy99 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 PPAPAGGRKFSILPLSARTPAALAQLADKYRAWLNAHPEAALADLCFTAG
Mvan_0269|M.vanbaalenii_PYR-1 GPVQQPDRRFSLLPLSARTPAALTQLAGQYRDWWTAHPEATLADVCFTAG
Mflv_0405|M.gilvum_PYR-GCK AQESVDDGRFTLLPLSARTPAALMAVADRYRDWLVANPDATLADLCFTAG
MSMEG_0408|M.smegmatis_MC2_155 EPVE-DPRRYSVLPLSARTPEALVRLAGEYRDWLRAHPQARLADVSHTAG
Rv1662|M.tuberculosis_H37Rv --------------------------------------------------
Mb1690|M.bovis_AF2122/97 --------------------------------------------------
MMAR_2472|M.marinum_M --------------------------------------------------
MAV_3108|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MUL_2005|M.ulcerans_Agy99 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 VGRAHLEHRAALVVNTREAAVELLSAVADDRPAPGLGRGESHDTPKTAWL
Mvan_0269|M.vanbaalenii_PYR-1 AGRAHLEHRAALVVNSAESAVELLGALADDRPAPGLVRGESHDTPKTAWL
Mflv_0405|M.gilvum_PYR-GCK TARSHLEHRAALVVNTREAALDLLGALADDRPAPGLVRGESHDTPKTAWL
MSMEG_0408|M.smegmatis_MC2_155 TARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHEAPKTAWL
Rv1662|M.tuberculosis_H37Rv --------------------------------------------------
Mb1690|M.bovis_AF2122/97 --------------------------------------------------
MMAR_2472|M.marinum_M --------------------------------------------------
MAV_3108|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MUL_2005|M.ulcerans_Agy99 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 FTGQGSQYPGMARELFETEPVFADTLNRCAAAVADVLEKPLLDVIFDVD-
Mvan_0269|M.vanbaalenii_PYR-1 FTGQGSQYPGMARELYDTEPVFAETLNRCAEAVADVLEKPLLDVIFDAE-
Mflv_0405|M.gilvum_PYR-GCK FTGQGSQYPGMSRELFDTEPLFAETLRECAAAVDGMLEKPLLDVIFDTDG
MSMEG_0408|M.smegmatis_MC2_155 FTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDAD-
Rv1662|M.tuberculosis_H37Rv --------------------------------------------------
Mb1690|M.bovis_AF2122/97 --------------------------------------------------
MMAR_2472|M.marinum_M --------------------------------------------------
MAV_3108|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MUL_2005|M.ulcerans_Agy99 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 --GPEAEETLRQTSYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVGQYS
Mvan_0269|M.vanbaalenii_PYR-1 --ADDAEKTLQNTCYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVGQYS
Mflv_0405|M.gilvum_PYR-GCK VLDTDSNETLRHTSYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVGQYA
MSMEG_0408|M.smegmatis_MC2_155 ELDGDTESPLRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYS
Rv1662|M.tuberculosis_H37Rv --------------------------------------------------
Mb1690|M.bovis_AF2122/97 --------------------------------------------------
MMAR_2472|M.marinum_M --------------------------------------------------
MAV_3108|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MUL_2005|M.ulcerans_Agy99 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 AACVAEVFSLEDGARLIAERGRLFSSLPAGGRMAAVFTDAERAERLTDEF
Mvan_0269|M.vanbaalenii_PYR-1 AACVAGVFSLTDGARLMAERGRLFGSLPEGGRMVAVFTTAERAEAMTDEF
Mflv_0405|M.gilvum_PYR-GCK AACVAGVLSLRDGARLMAERGRLFGSLPSGGRMAAVFAAAERVEALTDEY
MSMEG_0408|M.smegmatis_MC2_155 AACVAGVFDVEDGARLIAERGRLFGSLPAGGRMAAVFTAPERAERLTDEY
Rv1662|M.tuberculosis_H37Rv --------------------------------------------------
Mb1690|M.bovis_AF2122/97 --------------------------------------------------
MMAR_2472|M.marinum_M --------------------------------------------------
MAV_3108|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MUL_2005|M.ulcerans_Agy99 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 PSLSVAAYNGANTVLSGPAQDLEKAIAALVADGVRCDFLETSHAFHSALL
Mvan_0269|M.vanbaalenii_PYR-1 PSLSVAAYNGTNTVLSGPAGDLEKAVATLSADGVRCDWLDTSHAFHSALL
Mflv_0405|M.gilvum_PYR-GCK PALSVAAYNGANTVLSGPATDLERAVAGLVADGVRCDWLETSHAFHSALL
MSMEG_0408|M.smegmatis_MC2_155 PSLSVAAYNGANTVLSGPAKDLESAVATLVADGVRCDWLDTSHAFHSALL
Rv1662|M.tuberculosis_H37Rv --------------------------------------------------
Mb1690|M.bovis_AF2122/97 --------------------------------------------------
MMAR_2472|M.marinum_M --------------------------------------------------
MAV_3108|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MUL_2005|M.ulcerans_Agy99 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 DPILDEFEAYANQFNYKTPQRILIDNRTGTALGRSVKLDGAYWRRHARQP
Mvan_0269|M.vanbaalenii_PYR-1 DPILDDFESYANQFDFAAPQRILIDNRTGTALGRSVQLDGTYWRRHARQP
Mflv_0405|M.gilvum_PYR-GCK DPILDDFESYARGITFTAPQRILIDNRTGAALGRSVTLDAAYWRRHARQP
MSMEG_0408|M.smegmatis_MC2_155 DPILDDFESFAQKLEYREPQRILIDNRTGSALGRSTRLDGAYWRRHARQP
Rv1662|M.tuberculosis_H37Rv --------------------------------------------------
Mb1690|M.bovis_AF2122/97 --------------------------------------------------
MMAR_2472|M.marinum_M --------------------------------------------------
MAV_3108|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MUL_2005|M.ulcerans_Agy99 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 VEFAKSVRTLADMNCKVLLEIGPQPVLTAAALRAWPDPATAPRAIASLRR
Mvan_0269|M.vanbaalenii_PYR-1 VEFAKSVRTLAEMNCKLLVEIGPRPVLTAAALGAWPDPATAPRVIASLRR
Mflv_0405|M.gilvum_PYR-GCK VEFAKSVHTLADMNCKLLVEIGPRPVLTAAALSAWPDPATSPRVIASLRR
MSMEG_0408|M.smegmatis_MC2_155 VEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATTPQVLASLRP
Rv1662|M.tuberculosis_H37Rv --------------------------------------------------
Mb1690|M.bovis_AF2122/97 --------------------------------------------------
MMAR_2472|M.marinum_M --------------------------------------------------
MAV_3108|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MUL_2005|M.ulcerans_Agy99 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 NTADHRQITEAAADAYVLGHLPDFGAFQHAPARKLDLPTYPFERRQYWFS
Mvan_0269|M.vanbaalenii_PYR-1 TAADHRQITEAVADAYVLGHLPEFGAFRDAGARKLDLPTYPFEHRQYWFR
Mflv_0405|M.gilvum_PYR-GCK TTADQRQITEAVADAYVLGHLPRFAAFRRDGARVLDLPTYPFEHRQYWFS
MSMEG_0408|M.smegmatis_MC2_155 TTADHRQITEAVAAAYAAGHLPDFRAFRQPDARKLDLPTYPFEHRQFWFS
Rv1662|M.tuberculosis_H37Rv --------------------------------------------------
Mb1690|M.bovis_AF2122/97 --------------------------------------------------
MMAR_2472|M.marinum_M --------------------------------------------------
MAV_3108|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MUL_2005|M.ulcerans_Agy99 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 DKRDGDNRDAGNRQQNNGGPRTEAVRLLEDGKIEELANLLGGVDGDQQTL
Mvan_0269|M.vanbaalenii_PYR-1 DNQDPD----GSEALQPRTPSTEAVRLLEDGRIEELATLLDGAAGDQQTL
Mflv_0405|M.gilvum_PYR-GCK DSREPV------AAAPQRGARTETVRLLEDGRIEELAALLGGTVDDPFTF
MSMEG_0408|M.smegmatis_MC2_155 DNRAIDRDTQTASAGSVTPHRTQAVRLLEDGQIEELAALIDGETVDEQTL
Rv1662|M.tuberculosis_H37Rv --------------------------------------------------
Mb1690|M.bovis_AF2122/97 --------------------------------------------------
MMAR_2472|M.marinum_M --------------------------------------------------
MAV_3108|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MUL_2005|M.ulcerans_Agy99 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 NVLTKLAAQHNLQRTTQTIADDRYQFRWEKSPTPLSGSQAAGGVTWLLVA
Mvan_0269|M.vanbaalenii_PYR-1 DVLSRLAAQHNQQRSSQSITNDRYEIRWEQSAAALSGAETDEVSSWILVG
Mflv_0405|M.gilvum_PYR-GCK DVLNRLAAQHNQQRSTESIADDRYQIRWETAAEPPVGADAADGITWLLVG
MSMEG_0408|M.smegmatis_MC2_155 RVLNKLAARHNQQRSTHVDPDARYEIRWDAIAS--AAASTGAAADWILVG
Rv1662|M.tuberculosis_H37Rv --------------------------------------------------
Mb1690|M.bovis_AF2122/97 --------------------------------------------------
MMAR_2472|M.marinum_M --------------------------------------------------
MAV_3108|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MUL_2005|M.ulcerans_Agy99 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 DAAGAAQPLLDVLTARGQQHRVLALPVSDADEAELVEALRSAADEDSALR
Mvan_0269|M.vanbaalenii_PYR-1 DDTEATRPLVDVLSARGQRYRIFGLPVSDADEEQLGEALRLAAAEDSTLR
Mflv_0405|M.gilvum_PYR-GCK DDTDATRPLVDVLAARGHRYRILGLPKSGAEEHELADTLRDAAADATDLR
MSMEG_0408|M.smegmatis_MC2_155 DDTAAVLEFADALTAGGHRHQIVALPGSDADEAQLVDTLRAASAG--ELY
Rv1662|M.tuberculosis_H37Rv --------------------------------------------------
Mb1690|M.bovis_AF2122/97 --------------------------------------------------
MMAR_2472|M.marinum_M --------------------------------------------------
MAV_3108|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MUL_2005|M.ulcerans_Agy99 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 IVHVAALAGQ----GSSSAQSLLRIQHQVLGGTRRLFRAAAAAELRAPIW
Mvan_0269|M.vanbaalenii_PYR-1 IVHVGGLDSDPDPGTAPSMRSLLRMQHRILGGTRRLFRAAAAAELRTPIW
Mflv_0405|M.gilvum_PYR-GCK IVHVAALDAA---ESDTSMKSLLRMQHRVLGGTRRLFGAAVAAQLRSPMW
MSMEG_0408|M.smegmatis_MC2_155 VVHIAAGDGA-----AAPMRDLLRVQHRTLGGLRRLFRAANDAELRSPIW
Rv1662|M.tuberculosis_H37Rv --------------------------------------------------
Mb1690|M.bovis_AF2122/97 --------------------------------------------------
MMAR_2472|M.marinum_M --------------------------------------------------
MAV_3108|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MUL_2005|M.ulcerans_Agy99 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 IVTRGAQHVIEGDTVAPEQSALWGFGRAAALELPQVWGGLADLSDAGTDE
Mvan_0269|M.vanbaalenii_PYR-1 VVTRRAQHVTATDTVAPDQSCLWGFGRAAALELPQLWGGLADLADGTADE
Mflv_0405|M.gilvum_PYR-GCK LVTRGAQHVTDTDVVAPDQTCLWGFGRAASLEHPQIWGGLADLGGGTSDE
MSMEG_0408|M.smegmatis_MC2_155 LVTRDGQRVTDTDTVVPEQSCLWGFGRAAALELPHIWGGLADLSG-ADTE
Rv1662|M.tuberculosis_H37Rv --------------------------------------------------
Mb1690|M.bovis_AF2122/97 --------------------------------------------------
MMAR_2472|M.marinum_M --------------------------------------------------
MAV_3108|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MUL_2005|M.ulcerans_Agy99 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 WAQFIGRVSVSGEASTREDQLALRGQAVHVPRLVRREELPSGKPLEVRSD
Mvan_0269|M.vanbaalenii_PYR-1 WSRLLNRITAPHGPAVREDQIALRDHAVYVPRLVRRAGRPAGKPLQLRDD
Mflv_0405|M.gilvum_PYR-GCK WSRLLNRIAATHDPAVMEDQVAVRGSTSYVPRLVHRDTLPSGKPLHLRAD
MSMEG_0408|M.smegmatis_MC2_155 WPRLIARITSPRD---GEDQIALRGDAVYAPRLVRRTGEPSDTPLPVRED
Rv1662|M.tuberculosis_H37Rv --------------------------------------------------
Mb1690|M.bovis_AF2122/97 --------------------------------------------------
MMAR_2472|M.marinum_M --------------------------------------------------
MAV_3108|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MUL_2005|M.ulcerans_Agy99 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 ATYLVTGGLGSIGLEIAGYLAGRGAKHLVLTSRREPGEAARQRIDALAAQ
Mvan_0269|M.vanbaalenii_PYR-1 ATYLVTGGLGSIGLEIAGYLAAHGARHLVLTSRRAPGDATQQRIDALGAQ
Mflv_0405|M.gilvum_PYR-GCK ATYLVTGGLGSLGLEIAGYLAANGAGHLVLTSRRTPDEAAASRIEALRER
MSMEG_0408|M.smegmatis_MC2_155 RTYLVTGGLGAIGLEVAGYLASHGAGHVVLTSRREPGDDARRRLDGLREQ
Rv1662|M.tuberculosis_H37Rv --------------------------------------------------
Mb1690|M.bovis_AF2122/97 --------------------------------------------------
MMAR_2472|M.marinum_M --------------------------------------------------
MAV_3108|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MUL_2005|M.ulcerans_Agy99 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 G-CEVRAVTADVADGHDVARLLAGIQAELPPLAGIVHAAGEIGTTPLSDL
Mvan_0269|M.vanbaalenii_PYR-1 HSCQIRVVAADVADAHDVARLLAAVAAELPPLAGIVHAAGEIGTTPLVSL
Mflv_0405|M.gilvum_PYR-GCK HGCEVRVVTADVADAHAVARLLATVQAEMPPLAGIVHAAGEIGTTPLADL
MSMEG_0408|M.smegmatis_MC2_155 YACDVRVITADVADAHDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGL
Rv1662|M.tuberculosis_H37Rv --------------------------------------------------
Mb1690|M.bovis_AF2122/97 --------------------------------------------------
MMAR_2472|M.marinum_M --------------------------------------------------
MAV_3108|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MUL_2005|M.ulcerans_Agy99 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 EDAEVDRVFAGKVWGAWHLSEAAAGLK--LDFFINTSSIAAVWGGYGQTA
Mvan_0269|M.vanbaalenii_PYR-1 EDSEVDRVFAGKVWGAWHLSEAAADLQ--LDFFLGTSSIASVWGGYGQTA
Mflv_0405|M.gilvum_PYR-GCK DDAEVDRVFAGKVWGAWHLSEATSDLQ--LDFFISTSSIASVWGGFGQAA
MSMEG_0408|M.smegmatis_MC2_155 DDAEVDRVFAGKVWGAWHLSEALTDLRTDLDFFVSTSSIASVWGGFGQTA
Rv1662|M.tuberculosis_H37Rv --------------------------------------------------
Mb1690|M.bovis_AF2122/97 --------------------------------------------------
MMAR_2472|M.marinum_M --------------------------------------------------
MAV_3108|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MUL_2005|M.ulcerans_Agy99 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 YSAANAFLDGLAWRLREQGIAGTSVNFGPWSAGMADAESRARLEQRGIKT
Mvan_0269|M.vanbaalenii_PYR-1 YGAANAFLDGLAWRLREQGISGVSINFGPWSAGMADAESRARLDQRGVRT
Mflv_0405|M.gilvum_PYR-GCK YGAANAFLDGLAWRLREQGVAGVSVNFGPWSAGMADAQSRARLEQRGIKT
MSMEG_0408|M.smegmatis_MC2_155 YGAANAFLDGLAWRLRERGVTAVSVNFGPWAAGMADAESRARLEQRGVRT
Rv1662|M.tuberculosis_H37Rv --------------------------------------------------
Mb1690|M.bovis_AF2122/97 --------------------------------------------------
MMAR_2472|M.marinum_M --------------------------------------------------
MAV_3108|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MUL_2005|M.ulcerans_Agy99 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 LSPTDALAGLADVVAASGS-NAVQGVIARIDWARFLPLYQQAGKRGFLAE
Mvan_0269|M.vanbaalenii_PYR-1 LSPADALAGLADVVTAAEAPGPAQGIVARIDWERFLPLYQQAGRRAFLAE
Mflv_0405|M.gilvum_PYR-GCK LSPADALAGLSDAVISAAP----HPVVARVDWSRFLPLYQQAGRRGFLAE
MSMEG_0408|M.smegmatis_MC2_155 LSPAEALAGMADVVAGPVQ-----GVVAKIDWSRFLPLYQQAGRRAFLSE
Rv1662|M.tuberculosis_H37Rv --------------------------------------------------
Mb1690|M.bovis_AF2122/97 --------------------------------------------------
MMAR_2472|M.marinum_M --------------------------------------------------
MAV_3108|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MUL_2005|M.ulcerans_Agy99 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 LDREVPSHLAGV--AGAQSGSTQLVERLANAPVQQRKKLLTDYLRDAVAE
Mvan_0269|M.vanbaalenii_PYR-1 LEREVPDTAP----AATPSGRTELVERLTNAPVQQRKKLLTDYLRTAVAE
Mflv_0405|M.gilvum_PYR-GCK LERELPAAPAQQGPAVTASGRTPLVERLTTAPLQQRKRLLTDYLRDAVAE
MSMEG_0408|M.smegmatis_MC2_155 LESELPAAATGAAAPATVPGKPPLVEQLTKAPVQQRKSLITNYLRNAVAE
Rv1662|M.tuberculosis_H37Rv -------------------------MSGTTTHVD--------YLKRLTAD
Mb1690|M.bovis_AF2122/97 -------------------------MSGTTTHVD--------YLKRLTAD
MMAR_2472|M.marinum_M -------------------------MTETTKHVD--------YLKRLTAD
MAV_3108|M.avium_104 -------------------------MPGTEQHLD--------YLKRLTAD
MLBr_00135|M.leprae_Br4923 -------------------------MTASVEGADQKSEKLISYLKKVVVE
MUL_2005|M.ulcerans_Agy99 -------------------------MTTSGESADQQNDKLFRYLKKVAVE
TH_4621|M.thermoresistible__bu --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 VTRVDVSEIREDAGFFDLGMDSLMAVELRRRMEQGVGKEIPVTLVMDHPR
Mvan_0269|M.vanbaalenii_PYR-1 ITRVDATEIREDAGFFDLGMDSLMAVELRRRIEQGVGREIPATLAMDHPR
Mflv_0405|M.gilvum_PYR-GCK VTRVDAAEIREDAGFFDLGMDSLMAVELRRRIETGVGKEIPVTLVMDHPR
MSMEG_0408|M.smegmatis_MC2_155 VTRVDADEIRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPR
Rv1662|M.tuberculosis_H37Rv LR------------------------RTRRRLSD----------------
Mb1690|M.bovis_AF2122/97 LR------------------------RTRRRLSD----------------
MMAR_2472|M.marinum_M LR------------------------RTRRRVAE----------------
MAV_3108|M.avium_104 LR------------------------RTRRRVAE----------------
MLBr_00135|M.leprae_Br4923 LD------------------------ETRARLRE----------------
MUL_2005|M.ulcerans_Agy99 LD------------------------EARARLRE----------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 ISDVADYLLGDVLGLAEQA--KPAAQLASAVTGRTDEPIAIVAVSCRFPG
Mvan_0269|M.vanbaalenii_PYR-1 LSDVADYLLGEVLGLAEQAPAKAGSQPASAAANRTDEPIAIVAVSCRFPG
Mflv_0405|M.gilvum_PYR-GCK LSDAADYLLGDVLGLTEAA---TAPKAATVVSTAADEPIAIVAVSCRFPG
MSMEG_0408|M.smegmatis_MC2_155 LSDAADYLLVEVLGLGEQT----NVRQASTVTARTDDPIAVVAVSCRFPG
Rv1662|M.tuberculosis_H37Rv ------------------------------LEAKLSEPVAVVGMGCRYPG
Mb1690|M.bovis_AF2122/97 ------------------------------LEAKLSEPVAVVGMGCRYPG
MMAR_2472|M.marinum_M ------------------------------LEDKLSEPVALVGMGCRYPG
MAV_3108|M.avium_104 ------------------------------LEGRLSEPVAVVGMACRYAG
MLBr_00135|M.leprae_Br4923 ------------------------------YEQRATEPVAVVGIGCRFPG
MUL_2005|M.ulcerans_Agy99 ------------------------------YEQRATEPVAVVGIGCRFPG
TH_4621|M.thermoresistible__bu ---------------------------VNIVGDTPVNAVAVIGMACRLPG
:.:*::.:.** .*
MAB_0939|M.abscessus_ATCC_1997 APD-PEAFWDVLSGGVDAIREVPEDR-FDIDEFYDPDPEVAGKTYTRFGG
Mvan_0269|M.vanbaalenii_PYR-1 APD-PEAFWEVLAGGVDAIREVPEDR-FDIDEFYDPDPDAAGKTYTRFGG
Mflv_0405|M.gilvum_PYR-GCK APN-PEAFWDLLSGGVDAIREVPEDR-FDIDEFYDPDPDAAGKTYTRYGG
MSMEG_0408|M.smegmatis_MC2_155 APD-PESFWELLAGGVDAIREVPEDR-WDIDEFYDPDPDTPGKTYTRFGG
Rv1662|M.tuberculosis_H37Rv GVDSPETLWELVAQGRDAVSDFPADRGWDVDGLFDPDPDACGKMYTRRGT
Mb1690|M.bovis_AF2122/97 GVDSPETLWELVAQGRDAVSDFPADRGWDVYGLFDPDPDACGKMYTRRGT
MMAR_2472|M.marinum_M GADSPESLWEMLTQGRDAVSEFPSDRGWDIDAMFDPDPDARGKTYTRRGG
MAV_3108|M.avium_104 GVDSPEALWDLVIEGRDTVSDFPVDRGWDVEGLYDPDPDAKGKMYTRQGS
MLBr_00135|M.leprae_Br4923 GVDSPDRLWDVVSECRDVVSEFPTDRGWDVDGLFDPDPDAEGKTYTRWGA
MUL_2005|M.ulcerans_Agy99 GADGPEGLWDLVSQGRDAVTEFPNDRGWDTEGLFDPDPDAEGKTYTRWGA
TH_4621|M.thermoresistible__bu GIDSPQRLWEALLRGDDMVTEIPVDR-WDADDYFDPEPGVPGRTVSRWGA
. : *: :*: : * : :.* ** :* :**:* . *: :* *
MAB_0939|M.abscessus_ATCC_1997 FLDGIDGFDPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYSPAALRG
Mvan_0269|M.vanbaalenii_PYR-1 FLDGIDGFDPEFFGISPREAVWIEPQQRLMLETVWEGLERAGLAPADLRG
Mflv_0405|M.gilvum_PYR-GCK FLDHIDEFDPEFFGLSPREAVWIEPQQRLMLETVWEGLERAGYAPSALRG
MSMEG_0408|M.smegmatis_MC2_155 FLDGIDGFDPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYAPSDLRG
Rv1662|M.tuberculosis_H37Rv FLEHAGDFDAGFFGIGPSEALAMDPQQRLLLEVSWEALERTGIDPTKLRG
Mb1690|M.bovis_AF2122/97 FLEHAGDFDAGFFGIGPSEALAMDPQQRLLLEVSWEALERTGIDPTKLRG
MMAR_2472|M.marinum_M FLADAGDFDAGFFGVGPNEALAMDPQQRLMLEVSWEALERSGIDPTTLRG
MAV_3108|M.avium_104 FLQHAGDFDAGFFGIGPSEALAMDPQQRIMLEICWEALERAGIDPSALRG
MLBr_00135|M.leprae_Br4923 FLDDAAGFDAGFFGIAPSEVLAMDPQQRLMLEVSWEALEYAGIDPLSLRG
MUL_2005|M.ulcerans_Agy99 FVENATNFDAGFFGIPPSEVLAMDPQQRLMLEVSWEALEHAGIDPMSLRG
TH_4621|M.thermoresistible__bu FLDDVAGFDPEFFGISEREAISIDPQQRLLLETSWEAMEHAGLTPADVEG
*: **. ***: *.: ::****::** **.:* :* * :.*
MAB_0939|M.abscessus_ATCC_1997 SRTGIFAGVGANEYAHLLSSESIDKIEPYFITGNALNAISGRVAFALGFE
Mvan_0269|M.vanbaalenii_PYR-1 SRTGIFVGVAANEYAHLLSSESIEKIEPHFITGNALNAISGRVAFALGLE
Mflv_0405|M.gilvum_PYR-GCK SRTGVFVGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGLE
MSMEG_0408|M.smegmatis_MC2_155 SRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGFE
Rv1662|M.tuberculosis_H37Rv SATGVFAGVIHAGYGGQLSG----ELEGYGLTGSTLSVASGRVAYVLGLE
Mb1690|M.bovis_AF2122/97 SATGVFAGVIHAGYGGQLSG----ELEGYGLTGSTLSVASGRVAYVLGLE
MMAR_2472|M.marinum_M SATGVFVGVIHAGYGGEVKG----ELEGYGLTGSTLSVASGRVAYVLGLE
MAV_3108|M.avium_104 TATGVFAGVIHAGYGGEVKG----ELEGYGLTGSTLSVTSGRVSYVLGLE
MLBr_00135|M.leprae_Br4923 SATGVFTGIFAPSYGSRDTG----GLQGYGLTGTAVSVASGRVSYVLGLE
MUL_2005|M.ulcerans_Agy99 SSTGVFTGIFAPSYGGKDVG----ALQGYGLTGSPVSVASGRVAYVLGLE
TH_4621|M.thermoresistible__bu SSTGVFVGLSHDDYALLTSDAG-ALEEAYGFTGSAFSMASGRIAYRLGVH
: **:*.*: *. : : :**.... ***::: **..
MAB_0939|M.abscessus_ATCC_1997 GPAVAVDTACSSALVAVHQAVQALHSGDCDLALAGGVNVLLSPVTVIAAS
Mvan_0269|M.vanbaalenii_PYR-1 GPAVAVDTACSSALVAVHQACQALHSGDCDLALAGGVNVLLSPVTSVAAS
Mflv_0405|M.gilvum_PYR-GCK GPAVAVDTACSSSLVAVHQATQALRSGDCDMALAGGVNVLLSPVTVVAAS
MSMEG_0408|M.smegmatis_MC2_155 GPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAAS
Rv1662|M.tuberculosis_H37Rv GPAVSVDTACSSSLVALHLAVQSLRSGECDLALAGGVTVMATPAAFVEFS
Mb1690|M.bovis_AF2122/97 GPAVSVDTACSSSLVALHLAVQSLRSGECDLALAGGVTVMATPAAFVEFS
MMAR_2472|M.marinum_M GPAVSVDTACSSSLVALHLAAQSLRSRECDLALVGGVTVMATPAAFVEFS
MAV_3108|M.avium_104 GPAVSVDTACSSSLVAMHLAAQSLRSGECDLALAGGVTVMATPAAFVEFS
MLBr_00135|M.leprae_Br4923 GPAVSVDTACSSSLVAIHWAMSSLRSGECDLALAGGVTVMGLPSIFVGFS
MUL_2005|M.ulcerans_Agy99 GPALSVDTACSSSLVAIHWAMASLRSGECDMALAGGVTVMGLPSIFVGFS
TH_4621|M.thermoresistible__bu GPAVTVDTACSSSLLAVHMACRSLQVGESDLALAGGAMVMLEPRKYTSAS
***::*******:*:*:* * :*: :.*:**.**. *: * *
MAB_0939|M.abscessus_ATCC_1997 RARMLSPVGRCKTFDASADGYVRSEGCGILVLKRLSDAERDGDRVLAVIP
Mvan_0269|M.vanbaalenii_PYR-1 RARMLSPVGRCKTFDASADGYVRSEGCGILVLKRLGDAVRDGDRVCAVIP
Mflv_0405|M.gilvum_PYR-GCK RARMLSPVGRCKTFDASADGYVRSEGCGILVLKRLSDAVRDGDRVCAVIA
MSMEG_0408|M.smegmatis_MC2_155 RARMLSPVGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIP
Rv1662|M.tuberculosis_H37Rv RQRALARDGRCKVYAGAADGTAWSEGAGVLVVERLVDARRLGHPVLALVR
Mb1690|M.bovis_AF2122/97 RQRALARDGRCKVYAGAADGTAWSEGAGVLVVERLVDARRLGHPVLALVR
MMAR_2472|M.marinum_M RQRALAADGLCKAYAGAADGTTWSEGAGVLVVERLADAQRLGHPVLAVVR
MAV_3108|M.avium_104 RQRALAPDGRCKVYAGAADGTSWSEGAGVLVLERLADARRLGHPVWAVLR
MLBr_00135|M.leprae_Br4923 RQRGLAADGRCKAFARAADGTGWGEGAGVVVLERLSDAQRLGHTVLAVVR
MUL_2005|M.ulcerans_Agy99 RQRGLAADGRCKAFAAAADGTGWGEGAGVLVLERLSDAQRNGHNVLAVVR
TH_4621|M.thermoresistible__bu GLGMLSPTGRCHAFDVAADGFVRSEGSVMLLLKRLPDALRDNDRILAVVR
*: * *:.: :*** .**. :::::** ** * .. : *::
MAB_0939|M.abscessus_ATCC_1997 GSAVNQDGASSGLTVPNGGAQQRLIGSVLARAGLVGGDVDYLEAHGTGTP
Mvan_0269|M.vanbaalenii_PYR-1 SSAVNQDGASSGLTVPNGGAQQRLIGMALARAGLSGGDVDYLEAHGTGTP
Mflv_0405|M.gilvum_PYR-GCK GSAVNQDGASSGLTVPNGGAQQRLIGTVLARAGITGGEVDYLEAHGTGTP
MSMEG_0408|M.smegmatis_MC2_155 ASSVNQDGASSGLTVPNGGAQQRLIEATLARAGLSGADVDYLEAHGTGTP
Rv1662|M.tuberculosis_H37Rv GSAVNQDGASNGLTAPNGPSQQRVIRAALASARLRAVEVDVVEGHGTGTM
Mb1690|M.bovis_AF2122/97 GSAVNQDGASNGLTAPNGPSQQRVIRAALASARLRAVEVDVVEGHGTGTM
MMAR_2472|M.marinum_M GSAVNQDGASNGLTAPNGPSQQRVIRAALASARLGVADVDVVEGHGTGTV
MAV_3108|M.avium_104 GSAVNQDGASNGLTAPNGPSQQRVIRAALANAGLSAVDVDVVEGHGTGTV
MLBr_00135|M.leprae_Br4923 GSAVNQDGASNGLTAPNGLAQQRVIQAALTNAGLSSADVDVVEAHGTATT
MUL_2005|M.ulcerans_Agy99 GSAINQDGASNGLTAPNGLTQQRVIQAALANCGLTSADVDVVEAHGTATT
TH_4621|M.thermoresistible__bu GTAANQDGRTENISTPSIQAQADVYRSALAVAGVDPATVGMVEAHGTGTP
.:: **** :..::.*. :* : .*: . : *. :*.***.*
MAB_0939|M.abscessus_ATCC_1997 LGDPIEVQAAAAAYGGSRDADRPLLMGSVKSNIGHTESASGAAGLIKVVL
Mvan_0269|M.vanbaalenii_PYR-1 LGDPIEVQAAAAAYGASRDADRPLLMGSVKTNIGHLESASGAAGLIKVVL
Mflv_0405|M.gilvum_PYR-GCK LGDPIEVQAAAAAYAGARDADRPLLMGSVKTNIGHTESASGAAGLIKVVL
MSMEG_0408|M.smegmatis_MC2_155 LGDPIEVQAAAAAYGAGRDADRPLLMGSVKTNIGHTESASGAAGLIKVVL
Rv1662|M.tuberculosis_H37Rv LGDPIEAQALLATYGQDR--VEPLWLGSIKSNIGHTSAAAGVAGVIKMVQ
Mb1690|M.bovis_AF2122/97 LGDPIEAQALLATYGQDR--VEPLWLGSIKSNIGHTSAAAGVAGVIKMVQ
MMAR_2472|M.marinum_M LGDPIEAQAILATYGQDR--TEPLWLGSIKSNIGHTSAAAGVAGLIKMVL
MAV_3108|M.avium_104 LGDPIEAQALLATYGQDRPADRPLWLGSIKSNIGHTSAAAGVAGVIKMVQ
MLBr_00135|M.leprae_Br4923 LGDPIEAQALLATYGQGRPADQPLWVGSIKSNMGHTQAAAGVAGVIKMVQ
MUL_2005|M.ulcerans_Agy99 LGDPIEAEALLATYGQGRPTDQPLWVGSIKSNMGHTQAAAGVAGVIKMVQ
TH_4621|M.thermoresistible__bu VGDPIEYNSLTQVYGKTG----PCALTSVKTNFGHAESAAGALGMMKAIL
:***** :: .*. * : *:*:*:** .:*:*. *::* :
MAB_0939|M.abscessus_ATCC_1997 SLQNGVLPQSLHFDNPSPHIPWESLPVRVVDKAIPWQA-NGRPRRAGVSS
Mvan_0269|M.vanbaalenii_PYR-1 SLQHNLLPQSLHFENPSPHIPWDSLPVRVVDKAIPWQA-DGRPRRAGVSS
Mflv_0405|M.gilvum_PYR-GCK SLQHETLPQSLHFDTPSPHIPWDSLPVRVVDTAMPWQP-NGRPRRAGVSS
MSMEG_0408|M.smegmatis_MC2_155 SLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQT-NGRVRRAGVSS
Rv1662|M.tuberculosis_H37Rv AMRHGVMPKTLHVDVPTPHVDWSVGAVSLLTQPRAWSV-HGRPRRAGVSS
Mb1690|M.bovis_AF2122/97 AMRHGVMPKTLHVDVPTPHVDWSVGAVSLLTQPRAWSV-HGRPRRAGVSS
MMAR_2472|M.marinum_M AMQHGVLPQTLHVDVPTPHVDWSAGAVSLLTESRPWPD-LGRPRRAGVSS
MAV_3108|M.avium_104 ALRHGVMPKTMHVDVPSPHVDWSAGAVSLLTDPRPWPE-HGGPRRAGVSS
MLBr_00135|M.leprae_Br4923 AMRHHVMPATLHVDEPSPRVDWTTGAVSVLTEARDWSV-EGRPRRAGVSS
MUL_2005|M.ulcerans_Agy99 AMRHGLMPASLHVDEPSKRVDWESGAVSVLAEARDWPD-AGRPRRAGVSS
TH_4621|M.thermoresistible__bu ALQHGVVPQNLHFTRLPDEMAAIETNLFVPQATTLWPVREGCPRRAAVSS
:::: :* .:*. . .: : : . * * ***.***
MAB_0939|M.abscessus_ATCC_1997 FGFTGTNAHVLIEEAPQPQATP----------DEDDASTPQSAPVSVLPL
Mvan_0269|M.vanbaalenii_PYR-1 FGFTGTNAHVLIEEAPLPQAAD----------PVEEPDT-RALPVGVLAL
Mflv_0405|M.gilvum_PYR-GCK FGFTGTNAHVLIEEAPTDLAGPTEPTAPAEPVDEDAAADPAPAPVEVLPL
MSMEG_0408|M.smegmatis_MC2_155 FGFTGTNAHVLVEEAPPQLHTADAAP----VEPAATAEAGTDDSPQVLAL
Rv1662|M.tuberculosis_H37Rv FGISGTNAHVILEQAPVVESV-----------VPEVASPT-AASAVPWVL
Mb1690|M.bovis_AF2122/97 FGISGTNAHVILEQAPVVESV-----------VPEVASPT-AASAVPWVL
MMAR_2472|M.marinum_M FGISGTNAHVILEQAPTAEHD-----------LAEPDRG---APTVPWVL
MAV_3108|M.avium_104 FGISGTNAHVIVEQAPAAAET-----------EAAPASSTMPDAVVPWVV
MLBr_00135|M.leprae_Br4923 FGISGTNAHVILEEAPTPVEAS----------YSTAD--QQRLSVVPWVV
MUL_2005|M.ulcerans_Agy99 FGISGTNAHVILEEAPAPEAVP----------DSESNKGEPSLPVVPWVI
TH_4621|M.thermoresistible__bu YGMSGTNVHAVLEQAPEPVQRP------------EESADTDAAGPLVFAL
:*::***.*.::*:** :
MAB_0939|M.abscessus_ATCC_1997 SARSPEALAAVAQRYESWLAAH-PDVDLEDVCLTAGRGRSHFEHRAALVV
Mvan_0269|M.vanbaalenii_PYR-1 SARSPEALTALAQRYEAWLSAH-PDADLADVCRTAGTGRSHFEHRAALVV
Mflv_0405|M.gilvum_PYR-GCK SARSPEALVALAQRYETWLTAH-PEADLADVCRTAGTGRSHFEHRAALVV
MSMEG_0408|M.smegmatis_MC2_155 SARSPEALVELARRYDDWLSAT-PGLDIADVCHTAGVGRSHFEYRAALVV
Rv1662|M.tuberculosis_H37Rv SARSEQALAGQAQRLLAFVAAN-PDLDPIDVGWSLVKTRAMFEHRAVVVG
Mb1690|M.bovis_AF2122/97 SARSEQALAGQAQRLLAFVAAN-PDLDPIDVGWSLVKTRAMFEHRAVVVG
MMAR_2472|M.marinum_M SARSAPALANQAQRLLSWAEEH-PDLDPVDVGWSLAATRSLFEHRAVVVG
MAV_3108|M.avium_104 SARSAEALAGQARRLLDHVTAD-AQASPLDVGWSLVSTRAVFEHRAVVVG
MLBr_00135|M.leprae_Br4923 SGRSTAALMAQASRLAFYVQAD-PEVDPVDVGCALAA-RSVFEHRAVVVG
MUL_2005|M.ulcerans_Agy99 SARSAEALTAQAGRLLAHVQAD-PQSNPVDIGFSLAG-RSAFEHRAVVVG
TH_4621|M.thermoresistible__bu SSTSAEELRRTAGRLAEWVEAHTDEVVPADLAYTLARRRAHRPVRTTVIA
*. * * * * *: : *: *:.::
MAB_0939|M.abscessus_ATCC_1997 DSIQTAREGLLELAQNRLRPGVVRGEHTNHPTTAWLFTGQGSQYPGMARE
Mvan_0269|M.vanbaalenii_PYR-1 DSVAAAREGLAELAQNRLRPGVVRGEHTHHPTTAWLFTGQGSQFPGMARE
Mflv_0405|M.gilvum_PYR-GCK DSVESARIALTDLAQNRLRPGVVRGEHLNHPTTAWMFTGQGSQYPGMARE
MSMEG_0408|M.smegmatis_MC2_155 DSVERAREGLAALAEGRTPAGVVRGEHVHRPTTAWLFTGQGSQYPGMARE
Rv1662|M.tuberculosis_H37Rv ADRGALLAGLAALAAGESGAGVAVGRARSVGKTVFVFPGQGAQWVGMGAQ
Mb1690|M.bovis_AF2122/97 ADRGALLAGLAALAAGESGAGVAVGRARSVGKTVFVFPGQGAQWVGMGAQ
MMAR_2472|M.marinum_M TDRTQLMDGLAGVVAGEPGAGVVVGRARSTGKTVFVFPGQGAQYLGMGRV
MAV_3108|M.avium_104 RERGALATGLAGLASGRPGPATVVGRARSTGKTVLVFPGQGSQTLGMGRQ
MLBr_00135|M.leprae_Br4923 ESREQLIAGLAGLAVGESGAGVAIGQAAPLGKTVVVFPGQGAQRIGMGRE
MUL_2005|M.ulcerans_Agy99 ADRQQLLTGLATLADGAPGAGVVTGQAGSVGKTAVVFPGQGSQRIGMARE
TH_4621|M.thermoresistible__bu DGVEALTAGLREVADGDAPYQPAVGMDDKAP--VWVFSGQGSQWAGMGAE
.* :. . . * . :*.***:* **.
MAB_0939|M.abscessus_ATCC_1997 LFDAEPVFAETVTRCAEAVKDIVTRPLLEVMFATDRETGGKAGEALRHTS
Mvan_0269|M.vanbaalenii_PYR-1 LFETEPVFADAVTRCADAVKDILPRPLLEVLFAADRESG----EALRHTS
Mflv_0405|M.gilvum_PYR-GCK LFDTEPVFADTVTRCADAVADLLPRPLLDVMFAGGREAGVPPTETLRHTS
MSMEG_0408|M.smegmatis_MC2_155 LFDTQPVFAQTVRQCAEAVADMLPRPLLDVLFATDRETA----DLLQHTS
Rv1662|M.tuberculosis_H37Rv LYAELPLFALAFDAVAEELDRHLRLPLRNVLWEGD-------EALLTSTE
Mb1690|M.bovis_AF2122/97 LYAELPLFALAFDAVAEELDRHLRLPLRNVLWEGD-------EALLTSTE
MMAR_2472|M.marinum_M LYERFSAFSTAFDAAAAELDAHLRLPLRQVMWGTD-------EGLLESTE
MAV_3108|M.avium_104 LYERFEVFAGALDEAVAVVDEHSRLSVREVMWGAD-------PELLQSTE
MLBr_00135|M.leprae_Br4923 LCSQLPVFAEEFDAVTGELDRHMRLPLRDVVWGAD-------AGLLDSTE
MUL_2005|M.ulcerans_Agy99 LHDQLPVFAEAFDAVADELDRHLRIPLCEVMWGSD-------VALLDSTE
TH_4621|M.thermoresistible__bu LLATEQVFAAKIAEIEPLVARESGFSVTEAMTASET---------VTGID
* *: . : .: :.: : .
MAB_0939|M.abscessus_ATCC_1997 FAQPALFAVEMGLARLWQSWGIEPDVVLGHSVGQYAAACVAGVFSIEDGA
Mvan_0269|M.vanbaalenii_PYR-1 FAQPAIFAVEMGLARLWQSWGIEPDVVLGHSVGQYAAACVAGVFSLEDGA
Mflv_0405|M.gilvum_PYR-GCK FAQPALFAVEMGLARLWQSWGIVPDVVLGHSVGQYAAACVAGVFSLEDGA
MSMEG_0408|M.smegmatis_MC2_155 FAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACVAGVFSLDDGA
Rv1662|M.tuberculosis_H37Rv FAQPALFAIEVALATLLQHWGISPDFLIGHSVGEIAAAHLAGVLSLTDAA
Mb1690|M.bovis_AF2122/97 FAQPALFAIEVALATLLQHWGISPDFLIGHSVGEIAAAHLAGVLSLTDAA
MMAR_2472|M.marinum_M FAQPALFAVEVALAALLSQLGVVPDLVLGHSVGEISAAHVAGVLSLPDAA
MAV_3108|M.avium_104 FAQPALFVFEVALAALWESLGVTPDVVMGHSVGEIAAACVAGVLSLRDAA
MLBr_00135|M.leprae_Br4923 FAQPALFAVEVALFAVLQHWGLQPDFVMGHSIGELAAAYVAGVLAPADAA
MUL_2005|M.ulcerans_Agy99 FAQAALFAVEVALFAALQRWGLQPDFVMGHSVGELSAAYVAGVLTLVDAA
TH_4621|M.thermoresistible__bu RVQPTLFAIQVALAATMQSYGVRPGAVIGHSLGEVAAAVVAGALSLEDGV
.*.::*..::.* . .: *. ::***:*: :** :**.:: *..
MAB_0939|M.abscessus_ATCC_1997 RLIAERGRLFGGLPAGGRMVAVFSDAKHVEQIAGEFPR--VSVGAYNGPN
Mvan_0269|M.vanbaalenii_PYR-1 RLMAERGRMFGSLPEGGRMVAVFTDAKLVEEIAGDFPR--VSVGAYNGPN
Mflv_0405|M.gilvum_PYR-GCK RLMAERGRLFGSLPEGGRMVAVFADAKRVEQVAADFPR--VSVGAYNGPN
MSMEG_0408|M.smegmatis_MC2_155 RLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAGEFPR--VSVGAYNGPN
Rv1662|M.tuberculosis_H37Rv GLVAARGRLMAELPAGGVMVVVAASEEEVLPVLVDG----ANLAAVNAPH
Mb1690|M.bovis_AF2122/97 GLVAARGRLMAELPAGGVMVVVAASEEEVLPVLVDG----ANLAAVNAPH
MMAR_2472|M.marinum_M RLVAARGRLMAGLAAGGAMVAVAASEQEVTPLLGSG----VAVAAVNGPD
MAV_3108|M.avium_104 RLVAARGALMAALPPGGVMVAVTAGESQVGPLLGGG----VSIAAVNGPD
MLBr_00135|M.leprae_Br4923 MLVVARGRLMQSMPAGGTMWAVAASEDEVVSLLGEG----VGIAAINAPE
MUL_2005|M.ulcerans_Agy99 MLVVARGRLMQALPAGGAMVAVAAAEDEVLPSLTDG----VGIAAINAPK
TH_4621|M.thermoresistible__bu KVICRRSRLCLRLAGAGAMAAIELPAQAVREFLAARGVDDVVLSVIASPE
:: *. : :. .* * .: . * . :.. .*.
MAB_0939|M.abscessus_ATCC_1997 -TVLSGPGEDLEQAVARFQEEGIRCTWLETSHAFHSELLDPILDEFESYA
Mvan_0269|M.vanbaalenii_PYR-1 -TVLSGPGEDLEQIVDRFGDDGVRCTWLQTSHAFHSELLDPVLDEFESYA
Mflv_0405|M.gilvum_PYR-GCK -TVLSGPGEDLEQIVGTFGEDGIRCTWLETSHAFHSELLDPVLDEFESYA
MSMEG_0408|M.smegmatis_MC2_155 -TVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDEFEAYA
Rv1662|M.tuberculosis_H37Rv SVVVSGCEAAVSDIADHFARRGRRVHRLAVSHAFHSLLMEPMLAEFTRIA
Mb1690|M.bovis_AF2122/97 SVVVSGCEAAVSDIADHFARRGRRVHRLAVSHAFHSLLMEPMLAEFTRIA
MMAR_2472|M.marinum_M SVVISGPEAAVGEVVDRIAALGRRTHRLAVSHAFHSELMDPMLPDFAEVL
MAV_3108|M.avium_104 AVVLSGEQEAVAAVADRLAGSGARVHRLAVSHAFHSALMEPMLDGFAAAA
MLBr_00135|M.leprae_Br4923 SVVISGPQAAVSAIADKFAAQGRRVHQLAVSHAFHSPLMEPMLEEFVRVA
MUL_2005|M.ulcerans_Agy99 SVVISGAEAAVTAISDQFAQQGRRVHRLAVSHAFHSPLMEPMLEEFARIA
TH_4621|M.thermoresistible__bu STVIGGATDTVRELVAAWEAQGVMAREVAVDVASHSPQVDPILDELEEIL
.*:.* : * : .. * ** ::*:* :
MAB_0939|M.abscessus_ATCC_1997 AQVQFAAPTLPLVCNRTGAVLTAQT-PIDGQYWRRHSRQPVQFAESVRTV
Mvan_0269|M.vanbaalenii_PYR-1 AQFQFATPTLPLVCNRTGTVLTAQT-PLDAQYWRRHSRQPVQFAESVRTV
Mflv_0405|M.gilvum_PYR-GCK AQLQFAAPTLPLVCNRTGAVLTGQT-SLDAQYWRRHSRQPVQFAESVRTV
MSMEG_0408|M.smegmatis_MC2_155 AQFQFAAPTLPLVCNRTGAVLTGQT-PLDAQYWRRHSRQPVQFAESVRTV
Rv1662|M.tuberculosis_H37Rv AGISVSKPRIPLVSNVTGQMAGAG--YGDGQYWVEHARRPVRFAEGVQLL
Mb1690|M.bovis_AF2122/97 AGISVSKPRIPLVSNVTGQMAGAG--YGDGQYWVEHARRPVRFVEGVQLL
MMAR_2472|M.marinum_M KGVSASQPRISLVSNVTGQLAEAG--YGSAAYWVEHVRKPVRFADSVALA
MAV_3108|M.avium_104 AGIEPRPPRIPLVSNLTGQLAGPG--YGTPQYWVDHVRRPVRFVDGVRLA
MLBr_00135|M.leprae_Br4923 AQVEVRKPQIGLVSNVTGELAGPD--FGSPQYWGEHVSRAVRFVDSARHL
MUL_2005|M.ulcerans_Agy99 AQVEAREPQIALVSNVTGELASADGGFGSAQYWVEHVRRAVRFADSARQL
TH_4621|M.thermoresistible__bu ADLQPMTPTVPYYSATSYDPREKP--VCDADYWVDNLRHEVRFAAAVQAA
.. * : . : ** : : *:*. ..
MAB_0939|M.abscessus_ATCC_1997 AALGCSVLMEIGPQPVLTGAAVQVWPEHLAPPRAIVSLRKGVEDRRQIAD
Mvan_0269|M.vanbaalenii_PYR-1 AALGCSVLMEIGPQPVLTGSAVQVWPEHLAAPRAIVSLRKGVSDRRQITE
Mflv_0405|M.gilvum_PYR-GCK AALGCSVLMEIGPQPVLTGAAVQVWPEHLAAPRAIASLRKGVADRRQIAD
MSMEG_0408|M.smegmatis_MC2_155 AALGCSVLMEIGPQPVLTGAAVQVWPEHMAAPRAVASLRKGVADRRQIAD
Rv1662|M.tuberculosis_H37Rv NAVGATRFVEVGPGGGLTALVEQSLPL--GEALSVAMMRREHPEVSSVLG
Mb1690|M.bovis_AF2122/97 NAVGATRFVEVGPGGGLTALVEQSLPL--GEALSVAMMRREHPEVSSVLG
MMAR_2472|M.marinum_M ESLGAAAFVEVGPSGGLTALVEQSLTR--ETP-AVPLLIKDRPENDALLL
MAV_3108|M.avium_104 ESQGAGVFLEVGPGAALTSAVEQSLTS--DRAMSVVTMPKGRPEVDSLLT
MLBr_00135|M.leprae_Br4923 QTLGATHFIESGPSSGLMGAIEQSLAP--AEAVVVSMMGKDRPELASVLG
MUL_2005|M.ulcerans_Agy99 HTLGVTHFVEVGPGSGLTGSIEQSLAP--AEAVVVSMLGKDRPEVASVLT
TH_4621|M.thermoresistible__bu LEDGFRVFGELSPHPLLTRAVEQTARGLDMPVAALPAMRREQEMPHGVRT
* : * .* * * : : : :
MAB_0939|M.abscessus_ATCC_1997 ALASAYVSGHRPNFAALQRHP-RRTVELPTYPFQRRRFWPK---SSGTAI
Mvan_0269|M.vanbaalenii_PYR-1 ALAAAYVGGHRPDFGALYRRP-GRAVALPTYPFQRRRFWPK---TSGITT
Mflv_0405|M.gilvum_PYR-GCK ALAAAYIGGHKPDFAALHEQR-GVRLELPTYPFQRRRFWPK---SAGMAI
MSMEG_0408|M.smegmatis_MC2_155 ALASAYVGGHRPDFAAVHRQP-RRPVELPTYPFQRRRFWPK---ASSIAV
Rv1662|M.tuberculosis_H37Rv AVATLFTAGAQMDWPAVFGSP-GRRIELPTYAFQRQRYWLPPTSAGSADI
Mb1690|M.bovis_AF2122/97 AVATLFTAGAQMDWPAVFGSP-GRRIELPTYAFQRQRYWLPPTSAGSADI
MMAR_2472|M.marinum_M GLGQLFADGRALDWREAFAGLGAQRTDLPTYGFVRRRYWLKELGVDQTKL
MAV_3108|M.avium_104 AAARLFTAGADVRWSAAFTGLHARRVDLPTYAFARRRFWLSGDAVGSANI
MLBr_00135|M.leprae_Br4923 AAGQLFATGMPVEWPAVFAGSSRRRVTLPTYAFQRRRFWETPGTDGTASV
MUL_2005|M.ulcerans_Agy99 AFGQLFSTGMSVDWPAVFAGSGATRVDLPTYAFQRRRFWEVPGADGPADA
TH_4621|M.thermoresistible__bu MVGDLFAAGAAVDFAALYPSG--RLVDAPLPTWTRRKLVLS--RENGEQQ
. : * : * : *::
MAB_0939|M.abscessus_ATCC_1997 EGGGGLPSG--ILGRGED-LASGD-SVYISRLSVRSQPWLSDHVIYGTVV
Mvan_0269|M.vanbaalenii_PYR-1 DG--PAVSG--ILGSAKD-LASGD-TVYTSRWSVRSQPWLADHVIYGTVV
Mflv_0405|M.gilvum_PYR-GCK DGRVGASAGSGILGSGKD-LASGD-SVYTSRLSVKTQPWLSDHVIYGTVV
MSMEG_0408|M.smegmatis_MC2_155 DGG-TAASG--ILGSGKD-LASGD-TIYTSRLSVKSQPWLADHVIYGTVV
Rv1662|M.tuberculosis_H37Rv SGVGLLAARHGLLGAVVEQPDSDV-VVLTGRLSVGEQRWLADHVIAGVVL
Mb1690|M.bovis_AF2122/97 SGVGLLAARHGLLGAVVEQPDSDV-VVLTGRLSVGEQRWLADHVIAGVVL
MMAR_2472|M.marinum_M TGAGLTGVGHPLLGAVVERPDVGG-LVLTGVLSPELHPWLRDHTVDGVVL
MAV_3108|M.avium_104 ASLGLAEAEHPLLGAVLDRPDSGG-VVLTGRLSTAAQPWLADHAVAGTVL
MLBr_00135|M.leprae_Br4923 SGLGLGSTEHALLGAVVERPDSGG-VVLTGRLSLANQPWLADHVIGGVVL
MUL_2005|M.ulcerans_Agy99 TGLGLGGAEHALLGAVVERPDSGG-VVLTGRLALADQPWLADHVIGGVVL
TH_4621|M.thermoresistible__bu TRGGCTITVHPLLGTHVRLPEEPERHVWQADLGTGAQPWLADHQIHTVAA
:** : . . : ** ** : ..
MAB_0939|M.abscessus_ATCC_1997 VPGATYAAMALAAVGTP--ARAKDVFFYEPIILPEKSSREVQLTLHPLED
Mvan_0269|M.vanbaalenii_PYR-1 VPGATYAAMALAAVGTP--ARVKDVFFYEPIILPEKASREVQLTLHPSED
Mflv_0405|M.gilvum_PYR-GCK VPGATYAAMALAAVGTP--AHAKDVFFYEPIILPEKSSREVQLTVHPSVD
MSMEG_0408|M.smegmatis_MC2_155 VPGATYAAMALAAVGTP--ARLKDVFFYEPIILPEKASREVQLTLHPADG
Rv1662|M.tuberculosis_H37Rv LAGAAFVELALRAADQVDCGVVEELTVVTPLVLPTVGGVQLQVVVGVGE-
Mb1690|M.bovis_AF2122/97 LAGAAFVELALRAADQVDCGVVEELTVVTPLVLPTVGGVQLQVVVGVGE-
MMAR_2472|M.marinum_M FPGAGFVELALRAGDEVGCPLVQELTLLAPLALPQTGTVRMQLVVGGAD-
MAV_3108|M.avium_104 FPGAGFVELALRAGDEVGCPVVEELTLSAPLSLPAGGTVQLQVVVADAAG
MLBr_00135|M.leprae_Br4923 FPGAGFVELVIRAGDEVGCAGVEELVLAAPLVLHPGSGVQVQVVVAAAD-
MUL_2005|M.ulcerans_Agy99 FPGAGFVELAIRAGDEVGCAVVEELVLAAPLVLHPGMGVQVQVIVGTAD-
TH_4621|M.thermoresistible__bu LPGAAYCEMALAAAREVIDSDGVEVRDVR-FEQMLLLDEQTEVSAVASAV
..** : :.: * :: : . ::
MAB_0939|M.abscessus_ATCC_1997 GSGSKFQVHSRPYGERDVDWSLNAEGTVVTGIGDDAEPAPEAAEPAEPVD
Mvan_0269|M.vanbaalenii_PYR-1 G-GQKFQVHSREYGERGTEWSLNAEGTVASGVDENPQ-----AEPSGPVD
Mflv_0405|M.gilvum_PYR-GCK G-ESKFQVHSRPYGERGAEWALNAEGVVASGVGDSPAAAG---DLEDPVD
MSMEG_0408|M.smegmatis_MC2_155 GSVLSFQIHSRPYGERGADWSLNAEGTVDTAGSDPDAAAD---EQSDPVD
Rv1662|M.tuberculosis_H37Rv -MGQRPVSIYSRNAESDSGWVLHARGVLGAKAVAPAADLS----VWPPLG
Mb1690|M.bovis_AF2122/97 -MGQRPVSIYSRNAESDSGWVLHARGVLGAKAVAPAADLS----VWPPLG
MMAR_2472|M.marinum_M ESGRRTVSVFSSTADGD-SWVLHAEGVLRASGVGHGVDLS----VWPPVG
MAV_3108|M.avium_104 QPGSRSVAVYSRVAQS--EWTLHAEGVLSEAAPAPAAELS----VWPPAD
MLBr_00135|M.leprae_Br4923 ESSRRAVSVYSRGDQSHGGWLLNAEGLLEVDAAEATVDLS----LWPPEG
MUL_2005|M.ulcerans_Agy99 DSGNRALSVYSRGDKSED-WLLNAEGMLGVEAASSGADLS----VWPPEG
TH_4621|M.thermoresistible__bu EPGTLEFAVETAKDGEHERRATAVLGAADDTEPPQAHDID------ALLA
. *
MAB_0939|M.abscessus_ATCC_1997 AAIERMERMRPMELFEIFADLELAWGPTWSGSLKSLWLG--EGEAIGDVL
Mvan_0269|M.vanbaalenii_PYR-1 EAIERLNRMRPQDLFETFADMELAWGPTWSGSLKSLWLG--EGEAIGDIL
Mflv_0405|M.gilvum_PYR-GCK EAIERLNRMRPQELFETFADLELAWGPTWSGSLKSLWLG--EGEAIGDIL
MSMEG_0408|M.smegmatis_MC2_155 EVIERLERMRPQDLFETFADLELAWGPTWSGSLKSLWLG--DGEAVGDIL
Rv1662|M.tuberculosis_H37Rv AAPVDVD-----GAYQRFAELGYEYGRAFQG-LTAMWRR--ESELFADVA
Mb1690|M.bovis_AF2122/97 AAPVDVD-----GAYQRFAELGYEYGRAFQG-LTAMWRR--ESELFADVA
MMAR_2472|M.marinum_M ASAVDVS-----DVYDRFAARGYGYGPAFRG-LRSVWRR--GREIYAEVV
MAV_3108|M.avium_104 AEAVDVA-----GGYDDLAGRGYGYGPAFRG-LRAVWRR--GAETFAEVE
MLBr_00135|M.leprae_Br4923 AESVDIS-----DAYPQLAERGYAYGPAFQG-LVAIWRR--GSELFAEVV
MUL_2005|M.ulcerans_Agy99 AESVDIS-----DGYAQLADRGYAYGPGFQG-LVGVWRR--DSELFAEVV
TH_4621|M.thermoresistible__bu EHPTRIEG---DELRQWFDQRGVQFGPAFTGLTAARIPEGTVTSVLAEVG
: : :* : * . . .::
MAB_0939|M.abscessus_ATCC_1997 VGEELAEQLGTEPMHPVLMDLCTGVAFPAFPALLAAEQGVNDLFLPLRYG
Mvan_0269|M.vanbaalenii_PYR-1 VGEELAEQLGTEPMHPVLMDLCTGVAFPAFPALLAAEQGVSDLFLPLRYG
Mflv_0405|M.gilvum_PYR-GCK VGAELAEQLGTEPMHPVLMDLCTGVAFPAFPALLAAEQGVNDLYLPLRYG
MSMEG_0408|M.smegmatis_MC2_155 VGAELAEQLGSEPMHPVLMDLCTGVAFPAFPALLAAEQGVNDLFLPLRYG
Rv1662|M.tuberculosis_H37Rv VPDDVDVTLSGFGIHPLVLD----AALHAMGMVGEQ----AATMLPFSWQ
Mb1690|M.bovis_AF2122/97 VPDDVDVTLSGFGIHPLVLD----AALHAMGMVGEQ----AATMLPFSWQ
MMAR_2472|M.marinum_M APEDATVQG--FGIHPAVLD----AALHAWGFATAT----DQLMLPFSWQ
MAV_3108|M.avium_104 LPEQAGVSTGRFGIHPVLLD----AALHALGVADKR----LETVLPFSWQ
MLBr_00135|M.leprae_Br4923 APTGVVVDG--MGMHPALLD----AVLHALGLAIENTQATTEMRLPFCWR
MUL_2005|M.ulcerans_Agy99 APSGVAVDK--MGMHPVVLD----AVLHALGLTAEQNPDSDETKLPFCWR
TH_4621|M.thermoresistible__bu LPGQIRSQQAPYGIHPALLD----ACFQSVAAHPDVQGAGSGLLLPLGVR
:** ::* . : : **:
MAB_0939|M.abscessus_ATCC_1997 QVTLKEKMPRRFYCRARWHESPLDSETQVFDLDYLDRDGRHLGGIREFTV
Mvan_0269|M.vanbaalenii_PYR-1 QVTLRDKMPRRFYCRATWHTSELDSETQVFDLDFLDRDGRHLGGIREFTV
Mflv_0405|M.gilvum_PYR-GCK QVSLQEKMPRRFYCRATWHEAPLDSETQVFDLEYLDRDGRHLGGVREFTV
MSMEG_0408|M.smegmatis_MC2_155 QVTLAEKMPRRFYCRARWHRSALDSETQVFELEFVDLGGRALGGIREFTV
Rv1662|M.tuberculosis_H37Rv GVSLHAAGASRVRARIAP------AGDGTVSVELADQAGLPVLSVQALVM
Mb1690|M.bovis_AF2122/97 GVSLHAAGASRVRARIAP------AGDGTVSVELADQAGLPVLSVQALVM
MMAR_2472|M.marinum_M GVSLHAAGAARLRVRITP------ADAGSVSLELADPRGLPVLSVKQLVV
MAV_3108|M.avium_104 GVSLHAAGASRVRVRLAP------AGAGAVSVELADASGVPVLSVRELVT
MLBr_00135|M.leprae_Br4923 GVSLHAGGAGRVRARFTS------AGADAIAVDIADSAGLPVLTVRSLVT
MUL_2005|M.ulcerans_Agy99 GVSLHAGGAGRVRARLTM------SGPDSISVEIADAAGLPVLTVGALVT
TH_4621|M.thermoresistible__bu RLQAFGPTRGARYCYARVTDAD--GSKAEADLDVLDEHGNVLLRVQGLLM
: . :: * * : : :
MAB_0939|M.abscessus_ATCC_1997 KRAPREALLRGLGGDATRLLYTLGWHEVAVPPVAGEGEESAASIGTWLIA
Mvan_0269|M.vanbaalenii_PYR-1 KRAPREALLRGLGGDATRLLYTLGWHEVPAPASG-----DAALNGNWLIA
Mflv_0405|M.gilvum_PYR-GCK KRAPREALLRGLGGDATRLLYTLGWHEVPVPESG----DGAAPQGTWLIG
MSMEG_0408|M.smegmatis_MC2_155 KRAPREALLRGLGGDATRLLYTLGWHEVPPPPSA------DDAVGTWLIA
Rv1662|M.tuberculosis_H37Rv RSVSSQLLSAAVAAADAA-------------------------GRGLLEV
Mb1690|M.bovis_AF2122/97 RSVSSQLLSAAVAAADAA-------------------------GRGLLEV
MMAR_2472|M.marinum_M RAVSGEALSAAVIAAGGTI------------------------SGRLLEV
MAV_3108|M.avium_104 RAVSAEQLAAAVAVRSG--------------------------SGELLDV
MLBr_00135|M.leprae_Br4923 RAMTAEQLRTAVTAAGG-AL-----------------------EQGPMDL
MUL_2005|M.ulcerans_Agy99 RAMSAAQLRAAVAEAGGGAP-----------------------DQGPLDV
TH_4621|M.thermoresistible__bu GGAAADGDDRDRVLGERLLTIEWQRRDLPEADSAAGKWLLVSTSATADVS
.
MAB_0939|M.abscessus_ATCC_1997 GFDELAAKVPGCIPLNRETDPELLGEVLVAAKERGVPFSGVVWRAAGPGA
Mvan_0269|M.vanbaalenii_PYR-1 GFDELAAGVPGCIPFDRSTDPEPLGQLLAQAHERGIGFSGVVWRAAAPSA
Mflv_0405|M.gilvum_PYR-GCK GFDELAVSVPGCIPADR-TNPESLRQLLTDAHGRGLPFSGVVWRAARSDG
MSMEG_0408|M.smegmatis_MC2_155 GFDELAAKVPGCVPIDRNTDLQVLGEVLSQAHARGAGFSGVVWRCATPGR
Rv1662|M.tuberculosis_H37Rv AWLPVE------------------------LAHNDISADLVVWEL-----
Mb1690|M.bovis_AF2122/97 AWLPVE------------------------LAHNDISADLVVWEL-----
MMAR_2472|M.marinum_M AWPPTSPELS--------------------ASDS--ARDVVVWES-----
MAV_3108|M.avium_104 AWSVIEPRNS--------------------LPDNPISEGVTVWEP-----
MLBr_00135|M.leprae_Br4923 VWSPIPLSSDGHGG-GLPSVVSWADYCAG----RGNDTGVVVWEFGSASA
MUL_2005|M.ulcerans_Agy99 IWSPIPLSGSGTNGSAQPAVVSWADFCAGGDGGAAGDAGVVVWEP-----
TH_4621|M.thermoresistible__bu ATRLSDALKQAGAESTSMCWPQQADHADNVDRFRAGIADGVTGVVVLTGP
. ..
MAB_0939|M.abscessus_ATCC_1997 TES--TTESAARLEGEIAHLLSAVHTVQNSAQNGVKLPGGLWIVTERAVA
Mvan_0269|M.vanbaalenii_PYR-1 DES--STAMAARIETEIADLLSAVHTVQN---GAVKLPGGLWIVTERAVA
Mflv_0405|M.gilvum_PYR-GCK DES--DAEVAARLEAEIAELLGAVHTVQG---GEVKLPGGLWIVTERAVA
MSMEG_0408|M.smegmatis_MC2_155 KESGSASAESARLEAEITNLLSAVHAAQG---PSVKLPGGLWIVTEHGVA
Rv1662|M.tuberculosis_H37Rv -ESFQDG-VGPVYSATHRVLVALQSWLAQ------ERAGRLVVLTQGSVG
Mb1690|M.bovis_AF2122/97 -ESFQDG-VGPVYSATHRVLVALQSWLAQ------ERAGGLVVLTQGSVG
MMAR_2472|M.marinum_M -GSADGD--VAVGQRVNEALAKLQSWLAG------DDPGVLVVLTRGAVG
MAV_3108|M.avium_104 -AAVDGAGPAAVHAATHQALGVLQSRLAG------EAGGVLVVSTRGAVG
MLBr_00135|M.leprae_Br4923 GAQAPVDSVAAVYSATHAALQVLQFWFGQ------DRAGTLVVLTRGAVG
MUL_2005|M.ulcerans_Agy99 -NPAGEDVVGPVYAATHAALEVLQSWFDG------DRAGTLVVLTHGAVA
TH_4621|M.thermoresistible__bu KNGNPDDAAARRGSDYVRHLVRITRELAEID----GDAPRLFVVTRGAQA
* * : *. . .
MAB_0939|M.abscessus_ATCC_1997 TESGEPVDPVQAALWGFGRTTINEEPALRAKLVDGDGSPEAVQALARLLV
Mvan_0269|M.vanbaalenii_PYR-1 TESGEPVDPVQAALWGFGRTTINEEPALRCRLVDVDGSPEAVLALAGLLA
Mflv_0405|M.gilvum_PYR-GCK TESGEPVDPVQAALWGFGRTAINEEPALRCRLVDCDGSPQAVQALAALLS
MSMEG_0408|M.smegmatis_MC2_155 CESGEPVDPVQAALWGFGRTTINEEPALHCRLVDCDGSSEAVDLLAALLA
Rv1662|M.tuberculosis_H37Rv ---QDATNLAGAAVWGLVRSAQAEHPG-RVMLVDSDGSMDVGDVIG----
Mb1690|M.bovis_AF2122/97 ---QDATNLAGAAVWGLVRSAQAEHPG-RVMLVDSDGSMDVGDVIG----
MMAR_2472|M.marinum_M LAGEGVTDLAGAAVWGLTRSAQAEHPG-RVVLVDTDDSVDIADAVA----
MAV_3108|M.avium_104 LPGEDVADLAGAAVWGLVRSAQAEHPG-RVVLVDTDGSLDLATVIG----
MLBr_00135|M.leprae_Br4923 LVGEGISDLAAAAVWGMVRSAQSEHSG-KIVLIDTDSAVDVAVLAD----
MUL_2005|M.ulcerans_Agy99 MPGENVSDLAGAAVWGIVRSAQAENPG-RIVLVDADAAVEAAELVA----
TH_4621|M.thermoresistible__bu VLPQDRPNLEQAGLRGLLRVIGAEHPHLRTTQIDIADDADLDRVAVQLLG
: *.: *: * *.. : :* :
MAB_0939|M.abscessus_ATCC_1997 TP-VDEPEIAVRQGKLLASRLLP----WSRTGHLTVPRGSD-YVLAPTER
Mvan_0269|M.vanbaalenii_PYR-1 AP-VDEPELAVRQGKLLASRLLP----WARSGHLTVPRSAD-YVLAPTER
Mflv_0405|M.gilvum_PYR-GCK TP-VDEPELAVRQGKLLASRLLP----WSRSGHLTVPRGGD-YVLAPTER
MSMEG_0408|M.smegmatis_MC2_155 APGIQEPEIAVRQGKLLASRLLP----WARSGHLTLPRGGD-FVLAPTER
Rv1662|M.tuberculosis_H37Rv ---CGEEQLMIRNGTAYAARLAQ----LRPQPILQLPDTNSGWRLVAGGA
Mb1690|M.bovis_AF2122/97 ---CGEEQLMIRNGTAYAARLAQ----LRPQPILQLPDTNSGWRLVAGGA
MMAR_2472|M.marinum_M ---CGEPQLVVRSGVVHGARLRF----IDSGSGLELPEGP--WRLAVGGG
MAV_3108|M.avium_104 ---CGEPQLVVRDGVAYRARLRP----AGRRALLELPGPPAVWRLAAGDA
MLBr_00135|M.leprae_Br4923 ---LGESQLLVRCNTVHAARLSP----APQ--LLALPVGESMWRLAADGG
MUL_2005|M.ulcerans_Agy99 ---VGEPQLVVRSGAAHAARLAP----AAP--LLAVPADESAWRLAAGGG
TH_4621|M.thermoresistible__bu GG--AEDETAWRDGQWYTARLSLSPLRPEERKQAVVDCERDGMRLEIRTP
* : * . :** : *
MAB_0939|M.abscessus_ATCC_1997 GAIDNLRITEKE--VPAPDEGYVQVRVEAAGLNFRDVLNVLGLYP---GD
Mvan_0269|M.vanbaalenii_PYR-1 GAIDNLRLTETD--VAPPAEGYVQVRVEAAGLNFRDVLNVLGLYP---GD
Mflv_0405|M.gilvum_PYR-GCK GAIDNLRLTDSE--VPPPAEGYVQVRVEAAGLNFRDVLNVLGLYP---GD
MSMEG_0408|M.smegmatis_MC2_155 GAIDNLRLTETD--VPEPDEGYVQVRVEAAGLNFRDVLNVLGLYP---GD
Rv1662|M.tuberculosis_H37Rv GALEDLTLASCP--AKELAPGQVRIEVRALGVNFRDVLVALGIYP---GA
Mb1690|M.bovis_AF2122/97 GTLEDLTLASCP--AKELAPGQVRIEVRALGVNFRDVLVALGIYP---GA
MMAR_2472|M.marinum_M GTLEDVLVQPCP--RADLAAGQVRVAVGAAGVNFRDVLVALGMYP---GG
MAV_3108|M.avium_104 GTLEDLAVQEHP--AAELAPGQVRVRVAAAGVNFRDVLVALGMYP---GA
MLBr_00135|M.leprae_Br4923 GTLEDLVIQPCPEVQAPLQAGHMRVAVAAVGVNFRDVVAALGMYP---GQ
MUL_2005|M.ulcerans_Agy99 GTLEDLVIEPCPEVQAPLAAGQVRVAVRAVGVNFRDVVAALGMYP---GA
TH_4621|M.thermoresistible__bu GDLETMELAAFD--RVPPGPGQIEVAVTASSINFADVLIAFGRYPTFDGR
* :: : : * :.: * * .:** **: .:* ** *
MAB_0939|M.abscessus_ATCC_1997 PGPIGGDFAGIVTQLGEGVTGVEVGQRVYGS-MQGAFGSRFNVPAQFLAP
Mvan_0269|M.vanbaalenii_PYR-1 PGPIGGDFAGTVTQLGSGVTGLEVGQRVYGF-MQGAFASRFNVPAQLLAP
Mflv_0405|M.gilvum_PYR-GCK PGPIGGDFAGTVTQLGEGVTGLDVGQRVYGS-MQGAFASRFNVPGQFLAP
MSMEG_0408|M.smegmatis_MC2_155 PGPIGGDFAGTVTQLGAGVSGLEIGQRVYGS-MQGAFASRFNVPAQFLAP
Rv1662|M.tuberculosis_H37Rv A-ELGAEGAGVVTEVGPGVTGLAVGDPVMG--LLGVAGSEAVVDARLVVK
Mb1690|M.bovis_AF2122/97 A-ELGAEGAGVVTEVGPGVTGLAVGDPVMG--LLGVAGSEAVVDARLVVK
MMAR_2472|M.marinum_M G-ALGAEGAGVVVEVGPGVEGLAVGDAVMG--LVGVVGSEAVVDERLVTT
MAV_3108|M.avium_104 A-QLGAEGAGVVTEVGAGVTDVAVGDAVMG--IFGLVGSEAAVDRRLVTR
MLBr_00135|M.leprae_Br4923 APPLGAEGAGVVIEIGPEVTGVAVGDAVMG--FLGGAGPLAVVHQQLITQ
MUL_2005|M.ulcerans_Agy99 APPLGAEGAGVVLEVGPQVSGVAVGDSVMG--FLGGAGPLSVVDQQLITR
TH_4621|M.thermoresistible__bu RPQLGTDFAGVVTAVGPDVTSHRVGDRVGGLSPNGCWSTFVTCDADLAVP
:* : ** * :* * . :*: * * * .. : .
MAB_0939|M.abscessus_ATCC_1997 IPDGISGVEAATIPAAALTVRLSF-DWAQLKPGDKVLIHAASGGVGLAAI
Mvan_0269|M.vanbaalenii_PYR-1 IPDGIGAVDAATIPAAALTARLAF-DWAQLKPGDRVLIHAASGGVGLAAI
Mflv_0405|M.gilvum_PYR-GCK IPDGVSAVEAATIPAAALTVRLSF-DWAQVKSGDKVLIHAASGGVGLAAV
MSMEG_0408|M.smegmatis_MC2_155 IPDGIGAVEAATIPAAALTVRLAF-DWAQLKPGDKVLIHAASGGVGLAAI
Rv1662|M.tuberculosis_H37Rv LPNRWPLTDAAGVPVVFLTAYYALRVLAQVQPGESVLVHAAAGGVGMAAV
Mb1690|M.bovis_AF2122/97 LPNRWPLTDAAGVPVVFLTAYCALRVLAQVQPGESVLVHAAAGGVGMAAV
MMAR_2472|M.marinum_M VPAGWSLAQAAGVPVVFLTAFYGLSVLAGLKAGERVLIHAGAGGVGMAAV
MAV_3108|M.avium_104 VPPGWSMAQAAGIPVVFLTAYYGLSVLAGLRAGQRVLVHAATGGVGMAAV
MLBr_00135|M.leprae_Br4923 MPQGWSLAEAAAVPVVFLTALFGLADLAGIRAGESVLIHAGTGGVGMAAV
MUL_2005|M.ulcerans_Agy99 MPQGWSFAQAAAVPVVFLTALFGLQDLAKIQPGESVLIHAGTGGVGMAAV
TH_4621|M.thermoresistible__bu LPDGLTEGQAAAVSTAHATAWYGLHDLARLGAGEKVLIHSATGGVGLAAI
:* :** :... *. .: * : .*: **:*:.:****:**:
MAB_0939|M.abscessus_ATCC_1997 QMAQQFGAEVFATAST-FKRATLRKLGVK--YVYDSRTTDFADQILADTD
Mvan_0269|M.vanbaalenii_PYR-1 QMAQQHGAVVFATAST-YKRATLRKLGVD--HVYDSRTTEFADQILADTD
Mflv_0405|M.gilvum_PYR-GCK QMAQQCGAEVYATAST-FKRATLRKLGVK--HVYDSRTTDFAEQILADTD
MSMEG_0408|M.smegmatis_MC2_155 QMAQQSGAEVFATAST-FKRSTLRRLGVK--YVYDSRTTDFADQILADTN
Rv1662|M.tuberculosis_H37Rv QLARLWGLEVFATASR-GKWDTLHTMGCDNTHVADSRTLAFEETFWLTTE
Mb1690|M.bovis_AF2122/97 QLARLWGLEVFATASR-GKWDTLHTMGCDNTHVADSRTLAFEETFWLTTE
MMAR_2472|M.marinum_M ALAKYWGAEIFVTASR-GKWDTLRAMGFDDEHIGDSRSLEFEEKFRKTSG
MAV_3108|M.avium_104 QLARHWGAEVFATASR-GKWDTLRAMGFDDAHIADSRTLDFEQKFGAAPG
MLBr_00135|M.leprae_Br4923 QFARHWGVEIFVTASR-GKWDTLRDMGFDDDHIGDSRTLEFEEKFLAVTD
MUL_2005|M.ulcerans_Agy99 QLARHWGVEIFVTASR-GKWDTLRAMGFDDDHIGDSRTLDFEEKFLAVTD
TH_4621|M.thermoresistible__bu AIARSVGAQIYATAGSPARRDLLRDMGIE--HVYDSRSTAFADEIRRDTD
:*: * ::.**. : *: :* . :: ***: * : : .
MAB_0939|M.abscessus_ATCC_1997 GAGVDVVLNSLTSEGFIEATLRATAKNGRFAEIAKRDIWTTEQM--AQSR
Mvan_0269|M.vanbaalenii_PYR-1 GEGVDVVLNSLTNEGFIEATVRATAQNGRFAEIAKRDIWTPEQM--AAAR
Mflv_0405|M.gilvum_PYR-GCK GAGVDVVLNSLTSEGFIEATLRATAQHGRFAEIAKRDIWTVEQM--AAAR
MSMEG_0408|M.smegmatis_MC2_155 GAGVDVVLNSLTSAGFVEATLKATAQGGRFAEIAKRDIWSHEQM--AEAR
Rv1662|M.tuberculosis_H37Rv GRGVDVVLNSLAGE-FTDASLRLLPRGGRFIEMGKTEFGTP---------
Mb1690|M.bovis_AF2122/97 GRGVDVVLNSLAGE-FTDASLRLLPRGGRFIEMGKTEFGTP---------
MMAR_2472|M.marinum_M GAGVDVVLNSLAGE-FTDASLRLLVSGGRFIEMGKTDLRDPQAV--ADEY
MAV_3108|M.avium_104 --GMDVVLNSLAGE-FNDASLRLLGPGGRFIEMGKTDLRDPDVV--ARAH
MLBr_00135|M.leprae_Br4923 GRGVDVVLDSLAGD-FVDASLRLLVRGGRFLEMGKTDIRDAQEI--AANY
MUL_2005|M.ulcerans_Agy99 GRGVDVVLDSLAGD-FVDASLRLLVRGGRFLEMGKTDIRDADKI--AANY
TH_4621|M.thermoresistible__bu GYGVDVVLNSLPGA-AQRAGLELLSFGGRFIEIGKRDIYGDTRLGLFPFR
*:****:**.. * :. *** *:.* ::
MAB_0939|M.abscessus_ATCC_1997 PDIAYEIVALDTVMFQEPDRIRVLLTEVSEGLAKG------EWTPLPAEI
Mvan_0269|M.vanbaalenii_PYR-1 PDIAYEIVALDTVTLLEPERIRGLLGEVSDGLGKADGSSRAEWVPLPAEI
Mflv_0405|M.gilvum_PYR-GCK PDLAYEIVALDTVMFTEPDRIRDLLTEVSAGLRDG------AWTPLPAEV
MSMEG_0408|M.smegmatis_MC2_155 PDIAYEIVALDTVMFTEPDRIRDLLTEVSDGMARG------EWTPLPAEI
Rv1662|M.tuberculosis_H37Rv --------------------------------------------------
Mb1690|M.bovis_AF2122/97 --------------------------------------------------
MMAR_2472|M.marinum_M PGVSYRAFDL---MEAGPDAIARMLSEVVGLLQEG------ILKAPPLKL
MAV_3108|M.avium_104 PGVRYRAFDL---MEAGPDRIAAMLAEVMELFAAG------ALTPLPVKA
MLBr_00135|M.leprae_Br4923 PGVQYRAFDL---SEAGPVRMQEMLCEVRELFDTQ------VLHRLPVTS
MUL_2005|M.ulcerans_Agy99 PGVWYRAFDL---SEAGPVRMQEMLAEVRELFDTA------VLHRLPVTT
TH_4621|M.thermoresistible__bu RNLAFHGVDLGLMADSHPHKIRELLETVYRLTADG------VLPMPQSTH
MAB_0939|M.abscessus_ATCC_1997 YPLTEARTAFRRMQQARHIGKIVCQMPNPLAPR---PDRTYLITGGLGAI
Mvan_0269|M.vanbaalenii_PYR-1 YPLTEARAAFRRMQQARHVGKIVLQMPKPLQPR---ADRSYLITGGLGAI
Mflv_0405|M.gilvum_PYR-GCK YPLTEARAAFRRMQQARHIGKIVVQIPNPLQPQ---PDRSYLITGGLGAI
MSMEG_0408|M.smegmatis_MC2_155 YPITEARSAFRRMQQARHIGKIVLQVPKPLQPQ---QDRSYLITGGLGAI
Rv1662|M.tuberculosis_H37Rv ----------------RSLPRTILGWPTGLST------------------
Mb1690|M.bovis_AF2122/97 ----------------RSLPRTILGWPTGLST------------------
MMAR_2472|M.marinum_M FDVRSAQQAYRYVSQARHIGKVVLTLPQGPAAQSVLSGGTVLITGGTGMA
MAV_3108|M.avium_104 FDARCAADAYRFVSAARHIGKVVLTMPDGPAG---LSGGTALITGATGMA
MLBr_00135|M.leprae_Br4923 WDVRCAPAAFRFMSQARHIGKVVLTMPSALADG--LAEGTVLITGASGAI
MUL_2005|M.ulcerans_Agy99 WDVRCAPAAFRFMSQARHIGKVVLTMPSALADG--LADATVLITGATGAV
TH_4621|M.thermoresistible__bu YPLAEAATAIRVMSAAEHVGKLVLDVPHTGRAD------VVVPPEQASPF
. : : : *
MAB_0939|M.abscessus_ATCC_1997 GLHTAAYLAQ-LGAGDIVLTSRRAPDTDAQRVIGEITERSKTRIHVFTAD
Mvan_0269|M.vanbaalenii_PYR-1 GLHTAAYLAQ-LGAGDLVLTSRRAPDADARRAIEEITERYKCRVHTFCAD
Mflv_0405|M.gilvum_PYR-GCK GLHTAGYLAQ-LGAGDIVLTSRRAPDAAAQQAIADIADRTKARLHVFTAD
MSMEG_0408|M.smegmatis_MC2_155 GLHTAAYLAQ-LGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAAD
Rv1662|M.tuberculosis_H37Rv --------------------------------------------------
Mb1690|M.bovis_AF2122/97 --------------------------------------------------
MMAR_2472|M.marinum_M GAAVARHLVQRYGVGHVVLVSRAGTQAPGIADLVAELQQGGAQVSVTACD
MAV_3108|M.avium_104 GAALARHLVARHRVPHLMLVGRRGEAAPGMAELAAELRGAGASVSVLSCD
MLBr_00135|M.leprae_Br4923 GGVLARHMVSAYGVRHLVLASRRGDRAEGAVELAAELVGAGAKIQVVACD
MUL_2005|M.ulcerans_Agy99 GAVLARHMLDGYGVRHLVLASRRGDRAEGAAELAAELSEAGANVQVVACD
TH_4621|M.thermoresistible__bu RSDGAYIVTGGMGGLGLYLAGEMAAAGAGCIVLNGRSAPSGEALRTIEQL
MAB_0939|M.abscessus_ATCC_1997 VGAESEVAGLLERIRAELPPLAGVAHLAGVLDDALLGQQSVERFRTTLAP
Mvan_0269|M.vanbaalenii_PYR-1 VGDESQVAELLARIRAELPPLAGVAHLAGVLDDALLSQQSLERFRTTLAP
Mflv_0405|M.gilvum_PYR-GCK VGVEADVAALLERIRAELPPLAGVAHLAGVLDDALLSQQSVERFRTALAP
MSMEG_0408|M.smegmatis_MC2_155 VGDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAP
Rv1662|M.tuberculosis_H37Rv --------------------------------------------------
Mb1690|M.bovis_AF2122/97 --------------------------------------------------
MMAR_2472|M.marinum_M VADRDAVAALLAQLPDRYP-LKGIFHAAGVLDDAVLASLTPDRVEPVLRA
MAV_3108|M.avium_104 VGDRDAVAAMLAQVPARYP-LRSVFHAAGVLDDAVIASLTPARIDTVLRA
MLBr_00135|M.leprae_Br4923 VADNDAVRGLFAQLSREFPPVRGVIHAAGVLDDGAITSLTPDRVDTVLRA
MUL_2005|M.ulcerans_Agy99 VADRDAVEAMLARLSGEYPPVRGVIHAAGVLDDAVISSLTPERIDTVLRA
TH_4621|M.thermoresistible__bu RAAGTEVIVECGXX-XRGQPVEVAVPTELRHADEHPDRRGAQLCDEFARG
MAB_0939|M.abscessus_ATCC_1997 KAFGAEYLDRLTKGDDLDFFIVSSSVSSLFGSPGQSNYATANALLDGLIA
Mvan_0269|M.vanbaalenii_PYR-1 KAFGACHLDRLTAGDDLDFFIMSSSVSSLFGSPGQANYATANALLDGLTA
Mflv_0405|M.gilvum_PYR-GCK KAFGAVHLDRLTRVDDLDFFLVSSSVSSLFGSPGQSNYATANAFLDGLVA
MSMEG_0408|M.smegmatis_MC2_155 KAYGASHLDRLTRDDDLDFFIVSSSVSSLFGSPGQANYATANAMLDGLVA
Rv1662|M.tuberculosis_H37Rv --------------------------------------------------
Mb1690|M.bovis_AF2122/97 --------------------------------------------------
MMAR_2472|M.marinum_M KAAGAWNLHELTHGMDLAAFVMFSSLAGIAGAPGQGNYAAANAFLDGLAA
MAV_3108|M.avium_104 KVDGAWNLHELTKDLDLSAFVVFSSMAGIVGAPGQGNYAAANSFLDALAI
MLBr_00135|M.leprae_Br4923 KVDAAWNLHEATRDLDLLMFVLCSSIAATVGSPGQGNYSAANAFLDGLAA
MUL_2005|M.ulcerans_Agy99 KVDAAWNLHEATLDLDLSMFVLCSSIAATVGSPGQGNYSAANSFLDGLAA
TH_4621|M.thermoresistible__bu EQGAQRNQHRTDAGEGQRDAHPPGAVGHDQPDPGALSDTGLDERGGQFPG
MAB_0939|M.abscessus_ATCC_1997 QRRAQGLPATGINFGPWGQGGMASS---EAATANISAQGLIPLDPSAALA
Mvan_0269|M.vanbaalenii_PYR-1 HRRARGLPATGVNFGPWAQGGMASS---EAATANIGAQGLVPLEPSAALG
Mflv_0405|M.gilvum_PYR-GCK QRRAQGLPATGVNFGPWARGGMASS---EAAAANISAQGLIPLEPSAALT
MSMEG_0408|M.smegmatis_MC2_155 KRRAQGLVATGINFGPWGQGGMASS---EAATANITAQGLIPLDPSAALH
Rv1662|M.tuberculosis_H37Rv --------------------------------------------------
Mb1690|M.bovis_AF2122/97 --------------------------------------------------
MMAR_2472|M.marinum_M YRRGQDLPAVSIAWGLWEQPSTMTQHLGDRDLARMRQVGLDPLSTEHALH
MAV_3108|M.avium_104 HRHAHGLPALSVAWGMWEEPSAMTAHLEERDKARMSRAGLSALSTRQALD
MLBr_00135|M.leprae_Br4923 YRQAAGLAGTSLAWGLWEQPGGMNAHLSSRDLARISRSGLAPMNPAQALE
MUL_2005|M.ulcerans_Agy99 HRQAAGLAGISVAWGLWEQSGGMAAHLSSRDLARMSRSGLAPMNPEQAVG
TH_4621|M.thermoresistible__bu VGVQIPVADPGVGIDHRG-----------AVRVDSGVPAQQGVDGEVVRH
MAB_0939|M.abscessus_ATCC_1997 ALAEVVANGTGQATILKAN-WQRAAKVLGSSRPPILDLVLPSAVGE----
Mvan_0269|M.vanbaalenii_PYR-1 ALAEVLANGTGQAAVLKAN-WQRAAKVLGSSRPPILDLVLPRPEGE----
Mflv_0405|M.gilvum_PYR-GCK AMAEVVANGTAQATVLKAN-WQRAAKVLGSSRPPILDLVLPSAVGE----
MSMEG_0408|M.smegmatis_MC2_155 ALAEVIANGSGQATVLKAN-WQRAAKVLGSARPPILDLVLPSAAGE----
Rv1662|M.tuberculosis_H37Rv --------------------------------------------------
Mb1690|M.bovis_AF2122/97 --------------------------------------------------
MMAR_2472|M.marinum_M LLDAALLGERPGVVAAQLNVAAL--SAN-PEVPPIWRDLVTRSVRR-VVD
MAV_3108|M.avium_104 LLDDALLGEQPLVVGTRLDRAAL--AQHRAALPPLLSELAGRPARR-MLE
MLBr_00135|M.leprae_Br4923 LFDAALVIDHPFMVTALLDRAALDAQAQAGALPPLFSRLVRRSRRRQIED
MUL_2005|M.ulcerans_Agy99 LLDAVLAINHPLMVATLLDRPALEARAQAGGLPPLFAGVVRRPRRRQIED
TH_4621|M.thermoresistible__bu RTLSSVRSGRSSRWTAPGSRCGSGRRYGGESCRRTTGPAAGAAARR----
MAB_0939|M.abscessus_ATCC_1997 ----VTGDSELLKQLMEIPVPQRAGFVTEFLQREVQNFLRLAQPPAATSR
Mvan_0269|M.vanbaalenii_PYR-1 ----VAGDSELLRQLQEIPVAQRAGFVTEFLQREVQNFLRLAQPPAATSR
Mflv_0405|M.gilvum_PYR-GCK ----ITGDSELLKQLQEIPVPQRAGFVTEFLQKEVQNFLRLAQPPAATSR
MSMEG_0408|M.smegmatis_MC2_155 ----ATGDSELLKQLMEIPIPQRAGFVTEFLQREVQNFLRLASPPAASSR
Rv1662|M.tuberculosis_H37Rv --------------------------------------------------
Mb1690|M.bovis_AF2122/97 --------------------------------------------------
MMAR_2472|M.marinum_M ANDNSASMTALISRLHTLSPEQRSRELVDMICTNAATVLGNAS-VDIDAN
MAV_3108|M.avium_104 HTD-MVSLTGLRARLAGMNPEQRQAELVELVCGNAAAVLGHST-ADVDPG
MLBr_00135|M.leprae_Br4923 PGDATQSKLALVQRLQGLAANRQLELLVGVVCLQAAAVLGRPSPEDIDPN
MUL_2005|M.ulcerans_Agy99 TGDAAQSKSALAERLNGLSAGERQDALVGLVCLQAAAVLGRPSPEDIDPE
TH_4621|M.thermoresistible__bu ------------GRTRRRRRPRRPPPPPDRVRHRAGPAHGPVRR------
MAB_0939|M.abscessus_ATCC_1997 --FLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVG
Mvan_0269|M.vanbaalenii_PYR-1 --FLDLGTDSLMAIELRNRLHSQFGGAFTINATAVFDYPTIGGLAEYLVG
Mflv_0405|M.gilvum_PYR-GCK --FLDLGTDSLMAIELRNRLHSQFGGAFTINATAVFDYPTIGGLAEYLVA
MSMEG_0408|M.smegmatis_MC2_155 --FLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVG
Rv1662|M.tuberculosis_H37Rv --------------------------------------------------
Mb1690|M.bovis_AF2122/97 --------------------------------------------------
MMAR_2472|M.marinum_M KPFQDLGFDSLTAVELRNRLKSSTG--LTLSPTLIFDYPTPAALAEHLST
MAV_3108|M.avium_104 DAFSDLGFDSLTAVELRNRLKIATG--LTLSPTVIFDHPTPAALAEHLGG
MLBr_00135|M.leprae_Br4923 TKFQDLGFDSLTAVELRNRLKSATG--LTLPPTVIFDHPTPTAVAEYVAQ
MUL_2005|M.ulcerans_Agy99 AGFQDLGFDSLTAVELRNRFKSATG--LTLPPTVIFDHPTPTAIAEYVGR
TH_4621|M.thermoresistible__bu --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 QLPDADAESAEAPPAVESAEAESGAGPAAASDAVSELKE-----------
Mvan_0269|M.vanbaalenii_PYR-1 QLPDSDAAAGETPATETSPIDHNHPDREADSPG-----------------
Mflv_0405|M.gilvum_PYR-GCK QLPD-----AETPQAAPQSESEPGPDVTE---------------------
MSMEG_0408|M.smegmatis_MC2_155 QLPD-----AEAPETA----------------------------------
Rv1662|M.tuberculosis_H37Rv --------------------------------------------------
Mb1690|M.bovis_AF2122/97 --------------------------------------------------
MMAR_2472|M.marinum_M QLSSLSPAAAD-----EQPNRLARFDAVARELDSMINEPDWTAEDRERVS
MAV_3108|M.avium_104 QLTSAGPTPAAPAETAAPPDRSSRIDEVVSELQTLLTQPGLSPGDRAQLV
MLBr_00135|M.leprae_Br4923 QMLKSRPAESGDETSQAVEPKVEEVSVHA---------------------
MUL_2005|M.ulcerans_Agy99 QIPDSQATQAEEE--KLPESDGEMVSVTA---------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 ----------------------------------------------
Mvan_0269|M.vanbaalenii_PYR-1 ----------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK ----------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155 ----------------------------------------------
Rv1662|M.tuberculosis_H37Rv ----------------------------------------------
Mb1690|M.bovis_AF2122/97 ----------------------------------------------
MMAR_2472|M.marinum_M NRLHGLLADLTSPQSRGE--DHSHDDDISSASESELFAILDEELGP
MAV_3108|M.avium_104 TRLQSLLSTPPQPSGHPEFPEDAFDDDIATATDSQLFAILDDEAGP
MLBr_00135|M.leprae_Br4923 ----------------------------------------------
MUL_2005|M.ulcerans_Agy99 ----------------------------------------------
TH_4621|M.thermoresistible__bu ----------------------------------------------