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M. vanbaalenii PYR-1 Mvan_1003 (-)

annotation: beta-ketoacyl synthase
coordinates: 1038535 - 1049625
length: 3696 

MTDLQKRALQAIEVLRARVRELEGAGDGYAIVGYALRFPGAADADEFWDVLRGGRDAISEVPQDRWDADE
FFDADPEAAGKMVTRRAGFVEDVAGFDAPFFGVSAREAMFMDPQHRLLLETAWRAVEHSGTAPSALAGTR
TGVFMGLSTHDYLGMLTDNLTHDAIEAYLGTGTSPAAAIGRISYRLGLQGPAVAVDTACSSSLVAVHQAC
QALRLAECDVALAGGVNVLLSPATMINFSRARMLAPDGRCKTFDATADGYVRGEGCGVVVVKRLADAIRH
GDRIRAVIRGSAVNQDGASGGLTVPNGAAQQRVIADALTNAGLTAADVDYLEAHGTGTPLGDPIEVQAAG
AVLGVGREPDRPLLIGSVKTNIGHLEAASGIAGLLKVILSLEHQVLPKHLNFRSPSPHIPWNRLPVRIVD
DPVPWTRSGRSRVAGISSFGFSGTNAHVLVEEAPRADRAGAAPQPAAPGGFGMLPLSARTPDALAATAHR
LRTWLAANPDASWPDLCFTAAVGRSHLRHRAALVVDSRSSVEELLGALAEDRPGPGLARGECGDPPKTAW
LFTGQGSQYPGMGRELFDTEPVYREVMTRCAEAVADVLERPLLDVVFDADGGEALRHTSYAQPALYAVEM
GLARLWQSWGIEPDVVLGHSVGQYAAACVAGVMGLEDGAVLLAERGRLFGSLPEGGRMAAVFAPADRVES
CTVDSPLLSVAAYNGDNTVLSGPAGDLERAVAGFSAAGVRCDWLDTSHAFHSALLDPVLEEFESCADRFE
FGTPQRTLVCNRSGEVLSRHARLDGQYWRRHARQPVRFAESVRTLADLGCRLLMEIGPQPVLTAAAMRTW
PGTVTAPRVAASMRRKGSDRRQITEALAQAYVAGHRPETAARQHGRGRLLDLPTYPFQHRAYWFPQGQAR
TAPTDPVHTETVRFLDEERIDELAALLDGPTGSAQTVDVLSKLAARHRQQRGAQSIADARYQIRWEKSEA
PGAARPTTEATTWLLVTHDSRAAQPIAEVLERRGHPYHIVGLPGSDADAAPAEEALRATVSQPRPHILYL
AALEEPGGSAAETLGWMQHRVLAAARRLFQLAATAGARAPIWLITAGAQRITGDETVEPAQTSLWGFGRA
AALEQPELWGGLADVTTGDAEEWSALIDHIVAAPTSEDQIAVRGREIHVARLTRCAEKANAAALELRREA
TYLVTGGLGALGLEVAEFLASHGAGHLVLTGRRSASDTVRQRIDAMRERFDCQVLVATADVADRDDVARL
FSTMRSELPPLAGIVHAAGEIGTSPLRTLDDAEMDRVFAGKVWGAVYLCEEVADMGLDFFLATSSIASVW
GSHGQTAYGAANAFLDGLADSLRARGIPGISVNFGPWAAGMADAKAREQLSRRGVKTLAPADALAGMADV
IAASTAHAVVARIDWATFLPVYQLQRRRAFLSQLEREVPDVPDASAPAPSGTTRFVEELTLAPVEQRRKL
VLEYLRAAVAEVTRVDAAEIRDEAGFFDLGMDSLMAIELRRRLEQGLGKELPVTLAMDHPHLSDAAEYVL
GDVLGLSEHTVAQPDTPSTVRTDDPIAIVGMACRFPGADDTDAFWSVLAEGADLIREIPDDRFDINEFYD
PDPEAAGKIYSRYGGFLDGVDGFDPEFFGISPREAVWIDPQQRLVLETAWEGLERAGYSAAALRGSRSGV
YVGVGANEYSHLLSGGSLDGIEAQFITGNALNVIAGRVSFTLGLEGPAVAVDTACSSSLVAVHQACQGLQ
SGDCDLALAGGVNVLLSPATTIATSRARMLSPDGRCKTFDAAADGYVRGEGCGILVLKRLSDAVRDGDRI
QAVIRGSAVNQDGASGGLTVPNGGAQQRVIAAALTRAGLSGSDIDYLEAHGTGTSLGDPIEVQAAGAVLG
AGRDPDRPLLMGSVKTNVGHLESASGVAGLIKVVLSLQHEMLPRHLHFKTPSPHIPWDRLAVRVVAEPTP
WRADGRPRRAGVSSFGFSGTNAHVVLEEPPAQSADLRQPPTDGKDGAAGLESATAPEPAGVLPISARSPE
ALTALARRYESWLTAHPDADIADVCYTAGAGRSHFEHRAALVVDSVDGARDLLAGLAEDRLGPGAVRGVC
GDPPKTAWLFTGQGSQYPGMARELFDTEPVFRDTVTRCAEAIGDTLPRPLLEVLFDTDGDNGQTLRHTSY
AQPALFAIEMGLARLWQARGIEPDVVLGHSVGQYAAACVAGVFGLEDGARLVADRGRLFGGLPVGGRMVA
VFTDAEVVEDFADEFPQVSVAAYNGPNTVLAGPASDLEQIVAGCSGEGIRTTWLDTSHAFHSALLDPVLD
EFESCAARLAYAAPTRPLVCNRTGAVVTGPGVIDAQYWRRHARQPVQFAESVRTLADLGCSVLMEIGPQP
FLIAAALRVWPESAATPRAIPSLRKGPDARRQLAEAVAAAYIAGHRLDFTGHDGGPHRRLPLPTYPFQHR
SYWPKTAGIRSDGSSGSGLLGSAQDLASGDIVHTSRLSVKTQPWLSDHVIYGTVVVPGATYAAMALAAMP
TPARVQEVFFYEPIILGDKDSREVQLMLHRTDDADGWTFEVHSRPYGDRDADWSRNASGTVAAGVGDAAP
DAAADPVDNAIERLTRTRPQQLFDAFADNDLAWGPAWCSSLRSLWVGTGEAVGDIAVGAELGEHLGREPI
HPVLLDLCTGIAGAALLAAAAQTDADPELFLPLRYGRVEVRERMPRRFYCRARWQTGGIDSETQVFDLDF
LDHDGRNLGGIREFTVKRAPREALLRGLGADATRLIYRVGWRETSPPVRDDGALGPSSTWLVAGLDALAD
DVPGSIRIGFDRIWDPDRDGRVVLDPADDEHWRRLFALADERRAPVAGVVLGVTGRARPEEPSADFAARL
EAQIRDVLGAVHSLSALGAKPAAGLWIVTERAVAAEAGEPVDPVQSALWGLGRTLIAEEPGLRCLLVDLD
GSEDAGPALARLLGAPGDEPELALRQGRLLVPRLLPWSRSGQLAIPRGTDYVLAPTERGVLDNLRVSETE
VTAPPEGHVQVRVEAAGLNFRDVLNALGLYPGDPGPIGGELAGVVTAPGPDVDGFDVGQRVFGFAVGAFA
SRVNVPVQFLAPVPEGISAVAAATTPAAVLTAGLAFDWAALRAGDRVLIHAASGGVGLAAVQLARQRGAT
VFATASGYKRPMLRAMGVDHVYDSRTTDFADQILADTDGAGVDVVLNSLTNDGFVAATVRATARNGRFAE
IAKRDIWSPEQMAAARPDIDYEVLALDAVMQQDPDRIQLLLADLADSLARGETAPLPFEAYPLAEATTAF
RRMQQARHTGKIILQMPKPLQPHGDRSYLITGGLGALGLHAAAYLAQLGAGDIVLTGRRMPDAATERAIS
EIAERYHCRIHTFAADVGDESAVRDLLERIRTELPPLAGVAHLAGVLDDALLPQQSPERFRTTLAPKAFG
AWHLHRLTRDTELEFFIVYSSGSSVLGSPGQANYATANAVLDGLVAHRKARGLPATGVNWGPWAQGGMAT
SDAARANLGAQGLIPLEPTAALNALGEIVAHGIASAVVLKANWQRAAKLLGATRPPILDHVLPSAVAAGP
GDSALLKQLQDVPEAQRGSFVTEHLQRELQQILGLAQPPAATGRFLELGMDSLMAVELRNRLVGQFGSGF
TITATAVFDYPTIGALAEYLAAQTPESTEEGTEMKTADPDGQPATVGHADVVLQTS

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. vanbaalenii PYR-1Mvan_1003--100% (3696)beta-ketoacyl synthase
M. vanbaalenii PYR-1Mvan_0269-0.068.65% (3700) beta-ketoacyl synthase
M. vanbaalenii PYR-1Mvan_1000-0.068.17% (933) amino acid adenylation domain-containing protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2074cpks120.037.00% (2546) polyketide synthase pks12
M. gilvum PYR-GCKMflv_0405-0.067.87% (3682) beta-ketoacyl synthase
M. tuberculosis H37RvRv2048cpks120.037.21% (2548) polyketide synthase pks12
M. leprae Br4923MLBr_00135-0.038.57% (2175) putative polyketide synthase
M. abscessus ATCC 19977MAB_0939-0.067.73% (3688) polyketide synthase
M. marinum MMMAR_3798-0.035.00% (3037) type I modular polyketide synthase
M. avium 104MAV_1763-0.069.23% (3705) tylactone synthase modules 4 & 5
M. smegmatis MC2 155MSMEG_0408-0.067.28% (3661) type I modular polyketide synthase
M. thermoresistible (build 8)TH_4621-0.035.11% (1854) PUTATIVE mycocerosic acid synthase
M. ulcerans Agy99MUL_2266pks120.036.60% (2549) polyketide synthase, Pks12

CLUSTAL 2.0.9 multiple sequence alignment


Mb2074c|M.bovis_AF2122/97           MVDQLQHATEALRKALVQVERLKRTNRALLERSSEPIAIVGMSCRFPGGV
Rv2048c|M.tuberculosis_H37Rv        MVDQLQHATEALRKALVQVERLKRTNRALLERSSEPIAIVGMSCRFPGGV
MUL_2266|M.ulcerans_Agy99           MVDQLQHATEALRKALVQVERLKRTKRALLERSSEPIAIVGMSCRFPGGV
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               -MENEERLRKYLQKAANDLRKSNKRVRELERRTVEPVAVVGMACRFPGGA
Mflv_0405|M.gilvum_PYR-GCK          -----------------------MGSAAHQGESAHRFAIVGYAGRFPG-A
MAB_0939|M.abscessus_ATCC_1997      -----------------------MDSAENPIESTPRFAIIGYAARFPG-A
MSMEG_0408|M.smegmatis_MC2_155      -----------------------MVSAEHPIEPTPSFAIIGYAARFPG-A
MAV_1763|M.avium_104                -----------------------MSTVEGLRDPASSFAIVGYAARFPG-A
Mvan_1003|M.vanbaalenii_PYR-1       --------MTDLQKRALQAIEVLRARVRELEGAGDGYAIVGYALRFPG-A
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           DSPEGLWQMVADARDVMSEFPTDRGWDLAGLFDPDPDVRHKSYARTGGFV
Rv2048c|M.tuberculosis_H37Rv        DSPEGLWQMVADARDVMSEFPTDRGWDLAGLFDPDPDVRHKSYARTGGFV
MUL_2266|M.ulcerans_Agy99           DSPEGLWQMVAEGRDVMSDFPTDRGWDLADLFDPDPDTPHKSYASTGGFV
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               DSPDGLWQMVSEGRDVLSEFPSDRGWDLGGLYDPEPDRVGYVHARAGGFL
Mflv_0405|M.gilvum_PYR-GCK          RDAESFWELLADGRDAISEVPEDR-WDVEAFFDPDPSTPGKVVTRRAGFV
MAB_0939|M.abscessus_ATCC_1997      ADAEEFWDVLREGRDAISEVPADR-WDAEEFFDPEPGAPGKVVTRRAGFV
MSMEG_0408|M.smegmatis_MC2_155      ASAEEYWALLRDGREAISDVPKDR-WDIEEFFDPDPSTPGKVVTRRAGFV
MAV_1763|M.avium_104                ADADEFWRVLAEGRDAVSEVPKDR-WDADEFFDPDPDAPGKVVTRRAGFV
Mvan_1003|M.vanbaalenii_PYR-1       ADADEFWDVLRGGRDAISEVPQDR-WDADEFFDADPEAAGKMVTRRAGFV
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           DGVADFDPAFFGISPSEALAMDPQHRMLLELSWEALERAGIDPTGLRGSA
Rv2048c|M.tuberculosis_H37Rv        DGVADFDPAFFGISPSEALAMDPQHRMLLELSWEALERAGIDPTGLRGSA
MUL_2266|M.ulcerans_Agy99           DGVADFDPGFFGIAPSEALAMDPQHRMLLELSWEALERSGIDPTGLRGSA
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               DGVADFDAGFFGISPREALGMDPQQRLILEIAWETLESASIDPQSLRGSQ
Mflv_0405|M.gilvum_PYR-GCK          DDVSGFDAPFFGMSTREVRLMDPQHRLLLETAWRAIEHSGTAPSELANTN
MAB_0939|M.abscessus_ATCC_1997      EDVTGFDAPFFGMSTREVRLMDPQHRLLLETAWRAVEHSGIAPTDLAETN
MSMEG_0408|M.smegmatis_MC2_155      DDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSN
MAV_1763|M.avium_104                DDVTGFDAPFFGMSAREARLLDPQHRLLLETAWRAVEHSGTAPTDLANTN
Mvan_1003|M.vanbaalenii_PYR-1       EDVAGFDAPFFGVSAREAMFMDPQHRLLLETAWRAVEHSGTAPSALAGTR
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           TGVFAGLIVGGYG------MLAEEIEGYRLTGMTSSVASGRVAYVLGLEG
Rv2048c|M.tuberculosis_H37Rv        TGVFAGLIVGGYG------MLAEEIEGYRLTGMTSSVASGRVAYVLGLEG
MUL_2266|M.ulcerans_Agy99           TGVFAGLIVQGYG------MFAEEIEGYRLTGMTSSVASGRVAYVLGLEG
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               TGVFAGTMTSCYG------VGIDNVT---------SAVSGRVAYAFGFEG
Mflv_0405|M.gilvum_PYR-GCK          TGVFVGLATHDYLGMASDELSYPEIEAYMAIGTSNAAAAGRISYRLGLQG
MAB_0939|M.abscessus_ATCC_1997      SGVFVGLATHDYLGMASDELTFPEIEAYMAIGTSNAAAAGRISYRLGLQG
MSMEG_0408|M.smegmatis_MC2_155      TGVFVGLATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQG
MAV_1763|M.avium_104                TGVFIGISTHDYLGMASDELTYDQIEAYTAIGTSSAAAAGRISYRLGLQG
Mvan_1003|M.vanbaalenii_PYR-1       TGVFMGLSTHDYLGMLTDNLTHDAIEAYLGTGTSPAAAIGRISYRLGLQG
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           PAVSVDTACSSSLVALHMAVGSLRSGECDLALAGGVTVNATPTVFVEFSR
Rv2048c|M.tuberculosis_H37Rv        PAVSVDTACSSSLVALHMAVGSLRSGECDLALAGGVTVNATPTVFVEFSR
MUL_2266|M.ulcerans_Agy99           PAVSVDTACSSSLVALHMAVQSLRSGECDLALAGGATVNATPTVFVEFSR
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               PAVTVDTACSSSLVAIHQACQSLRGGECSMALAGGVTVMATPDVFAEFAR
Mflv_0405|M.gilvum_PYR-GCK          PAVAVDTACSSSLVAIHQACQALRLGECDLALAGGANVILTPATMITFSN
MAB_0939|M.abscessus_ATCC_1997      PSVAVDTACSSSLVAIHQACQALQLGECDLALAGGANVLLTPATMITFSH
MSMEG_0408|M.smegmatis_MC2_155      PAVAVDTACSSSLVAIHQACQALRLNECDLALAGGANVLLTPATMITFSN
MAV_1763|M.avium_104                PAVAVDTACSSSLVAIHQACQALRLGECDLALAGGANVLLTPATMITFSQ
Mvan_1003|M.vanbaalenii_PYR-1       PAVAVDTACSSSLVAVHQACQALRLAECDVALAGGVNVLLSPATMINFSR
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           HRGLAPDGRCKPYAGRADGVGWSEGGGMLVLQRLSDARRLGHPVLAVVVG
Rv2048c|M.tuberculosis_H37Rv        HRGLAPDGRCKPYAGRADGVGWSEGGGMLVLQRLSDARRLGHPVLAVVVG
MUL_2266|M.ulcerans_Agy99           HRGLAPDGRSKAYAGAADGVGWSEGGAMLVVERLSDAQRLGHPVLALVRG
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               QRGLSADGRCKAFAASADGTGFGEGAGLVLLERLSDARRNRHPVLAVIRG
Mflv_0405|M.gilvum_PYR-GCK          AHMLAPDGRCKTFDAAADGYVRGEGCGVIVIKRLEDAVRDGDRIRAVIRG
MAB_0939|M.abscessus_ATCC_1997      AHMLAPDGKCKTFDAAADGYVRGEGSGVIVIKRLEDAIRDGDRIRAVIRG
MSMEG_0408|M.smegmatis_MC2_155      AHMLAPDGRCKTFDAAADGYVRGEGCGVVVVKRLEDAVRDGDRIRAVIRG
MAV_1763|M.avium_104                AHMLAPDGRCKTFDAAADGYVRGEGCGVLVVKRLEDAIRDGDRIRAVIRG
Mvan_1003|M.vanbaalenii_PYR-1       ARMLAPDGRCKTFDATADGYVRGEGCGVVVVKRLADAIRHGDRIRAVIRG
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           SAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTTL
Rv2048c|M.tuberculosis_H37Rv        SAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTTL
MUL_2266|M.ulcerans_Agy99           SAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTTL
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               SAVNQDGASNGLTAPNGPAQERVIRSAVAAAGLRVADVDVVEAHGTGTTL
Mflv_0405|M.gilvum_PYR-GCK          SAINQDGASGGLTVPNGVAQQRVIGDALSRAGLAPGDVDYLEAHGTGTSL
MAB_0939|M.abscessus_ATCC_1997      SAINQDGASGGLTVPNGVAQQRVIADALKRAGVAPSEVGYLEAHGTGTSL
MSMEG_0408|M.smegmatis_MC2_155      SAINQDGASGGLTVPNGVAQQRVIADALKRAGLRPADVGYLEAHGTGTSL
MAV_1763|M.avium_104                SAINQDGASGGLTVPNGVAQQRVIAEALQRAGIAPGDVDYLEAHGTGTSL
Mvan_1003|M.vanbaalenii_PYR-1       SAVNQDGASGGLTVPNGAAQQRVIADALTNAGLTAADVDYLEAHGTGTPL
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           GDPIEAQALLATYGQDRGEP---GEPLWLGSVKSNMGHTQAAAGVAGVIK
Rv2048c|M.tuberculosis_H37Rv        GDPIEAQALLATYGQDRGEP---GEPLWLGSVKSNMGHTQAAAGVAGVIK
MUL_2266|M.ulcerans_Agy99           GDPIEAQALLATYGQDRGSAGAAGKALWLGSIKSNMGHTQAAAGVAGVIK
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               GDPIEAHALLATYGADRDAE----QPLWLGSVKSNMGHTQAAAGVAGLIK
Mflv_0405|M.gilvum_PYR-GCK          GDPIEAQAAGAALGPGREPQ----RPLLIGSAKTNIGHLEAAAGIAGVIK
MAB_0939|M.abscessus_ATCC_1997      GDPIEAQAAGAAYGIGRETN----DPLLIGSAKTNIGHLEAAAGIAGVIK
MSMEG_0408|M.smegmatis_MC2_155      GDPIEAQAAGEVLGAGRAPE----EPLLIGSAKTNIGHLEAAAGIAGVIK
MAV_1763|M.avium_104                GDPIEVQAAGAVLGAGREAS----RPLLIGSVKTNIGHLEAAAGIAGVIK
Mvan_1003|M.vanbaalenii_PYR-1       GDPIEVQAAGAVLGVGREPD----RPLLIGSVKTNIGHLEAASGIAGLLK
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           MVLAMRHELLPATLHVDVPSPHVDWSAGAVELLTAPRVWP---AGARTRR
Rv2048c|M.tuberculosis_H37Rv        MVLAMRHELLPATLHVDVPSPHVDWSAGAVELLTAPRVWP---AGARTRR
MUL_2266|M.ulcerans_Agy99           MVQAMRHEVLPATLHVDVPSPHVDWSAGAVELLTEAQPWPAESAGDRVRR
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               MIQAINHAVLPPTLHVDAPSPHIDWSAGAVRLLTEAVPWP---DTGRART
Mflv_0405|M.gilvum_PYR-GCK          VVLSLEHETLPKHLNFENPSPHIPWDRLPVEVVKESIPWRRGQRGGRPRI
MAB_0939|M.abscessus_ATCC_1997      VILSLENELLPQHRNFQNPSPHIPWDRLPVEVVREARPWGR---NGRPRI
MSMEG_0408|M.smegmatis_MC2_155      VVMALENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQR---NGKPRI
MAV_1763|M.avium_104                VILALEHGMLPQHLHFRDPSPHIPWDRLAVQVVKEATAWQR---NGRPRV
Mvan_1003|M.vanbaalenii_PYR-1       VILSLEHQVLPKHLNFRSPSPHIPWNRLPVRIVDDPVPWTR---SGRSRV
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           AGVSSFGISGTNAHVIIEAVP---VVPRR-EAGW----AGPVVPWVVSAK
Rv2048c|M.tuberculosis_H37Rv        AGVSSFGISGTNAHVIIEAVP---VVPRR-EAGW----AGPVVPWVVSAK
MUL_2266|M.ulcerans_Agy99           AGVSSFGISGTNAHVIVEAAP---RVEVGGSSGG----AVPVVPWVVSAK
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               AGISSFGISGTNAHLIAQEAPQESTADPSPSDVC----EPLFRVWPVSGR
Mflv_0405|M.gilvum_PYR-GCK          AGVSSFGFAGTNAHVILEEAPLAAEPAQES------VDDGRFTLLPLSAR
MAB_0939|M.abscessus_ATCC_1997      AGVSSFGFAGTNAHVILEEAPVVSRDAVEPPA---PAGGRKFSILPLSAR
MSMEG_0408|M.smegmatis_MC2_155      AGVSSFGFAGTNAHVILEEAPAVGTPATTEP----VEDPRRYSVLPLSAR
MAV_1763|M.avium_104                AGVSSFGFAGTNAHVILEEAPDGTGRAAVPPAAVRPPGQRRFHVLPLSAR
Mvan_1003|M.vanbaalenii_PYR-1       AGISSFGFSGTNAHVLVEEAPRADRAGAAPQP----AAPGGFGMLPLSAR
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           SESALRGQAARLAAYVRGDDGLDVADVGWSLAG-RSVFEHRAVVVGG---
Rv2048c|M.tuberculosis_H37Rv        SESALRGQAARLAAYVRGDDGLDVADVGWSLAG-RSVFEHRAVVVGG---
MUL_2266|M.ulcerans_Agy99           SGSALGAQAARLAAHVRSHDELDVADVGWSLAG-RSTFEHRAVVLGA---
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               TAEALNAQAERLGQYLVDHPDLDLTDLAYSLATTRAHHAYRAAVTVPGDT
Mflv_0405|M.gilvum_PYR-GCK          TPAALMAVADRYRDWLVANPDATLADLCFTAGTARSHLEHRAALVVN---
MAB_0939|M.abscessus_ATCC_1997      TPAALAQLADKYRAWLNAHPEAALADLCFTAGVGRAHLEHRAALVVN---
MSMEG_0408|M.smegmatis_MC2_155      TPEALVRLAGEYRDWLRAHPQARLADVSHTAGTARAHLEQRAALVVN---
MAV_1763|M.avium_104                TPAALVQIAGEYRDWLSAHPDTALADLCLTAGAGRAHFEHRAALVVD---
Mvan_1003|M.vanbaalenii_PYR-1       TPDALAATAHRLRTWLAANPDASWPDLCFTAAVGRSHLRHRAALVVD---
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           --DRDRLLAGLDELAGDQLG-GSVVRGTAT-AAGKTVFVFPGQGSQWLGM
Rv2048c|M.tuberculosis_H37Rv        --DRDRLLAGLDELAGDQLG-GSVVRGTAT-AAGKTVFVFPGQGSQWLGM
MUL_2266|M.ulcerans_Agy99           --DRDGLLAGLDELAGDEFGGASVIRGVAG-AAGKTVFVFPGQGSQWIGM
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               VNTRDDLLAGLRSLAVDQFHPGVTYHHYRLGQAGKTVFVFPGQGAQYAGM
Mflv_0405|M.gilvum_PYR-GCK          --TREAALDLLGALADDRPAPGLVRGESHD--TPKTAWLFTGQGSQYPGM
MAB_0939|M.abscessus_ATCC_1997      --TREAAVELLSAVADDRPAPGLGRGESHD--TPKTAWLFTGQGSQYPGM
MSMEG_0408|M.smegmatis_MC2_155      --SRESAIELLGALADDRPAPGLVRGESHE--APKTAWLFTGQGSQYPGM
MAV_1763|M.avium_104                --STGSAGELLAALADDRPAPGLLRGVCED--APKTAWLFTGQGSQYAGM
Mvan_1003|M.vanbaalenii_PYR-1       --SRSSVEELLGALAEDRPGPGLARGECGD--PPKTAWLFTGQGSQYPGM
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           GIELLDTAPAFAQQIDACAEAFAEFVDWSLVDVLRGAPGA------PGLD
Rv2048c|M.tuberculosis_H37Rv        GIELLDTAPAFAQQIDACAEAFAEFVDWSLVDVLRGAPGA------PGLD
MUL_2266|M.ulcerans_Agy99           GIELLDTAPVFARHIESCGQAFAEFVDWSLLDVLRGAAGA------PGLD
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               GAGLYRHHPVFTTAIDEICAVMDEHLDVPLRDVMFTEPG--------LLQ
Mflv_0405|M.gilvum_PYR-GCK          SRELFDTEPLFAETLRECAAAVDGMLEKPLLDVIFDTDGVLDTDSNETLR
MAB_0939|M.abscessus_ATCC_1997      ARELFETEPVFADTLNRCAAAVADVLEKPLLDVIFDVD---GPEAEETLR
MSMEG_0408|M.smegmatis_MC2_155      ARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDAD-ELDGDTESPLR
MAV_1763|M.avium_104                ARELFDTEPVFAETLTRCATVLADVLEKPLLDVIFDTD---DPASEATLR
Mvan_1003|M.vanbaalenii_PYR-1       GRELFDTEPVYREVMTRCAEAVADVLERPLLDVVFDAD------GGEALR
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           RVDVVQPVLFAVMVSLAELWKSVAVHPDAVIGHSQGEIAAAYVAGALSLR
Rv2048c|M.tuberculosis_H37Rv        RVDVVQPVLFAVMVSLAELWKSVAVHPDAVIGHSQGEIAAAYVAGALSLR
MUL_2266|M.ulcerans_Agy99           RIDVVQPVLFAVMVSLAELWKSVGVRPDAVIGHSQGEIAAAYVAGALSLR
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               QTVYAQPALFAFGVAMHAVLTQAGVNPDYLLGHSVGELTAAHVAGVLSLE
Mflv_0405|M.gilvum_PYR-GCK          HTSYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVGQYAAACVAGVLSLR
MAB_0939|M.abscessus_ATCC_1997      QTSYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVGQYSAACVAEVFSLE
MSMEG_0408|M.smegmatis_MC2_155      HTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVE
MAV_1763|M.avium_104                QTSYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVGQYSAACVAGVLRVE
Mvan_1003|M.vanbaalenii_PYR-1       HTSYAQPALYAVEMGLARLWQSWGIEPDVVLGHSVGQYAAACVAGVMGLE
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           DAARVVTLRSKLLAGLAGPGGMVSIACGADQARDLLAPFGDRVSIAVVNG
Rv2048c|M.tuberculosis_H37Rv        DAARVVTLRSKLLAGLAGPGGMVSIACGADQARDLLAPFGDRVSIAVVNG
MUL_2266|M.ulcerans_Agy99           DAAKVVTLRSKLLVGLAGPGGMVSVACGEQQARELLEPFGDRVSIAAING
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               EAAVLVCARGRLMQSCT-PGAMMAISASEPAVAAMLENH-PEVVIAAVNG
Mflv_0405|M.gilvum_PYR-GCK          DGARLMAERGRLFGSLPSGGRMAAVFAAAERVEALTDEYPALSVAAYNG-
MAB_0939|M.abscessus_ATCC_1997      DGARLIAERGRLFSSLPAGGRMAAVFTDAERAERLTDEFPSLSVAAYNG-
MSMEG_0408|M.smegmatis_MC2_155      DGARLIAERGRLFGSLPAGGRMAAVFTAPERAERLTDEYPSLSVAAYNG-
MAV_1763|M.avium_104                DGARLIAERGRLFGSLPAGGRMVAAFAAAARVEGLTDEFPSLSVAAYNG-
Mvan_1003|M.vanbaalenii_PYR-1       DGAVLLAERGRLFGSLPEGGRMAAVFAPADRVESCTVDSPLLSVAAYNG-
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           PSAVVVSGEVGALEELIAVCSTKELRTRRIEVDYASHSVEVEAIRGPLAE
Rv2048c|M.tuberculosis_H37Rv        PSAVVVSGEVGALEELIAVCSTKELRTRRIEVDYASHSVEVEAIRGPLAE
MUL_2266|M.ulcerans_Agy99           PSAVVVSGEVAALEELIAQCADRELRTRRIDVDYASHSVEVEAIEGQLTE
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               PTSVAVAGPAEQLNALREHCNISNHKVTLLRVSHAFHSPAMDPILAEFEA
Mflv_0405|M.gilvum_PYR-GCK          -ANTVLSGPATDLERAVAGLVADGVRCDWLETSHAFHSALLDPILDDFES
MAB_0939|M.abscessus_ATCC_1997      -ANTVLSGPAQDLEKAIAALVADGVRCDFLETSHAFHSALLDPILDEFEA
MSMEG_0408|M.smegmatis_MC2_155      -ANTVLSGPAKDLESAVATLVADGVRCDWLDTSHAFHSALLDPILDDFES
MAV_1763|M.avium_104                -ANTVLSGPGQELEQAVARLTAEKVRCDWLDTSHAFHSALLDPILDEFES
Mvan_1003|M.vanbaalenii_PYR-1       -DNTVLSGPAGDLERAVAGFSAAGVRCDWLDTSHAFHSALLDPVLEEFES
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           ALSGIEPRSTRTVFFSTVTGNRLDTAGLD-ADYWYRNVRQTVLFDQAVRN
Rv2048c|M.tuberculosis_H37Rv        ALSGIEPRSTRTVFFSTVTGNRLDTAGLD-ADYWYRNVRQTVLFDQAVRN
MUL_2266|M.ulcerans_Agy99           VLAGIEPLSSRTAFFSSVTGSRLDTAELD-AEYWYRNIRQTVQFDQAVRS
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               IAKRLTYRPHSVPIMSNLTGSLATVEQLTSARYWAQHLRKPVRFYDGVTR
Mflv_0405|M.gilvum_PYR-GCK          YARGITFTAPQRILIDNRTGAALGRSVTLDAAYWRRHARQPVEFAKSVHT
MAB_0939|M.abscessus_ATCC_1997      YANQFNYKTPQRILIDNRTGTALGRSVKLDGAYWRRHARQPVEFAKSVRT
MSMEG_0408|M.smegmatis_MC2_155      FAQKLEYREPQRILIDNRTGSALGRSTRLDGAYWRRHARQPVEFAKSVRT
MAV_1763|M.avium_104                YANQFDFGPPQRILICNRTGSALGRSVKLDGAYWRRHARQPVEFAKSVHT
Mvan_1003|M.vanbaalenii_PYR-1       CADRFEFGTPQRTLVCNRSGEVLSRHARLDGQYWRRHARQPVRFAESVRT
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           ACEQGYRTFIESSPHPALITGVEETFAACTDGD-SEAIVVPTLGRGDGGL
Rv2048c|M.tuberculosis_H37Rv        ACEQGYRTFIESSPHPALITGVEETFAACTDGD-SEAIVVPTLGRGDGGL
MUL_2266|M.ulcerans_Agy99           ACGHGYRTFIESSPHPALIAGIEDTYRNCAADSGADPIVVPTLGREDGGL
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               LLAGGEQAFVELSPHPVLAAAITDTLTG--VTDRVGSAVVTTLRRDRPDM
Mflv_0405|M.gilvum_PYR-GCK          LADMNCKLLVEIGPRPVLTAAALSAWPDPATSP----RVIASLRRTTADQ
MAB_0939|M.abscessus_ATCC_1997      LADMNCKVLLEIGPQPVLTAAALRAWPDPATAP----RAIASLRRNTADH
MSMEG_0408|M.smegmatis_MC2_155      LADMNCRVLLEIGPRPVLTATALAAWPDPATTP----QVLASLRPTTADH
MAV_1763|M.avium_104                LADLGCKVLLEIGPQPVLTAAALRAWPDPATAP----RAIASLRRNTADH
Mvan_1003|M.vanbaalenii_PYR-1       LADLGCRLLMEIGPQPVLTAAAMRTWPGTVTAP----RVAASMRRKGSDR
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           HRFLLSAASAFVAGVAVNWRGTLD-GAGYVELPTYAFDKRRFWLSAEGSG
Rv2048c|M.tuberculosis_H37Rv        HRFLLSAASAFVAGVAVNWRGTLD-GAGYVELPTYAFDKRRFWLSAEGSG
MUL_2266|M.ulcerans_Agy99           QRFLASAAAAFVAGVNVDWRGPLD-GAGLVELPTYAFEKRRFWLSGEGVS
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               DMVASAIANLHVHGHSPSWQKIYP-GATTVELPTYPFQHRRYWLDP-APR
Mflv_0405|M.gilvum_PYR-GCK          RQITEAVADAYVLGHLPRFAAFRRDGARVLDLPTYPFEHRQYWFSDSRE-
MAB_0939|M.abscessus_ATCC_1997      RQITEAAADAYVLGHLPDFGAFQHAPARKLDLPTYPFERRQYWFSDKRDG
MSMEG_0408|M.smegmatis_MC2_155      RQITEAVAAAYAAGHLPDFRAFRQPDARKLDLPTYPFEHRQFWFSDNRAI
MAV_1763|M.avium_104                RQITEALAEAYIVGHLPDFGAAVG-PARKLDLPTYPFQHRQYWFSEQRVP
Mvan_1003|M.vanbaalenii_PYR-1       RQITEALAQAYVAGHRPETAARQHGRGRLLDLPTYPFQHRAYWFPQGQAR
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           ADVSGLGLGASEHPLLGAVVDLPASGGVVLTGRLSPNVQPWLADHAVSDV
Rv2048c|M.tuberculosis_H37Rv        ADVSGLGLGASEHPLLGAVVDLPASGGVVLTGRLSPNVQPWLADHAVSDV
MUL_2266|M.ulcerans_Agy99           VDASGLGLSAGGHALLGAVVELPESGGVVLTGRLALGAHGWLADHAVSGV
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               ADVSAAGLDQPEHPLLAAVTELADQDQIVLSGRLSTSAHRWLAGHQLGDT
Mflv_0405|M.gilvum_PYR-GCK          --PVAAAPQR---GARTETVRLLEDG------------------------
MAB_0939|M.abscessus_ATCC_1997      DNRDAGNRQQNNGGPRTEAVRLLEDG------------------------
MSMEG_0408|M.smegmatis_MC2_155      DRDTQTASAGSVTPHRTQAVRLLEDG------------------------
MAV_1763|M.avium_104                PGSQQT-------STQTTAVRLLEDG------------------------
Mvan_1003|M.vanbaalenii_PYR-1       TAPTDP--------VHTETVRFLDEE------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           VLFPGTGFVELAIRAGDEVGCSVLDELTLAAPLLLPATGSVAVQVVVDAG
Rv2048c|M.tuberculosis_H37Rv        VLFPGTGFVELAIRAGDEVGCSVLDELTLAAPLLLPATGSVAVQVVVDAG
MUL_2266|M.ulcerans_Agy99           VVFPGTGFVELAIRAVDEVGCSVVNELTLRTPLVLPASGSVAVQVVVGAA
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               VVLPATALIDMALYAGEHTGCPTIDELVLQTPLTLTPDAATDLQISVAAP
Mflv_0405|M.gilvum_PYR-GCK          ----------------------RIEELAALLGGTVDDPFTFDVLNRLAAQ
MAB_0939|M.abscessus_ATCC_1997      ----------------------KIEELANLLGGVDGDQQTLNVLTKLAAQ
MSMEG_0408|M.smegmatis_MC2_155      ----------------------QIEELAALIDGETVDEQTLRVLNKLAAR
MAV_1763|M.avium_104                ----------------------RIAELAELLDGASADQHTLDVLTKLAAQ
Mvan_1003|M.vanbaalenii_PYR-1       ----------------------RIDELAALLDGPTGSAQTVDVLSKLAAR
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           RDSNSRGVSIFSRADAQAG------WLLHAEGILRPGSVEPGADLSVWPP
Rv2048c|M.tuberculosis_H37Rv        RDSNSRGVSIFSRADAQAG------WLLHAEGILRPGSVEPGADLSVWPP
MUL_2266|M.ulcerans_Agy99           ADSAERSVSIYSRTDTDTDTDAGSVWVCHAEGTLGADSAQPAADLSAWPP
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               DEQNRRTFSVHARTSEHPHQHS--TWVLHASGTLSNAPSTTPPTKPLPGP
Mflv_0405|M.gilvum_PYR-GCK          HNQQRSTESIADDR-----------YQIRWETAAEPPVGADAADGITWLL
MAB_0939|M.abscessus_ATCC_1997      HNLQRTTQTIADDR-----------YQFRWEKSPTPLSGSQAAGGVTWLL
MSMEG_0408|M.smegmatis_MC2_155      HNQQRSTHVDPDAR-----------YEIRWDAIASAAASTGAAA--DWIL
MAV_1763|M.avium_104                HNQQRKSRSIAEDR-----------YEIRWEKSTVPG----PEAEATWLV
Mvan_1003|M.vanbaalenii_PYR-1       HRQQRGAQSIADAR-----------YQIRWEKSEAPGAARPTTEATTWLL
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           AGAVTVDVADGYERLATRGYRYGPAFRGLTAMWAR---GEEIFAEVRLPE
Rv2048c|M.tuberculosis_H37Rv        AGAVTVDVADGYERLATRGYRYGPAFRGLTAMWAR---GEEIFAEVRLPE
MUL_2266|M.ulcerans_Agy99           AGAIAVDVADGYERLDARGYGYGPAFRGLTAMWAR---GEELFAEARLPE
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               QAITKVNQESFYDQLAQHGLHYSEAFRSIQGIGKDPLNPDAICAEVALPA
Mflv_0405|M.gilvum_PYR-GCK          VGDDTDATRPLVDVLAARGHRYRILGLPKSGAEEH---------------
MAB_0939|M.abscessus_ATCC_1997      VADAAGAAQPLLDVLTARGQQHRVLALPVSDADEA---------------
MSMEG_0408|M.smegmatis_MC2_155      VGDDTAAVLEFADALTAGGHRHQIVALPGSDADEA---------------
MAV_1763|M.avium_104                VGDDDDAVAPLVDALTARGHQHRILVLPASDADEE---------------
Mvan_1003|M.vanbaalenii_PYR-1       VTHDSRAAQPIAEVLERRGHPYHIVGLPGSDADAA---------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           AAGGVGGFGVHPALLDAVLHAVVIAGDPD----ELALPFAWQGVSLHATG
Rv2048c|M.tuberculosis_H37Rv        AAGGVGGFGVHPALLDAVLHAVVIAGDPD----ELALPFAWQGVSLHATG
MUL_2266|M.ulcerans_Agy99           AAGSTSGFGVHPALLDAALHTAVIANPDA----DLVLPFSWQGVSLHAAG
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               DIETHG-YGIHPALLDAALHPLTAALADTNTNSGPQLPFAIAGITLHATG
Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
MAV_1763|M.avium_104                --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           ASAVRARIAPAGPSAVSVELADGLGLPVLSVASMVARPVTERQLLAAVSG
Rv2048c|M.tuberculosis_H37Rv        ASAVRARIAPAGPSAVSVELADGLGLPVLSVASMVARPVTERQLLAAVSG
MUL_2266|M.ulcerans_Agy99           AASVRVRIAPVGPSSVSVELADDLGLPVLSVKAMVARPVSEQQMRAVVSA
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               ASRMHVQLEPTATDTFRLSATDPVGAPVITIDSLTVRSLPDTDLTQPPTH
Mflv_0405|M.gilvum_PYR-GCK          ----------ELADTLRDAAADATDLRIVHVAALDAAESD----------
MAB_0939|M.abscessus_ATCC_1997      ----------ELVEALRSAADEDSALRIVHVAALAGQGS-----------
MSMEG_0408|M.smegmatis_MC2_155      ----------QLVDTLRAASAG--ELYVVHIAAGDGAAA-----------
MAV_1763|M.avium_104                ----------RLEIVLRAAAAEEAPLRIALVAALDSGTA-----------
Mvan_1003|M.vanbaalenii_PYR-1       ----------PAEEALRATVSQ-PRPHILYLAALEEPGG-----------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           SGPDRLFEVIWSPA------------------------------------
Rv2048c|M.tuberculosis_H37Rv        SGPDRLFEVIWSPA------------------------------------
MUL_2266|M.ulcerans_Agy99           SGPDRLFEVVWTPM------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               KAQQGIFELTWPALPAETFPATGVLPPWALISPHPENLSPDLNQSPTYPN
Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
MAV_1763|M.avium_104                --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           -SAATSPGPTPAYQIFESVAADQDPVAGSYVRSHQALAAVQSWLT--DHE
Rv2048c|M.tuberculosis_H37Rv        -SAATSPGPTPAYQIFESVAADQDPVAGSYVRSHQALAAVQSWLT--DHE
MUL_2266|M.ulcerans_Agy99           -TVAAT-DAAPAYELFESIAADGDPLSGTYQRTHQALAAVQSWLT--EHD
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               LTALPTCPPLVIWDLTTPQPPQSDLLHQVHTLTQHTLAGLQNWLNRSDTL
Mflv_0405|M.gilvum_PYR-GCK          -----------------------TSMKSLLRMQHRVLGGTRRLFG-----
MAB_0939|M.abscessus_ATCC_1997      -----------------------SSAQSLLRIQHQVLGGTRRLFR-----
MSMEG_0408|M.smegmatis_MC2_155      ------------------------PMRDLLRVQHRTLGGLRRLFR-----
MAV_1763|M.avium_104                -----------------------PSMRSLLRMQHRVLAGTRRLFR-----
Mvan_1003|M.vanbaalenii_PYR-1       -----------------------SAAETLGWMQHRVLAAARRLFQ-----
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           SGVLVVATRGAMALPREDVA-DLAGAAVWGLVRSAQTEHPGRIVLVDSDA
Rv2048c|M.tuberculosis_H37Rv        SGVLVVATRGAMALPREDVA-DLAGAAVWGLVRSAQTEHPGRIVLVDSDA
MUL_2266|M.ulcerans_Agy99           SGVLVVATRGAMALAGEDVT-DLAGAAVWGLVRSAQTENPGRLVLVDSDA
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               QAHLVVLTRHAVTTSPHDLAPDPAQAATAALIHTTQNEHPNRITLIDIDN
Mflv_0405|M.gilvum_PYR-GCK          ------------------------------AAVAAQLRSPMWLVTRGAQH
MAB_0939|M.abscessus_ATCC_1997      ------------------------------AAAAAELRAPIWIVTRGAQH
MSMEG_0408|M.smegmatis_MC2_155      ------------------------------AANDAELRSPIWLVTRDGQR
MAV_1763|M.avium_104                ------------------------------AAAAAELRQPIWLVTRGAQR
Mvan_1003|M.vanbaalenii_PYR-1       ------------------------------LAATAGARAPIWLITAGAQR
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           ATDDAAIAM---------ALATGEPQVVLRGGQVYTARVRGSRAADAILV
Rv2048c|M.tuberculosis_H37Rv        ATDDAAIAM---------ALATGEPQVVLRGGQVYTARVRGSRAADAILV
MUL_2266|M.ulcerans_Agy99           AVDAAAVAT---------ALAVGEPQVVLRNGQPYTARVHASRAADGILV
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               TPTTSQTLTNILTTLTNPTSAPTEPQLALRHGTPHTPRLTP----TQVLT
Mflv_0405|M.gilvum_PYR-GCK          VTDTDVVAP-----------------------------------------
MAB_0939|M.abscessus_ATCC_1997      VIEGDTVAP-----------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      VTDTDTVVP-----------------------------------------
MAV_1763|M.avium_104                VTDADTVFP-----------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       ITGDETVEP-----------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           PPGDGPWRLGLGSAGTFENLRLEPVPNADAPLGPGQVRVAMRAIAANFRD
Rv2048c|M.tuberculosis_H37Rv        PPGDGPWRLGLGSAGTFENLRLEPVPNADAPLGPGQVRVAMRAIAANFRD
MUL_2266|M.ulcerans_Agy99           PPVDGPWRLGLSSAGTFENLQLEPVPNAGAPLGPGQVRVAMRAIAANFRD
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               PPAAPNWELATTGKGDLANLALLPTP-PHTELGPGQIRVAVRAAGLNFRD
Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
MAV_1763|M.avium_104                --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           IMITLGMFTHDALLGGEGAGVVVEVGPGVTEFSVGDSVFGFFPDGSGTLV
Rv2048c|M.tuberculosis_H37Rv        IMITLGMFTHDALLGGEGAGVVVEVGPGVTEFSVGDSVFGFFPDGSGTLV
MUL_2266|M.ulcerans_Agy99           IMITLGMFTHDALIGGEGAGVVVEIGPEVTEFAVGDAVYGFFPDGSGTLV
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               VVVALGAIGEEG-LGGEAAGIIIDTGPDVTAFRRGDAVMGLFPNNAFAAT
Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
MAV_1763|M.avium_104                --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           AG-DVRLLLPMPADWSYAEAAAISAVFTTAYYAFIHLADVQPGQRVLIHA
Rv2048c|M.tuberculosis_H37Rv        AG-DVRLLLPMPADWSYAEAAAISAVFTTAYYAFIHLADVQPGQRVLIHA
MUL_2266|M.ulcerans_Agy99           AG-DVRLLLPKPADWSYAEAAAISAVFTTAYYAFVHLANVQPGQRVLVHA
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               AVTDHRMVVPIPAGWSFAAAASIPVAFLTAYGAMVELGALAAGRRVLIHA
Mflv_0405|M.gilvum_PYR-GCK          ---------DQTCLWGFGRAASLEHPQIWGGLADLGGGTSDEWSRLLNRI
MAB_0939|M.abscessus_ATCC_1997      ---------EQSALWGFGRAAALELPQVWGGLADLSDAGTDEWAQFIGRV
MSMEG_0408|M.smegmatis_MC2_155      ---------EQSCLWGFGRAAALELPHIWGGLADLSGADT-EWPRLIARI
MAV_1763|M.avium_104                ---------DQSCLWGFGRAASLEYPQLWGGLADLAQGSAEEWSRLVRVA
Mvan_1003|M.vanbaalenii_PYR-1       ---------AQTSLWGFGRAAALEQPELWGGLADVTTGDAEEWSALIDHI
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           GTGGVGMAAVQLARHLGLEVFATASKGKWDTLRAMGFDDDHISDSRSLEF
Rv2048c|M.tuberculosis_H37Rv        GTGGVGMAAVQLARHLGLEVFATASKGKWDTLRAMGFDDDHISDSRSLEF
MUL_2266|M.ulcerans_Agy99           ATGGVGMAAVQLARHLGLEVYATASKGKWDILRAMGFDEDHISDSRSLEF
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               GAGGVGQAAIQIARHFGAEVYATAHPSKHHVLKALGVSGDRIASSRTFDF
Mflv_0405|M.gilvum_PYR-GCK          AATHDPAVMEDQVAVRGSTSYVPRLVHRDTLPSGKPLHLR----------
MAB_0939|M.abscessus_ATCC_1997      SVSGEASTREDQLALRGQAVHVPRLVRREELPSGKPLEVR----------
MSMEG_0408|M.smegmatis_MC2_155      TSPRDG---EDQIALRGDAVYAPRLVRRTGEPSDTPLPVR----------
MAV_1763|M.avium_104                SAPRDPAVGEDQIALRGSDIYVPRLTRRSGQPAAAALTLR----------
Mvan_1003|M.vanbaalenii_PYR-1       VAAPTS---EDQIAVRGREIHVARLTRCAEKANAAALELR----------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           EDKFRAATGGRGFDVVLDSLAGEFVDASLRLVAPGGVFLEMGKTDIRDPG
Rv2048c|M.tuberculosis_H37Rv        EDKFRAATGGRGFDVVLDSLAGEFVDASLRLVAPGGVFLEMGKTDIRDPG
MUL_2266|M.ulcerans_Agy99           EEKFREVTGGRSVDVVLDSLAGEFVDASLRLLGPGGVFLEMGKTDIRDPG
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               VDVFNQGTNGEGMDLVLNSLAGDFVDNSLRLLSQGGRLIEIGKTDIRVPN
Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
MAV_1763|M.avium_104                --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           VIAQQYPGVRYRAFDLFEAGPDRIAQILAELATLFGDGVLRPLPVTTFDV
Rv2048c|M.tuberculosis_H37Rv        VIAQQYPGVRYRAFDLFEPGRPRMHQYMLELATLFGDGVLRPLPVTTFDV
MUL_2266|M.ulcerans_Agy99           VIAQEYPGVRYRAFDLFEPGRPRMHQYMLDLAGLFDAGVLRPLPVTAFDV
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               EVAAAHPGVIYRTYDLSSETPDRISQLWAALIEMISAGVLRPLPTTSYGL
Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
MAV_1763|M.avium_104                --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           RRAPAALRYLSQARHTGKVVMLMPG----SWAAGTVLITGGTGMAGSAVA
Rv2048c|M.tuberculosis_H37Rv        RRAPAALRYLSQARHTGKVVMLMPG----SWAAGTVLITGGTGMAGSAVA
MUL_2266|M.ulcerans_Agy99           RRAPAALRYLSQARHVGKVVMTMPADQGGALGGGTVLITGGTGMAGSALA
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               LQATQALRHMSQGRHTGKIVLLPPG---VFNSEGTVLVTGGTGMLGGVFA
Mflv_0405|M.gilvum_PYR-GCK          -------------------------------ADATYLVTGGLGSLGLEIA
MAB_0939|M.abscessus_ATCC_1997      -------------------------------SDATYLVTGGLGSIGLEIA
MSMEG_0408|M.smegmatis_MC2_155      -------------------------------EDRTYLVTGGLGAIGLEVA
MAV_1763|M.avium_104                -------------------------------ADATYLVTGGLGSIGLEIA
Mvan_1003|M.vanbaalenii_PYR-1       -------------------------------REATYLVTGGLGALGLEVA
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           RHVVARHGVRNLVLVSRRGPDAPGAAELVAELAAAGAQVQVVACDAADRA
Rv2048c|M.tuberculosis_H37Rv        RHVVARHGVRNLVLVSRRGPDAPGAAELVAELAAAGAQVQVVACDAADRA
MUL_2266|M.ulcerans_Agy99           RHLVAHHGVAHLVLISRRGPAAPGATELVAELSAAGAQVEVVACDAADRP
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               ERLVAHYGARHLLLVSRSGPDAAGADELYQRLTQLGAQVTITACDTSNPD
Mflv_0405|M.gilvum_PYR-GCK          GYLAANG-AGHLVLTSRRTPDEAAASRIEALRERHGCEVRVVTADVADAH
MAB_0939|M.abscessus_ATCC_1997      GYLAGRG-AKHLVLTSRREPGEAARQRIDALAA-QGCEVRAVTADVADGH
MSMEG_0408|M.smegmatis_MC2_155      GYLASHG-AGHVVLTSRREPGDDARRRLDGLREQYACDVRVITADVADAH
MAV_1763|M.avium_104                GHLAAQG-ARHLVLTGRRAPGEAAQRRIDALSQQHGCEVRVIAADVADAH
Mvan_1003|M.vanbaalenii_PYR-1       EFLASHG-AGHLVLTGRRSASDTVRQRIDAMRERFDCQVLVATADVADRD
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           ALAKVIADIPVQHP-LSGVIHTAGALDDAVVMSLTPDRVDVVLRSKVDAA
Rv2048c|M.tuberculosis_H37Rv        ALAKVIADIPVQHP-LSGVIHTAGALDDAVVMSLTPDRVDVVLRSKVDAA
MUL_2266|M.ulcerans_Agy99           ALAKVIAENPAQRP-LSAVVHAGGVLDDAVISSLTPERVDTVLRAKVDAA
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               ELAAVLAGIPPQHP-LRAVVHTAGIVDDAVTTELTHEQLDTVLTAKADTA
Mflv_0405|M.gilvum_PYR-GCK          AVARLLATVQAEMPPLAGIVHAAGEIGTTPLADLDDAEVDRVFAGKVWGA
MAB_0939|M.abscessus_ATCC_1997      DVARLLAGIQAELPPLAGIVHAAGEIGTTPLSDLEDAEVDRVFAGKVWGA
MSMEG_0408|M.smegmatis_MC2_155      DVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGA
MAV_1763|M.avium_104                HVARLLGAVRAELPPVAGIVHAAGEIGTTPLSDLEDAEIDRVFAGKVWGA
Mvan_1003|M.vanbaalenii_PYR-1       DVARLFSTMRSELPPLAGIVHAAGEIGTSPLRTLDDAEMDRVFAGKVWGA
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           WHLHELTRDLD--VSAFVMFSSMAGLVGSSGQANYAAANSFLDALAAHRR
Rv2048c|M.tuberculosis_H37Rv        WHLHELTRDLD--VSAFVMFSSMAGLVGSSGQANYAAANSFLDALAAHRR
MUL_2266|M.ulcerans_Agy99           WNLHELTRDLD--LSAFVMFSSMAGVVGSSGQANYAAANTFVDGLAAHRR
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               WHLHQLTTDAD--LDAFVVFSSVAGVLGAPGQANYAAANAFLDALAHQRH
Mflv_0405|M.gilvum_PYR-GCK          WHLSEATSDLQ--LDFFISTSSIASVWGGFGQAAYGAANAFLDGLAWRLR
MAB_0939|M.abscessus_ATCC_1997      WHLSEAAAGLK--LDFFINTSSIAAVWGGYGQTAYSAANAFLDGLAWRLR
MSMEG_0408|M.smegmatis_MC2_155      WHLSEALTDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLR
MAV_1763|M.avium_104                WHLSEAAADLR--LDFFVSTSSIASVWGGLGQTAYGAANAFLDGLAWRLR
Mvan_1003|M.vanbaalenii_PYR-1       VYLCEEVADMG--LDFFLATSSIASVWGSHGQTAYGAANAFLDGLADSLR
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           AHGLPAISLGWGLWDQASAMTSGLDAADLARLGREGVLALSTAEALELFD
Rv2048c|M.tuberculosis_H37Rv        AHGLPAISLGWGLWDQASAMTGGLDAADLARLGREGVLALSTAEALELFD
MUL_2266|M.ulcerans_Agy99           AHGLPAISLGWGLWDQASDMTGGMDAADRARLGREGVLALSSDEAMELFD
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               RNHLPATSLAWGYWQTTSGMTAHLDTVDQARLTRNSLTPITTEHGLAMFD
Mflv_0405|M.gilvum_PYR-GCK          EQGVAGVSVNFGPWSAG-----MADAQSRARLEQRGIKTLSPADALAGLS
MAB_0939|M.abscessus_ATCC_1997      EQGIAGTSVNFGPWSAG-----MADAESRARLEQRGIKTLSPTDALAGLA
MSMEG_0408|M.smegmatis_MC2_155      ERGVTAVSVNFGPWAAG-----MADAESRARLEQRGVRTLSPAEALAGMA
MAV_1763|M.avium_104                EQGVNGISVNFGPWAAG-----MADENARARLAQRGIKTLSPADALAGLA
Mvan_1003|M.vanbaalenii_PYR-1       ARGIPGISVNFGPWAAG-----MADAKAREQLSRRGVKTLAPADALAGMA
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           TAMIVDEP-----FLAPARIDLTALRAHAVAVPPMFSDLASAPTRRQVDD
Rv2048c|M.tuberculosis_H37Rv        TAMIVDEP-----FLAPARIDLTALRAHAVAVPPMFSDLASAPTRRQVDD
MUL_2266|M.ulcerans_Agy99           TALIVNQA-----FLAPARIDLAALRAHAVAVPPMFSDLVSAPTRRQIDA
MLBr_00135|M.leprae_Br4923          -----------------------------------------------MTA
MMAR_3798|M.marinum_M               VALACQHP-----CLVPAPLNTQVLAGYARQN-----ALPAILSAVTTTR
Mflv_0405|M.gilvum_PYR-GCK          DAVISAAP---HPVVARVDWSRFLPLYQQAGRRGFLAELERELPAAPAQQ
MAB_0939|M.abscessus_ATCC_1997      DVVAASGSNAVQGVIARIDWARFLPLYQQAGKRGFLAELDREVPSHLA--
MSMEG_0408|M.smegmatis_MC2_155      DVVAGPVQ----GVVAKIDWSRFLPLYQQAGRRAFLSELESELPAAATGA
MAV_1763|M.avium_104                DVMATAAA---QGVVARIDWTRFLPLYQQAGQRSLLAELAREIPDFAP--
Mvan_1003|M.vanbaalenii_PYR-1       DVIAASTA---HAVVARIDWATFLPVYQLQRRRAFLSQLEREVPDVPD--
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           SVAAAKSKSALAHRLHGLPEAEQHAVLLGLVRLHIATVLGNITPEAIDPD
Rv2048c|M.tuberculosis_H37Rv        SVAAAKSKSALAHRLHGLPEAEQHAVLLGLVRLHIATVLGNITPEAIDPD
MUL_2266|M.ulcerans_Agy99           ALATAKSKSALAHRLHGLPELEQHAVVLDLVRSHIATVLGTITPEAIDPD
MLBr_00135|M.leprae_Br4923          SVEGADQK------------------------------------------
MMAR_3798|M.marinum_M               RQATTTNTETFTSRLASQTPQQQLAILSDLVTDMTAAVLAHPDSAALDAD
Mflv_0405|M.gilvum_PYR-GCK          GPAVTASGRTPLVERLTTAPLQQRKRLLTDYLRDAVAEVTRVDAAEIRED
MAB_0939|M.abscessus_ATCC_1997      GVAGAQSGSTQLVERLANAPVQQRKKLLTDYLRDAVAEVTRVDVSEIRED
MSMEG_0408|M.smegmatis_MC2_155      AAPATVPGKPPLVEQLTKAPVQQRKSLITNYLRNAVAEVTRVDADEIRDE
MAV_1763|M.avium_104                --APTPSGKTGLVERLAGAPVQQRRKLMTEFLRNAVAEVTRVDAAEIRED
Mvan_1003|M.vanbaalenii_PYR-1       ASAPAPSGTTRFVEELTLAPVEQRRKLVLEYLRAAVAEVTRVDAAEIRDE
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           KAFQDLGFDSLTAVEMRNRLKSATGLSLSPTLIFDYPTPNRLASYIRTEL
Rv2048c|M.tuberculosis_H37Rv        KAFQDLGFDSLTAVEMRNRLKSATGLSLSPTLIFDYPTPNRLASYIRTEL
MUL_2266|M.ulcerans_Agy99           KAFQELGFDSLTAVEMRNRIKTVTGLSLSPTLIFDYPTPNGLANYIRAEL
MLBr_00135|M.leprae_Br4923          --------------------------------------SEKLISYLKKVV
MMAR_3798|M.marinum_M               LPFKDLGIDSLSALELRNSLARHTGLTLSATLVFDHPTPTAIAHHLVDQL
Mflv_0405|M.gilvum_PYR-GCK          AGFFDLGMDSLMAVELRRRIETGVGKEIPVTLVMDHPRLSDAADYLLGDV
MAB_0939|M.abscessus_ATCC_1997      AGFFDLGMDSLMAVELRRRMEQGVGKEIPVTLVMDHPRISDVADYLLGDV
MSMEG_0408|M.smegmatis_MC2_155      AGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEV
MAV_1763|M.avium_104                AGFFDLGMDSLMAIELRRHIEQGVGKQIPATLAMDYPRLSDVAEYLLGDV
Mvan_1003|M.vanbaalenii_PYR-1       AGFFDLGMDSLMAIELRRRLEQGLGKELPVTLAMDHPHLSDAAEYVLGDV
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           AGLPQEIKHTPAVRT-------TSEDPIAIVGMACRYPGGVNSPDDMWDM
Rv2048c|M.tuberculosis_H37Rv        AGLPQEIKHTPAVRT-------TSEDPIAIVGMACRYPGGVNSPDDMWDM
MUL_2266|M.ulcerans_Agy99           AGAPQEVKHTPAVRV-------TGDDPIAIVGMSCRYPGGIESPDDLWDM
MLBr_00135|M.leprae_Br4923          VELDETRARLREYEQ-------RATEPVAVVGIGCRFPGGVDSPDRLWDV
MMAR_3798|M.marinum_M               SAAAPPAPVATPVKA-------NAEEPVVVVGMACRLPGGIESAAGLWDV
Mflv_0405|M.gilvum_PYR-GCK          LGLTEAAT-APKAAT---VVSTAADEPIAIVAVSCRFPG-APNPEAFWDL
MAB_0939|M.abscessus_ATCC_1997      LGLAEQAKPAAQLAS---AVTGRTDEPIAIVAVSCRFPG-APDPEAFWDV
MSMEG_0408|M.smegmatis_MC2_155      LGLGEQTN--VRQAS---TVTARTDDPIAVVAVSCRFPG-APDPESFWEL
MAV_1763|M.avium_104                LDLRGQPDAKPAPPAGTPAPAGRTDEPIAIVAMACRFPG-AADPEAFWEL
Mvan_1003|M.vanbaalenii_PYR-1       LGLSEHTVAQPDTPS-----TVRTDDPIAIVGMACRFPG-ADDTDAFWSV
TH_4621|M.thermoresistible__bu      ----------VNIVG------DTPVNAVAVIGMACRLPGGIDSPQRLWEA
                                                             :.:.::.:.** **   ..  :*. 

Mb2074c|M.bovis_AF2122/97           LIQGRDVLSEFPADRGWDLAGLYNPDPDAAGACYTRTGGFVDGVGDFDPA
Rv2048c|M.tuberculosis_H37Rv        LIQGRDVLSEFPADRGWDLAGLYNPDPDAAGACYTRTGGFVDGVGDFDPA
MUL_2266|M.ulcerans_Agy99           LMARRDVLSDFPADRGWDLAGLFNPDPDVPGACYTRTGGFVDRVGDFEPA
MLBr_00135|M.leprae_Br4923          VSECRDVVSEFPTDRGWDVDGLFDPDPDAEGKTYTRWGAFLDDAAGFDAG
MMAR_3798|M.marinum_M               VSGAADVMGAFPTDRGWDVAGLFDPDPDSVGKTYTRYGGFISSAAEFDAE
Mflv_0405|M.gilvum_PYR-GCK          LSGGVDAIREVPEDR-FDIDEFYDPDPDAAGKTYTRYGGFLDHIDEFDPE
MAB_0939|M.abscessus_ATCC_1997      LSGGVDAIREVPEDR-FDIDEFYDPDPEVAGKTYTRFGGFLDGIDGFDPE
MSMEG_0408|M.smegmatis_MC2_155      LAGGVDAIREVPEDR-WDIDEFYDPDPDTPGKTYTRFGGFLDGIDGFDPE
MAV_1763|M.avium_104                LSGGVDAIREVPEDR-FDIDEFYDPDPETPGKMYSRFGGYLDQIDEFDPE
Mvan_1003|M.vanbaalenii_PYR-1       LAEGADLIREIPDDR-FDINEFYDPDPEAAGKIYSRYGGFLDGVDGFDPE
TH_4621|M.thermoresistible__bu      LLRGDDMVTEIPVDR-WDADDYFDPEPGVPGRTVSRWGAFLDDVAGFDPE
                                    :    * :  .* ** :*    ::*:*   *   :* *.::.    *:. 

Mb2074c|M.bovis_AF2122/97           FFGVGPSEALAMDPQQRMLLELSWEALERAGIDPTGLRGSATGVFAGVMT
Rv2048c|M.tuberculosis_H37Rv        FFGVGPSEALAMDPQHRMLLELSWEALERAGIDPTGLRGSATGVFAGVMT
MUL_2266|M.ulcerans_Agy99           FFGVGPSEALAMDPQQRMFLELSWEALERAGIEPGGLRGSATGVFAGVMT
MLBr_00135|M.leprae_Br4923          FFGIAPSEVLAMDPQQRLMLEVSWEALEYAGIDPLSLRGSATGVFTGIFA
MMAR_3798|M.marinum_M               FFGISAREAAAMDPQQRVLLEVCWEALEHAGIEPGTLEGSNTGVFIGAYA
Mflv_0405|M.gilvum_PYR-GCK          FFGLSPREAVWIEPQQRLMLETVWEGLERAGYAPSALRGSRTGVFVGVAA
MAB_0939|M.abscessus_ATCC_1997      FFGISPREAVWIEPQQRLMLETVWEGLERAGYSPAALRGSRTGIFAGVGA
MSMEG_0408|M.smegmatis_MC2_155      FFGISPREAVWIEPQQRLMLETVWEGLERAGYAPSDLRGSRTGVFTGVAA
MAV_1763|M.avium_104                FFGISPREAVWIDPQQRLVLETVWEGLERAGYSPAALRGSRSGIFVGVGA
Mvan_1003|M.vanbaalenii_PYR-1       FFGISPREAVWIDPQQRLVLETAWEGLERAGYSAAALRGSRSGVYVGVGA
TH_4621|M.thermoresistible__bu      FFGISEREAISIDPQQRLLLETSWEAMEHAGLTPADVEGSSTGVFVGLSH
                                    ***:.  *.  ::**:*:.**  **.:* **  .  :.** :*:: *   

Mb2074c|M.bovis_AF2122/97           QGYGMFAA----EPVEGFRLTGQLSSVASGRVAYVLGLEGPAVSVDTACS
Rv2048c|M.tuberculosis_H37Rv        QGYGMFAA----EPVEGFRLTGQLSSVASGRVAYVLGLEGPAVSVDTACS
MUL_2266|M.ulcerans_Agy99           QGYGMFAA----EPVEGFRLTGQLSSVASGRVAYVLGLEGPAVSVDTACS
MLBr_00135|M.leprae_Br4923          PSYGSRDT----GGLQGYGLTGTAVSVASGRVSYVLGLEGPAVSVDTACS
MMAR_3798|M.marinum_M               QRYGDSDS----DSGEGFALTGGATSVASGRVAYVLGLQGPAITVDTACS
Mflv_0405|M.gilvum_PYR-GCK          NEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGLEGPAVAVDTACS
MAB_0939|M.abscessus_ATCC_1997      NEYAHLLSSESIDKIEPYFITGNALNAISGRVAFALGFEGPAVAVDTACS
MSMEG_0408|M.smegmatis_MC2_155      NEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGFEGPAVAVDTACS
MAV_1763|M.avium_104                NEYSHLLSAESVDKIEPHFITGNALNAISGRVAFALGLEGPAVAVDTACS
Mvan_1003|M.vanbaalenii_PYR-1       NEYSHLLSGGSLDGIEAQFITGNALNVIAGRVSFTLGLEGPAVAVDTACS
TH_4621|M.thermoresistible__bu      DDYALLTSDAG-ALEEAYGFTGSAFSMASGRIAYRLGVHGPAVTVDTACS
                                      *.   :       :   :**   .  :**::: **..***::******

Mb2074c|M.bovis_AF2122/97           SSLVALHMAVGSLRSGECDLALAGGVTVNATPDIFVEFSRWRGLSPDGRC
Rv2048c|M.tuberculosis_H37Rv        SSLVALHMAVGSLRSGECDLALAGGVTVNATPDIFVEFSRWRGLSPDGRC
MUL_2266|M.ulcerans_Agy99           SSLVALHMAVQSLRSGECDLALAGGVTINATPDIFVEFSRWRGLSADGRC
MLBr_00135|M.leprae_Br4923          SSLVAIHWAMSSLRSGECDLALAGGVTVMGLPSIFVGFSRQRGLAADGRC
MMAR_3798|M.marinum_M               SSLVAAHLACQSLRNGESSLALAGGVTIMATPAPFIEFARQRGLAADGRC
Mflv_0405|M.gilvum_PYR-GCK          SSLVAVHQATQALRSGDCDMALAGGVNVLLSPVTVVAASRARMLSPVGRC
MAB_0939|M.abscessus_ATCC_1997      SALVAVHQAVQALHSGDCDLALAGGVNVLLSPVTVIAASRARMLSPVGRC
MSMEG_0408|M.smegmatis_MC2_155      SALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRC
MAV_1763|M.avium_104                SSLVAVHQACQALHSGDCDLALAGGVNVLLSPVSNIAASRARMLSPVGRC
Mvan_1003|M.vanbaalenii_PYR-1       SSLVAVHQACQGLQSGDCDLALAGGVNVLLSPATTIATSRARMLSPDGRC
TH_4621|M.thermoresistible__bu      SSLLAVHMACRSLQVGESDLALAGGAMVMLEPRKYTSASGLGMLSPTGRC
                                    *:*:* * *  .*: *:..:*****. :   *      :    *:. ***

Mb2074c|M.bovis_AF2122/97           KAFAAAADGTGFSEGGGMLVLQRLSDARRLGHPVLAVVVGSAVNQDGASN
Rv2048c|M.tuberculosis_H37Rv        KAFAAAADGTGFSEGGGMLVLQRLSDARRLGHPVLAVVVGSAVNQDGASN
MUL_2266|M.ulcerans_Agy99           KAFAGAADGTGFSEGGGMLVVERLSDAQRLGHPVLALVRGSAVNQDGASN
MLBr_00135|M.leprae_Br4923          KAFARAADGTGWGEGAGVVVLERLSDAQRLGHTVLAVVRGSAVNQDGASN
MMAR_3798|M.marinum_M               KAFAAAADGTGWGEGAAVLVLERLSDARRNRHPVLAVIAGSAVNQDGASN
Mflv_0405|M.gilvum_PYR-GCK          KTFDASADGYVRSEGCGILVLKRLSDAVRDGDRVCAVIAGSAVNQDGASS
MAB_0939|M.abscessus_ATCC_1997      KTFDASADGYVRSEGCGILVLKRLSDAERDGDRVLAVIPGSAVNQDGASS
MSMEG_0408|M.smegmatis_MC2_155      KTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASS
MAV_1763|M.avium_104                KTFDATADGYVRSEGCGILVLKRMSDAVRDGDRVCAVIPASAVNQDGASS
Mvan_1003|M.vanbaalenii_PYR-1       KTFDAAADGYVRGEGCGILVLKRLSDAVRDGDRIQAVIRGSAVNQDGASG
TH_4621|M.thermoresistible__bu      HAFDVAADGFVRSEGSVMLLLKRLPDALRDNDRILAVVRGTAANQDGRTE
                                    ::*  :***   .**  :::::*:.** *  . : *:: .::.**** : 

Mb2074c|M.bovis_AF2122/97           GLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTTLGDPIEAQALL
Rv2048c|M.tuberculosis_H37Rv        GLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTTLGDPIEAQALL
MUL_2266|M.ulcerans_Agy99           GLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTTLGDPIEAQALL
MLBr_00135|M.leprae_Br4923          GLTAPNGLAQQRVIQAALTNAGLSSADVDVVEAHGTATTLGDPIEAQALL
MMAR_3798|M.marinum_M               GLSAPNGPAQQRVIAQAAANAGIALDQVDVVEAHGTGTTLGDPIEAGALI
Mflv_0405|M.gilvum_PYR-GCK          GLTVPNGGAQQRLIGTVLARAGITGGEVDYLEAHGTGTPLGDPIEVQAAA
MAB_0939|M.abscessus_ATCC_1997      GLTVPNGGAQQRLIGSVLARAGLVGGDVDYLEAHGTGTPLGDPIEVQAAA
MSMEG_0408|M.smegmatis_MC2_155      GLTVPNGGAQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQAAA
MAV_1763|M.avium_104                GLTVPNGGAQQRLIATALSRAGLSGDDVDYLEAHGTGTALGDPIEVQAAG
Mvan_1003|M.vanbaalenii_PYR-1       GLTVPNGGAQQRVIAAALTRAGLSGSDIDYLEAHGTGTSLGDPIEVQAAG
TH_4621|M.thermoresistible__bu      NISTPSIQAQADVYRSALAVAGVDPATVGMVEAHGTGTPVGDPIEYNSLT
                                    .::.*.  :*  :   . : **:    :. :*.***.*.:*****  :  

Mb2074c|M.bovis_AF2122/97           ATYGQDRGEP---GEPLWLGSVKSNMGHTQAAAGVAGVIKMVLAMRHELL
Rv2048c|M.tuberculosis_H37Rv        ATYGQDRGEP---GEPLWLGSVKSNMGHTQAAAGVAGVIKMVLAMRHELL
MUL_2266|M.ulcerans_Agy99           ATYGQDRGSAGAAGKALWLGSIKSNMGHTQAAAGVAGVIKMVQAMRHEVL
MLBr_00135|M.leprae_Br4923          ATYGQGRPAD----QPLWVGSIKSNMGHTQAAAGVAGVIKMVQAMRHHVM
MMAR_3798|M.marinum_M               ATYGTHRDPE----HPLWLGSVKSNIGHTQAAAGAAGLIKMIQAMRHGVL
Mflv_0405|M.gilvum_PYR-GCK          AAYAGARDAD----RPLLMGSVKTNIGHTESASGAAGLIKVVLSLQHETL
MAB_0939|M.abscessus_ATCC_1997      AAYGGSRDAD----RPLLMGSVKSNIGHTESASGAAGLIKVVLSLQNGVL
MSMEG_0408|M.smegmatis_MC2_155      AAYGAGRDAD----RPLLMGSVKTNIGHTESASGAAGLIKVVLSLQHGVL
MAV_1763|M.avium_104                AVYGATRDTD----RPLLIGSVKTNIGHLEAASGVAGLIKVVLSLQHEML
Mvan_1003|M.vanbaalenii_PYR-1       AVLGAGRDPD----RPLLMGSVKTNVGHLESASGVAGLIKVVLSLQHEML
TH_4621|M.thermoresistible__bu      QVYGKT--------GPCALTSVKTNFGHAESAAGALGMMKAILALQHGVV
                                     . .           .  : *:*:*.** ::*:*. *::* : ::::  :

Mb2074c|M.bovis_AF2122/97           PATLHVDVPSPHVDWSAGAVELLTAPRVWP---AGARTRRAGVSSFGISG
Rv2048c|M.tuberculosis_H37Rv        PATLHVDVPSPHVDWSAGAVELLTAPRVWP---AGARTRRAGVSSFGISG
MUL_2266|M.ulcerans_Agy99           PATLHVDVPSPHVDWSAGAVELLTEAQPWPAESAGDRVRRAGVSSFGISG
MLBr_00135|M.leprae_Br4923          PATLHVDEPSPRVDWTTGAVSVLTEARDWS---VEGRPRRAGVSSFGISG
MMAR_3798|M.marinum_M               PKTLHVNAPTPQVDWSAGTVRLLTETMPWP---DTDHLRTAAVSSFGVSG
Mflv_0405|M.gilvum_PYR-GCK          PQSLHFDTPSPHIPWDSLPVRVVDTAMPWQ---PNGRPRRAGVSSFGFTG
MAB_0939|M.abscessus_ATCC_1997      PQSLHFDNPSPHIPWESLPVRVVDKAIPWQ---ANGRPRRAGVSSFGFTG
MSMEG_0408|M.smegmatis_MC2_155      PQSLHFENPSPHIPWDALPVRVIDEPVPWQ---TNGRVRRAGVSSFGFTG
MAV_1763|M.avium_104                PQSLHFETPSPHIPWDSLPLRVVDKAVPWQ---TNGRPRRAGVSSFGFTG
Mvan_1003|M.vanbaalenii_PYR-1       PRHLHFKTPSPHIPWDRLAVRVVAEPTPWR---ADGRPRRAGVSSFGFSG
TH_4621|M.thermoresistible__bu      PQNLHFTRLPDEMAAIETNLFVPQATTLWP--VREGCPRRAAVSSYGMSG
                                    *  **.   . .:      : :   .  *         * *.***:*.:*

Mb2074c|M.bovis_AF2122/97           TNAHVIIEAVP---------------VVPRR-EAGWAGPVVPWVVSAKSE
Rv2048c|M.tuberculosis_H37Rv        TNAHVIIEAVP---------------VVPRR-EAGWAGPVVPWVVSAKSE
MUL_2266|M.ulcerans_Agy99           TNAHVIVEAAP---------------RVEVGGSSGGAVPVVPWVVSAKSG
MLBr_00135|M.leprae_Br4923          TNAHVILEEAPT------------PVEASYSTADQQRLSVVPWVVSGRST
MMAR_3798|M.marinum_M               TNAHLIVQQGSPG-----------PAVAVHQASPSQECSLGVWPLSARSS
Mflv_0405|M.gilvum_PYR-GCK          TNAHVLIEEAPTDLAGPTEPTAPAEPVDEDAAADPAPAPVEVLPLSARSP
MAB_0939|M.abscessus_ATCC_1997      TNAHVLIEEAPQPQATP----------DEDDASTPQSAPVSVLPLSARSP
MSMEG_0408|M.smegmatis_MC2_155      TNAHVLVEEAPPQLHTADAAP----VEPAATAEAGTDDSPQVLALSARSP
MAV_1763|M.avium_104                TNAHVLIEEAPQPVTTQ----------DATPAAESDARPVDVLPLSARSP
Mvan_1003|M.vanbaalenii_PYR-1       TNAHVVLEEPPAQSADLRQPPTDGKDGAAGLESATAPEPAGVLPISARSP
TH_4621|M.thermoresistible__bu      TNVHAVLEQAPEP------------VQRPEESADTDAAGPLVFALSSTSA
                                    **.* :::  .                                 :*. * 

Mb2074c|M.bovis_AF2122/97           SALRGQAARLAAYVRGD-DGLDVADVGWSLAG-RSVFEHRAVVVGG----
Rv2048c|M.tuberculosis_H37Rv        SALRGQAARLAAYVRGD-DGLDVADVGWSLAG-RSVFEHRAVVVGG----
MUL_2266|M.ulcerans_Agy99           SALGAQAARLAAHVRSH-DELDVADVGWSLAG-RSTFEHRAVVLGA----
MLBr_00135|M.leprae_Br4923          AALMAQASRLAFYVQAD-PEVDPVDVGCALAA-RSVFEHRAVVVGE----
MMAR_3798|M.marinum_M               AGLSAQAHRLHEYLLGH-SDLDLIDLAYSLATTRTHHSYRAAVTVPGCTD
Mflv_0405|M.gilvum_PYR-GCK          EALVALAQRYETWLTAH-PEADLADVCRTAGTGRSHFEHRAALVVD----
MAB_0939|M.abscessus_ATCC_1997      EALAAVAQRYESWLAAH-PDVDLEDVCLTAGRGRSHFEHRAALVVD----
MSMEG_0408|M.smegmatis_MC2_155      EALVELARRYDDWLSAT-PGLDIADVCHTAGVGRSHFEYRAALVVD----
MAV_1763|M.avium_104                EALLALAQRYGEWLHAH-PDADIGDLCFTVGAGRAHFEHRAALVVD----
Mvan_1003|M.vanbaalenii_PYR-1       EALTALARRYESWLTAH-PDADIADVCYTAGAGRSHFEHRAALVVD----
TH_4621|M.thermoresistible__bu      EELRRTAGRLAEWVEAHTDEVVPADLAYTLARRRAHRPVRTTVIADG---
                                      *   * *    : .        *:  : .  *:    *:.:       

Mb2074c|M.bovis_AF2122/97           -DRDRLLAGLDELAGDQLG--GSVVRGTATAAGKTVFVFPGQGSQWLGMG
Rv2048c|M.tuberculosis_H37Rv        -DRDRLLAGLDELAGDQLG--GSVVRGTATAAGKTVFVFPGQGSQWLGMG
MUL_2266|M.ulcerans_Agy99           -DRDGLLAGLDELAGDEFGG-ASVIRGVAGAAGKTVFVFPGQGSQLLGMG
MLBr_00135|M.leprae_Br4923          -SREQLIAGLAGLAVGESG--AGVAIGQAAPLGKTVVVFPGQGAQRIGMG
MMAR_3798|M.marinum_M               NAHHDLLGGLTALAAGQTHPFVANHYCRAGQNGKTVFVFPGQGGQYPAMA
Mflv_0405|M.gilvum_PYR-GCK          -SVESARIALTDLAQNRLR--PGVVRGEHLNHPTTAWMFTGQGSQYPGMA
MAB_0939|M.abscessus_ATCC_1997      -SIQTAREGLLELAQNRLR--PGVVRGEHTNHPTTAWLFTGQGSQYPGMA
MSMEG_0408|M.smegmatis_MC2_155      -SVERAREGLAALAEGRTP--AGVVRGEHVHRPTTAWLFTGQGSQYPGMA
MAV_1763|M.avium_104                -SVRSAREALADLADNRTR--PGVARGECTDPPTTAWLFTGQGSQYPGMA
Mvan_1003|M.vanbaalenii_PYR-1       -SVDGARDLLAGLAEDRLG--PGAVRGVCGDPPKTAWLFTGQGSQYPGMA
TH_4621|M.thermoresistible__bu      --VEALTAGLREVADGDAP----YQPAVGMDDKAPVWVFSGQGSQWAGMG
                                             *  :* .                  .. :*.***.*  .*.

Mb2074c|M.bovis_AF2122/97           MGLHAGYPVFAEAFNTVVGELDRHLLRPLREVMWG-------HDENLLNS
Rv2048c|M.tuberculosis_H37Rv        MGLHAGYPVFAEAFNTVVGELDRHLLRPLREVMWG-------HDENLLNS
MUL_2266|M.ulcerans_Agy99           MGLHAGYPVFAEAFNTVVGELDRHLLRPLREVIWG-------HDENLLNT
MLBr_00135|M.leprae_Br4923          RELCSQLPVFAEEFDAVTGELDRHMRLPLRDVVWG-------ADAGLLDS
MMAR_3798|M.marinum_M               AELYRQHPGFATAVDECDAELRPYTGWSVRDVICQD------PDAPSLEL
Mflv_0405|M.gilvum_PYR-GCK          RELFDTEPVFADTVTRCADAVADLLPRPLLDVMFAGGREAGVPPTETLRH
MAB_0939|M.abscessus_ATCC_1997      RELFDAEPVFAETVTRCAEAVKDIVTRPLLEVMFATDRETGGKAGEALRH
MSMEG_0408|M.smegmatis_MC2_155      RELFDTQPVFAQTVRQCAEAVADMLPRPLLDVLFATDRET----ADLLQH
MAV_1763|M.avium_104                RELFDAEPVFAETVTRCADAVDGLLPRPLTEVIFATDKDTGGEAGKTLRN
Mvan_1003|M.vanbaalenii_PYR-1       RELFDTEPVFRDTVTRCAEAIGDTLPRPLLEVLFDTDGDN----GQTLRH
TH_4621|M.thermoresistible__bu      AELLATEQVFAAKIAEIEPLVARESGFSVTEAMTAS---------ETVTG
                                      *      *   .      :      .: :.:              :  

Mb2074c|M.bovis_AF2122/97           TEFAQPALFAVEVALFRLLGSWGVRPDFVMGHSIGELSAAHVAGVLSLEN
Rv2048c|M.tuberculosis_H37Rv        TEFAQPALFAVEVALFRLLGSWGVRPDFVMGHSIGELSAAHVAGVLSLEN
MUL_2266|M.ulcerans_Agy99           TEFAQPALFAVEVALYRLLESWGVRPDFVMGHSVGELSAAHVAGVLSLEN
MLBr_00135|M.leprae_Br4923          TEFAQPALFAVEVALFAVLQHWGLQPDFVMGHSIGELAAAYVAGVLAPAD
MMAR_3798|M.marinum_M               VEVIQPVLFAVMIALAETLRGYGIVPDAVIGHSQGEIAAAYIAGALTLAE
Mflv_0405|M.gilvum_PYR-GCK          TSFAQPALFAVEMGLARLWQSWGIVPDVVLGHSVGQYAAACVAGVFSLED
MAB_0939|M.abscessus_ATCC_1997      TSFAQPALFAVEMGLARLWQSWGIEPDVVLGHSVGQYAAACVAGVFSIED
MSMEG_0408|M.smegmatis_MC2_155      TSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACVAGVFSLDD
MAV_1763|M.avium_104                TAFAQPALFAVEMGLARLWQSWGVEPDVVLGHSVGQYAAACVAGVFSLED
Mvan_1003|M.vanbaalenii_PYR-1       TSYAQPALFAIEMGLARLWQARGIEPDVVLGHSVGQYAAACVAGVFGLED
TH_4621|M.thermoresistible__bu      IDRVQPTLFAIQVALAATMQSYGVRPGAVIGHSLGEVAAAVVAGALSLED
                                        **.***: :.*       .: *. *:*** *: :** :**.:   :

Mb2074c|M.bovis_AF2122/97           AAVLVAARGRLMQALPAGGAMVAVQAAEEEVRPLLS----AEVDIAAVNG
Rv2048c|M.tuberculosis_H37Rv        AAVLVAARGRLMQALPAGGAMVAVQAAEEEVRPLLS----AEVDIAAVNG
MUL_2266|M.ulcerans_Agy99           AAVLVAARGRLMQALPDGGAMIAVQATEQEVLPLLG----AQVSIATING
MLBr_00135|M.leprae_Br4923          AAMLVVARGRLMQSMPAGGTMWAVAASEDEVVSLLG----EGVGIAAINA
MMAR_3798|M.marinum_M               AAKVVALRSAALAQLAGTGTMASVLLSPEELRPLLQP-WNTQISIAAING
Mflv_0405|M.gilvum_PYR-GCK          GARLMAERGRLFGSLPEGGRMVAVFADAKRVEQVAA--DFPRVSVGAYNG
MAB_0939|M.abscessus_ATCC_1997      GARLIAERGRLFGGLPAGGRMVAVFSDAKHVEQIAG--EFPRVSVGAYNG
MSMEG_0408|M.smegmatis_MC2_155      GARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAG--EFPRVSVGAYNG
MAV_1763|M.avium_104                GARLMAERGRLFGGLPDGGRMVAVFADAQYVEELAN--DCPRVSVAAYNG
Mvan_1003|M.vanbaalenii_PYR-1       GARLVADRGRLFGGLPVGGRMVAVFTDAEVVEDFAD--EFPQVSVAAYNG
TH_4621|M.thermoresistible__bu      GVKVICRRSRLCLRLAGAGAMAAIELPAQAVREFLAARGVDDVVLSVIAS
                                    .. ::  *.     :.  * * ::    . :  .        : :..  .

Mb2074c|M.bovis_AF2122/97           PASLVISGAQNAVAAVADQLRADGRRVHQLAVSHAFHSPLMDPMIDEFAA
Rv2048c|M.tuberculosis_H37Rv        PASLVISGAQNAVAAVADQLRADGRRVHQLAVSHAFHSPLMDPMIDEFAA
MUL_2266|M.ulcerans_Agy99           PASVVISGAQDAVSAVAEQLRADGRRVHRLAVSHAFHSPLMDPMIDEFAT
MLBr_00135|M.leprae_Br4923          PESVVISGPQAAVSAIADKFAAQGRRVHQLAVSHAFHSPLMEPMLEEFVR
MMAR_3798|M.marinum_M               PAHTIISGDTTAVEQFIGTCEDGGVQIRPIAVDYASHSAHVERLREHLLH
Mflv_0405|M.gilvum_PYR-GCK          PN-TVLSGPGEDLEQIVGTFGEDGIRCTWLETSHAFHSELLDPVLDEFES
MAB_0939|M.abscessus_ATCC_1997      PN-TVLSGPGEDLEQAVARFQEEGIRCTWLETSHAFHSELLDPILDEFES
MSMEG_0408|M.smegmatis_MC2_155      PN-TVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDEFEA
MAV_1763|M.avium_104                PN-TVLSGPGADLEQIVARGASDGIRCSWLETSHAFHSELLDPVLDEFES
Mvan_1003|M.vanbaalenii_PYR-1       PN-TVLAGPASDLEQIVAGCSGEGIRTTWLDTSHAFHSALLDPVLDEFES
TH_4621|M.thermoresistible__bu      PESTVIGGATDTVRELVAAWEAQGVMAREVAVDVASHSPQVDPILDELEE
                                    *   ::.*    :          *     : .. * **  :: : :.:  

Mb2074c|M.bovis_AF2122/97           VAAGIAIGRPTIGVISNVTGQLAGDDFGS----AAYWRRHIRQAVRFADS
Rv2048c|M.tuberculosis_H37Rv        VAAGIAIGRPTIGVISNVTGQLAGDDFGS----AAYWRRHIRQAVRFADS
MUL_2266|M.ulcerans_Agy99           VAGELTVNAPTIGIISNLTGQLAGEDFGS----AAYWKRHVRDAVRFADS
MLBr_00135|M.leprae_Br4923          VAAQVEVRKPQIGLVSNVTGELAGPDFGS----PQYWGEHVSRAVRFVDS
MMAR_3798|M.marinum_M               ELADLNPQPARIPLYSTVASELSEHPLDTTAMDAEYWYRNLREPVEFYSC
Mflv_0405|M.gilvum_PYR-GCK          YAAQLQFAAPTLPLVCNRTGAVLTGQTSLD---AQYWRRHSRQPVQFAES
MAB_0939|M.abscessus_ATCC_1997      YAAQVQFAAPTLPLVCNRTGAVLTAQTPID---GQYWRRHSRQPVQFAES
MSMEG_0408|M.smegmatis_MC2_155      YAAQFQFAAPTLPLVCNRTGAVLTGQTPLD---AQYWRRHSRQPVQFAES
MAV_1763|M.avium_104                YAAHLDFAVPTLPLVCNRTGTVLTTETPLD---ARYWRRHSRQPVQFAES
Mvan_1003|M.vanbaalenii_PYR-1       CAARLAYAAPTRPLVCNRTGAVVTGPGVID---AQYWRRHARQPVQFAES
TH_4621|M.thermoresistible__bu      ILADLQPMTPTVPYYSATSYDPREKPVCD----ADYWVDNLRHEVRFAAA
                                      . .    .     .  :                **  :    *.*  .

Mb2074c|M.bovis_AF2122/97           VRFAQAAGGSRFLEVGPSGGLVASIEESLPDVAVT----TMSALRKDRPE
Rv2048c|M.tuberculosis_H37Rv        VRFAQAAGGSRFLEVGPSGGLVASIEESLPDVAVT----TMSALRKDRPE
MUL_2266|M.ulcerans_Agy99           IRFAQSAGAARFLEVGPSIGLTASIEEVLSDAAVTNPVATASALRKDRPE
MLBr_00135|M.leprae_Br4923          ARHLQTLGATHFIESGPSSGLMGAIEQSLAPAEAV----VVSMMGKDRPE
MMAR_3798|M.marinum_M               VAQLLAHSERVFVELSPHPVLASALTDALADTGQLTQSAVVTTLRRDRPD
Mflv_0405|M.gilvum_PYR-GCK          VRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHLAAPR--AIASLRKGVAD
MAB_0939|M.abscessus_ATCC_1997      VRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHLAPPR--AIVSLRKGVED
MSMEG_0408|M.smegmatis_MC2_155      VRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHMAAPR--AVASLRKGVAD
MAV_1763|M.avium_104                VRTVAALGCTVLMEIGPQPVLTGAAVQVWPEHLAAPR--AIVSLRKGVGD
Mvan_1003|M.vanbaalenii_PYR-1       VRTLADLGCSVLMEIGPQPFLIAAALRVWPESAATPR--AIPSLRKGPDA
TH_4621|M.thermoresistible__bu      VQAALEDGFRVFGELSPHPLLTRAVEQTARGLDMPVA--ALPAMRREQEM
                                           .   : * .*   *  :               .   : :    

Mb2074c|M.bovis_AF2122/97           PATLTNAVAQGFVTGMDLDWRAVVG--EAQFVELPTYAFQRRRFWLS-GD
Rv2048c|M.tuberculosis_H37Rv        PATLTNAVAQGFVTGMDLDWRAVVG--EAQFVELPTYAFQRRRFWLS-GD
MUL_2266|M.ulcerans_Agy99           PVSLVSALAGVFVAGTAVDWRAVVG--QSHFVELPTYAFERRRFWLS-GD
MLBr_00135|M.leprae_Br4923          LASVLGAAGQLFATGMPVEWPAVFAGSSRRRVTLPTYAFQRRRFWETPGT
MMAR_3798|M.marinum_M               MDMVASAIANLHVHGHSPSWQKIYP--GATTVELPTYAFQRRHYWLAAPT
Mflv_0405|M.gilvum_PYR-GCK          RRQIADALAAAYIGGHKPDFAALHEQ-RGVRLELPTYPFQRRRFWPKSAG
MAB_0939|M.abscessus_ATCC_1997      RRQIADALASAYVSGHRPNFAALQRH-PRRTVELPTYPFQRRRFWPKSSG
MSMEG_0408|M.smegmatis_MC2_155      RRQIADALASAYVGGHRPDFAAVHRQ-PRRPVELPTYPFQRRRFWPKASS
MAV_1763|M.avium_104                RRQIAEGLAAAYVSGHRPEFAALHRR-PRRKLELPTYPFQRRRFWPKASG
Mvan_1003|M.vanbaalenii_PYR-1       RRQLAEAVAAAYIAGHRLDFTGHDGG-PHRRLPLPTYPFQHRSYWPKTAG
TH_4621|M.thermoresistible__bu      PHGVRTMVGDLFAAGAAVDFAALYPSGRLVDAPLPTWTRRKLVLSRENGE
                                       :    .  .  *   .:             ***:. .:         

Mb2074c|M.bovis_AF2122/97           GVAADAAS------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        GVAADAAG------------------------------------------
MUL_2266|M.ulcerans_Agy99           AVPADAAG------------------------------------------
MLBr_00135|M.leprae_Br4923          DGTASVSG------------------------------------------
MMAR_3798|M.marinum_M               PTPATVSDPAEVALWDAVNDDAVDTVARVLRIDNAQSMVSLGPMVRALRE
Mflv_0405|M.gilvum_PYR-GCK          MA-IDGRV------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      TA-IEG--------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      IA-VDG--------------------------------------------
MAV_1763|M.avium_104                IAGIDG--------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       IR-SDG--------------------------------------------
TH_4621|M.thermoresistible__bu      QQTRGG--------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           ----LG--------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        ----LG--------------------------------------------
MUL_2266|M.ulcerans_Agy99           ----LG--------------------------------------------
MLBr_00135|M.leprae_Br4923          ----LG--------------------------------------------
MMAR_3798|M.marinum_M               WRKELGDRSVVGQLRYQVGWRNVTPNTFPQTRQRWLVLTLPEQSDDVWVA
Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
MAV_1763|M.avium_104                --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               GFSARFADSVAMLAIDPHMFDRNSLAALLADEATRNKCDGVVSFMALRER
Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
MAV_1763|M.avium_104                --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           ----------------------------------------------LAAS
Rv2048c|M.tuberculosis_H37Rv        ----------------------------------------------LAAS
MUL_2266|M.ulcerans_Agy99           ----------------------------------------------LQAG
MLBr_00135|M.leprae_Br4923          ----------------------------------------------LGST
MMAR_3798|M.marinum_M               THQDFRGISTALLSTLHITQAYGDSGLDLPLWVITQGGAQVNPDEDLTPS
Mflv_0405|M.gilvum_PYR-GCK          ----------------------------------------------GASA
MAB_0939|M.abscessus_ATCC_1997      ----------------------------------------------GGGL
MSMEG_0408|M.smegmatis_MC2_155      -----------------------------------------------GTA
MAV_1763|M.avium_104                ----------------------------------------------QGAA
Mvan_1003|M.vanbaalenii_PYR-1       ------------------------------------------------SS
TH_4621|M.thermoresistible__bu      ----------------------------------------------CTIT
                                                                                      

Mb2074c|M.bovis_AF2122/97           EHALLG--------------AVIDLPASGG--------------------
Rv2048c|M.tuberculosis_H37Rv        EHALLG--------------AVIDLPASGG--------------------
MUL_2266|M.ulcerans_Agy99           EHALLG--------------AVVELPASGG--------------------
MLBr_00135|M.leprae_Br4923          EHALLG--------------AVVERPDSGG--------------------
MMAR_3798|M.marinum_M               QSAVWGLGQSACLEHPTWWGGLVDLPVSPAPQDFNRLQAILTCQQSEDQL
Mflv_0405|M.gilvum_PYR-GCK          GSGILG--------------SGKDLASGDS--------------------
MAB_0939|M.abscessus_ATCC_1997      PSGILG--------------RGEDLASGDS--------------------
MSMEG_0408|M.smegmatis_MC2_155      ASGILG--------------SGKDLASGDT--------------------
MAV_1763|M.avium_104                ASGLLG--------------SAKELASGDS--------------------
Mvan_1003|M.vanbaalenii_PYR-1       GSGLLG--------------SAQDLASGDI--------------------
TH_4621|M.thermoresistible__bu      VHPLLG--------------THVRLPEEPER-------------------
                                       : *                   .                        

Mb2074c|M.bovis_AF2122/97           ---------------------------------VVLTGRLSPSVQGWLAD
Rv2048c|M.tuberculosis_H37Rv        ---------------------------------VVLTGRLSPSVQGWLAD
MUL_2266|M.ulcerans_Agy99           ---------------------------------VVLTGRLSLAAQGWLAD
MLBr_00135|M.leprae_Br4923          ---------------------------------VVLTGRLSLANQPWLAD
MMAR_3798|M.marinum_M               AIRAAGVSARRLHKASLPQDRMRTWKISGTALVTGVTGHLGQHIARWLAQ
Mflv_0405|M.gilvum_PYR-GCK          ----------------------------------VYTSRLSVKTQPWLSD
MAB_0939|M.abscessus_ATCC_1997      ----------------------------------VYISRLSVRSQPWLSD
MSMEG_0408|M.smegmatis_MC2_155      ----------------------------------IYTSRLSVKSQPWLAD
MAV_1763|M.avium_104                ----------------------------------VYTSRLSVKSQPWLAD
Mvan_1003|M.vanbaalenii_PYR-1       ----------------------------------VHTSRLSVKTQPWLSD
TH_4621|M.thermoresistible__bu      ---------------------------------HVWQADLGTGAQPWLAD
                                                                         . *.     **::

Mb2074c|M.bovis_AF2122/97           HSVAGVTIFP----------------------------------------
Rv2048c|M.tuberculosis_H37Rv        HSVAGVTIFP----------------------------------------
MUL_2266|M.ulcerans_Agy99           HAVGGVVIFP----------------------------------------
MLBr_00135|M.leprae_Br4923          HVIGGVVLFP----------------------------------------
MMAR_3798|M.marinum_M               AGASHLVLLSRTAAEHPQVAELEKELNSAGITTTSISVDVTDRDALAAVV
Mflv_0405|M.gilvum_PYR-GCK          HVIYGTVVVP----------------------------------------
MAB_0939|M.abscessus_ATCC_1997      HVIYGTVVVP----------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      HVIYGTVVVP----------------------------------------
MAV_1763|M.avium_104                HVIYGTVVVP----------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       HVIYGTVVVP----------------------------------------
TH_4621|M.thermoresistible__bu      HQIHTVAALP----------------------------------------
                                          . ..                                        

Mb2074c|M.bovis_AF2122/97           -----GAGFVELAIRAGDEVGCGVVDELTLAAPLVLPASGSVAVQVVVNG
Rv2048c|M.tuberculosis_H37Rv        -----GAGFVELAIRAGDEVGCGVVDESTLAAPLVLPASGSVAVQVVVNG
MUL_2266|M.ulcerans_Agy99           -----GAGFVELAIRAGDEVGCRVVDELTLAAPLVLPSGGSVAVQVVVGS
MLBr_00135|M.leprae_Br4923          -----GAGFVELVIRAGDEVGCAGVEELVLAAPLVLHPGSGVQVQVVVAA
MMAR_3798|M.marinum_M               AETRIEHGPIHTVVHAAAHIGLVTTAETTIDEFIKSFAAKALGAENLIAV
Mflv_0405|M.gilvum_PYR-GCK          -------GATYAAMALAAVGTPAHAKDVFFYEPIILPEKSSREVQLTVHP
MAB_0939|M.abscessus_ATCC_1997      -------GATYAAMALAAVGTPARAKDVFFYEPIILPEKSSREVQLTLHP
MSMEG_0408|M.smegmatis_MC2_155      -------GATYAAMALAAVGTPARLKDVFFYEPIILPEKASREVQLTLHP
MAV_1763|M.avium_104                -------GATYAAMALAAVGPPARVQNVYFYEPIILPDKASREVQLSLHP
Mvan_1003|M.vanbaalenii_PYR-1       -------GATYAAMALAAMPTPARVQEVFFYEPIILGDKDSREVQLMLHR
TH_4621|M.thermoresistible__bu      -------GAAYCEMALAAAREVIDSDGVEVRDVRFEQMLLLDEQTEVSAV
                                           *     :  .            .                    

Mb2074c|M.bovis_AF2122/97           PDESGVRGVSVYSR-GDVGTG-WVLHAEGALRA------------GSAEP
Rv2048c|M.tuberculosis_H37Rv        PDESGVRGVSVYSR-GDVGTG-WVLHAEGALRA------------GSAEP
MUL_2266|M.ulcerans_Agy99           PDDSGARAVSVYSR-GDAGSD-WVLHAEGSLGS------------GSPEP
MLBr_00135|M.leprae_Br4923          ADESSRRAVSVYSR-GDQSHGGWLLNAEGLLEV------------DAAEA
MMAR_3798|M.marinum_M               LEDQPPQTFIMFSS-AAATWGGTRQGAYAAANAYIEALVTRLRGRGCRAI
Mflv_0405|M.gilvum_PYR-GCK          SVDGE-SKFQVHSRPYGERGAEWALNAEGVVASGVGD---SPAAAGDLED
MAB_0939|M.abscessus_ATCC_1997      LEDGSGSKFQVHSRPYGERDVDWSLNAEGTVVTGIGDDAEPAPEAAEPAE
MSMEG_0408|M.smegmatis_MC2_155      ADGGSVLSFQIHSRPYGERGADWSLNAEGTVDTAGSD---PDAAADEQSD
MAV_1763|M.avium_104                LQEGG-WSFRVDSRPYGVPDAEWSLNADGTVVAGIED-----EPAADPAD
Mvan_1003|M.vanbaalenii_PYR-1       TDDADGWTFEVHSRPYGDRDADWSRNASGTVAAGVGD-----AAPDAAAD
TH_4621|M.thermoresistible__bu      ASAVEPGTLEFAVETAKDGEHERRATAVLGAADDTEP--------PQAHD
                                            . .               *                       

Mb2074c|M.bovis_AF2122/97           TADLAMWPPAGAVPVEVADGYQQLAERGYG--------------------
Rv2048c|M.tuberculosis_H37Rv        TADLAMWPPAGAVPVEVADGYQQLAERGYG--------------------
MUL_2266|M.ulcerans_Agy99           ATDLSTWPPVGAVEVENADGYQQLAERGYG--------------------
MLBr_00135|M.leprae_Br4923          TVDLSLWPPEGAESVDISDAYPQLAERGYA--------------------
MMAR_3798|M.marinum_M               APAWGAWTDDRTTTQEVVGYFSRIGLNQISPDIAFAALQQSLDVDDTLIT
Mflv_0405|M.gilvum_PYR-GCK          PVDEAIERLNRMRPQELFETFADLELAWGP--------------------
MAB_0939|M.abscessus_ATCC_1997      PVDAAIERMERMRPMELFEIFADLELAWGP--------------------
MSMEG_0408|M.smegmatis_MC2_155      PVDEVIERLERMRPQDLFETFADLELAWGP--------------------
MAV_1763|M.avium_104                HIDAVIERLDRNRPQLLFDSFAESELEWGT--------------------
Mvan_1003|M.vanbaalenii_PYR-1       PVDNAIERLTRTRPQQLFDAFADNDLAWGP--------------------
TH_4621|M.thermoresistible__bu      IDALLAEHPTRIEGDELRQWFDQRGVQFGP--------------------
                                                        :                             

Mb2074c|M.bovis_AF2122/97           ----YGPAFRGLTAMWRRGDEVFAEVALPADAGVSVTGF---GVH-----
Rv2048c|M.tuberculosis_H37Rv        ----YGPAFRGLTAMWRRGDEVFAEVALPADAGVSVTGF---GVH-----
MUL_2266|M.ulcerans_Agy99           ----YGPAFRGLNAMWRRGDEVFAEVALPADAGVSVSGF---GIH-----
MLBr_00135|M.leprae_Br4923          ----YGPAFQGLVAIWRRGSELFAEVVAPT--GVVVDGM---GMH-----
MMAR_3798|M.marinum_M               IADVDWSQFRDVFTTTGRAHALLAELGTSQPQTAEIPAI---AENSHFAA
Mflv_0405|M.gilvum_PYR-GCK          ------TWSGSLKSLWLGEGEAIGDILVGAELAEQLGTE---PMH-----
MAB_0939|M.abscessus_ATCC_1997      ------TWSGSLKSLWLGEGEAIGDVLVGEELAEQLGTE---PMH-----
MSMEG_0408|M.smegmatis_MC2_155      ------TWSGSLKSLWLGDGEAVGDILVGAELAEQLGSE---PMH-----
MAV_1763|M.avium_104                ------TWSTSLKSLWMGDGEAVGDVTVGDELAEHLGTE---PMH-----
Mvan_1003|M.vanbaalenii_PYR-1       ------AWCSSLRSLWVGTGEAVGDIAVGAELGEHLGRE---PIH-----
TH_4621|M.thermoresistible__bu      ----AFTGLTAARIPEGTVTSVLAEVGLPGQIRSQQAPYGIH--------
                                          .               ..::                        

Mb2074c|M.bovis_AF2122/97           ------------------------------PVLLDAALHAVVLSAESAER
Rv2048c|M.tuberculosis_H37Rv        ------------------------------PVLLDAALHAVVLSAESAER
MUL_2266|M.ulcerans_Agy99           ------------------------------PVMLDAALHAVILASDGADD
MLBr_00135|M.leprae_Br4923          ------------------------------PALLDAVLHALGLAIENTQA
MMAR_3798|M.marinum_M               QLAKQAPQQQLATLIGLVTNVTAAVLAHPDPAVLDPDLSFKDLGIDSLSA
Mflv_0405|M.gilvum_PYR-GCK          ------------------------------PVLMDLCTGVAFPAFPALLA
MAB_0939|M.abscessus_ATCC_1997      ------------------------------PVLMDLCTGVAFPAFPALLA
MSMEG_0408|M.smegmatis_MC2_155      ------------------------------PVLMDLCTGVAFPAFPALLA
MAV_1763|M.avium_104                ------------------------------PVLLDLCTGVVFPAFPALLA
Mvan_1003|M.vanbaalenii_PYR-1       ------------------------------PVLLDLCTGIAGAALLAAAA
TH_4621|M.thermoresistible__bu      ------------------------------PALLDACFQSVAAHPDVQGA
                                                                  *.::*               

Mb2074c|M.bovis_AF2122/97           G-------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        G-------------------------------------------------
MUL_2266|M.ulcerans_Agy99           FGVP----------------------------------------------
MLBr_00135|M.leprae_Br4923          T-------------------------------------------------
MMAR_3798|M.marinum_M               LELRNTLTRDTGLTLPATVVFDHPTPTAVAEHLLGLLSGVTGPTLAVVPT
Mflv_0405|M.gilvum_PYR-GCK          AEQG----------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      AEQG----------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      AEQG----------------------------------------------
MAV_1763|M.avium_104                AEQG----------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       QTDA----------------------------------------------
TH_4621|M.thermoresistible__bu      G-------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               RVGVDVPVAVVGMACRLPGGIESAAGLWDVVSNGIDVMSGFPLDRGWDVA
Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
MAV_1763|M.avium_104                --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           --------------------------------------------QGSVLV
Rv2048c|M.tuberculosis_H37Rv        --------------------------------------------QGSVLV
MUL_2266|M.ulcerans_Agy99           --------------------------------------------EGSVLV
MLBr_00135|M.leprae_Br4923          ---------------------------------------------TEMRL
MMAR_3798|M.marinum_M               GLFDPDPDAEGKTYTRYGGFVADVAGFDAEFFGISAREAITMDPQQRVLL
Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------VNDLYL
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------VNDLFL
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------VNDLFL
MAV_1763|M.avium_104                --------------------------------------------FNDLLL
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------DPELFL
TH_4621|M.thermoresistible__bu      ---------------------------------------------SGLLL
                                                                                   : :

Mb2074c|M.bovis_AF2122/97           PFSWQGVSLHAAGASAVRAR------------------------IAPVGP
Rv2048c|M.tuberculosis_H37Rv        PFSWQGVSLHAAGASAVRAR------------------------IAPVGP
MUL_2266|M.ulcerans_Agy99           PFAWQGVTLHAAGASAVRAR------------------------IAPAGP
MLBr_00135|M.leprae_Br4923          PFCWRGVSLHAGGAGRVRAR------------------------FTSAGA
MMAR_3798|M.marinum_M               EVCWQALEHAGIDPTTLEGSDTGVFVGIGAQSYVSGHSGVEGYALTGASA
Mflv_0405|M.gilvum_PYR-GCK          PLRYGQVSLQEKMPRRFYCR----------------ATWHEAPLDSETQV
MAB_0939|M.abscessus_ATCC_1997      PLRYGQVTLKEKMPRRFYCR----------------ARWHESPLDSETQV
MSMEG_0408|M.smegmatis_MC2_155      PLRYGQVTLAEKMPRRFYCR----------------ARWHRSALDSETQV
MAV_1763|M.avium_104                PLRYGQVSLREKMPRRFYCR----------------GKWRPSALDSETQV
Mvan_1003|M.vanbaalenii_PYR-1       PLRYGRVEVRERMPRRFYCR----------------ARWQTGGIDSETQV
TH_4621|M.thermoresistible__bu      PLGVRRLQAFGPTRGARYCYAR------------------VTDADGSKAE
                                     .    :                                           

Mb2074c|M.bovis_AF2122/97           SAVSIELADGLGLP-------VLSVASMLARPVTDQQLR-----------
Rv2048c|M.tuberculosis_H37Rv        SAVSIELADGLGLP-------VLSVASMLARPVTDQQLR-----------
MUL_2266|M.ulcerans_Agy99           SAVSIELSDGLGLP-------VLSVASMLARPVTDQQLR-----------
MLBr_00135|M.leprae_Br4923          DAIAVDIADSAGLP-------VLTVRSLVTRAMTAEQLR-----------
MMAR_3798|M.marinum_M               SVASGRVAYVLGLQGPAITVDTACSSSLVATHLACQSLRNGESSLALAGG
Mflv_0405|M.gilvum_PYR-GCK          FDLEYLDRDGRHLGGVREFTVKRAPREALLRGLGGDATRLLYTLG-----
MAB_0939|M.abscessus_ATCC_1997      FDLDYLDRDGRHLGGIREFTVKRAPREALLRGLGGDATRLLYTLG-----
MSMEG_0408|M.smegmatis_MC2_155      FELEFVDLGGRALGGIREFTVKRAPREALLRGLGGDATRLLYTLG-----
MAV_1763|M.avium_104                FDIDFIDRDGRHLGGIREFTVKRAPREALLRGLGGDATRLLYTLG-----
Mvan_1003|M.vanbaalenii_PYR-1       FDLDFLDHDGRNLGGIREFTVKRAPREALLRGLGADATRLIYRVG-----
TH_4621|M.thermoresistible__bu      ADLDVLDEHGNVLLRVQGLLMGGAAADGDDRDRVLGERLLTIEWQ-----
                                                *             .                       

Mb2074c|M.bovis_AF2122/97           -----------------------------AAVSSSG---------PDRLF
Rv2048c|M.tuberculosis_H37Rv        -----------------------------AAVSSSG---------PDRLF
MUL_2266|M.ulcerans_Agy99           -----------------------------AAVSGAG---------PDRLF
MLBr_00135|M.leprae_Br4923          -----------------------------TAVTAAGG------ALEQGPM
MMAR_3798|M.marinum_M               ATIMATPTPFIEFARQRGLAADGRCKAFAAAADGTGWGEGAAVLVLERLS
Mflv_0405|M.gilvum_PYR-GCK          ---------------------------WHEVPVP----ESGDGAAPQGTW
MAB_0939|M.abscessus_ATCC_1997      ---------------------------WHEVAVPPVAGEGEESAASIGTW
MSMEG_0408|M.smegmatis_MC2_155      ---------------------------WHEVPPP------PSADDAVGTW
MAV_1763|M.avium_104                ---------------------------WHEVPPQP---SNDGVANPSGTW
Mvan_1003|M.vanbaalenii_PYR-1       ---------------------------WRETSPPVR---DDGALGPSSTW
TH_4621|M.thermoresistible__bu      ----------------------------RRDLPEADSAAGKWLLVSTSAT
                                                                                      

Mb2074c|M.bovis_AF2122/97           EVTWSPQPSAAVEP---LPVCAWGTTEDS---------------------
Rv2048c|M.tuberculosis_H37Rv        EVTWSPQPSAAVEP---LPVCAWGTTEDS---------------------
MUL_2266|M.ulcerans_Agy99           GVDWTAQPSAELQP---VPVRIWGTVESEG--------------------
MLBr_00135|M.leprae_Br4923          DLVWSPIPLSSDGHGGGLPSVVSWADYCAG--------------------
MMAR_3798|M.marinum_M               DARRNRHPVLAVIAGSAVNQDGASNGLSAP--------------------
Mflv_0405|M.gilvum_PYR-GCK          LIGGFDELAVSVPG--CIPADR-TNPESLR-------------QLLTDAH
MAB_0939|M.abscessus_ATCC_1997      LIAGFDELAAKVPG--CIPLNRETDPELLG-------------EVLVAAK
MSMEG_0408|M.smegmatis_MC2_155      LIAGFDELAAKVPG--CVPIDRNTDLQVLG-------------EVLSQAH
MAV_1763|M.avium_104                LIAGFDELGAQLPG--CIPFDRNTDPESFG-------------QLLARAE
Mvan_1003|M.vanbaalenii_PYR-1       LVAGLDALADDVPGSIRIGFDRIWDPDRDGRVVLDPADDEHWRRLFALAD
TH_4621|M.thermoresistible__bu      ADVSATRLSDALKQAGAESTSMCWPQQADHADN---------------VD
                                                                                      

Mb2074c|M.bovis_AF2122/97           ------AAVVFESVPLAG------DVVAGVYAATSS--------------
Rv2048c|M.tuberculosis_H37Rv        ------AAVVFESVPLAG------DVVAGVYAATSS--------------
MUL_2266|M.ulcerans_Agy99           -DDDPGASVVFESVPQAG------EVVAGVYAATAA--------------
MLBr_00135|M.leprae_Br4923          -RGNDTGVVVWEFGSASAGAQAPVDSVAAVYSATHA--------------
MMAR_3798|M.marinum_M               -NGPAQQRVISQALANAGLPFTHVDVVEAHGTGTTLGDPIEAGALIATYG
Mflv_0405|M.gilvum_PYR-GCK          GRGLPFSGVVWRAARSDGDES--DAEVAARLEAEIAE-------------
MAB_0939|M.abscessus_ATCC_1997      ERGVPFSGVVWRAAGPGATES--TTESAARLEGEIAH-------------
MSMEG_0408|M.smegmatis_MC2_155      ARGAGFSGVVWRCATPGRKESGSASAESARLEAEITN-------------
MAV_1763|M.avium_104                DRGGPVTGIVWRATQSGGRES--SAESVARLETEIAG-------------
Mvan_1003|M.vanbaalenii_PYR-1       ERRAPVAGVVLGVTGRARPEE-PSADFAARLEAQIRD-------------
TH_4621|M.thermoresistible__bu      RFRAGIADGVTGVVVLTGPKNGNPDDAAARRGSDYVR-------------
                                             :                  .                     

Mb2074c|M.bovis_AF2122/97           --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               THRDPEHPLWLGSVKSNIGHTQHAAGAAGLIKMIQALNHAVLPATLHIDQ
Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
MAV_1763|M.avium_104                --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           -------------VLDVLQSWLT-----RDGAGVLVVMTRGAVALPGEDV
Rv2048c|M.tuberculosis_H37Rv        -------------VLDVLQSWLT-----RDGAGVLVVMTRGAVALPGEDV
MUL_2266|M.ulcerans_Agy99           -------------VLEVLRSWLS-----RDGAGQLIITTRGAVALPDEDV
MLBr_00135|M.leprae_Br4923          -------------ALQVLQFWFG-----QDRAGTLVVLTRGAVGLVGEGI
MMAR_3798|M.marinum_M               PSPHIDWSTDTVRLLTEATPWPE-----TEHLRTGAVSAFGVSGTNAHLI
Mflv_0405|M.gilvum_PYR-GCK          -------------LLGAVHTVQ---GGEVKLPGGLWIVTERAVATESGEP
MAB_0939|M.abscessus_ATCC_1997      -------------LLSAVHTVQNSAQNGVKLPGGLWIVTERAVATESGEP
MSMEG_0408|M.smegmatis_MC2_155      -------------LLSAVHAAQ---GPSVKLPGGLWIVTEHGVACESGEP
MAV_1763|M.avium_104                -------------LLTAVHALQNADGSAVKLPGGLWIVTERGVATESGEP
Mvan_1003|M.vanbaalenii_PYR-1       -------------VLGAVHSLS---ALGAKPAAGLWIVTERAVAAEAGEP
TH_4621|M.thermoresistible__bu      ----------------HLVRITRELAEIDGDAPRLFVVTRGAQAVLPQDR
                                                                        : :    .      

Mb2074c|M.bovis_AF2122/97           TDLAGAAVWGLVRSAQTEHPG-----------------------------
Rv2048c|M.tuberculosis_H37Rv        TDLAGAAVWGLVRSAQTEHPG-----------------------------
MUL_2266|M.ulcerans_Agy99           TDLAGSAVWGLVRSAQTEHPG-----------------------------
MLBr_00135|M.leprae_Br4923          SDLAAAAVWGMVRSAQSEHSG-----------------------------
MMAR_3798|M.marinum_M               VQQAPPEVFESVPEPETARPSGQPLLRIWPVSAHTPAALTAQAERLSEYL
Mflv_0405|M.gilvum_PYR-GCK          VDPVQAALWGFGRTAINEEPA-----------------------------
MAB_0939|M.abscessus_ATCC_1997      VDPVQAALWGFGRTTINEEPA-----------------------------
MSMEG_0408|M.smegmatis_MC2_155      VDPVQAALWGFGRTTINEEPA-----------------------------
MAV_1763|M.avium_104                VDPVQAALWGLGRTIVNEEPA-----------------------------
Mvan_1003|M.vanbaalenii_PYR-1       VDPVQSALWGLGRTLIAEEPG-----------------------------
TH_4621|M.thermoresistible__bu      PNLEQAGLRGLLRVIGAEHPH-----------------------------
                                     :   . :          ..                              

Mb2074c|M.bovis_AF2122/97           --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               TRHEDLSLTDLAYSLACTRTHHPYRAAVTVPVDTSNPGHDLAAALRALAA
Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
MAV_1763|M.avium_104                --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               NQPHPYVTCHHYRARQPSKTVFVFPGQGGQYPAMAAELYRQHPGFATAVD
Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
MAV_1763|M.avium_104                --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               ECDAELRPYTGWSVRDVICQDPDAPSLELVEVIQPVLFAVMIALAETLRG
Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
MAV_1763|M.avium_104                --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           -----RIVLVDSDAPLDDSALAAVVTTGE----PQVLWRRGEVYTARVHG
Rv2048c|M.tuberculosis_H37Rv        -----RIVLVDSDAPLDDSALAAVVTTGE----PQVLWRRGEVYTARVHG
MUL_2266|M.ulcerans_Agy99           -----RIVLVDTDAQLDEHAVAAVLAAGE----PQVLWRNGEVYTARVHG
MLBr_00135|M.leprae_Br4923          -----KIVLIDTDSAVD---VAVLADLGE----SQLLVRCNTVHAARLS-
MMAR_3798|M.marinum_M               YGIVPDAVIGHSQGEIAAAYIAGALTLAE----AAKVVALRSAALAQLAG
Mflv_0405|M.gilvum_PYR-GCK          ----LRCRLVDCDGSPQAVQALAALLSTP-VDEPELAVRQGKLLASRLLP
MAB_0939|M.abscessus_ATCC_1997      ----LRAKLVDGDGSPEAVQALARLLVTP-VDEPEIAVRQGKLLASRLLP
MSMEG_0408|M.smegmatis_MC2_155      ----LHCRLVDCDGSSEAVDLLAALLAAPGIQEPEIAVRQGKLLASRLLP
MAV_1763|M.avium_104                ----LRCRLVDSDGSEQAVRSLAGLLGAP-LDEPELAVRQGKLLASRLLP
Mvan_1003|M.vanbaalenii_PYR-1       ----LRCLLVDLDGSEDAGPALARLLGAP-GDEPELALRQGRLLVPRLLP
TH_4621|M.thermoresistible__bu      ----LRTTQIDIADDADLDRVAVQLLGGG--AEDETAWRDGQWYTARLSL
                                              .                                  .::  

Mb2074c|M.bovis_AF2122/97           SRAVGGLLVPPSDR-----PWRLAMSTA---------------------G
Rv2048c|M.tuberculosis_H37Rv        SRAVGGLLVPPSDR-----PWRLAMSTA---------------------G
MUL_2266|M.ulcerans_Agy99           SRAVAGLLVPPGDG-----PWRLGMSTA---------------------G
MLBr_00135|M.leprae_Br4923          -PAPQLLALPVGES-----MWRLAADGG---------------------G
MMAR_3798|M.marinum_M               TGTMASVLLSPEELRPLLQPWNTQISIAAINGPAHTIISGDTTAVEQFIG
Mflv_0405|M.gilvum_PYR-GCK          WSRSGHLTVPRGGD------YVLAPTER---------------------G
MAB_0939|M.abscessus_ATCC_1997      WSRTGHLTVPRGSD------YVLAPTER---------------------G
MSMEG_0408|M.smegmatis_MC2_155      WARSGHLTLPRGGD------FVLAPTER---------------------G
MAV_1763|M.avium_104                WARSGHLAVPRGTD------YVLAPTER---------------------G
Mvan_1003|M.vanbaalenii_PYR-1       WSRSGQLAIPRGTD------YVLAPTER---------------------G
TH_4621|M.thermoresistible__bu      SPLRPEERKQAVVDCERDGMRLEIRTPGDLET------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           TFEN----------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        TFEN----------------------------------------------
MUL_2266|M.ulcerans_Agy99           TFEN----------------------------------------------
MLBr_00135|M.leprae_Br4923          TLED----------------------------------------------
MMAR_3798|M.marinum_M               TCEDGGVQIRPIAVDYASHSAHVERLREHLLHELADLNPQPARIPLYSTV
Mflv_0405|M.gilvum_PYR-GCK          AIDN----------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      AIDN----------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      AIDN----------------------------------------------
MAV_1763|M.avium_104                AIDN----------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       VLDN----------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           --------------------------------------------LRLELI
Rv2048c|M.tuberculosis_H37Rv        --------------------------------------------LRLELI
MUL_2266|M.ulcerans_Agy99           --------------------------------------------LRLEPI
MLBr_00135|M.leprae_Br4923          --------------------------------------------LVIQPC
MMAR_3798|M.marinum_M               ASELSEHPLDTTAMDAEYWYRNLREPVEFYSCVAQLLAHSERVFVELSPH
Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------LRLTDS
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------LRITEK
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------LRLTET
MAV_1763|M.avium_104                --------------------------------------------LRLIEQ
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------LRVSET
TH_4621|M.thermoresistible__bu      --------------------------------------------MELAAF
                                                                                : :   

Mb2074c|M.bovis_AF2122/97           PDADAPLG---PGQVRVAVSAIAANFR--------DVMIALG--------
Rv2048c|M.tuberculosis_H37Rv        PDADAPLG---PGQVRVAVSAIAANFR--------DVMIALG--------
MUL_2266|M.ulcerans_Agy99           PDADAALQ---PGHVRVALSAMAANFR--------DVMIALG--------
MLBr_00135|M.leprae_Br4923          PEVQAPLQ---AGHMRVAVAAVGVNFR--------DVVAALG--------
MMAR_3798|M.marinum_M               PVLASALTDALADTGQLTQSAVVTTLRRDRPDM-DMVASAIANLHVHGHS
Mflv_0405|M.gilvum_PYR-GCK          EVPPPAEG-----YVQVRVEAAGLNFRDVLNVLG----------------
MAB_0939|M.abscessus_ATCC_1997      EVPAPDEG-----YVQVRVEAAGLNFRDVLNVLG----------------
MSMEG_0408|M.smegmatis_MC2_155      DVPEPDEG-----YVQVRVEAAGLNFRDVLNVLG----------------
MAV_1763|M.avium_104                EAPPPAEG-----CVQVRVEAGGLNFREVLNVLG----------------
Mvan_1003|M.vanbaalenii_PYR-1       EVTAPPEG-----HVQVRVEAAGLNFRDVLNALG----------------
TH_4621|M.thermoresistible__bu      DRVPPGPG-----QIEVAVTASSINFADVLIAFG----------------
                                        .          .:   *   .:                        

Mb2074c|M.bovis_AF2122/97           -----LYP-------------------DPDAVMGVEACG----------V
Rv2048c|M.tuberculosis_H37Rv        -----LYP-------------------DPDAVMGVEACG----------V
MUL_2266|M.ulcerans_Agy99           -----LYP-------------------DPDAAMGVEGAG----------V
MLBr_00135|M.leprae_Br4923          -----MYP-------------------GQAPPLGAEGAG----------V
MMAR_3798|M.marinum_M               PSWQKIYPGATTVELPTYPFQHRRYWLDPAPRADVSAAGLDQPEHPLLAA
Mflv_0405|M.gilvum_PYR-GCK          -----LYP-------------------GDPGPIGGDFAG----------T
MAB_0939|M.abscessus_ATCC_1997      -----LYP-------------------GDPGPIGGDFAG----------I
MSMEG_0408|M.smegmatis_MC2_155      -----LYP-------------------GDPGPIGGDFAG----------T
MAV_1763|M.avium_104                -----LYP-------------------GDPGPLGGDFAG----------T
Mvan_1003|M.vanbaalenii_PYR-1       -----LYP-------------------GDPGPIGGELAG----------V
TH_4621|M.thermoresistible__bu      -----RYPTFD----------------GRRPQLGTDFAG----------V
                                          **                   .     . . .*           

Mb2074c|M.bovis_AF2122/97           VIETSLNKGSFAVG------------------------DRVMGLFPEGTG
Rv2048c|M.tuberculosis_H37Rv        VIETSLNKGSFAVG------------------------DRVMGLFPEGTG
MUL_2266|M.ulcerans_Agy99           VVETASPDGRFAVG------------------------DRVVGLFPEGTG
MLBr_00135|M.leprae_Br4923          VIEIGPEVTGVAVG------------------------DAVMG-FLGGAG
MMAR_3798|M.marinum_M               VTELADQDQIVLSGRLSTSAHRWLAGHQLGDTVVLPATALIDMALYAGEH
Mflv_0405|M.gilvum_PYR-GCK          VTQLGEGVTGLDVG------------------------QRVYGSMQGAFA
MAB_0939|M.abscessus_ATCC_1997      VTQLGEGVTGVEVG------------------------QRVYGSMQGAFG
MSMEG_0408|M.smegmatis_MC2_155      VTQLGAGVSGLEIG------------------------QRVYGSMQGAFA
MAV_1763|M.avium_104                VTQLGSGVTGLEVG------------------------TRVYGFMQGAFA
Mvan_1003|M.vanbaalenii_PYR-1       VTAPGPDVDGFDVG------------------------QRVFGFAVGAFA
TH_4621|M.thermoresistible__bu      VTAVGPDVTSHRVG-----------------------DRVGGLSPNGCWS
                                    *   .        *                                    

Mb2074c|M.bovis_AF2122/97           TVASTDQRLLVKVPAGWSHTAAATTSVVFATAHYALVDLADVQPGQRVLI
Rv2048c|M.tuberculosis_H37Rv        TVASTDQRLLVKVPAGWSHTAAATTSVVFATAHYALVDLAAARSGQRVLI
MUL_2266|M.ulcerans_Agy99           TIAITDHRLLVKIPAGWSDTAAATTSVVFATAFYALRDLASVQPGQRILV
MLBr_00135|M.leprae_Br4923          PLAVVHQQLITQMPQGWSLAEAAAVPVVFLTALFGLADLAGIRAGESVLI
MMAR_3798|M.marinum_M               TGCPTIDELVLQTPLTLTPDAATDLQISVAAPDEQNRRTFSVHARTSEHP
Mflv_0405|M.gilvum_PYR-GCK          SRFNVPGQFLAPIPDGVSAVEAATIPAAALTVR-LSFDWAQVKSGDKVLI
MAB_0939|M.abscessus_ATCC_1997      SRFNVPAQFLAPIPDGISGVEAATIPAAALTVR-LSFDWAQLKPGDKVLI
MSMEG_0408|M.smegmatis_MC2_155      SRFNVPAQFLAPIPDGIGAVEAATIPAAALTVR-LAFDWAQLKPGDKVLI
MAV_1763|M.avium_104                SRFNVPVQLLAPIPDGVSAVDAATIPAAALTAR-LAFDWAQLKPGDRVLI
Mvan_1003|M.vanbaalenii_PYR-1       SRVNVPVQFLAPVPEGISAVAAATTPAAVLTAG-LAFDWAALRAGDRVLI
TH_4621|M.thermoresistible__bu      TFVTCDADLAVPLPDGLTEGQAAAVSTAHATAWYGLHDLARLGAGEKVLI
                                    .       :    *       *:       :            .      

Mb2074c|M.bovis_AF2122/97           HAGTGGVGMAAVQLARHLG-----------------------LEVFATAS
Rv2048c|M.tuberculosis_H37Rv        HAGTGGVGMAAVQLARHLG-----------------------LEVFATAS
MUL_2266|M.ulcerans_Agy99           HAATGGVGMAAVQLARHWG-----------------------LEVFATAS
MLBr_00135|M.leprae_Br4923          HAGTGGVGMAAVQFARHWG-----------------------VEIFVTAS
MMAR_3798|M.marinum_M               HQHSTWVLHASGTLSNHPSRMFSPTTPFAAGRTPNAVDQDSFYEELAQHG
Mflv_0405|M.gilvum_PYR-GCK          HAASGGVGLAAVQMAQQCG-----------------------AEVYATAS
MAB_0939|M.abscessus_ATCC_1997      HAASGGVGLAAIQMAQQFG-----------------------AEVFATAS
MSMEG_0408|M.smegmatis_MC2_155      HAASGGVGLAAIQMAQQSG-----------------------AEVFATAS
MAV_1763|M.avium_104                HAASGGVGLAAIQLAQRHG-----------------------ATVFATAS
Mvan_1003|M.vanbaalenii_PYR-1       HAASGGVGLAAVQLARQRG-----------------------ATVFATAS
TH_4621|M.thermoresistible__bu      HSATGGVGLAAIAIARSVG-----------------------AQIYATAG
                                    *  :  *  *:  ::.  .                           .  .

Mb2074c|M.bovis_AF2122/97           K-GKWDTLRAMGFDDDHISDSRSLEFEDKFRAATGGRG-------FDVVL
Rv2048c|M.tuberculosis_H37Rv        K-GKWDTLRAMGFDDDHISDSRSLEFEDKFRAATGGRG-------FDVVL
MUL_2266|M.ulcerans_Agy99           K-GKWDTLRAMGFDEDHIGDSRSLEFEDKFRAATGGRG-------MDVVL
MLBr_00135|M.leprae_Br4923          R-GKWDTLRDMGFDDDHIGDSRTLEFEEKFLAVTDGRG-------VDVVL
MMAR_3798|M.marinum_M               V-RYDGAFRALHSLENNPSDTDTTCAEVALPADTDVDGYGIHPALLDAAL
Mflv_0405|M.gilvum_PYR-GCK          T-FKRATLRKLGVK--HVYDSRTTDFAEQILADTDGAG-------VDVVL
MAB_0939|M.abscessus_ATCC_1997      T-FKRATLRKLGVK--YVYDSRTTDFADQILADTDGAG-------VDVVL
MSMEG_0408|M.smegmatis_MC2_155      T-FKRSTLRRLGVK--YVYDSRTTDFADQILADTNGAG-------VDVVL
MAV_1763|M.avium_104                T-YKRATLRKLGVE--YVYDSRSTDFADQILADTDGAG-------VDVVL
Mvan_1003|M.vanbaalenii_PYR-1       G-YKRPMLRAMGVD--HVYDSRTTDFADQILADTDGAG-------VDVVL
TH_4621|M.thermoresistible__bu      SPARRDLLRDMGIE--HVYDSRSTAFADEIRRDTDGYG-------VDVVL
                                           :* :        *: :      :   *.  *       .*..*

Mb2074c|M.bovis_AF2122/97           DSLAGEFVDAS-----------------------------LRLVAPGGVF
Rv2048c|M.tuberculosis_H37Rv        DSLAGEFVDAS-----------------------------LRLVAPGGVF
MUL_2266|M.ulcerans_Agy99           DSLAGEFVDAS-----------------------------LRLVAPGGVF
MLBr_00135|M.leprae_Br4923          DSLAGDFVDAS-----------------------------LRLLVRGGRF
MMAR_3798|M.marinum_M               QPLAAAFTDTDTDAPSAATPRMPFVITGVNLHATGARRLLVQLTATDADT
Mflv_0405|M.gilvum_PYR-GCK          NSLTSEGFIEAT----------------------------LRATAQHGRF
MAB_0939|M.abscessus_ATCC_1997      NSLTSEGFIEAT----------------------------LRATAKNGRF
MSMEG_0408|M.smegmatis_MC2_155      NSLTSAGFVEAT----------------------------LKATAQGGRF
MAV_1763|M.avium_104                NSLTNEGFIEAT----------------------------VRATAQHGRF
Mvan_1003|M.vanbaalenii_PYR-1       NSLTNDGFVAAT----------------------------VRATARNGRF
TH_4621|M.thermoresistible__bu      NSLPGAAQRAG-----------------------------LELLSFGGRF
                                    :.*.                                    :.     .  

Mb2074c|M.bovis_AF2122/97           LEMGKTDIRDPGVIAQQ--------YPGVR-------YRAFDLFEAGPDR
Rv2048c|M.tuberculosis_H37Rv        LEMGKTDIRDPGVIAQQ--------YPGVR-------YRAFDLFEPGPDR
MUL_2266|M.ulcerans_Agy99           LEMGKTDIREAAVVAQQ--------HTGVR-------YRAFDLFEAGPDH
MLBr_00135|M.leprae_Br4923          LEMGKTDIRDAQEIAAN--------YPGVQ-------YRAFDLSEAGPVR
MMAR_3798|M.marinum_M               FSLHATDPAGATVITIN--------AVTLRALTDIGSLRTSGISRRGLLE
Mflv_0405|M.gilvum_PYR-GCK          AEIAKRDIWTVEQMAAA--------RPDLAY----EIVALDTVMFTEPDR
MAB_0939|M.abscessus_ATCC_1997      AEIAKRDIWTTEQMAQS--------RPDIAY----EIVALDTVMFQEPDR
MSMEG_0408|M.smegmatis_MC2_155      AEIAKRDIWSHEQMAEA--------RPDIAY----EIVALDTVMFTEPDR
MAV_1763|M.avium_104                VEIAKRDIWTREQMAAA--------RPDIAY----EIVALDWACVEQPEH
Mvan_1003|M.vanbaalenii_PYR-1       AEIAKRDIWSPEQMAAA--------RPDIDY----EVLALDAVMQQDPDR
TH_4621|M.thermoresistible__bu      IEIGKRDIYGDTRLGLFPFRRNLAFHG----------VDLGLMADSHPHK
                                     .:   *      :                                   .

Mb2074c|M.bovis_AF2122/97           IAQILAELATLFGDGVLRPLPVTT--------------------------
Rv2048c|M.tuberculosis_H37Rv        IAQILAELATLFGDGVLRPLPVTT--------------------------
MUL_2266|M.ulcerans_Agy99           IAQILAELAALFSEDVLRPLPVTT--------------------------
MLBr_00135|M.leprae_Br4923          MQEMLCEVRELFDTQVLHRLPVTS--------------------------
MMAR_3798|M.marinum_M               LAWPALPPDTFSTAAVLPPLALVSSHSDDLAHALGQSSQCTVYTDLAAVQ
Mflv_0405|M.gilvum_PYR-GCK          IRDLLTEVSAGLRDGAWTPLPAEV-------------------------Y
MAB_0939|M.abscessus_ATCC_1997      IRVLLTEVSEGLAKGEWTPLPAEI-------------------------Y
MSMEG_0408|M.smegmatis_MC2_155      IRDLLTEVSDGMARGEWTPLPAEI-------------------------Y
MAV_1763|M.avium_104                IHALLTEVSDGLASGEWRPLPAEI-------------------------Y
Mvan_1003|M.vanbaalenii_PYR-1       IQLLLADLADSLARGETAPLPFEA-------------------------Y
TH_4621|M.thermoresistible__bu      IRELLETVYRLTADGVLPMPQSTHYP------------------------
                                    :                                                 

Mb2074c|M.bovis_AF2122/97           -------FDVRRAP------------------------------------
Rv2048c|M.tuberculosis_H37Rv        -------FDVRCAP------------------------------------
MUL_2266|M.ulcerans_Agy99           -------FDVRRAP------------------------------------
MLBr_00135|M.leprae_Br4923          -------WDVRCAP------------------------------------
MMAR_3798|M.marinum_M               PCPPLVLWDLTAGPDPTPTPEDGDTEDPLQRVHTLTRHTLAGLQNWLNRS
Mflv_0405|M.gilvum_PYR-GCK          PLTEAR--------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      PLTEAR--------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      PITEAR--------------------------------------------
MAV_1763|M.avium_104                PLAEAK--------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       PLAEAT--------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           -------------------------------AALRYLSQARHTGKVVMLM
Rv2048c|M.tuberculosis_H37Rv        -------------------------------AALRYLSQARHTGKVVMLM
MUL_2266|M.ulcerans_Agy99           -------------------------------AALRYLSQARHVGKVVLTM
MLBr_00135|M.leprae_Br4923          -------------------------------AAFRFMSQARHIGKVVLTM
MMAR_3798|M.marinum_M               DTTGTHLVILTRRAVTTVPDDRSPDPAHAATWAFAHSAQNEHPNRITLID
Mflv_0405|M.gilvum_PYR-GCK          -------------------------------AAFRRMQQARHIGKIVVQI
MAB_0939|M.abscessus_ATCC_1997      -------------------------------TAFRRMQQARHIGKIVCQM
MSMEG_0408|M.smegmatis_MC2_155      -------------------------------SAFRRMQQARHIGKIVLQV
MAV_1763|M.avium_104                -------------------------------TAFRRMQQARHIGKIVLQM
Mvan_1003|M.vanbaalenii_PYR-1       -------------------------------TAFRRMQQARHTGKIILQM
TH_4621|M.thermoresistible__bu      --------------------------LAEAATAIRVMSAAEHVGKLVLDV
                                                                    *:      .* .::    

Mb2074c|M.bovis_AF2122/97           P-------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        P-------------------------------------------------
MUL_2266|M.ulcerans_Agy99           P-------------------------------------------------
MLBr_00135|M.leprae_Br4923          PS------------------------------------------------
MMAR_3798|M.marinum_M               IDNTPATSQTLTNILTTLTNPTSAPTEPQLALRHGTPHTPRLTPTTTETT
Mflv_0405|M.gilvum_PYR-GCK          PN------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      PN------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      PK------------------------------------------------
MAV_1763|M.avium_104                PK------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       PK------------------------------------------------
TH_4621|M.thermoresistible__bu      PHTG----------------------------------------RADVVV
                                                                                      

Mb2074c|M.bovis_AF2122/97           ------GSWAAGTVLITGGTGMAGSAVARHVVARHGVRNLVLVSRRGPDA
Rv2048c|M.tuberculosis_H37Rv        ------GSWAAGTVLITGGTGMAGSAVARHVVARHGVRNLVLVSRRGPDA
MUL_2266|M.ulcerans_Agy99           ------DAWAAGTVLITGGTGMAGSALARHVVAHHGVRQLVLVSRRGPDA
MLBr_00135|M.leprae_Br4923          ---ALADGLAEGTVLITGASGAIGGVLARHMVSAYGVRHLVLASRRGDRA
MMAR_3798|M.marinum_M               TTSPPLEFDPAGTVLITGGTGMLGAVFAEHMIARYGARHLLLVSRSGPDA
Mflv_0405|M.gilvum_PYR-GCK          ----PLQPQPDRSYLITGGLGAIG-LHTAGYLAQLGAGDIVLTSRRAPDA
MAB_0939|M.abscessus_ATCC_1997      ----PLAPRPDRTYLITGGLGAIG-LHTAAYLAQLGAGDIVLTSRRAPDT
MSMEG_0408|M.smegmatis_MC2_155      ----PLQPQQDRSYLITGGLGAIG-LHTAAYLAQLGAGDIVLTSRRDPDE
MAV_1763|M.avium_104                ----PLQPRGDRSYLITGGLGAIG-LHLAAYLAQLGAGEIVLTSRRAPDA
Mvan_1003|M.vanbaalenii_PYR-1       ----PLQPHGDRSYLITGGLGALG-LHAAAYLAQLGAGDIVLTGRRMPDA
TH_4621|M.thermoresistible__bu      PPEQASPFRSDGAYIVTGGMGGLG-LYLAGEMAAAGAGCIVLNGRSAPSG
                                                : ::**. *  *       ::  *.  ::* .*     

Mb2074c|M.bovis_AF2122/97           PGAAELVAELAAAGAQVQVVACDAADRAALAKVIADIPVQHP-LSGVIHT
Rv2048c|M.tuberculosis_H37Rv        PGAAELVAELAAAGAQVQVVACDAADRAALAKVIADIPVQHP-LSGVIHT
MUL_2266|M.ulcerans_Agy99           PGAAELAEELSAFGAQVQVVACDAADRAALAKLIADIPMQHP-LSAVIHT
MLBr_00135|M.leprae_Br4923          EGAVELAAELVGAGAKIQVVACDVADNDAVRGLFAQLSREFPPVRGVIHA
MMAR_3798|M.marinum_M               PGADDLYQRLTQLGAQITITACDASDPTALAAVLANIPTEHP-LRAVIHT
Mflv_0405|M.gilvum_PYR-GCK          AAQQAIADIADRTKARLHVFTADVGVEADVAALLERIRAELPPLAGVAHL
MAB_0939|M.abscessus_ATCC_1997      DAQRVIGEITERSKTRIHVFTADVGAESEVAGLLERIRAELPPLAGVAHL
MSMEG_0408|M.smegmatis_MC2_155      SAQRAIDEITERHKCRIHTYAADVGDEAQVADLLARIRAELPPLAGIAHL
MAV_1763|M.avium_104                AAWRAIDDITERYRCRVHTFAADVGDAAQVEQLLARIRAELPPLAGVAHL
Mvan_1003|M.vanbaalenii_PYR-1       ATERAISEIAERYHCRIHTFAADVGDESAVRDLLERIRTELPPLAGVAHL
TH_4621|M.thermoresistible__bu      EALRTIEQLRAAGTEVIVECGXXX--------------------------
                                         :          :                                 

Mb2074c|M.bovis_AF2122/97           AGALDDAVVMSLTPDRVDVVLRSKVDAAWHLHELTRDLDVSAFVMFSSMA
Rv2048c|M.tuberculosis_H37Rv        AGALDDAVVMSLTPDRVDVVLRSKVDAAWHLHELTRDLDVSAFVMFSSMA
MUL_2266|M.ulcerans_Agy99           AGALDDAVVTSLTPERIETVLRAKVDAAWNLHELTRDMDLSAFVMFSSMA
MLBr_00135|M.leprae_Br4923          AGVLDDGAITSLTPDRVDTVLRAKVDAAWNLHEATRDLDLLMFVLCSSIA
MMAR_3798|M.marinum_M               AAVIDDAVVTELTVEQLDMVLAAKADTAWHLHRLTADINLDVFVVFSAAA
Mflv_0405|M.gilvum_PYR-GCK          AGVLDDALLSQQSVERFRTALAPKAFGAVHLDRLTRVDDLDFFLVSSSVS
MAB_0939|M.abscessus_ATCC_1997      AGVLDDALLGQQSVERFRTTLAPKAFGAEYLDRLTKGDDLDFFIVSSSVS
MSMEG_0408|M.smegmatis_MC2_155      AGVLDDALLSAQNPERFRTTLAPKAYGASHLDRLTRDDDLDFFIVSSSVS
MAV_1763|M.avium_104                AGVLDDALLSQQSPERFRVALAPKAFGASYLDHATRTDDLDFFIVSSSVS
Mvan_1003|M.vanbaalenii_PYR-1       AGVLDDALLPQQSPERFRTTLAPKAFGAWHLHRLTRDTELEFFIVYSSGS
TH_4621|M.thermoresistible__bu      ------------RGQPVEVAVPTELRHADEHPDRRGAQLCDEFARGEQGA
                                                  : .  .: .:   *              *   .  :

Mb2074c|M.bovis_AF2122/97           GLVGSSGQANYAAANSFLDALAAHRRAHGLPAISLGWGLWDQASAMTSGL
Rv2048c|M.tuberculosis_H37Rv        GLVGSSGQANYAAANSFLDALAAHRRAHGLPAISLGWGLWDQASAMTGGL
MUL_2266|M.ulcerans_Agy99           GLVGSSGQGNYAAANSFLDGLAVHRQAHGLPAISLGWGLWDQASNMTGGL
MLBr_00135|M.leprae_Br4923          ATVGSPGQGNYSAANAFLDGLAAYRQAAGLAGTSLAWGLWEQPGGMNAHL
MMAR_3798|M.marinum_M               AVLGAPGLANYAAANAFLDALAHHRHHHGLPATSLAWGYWQTPG-IAAHL
Mflv_0405|M.gilvum_PYR-GCK          SLFGSPGQSNYATANAFLDGLVAQRRAQGLPATGVNFGPWARGGMASSEA
MAB_0939|M.abscessus_ATCC_1997      SLFGSPGQSNYATANALLDGLIAQRRAQGLPATGINFGPWGQGGMASSEA
MSMEG_0408|M.smegmatis_MC2_155      SLFGSPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQGGMASSEA
MAV_1763|M.avium_104                SLLGSPGQANYSTANAWLDGLVAARQARGLPATGVNLGPWAQGGMASSEA
Mvan_1003|M.vanbaalenii_PYR-1       SVLGSPGQANYATANAVLDGLVAHRKARGLPATGVNWGPWAQGGMATSDA
TH_4621|M.thermoresistible__bu      QRNQHRTDAGEGQRDAHPPGAVGHDQPD--PGALSDTGLDERGGQFPGVG
                                            .. .  ::   .     :     .     *     .   .  

Mb2074c|M.bovis_AF2122/97           ATVDFKRFARDGIVAMSSADALQLFDTAMIVDEPFMLPAHIDFAALKVKF
Rv2048c|M.tuberculosis_H37Rv        ATVDFKRFARDGIVAMSSADALQLFDTAMIVDEPFMLPAHIDFAALKVKF
MUL_2266|M.ulcerans_Agy99           AAVDFKRFARDGIVAMSSDEALGLLDTAMVLGEPFMLPAHIDFAALRVKF
MLBr_00135|M.leprae_Br4923          SSRDLARISRSGLAPMNPAQALELFDAALVIDHPFMVTALLDRAALDAQA
MMAR_3798|M.marinum_M               DTVSQARFTRNHLIPITTEHGLALFDAALACQQPNLVPAPLNTHTLARQA
Mflv_0405|M.gilvum_PYR-GCK          AAANISAQGLIPLEPSAALTAMAEVVANGTAQATVLKANWQRAAKVLGSS
MAB_0939|M.abscessus_ATCC_1997      ATANISAQGLIPLDPSAALAALAEVVANGTGQATILKANWQRAAKVLGSS
MSMEG_0408|M.smegmatis_MC2_155      ATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSA
MAV_1763|M.avium_104                ARANIGAQGLIPLEPTAALAALAEVVANGTGQATVIKANWQRAAKLLGGA
Mvan_1003|M.vanbaalenii_PYR-1       ARANLGAQGLIPLEPTAALNALGEIVAHGIASAVVLKANWQRAAKLLGAT
TH_4621|M.thermoresistible__bu      VQIPVADPG-VGIDHRGAVRVDSGVPAQQGVDGEVVRHRTLSSVRSGRSS
                                                :    .      . :        :              

Mb2074c|M.bovis_AF2122/97           DGGTLPPMFVDLINAPTRRQVDDSLAAAKSKSALAHRLHGLPEDEQHAVL
Rv2048c|M.tuberculosis_H37Rv        DGGTLPPMFVDLINAPTRRQVDDSLAAAKSKSALLQRLEGLPEDEQHAVL
MUL_2266|M.ulcerans_Agy99           DGGTLPPMFVDLINAPTRRQVDDSLAAAKSKSALLQRLEGLPEDEQHAIL
MLBr_00135|M.leprae_Br4923          QAGALPPLFSRLVRRSRRRQIEDPGDATQSKLALVQRLQGLAANRQLELL
MMAR_3798|M.marinum_M               RQGVLPAILSSLITTRRHATIG-------SVETLTAQLATQTPEQQLATL
Mflv_0405|M.gilvum_PYR-GCK          RPPILDLVLPSAVGEIT------------GDSELLKQLQEIPVPQRAGFV
MAB_0939|M.abscessus_ATCC_1997      RPPILDLVLPSAVGEVT------------GDSELLKQLMEIPVPQRAGFV
MSMEG_0408|M.smegmatis_MC2_155      RPPILDLVLPSAAGEAT------------GDSELLKQLMEIPIPQRAGFV
MAV_1763|M.avium_104                RPPILDLVLPSAVGEAS------------GDSELLKQLQEIPVAQRAAFI
Mvan_1003|M.vanbaalenii_PYR-1       RPPILDHVLPSAVAAGP------------GDSALLKQLQDVPEAQRGSFV
TH_4621|M.thermoresistible__bu      RWTAPGSRCGSGR-----------------------RYGGESCRRTTGPA
                                                                        :    .  .     

Mb2074c|M.bovis_AF2122/97           LDLVRSHIATVLGSASPEAIDPDRAFQDLGFDSLTAVEMRNRLKSATG--
Rv2048c|M.tuberculosis_H37Rv        LDLVRSHIATVLGSASPEAIDPDRAFQELGFDSLTAVEMRNRLKSATG--
MUL_2266|M.ulcerans_Agy99           LNLVRSHIATVLGNSSPDAIDPDRAFQELGFDSLTAVEMRNRLKSATG--
MLBr_00135|M.leprae_Br4923          VGVVCLQAAAVLGRPSPEDIDPNTKFQDLGFDSLTAVELRNRLKSATG--
MMAR_3798|M.marinum_M               TRLVTTATAAVLAHPDPATLEPDLPFKDLGIDSLSALELRNTLTRDTG--
Mflv_0405|M.gilvum_PYR-GCK          TEFLQKEVQNFLRLAQPPAATS--RFLDLGTDSLMAIELRNRLHSQFGGA
MAB_0939|M.abscessus_ATCC_1997      TEFLQREVQNFLRLAQPPAATS--RFLDLGTDSLMAIELRNRLHSQFGGK
MSMEG_0408|M.smegmatis_MC2_155      TEFLQREVQNFLRLASPPAASS--RFLDLGTDSLMAIELRNRLHSQFGGK
MAV_1763|M.avium_104                TEFLQREVQGFLRLAQPPAATS--RFLDLGTDSLMAVELRNRLHSQFGGA
Mvan_1003|M.vanbaalenii_PYR-1       TEHLQRELQQILGLAQPPAATG--RFLELGMDSLMAVELRNRLVGQFGSG
TH_4621|M.thermoresistible__bu      AGAAARRGRTRRRRRPRRPPPPPDRVRHRAGPAHGPVRR-----------
                                                             . . .  :  .:.            

Mb2074c|M.bovis_AF2122/97           LSLSPTLIFDYPNSAALAGYMRRELLGSSPQ-DTSAVAAGEAELQRIVAS
Rv2048c|M.tuberculosis_H37Rv        LALSPTLIFDYPNSAALAGYMRRELLGSSPQ-DTSAVAAGEAELQRIVAS
MUL_2266|M.ulcerans_Agy99           LALSPTLIFDYPNSAALAGYMHRELVGASPQSDTTAEAPGEAELQRVVAS
MLBr_00135|M.leprae_Br4923          LTLPPTVIFDHPTPTAVAEYVAQQMLKSRPA------ESGDETSQAVEPK
MMAR_3798|M.marinum_M               ASLPATLVFDHPTPSAIAQYLNIQLSGSSTT--SRVQDPEEIEMQNLIAK
Mflv_0405|M.gilvum_PYR-GCK          FTINATAVFDYPTIGGLAEYLVAQLPDAETPQAAP-------QSESEPGP
MAB_0939|M.abscessus_ATCC_1997      FTINATAVFDYPTIGGLAEYLVGQLPDADAESAEAPPAVESAEAESGAGP
MSMEG_0408|M.smegmatis_MC2_155      FTINATAVFDYPTIGGLAEYLVGQLPDAEAPETA----------------
MAV_1763|M.avium_104                FTINATAVFDYPTIGGLAEYLAGQLPDAESEPGAAVAANPNPGSETGTGE
Mvan_1003|M.vanbaalenii_PYR-1       FTITATAVFDYPTIGALAEYLAAQTPESTEEGTEMKTADPDGQPATVGHA
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           IPVKRLRQAGVLDLLLALANETETSGQDPALAPTAEQEIADMDLDDLVNA
Rv2048c|M.tuberculosis_H37Rv        IPVKRLRQAGVLDLLLALANETETSGQDPALAPTAEQEIADMDLDDLVNA
MUL_2266|M.ulcerans_Agy99           IPVKRLRQAGVLELLLALANETGGNGQAAVTAETSEEDLADMDLDALVNA
MLBr_00135|M.leprae_Br4923          VEEVSVHA------------------------------------------
MMAR_3798|M.marinum_M               IPAKQLIKSGVLNILREIADIEHSSSANEKQDNVATMNLDELLIALGDHK
Mflv_0405|M.gilvum_PYR-GCK          DVTE----------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      AAASDAVSELKE--------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
MAV_1763|M.avium_104                AEPEREAAPEPS--------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       DVVLQTS-------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           AFRNDDE
Rv2048c|M.tuberculosis_H37Rv        AFRNDDE
MUL_2266|M.ulcerans_Agy99           AFMNDDE
MLBr_00135|M.leprae_Br4923          -------
MMAR_3798|M.marinum_M               GENKNDH
Mflv_0405|M.gilvum_PYR-GCK          -------
MAB_0939|M.abscessus_ATCC_1997      -------
MSMEG_0408|M.smegmatis_MC2_155      -------
MAV_1763|M.avium_104                -------
Mvan_1003|M.vanbaalenii_PYR-1       -------
TH_4621|M.thermoresistible__bu      -------