For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_4621 | - | - | 100% (2016) | mycocerosic acid synthase |
| M. thermoresistible (build 8) | TH_2454 | - | 0.0 | 37.23% (1453) | PUTATIVE beta-ketoacyl synthase |
| M. thermoresistible (build 8) | TH_4458 | - | e-137 | 44.28% (664) | PUTATIVE putative Fatty acyl-AMP ligase FadD28_1 and polyketide |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1554c | pks5 | 0.0 | 69.25% (1821) | polyketide synthase pks5 |
| M. gilvum PYR-GCK | Mflv_3391 | - | 0.0 | 39.93% (1415) | beta-ketoacyl synthase |
| M. tuberculosis H37Rv | Rv1527c | pks5 | 0.0 | 69.30% (1821) | polyketide synthase pks5 |
| M. leprae Br4923 | MLBr_01229 | pks3 | 0.0 | 64.90% (1826) | mycocerosic acid synthase (polyketide synthase) |
| M. abscessus ATCC 19977 | MAB_3148c | - | 0.0 | 62.38% (1818) | polyketide synthase Pks5 |
| M. marinum M | MMAR_2340 | pks5 | 0.0 | 68.90% (1804) | polyketide synthase Pks5 |
| M. avium 104 | MAV_2370 | - | 0.0 | 70.12% (1807) | mycocerosic acid synthase |
| M. smegmatis MC2 155 | MSMEG_4727 | - | 0.0 | 65.11% (1820) | mycocerosic acid synthase |
| M. ulcerans Agy99 | MUL_2010 | mas | 0.0 | 66.32% (1808) | multifunctional mycocerosic acid synthase membrane-associated |
| M. vanbaalenii PYR-1 | Mvan_3124 | - | 0.0 | 39.89% (1429) | beta-ketoacyl synthase |
CLUSTAL 2.0.9 multiple sequence alignment
TH_4621|M.thermoresistible__bu -----------------------VNIVGDTPVNAVAVIGMACRLPGGIDS
MAV_2370|M.avium_104 -------------------------------MVPVAVIGMACRLPGAVDS
Mb1554c|M.bovis_AF2122/97 ------------------MGKERTKTVDRTRVTPVAVIGMGCRLPGGIDS
Rv1527c|M.tuberculosis_H37Rv ------------------MGKERTKTVDRTRVTPVAVIGMGCRLPGGIDS
MMAR_2340|M.marinum_M -------------------------------MTPVAVIGMACRLPGGIGS
MUL_2010|M.ulcerans_Agy99 ---------------------------MQKSATPVAIIGMGCRLPGGVDS
MLBr_01229|M.leprae_Br4923 --------------------------MRAANVTPVAVIGMACRLPGGIDS
MAB_3148c|M.abscessus_ATCC_199 ---------------------------------------MGCRLPGGIES
MSMEG_4727|M.smegmatis_MC2_155 --------------------------MTQNCVAPVAIIGMACRLPGAINS
Mflv_3391|M.gilvum_PYR-GCK MKTTFDRISAMSAEQRDKLAEQFEKASRVAGAEPIAVVGMGCRFPGGATD
Mvan_3124|M.vanbaalenii_PYR-1 MKTTFDRISAMSAEQRGKLAEQFEKASRVAGAEPIAVVGIGCRLPGGVTG
:.**:**. .
TH_4621|M.thermoresistible__bu PQRLWEALLRGDDMVTEIPVDRWDADDYFDPEPGVPGRTVSRWGAFLDDV
MAV_2370|M.avium_104 PERLWEALLRGDDFVTEIPPDRWDADEYYDPEPGVPGRSVSRWGAFIDDV
Mb1554c|M.bovis_AF2122/97 PDRLWEALLRGDDLVTEIPADRWDIDEYYDPEPGVPGRTDCKWGAYLDNV
Rv1527c|M.tuberculosis_H37Rv PDRLWEALLRGDDLVTEIPADRWDIDEYYDPEPGVPGRTDCKWGAYLDNV
MMAR_2340|M.marinum_M PEELWEALLRGDDLVTEIPADRWDADEYYDPEPGVPGRTVCKWGAFLDNV
MUL_2010|M.ulcerans_Agy99 PEKLWESLLRGDDLVSEIPPDRWDVDDYYDPEPGVPGRTVSRWGGFIDDV
MLBr_01229|M.leprae_Br4923 PQRLWEALLRGDDLVTEIPKERWDADLYYDPEPGVPGRSVSRWGAFLDDV
MAB_3148c|M.abscessus_ATCC_199 PEQFWQALLRGEDFITEVPPARWDLTEYYDPESGVPGKSPSKWGAFLEDV
MSMEG_4727|M.smegmatis_MC2_155 PQQLWEALLRGDDFVTEIPTGRWDAEEYYDPEPGVPGRSVSKWGAFLDDP
Mflv_3391|M.gilvum_PYR-GCK PDSYWKVLESGTNAVTEVPADRWDGDAYYDPDPMAPGRMPSKWGAYIDDM
Mvan_3124|M.vanbaalenii_PYR-1 PDSYWELLENGTDAITEVPADRWDGDAFYDPDPMAPGRMPTKWGAYLDDV
*: *: * * : ::*:* *** ::**:. .**: :**.::::
TH_4621|M.thermoresistible__bu AGFDPEFFGISEREAISIDPQQRLLLETSWEAMEHAGLTPADVEGSSTGV
MAV_2370|M.avium_104 AGFDPEFFGINEREATAMDPQHRLLLETSWEAMEHAGLTEERVADSRTGV
Mb1554c|M.bovis_AF2122/97 GDFDPEFFGIGEKEAIAIDPQHRLLLETSWEAMEHGGLTPNQMAS-RTGV
Rv1527c|M.tuberculosis_H37Rv GDFDPEFFGIGEKEAIAIDPQHRLLLETSWEAMEHGGLTPNQMAS-RTGV
MMAR_2340|M.marinum_M GDFDPEFFGITEKEAIAIDPQHRMLLETAWEAMEHGGLTPEQMAESLTGV
MUL_2010|M.ulcerans_Agy99 AGFDAEFFGVSEREATSIDPQHRQLLETAWEAIEHAGLDPASLSGSSTGV
MLBr_01229|M.leprae_Br4923 GGFDCDFFGMTEREAIAIDPQHRLLLETSWDAIEHAGLDPATLAGSATGV
MAB_3148c|M.abscessus_ATCC_199 GGFDADFFSINEREAVSIDPQHRVLLETSWQAVEHAGIDPRALAGSQTGV
MSMEG_4727|M.smegmatis_MC2_155 AAFDPEFFGITEREAAAIDPQHRLLLETAWEAVEHSGLNPAGLAGSATGV
Mflv_3391|M.gilvum_PYR-GCK AGFDAEFFGITPREAAAMDPQQRIVLEVAYEALENAGLAPDTVGDIRGAV
Mvan_3124|M.vanbaalenii_PYR-1 SGFDADFFGITPREAAAMDPQQRVLLEVAWEALENAGLAPDTLSETRTAV
. ** :**.: :** ::***:* :**.:::*:*:.*: : .*
TH_4621|M.thermoresistible__bu FVGLSHDDYALLTSDAGALEEAYGFTGSAFSMASGRIAYRLGVHGPAVTV
MAV_2370|M.avium_104 FIGLTHGDYQLLAADTRSVEGAYGFSGSNFSLASGRIAYALGVHGPALTV
Mb1554c|M.bovis_AF2122/97 FVGLVHTDYILVHADNQTFEGPYGNTGTNACFASGRVAYAMGLQGPAITV
Rv1527c|M.tuberculosis_H37Rv FVGLVHTDYILVHADNQTFEGPYGNTGTNACFASGRVAYAMGLQGPAITV
MMAR_2340|M.marinum_M FVGLNHGDYQFVHVDANTFDGPYGNTGTNSCFASGRISYAMRLHGPAVTV
MUL_2010|M.ulcerans_Agy99 FVGLSHEDYLVRSVLAGDLAGPYASTGLINSVASGRIAHTLGLHGPAMTV
MLBr_01229|M.leprae_Br4923 FVGLTHGDYELLSADCGATEGPYGFTGTSNSFASGRVAYTLGLHGPAVTV
MAB_3148c|M.abscessus_ATCC_199 FVGVTHNDYQLVAADAADLGGPYGFAGTNFCMASGRISYALGVHGPSLTV
MSMEG_4727|M.smegmatis_MC2_155 FMGLTHNDYAHLAADAKALEGPYGFTGTSFSLASGRIAYALGVHGPAITV
Mflv_3391|M.gilvum_PYR-GCK MLGVYYNEYQSASAGNPDTIDAYSATGNAHSVTVGRIAYLLGLKGPAVAV
Mvan_3124|M.vanbaalenii_PYR-1 MMGVYYTEYQNSSAGNPDTIDAYSATGNAHSVTVGRIAYLLGLKGPAVAV
::*: : :* .*. :* ..: **::: : ::**:::*
TH_4621|M.thermoresistible__bu DTACSSSLLAVHMACRSLQVGESDLALAGGAMVMLEPRKYTSASGLGMLS
MAV_2370|M.avium_104 DTACSSGLTAIHLACRSLHEGESDLALAGGATLALDPRKFSAGSAEGMLS
Mb1554c|M.bovis_AF2122/97 DTACSSGLTAIHLACRSLHDGESDIALAGGVYVMLEPRRFASGSALGMLS
Rv1527c|M.tuberculosis_H37Rv DTACSSGLTAIHLACRSLHDGESDIALAGGVYVMLEPRRFASGSALGMLS
MMAR_2340|M.marinum_M DTACSSSLYATHLACNSLSEGESDLAFAAGVYVMLEPRRFASGSAQNMLS
MUL_2010|M.ulcerans_Agy99 DTACSSGLLTVHLACRSLHEGESDLALAGGCALLLEPNGSVSLSSQGMLS
MLBr_01229|M.leprae_Br4923 DTACSSGLMAVHQARGSLDCGESDLALAGGVVVTLEPRKSVSGSLQGMLS
MAB_3148c|M.abscessus_ATCC_199 DAGCAAGLATVHMGCQSLAAGESDLVLAGGVNLVLEPRRYVGASQQRMLS
MSMEG_4727|M.smegmatis_MC2_155 DTACSSSLSAIHMACRSLHDGESDVALAGGVSVLLEPRKAAGGSAAGMLS
Mflv_3391|M.gilvum_PYR-GCK DTACSSSLVSIHLACQSLRMRESDLALAGGVSLSLRPETQLALGKWGMLS
Mvan_3124|M.vanbaalenii_PYR-1 DTACSSSLVSIHLACHSLRMRESDLALAGGVSLNLRPETQLALAKWGMLS
*:.*::.* : * . ** ***:.:*.* : * *. . . ***
TH_4621|M.thermoresistible__bu PTGRCHAFDVAADGFVRSEGSVMLLLKRLPDALRDNDRILAVVRGTAANQ
MAV_2370|M.avium_104 PTGRCHAFDVAADGFVGGEGSVMLLLKRLNDALRDGDRILAVVRGTAANQ
Mb1554c|M.bovis_AF2122/97 ATGRCHAFDVSADGFVSGEGCVMLALKRLPDALADGDRILAVIRGTAANQ
Rv1527c|M.tuberculosis_H37Rv ATGRCHAFDVSADGFVSGEGCVMLALKRLPDALADGDRILAVIRGTAANQ
MMAR_2340|M.marinum_M PTGHCHAFDVDADGFVSGEGSVVLLLKRLADAQRDGDRILAVMRGTAANQ
MUL_2010|M.ulcerans_Agy99 PTGRCHAFDVDADGFVRSEGCAVVVLKRLSDALADGDRILAVVRGTAANQ
MLBr_01229|M.leprae_Br4923 PTGRCHAFDVAADGFVSGEGCVVLLLKRMPDAERDGDRILAVLRGTAANQ
MAB_3148c|M.abscessus_ATCC_199 PTGRCHTFTGEADGFVMSEGCVMVLLKRLDDAVRDGDRILAVVRGTASNQ
MSMEG_4727|M.smegmatis_MC2_155 PTGHCHAFDTAADGFVSAEGCVVLTLKRLDDAVADGDRILAVIRGTATNQ
Mflv_3391|M.gilvum_PYR-GCK PHGKCYAFDSRADGFVRGEGAGVVVLKRLTDAVRDGDRVLGVVRGSAVNQ
Mvan_3124|M.vanbaalenii_PYR-1 PHGKCFAFDSRADGFVRGEGAGVVVLKRLTDAVRDGDRVLGVVRGSAVNQ
. *:*.:* ***** .**. :: ***: ** *.**:*.*:**:* **
TH_4621|M.thermoresistible__bu DGRTENISTPSIQAQADVYRSALAVAGVDPATVGMVEAHGTGTPVGDPIE
MAV_2370|M.avium_104 DGHTVNIATPSKTAQTAVYRAALAAAGVDAGTVGMVEAHGPGTPVGDPIE
Mb1554c|M.bovis_AF2122/97 DGHTVNIATPSRSAQVAAYREALDVAGVDPATVGMVEAHGPGTPVGDPIE
Rv1527c|M.tuberculosis_H37Rv DGHTVNIATPSRSAQVAAYREALDVAGVDPATVGMVEAHGPGTPVGDPIE
MMAR_2340|M.marinum_M DGHTVNIATPSVEAQSAVYRAALATAGVDGASVGLVEAHGTGTPVGDPIE
MUL_2010|M.ulcerans_Agy99 DGRSETLLMPSETAQVAVYREALAAAGVDAASVGAVEVHGTGTPVGDPIE
MLBr_01229|M.leprae_Br4923 DGHTVHIAAPSEQAQIAVYHKALAVGGVDPTTVGLIEAHGTGTPVGDPIE
MAB_3148c|M.abscessus_ATCC_199 DGRTVNQSTPSSEAQAAACRTALAVAGVEADTVGLIEAHGTGTPVGDPIE
MSMEG_4727|M.smegmatis_MC2_155 DGRTVNIATPSADAQAKVYRMALKAAGVEPGTVGLVEAHGTGTPVGDPLE
Mflv_3391|M.gilvum_PYR-GCK DGRSNGLTAPNAPSQRDVITRALRSADVAAGTVNFVETHGTGTSLGDPIE
Mvan_3124|M.vanbaalenii_PYR-1 DGRSNGLTAPNAPSQRDVITRALRSADVAAGTVDYIETHGTGTGLGDPIE
**:: *. :* . ** ..* :*. :*.**.** :***:*
TH_4621|M.thermoresistible__bu YNSLTQVYGKTGP-CALTSVKTNFGHAESAAGALGMMKAILALQHGVVPQ
MAV_2370|M.avium_104 YASLAEVYGIDGP-CALASVKTNFGHAQAASGALGMMKAILALQHGVVPR
Mb1554c|M.bovis_AF2122/97 YASLAEVYGNDGP-CALASVKTNFGHTQSAAGALGLMKAVLALQHGVVPQ
Rv1527c|M.tuberculosis_H37Rv YASLAEVYGNDGP-CALASVKTNFGHTQSAAGALGLMKAVLALQHGVVPQ
MMAR_2340|M.marinum_M FESLARVYGIDRP-CALTSAKPNFGHMQAGAGVLGLMKAILALQHGVIPP
MUL_2010|M.ulcerans_Agy99 YRSLAQVYGSGGSRCMLGSVKTNIGHSESAAGTVGLIKATLSLGHGVVPP
MLBr_01229|M.leprae_Br4923 YASLAAVYGTAGR-CALASTKTNFGHMQSTSGPLGMMKAILALQHGVVPK
MAB_3148c|M.abscessus_ATCC_199 YTGLAQVYGVDGP-CAVGSVKTNFGHTMSAAGALGLMKIVLAVEHGVVPP
MSMEG_4727|M.smegmatis_MC2_155 FSSLAEVYGTDGP-CALGSIKTNFGHTQSAAGALGVMKAVLALQHNVIPQ
Mflv_3391|M.gilvum_PYR-GCK FDALSAVYGKGDTPCALGAVKTNMGHMEAAAGIGGFIKAVLTLQHGAIAP
Mvan_3124|M.vanbaalenii_PYR-1 FDALAAVYGKGEVPCALGAVKTNMGHLEAAAGVAGFIKTVLSLQHGKIAP
: .*: *** * : : *.*:** : :* *.:* *:: *. :.
TH_4621|M.thermoresistible__bu NLHFTRLPDEMAAIETNLFVPQATTLWP-VREGCPRRAAVSSYGMSGTNV
MAV_2370|M.avium_104 NLHFTQLPDDLARIDTKLFVPQQTTPWV-SNGGHPRRAAVSSYGLSGTNV
Mb1554c|M.bovis_AF2122/97 NLHFTALPDKLAAIETNLFVPQEITPWPGADQETPRRAAVSSYGMTGTNV
Rv1527c|M.tuberculosis_H37Rv NLHFTALPDKLAAIETNLFVPQEITPWPGADQETPRRAAVSSYGMTGTNV
MMAR_2340|M.marinum_M NIHFSRLPDEMAQIKSGLFVPQEITQWP-TNGEQTRTAAVSSYGISGTNV
MUL_2010|M.ulcerans_Agy99 MVHHTRLPDELAEIETGLYVPHEITPWP--EDQGPRRIAVSSFGMSGTNV
MLBr_01229|M.leprae_Br4923 NLHFTRLPDQLAEITTELFVPQVNTPWP-VDVQQPRRAAVSSYGMSGTNV
MAB_3148c|M.abscessus_ATCC_199 NLHFTGIPDKLAPVKTNLFVPQTVIPWP-GKAQGPRRAGVSAYGMSGSNV
MSMEG_4727|M.smegmatis_MC2_155 NLHFTRLPDQMAEIETGLFVPETITPWP-VREGQPRRAAVSAYGLSGTNV
Mflv_3391|M.gilvum_PYR-GCK NLHFQKWNPSINATGTRLFVPTEKTDWP--ETDHPRRAAVSSFGMGGTNA
Mvan_3124|M.vanbaalenii_PYR-1 NLNFEKWNPQIDPKPTRLFVPTEAQDWP--KSEHPRRAAVSSFGMGGTNA
::. .: : *:** * .* .**::*: *:*.
TH_4621|M.thermoresistible__bu HAVLEQAPEPVQRPEES----ADTDAAGPLVFALSSTSAEELRRTAGRLA
MAV_2370|M.avium_104 HAILEQAPEPAPETVAP----EGISAESPLLFPLSSTSADELRRTAGRLA
Mb1554c|M.bovis_AF2122/97 HAIVEQAPVPAPESGAPGDTPATPGIDGALLFALSASSQDALRQTAARLA
Rv1527c|M.tuberculosis_H37Rv HAIVEQAPVPAPESGAPGDTPATPGIDGALLFALSASSQDALRQTAARLA
MMAR_2340|M.marinum_M HAILEQAPETATHDAEP----VSPAIEGALIFPLSATSADGLRQTAKRLA
MUL_2010|M.ulcerans_Agy99 HAILEEPPTPAPARDQAS---AEPGMASPLLFALSSTSADGLRQTARELA
MLBr_01229|M.leprae_Br4923 HAILEQAPENSGK-DSP----AVSKVNGPLLFPLSATSVEQLRATAARMA
MAB_3148c|M.abscessus_ATCC_199 HAVVEQAPPVESSTPPA----VESPLGSQLIFPVSSTSAEELRRTAARLA
MSMEG_4727|M.smegmatis_MC2_155 HAVLEQAPESPAETAAEA---ISPKAGNALVFPVSASSADALRSTAQHLA
Mflv_3391|M.gilvum_PYR-GCK HIVLEQGPDVAAAPVDPAPK--------VATLVVSGKTPQRLAAAAASLA
Mvan_3124|M.vanbaalenii_PYR-1 HIVLEQGPEPAPAGAADTG---------VVTLVVSGKTSERLAASARSLA
* ::*: * : :*..: : * :* :*
TH_4621|M.thermoresistible__bu EWVEAHTD------EVVPADLAYTLARRRAHRPVRTTVIADGVEALTAGL
MAV_2370|M.avium_104 DWVHAHGD------LALP-DLAYTLARRRVHRPVRTAVLAGDRAQLIEAL
Mb1554c|M.bovis_AF2122/97 DWVDAQGP------ELAPADLAYTLARRRGHRPVRTAVLAATTAELTEAL
Rv1527c|M.tuberculosis_H37Rv DWVDAQGP------ELAPADLAYTLARRRGHRPVRTAVLAATTAELTEAL
MMAR_2340|M.marinum_M DWVDAQGP------ELATSDLAYTLARRRGHRPVRTAVLADNVSELSAGL
MUL_2010|M.ulcerans_Agy99 EWVGSRADSAD---STEAVDLAYTLARRRAHRPVRTAVVAASLPELVEGL
MLBr_01229|M.leprae_Br4923 DWVDEHGSGTK---HTGLWDLGYTLSRRRGYRPVRTMVLASSFAELSRGL
MAB_3148c|M.abscessus_ATCC_199 DWVAERPE-------VAPGDVGYTLARRRAHRSVRTAVVADGADELIDAL
MSMEG_4727|M.smegmatis_MC2_155 DWLLRSGDGNGRGPAIDLGDLAYTLARRRGFRAARSAVLAGDRGTLVEGL
Mflv_3391|M.gilvum_PYR-GCK DWLDGDGA------QVPLTDVAHTVNHHRSRFPTIATVCARTHAEAVAGL
Mvan_3124|M.vanbaalenii_PYR-1 DWLDGDGA------DVPLVDVAYTVNHHRSRYQTIATVCARTHAEAVTGL
:*: *:.:*: ::* . : * * .*
TH_4621|M.thermoresistible__bu REVADGDAPYQPAVGMDDKA-------PVWVFSGQGSQWAGMGAELLATE
MAV_2370|M.avium_104 REVADGDTPYPAAVGRGDRG-------PVWVFSGQGSQWAAMGADLLATE
Mb1554c|M.bovis_AF2122/97 REVATGETPYPPAVGQDDRG-------PVWVFSGQGSQWAGMGADLLATE
Rv1527c|M.tuberculosis_H37Rv REVATGEPPYPPAVGQDDRG-------PVWVFSGQGSQWAGMGADLLATE
MMAR_2340|M.marinum_M HEIADDETPYQAAVGRDDRG-------PVWVFSGQGSQWKAMGADLLANE
MUL_2010|M.ulcerans_Agy99 QEVAEGDLVYEAAVGRGDRG-------PVWVFSGQGSQWAAMGADLLANE
MLBr_01229|M.leprae_Br4923 REIAGSEIPYQSAVGQDDRG-------PVWVFSGQGSQWAGMGAELFAKE
MAB_3148c|M.abscessus_ATCC_199 RGVAEGDAPYPAAVAQDDRG-------PVWLFSGQGSQWAGMGAELLGKE
MSMEG_4727|M.smegmatis_MC2_155 RQIADGEAMPQQAVTNDDRG-------PVWVFSGQGSQWASMGAELLDRE
Mflv_3391|M.gilvum_PYR-GCK RALAAGQTAPGVVGARAAKS----GTGTVFLYSGQGAQWAGMGRTLLADE
Mvan_3124|M.vanbaalenii_PYR-1 RALADGRPAPGVIAPHDAKGGVAAGKGVVFLYSGQGAQWAGMGKTLLTSE
: :* . :. *:::****:** .** *: *
TH_4621|M.thermoresistible__bu QVFAAKIAEIEPLVARESGFSVTEAMTASETVTGIDRVQPTLFAIQVALA
MAV_2370|M.avium_104 PVFAATVAQAEPLIARESGFSVAEAMSAPQTVTGQDRVQPTLFTMQVALA
Mb1554c|M.bovis_AF2122/97 PVFAATIAAIEPLIAAESGFSVTEAMTAPEVVTGIDRVQPTLFAMQVALA
Rv1527c|M.tuberculosis_H37Rv PVFAATIAAIEPLIAAESGFSVTEAMTAPEVVTGIDRVQPTLFAMQVALA
MMAR_2340|M.marinum_M PVFAATVAELEPLIAAESGFSVTEAMTAIETVTGIDRVQPTIFTMQVALA
MUL_2010|M.ulcerans_Agy99 PVFAATVAAVEPIIAHESGFSVTEAMTAPEKVTGIDKVQPTLFAMQVALA
MLBr_01229|M.leprae_Br4923 PVFAAAIAAMEPVIVEESGFSVTEALTVAEKVTGIDRVQPTIFAIQVALA
MAB_3148c|M.abscessus_ATCC_199 PVFAETIARLEPLIHAESGFSVTDAISAPETVTGIDRVQPTLFAMQVSLA
MSMEG_4727|M.smegmatis_MC2_155 PAFAAAIAELEPLIAAESDFSVTEALTASETVTGIDRVQPTIFAVQVALA
Mflv_3391|M.gilvum_PYR-GCK PAFAAAVDELEPAFVDKVGFSLRQTLEAGEPVTGIDRIQPVLVGMQLALT
Mvan_3124|M.vanbaalenii_PYR-1 PAFAAAVDELEPAFVEKVGFSLRQTLEAGEPVVGIDRIQPVLVGMQLALT
.** : ** . : .**: ::: . : *.* *::**.:. :*::*:
TH_4621|M.thermoresistible__bu ATMQS-YGVRPGAVIGHSLGEVAAAVVAGALSLEDGVKVICRRSRLCLRL
MAV_2370|M.avium_104 ATMKA-HGVRPGAVIGHSLGEAAAAVVAGALSLEDGARVICRRSRLMSRV
Mb1554c|M.bovis_AF2122/97 ATMKS-YGVAPGAVIGHSLGESAAAVVAGALCLEDGVRVICRRSALMTRI
Rv1527c|M.tuberculosis_H37Rv ATMKS-YGVAPGAVIGHSLGESAAAVVAGALCLEDGVRVICRRSALMTRI
MMAR_2340|M.marinum_M ATMKS-YGVRPGAIIGHSLGESAAAVAAGALSLEDGAKVICRRSRLMTRI
MUL_2010|M.ulcerans_Agy99 ATMEKTYGVRPGAVIGHSLGEAAAAVVAGSLSLEDGARVISRRSKLMLRI
MLBr_01229|M.leprae_Br4923 ATMKS-YGVYPGAVIGHSLGEAAAAVAAGALSCEDGLRVICRRSQLMSRV
MAB_3148c|M.abscessus_ATCC_199 ATLAS-YGVRPGAVIGHSMGEVAAAVVSEALSLEDGVKVICRRSQLMLRI
MSMEG_4727|M.smegmatis_MC2_155 AAMRS-HGVVPGAVIGHSMGEVAASVVSGALSLEDGVKVICRRTRLMTRI
Mflv_3391|M.gilvum_PYR-GCK QLWRS-YGVEPDAVIGHSMGEATAAVVAGVLTPAEGFDIIATRTRLMKRL
Mvan_3124|M.vanbaalenii_PYR-1 ALWRS-YGVEPDAVIGHSMGEATAAVVAGVLTPAEGFDVIATRTRLMKRL
:** *.*:****:** :*:*.: * :* :*. *: * *:
TH_4621|M.thermoresistible__bu AGAGAMAAIELPAQAVREFLAARGVDDVVLSVIASPESTVIGGATDTVRE
MAV_2370|M.avium_104 AGTGATASVELPAQQVLSELTARGISDVVVAVVASPQSTVIAGAAPTVRD
Mb1554c|M.bovis_AF2122/97 AGAGAMASVELPAQQVLSELMARGVNDAVVAVVASPQSTVIGGATQTVRD
Rv1527c|M.tuberculosis_H37Rv AGAGAMASVELPAQQVLSELMARGVNDAVVAVVASPQSTVIGGATQTVRD
MMAR_2340|M.marinum_M SGSGAMASVELPAQQVLSELMARGINDVVVAVVASPQSTVIGGATDTVRE
MUL_2010|M.ulcerans_Agy99 SGAGAMASVELPAKQVNSELMARGIDDVAVAVVASPQSTVVGGATDTVRD
MLBr_01229|M.leprae_Br4923 AGSGAMASVELPGQQVLSELSIRGLSDVVLAVVASPTSTVVGGDTQAIRH
MAB_3148c|M.abscessus_ATCC_199 SGAGAMASVDLPAQQVVSELADRDIHDVVLAVVASPQSTVVGGATETVRQ
MSMEG_4727|M.smegmatis_MC2_155 AGSGAMAMVELPAQQVLSELASRGVDDVVLSVVASPQSTVVGGATASVRE
Mflv_3391|M.gilvum_PYR-GCK SGQGAMALLELDAQATEKLIADR--PDITIAVYASPKQCVIAGPPEQVDE
Mvan_3124|M.vanbaalenii_PYR-1 SGQGAMALLELDAQATEKLIADR--SDVTIAVYASPKQTVIAGPPEQVDE
:* ** * ::* .: . . : * * .::* *** . *:.* . : .
TH_4621|M.thermoresistible__bu LVAAWEAQGVMAREVAVDVASHSPQVDPILDELEEILADLQPMTPTVPYY
MAV_2370|M.avium_104 LVTAWQERGVMAREVPTDVAFHSPQVDPIMDDLTDALAEISPRPPEVPYY
Mb1554c|M.bovis_AF2122/97 LVAAWEQRDVLAREVAVDVASHSPQVDPILDELAEALAEISPLQPEIPYY
Rv1527c|M.tuberculosis_H37Rv LVAAWEQRDVLAREVAVDVASHSPQVDPILDELAEALAEISPLQPEIPYY
MMAR_2340|M.marinum_M LVAAWEQREVMAREVAVDVASHSPQVDPILDDLYDVLADLEPLTPEVPYY
MUL_2010|M.ulcerans_Agy99 LVARWEQREVMAREVAVDVASHSPQVDPILEDLATALADIVPSDPKVPYY
MLBr_01229|M.leprae_Br4923 LLAAWQAQDVMVREVAVDVASHTPQVEPILDDLVETLADLKPTEPKVPYY
MAB_3148c|M.abscessus_ATCC_199 LIAEWSDRGLMAREVAVDVASHSPQVDPILDDLADALEDLTPRTPVVPLY
MSMEG_4727|M.smegmatis_MC2_155 LIEMWESRGVMAREIAVDVASHSPQVDPILDDLIEALADLDPAEPEIPYY
Mflv_3391|M.gilvum_PYR-GCK LVALVDAQGKLARRVEVDVASHHPTIDPVLGELRDALSYLSPAAPKIPLV
Mvan_3124|M.vanbaalenii_PYR-1 LVAAVDAQGKLARRIEVDVASHHPTIDPVLPELREALAYLTPAAPKIPLV
*: . : :.*.: .*** * * ::*:: :* * : * * :*
TH_4621|M.thermoresistible__bu SATSYDPREKPVCDADYWVDNLRHEVRFAAAVQAALEDGFRVFGELSPHP
MAV_2370|M.avium_104 SATLFDPREQPVCDARYWANNMRRMVRFATAVQAALEDGYRVFAELAPHP
Mb1554c|M.bovis_AF2122/97 SATSFDPREEPYCDAYYWVDNLRHTVRFAAAVQAALEDGYRVFTELTPHP
Rv1527c|M.tuberculosis_H37Rv SATSFDPREEPYCDAYYWVDNLRHTVRFAAAVQAALEDGYRVFTELTPHP
MMAR_2340|M.marinum_M SATLFDPREEPYCDGSYWVDNLRHTVRFGAAVQAALEDGYRVFAELAPHP
MUL_2010|M.ulcerans_Agy99 SATLFDPRERPTCDAAYWVDNLRNTVQFAAAVQAALEDGFRVFAELSPHP
MLBr_01229|M.leprae_Br4923 SATLWDPRERPSFTGEYWAENLRYTVRFAAAVQAALKDGFRVFGELAPHP
MAB_3148c|M.abscessus_ATCC_199 SSVSFDPRERPIMDADYWVDNLRHTVRFAAAVQAALDDGYRVFGELAPHP
MSMEG_4727|M.smegmatis_MC2_155 SATLYDPRDYADYDAYYWADNLRHTVRFSAAVQAALEDGHRVFAELSPHP
Mflv_3391|M.gilvum_PYR-GCK STVAYAG-SAPLYSADYWAANLRNPVRFSQAVHEAAAD-HSNFVEISPHP
Mvan_3124|M.vanbaalenii_PYR-1 STVGYAG-DAPMYSADYWAANLRNPVRFSQAVHDASAE-NSNFIEISPHP
*:. : . . . **. *:* *:*. **: * : * *::***
TH_4621|M.thermoresistible__bu LLTRAVEQTARGLDMPVAALPAMRREQEMPHGVRTMVGDLFAAGAAVDFA
MAV_2370|M.avium_104 LLVRALEQTARSREIPMAALAGMRRGQALPHGLRGFVADLHNAGAAVDFS
Mb1554c|M.bovis_AF2122/97 LLTHAVDQTARSLDMSAAALAGMRREQPLPHGLRALAGDLYAAGAAVDFA
Rv1527c|M.tuberculosis_H37Rv LLTHAVDQTARSLDMSAAALAGMRREQPLPHGLRALAGDLYAAGAAVDFA
MMAR_2340|M.marinum_M LLTRAVEKTAEGLDMPVAALAGMRREQPLPHGLRGLLADLHSAGAAVDFS
MUL_2010|M.ulcerans_Agy99 LLTHAVDQNARSLDMSAAVLAGMRREQPLPHGLRGLLTDVHSAGAAVDFS
MLBr_01229|M.leprae_Br4923 LLTYAIEQNAASLDMPVSALAAMRREQELPFGLRGFIADVHSAGALVDFS
MAB_3148c|M.abscessus_ATCC_199 LLVYPAEQTARSLDIPMVALAGMRREQELPHGLRDFVGDLYTAGGAVDFS
MSMEG_4727|M.smegmatis_MC2_155 LLTHPVEQTARSLDMPLAVFAAMRRQQEMPHGLLGFVADLHSAGAAVDFS
Mflv_3391|M.gilvum_PYR-GCK LLTHAISDTLAAQSTSRKFHVGATLNRDHPE-PLAFHAQLSALRPPAVTA
Mvan_3124|M.vanbaalenii_PYR-1 LLTHAISDTLAAQSTSRRYHVGATVNRDNPE-PLAFHAQLAAVRPPAVQA
**. . ... . . . . : * : :: . :
TH_4621|M.thermoresistible__bu ALYPSGRLVDAPLPTWTRRKLVLSRENGEQQTRGGCTITVHPLLGTHVRL
MAV_2370|M.avium_104 VLYPTGRLVDAPLPTWTHRRLWLTDGGLESPTHGGCTVAVHPLLGPHVHL
Mb1554c|M.bovis_AF2122/97 VLYPTGRLINAPLPTWNHRRLLLDDT--TRRIAHANTVAVHPLLGSHVRL
Rv1527c|M.tuberculosis_H37Rv VLYPTGRLINAPLPTWNHRRLLLDDT--TRRIAHANTVAVHPLLGSHVRL
MMAR_2340|M.marinum_M VLYPAGELVDAPLPAWTHQSLLLNRAGQDHQAQGGSSVVVHPLLGSHVLL
MUL_2010|M.ulcerans_Agy99 VLYPAGRLVNAPPPAWTHRRFFVDGEGQDSKAQGACSVTVHPLLGAHVRL
MLBr_01229|M.leprae_Br4923 VQYPNGCLVDAPLPTWTRRELMLSRESVDHPAHGAAVQAVHPLLGAHVHL
MAB_3148c|M.abscessus_ATCC_199 VLYPTGQLVDVPLPSWTRRSYLLDLSAQAQQGHGTHTVAVHPLLGAHVRL
MSMEG_4727|M.smegmatis_MC2_155 VLYPTGRLLDAPLPAWTHSTLLLDRELESSAP-GVPSVSVHPLLGSHVVL
Mflv_3391|M.gilvum_PYR-GCK PDGATGRVVDVPATAWQHTPYWMADR-----SGGPQFAGAHPLLGLHVEL
Mvan_3124|M.vanbaalenii_PYR-1 PEGTPGRLADIPPTAWQHSPYWMVDR-----SAGQGFSGAHPLLGLHVEL
. * : : * .:* : : .***** ** *
TH_4621|M.thermoresistible__bu PEEPERHVWQADLGTGAQPWLADHQIHTVAALPGAAYCEMALAAAREVID
MAV_2370|M.avium_104 QEEPERHLWQADVGTAAQPWLADHQIRNVVVLPGAAYCEMALAAARSVLG
Mb1554c|M.bovis_AF2122/97 PEEPERHVWQGEVGTVTQPWLADHQIHGAAALPGAAYCEMALAAARAVLG
Rv1527c|M.tuberculosis_H37Rv PEEPERHVWQGEVGTVTQPWLADHQIHGAAALPGAAYCEMALAAARAVLG
MMAR_2340|M.marinum_M PEEPERHVWQSDVGTEALPWLADHQIHSAPALPGAAYCEMALVAARTILG
MUL_2010|M.ulcerans_Agy99 SEQPERHVWQTDVGTDTLSWLSDHQVRNVAALPGAAYCEMALAAAGEVFG
MLBr_01229|M.leprae_Br4923 FEEPERHVWQGRVGTEAHPWLGDHQIHDVAAFPGAAYCEMALTAARVTLG
MAB_3148c|M.abscessus_ATCC_199 AEEPERHIWQADVGTVGQPWIADHQVRHVAVYPGAAYCEMALSAAAAVFG
MSMEG_4727|M.smegmatis_MC2_155 PQEPEEHLWQGDVGTEAHPWLSDHRVHQVAVLPGAAYCEMALAAVTPVLG
Mflv_3391|M.gilvum_PYR-GCK PAGAG-HVWQSDVGLEAHPWLADHIVHGLPVMPGAGFAEIALAAAQEALG
Mvan_3124|M.vanbaalenii_PYR-1 PSGTG-HVWQSDVGVQAHPWLADHIVHGLAVMPGAGFAEIALAAGREALG
. *:** :* .*:.** :: . ***.:.*:** * :.
TH_4621|M.thermoresistible__bu SDG-VEVRDVRFEQMLLLDEQTEVSAVASAVEPGTLEFAVETAK-DGEHE
MAV_2370|M.avium_104 AT--AEVRDIRFEQALLLDEQTTVDASASVSSPGVLHFTVQSHQ-GGEQA
Mb1554c|M.bovis_AF2122/97 EA--SEVRDIRFEQMLLLDDETPIGVTATVEAPGVVPLTVETSH-DGRYT
Rv1527c|M.tuberculosis_H37Rv EA--SEVRDIRFEQMLLLDDETPIGVTATVEAPGVVPLTVETSH-DGRYT
MMAR_2340|M.marinum_M DA--AEVRDVRFEQMLLLDDETPLSAVGSVKSPGIVDFVVETFQ-DGGAV
MUL_2010|M.ulcerans_Agy99 EA--FEVRDLAFEQMLLLDEETPIDAVASLDSPGAANFVVQTHV-DGETT
MLBr_01229|M.leprae_Br4923 EA--SEVRDIKFEQTLLLDRETMASSAATVSAPGVLEFAVETYE-EGERV
MAB_3148c|M.abscessus_ATCC_199 EG--SAVQSISFEQLLTLGESTPISATATAKSADILEFVVETHD-EGDVV
MSMEG_4727|M.smegmatis_MC2_155 DT--GEVHDLKFHDMLLLDDATPVWVSAAVTAPGTAEFGVETHQ-SGDRT
Mflv_3391|M.gilvum_PYR-GCK LPATGVEVALEVQEMLLLDAHTTLTTQVSTAEDGTLRVEIHSRSEAGTWT
Mvan_3124|M.vanbaalenii_PYR-1 LPATGVEVQLEVEQMLPLDDHTKLTTQLTRDDEENLRVEIHSRSDAGSWT
: ..: * *. * : . :.: *
TH_4621|M.thermoresistible__bu RRATAVLGAADDTE----PPQAHDIDALLAEHPTRIEGDELRQWFDQRGV
MAV_2370|M.avium_104 RHASAVLGAATD-E----QPAAHDLSALLTAHPHDDDGDEVRRRMDRRGV
Mb1554c|M.bovis_AF2122/97 RQLAAVLHVVREADDAPDQPPQKNIAELLASHPHKVDGAEVRQWLDKRGH
Rv1527c|M.tuberculosis_H37Rv RQLAAVLHVVREADDAPDQPPQKNIAELLASHPHKVDGAEVRQWLDKRGH
MMAR_2340|M.marinum_M RRGGAVLHAVEDDD----QLPAYDIPALLAEHSRTEDGEELRARFDEHGV
MUL_2010|M.ulcerans_Agy99 RHATAALRASDDES----VPPAYDIAALLAAHPVSVNGAELREAFVERGI
MLBr_01229|M.leprae_Br4923 RRASAVLRALEDRVN--QQPASHSIDALIASHPLRTEGADLRATFDAIGI
MAB_3148c|M.abscessus_ATCC_199 KRATAVLGNGGDVD----MPIAYDLSALRAEHPHRESGDDLRASFDERGV
MSMEG_4727|M.smegmatis_MC2_155 QRATAVLRGDVDAER----PAAHSIDALLAAHPNRVDGDELRAGFGTVGI
Mflv_3391|M.gilvum_PYR-GCK RHAAGSVRAAAGATP---------PRPAPLSEGTPVSPADFYTALRRTGA
Mvan_3124|M.vanbaalenii_PYR-1 RHAVGTVKAAAGPAP---------AKVVPASDGTPVSPSDFYTALRRTGA
:: . : . . :. : *
TH_4621|M.thermoresistible__bu QFGPAFTGLTAARIPEG---TVTSVLAEVGLPGQIRSQQAPYGIHPALLD
MAV_2370|M.avium_104 QYGPAFAGLGAVHSGDE---TGT-VLAEVALPRQIRSQQAAYGAHPALLD
Mb1554c|M.bovis_AF2122/97 RLGPAFAGLVDAYIAEG---AGDTVLAEVNLPGPLRSQVKAYGVHPVLLD
Rv1527c|M.tuberculosis_H37Rv RLGPAFAGLVDAYIAEG---AGDTVLAEVNLPGPLRSQVKAYGVHPVLLD
MMAR_2340|M.marinum_M QYGPAFTGLGNAHIADG---AVSSVVAEVALPGAMRSQQRAYAIHPALLD
MUL_2010|M.ulcerans_Agy99 QHGPAFSGLAIARTAET---EGGTVLAEVALPASIRFQQGAYGVHPALLD
MLBr_01229|M.leprae_Br4923 QYGLAFSGLTAVYTAAGTNEDVSTVLAEVALPGAIRSQQASYTSHPALLD
MAB_3148c|M.abscessus_ATCC_199 QYGPAFQGLAAAYRGDE---TVRSVLAEVTLPRDVRAQQGSYIVHPALLD
MSMEG_4727|M.smegmatis_MC2_155 GHGAAFAGLSEAYVATA---AEPTVVAAVALPGPLRSGQRGYTVHPALLD
Mflv_3391|M.gilvum_PYR-GCK HHAHAFAALTRIVRAAG------TADTEIVLPDEATPHRG-VALHPVMLD
Mvan_3124|M.vanbaalenii_PYR-1 HHAHAFAALTRIVRAGG------RADTEIVLPDEATPHRG-IALHPVMLD
. ** .* . : : ** **.:**
TH_4621|M.thermoresistible__bu ACFQSVAAHP--DVQGAGSGLL-LPLGVRRLQAFGPTRGARYCYARVTDA
MAV_2370|M.avium_104 ACFQSVEAHP--AVRALGDGALGLVLGIRRLRAYGAARNAHYCYTRVTKA
Mb1554c|M.bovis_AF2122/97 ACFQSVAAHP--AVQGMADGGLLLPLGVRRLRSYGSARHARYCCTTVTAC
Rv1527c|M.tuberculosis_H37Rv ACFQSVAAHP--AVQGMADGGLLLPLGVRRLRSYGSARHARYCCTTVTAC
MMAR_2340|M.marinum_M ACFQAVGAHP--DVQVAGNGGLMLPLGVRQIRAYASTRNAHYCYARVTSV
MUL_2010|M.ulcerans_Agy99 ACFQSVAAG----VKSTGGGGLLLPLGVRSLRAYGPTRNAQYCYTRVTKA
MLBr_01229|M.leprae_Br4923 ACFQSVIVAP--EVQKAGAGGLLLPVYVRRLLNYHSMRNAQYCLTRVKTS
MAB_3148c|M.abscessus_ATCC_199 ACFQSVIALP--DVQEASKDALPLPKGVRSLHAYESARATQYCYTRVTKV
MSMEG_4727|M.smegmatis_MC2_155 ACFQSVIAHP--EVQNIA-SGMLLPLGVRRLRAYGSTRNVRYCLSRIVKA
Mflv_3391|M.gilvum_PYR-GCK AALQGLAAALGDDSLTDSNDVTYLPVGFGSVRVFAEVGRRAKCRAELLSV
Mvan_3124|M.vanbaalenii_PYR-1 AALQGLAAAMSDETLSDSTDVTYLPVGFGSIRVFGDIGRRAKCRAELVSV
*.:*.: . . . * . : : * : :
TH_4621|M.thermoresistible__bu DG-------SKAEADLDVLDEHGNVLLRVQGLLMGGAAADGDDRDRVLGE
MAV_2370|M.avium_104 DT-------SGVEADIDVLDEHGAVLLAVQGLRVGTSASESGTRDRVLTE
Mb1554c|M.bovis_AF2122/97 G--------VGVEADLDVLDEHGAVVLAVRGLQLGTGASQASERARVLGE
Rv1527c|M.tuberculosis_H37Rv G--------VGVEADLDVLDEHGAVVLAVRGLQLGTGASQASERARVLGE
MMAR_2340|M.marinum_M DT-------SAVEADLDVLDEHGTVLVAVRGLQLGTGVSEEGNRDRVLNE
MUL_2010|M.ulcerans_Agy99 DA-------NGGEADLELLDEQGCVLLAVRGLRLGTGTSESGERDRVLSE
MLBr_01229|M.leprae_Br4923 RA-------GECEVDLEVLDQSGAVLLLVEGLRLAGGASEHECANRVLDE
MAB_3148c|M.abscessus_ATCC_199 VG-------NEVEADIDLLDETGSVLIAVRGFRFGTGSSDDEQRDQLLNN
MSMEG_4727|M.smegmatis_MC2_155 DS-------FGVEADLELLDADGTVLLSAMGLQLGTGNSDKAEEERLLDE
Mflv_3391|M.gilvum_PYR-GCK ASGVDGQGSGDAVGRVTLTDDTGTVLAQVDDVALKR--IQRRTVPLPLSQ
Mvan_3124|M.vanbaalenii_PYR-1 VE-----DSGDAMGRVTLTDDTGTVLAQVDDVHLKR--VQRRTVPLPLSQ
: : * * *: . .. . : * :
TH_4621|M.thermoresistible__bu RLLTIEWQRRDLPE---ADSA-AGKWLLVSTSA-TADVSATRLSDALKQA
MAV_2370|M.avium_104 RLLNIEWRQRELPE---PEHADAASWLLIGTTA-TADVLASTLADTLKNH
Mb1554c|M.bovis_AF2122/97 RLLSIEWHERELPE---NSHAEPGAWLLISTCD-ATDLVAAQLTDALKVH
Rv1527c|M.tuberculosis_H37Rv RLLSIEWHERELPE---NSHAEPGAWLLISTCD-ATDLVAAQLTDALKVH
MMAR_2340|M.marinum_M RLLTIEWQQRELPE---VDAAEAGAWLLISTSD-GADMLAAELTDALKLH
MUL_2010|M.ulcerans_Agy99 RLLTLEWQQRQLPE---VLDEETGSWLLISASD-GEDLMATTLADALKSQ
MLBr_01229|M.leprae_Br4923 RLFTVEWEPRELPE---VTQRERGSWLVLGAS--AEDPLVQQLGDALNAD
MAB_3148c|M.abscessus_ATCC_199 RLLAIEWQQQRLPE---SVSGAPRRWLLVSTGE-SVDPWAAELIDSLKVR
MSMEG_4727|M.smegmatis_MC2_155 RLLTIEWQQRELPRPEGSETVDAGSWLVILAGDDDENPRAAGVVSALIGA
Mflv_3391|M.gilvum_PYR-GCK KIFDSRWVPAQATAG----AAQAGSWLVLADGD-HTLASAERFAQSFGDA
Mvan_3124|M.vanbaalenii_PYR-1 KIFDSRWVESAAAAG----TTATGSWLALADGA-AGQAAAQDFASRFGAD
::: .* . ** : . . . :
TH_4621|M.thermoresistible__bu GAESTSMCWPQ-QADHADNVDRFR-AGIAD--------GVTGVVVLTGPK
MAV_2370|M.avium_104 GAQCTTMAWPQ-QADHTAHAEQLRNQWRGD--------GFTGVVVLTGPK
Mb1554c|M.bovis_AF2122/97 DAQCTTMSWPQ-RADHAAQAARLRDQLGTG--------GFTGVFVLTAPQ
Rv1527c|M.tuberculosis_H37Rv DAQCTTMSWPQ-RADHAAQAARLRDQLGTG--------GFTGVFVLTAPQ
MMAR_2340|M.marinum_M SAQCATTSWHENAADHAASAERLRNQLNAG--------GFHNAVILLKPD
MUL_2010|M.ulcerans_Agy99 GAECASMVWSA-QDDLAGGIEKLGAQLRAR--------TNKGVVIVCGPR
MLBr_01229|M.leprae_Br4923 GGHCTAVSLPLGQIDTAQLCSLLSRDGVSSSIGHGALKGLTGVVVVTAPP
MAB_3148c|M.abscessus_ATCC_199 ESEVSLIQWRP-NTDRVAALKLLYDQLESG--------TFDGVLVVTAPG
MSMEG_4727|M.smegmatis_MC2_155 GMPTTTMAWSH-DADHDAQAAALTARLDEQ--------PLAGVAVIVGDS
Mflv_3391|M.gilvum_PYR-GCK QHRVVTARLGDEAAVRDAFASATTDAALPP----------AGVVVLVDVP
Mvan_3124|M.vanbaalenii_PYR-1 TRRVITADLGDESAVREAFATATADPDLPP----------VGVVVFCDFG
.. :.
TH_4621|M.thermoresistible__bu N--GNPDDAAA----RRGSDYVRHLVRITRELA-EIDGDAPRLFVVTRGA
MAV_2370|M.avium_104 N--GDNDQESA----LLSRDHVQHLVRIARELT-DLPGEPPRLYVVTRNA
Mb1554c|M.bovis_AF2122/97 T--GDPDAESP----VRGGELVKHVVRIAREIP-EITAQEPRLYVLTHNA
Rv1527c|M.tuberculosis_H37Rv T--GDPDAESP----VRGGELVKHVVRIAREIP-EITAQEPRLYVLTHNA
MMAR_2340|M.marinum_M S--GDRDENSG----VEGVECVRHVVRVVRELP-EIMGEAPRLFVVTRGA
MUL_2010|M.ulcerans_Agy99 S--GDADEQSL----LQGREQVRHLVRITRGLA-ELEGELPRLFVVTRQA
MLBr_01229|M.leprae_Br4923 A--TVAESPAL----RRGRDYVSHLITIVREIS-ELPGERPRLFVVTRNA
MAB_3148c|M.abscessus_ATCC_199 S--EGGADRVV----LQGADQVRHLVRITRELV-DLPGEPPRLFVVTRNA
MSMEG_4727|M.smegmatis_MC2_155 E--TGTDAHDVGADARRGADHVRHLVRIARTLA-DAVGEPPRLYVVTHRS
Mflv_3391|M.gilvum_PYR-GCK ----AFDGADAAGGLAAAQNAVWEIAETVRTIVGSWHGTPPRLWVVSRGG
Mvan_3124|M.vanbaalenii_PYR-1 GNPATLDGTDVAGGLEHARDVIWGVAGTVRAIVGSWHGKAPRLWLVTQGG
. : : : .* : . . ***::::: .
TH_4621|M.thermoresistible__bu QAVLPQD-RPNLEQAGLRGLLRVIGAEHPHLRTTQIDIADDADL---DRV
MAV_2370|M.avium_104 QTVLPND-VPNLGQAGLRGLVRVIGMEHPQLGAGQIDVDESTDA---QAL
Mb1554c|M.bovis_AF2122/97 QAVLSGD-RPNLEQGGMRGLLRVIGAEHPHLKASYVDVDEQTGA---ESV
Rv1527c|M.tuberculosis_H37Rv QAVLSGD-RPNLEQGGMRGLLRVIGAEHPHLKASYVDVDEQTGA---ESV
MMAR_2340|M.marinum_M QTVLGGE-SANLEQAGLRGLLRVIGAEYPHLHTTHVDVDEHSGS---EVV
MUL_2010|M.ulcerans_Agy99 QRVRPED-EINLEQAGLRGLLRVIGSEHPLLQTTQVDVDESTQA---EQL
MLBr_01229|M.leprae_Br4923 ASIKTGD-LANLEQVGLRGLIRVIDSEHPYLSVTQIDVEETNQATIATQV
MAB_3148c|M.abscessus_ATCC_199 QTVVDGD-ITNLEQAGLRGLVRVIGAEYPHLRVTHIDVDRHTAA---QNV
MSMEG_4727|M.smegmatis_MC2_155 QHVLDTD-EPYLEHSGLRGLIRVVGMEHPRLRATQIDVDDSTAH---EAL
Mflv_3391|M.gilvum_PYR-GCK LAVTDGDNGGNPGVGTLKALIRVLAYEHPDLRATLLDVGADGDT--AAIL
Mvan_3124|M.vanbaalenii_PYR-1 LVVSPEDGQGNPGANSLKGLARVLAYEHPDLKTTLLDTGSDG-----AAL
: : ::.* **: *:* * . :* :
TH_4621|M.thermoresistible__bu AVQLLGGGA----EDETAWRDGQWYTARLSLSPLRPEERKQAVVDCERDG
MAV_2370|M.avium_104 ARQLLAGSE----EDETAWRDGAWYTARLCPAPLLPEERHTAVANHECDG
Mb1554c|M.bovis_AF2122/97 ARQLLAASG----EDETAWRNDQWYTARLCPAPLRPEERQTTVVDHAEAG
Rv1527c|M.tuberculosis_H37Rv ARQLLAASG----EDETAWRNDQWYTARLCPAPLRPEERQTTVVDHAEAG
MMAR_2340|M.marinum_M ARQLLSGSE----EDETAWRCGQWYTARLSPMPLRPEERKTTVVEHDTEG
MUL_2010|M.ulcerans_Agy99 AQQLLGGSE----EDETAWRGGEWYVARLFPGPLSADERQTTVVDHERDN
MLBr_01229|M.leprae_Br4923 ARQLRSGSD----EDETGWRDGEWYTARLRPGPLRQAERRTVVVQNEHDG
MAB_3148c|M.abscessus_ATCC_199 AGELVSGSE----EDETAWREDHWYRARLNLGPLGPDDWRSTVATPNNEG
MSMEG_4727|M.smegmatis_MC2_155 VRQLLSGSP----EDETAWRDGQWYAARLCPSPLRAAERRTAVADNASEG
Mflv_3391|M.gilvum_PYR-GCK ATEIGSANDSTTTEDTIAWRDGSRLVERLSRAELP---------------
Mvan_3124|M.vanbaalenii_PYR-1 ATEIEAASASAVTEDVIAWRGGTRYVERLSRATLP---------------
. :: ... ** .** . ** *
TH_4621|M.thermoresistible__bu MRLEIRTPGDLETMELAAFDRVPPGPGQIEVAVTASSINFADVLIAFGRY
MAV_2370|M.avium_104 MRLQIRTPGDLESLELVACDRIPPGPGQIEVAVSASSINFADVLVAFGRY
Mb1554c|M.bovis_AF2122/97 MRLQIRTPGDLQTLEFAALDRVPPGPGEIEVAVTASSINFADVLVTFGRY
Rv1527c|M.tuberculosis_H37Rv MRLQIRTPGDLQTLEFAAFDRVPPGPGEIEVAVTASSINFADVLVTFGRY
MMAR_2340|M.marinum_M MRLQIRTPGDLQTMEFVAFDRVAPGPGQIEVAVSTSSINFADVLVSFGRY
MUL_2010|M.ulcerans_Agy99 MRLQIRTPGDLQTLELAACDRVPPGPGQIEVAVTMSSINFADVLIAFGRY
MLBr_01229|M.leprae_Br4923 MRLEIRTPGDLDSLEFVAFDRVPPGPGEIEVAVTASTVNFADVLVAFGRY
MAB_3148c|M.abscessus_ATCC_199 VRFEVRTPGDLQSLGFVAFDRVAPGPGQIEVSVTATSINFADVLNVYGRY
MSMEG_4727|M.smegmatis_MC2_155 MRLVVRNPGDLESMELVTFERGTPGPGQIEVAVKASSINFADVLVAFGRC
Mflv_3391|M.gilvum_PYR-GCK -----AVPGRLQ--------------------------------------
Mvan_3124|M.vanbaalenii_PYR-1 -----ATPGQLV--------------------------------------
** *
TH_4621|M.thermoresistible__bu PTFDGRRPQLGTDFAGVVTAVGPDVTSHRVGDRVGGLSPNGCWSTFVTCD
MAV_2370|M.avium_104 PAFEGRLPELGTDFAGVVTAVGPDVTDHKVGDHVGGLSANGCWGTFLTCD
Mb1554c|M.bovis_AF2122/97 QTLDGRQPQLGTDFAGVVSAVGPGVSELKVGDRVGGMSPNGCWATFVTCD
Rv1527c|M.tuberculosis_H37Rv QTLDGRQPQLGTDFAGVVSAVGPGVSELKVGDRVGGMSPNGCWATFVTCD
MMAR_2340|M.marinum_M NSPDGQMPQLGTDFAGVVTAVGPDVTDHQVGDRVGGMSPHGCWATFVTCD
MUL_2010|M.ulcerans_Agy99 PSLEGRLPETGTDFVGVVTAVGEGVTDHQVGDRVGGFSKDGCWRSYLTCD
MLBr_01229|M.leprae_Br4923 PTFEGYCQLLGIDFAGVVSAVGLNVTDHKVGDRVGGVSRNGCWTTFVICD
MAB_3148c|M.abscessus_ATCC_199 SSFEGR-QELGVDFAGVVTAVGEGVTQHQVGDRVGGMTPTGAWRSFVVVD
MSMEG_4727|M.smegmatis_MC2_155 PSFDGRLPELGSEFGGVVTAVGPGVTTHRVGDRVGGVSANGCWSNFVTCE
Mflv_3391|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3124|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4621|M.thermoresistible__bu ADLAVPLPDGLTEGQAAAVSTAHATAWYGLHDLARLGAGEKVLIHSATGG
MAV_2370|M.avium_104 ARLAVTLPPGLADDQAAAVTTAHATAYYGLHELARIGAGDRVLIHSATGG
Mb1554c|M.bovis_AF2122/97 ARLATRLPEGLTDAQAAAVTTASATAWYGLQDLARIKAGDKVLIHSATGG
Rv1527c|M.tuberculosis_H37Rv ARLATRLPEGLTDAQAAAVTTASATAWYGLQDLARIKAGDKVLIHSATGG
MMAR_2340|M.marinum_M GALATPIPAGLTDAQAAAVTTAHATAWYGLHDLGRIRAGDKVLIHSGTGG
MUL_2010|M.ulcerans_Agy99 ANLAVTLPAGLSDEHAAASSTAHATAWYGLNDLAGIKAGDRVLIHSATGG
MLBr_01229|M.leprae_Br4923 ARHAVTLSPEVPLEEAAAVPTVAATAWYGLHDLARISQTDKVLIHSGTGG
MAB_3148c|M.abscessus_ATCC_199 ANLAATLPAEVPDREAAAVPGAHVTAWYGLHELARISAGDKVLIHSGTGG
MSMEG_4727|M.smegmatis_MC2_155 ADLATKLPEGISEHEAAAVGLAYGTVWLGLTELARMSAGDKILIHSATGG
Mflv_3391|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3124|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4621|M.thermoresistible__bu VGLAAIAIARSVGAQIYATAGSPARRDLLRDMGIEHVYDSRSTAFADEIR
MAV_2370|M.avium_104 VGQAAIAIARAAGAEIFATAGSEQRRQLLRDMGIEHVYDSRTVEFADLIR
Mb1554c|M.bovis_AF2122/97 VGQAAIAIARAAGAQIYATAGNEKRRDLLRDMGIEHVYDSRSVEFAEQIR
Rv1527c|M.tuberculosis_H37Rv VGQAAIAIARAAGAQIYATAGNEKRRDLLRDMGIEHVYDSRSVEFAEQIR
MMAR_2340|M.marinum_M VGQAAIAIARAAGAEIYATAGSPKRRQVLRDMGIEHVYDSRSIEFAEAIR
MUL_2010|M.ulcerans_Agy99 VGQAAIAIARAAGAQIFATAGNAERRQLVNDMGIEHVYDSRSIEFADQIR
MLBr_01229|M.leprae_Br4923 VGQAAIAIARAAGCEIFATAGSPQRRQLLRDKGIEHVYDSRSLEFAEQIH
MAB_3148c|M.abscessus_ATCC_199 VGQAAIAIARAAGAEIYATAGSPERRDLLRSWGIKHVYDSRSTDFAELIR
MSMEG_4727|M.smegmatis_MC2_155 VGQAAIAVARAAGAEIYATAGSEKRRQLLRDWGIEHVYDSRTTAFADQIR
Mflv_3391|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3124|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4621|M.thermoresistible__bu RDTDGYGVDVVLNSLPGAAQRAGLELLSFGGRFIEIGKRDIYGDTRLGLF
MAV_2370|M.avium_104 HDTDGYGVDIVLNSVTGAAQRAGIELLAFGGRFVEIGKRDIYGDTRLGLL
Mb1554c|M.bovis_AF2122/97 RDTAGYGVDIVLNSVTGAAQLAGLKLLALGGRFIEIGKRDIYSNTRLELL
Rv1527c|M.tuberculosis_H37Rv RDTAGYGVDIVLNSVTGAAQLAGLKLLALGGRFIEIGKRDIYSNTRLELL
MMAR_2340|M.marinum_M ADTDGYGVDIVLNSLTGAAQRAGLELLAWGGRFVEIGKRDIYGDTKMGLF
MUL_2010|M.ulcerans_Agy99 RDTNGYGVDIVLNSLTGAAQRAGLELLAFGGRFVEIGKADVYGNTRMGLY
MLBr_01229|M.leprae_Br4923 RDTKGYGVDVVLNSLPGAAQRAGIELLAFGGRFVEIGKRDIYGDTRLGLF
MAB_3148c|M.abscessus_ATCC_199 RDTDGYGVDIVLNSLTGAAQRAGVELLTFGGRFIEIGKRDIYGDTRLGLF
MSMEG_4727|M.smegmatis_MC2_155 TDTDGYGVDIVLNSVTGPAQRAGLELLAFGGRFVEIGKRDIYADTRLGLF
Mflv_3391|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3124|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4621|M.thermoresistible__bu PFRRNLAFHGVDLGLMADSHPHKIRELLETVYRLTADGVLPMPQSTHYPL
MAV_2370|M.avium_104 PFRRNLTFYALDLALMSFSHPDRLRGLLRTVYRLTADGALPMPESTHYPL
Mb1554c|M.bovis_AF2122/97 PFRRNLAFYGLDLGLMSVSHPAAVRELLSTVYRLTVEGVLPMPQSTHYPL
Rv1527c|M.tuberculosis_H37Rv PFRRNLAFYGLDLGLMSVSHPAAVRELLSTVYRLTVEGVLPMPQSTHYPL
MMAR_2340|M.marinum_M PFRRNLSFYGVDLGMLSITHPRLIRELLTTVYQHTAEGVLPMPQDTHYPL
MUL_2010|M.ulcerans_Agy99 PFRRGLTFYYVDLGLMSVIQPERVRELLSTVYNLTAEGVLSAPECTHYPL
MLBr_01229|M.leprae_Br4923 PFRRNLSLYAVDLALLTYTHPDTVRRLLTTVYQRTAEGVLPVPQTTHYPI
MAB_3148c|M.abscessus_ATCC_199 PFRRNLSFHAVDLVLVAKTRPEAIYRTLTALYGQMAEGVLPLPEISPSPL
MSMEG_4727|M.smegmatis_MC2_155 PFRRNLSFYAVDLALMTVTHPQKIRDLLATVYRLIADGTLPLPEITHYPL
Mflv_3391|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3124|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4621|M.thermoresistible__bu AEAATAIRVMSAAEHVGKLVLDVPHTGRADVVVPPEQASPFRSDGAYIVT
MAV_2370|M.avium_104 ADAASAIRVMSAAQHTGKLVLDVPHAGRSRVVVPPAQVRAFRSDGAYIVT
Mb1554c|M.bovis_AF2122/97 AEAATAIRVMGAAEHTGKLILDVPHAGRSSVVLPPEQARVFRSDGSYIIT
Rv1527c|M.tuberculosis_H37Rv AEAATAIRVMGAAEHTGKLILDVPHAGRSSVVLPPEQARVFRSDGSYIIT
MMAR_2340|M.marinum_M AEAATAIRVMGAADHTGKLLLDIPRSGRSAVVLPPEQVPVLRADGSYIIT
MUL_2010|M.ulcerans_Agy99 AEAAEAIRTMSNAAHTGKLLLDMPRSGRRGVVVPPEQVEVFRGDGSYIIT
MLBr_01229|M.leprae_Br4923 HNTANAVRLVAGAGHTGKVLLDVPHTGSSVAVVPPEQVRTFRADGAYIVT
MAB_3148c|M.abscessus_ATCC_199 QEAAESIRVMGAAGHTGKLVLDLPKAGEVSAVIPPSHAPAFRRDGAYVVT
MSMEG_4727|M.smegmatis_MC2_155 EEAATAIRIMGGAQHTGKLVIDIPDTGQSQVVVPPEQVPVFRGDGAYVIT
Mflv_3391|M.gilvum_PYR-GCK ----------------------------------------VRGDGSYVVT
Mvan_3124|M.vanbaalenii_PYR-1 ----------------------------------------VRRDGAYVVT
.* **:*::*
TH_4621|M.thermoresistible__bu GGMGGLGLYLAGEMAAAG--AGC--IVLNGRSAPSGEALRTIEQLRAAGT
MAV_2370|M.avium_104 GGLGGLGLFLAEKMASPGSRAGCGRIVLCSRALPNPKALATLERIRQMGA
Mb1554c|M.bovis_AF2122/97 GGLGGLGLFLAEKMANAG----AGRIVLSSRSQPSQKALETIELVRAIGS
Rv1527c|M.tuberculosis_H37Rv GGLGGLGLFLAEKMANAG----AGRIVLSSRSQPSQKALETIELVRAIGS
MMAR_2340|M.marinum_M GGLGGLGLFLAEKMATAG----AGRIVLSSRSAPSQKALETIELIRSIGS
MUL_2010|M.ulcerans_Agy99 GGLGGLGLFFASKMAAAG----CGRIVLTARSQPNPKSRQAIERLRANGA
MLBr_01229|M.leprae_Br4923 GGLTGLGLFLGTEMAAAG----CGRIVLNSRSAPNPQAQETIERLRAGGA
MAB_3148c|M.abscessus_ATCC_199 GGLGGLGLFLARKLAAAG----VGRIILNGRSAPKPEALAAIEQIRQGGT
MSMEG_4727|M.smegmatis_MC2_155 GGLGGLGLFLAERMAAAG----CGRIVVNSRSAPSTRSSEIIELIRATGA
Mflv_3391|M.gilvum_PYR-GCK GALGGVGLAVVRWLVDHG----AGRLVLNGRSGPSPEAQAVIDELSAR-A
Mvan_3124|M.vanbaalenii_PYR-1 GALGGVGMAVVRWLVDHG----AGRLVLNGRSGPSDEVAAELDTLSHR-A
*.: *:*: . :. * ::: .*: *. . :: : :
TH_4621|M.thermoresistible__bu EVIVECGXXXRG----QPVEVAVPT------ELRHADEHPDRRGAQLCDE
MAV_2370|M.avium_104 DIVVERGDIAEAGTAQRLLDVATATGLPVRGVLHLAAVIEDATLANITDE
Mb1554c|M.bovis_AF2122/97 DVVVECGDIAQPDTADRLVTAATATGLPLRGVLHAAAVVEDATLANITDE
Rv1527c|M.tuberculosis_H37Rv DVVVECGDIAQPDTADRLVTAATATGLPLRGVLHAAAVVEDATLANITDE
MMAR_2340|M.marinum_M DVVVECGDIAQPATAARLVANATATNLPLRGVLHAAAVVEDATLANITDE
MUL_2010|M.ulcerans_Agy99 DIVVECGNIAEPETADRLVSAATATGLPLRGVLHAAAVVEDATLSNITDE
MLBr_01229|M.leprae_Br4923 DIQVECGDIAEPRVADRLVVAATQSGLPVRGVLHAAGVVEDATLTNVTDD
MAB_3148c|M.abscessus_ATCC_199 EIDVALGDIAEPDTAQRLVAAATETGKPVRGVLHAAALVHDATLANITDE
MSMEG_4727|M.smegmatis_MC2_155 DIVVECGDIAEPDTALRLVAAATQTGLPLRGVLHAAAVVEDATLANITDE
Mflv_3391|M.gilvum_PYR-GCK EIAVVTGDIAVPGTAVRLIAAAEETGRPLRGVLHSAAVLDDELVVGLTRE
Mvan_3124|M.vanbaalenii_PYR-1 EIAVVTGDVAEPGVAERLVAAAEETGKPLRGLIHSAAVLEDEIFVGMTRE
:: * * : : * : :: * * : :
TH_4621|M.thermoresistible__bu FARG-EQGAQR----NQHRTDAGEG-QRD--------AHPPGAVGHDQPD
MAV_2370|M.avium_104 LIER-DWAAKVYGAWNLHCALQESG-AEQSLDWFCSFSSAAALVGSPGQG
Mb1554c|M.bovis_AF2122/97 LIER-DWAPKAYGAWQLHRATAD-----QPLDWFCSFSSAAALVGSPGQG
Rv1527c|M.tuberculosis_H37Rv LIER-DWAPKAYGAWQLHRATAD-----QPLDWFCSFSSAAALVGSPGQG
MMAR_2340|M.marinum_M LLDR-DWAPKVYGAWHLHQATTD-----QPLDWFCSFSSAAAMLGSPGQG
MUL_2010|M.ulcerans_Agy99 LIDR-DWSPKVYGSWNLHRASTG-----QPLDWFCLFSSGAALMGSPGQG
MLBr_01229|M.leprae_Br4923 LIDR-CWAPKVYGAWNLHQALQEGK-TAQLLDWFCSFSTAAALVGSPGQG
MAB_3148c|M.abscessus_ATCC_199 LIDRGDWRPKVHGAWNLHEATAD-----QPLDWFCSFSSIAALVGSPGQG
MSMEG_4727|M.smegmatis_MC2_155 LVEH-DWAPKVYGAWNLHQAVQSGGPATSELDWFCAFSSAAALVGSPGQG
Mflv_3391|M.gilvum_PYR-GCK SMEK-IWAPKAAGAWRLHEATAG-----KELDWWVAFSSVASLLGSPGQS
Mvan_3124|M.vanbaalenii_PYR-1 SLDK-IWAPKAAGALRLHEVTAG-----SDLDWWVGFSSIVSLLGSPGQA
.: . * . . : . :*
TH_4621|M.thermoresistible__bu PGALSDTGLDERGGQFPGVGVQIPVADPGVGIDH-RGAVRVDSGVPAQQG
MAV_2370|M.avium_104 AYAAANSWLDAFTRWRRARGLKATAIAWGAWAQIGRGAALADSADVAITP
Mb1554c|M.bovis_AF2122/97 AYAAANSWLDTFTHWRRAQDLPATSIAWGAWGQIGRAIAFAEQTGDAIAP
Rv1527c|M.tuberculosis_H37Rv AYAAANSWLDTFTHWRRAQDLPATSIAWGAWGQIGRAIAFAEQTGDAIAP
MMAR_2340|M.marinum_M AYAAANSWLDAFTHWRHNQNQPATAIAWGPWAEIGRAIALAESSDAAIAP
MUL_2010|M.ulcerans_Agy99 AYAAANSWVDAFAHWRRAQGLPVCAIGWGAWGEVGRATFLAEGGEIMIAP
MLBr_01229|M.leprae_Br4923 AYAAANSWLDGFSYWRRAQGLASTTIAWGAWGELGLATALAEMAGVAIAP
MAB_3148c|M.abscessus_ATCC_199 AYAAANSWLDGFTHWRRAQGLPATVIAWGAWSEIGQGTHLAQNAEAAILP
MSMEG_4727|M.smegmatis_MC2_155 AYAAANSWLDAFMQWRRAQGLPATSIAWGAWGEIGRGTAMAE-GDNAIAP
Mflv_3391|M.gilvum_PYR-GCK AYACANAWLDALVTWRAAAGLPATTVNWGQWADVGLASSLRFSVLDPITP
Mvan_3124|M.vanbaalenii_PYR-1 AYACANAWLDGLVAWRTAAGLPALAVNWGQWADVGLASTLRFSVLDPITP
. * ::: :* . * : .
TH_4621|M.thermoresistible__bu VDGEVVRHRTLSSVRSGR-------SSRWTAP---GSR--CGSGR-----
MAV_2370|M.avium_104 DEGAYAFEALLRHDRACTGYAPITGTPWLTAF---AQRSPFAEAF-----
Mb1554c|M.bovis_AF2122/97 EEGAYAFETLLRHNRAYSGYAPVIGSPWLTAF---AQHSPFAEKF-----
Rv1527c|M.tuberculosis_H37Rv EEGAYAFETLLRHNRAYSGYAPVIGSPWLTAF---AQHSPFAEKF-----
MMAR_2340|M.marinum_M DEGAYAFQTLLRHNRTYTGYAPIIGAPWVTAF---AERSKFAEAF-----
MUL_2010|M.ulcerans_Agy99 DEGMYAFEQMLRHARTYTGYIPIIGAPWLADL---VRRSPWAEMF-----
MLBr_01229|M.leprae_Br4923 TEGARVFQTLLRYNRPYSCYAPIMETPWLKSF---AQHSRFAEAF-----
MAB_3148c|M.abscessus_ATCC_199 DEGAYAFDTVLRHNRAYTAYAPMAGISWLADF---VERSPFAQAF-----
MSMEG_4727|M.smegmatis_MC2_155 DEGAYAFEAILRHDRVYNGYAPVLGASWLTAF---AQRSPFAELF-----
Mflv_3391|M.gilvum_PYR-GCK DEGVEALGGVMAAGLTRVGIARLRLDRAAAAFPEIQQIGFFADLVSELDT
Mvan_3124|M.vanbaalenii_PYR-1 AEGVEALGGVMAAGFSRVGIARLRLDRAAAAFPEIQQIGFFADLVGELET
:* . : ..
TH_4621|M.thermoresistible__bu RYGGESCRRTTGPAAGAAARRGR-----------------TRRRRRPRRP
MAV_2370|M.avium_104 RANGQSATGTSKLRAELEELPPEEWSTRLRRLISDQVSLILRRNVDPDRP
Mb1554c|M.bovis_AF2122/97 QSLGQNRSGTSKFLAELVDLPREEWPDRLRRLLSKQVGLILRRTIDTDRL
Rv1527c|M.tuberculosis_H37Rv QSLGQNRSGTSKFLAELVDLPREEWPDRLRRLLSKQVGLILRRTIDTDRL
MMAR_2340|M.marinum_M KALEQGRSGSSKFRSELDALPLDEWPGQLRRMVAEQVSLILRRTIDPDRQ
MUL_2010|M.ulcerans_Agy99 QSSGQNTRGPSKFLAELKLLPQEEWAGRLRRLIAEQASVILRRTVDADRP
MLBr_01229|M.leprae_Br4923 RSISQGQKDKSKFLAELKVLPRDEWPSMIRRLVSEQISLLLRRTIDPDRL
MAB_3148c|M.abscessus_ATCC_199 RDAGQNQTETNKFLDELRALPREEWPTRLRKLVAEQVGLVLRRSIDPDRS
MSMEG_4727|M.smegmatis_MC2_155 LADTQGASETRKLRSELAALPREEWPTHLRRLIAEQVGLLLRRTVDPDRP
Mflv_3391|M.gilvum_PYR-GCK DDADDDWEGAEALKTMSAAEINRVVVARLRRRIAGVMGYSNDSAVDTAKP
Mvan_3124|M.vanbaalenii_PYR-1 DDVDEDWGGVEALKSMDAAEVNRVVVARLRRRISAIMGYSDDNAVDTAQP
:. . :
TH_4621|M.thermoresistible__bu PPPP-----------DRVRHRAGP--------AHGPVRR-----------
MAV_2370|M.avium_104 LPEYGLDSLGGLELLTRIQTETGIRVSPADIAAIGTIRGLADLLRDKLTP
Mb1554c|M.bovis_AF2122/97 LSEYGLDSLSSQELRARVEAETGIRISATEIN--TTVRGLADLMCDKLAA
Rv1527c|M.tuberculosis_H37Rv LSEYGLDSLSSQELRARVEAETGIRISATEIN--TTVRGLADLMCDKLAA
MMAR_2340|M.marinum_M LSEYGLDSLGNLELRTRVQSETGIRISSTDI---TTVRGLADHLFAQLAP
MUL_2010|M.ulcerans_Agy99 FVEYGLDSLGMLEMRTHIETETGVRLSPKVIASHNTARALSQHLADTLAE
MLBr_01229|M.leprae_Br4923 LSDYGLDSLGNLELRTRIETETGIRISPTKIT---TIRSLAEHLCEELAA
MAB_3148c|M.abscessus_ATCC_199 LPDYGLDSLGNLEIRTRIQADTGVRIGPADVS---TVRSLAAHIYDRLAE
MSMEG_4727|M.smegmatis_MC2_155 LSEYGLDSLGHLELRTRIETETGVRVSAMDMT---TIRGLAQRLCEMLDT
Mflv_3391|M.gilvum_PYR-GCK LTEMGLDSLMAVRMRNTIRGDFGVEPPVALLLQGATLNDVALDLIRQLGL
Mvan_3124|M.vanbaalenii_PYR-1 LTELGLDSLMAVRMRNTIRGDFGVEPPVALLLQGATLADLALDLIRQLGL
:. * .
TH_4621|M.thermoresistible__bu ------------------------------------
MAV_2370|M.avium_104 AGAAQAERV---------------------------
Mb1554c|M.bovis_AF2122/97 DRDAPAPA----------------------------
Rv1527c|M.tuberculosis_H37Rv DRDAPAPA----------------------------
MMAR_2340|M.marinum_M EEAAASSQ----------------------------
MUL_2010|M.ulcerans_Agy99 EEAQPAAS----------------------------
MLBr_01229|M.leprae_Br4923 TEAESAVTAT--------------------------
MAB_3148c|M.abscessus_ATCC_199 QESEVASS----------------------------
MSMEG_4727|M.smegmatis_MC2_155 DDAVSAPS----------------------------
Mflv_3391|M.gilvum_PYR-GCK AEEDGSDRPNALRDRAQQRAAARQRAASRRKVGPRS
Mvan_3124|M.vanbaalenii_PYR-1 EEQESAERPNALRERAQQRAAARQRAASRRKVGPRS