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MPSPAGRLHRIRYIRLKKSSPDCRATITSGSADGQRRSPRLTNLLVVAAWVAAAVIANLLLTFTQAEPHD TSPALLPQDAKTAAATSRIAQAFPGTGSNAIAYLVVEGGSTLEPQDQPYYDAAVGALRADTRHVGSVLDW WSDPVTAPLGTSPDGRSATAMVWLRGEAGTTQAAESLDAVRSVLRQLPPSEGLRASIVVPAITNDMPMQI TAWQSATIVTVAAVIAVLLLLRARLSVRAAAIVLLTADLSLAVAWPLAAVVRGHDWGTDSVFSWTLAAVL TIGTITAATMLAARLGSDAGHSAAPTYRDSLPAFALPGACVAIFTGPLLLARTPALHGVGTAGLGVFVAL AASLTVLPALIALAGASRQLPAPTTGAGWTGRLSLPVSSASALGTAAVLAICMLPIIGMRWGVAENPTRQ GGAQVLPGNALPDVVVIKSARDLRDPAALIAINQVSHRLVEVPGVRKVESAAWPAGVPWTDASLSSAAGR LADQLGQQAGSFVPAVTAIKSMKSIIEQMSGAVDQLDSTVNVTLAGARQAQQYLDPMLAAARNLKNKTTE LSEYLETIHTWIVGFTNCPDDVLCTAMRKVIEPYDIVVTGMNELSTGADRISAISTQTMSALSSAPRMVA QMRSALAQVRSFVPKLETTIQDAMPQIAQASAMLKNLSADFADTGEGGFHLSRKDLADPSYRHVRESMFS SDGTATRLFLYSDGQLDLAAAARAQQLEIAAGKAMKYGSLVDSQVTVGGAAQIAAAVRDALIHDAVLLAV ILLTVVALASMWRGAVHGAAVGVGVLASYLAALGVSIALWQHLLDRELNALVPLVSFAVLASCGVPYLVA GIKAGRIADEATGARSKGAVSGRGAVAPLAALGGVFGAGLVLVSGGSFSVLSQIGTVVVLGLGVLITVQR AWLPTTPGRR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2942 | mmpL7 | - | 100% (920) | CONSERVED TRANSMEMBRANE TRANSPORT PROTEIN MMPL7 |
| M. tuberculosis H37Rv | Rv2339 | mmpL9 | 7e-65 | 25.76% (916) | transmembrane transport protein MmpL9 |
| M. tuberculosis H37Rv | Rv0676c | mmpL5 | 9e-63 | 24.11% (896) | transmembrane transport protein MmpL5 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2967 | mmpL7 | 0.0 | 100.00% (920) | transmembrane transport protein MmpL7 |
| M. gilvum PYR-GCK | Mflv_3435 | - | 2e-62 | 25.40% (937) | transport protein |
| M. leprae Br4923 | MLBr_00137 | mmpL7 | 0.0 | 68.56% (881) | hypothetical protein MLBr_00137 |
| M. abscessus ATCC 19977 | MAB_1520c | - | 1e-108 | 30.08% (901) | MmpL family membrane protein |
| M. marinum M | MMAR_1764 | mmpL7 | 0.0 | 59.07% (899) | transmembrane transport protein MmpL7 |
| M. avium 104 | MAV_5284 | - | 1e-105 | 30.94% (905) | membrane protein, MmpL family protein |
| M. smegmatis MC2 155 | MSMEG_0576 | - | 1e-63 | 25.93% (910) | MmpL4 protein |
| M. thermoresistible (build 8) | TH_3056 | - | 1e-70 | 25.97% (924) | PUTATIVE Mmp14a protein |
| M. ulcerans Agy99 | MUL_2007 | mmpL7 | 0.0 | 58.80% (898) | transmembrane transport protein MmpL7 |
| M. vanbaalenii PYR-1 | Mvan_3189 | - | 4e-63 | 25.40% (933) | transport protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3435|M.gilvum_PYR-GCK -----------MSAPVSDARTDEFPAAHGPHRSFIPRMIRLFAVPIILGW
Mvan_3189|M.vanbaalenii_PYR-1 -----------MSAPVSDARTDEFPAARQPHRPFIPRMIRLFAVPIILGW
TH_3056|M.thermoresistible__bu -------------MSVLDR------VGVEPRRPRVASFIRRYSVLIILGW
MSMEG_0576|M.smegmatis_MC2_155 -----------MIQGLHNR---------SDSRPLLPHALRVLAIPVILFW
MAB_1520c|M.abscessus_ATCC_199 ---------------------------MWD---AIARFSSRYAVLIIGLW
MAV_5284|M.avium_104 ---------------------------MPDRPGILGRLTGRYALLVVGLW
Rv2942|M.tuberculosis_H37Rv MPSPAGRLHRIRYIRLKKSSPDCRATITSGSADGQRRSPRLTNLLVVAAW
Mb2967|M.bovis_AF2122/97 MPSPAGRLHRIRYIRLKKSSPDCRATITSGSADGQRRSPRLTNLLVVAAW
MLBr_00137|M.leprae_Br4923 -----------------------------MSTDDSHRSLRLANLLVITAW
MMAR_1764|M.marinum_M -----------------------------MSTDGTHRSSRLVNFLIVAAW
MUL_2007|M.ulcerans_Agy99 -----------------------------MSTDGTHRSSRLVNFLIVAAW
. :: *
Mflv_3435|M.gilvum_PYR-GCK IALIVVVNVTVPQLETVGEAQAVSMSPNDAPSMISMKKVGELFEEGDSDS
Mvan_3189|M.vanbaalenii_PYR-1 IALIVILNVTVPQLEAVGEARAVSMSPNEAPSLISMKKVGELFREGDSDS
TH_3056|M.thermoresistible__bu VALTVLATVAVPPLEAVEREKSLSLIPYDAPAFAAMHRMGELFDEPDSES
MSMEG_0576|M.smegmatis_MC2_155 VAFAAVVNIIAPQLEIVGEEHSAPMAPEDAPSLTGMHRMGGNFQEFDSNS
MAB_1520c|M.abscessus_ATCC_199 VLLAGAGNLLVPQVESTAHNHARGFLPQDAPVNAAGAVMGRQFQDGAGNN
MAV_5284|M.avium_104 VLAAAVANVAVPQLERVVDSHARSFMPPSAPSAVAAARAAQLFDQTPSNN
Rv2942|M.tuberculosis_H37Rv VAAAVIANLLLTFTQAEPHDTSPALLPQDAKTAAATSRIAQAFPGTGSNA
Mb2967|M.bovis_AF2122/97 VAAAVIANLLLTFTQAEPHDTSPALLPQDAKTAAATSRIAQAFPGTGSNA
MLBr_00137|M.leprae_Br4923 ITAVVIANLIFTLTQAKLRDKNSVLLPQDTMTVTTTNQIAQAFPGTGTNA
MMAR_1764|M.marinum_M IAVAVIANLAVVLAPGKSSDAGSALLSPDSTASAASSRIGQAFPGTGTNA
MUL_2007|M.ulcerans_Agy99 IAVAVIANLAVVLAPGKSSDAGSALLSPDSTASAASSRIGQAFPGTGTNA
: .: : . .: . * :
Mflv_3435|M.gilvum_PYR-GCK SVMIVFEGDQPLGDEAHAWYDELVDRLEADTAHVQSVQDFWSDPLTASGS
Mvan_3189|M.vanbaalenii_PYR-1 SVMIVFEGDQPLGDEAHAWYDELVERLRADTKHVQSVQDFWSDPLTASGS
TH_3056|M.thermoresistible__bu IAIIVLEGQEPLGLEAHEYYDQLISQLREHPQYVQHIRDFWGDPLTAGAA
MSMEG_0576|M.smegmatis_MC2_155 TVMVVIEGQEPLGPDAHAYYDEIIRKLRQDPEHIQHIQDFWGDTLTAAGA
MAB_1520c|M.abscessus_ATCC_199 LNYLVLESDHKLGPVEHQYHDRLLTTLRADTTHLDSAMDLWADPLTAEGA
MAV_5284|M.avium_104 FVYVVLERNQRLGAGDRQFYDALAAALGSDHRHVYAVTDLWSQPATAAGA
Rv2942|M.tuberculosis_H37Rv IAYLVVEGGSTLEPQDQPYYDAAVGALRADTRHVGSVLDWWSDPVTAPLG
Mb2967|M.bovis_AF2122/97 IAYLVVEGGSTLEPQDQPYYDAAVGALRADTRHVGSVLDWWSDPVTAPLG
MLBr_00137|M.leprae_Br4923 IAYLVVEGNRTLEPEDQPYYDSAVNALRADTHDVGSVLDWWSDPLTAPLG
MMAR_1764|M.marinum_M VAYLVVDGPDTLGPADQSYYDAAVNALRADSRHIGSVLDWWSDPLTVPLG
MUL_2007|M.ulcerans_Agy99 VAYLVVDGPDTLGPADQSYYDAAVNALRADSRHIGSVLDWWSDPLTVPLG
:*.: * : ::* * . : * *.:. *. .
Mflv_3435|M.gilvum_PYR-GCK QSNDGKAAYVQVKLSGNQGEALANESVKAVQQTVSSLEPPPGVRAFVTGP
Mvan_3189|M.vanbaalenii_PYR-1 QSNDGKAAYVQVKLAGNQGESLANESVQAAQEIVRSLEPPPGVRAFVTGP
TH_3056|M.thermoresistible__bu QSDDGKAAFVQVNLVGRFGQAKVNEAVRAVQEIVERTPAPEGVETFVTGP
MSMEG_0576|M.smegmatis_MC2_155 QSADGKAAYVMLNLAGEQGQTLANDGVQEVRQVIADTPAPPGVQAYAAGP
MAB_1520c|M.abscessus_ATCC_199 LSPDGKAVYTMLRVNGELGAAKANDALAAVRKIVADQPAPPGTQAWVTGP
MAV_5284|M.avium_104 QSTDGQAVSVMVRLAGMLGTAQARDSVNAVRATAQKLGPPAGLQVHVTGP
Rv2942|M.tuberculosis_H37Rv TSPDGRSATAMVWLRGEAGTTQAAESLDAVRSVLRQLPPSEGLRASIVVP
Mb2967|M.bovis_AF2122/97 TSPDGRSATAMVWLRGEAGTTQAAESLDAVRSVLRQLPPSEGLRASIVVP
MLBr_00137|M.leprae_Br4923 TSPDSRSAIALIWLQGEAGTTRARASLGAIRSVVRQLPPSEELRARIVVP
MMAR_1764|M.marinum_M TGSDGHSAMAMVWLVGQAGSTQARESLQAAQSVVHNLPASAGLRARVVGP
MUL_2007|M.ulcerans_Agy99 TGSDGHSAMAMVWLVGQAGSTQARESLQAAQSVVHNLPASARLRARVVGP
. *.::. . : : * * : . .: : .. .. . *
Mflv_3435|M.gilvum_PYR-GCK AALAADQHIAGDRSMRLIEAATFTVIIVMLLLVYRSIVTVLITLVMVVMS
Mvan_3189|M.vanbaalenii_PYR-1 AALAADQHIASDRSVRVIELVTFAVIIVMLLLVYRSIVTVLLTLVMVVLS
TH_3056|M.thermoresistible__bu AALGADAGDSGTATVILITLVTVAVIFLMLLFFFRSFLTVIVLLLTVAVE
MSMEG_0576|M.smegmatis_MC2_155 AALTDDLHVIGNASLGKITLFTLVAIAVMLLIVYRSIVTTLIQLVLTGVG
MAB_1520c|M.abscessus_ATCC_199 GATIADELTAIDTQMLMITGVTVVLIAVLLFVVYRSVITAAIPLMTVGLG
MAV_5284|M.avium_104 GATIVDEFSAIDRQMLGITAATIGLILLLLLVVYRSPVAAAIPLISVGLA
Rv2942|M.tuberculosis_H37Rv AITNDMPMQITAWQSATIVTVAAVIAVLLLLRARLSVRAAAIVLLTADLS
Mb2967|M.bovis_AF2122/97 AITNDMPMQITAWQSATIVTVAAVIAVLLLLRARLSVRAAAIVLLTADLS
MLBr_00137|M.leprae_Br4923 ATTNNMPMEMTAWQGMAIVTAAAVIAILFLLRARQAIRIVVIMLLTADFS
MMAR_1764|M.marinum_M TTSSSVPAHMTVWQGAVIVLATAVIAVLLLLWARRSLVAAAVVLLTAGLS
MUL_2007|M.ulcerans_Agy99 TTSSSVPAHMTVWQGAVIVLATAVIAVLLLLWARRSLVAAAVVLLTAGLS
* : ::*: : . : *: . .
Mflv_3435|M.gilvum_PYR-GCK LATARGVVAFLG---HHEIIGLSTFATNLLVTLAIAAATDYAIFLIGRYQ
Mvan_3189|M.vanbaalenii_PYR-1 LATARGVVAFLG---WHEIIGLSLFATNLLVTLAIAAATDYAIFLIGRYQ
TH_3056|M.thermoresistible__bu LQVARGLVAYLG---LQGWVGLTTYVVNLLVSVGIAAGTDYGIFFFGRYQ
MSMEG_0576|M.smegmatis_MC2_155 LLASRGLISVLA---THDVFGLTTFAGNILTMLAIAAATDYGIFLFGRYR
MAB_1520c|M.abscessus_ATCC_199 LAVARSIVAFLG---ERDLIEVSIFSVSLLAALVLGAATDYGIFLLGRYH
MAV_5284|M.avium_104 LALARAVVAALG---QANVVEVSLFSVALMAAMTLGAGTDYAIFLVGRYH
Rv2942|M.tuberculosis_H37Rv LAVAWPLAAVVR---GHDWGTDSVFSWTLAAVLTIGTITAATMLAARLGS
Mb2967|M.bovis_AF2122/97 LAVAWPLAAVVR---GHDWGTDSVFSWTLAAVLTIGTITAATMLAARLGS
MLBr_00137|M.leprae_Br4923 LAAAWPLAAVVQ---RQTGGTVSVFSWNLAAVLTIGTITASTLLASR--S
MMAR_1764|M.marinum_M LAVAWPLAAALRAIPGQNISVFTVFSATLAAVLTIGAIAASTMLVARPGH
MUL_2007|M.ulcerans_Agy99 LAVAWPLAAALRAIPGQNISVFTVFSATLAAVLTIGAIAASTMLVARPGH
* : : : : : : : . : :.: : ::
Mflv_3435|M.gilvum_PYR-GCK EARTAGEDKETAYYTMFHGTAHVVLGSGLTIAGATFCLSFTRLPYFQTMG
Mvan_3189|M.vanbaalenii_PYR-1 EARTNGEDKESAYYTMFHGTAHVVLGSGLTIAGATYCLSFTRLPYFQTLG
TH_3056|M.thermoresistible__bu EAREAGEDRDSAYFTTYRSVAKVVLASGLTIAGAIACLSFTRLPHFQPLG
MSMEG_0576|M.smegmatis_MC2_155 EARGAGEDPETAYYTTFKSVSPVIVGSGLTIAGATYCLSFARLPYFSTMG
MAB_1520c|M.abscessus_ATCC_199 EQRRSGVDHEQALVIANRSVAPVIAASGLTIAAALSCLLFAQVGMLRSAG
MAV_5284|M.avium_104 EARRGGVAPAQALTVAYRSIAPVVIGSALTVSVALACLVFAHVGSFRSAG
Rv2942|M.tuberculosis_H37Rv DAGHSAAP-------TYRDSLPAFALPGACVAIFTGPLLLARTPALHGVG
Mb2967|M.bovis_AF2122/97 DAGHSAAP-------TYRDSLPAFALPGACVAIFTGPLLLARTPALHGVG
MLBr_00137|M.leprae_Br4923 YTGDSAAP-------TCRAHLPALALLGACVALLTGTLLLARTPALHSVG
MMAR_1764|M.marinum_M APGATAAQP--LGRSASRDNLAALAMPAAGVAILTAPLLLARTPALHGVG
MUL_2007|M.ulcerans_Agy99 APGATAAQP--LGRSASRDNLAALAMPAAGVAILTAPLLLARTPALHGVG
. : .. . :: * ::: : *
Mflv_3435|M.gilvum_PYR-GCK VPLAIGMFVVVMAGVVLMVACISVATRFGKLLEPKRA-MRIRGWRKIGAA
Mvan_3189|M.vanbaalenii_PYR-1 VPLAIGMFVVVMAGVILMVAMISVATRFGKLLEPKRA-MRIRGWRKIGAA
TH_3056|M.thermoresistible__bu IPGAVGLLVAVAVALTLVPATIALGSRFG-LFEPKRR-VMTHRWRRIGTA
MSMEG_0576|M.smegmatis_MC2_155 APVAIGMIVVVASSVTMGPAVLFLGSKVG-LYEAKRA-AKGRFWRRVGTA
MAB_1520c|M.abscessus_ATCC_199 LPCAIGILTGMVASLTLLPALIGLAGRRGLAQPRPLRGQPGRRWRRVGAM
MAV_5284|M.avium_104 LPCAIGILATMVAALTLTPALMSLAVRRRYLEPRPSR--TARRWRRVGTT
Rv2942|M.tuberculosis_H37Rv T-AGLGVFVALAASLTVLPALIALAGASRQLPAPTTG------AGWTGRL
Mb2967|M.bovis_AF2122/97 T-AGLGVFVALAASLTVLPALIALAGASRQLPAPTTG------AGWTGRL
MLBr_00137|M.leprae_Br4923 T-VALGVVVALAASLTLLPTLIKLAGPSGQISPQVNG------NTWTRRL
MMAR_1764|M.marinum_M V-AALGVVVALAASLTLLPALIGLTGPSRLSSSRPVG------ARRTLPV
MUL_2007|M.ulcerans_Agy99 V-AALGVVVALAASLTLLPALIGLTGPSRLSSSRPVG------ARRTLPV
.:*:.. : .: : : : :
Mflv_3435|M.gilvum_PYR-GCK IVRWPGPILVATMAITLVGLLALPGYKTNYNDRDYLPADLPANQGYAVAD
Mvan_3189|M.vanbaalenii_PYR-1 VVRWPGPILVATLAITLVGLLALPGYKTNYNDRTYLPADLPANEGYAVAD
TH_3056|M.thermoresistible__bu VVRWPVPILTAAVALSLVGLLTLPGYNPSYSDQEFIPDDIPASEGYKAAA
MSMEG_0576|M.smegmatis_MC2_155 VVRWPAPILVASAFIVLIGVVAVPGYRPAYNDRWYLPDDAPVNIGFAAAD
MAB_1520c|M.abscessus_ATCC_199 VSRWPGPVLAGSLLVLVVCALPVAGLRLGFDELAAQPLSTHANRGYQAMD
MAV_5284|M.avium_104 VARWPGPILVAALGLTLLVALPLAGMRIGFNEPAATPSSTDSNRGYASAG
Rv2942|M.tuberculosis_H37Rv SLPVSSASALGTAAVLAICMLPIIGMRWGVAEN---PTRQGG-------A
Mb2967|M.bovis_AF2122/97 SLPVSSASALGTAAVLAICMLPIIGMRWGVAEN---PTRQGG-------A
MLBr_00137|M.leprae_Br4923 LVPNFSSPARLTAVVLATCALPVIGMRLGLAED---HTAQSG-------T
MMAR_1764|M.marinum_M SIPR---TAVVAALVLAVCAVPVIGMQWGIGDGPVNPAAGGT-------K
MUL_2007|M.ulcerans_Agy99 SLPR---TAVVAALVLAVCAVPVIGMQWGIGDGPVNPAAGGT-------K
: : :.: * . :
Mflv_3435|M.gilvum_PYR-GCK EHFDQARMN-PELLMIESDHDLRNSADFLVIDKIAKALFRVEGIARVQAI
Mvan_3189|M.vanbaalenii_PYR-1 RHFDQARMN-PELLMIESDHDLRNSADFLVIDKIAKAIFKVEGIARVQAI
TH_3056|M.thermoresistible__bu RHFPASAMSVPDVVLIEADRDMRNPADLLVLNKVAKKIFEVPGVANVQSV
MSMEG_0576|M.smegmatis_MC2_155 RHFTQARMN-PDILMVEADHDMRNPADMLVLDRVAKNVLRTQGIAMVQSI
MAB_1520c|M.abscessus_ATCC_199 RHFPPNRLL-PEIVSIESDHDLRTPAGVIAVERVTKGLMEIPGIRMVQSA
MAV_5284|M.avium_104 RHFPENALL-PDVIAIRADHDLRNPAGLIAIERITRHIMAVPGVRAVQSA
Rv2942|M.tuberculosis_H37Rv QVLPGNALP--DVVVIKSARDLRDPAALIAINQVSHRLVEVPGVRKVESA
Mb2967|M.bovis_AF2122/97 QVLPGNALP--DVVVIKSARDLRDPAALIAINQVSHRLVEVPGVRKVESA
MLBr_00137|M.leprae_Br4923 QILPGNLLP--DILLIKSARDLRDPAALIAIDQVSHRLMEIPGVRKVESA
MMAR_1764|M.marinum_M RALPWQPLP--DVVMLEAKHDLSDPAGLIAIDQVSHRLMEIPGVRRVESA
MUL_2007|M.ulcerans_Agy99 RALPWQPLP--DVVMLEAKHDLSDPAGLIAIDQVSHRLMEIPGVRRVESA
. : : ::: :.: :*: .* .:.:::::: :. *: *::
Mflv_3435|M.gilvum_PYR-GCK TRPDGKPIKHTSIPFQMSMQGTTQRLNEKYMQDRMADMLVQADEMANTIK
Mvan_3189|M.vanbaalenii_PYR-1 TRPDGKPIKHTSIPFQMSMQGTTQRLNEKYMQDRMADMLVQADEMANTIA
TH_3056|M.thermoresistible__bu TRPEGRQIEHTTIPFMLSMSQASQRLALPFQRARMDDMLKQADELTETIA
MSMEG_0576|M.smegmatis_MC2_155 TRPLGIPIQHSSIPFQTAIQGQTSNLNLPFQRAQLDNQLKMVEATNQSIA
MAB_1520c|M.abscessus_ATCC_199 SRPAGTIPEQAALTEQAGIIADQLDDGTAQMSQRLGAVDKLSATLSQFSG
MAV_5284|M.avium_104 SRPDGKVPEQATLSYQAGVLGRQFGDTVDSLTQRLARVSELDGALAQTQQ
Rv2942|M.tuberculosis_H37Rv AWPAGVPWTDASLSSAAGRLADQLGQQAGSFVPAVTAIKSMKSIIEQMSG
Mb2967|M.bovis_AF2122/97 AWPAGVPWTDASLSSAAGRLADQLGQQAGSFVPAVTAIKSMKSIIEQMSG
MLBr_00137|M.leprae_Br4923 AWPAGVPWNDASLSSAAGRLADQMSQQAGSFVPAVTAIKQMKTMIDQMSS
MMAR_1764|M.marinum_M AWPAGVPWTDASLTAAAGKLSDELDRGAGSFMPQVRAIKTLGSIVDQMSG
MUL_2007|M.ulcerans_Agy99 AWPAGVPWTDASLTAAAGKLSDELDRGAGSFMPQVRAIKTLGSIVDQMSG
: * * .:::. . : :
Mflv_3435|M.gilvum_PYR-GCK TMEKMSGLTAQMADITHSMVTKMEGMVVDIEDLRDSIANFDDFFRPIRNY
Mvan_3189|M.vanbaalenii_PYR-1 TMEKMSNLTAQMADITHSMVSKMENMLTDIEDLRDSIANFDDFFRPIRNY
TH_3056|M.thermoresistible__bu LMRRMQSLMEKMVATTHSMVGTTHELLDTTRDLRDHIADFDDFFRPIRNY
MSMEG_0576|M.smegmatis_MC2_155 IMEKQYELSLRQTKLTQDSAEKSRELLEVTKQLRDNIANFDDQFRPLRNY
MAB_1520c|M.abscessus_ATCC_199 AIAQLQKGLAGGVNGLGELNGGIGDMHSGMKALQDNVSQVSGYMEPLRNF
MAV_5284|M.avium_104 AVDGLGNGLHGGSAGLADMSGAADDMRAGMDGLQRNVTTVSGYLDPLRDL
Rv2942|M.tuberculosis_H37Rv AVDQLDSTVNVTLAGARQAQQYLDPMLAAARNLKNKTTELSEYLETIHTW
Mb2967|M.bovis_AF2122/97 AVDQLDSTVNVTLAGARQAQQYLDPMLAAARNLKNKTTELSEYLETIHTW
MLBr_00137|M.leprae_Br4923 TVDELESTVNVALAGAHQVQQYLNPVLSAARNIKSKTAEFSGYLDTVRGW
MMAR_1764|M.marinum_M AVDELDRSVTAGLAGAAQIQQNVDLLISGTKNIKGVTVELSGYLDPVRGW
MUL_2007|M.ulcerans_Agy99 AVDELDRSVTAGLAGAAQIQQNVDLLISGTKNIKGVTVELSGYLDPVRGW
: . : :: .. : .::
Mflv_3435|M.gilvum_PYR-GCK FYWEPHCYNIPVCWALRSVFDTLDGINIMTDDFKAIIPDMKRLDTLMPQM
Mvan_3189|M.vanbaalenii_PYR-1 FYWEPHCYNIPVCWALRSVFDTLDGINVMTDDFREILPDMKRLDSLMPQM
TH_3056|M.thermoresistible__bu FHWEPHCYNIPICWSIRSIFDALDGINEMTEKMEELVEDMDRLDALMPQM
MSMEG_0576|M.smegmatis_MC2_155 FYWEPHCFDIPMCAAARSLFDSLDTVDELTDRTSAVQVNTDELADLAPQL
MAB_1520c|M.abscessus_ATCC_199 TNGNPNCANDGICSLVLKAVEPMDSVVAATASLTASTTKFGAGAQGMQKS
MAV_5284|M.avium_104 VGRTPDCAANPICSMVDRVLAPVDSLVQTSAQLGSGAAKLTTGSNTAATA
Rv2942|M.tuberculosis_H37Rv IVGFTNCPDDVLCTAMRKVIEPYDIVVTGMNELSTGADRISAISTQTMSA
Mb2967|M.bovis_AF2122/97 IVGFTNCPDDVLCTAMRKVIEPYDIVVTGMNELSTGADRISAISTQTMSA
MLBr_00137|M.leprae_Br4923 VVSVTNCPNDVLCSAMRKVIEPYDKVAASMDQLSNGVDRISAISDQTISS
MMAR_1764|M.marinum_M MGDVPNCPGDMLCVAAGKVIDPVDRVVDDVKLLTDGADRIAAVSRKTVGA
MUL_2007|M.ulcerans_Agy99 MGDVPNCPGDMLCVAAGKVIDPVDRVVDDVKLLTDGADRIAAVSRKTVGA
..* :* . . * :
Mflv_3435|M.gilvum_PYR-GCK VALMPEMIETMKTMRTMMLTMYQSQKGQQ----DQMAAMSEDADAMGEAF
Mvan_3189|M.vanbaalenii_PYR-1 VALMPEMIETMKTMRTMMLTMYQSQKGQQ----DQMAAMSEDADAMGEAF
TH_3056|M.thermoresistible__bu LVQFPQMIETMESSRTMILTMHATMSGIF----DQMESSSENATAMGKAF
MSMEG_0576|M.smegmatis_MC2_155 TALLPQTIASMKTSRDLSLASYNSQKALL----DQMQAMNDTALAMGQSF
MAB_1520c|M.abscessus_ATCC_199 FSGAVDSVKNMRATVAQLGAITDQLTHAVGETRTMFSGLTEYLRAMREDF
MAV_5284|M.avium_104 MAGLPQNVDAMKSALVQARSATRDLLGLSDTLGPQMRQLTDYLNEISTQF
Rv2942|M.tuberculosis_H37Rv LSSAPRMVAQMRSALAQVRSFVPKLETTIQDAMPQIAQASAMLKNLSADF
Mb2967|M.bovis_AF2122/97 LSSAPRMVAQMRSALAQVRSFVPKLETTIQDAMPQIAQASAMLKNLSADF
MLBr_00137|M.leprae_Br4923 FNEAPHMVAQMRSALKQARSFIPRLESTIQELMPQIAQASAMLKNLSRDF
MMAR_1764|M.marinum_M FSSAPQVVAQMRSALAQLQSFVPNLETTIENTLPQLVQVSAFLKNLRLDF
MUL_2007|M.ulcerans_Agy99 FSSAPHVVAQMRSALAQLQSFVPNLETTIENTLPQLVQVSAFLKNLRLDF
: *.: : : . : *
Mflv_3435|M.gilvum_PYR-GCK DDSMNDDSFYLPPEIFENADFQRGLEQFLSPDGHAVRFIISHEGDPLSPE
Mvan_3189|M.vanbaalenii_PYR-1 DDSMNDDSFYLPPEIFENKDFQRGLEQFLSPDGHAVRFIISHEGDPLSPE
TH_3056|M.thermoresistible__bu DASHNDDSFYLPPEALENKDFQRVMEIFLSPDGKAARMLVTQRGDPATPE
MSMEG_0576|M.smegmatis_MC2_155 DEAKNDDFFYLPPEAFQNPDFERGLKMFLSPDGKSARMFITHQSDPATPE
MAB_1520c|M.abscessus_ATCC_199 RSSGEGG-YYLPQRAWQDPRFQRAAGLYFGPDGHSTRMLVFGDGKVFGAD
MAV_5284|M.avium_104 QGSAAAD-FYLPQRALTDPRYTAVLNHLISQTGRAAYLLVYGDGAEWGAD
Rv2942|M.tuberculosis_H37Rv ADTGEGG-FHLSRKDLADPSYRHVRESMFSSDGTATRLFLYSDGQ-LDLA
Mb2967|M.bovis_AF2122/97 ADTGEGG-FHLSRKDLADPSYRHVRESMFSSDGTATRLFLYSDGQ-LDLA
MLBr_00137|M.leprae_Br4923 ADTGEGG-FHLPMKELMSSSYQHVRESMFSSDGTATRLVVYTNEHNPGLD
MMAR_1764|M.marinum_M ANTGQGG-FYLSGKALADPSYQQVRQSMFSADGTATRLLVFSEGN-PGLD
MUL_2007|M.ulcerans_Agy99 ANTGQGD-FYLSGKALADPSYQQVRQSMFSADGTATRLLVFSEGN-PGLD
: . ::*. . . : :. * :. :.:
Mflv_3435|M.gilvum_PYR-GCK GVAKIDKIKTAAKEAVKGTPLEGSKIYLGGTAAVFKDMQDGNNYDLLIAG
Mvan_3189|M.vanbaalenii_PYR-1 GVAKIDKIKTAAKEAIKGTPLEGSKIYLGGTAATFKDMQDGNNYDLLIAG
TH_3056|M.thermoresistible__bu GMALVEPIYIAAEEALKGTPLESSRIYLAGSAAGVKDLVEGAKYDLMIAA
MSMEG_0576|M.smegmatis_MC2_155 GIARVNAERTAAQEGLKMSSLSDAKIFLGGTAATYKDMSDGARYDLMIAV
MAB_1520c|M.abscessus_ATCC_199 GAHRSPQIMLAVSEATKEGTLAGSSVNLTGFGTGTAELRGYVSEDFLLLA
MAV_5284|M.avium_104 SAERAEQVRAAIKEATKEGTLTPVEVDLAGVGPVTADLQRFVADDTRLLV
Rv2942|M.tuberculosis_H37Rv AAARAQQLEIAAGKAMKYGSLVDSQVTVGGAAQIAAAVRDALIHDAVLLA
Mb2967|M.bovis_AF2122/97 AAARAQQLEIAAGKAMKYGSLVDSQVTVGGAAQIAAAVRDALIHDAVLLA
MLBr_00137|M.leprae_Br4923 TAARAQQLEIAAGKAMKYGSLVDSRITLGGAAQVAVAARAALTHDAVLLA
MMAR_1764|M.marinum_M ASARAQQLEAAAGKAMKYGSLEDAEITVNGAAQVATDVRGSLTHDAVLLA
MUL_2007|M.ulcerans_Agy99 ASARAQQLEAAAGKAMKYGSLEDAEITVNGAAQVATDVRGSLTHDAVLLA
* :. * .* : : * . * :
Mflv_3435|M.gilvum_PYR-GCK IAALGLIFIIMLILTRAVVAAAVIVGTVVLSLAASFGLSVLFWQHILGQP
Mvan_3189|M.vanbaalenii_PYR-1 ISALGLIFIIMLILTRAIVAAAVIVGTVVLSLAASFGLSVLFWQHILGTE
TH_3056|M.thermoresistible__bu ISAVCLIFMIMVFMTRSVIAALVIVGTVVLSLGASFGMSVLLWQHLLGIQ
MSMEG_0576|M.smegmatis_MC2_155 VSALTLIFMIMLILTRSAVAALVIVGTAASSIAASFGISVLLWQDLFGVE
MAB_1520c|M.abscessus_ATCC_199 AVALALVFLIVLVMLRSPVAAAVVIGTVIISYASALGVTTLIWQDLLGRD
MAV_5284|M.avium_104 GAALVLIFLIVTAMLRSPVAGLVVVGTVVTSYASAIGASVLIWQHLLHQE
Rv2942|M.tuberculosis_H37Rv VILLTVVALAS--MWRGAVHGAAVGVGVLASYLAALGVSIALWQHLLDRE
Mb2967|M.bovis_AF2122/97 VILLTVVALAS--MWRGAVHGAAVGVGVLASYLAALGVSIALWQHLLDRE
MLBr_00137|M.leprae_Br4923 GMLFAVVALAS--MWVSAGSGVAVGLGVLAAYLGGLGISVALWQHILGHE
MMAR_1764|M.marinum_M AMMLAAVVLVS--MWRGALTAVVMAVGLLAAYLAALGISTALWQYLAGRE
MUL_2007|M.ulcerans_Agy99 AMMLAAVVLVS--MWRGALTAVVMAVGLLAAYLAALGISTALWQYLAGRE
. : : : . . .: : ..:* : :** :
Mflv_3435|M.gilvum_PYR-GCK LHWMVLAMAVIILLAVGADYNLLLVSRLKEEIH----AGIGTGIIRAMGG
Mvan_3189|M.vanbaalenii_PYR-1 LHWMVLAMAVIVLLAVGADYNLLLVSRLKEEIH----AGIGTGIIRAMGG
TH_3056|M.thermoresistible__bu LHWVVLAMSVIVLLAVGSDYNLMLVSRMKEEIG----AGLNTGIIRAMGG
MSMEG_0576|M.smegmatis_MC2_155 VHWLVMLMSVIILLAVGSDYNLLLVSRFKDEIH----AGLKTGIIRSMAG
MAB_1520c|M.abscessus_ATCC_199 LHWAVPSIALIALVAVGADYNLLLTMRMREEVFLH-GAGLRTGMIRTFGG
MAV_5284|M.avium_104 LHWAVAPIAFIALIAVGADYNLLLALRIKQEA----AAGLRTGIIRAFGG
Rv2942|M.tuberculosis_H37Rv LNALVPLVSFAVLASCGVPYLVAGIKAGRIADEA---TGARSKGAVSGRG
Mb2967|M.bovis_AF2122/97 LNALVPLVSFAVLASCGVPYLVAGIKAGRIADEA---TGARSKGAVSGRG
MLBr_00137|M.leprae_Br4923 LQASVPLVSFAILAPCGVLYLVTSLEAARVSAEA---KTAAT---VSVRR
MMAR_1764|M.marinum_M IPAAVPLVSFAILAACGLPYLLD-RTATPISTEAPITSDAQPADTAALRN
MUL_2007|M.ulcerans_Agy99 IPAAVPLVSFAILAACGLPYLLD-RTATPISTEAPITSDAQPADTAALRN
: * ::. * . * * : . :
Mflv_3435|M.gilvum_PYR-GCK SGSVVTAAGLVFALTMMSMSVSELTVIGQVGTTIGLGLLFDTLVIRAFMT
Mvan_3189|M.vanbaalenii_PYR-1 SGSVVTAAGLVFALTMMSMAVSELTVIGQVGTTIGLGLLFDTLVIRAFMT
TH_3056|M.thermoresistible__bu TGRVVTMAGLVFAATMASMIVSDLLMIGQVGTTIALGLLFDTMVVRAFMT
MSMEG_0576|M.smegmatis_MC2_155 TGGVVTSAGLVFAATMAAMLGSELVVLAQMGSTIAIGLLLDTLIVRSLLM
MAB_1520c|M.abscessus_ATCC_199 TGGVVTTAGIVFGITMFAMLSSDVLSIEQTGTTIGVGLMIDTLIVRTFVV
MAV_5284|M.avium_104 TGGVVTVAGIIFGLTMLALLTSSVLSIAQIGTTIAVGLLLDTLVVRAFIV
Rv2942|M.tuberculosis_H37Rv AVAPLAALGGVFGAGLVLVSGGSFSVLSQIGTVVVLGLGVLITVQRAWLP
Mb2967|M.bovis_AF2122/97 AVAPLAALGGVFGAGLVLVSGGSFSVLSQIGTVVVLGLGVLITVQRAWLP
MLBr_00137|M.leprae_Br4923 AVVPLTVLGAIFGAGLVVAEA-SFSALSQVGTVLVIALGALTKVEQVLIS
MMAR_1764|M.marinum_M AGAPLAALTAVFGLGLVLVSAGSLGALSQIGTVVLFGVAALTVLARVCIP
MUL_2007|M.ulcerans_Agy99 AGAPLAALTAVFGLGLVLVSAGSLGALSQIGTVVLFGVAALTVLARVCIP
: :: :*. : .. : * *:.: ..: : : :
Mflv_3435|M.gilvum_PYR-GCK PSIAALLGPWFWWPQRVRTR-----PVPAPWPRSGGLQSDPSEGVRA---
Mvan_3189|M.vanbaalenii_PYR-1 PSIAALLGPWFWWPQRVRTR-----PVPAPWPRPGGLQSDPSEGVKV---
TH_3056|M.thermoresistible__bu PSVAAILGRWFWWPQRVRTR-----PASAMLRPVGPRPLVRSLLLRD---
MSMEG_0576|M.smegmatis_MC2_155 PSIATLLGRWFWWPQVVYPRGDNHFRRPTAVSRGTGDEDTAALPVPS---
MAB_1520c|M.abscessus_ATCC_199 PAIAGALGKWFWWSPVPLLRGLLFRWSKARSPRTAGVLSYLLTRPSRLER
MAV_5284|M.avium_104 PSIVALLGRWFWW-PSPLPRRGVARVVKTVEPQPVSVATAV---------
Rv2942|M.tuberculosis_H37Rv -----------TTPGRR---------------------------------
Mb2967|M.bovis_AF2122/97 -----------TTPGRR---------------------------------
MLBr_00137|M.leprae_Br4923 YHAEAAMPAWSKLPSRLSGGPN----------------------------
MMAR_1764|M.marinum_M -AAIQDRADRTTVATEPVAQPD----------------------------
MUL_2007|M.ulcerans_Agy99 -AAMQDRADRTTVATEPVAQPD----------------------------
Mflv_3435|M.gilvum_PYR-GCK ---
Mvan_3189|M.vanbaalenii_PYR-1 ---
TH_3056|M.thermoresistible__bu ---
MSMEG_0576|M.smegmatis_MC2_155 ---
MAB_1520c|M.abscessus_ATCC_199 TGA
MAV_5284|M.avium_104 ---
Rv2942|M.tuberculosis_H37Rv ---
Mb2967|M.bovis_AF2122/97 ---
MLBr_00137|M.leprae_Br4923 ---
MMAR_1764|M.marinum_M ---
MUL_2007|M.ulcerans_Agy99 ---