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MSGESRVSAPAPERPAFMRFVRRFAVPILTTWLFMTVAVNVLVPPIESVAREHAVTMSPHDAPAMIAAKH IGQKYHESDSDSIAMIVLESDDPLGERAHQYYDNLVLALQADTRHVQHVQNVWGDPLTASGVQSRDGRAA YVQVNLAGDQGSTLGNKSVVAVREIVDNSTPPQGVTVYVTGPAALTTDMNEAADKSMLIMMGVTGAVIMI MLLITYRSVSTMLLVLVMVGFEMGTARGIVAILGNYDLLGFSTFVVAMLSSLAIAAGTDYAIFLIGRYQE ARQVGQDRENAYYTMFRGTFHIILGSGLTIAGATLCLHLARLSYFKALGIPSALGLLVVVVGALTAAPAV VVVAGRFGLLDPKRPVNVRRWRRIGTATVRWPGAVFAASSAIALVGIAIMPTMKVSYNDRFYIPEDLPSN IGYTAAERHFSSATMNPDILMIESDHDMRNTGDMIILDRIAKEVFRSPGIAMVQSITRPLGGPIEHTSIP FQISAQSIPIQQNLQFMKDRAADMLSMSKDLDALIGAMERMQSLLGQMSSATHRMSANMTDAKTTLEEIR DHLADFDDVVRPLRNYFYWEQHCFDLPACSAIRSVFDALDGVDAFSDKMRALTTDIGNVDAVIPQMAAQL PPIIAVARSMQDTLLTMHSSFSNLITQMAHMTDTASAMGQAFDASRSGDYFYLPPEAFQNPDFQRGLKLF LSPDGTAARFIITHDRDPATPAGISTVTSELEAAHQAVKGTALTDAKFYLAGTAAIYRDIQSGSRYDLLI VGIAAVTLIFAVMMIITRAFVASLAIVGTVLLSLGAAFGISVLVWQHIFGLELNWIAPVFGLIILLAVGS DYNLLLVSRFQEEIGAGLKTGIIRSMGGTGGVVTSAGLVFAFTMMSMVASDLSSIGQAGSTIGLGLLFDT LIVRSLMTPSLAGLLGPWFWWPLRVRTGPTAEARPNGRRPYTQEGILNIATGPER
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. abscessus ATCC 19977 | MAB_4746 | - | - | 100% (965) | putative membrane protein, MmpL |
M. abscessus ATCC 19977 | MAB_2301 | - | 0.0 | 54.67% (953) | putative membrane protein, mmpL |
M. abscessus ATCC 19977 | MAB_1134c | - | 0.0 | 54.04% (940) | membrane protein MmpL |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0458c | mmpL4 | 0.0 | 57.58% (943) | transmembrane transport protein MmpL4 |
M. gilvum PYR-GCK | Mflv_3435 | - | 0.0 | 55.04% (952) | transport protein |
M. tuberculosis H37Rv | Rv0450c | mmpL4 | 0.0 | 57.69% (943) | transmembrane transport protein MmpL4 |
M. leprae Br4923 | MLBr_02378 | - | 0.0 | 54.86% (937) | hypothetical protein MLBr_02378 |
M. marinum M | MMAR_3048 | mmpL5_5 | 0.0 | 75.47% (962) | transmembrane transport protein, MmpL5_5 |
M. avium 104 | MAV_2510 | - | 0.0 | 55.40% (944) | MmpL4 protein |
M. smegmatis MC2 155 | MSMEG_3496 | - | 0.0 | 54.87% (935) | MmpL4 protein |
M. thermoresistible (build 8) | TH_3260 | - | 0.0 | 52.35% (936) | PUTATIVE MmpL4 protein |
M. ulcerans Agy99 | MUL_0757 | mmpL5 | 0.0 | 55.12% (938) | transmembrane transport protein, MmpL5 |
M. vanbaalenii PYR-1 | Mvan_3189 | - | 0.0 | 55.25% (952) | transport protein |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_3435|M.gilvum_PYR-GCK MSAPVSDARTDEFPAAHGPHRS------FIPRMIRLFAVPIILGWIALIV Mvan_3189|M.vanbaalenii_PYR-1 MSAPVSDARTDEFPAARQPHRP------FIPRMIRLFAVPIILGWIALIV TH_3260|M.thermoresistible__bu MTANPGHVRTDEAPTDRLDIKVSTHGPSFISTWIRRLSLPIIVGWIALIA MUL_0757|M.ulcerans_Agy99 MTATTTDTPTDVVPPAEHPPRP------FIPRMIRTFAVPLILGWVLLIA MAV_2510|M.avium_104 MSTTFDDTRTDAIPVV--KEPVR----EKIPRFIRAFAVPIIIGWIALIA MSMEG_3496|M.smegmatis_MC2_155 MSNPSHDAPTDAMGVSGPKHARP----GGIAKWIRVLAVPIILVWVAIIA Mb0458c|M.bovis_AF2122/97 MSTKFANDSNTNARPEK----------PFIARMIHAFAVPIILGWLAVCV Rv0450c|M.tuberculosis_H37Rv MSTKFANDSNTNARPEK----------PFIARMIHAFAVPIILGWLAVCV MLBr_02378|M.leprae_Br4923 MTVKCANDLDTHTKP------------PFVARMIHRFAVPIILVWLAIAV MAB_4746|M.abscessus_ATCC_1997 MSGESRVSAPAPERPA-------------FMRFVRRFAVPILTTWLFMTV MMAR_3048|M.marinum_M MSGKS-----GNDRPR-------------FMRMVRAFAIPIILIWLLLTI *: . :: :::*:: *: : Mflv_3435|M.gilvum_PYR-GCK VVNVTVPQLETVGEAQAVSMSPNDAPSMISMKKVGELFEEGDSDSSVMIV Mvan_3189|M.vanbaalenii_PYR-1 ILNVTVPQLEAVGEARAVSMSPNEAPSLISMKKVGELFREGDSDSSVMIV TH_3260|M.thermoresistible__bu LLNITVPQLEVVGEMRAVSMSPDEAPSMVAMKRVGELFDEGSSDSQVMIV MUL_0757|M.ulcerans_Agy99 VLNSVVPQLEVVGQMQAVSMSPDAAPSMISMKHIGKVFREGDSDSAAMIV MAV_2510|M.avium_104 VLNVVVPQLDEVGKMRSVEMTPDDAQSVVATKRMGAVFNEYKSNSSVMIV MSMEG_3496|M.smegmatis_MC2_155 VLNTVVPQLDVVGEMRSVSMSPDDAPSVIAMKRVGEVFEEFKSNSSVMIV Mb0458c|M.bovis_AF2122/97 VVTVFVPSLEAVGQERSVSLSPKDAPSFEAMGRIGMVFKEGDSDSFAMVI Rv0450c|M.tuberculosis_H37Rv VVTVFVPSLEAVGQERSVSLSPKDAPSFEAMGRIGMVFKEGDSDSFAMVI MLBr_02378|M.leprae_Br4923 TVSVFIPSLEDVGQERSVSLSPKDAPSYIAMQKMGQVFNEGNSDSVIMIV MAB_4746|M.abscessus_ATCC_1997 AVNVLVPPIESVAREHAVTMSPHDAPAMIAAKHIGQKYHESDSDSIAMIV MMAR_3048|M.marinum_M AVNVFVPQIEFVARDNAVTMSPQDAPAMIAAKRIGKTFHESDSDSIVMIV :. :* :: *.. .:* ::*. * : : ::* : * .*:* *:: Mflv_3435|M.gilvum_PYR-GCK FEGDQPLGDEAHAWYDELVDRLEADTAHVQSVQDFWSDPLTASGSQSNDG Mvan_3189|M.vanbaalenii_PYR-1 FEGDQPLGDEAHAWYDELVERLRADTKHVQSVQDFWSDPLTASGSQSNDG TH_3260|M.thermoresistible__bu LEGEEPLGADARAFYDELVKRLEADDAHVENVQDLWSDPLTATGVQSPDG MUL_0757|M.ulcerans_Agy99 LEGQEPLGAAAHKFYDKMITKLRADTKHVQSVQDFWGDPLTATGAQSGDG MAV_2510|M.avium_104 LEGQQPLGADAHAYYDEIVRRLNADTKHVEHVQDMWSDPLTGAGAQSNDG MSMEG_3496|M.smegmatis_MC2_155 LEGEQPLGDEAHKYYDEIVDKLEADPAHVEHVQDFWGDPLTASGAQSPDG Mb0458c|M.bovis_AF2122/97 IEGNQPLGDAAHKYYDGLVAQLRADKKHVQSVQDLWGDPLTAAGVQSNDG Rv0450c|M.tuberculosis_H37Rv IEGNQPLGDAAHKYYDGLVAQLRADKKHVQSVQDLWGDPLTAAGVQSNDG MLBr_02378|M.leprae_Br4923 LEGDKPLGDDAHRFYDGLIRKLRADK-HVQSVQDFWGDPLTAPGAQSNDG MAB_4746|M.abscessus_ATCC_1997 LESDDPLGERAHQYYDNLVLALQADTRHVQHVQNVWGDPLTASGVQSRDG MMAR_3048|M.marinum_M LESDKELGDAAHRYYDGLVQKLEADTEHVQHVHNLWADRITAAGVQSGDG :*.:. ** *: :** :: *.** **: *::.*.* :*..* ** ** Mflv_3435|M.gilvum_PYR-GCK KAAYVQVKLSGNQGEALANESVKAVQQTVSSLE---PPPGVRAFVTGPAA Mvan_3189|M.vanbaalenii_PYR-1 KAAYVQVKLAGNQGESLANESVQAAQEIVRSLE---PPPGVRAFVTGPAA TH_3260|M.thermoresistible__bu KSAYVQVKLAGNQGEALANESVETVREMIATVSEEMAPEGVQAFVTGGAA MUL_0757|M.ulcerans_Agy99 KAAYVQVKLAGNQGESLANESVEAVKTIVDSLQ---APPGVKVYVTGSAA MAV_2510|M.avium_104 KASYVQVYLAGNQGEALANESVESVQNIVKSVQ---APNGVKAYVTGPAA MSMEG_3496|M.smegmatis_MC2_155 LASYVQVYTRGNQGEALANESVEAVQDIVESVP---APPGVKAYVTGPAA Mb0458c|M.bovis_AF2122/97 KAAYVQLSLAGNQGTPLANESVEAVRSIVESTP---APPGIKAYVTGPSA Rv0450c|M.tuberculosis_H37Rv KAAYVQLSLAGNQGTPLANESVEAVRSIVESTP---APPGIKAYVTGPSA MLBr_02378|M.leprae_Br4923 KAAYVQLSLAGNQGELLAQESIDAVRKIVVQTP---APPGITAWVTGASA MAB_4746|M.abscessus_ATCC_1997 RAAYVQVNLAGDQGSTLGNKSVVAVREIVDNST---PPQGVTVYVTGPAA MMAR_3048|M.marinum_M KAAYVQLNIAGNQGSTLGNESVDAVRAIVDRSP---PPDGMRVYITGPAA ::***: *:** *.::*: :.: : .* *: .::** :* Mflv_3435|M.gilvum_PYR-GCK LAADQHIAGDRSMRLIEAATFTVIIVMLLLVYRSIVTVLITLVMVVMSLA Mvan_3189|M.vanbaalenii_PYR-1 LAADQHIASDRSVRVIELVTFAVIIVMLLLVYRSIVTVLLTLVMVVLSLA TH_3260|M.thermoresistible__bu MSADQQEAGDSSLRVIEALTFLVITTMLLFVYRSVITVLIALFMVLIGLL MUL_0757|M.ulcerans_Agy99 LVADQQLAGDRSLQLIEMVTFTVIIVMLLLVYRSIITAAIMLTMVVLGLL MAV_2510|M.avium_104 LSADQHTAGDRSLQLITAATFTVIIGMLLLVYRSVITVLLTLVMVVLELS MSMEG_3496|M.smegmatis_MC2_155 LSADQHVASDRSVRVIEALTFAVIITMLLLVYRSIVTVILTLVMVVLSLS Mb0458c|M.bovis_AF2122/97 LAADMHHSGDRSMARITMVTVAVIFIMLLLVYRSIITVVLLLITVGVELT Rv0450c|M.tuberculosis_H37Rv LAADMHHSGDRSMARITMVTVAVIFIMLLLVYRSIITVVLLLITVGVELT MLBr_02378|M.leprae_Br4923 LIADMHHSGDKSMIRITATSVIVILVTLLLVYRSFITVILLLFTVGIESA MAB_4746|M.abscessus_ATCC_1997 LTTDMNEAADKSMLIMMGVTGAVIMIMLLITYRSVSTMLLVLVMVGFEMG MMAR_3048|M.marinum_M LTTDMNEAADKSMFKMMGVTGVVIMIMLFIVYRSVSTVLLVLAMVGFEMG : :* : :.* *: : : ** *::.***. * : * * . Mflv_3435|M.gilvum_PYR-GCK TARGVVAFLGHHEIIGLSTFATNLLVTLAIAAATDYAIFLIGRYQEARTA Mvan_3189|M.vanbaalenii_PYR-1 TARGVVAFLGWHEIIGLSLFATNLLVTLAIAAATDYAIFLIGRYQEARTN TH_3260|M.thermoresistible__bu TTRGVVAFLGYHNIIGLSTFATSLLVTLAIAIAVDYAIFLIGRYQEARSV MUL_0757|M.ulcerans_Agy99 ATRGGVAFLGYHRIIGLSTFATNLLVVLAIAAATDYAIFLIGRYQEARGL MAV_2510|M.avium_104 AARGMVAFLGYYKIIGLSTFATNLLVTLAIAAATDYAIFLIGRYQEARAV MSMEG_3496|M.smegmatis_MC2_155 AARGMIAFLGYHEIIGLSVFATNLLTTLAIAAATDYAIFLIGRYQEARSV Mb0458c|M.bovis_AF2122/97 AARGVVAVLGHSGAIGLTTFAVSLLTSLAIAAGTDYGIFIIGRYQEARQA Rv0450c|M.tuberculosis_H37Rv AARGVVAVLGHSGAIGLTTFAVSLLTSLAIAAGTDYGIFIIGRYQEARQA MLBr_02378|M.leprae_Br4923 VARGVVALLGHTGLIGLSTFAVNLLTSLAIAAGTDYGIFITGRYQEARQA MAB_4746|M.abscessus_ATCC_1997 TARGIVAILGNYDLLGFSTFVVAMLSSLAIAAGTDYAIFLIGRYQEARQV MMAR_3048|M.marinum_M TARGVIALLGHHHLLGFSTFVVAMLSSLAIAAGTDYAIFLIGRYQEARQA .:** :*.** :*:: *.. :* **** ..**.**: ******* Mflv_3435|M.gilvum_PYR-GCK GEDKETAYYTMFHGTAHVVLGSGLTIAGATFCLSFTRLPYFQTMGVPLAI Mvan_3189|M.vanbaalenii_PYR-1 GEDKESAYYTMFHGTAHVVLGSGLTIAGATYCLSFTRLPYFQTLGVPLAI TH_3260|M.thermoresistible__bu GADRATAYHTMFGGTAHVILASGLTIAGATFCLSFTRLPYFQSLGPPLAI MUL_0757|M.ulcerans_Agy99 GQDRESAYYTMFGGTAHVVLGSGLTIAGATFCLSFTRLPYFQTLGVPLAI MAV_2510|M.avium_104 GESREDAYYTMYKGTAHVVAGSGMTIAGATFCLHFTNLPYFQTLGIPLAI MSMEG_3496|M.smegmatis_MC2_155 GEDREQSYYTMFHSTAHVVLGSGMTIAGATLCLHFTRMPYFQSLGIPLAI Mb0458c|M.bovis_AF2122/97 GEDKEAAYYTMYRGTAHVILGSGLTITGATFCLSFARMPYFQTLGIPCAV Rv0450c|M.tuberculosis_H37Rv GEDKEAAYYTMYRGTAHVILGSGLTIAGATFCLSFARMPYFQTLGIPCAV MLBr_02378|M.leprae_Br4923 NENKEAAFYTMYRGTFHVILGSGLTISGATFCLSFARMPYFQTLGVPCAV MAB_4746|M.abscessus_ATCC_1997 GQDRENAYYTMFRGTFHIILGSGLTIAGATLCLHLARLSYFKALGIPSAL MMAR_3048|M.marinum_M GEDRETAYYSMFRGTYHVILGSGLTIAGATFCLHLARLSYFKALGIPSAL . .: ::::*: .* *:: .**:**:*** ** ::.:.**:::* * *: Mflv_3435|M.gilvum_PYR-GCK GMFVVVMAGVVLMVACISVATRFGKLLEPKRAMRIRGWRKIGAAIVRWPG Mvan_3189|M.vanbaalenii_PYR-1 GMFVVVMAGVILMVAMISVATRFGKLLEPKRAMRIRGWRKIGAAVVRWPG TH_3260|M.thermoresistible__bu GMIVLIVTSLTMGPAIITVATRFG-LLEPKRAARVRFWRKVGASVVRWPG MUL_0757|M.ulcerans_Agy99 GMVIVVATALTLGPALIAVMSRFGKLLEPKRMARVRGWRKIGAAIVRWPG MAV_2510|M.avium_104 GMVVVVAAALTLGPAVISVASRFRQTLEPRRTQRIRGWRKVGTVVVRWPG MSMEG_3496|M.smegmatis_MC2_155 GMSVVVLASLTMGAAIISVASRFGKTFEPKRAMRTRGWRKLGAAVVRWPA Mb0458c|M.bovis_AF2122/97 GMLVAVAVALTLGPAVLHVGSRFG-LFDPKRLLKVRGWRRVGTVVVRWPL Rv0450c|M.tuberculosis_H37Rv GMLVAVAVALTLGPAVLHVGSRFG-LFDPKRLLKVRGWRRVGTVVVRWPL MLBr_02378|M.leprae_Br4923 GMLIAVAVALTLGPAVLTVGSRFG-LFEPKRLIKVRGWRRIGTVVVRWPL MAB_4746|M.abscessus_ATCC_1997 GLLVVVVGALTAAPAVVVVAGRFG-LLDPKRPVNVRRWRRIGTATVRWPG MMAR_3048|M.marinum_M GLLVVIAGALTAAPAIVAVATRFG-LLDPRRMIKVRGWRRIGTATVRWPG *: : : .: * : * ** ::*:* . * **::*: **** Mflv_3435|M.gilvum_PYR-GCK PILVATMAITLVGLLALPGYKTNYNDRDYLPADLPANQGYAVADEHFDQA Mvan_3189|M.vanbaalenii_PYR-1 PILVATLAITLVGLLALPGYKTNYNDRTYLPADLPANEGYAVADRHFDQA TH_3260|M.thermoresistible__bu PIMVTTVAVTLVGLLALPGYRTNYNDRNYLPASFPSNAGYEAAERHFDPA MUL_0757|M.ulcerans_Agy99 PILIGAVALALVGLLTLPGYKTNYNDRNYLPADLPANEGYSAAERHFSQA MAV_2510|M.avium_104 PILVLTIGVALVGLLTLPGYRTNYNDRNYLPTDLPANEGYAAADRHFSQA MSMEG_3496|M.smegmatis_MC2_155 PILVTTIALSVVGLLALPGYQTNYNDRRYLPQDLPANTGYAAADRHFSQA Mb0458c|M.bovis_AF2122/97 PVLVATCAIALVGLLALPGYKTSYNDRDYLPDFIPANQGYAAADRHFSQA Rv0450c|M.tuberculosis_H37Rv PVLVATCAIALVGLLALPGYKTSYNDRDYLPDFIPANQGYAAADRHFSQA MLBr_02378|M.leprae_Br4923 PILITTCAIAMVGLLALPGYRTNYKDRAYLPASIPANQGFAAADRHFPQA MAB_4746|M.abscessus_ATCC_1997 AVFAASSAIALVGIAIMPTMKVSYNDRFYIPEDLPSNIGYTAAERHFSSA MMAR_3048|M.marinum_M PVFVASLLIALVGMMVVPGMKISYNDRYYIPRNLPSNVGYVAAEQHFSAA .:: : :::**: :* : .*:** *:* :*:* *: .*:.** * Mflv_3435|M.gilvum_PYR-GCK RMNPELLMIESDHDLRNSADFLVIDKIAKALFRVEGIARVQAITRPDGKP Mvan_3189|M.vanbaalenii_PYR-1 RMNPELLMIESDHDLRNSADFLVIDKIAKAIFKVEGIARVQAITRPDGKP TH_3260|M.thermoresistible__bu RLNPELLLIESDHDLRNPADFLVIEKIAKAVFQVEGISRVQGITRPEGTP MUL_0757|M.ulcerans_Agy99 RMNPEVLMVESDHDMRNSSDFLVINKIAKAIFGVEGISRVQAITRPDGKP MAV_2510|M.avium_104 RMNPEVLMIESDHDLRNSADFLVIDKIAKTVFRVPGIGRVQAITRPQGTP MSMEG_3496|M.smegmatis_MC2_155 RMNPELLMIESDHDLRNSADFLVVDRIAKRVFQVPGISRVQAITRPQGTP Mb0458c|M.bovis_AF2122/97 RMKPEILMIESDHDMRNPADFLVLDKLAKGIFRVPGISRVQAITRPEGTT Rv0450c|M.tuberculosis_H37Rv RMKPEILMIESDHDMRNPADFLVLDKLAKGIFRVPGISRVQAITRPEGTT MLBr_02378|M.leprae_Br4923 RMKPEILMIESDHDMRNPADFLILDKLARGIFRVPGISRVQAITRPDGTA MAB_4746|M.abscessus_ATCC_1997 TMNPDILMIESDHDMRNTGDMIILDRIAKEVFRSPGIAMVQSITRPLGGP MMAR_3048|M.marinum_M RLNPDILMIEGDHDMRNSSDMILLDRIAKEVFRAPGIARVQSITRPLGSP ::*::*::*.***:**..*:::::::*: :* **. **.**** * . Mflv_3435|M.gilvum_PYR-GCK IKHTSIPFQMSMQGTTQRLNEKYMQDRMADMLVQADEMANTIKTMEKMSG Mvan_3189|M.vanbaalenii_PYR-1 IKHTSIPFQMSMQGTTQRLNEKYMQDRMADMLVQADEMANTIATMEKMSN TH_3260|M.thermoresistible__bu IEHSSIPFMISQQGTLQILNQQYMQDRMADMLVQADEMQLMIDTMDKMIA MUL_0757|M.ulcerans_Agy99 IEHTSIPFLISMQGTSQKLTEKYNQDLTTSMLQQVNDIQTNIDQMERMHD MAV_2510|M.avium_104 IEHTSIPFQISMQGVTQQMNQKYQQDQMADMLHQADMMQTTIDSMEKMQS MSMEG_3496|M.smegmatis_MC2_155 IEHTSIPFQISMSGTTQMMNMKYMQDRMADMLVMADEMQKSVDTMEEMLK Mb0458c|M.bovis_AF2122/97 MDHTSIPFQISMQNAGQLQTIKYQRDRANDMLKQADEMATTIAVLTRMHS Rv0450c|M.tuberculosis_H37Rv MDHTSIPFQISMQNAGQLQTIKYQRDRANDMLKQADEMATTIAVLTRMHS MLBr_02378|M.leprae_Br4923 MDHTSIPFQISMQNAGQVQTMKYQKDRMNDLLRQAENMAETIASMRRMHQ MAB_4746|M.abscessus_ATCC_1997 IEHTSIPFQISAQSIPIQQNLQFMKDRAADMLSMSKDLDALIGAMERMQS MMAR_3048|M.marinum_M IEHSSIPFQVSMQALPIQQNLKFMKERTADMLKMSDDLGAMIASMERMQG :.*:**** :* . . :: :: .:* . : : : .* Mflv_3435|M.gilvum_PYR-GCK LTAQMADITHSMVTKMEGMVVDIEDLRDSIANFDDFFRPIRNYFYWEPHC Mvan_3189|M.vanbaalenii_PYR-1 LTAQMADITHSMVSKMENMLTDIEDLRDSIANFDDFFRPIRNYFYWEPHC TH_3260|M.thermoresistible__bu LMEEMVETTDNMVRDMDEMAAHVAEMRDSISEFDDFFRPIRNYFYWEPHC MUL_0757|M.ulcerans_Agy99 LTQQMADVTHQMVIQMKGMVVDVEELRNHIADFDDFFRPIRSYFYWEKHC MAV_2510|M.avium_104 ITVQMSNDMHVMVQKMHDMTIDINDLRNKMADFEDFFRPMRSYFYWEKHC MSMEG_3496|M.smegmatis_MC2_155 ITREMSDTTHSMVGKMHGMVEDIKELRDHIADFDDFLRPIRNYFYWEPHC Mb0458c|M.bovis_AF2122/97 LMAEMASTTHRMVGDTEEMKEITEELRDHVADFDDFWRPIRSYFYWEKHC Rv0450c|M.tuberculosis_H37Rv LMAEMASTTHRMVGDTEEMKEITEELRDHVADFDDFWRPIRSYFYWEKHC MLBr_02378|M.leprae_Br4923 LMALLTENTHHILNDTVEMQKTTSKLRDEIANFDDFWRPIRSYFYWERHC MAB_4746|M.abscessus_ATCC_1997 LLGQMSSATHRMSANMTDAKTTLEEIRDHLADFDDVVRPLRNYFYWEQHC MMAR_3048|M.marinum_M LLGQMSGTTHRMVGDMGEMRVTLNEMRDHLADFDDFARPFRGYLYWEQHC : : . : . .:*: :::*:*. **:*.*:*** ** Mflv_3435|M.gilvum_PYR-GCK YNIPVCWALRSVFDTLDGINIMTDDFKAIIPDMKRLDTLMPQMVALMPEM Mvan_3189|M.vanbaalenii_PYR-1 YNIPVCWALRSVFDTLDGINVMTDDFREILPDMKRLDSLMPQMVALMPEM TH_3260|M.thermoresistible__bu YNIPVCWAMRSVFDTLDGINTMTDDIQNMLPHMHRLNDLMPQMLTLLPTT MUL_0757|M.ulcerans_Agy99 FDIPVCWSLRSVFDTLDGVDLMTEDINNLLPLMERLDTLMPQMTAMMPEM MAV_2510|M.avium_104 YDIPVCWSLRSVFDALDGIDTMTDDIQSLLPIMDHLDTLMPQMVALMPSM MSMEG_3496|M.smegmatis_MC2_155 DSIPVCQSIRSIFDTLDGIDVMTDDIQRLMPDMDRLDELMPQMLTIMPPM Mb0458c|M.bovis_AF2122/97 YGIPICWSFRSIFDALDGIDKLSEQIGVLLGDLREMDRLMPQMVAQIPPQ Rv0450c|M.tuberculosis_H37Rv YGIPICWSFRSIFDALDGIDKLSEQIGVLLGDLREMDRLMPQMVAQIPPQ MLBr_02378|M.leprae_Br4923 FNIPICWSFRSIFDALDGVDQIDERLNSIVGDIKNMDLLMPQMLEQFPPM MAB_4746|M.abscessus_ATCC_1997 FDLPACSAIRSVFDALDGVDAFSDKMRALTTDIGNVDAVIPQMAAQLPPI MMAR_3048|M.marinum_M FNIPVCWASRSVFDAIDGVDKFSENMDALIGDMNDVDSILPRMQAEFPSM .:* * : **:**::**:: : : : : : :: ::*:* :* Mflv_3435|M.gilvum_PYR-GCK IETMKTMRTMMLTMYQSQKGQQDQMAAMSEDADAMGEAFDDSMNDDSFYL Mvan_3189|M.vanbaalenii_PYR-1 IETMKTMRTMMLTMYQSQKGQQDQMAAMSEDADAMGEAFDDSMNDDSFYL TH_3260|M.thermoresistible__bu VATMKTMRSMLLTMQATNAGLQDQMAEMQENANAMGEAFDQARNDDSFYL MUL_0757|M.ulcerans_Agy99 IQTMKSMKAQMLSMHSTQQGLQDQMAAMQEDSSAMGEAFDSSRNDDSFYL MAV_2510|M.avium_104 IENMKAMKTTMLTMYSTQKGLQDQQNEAQKNSNAMGKAFDASKNDDSFYL MSMEG_3496|M.smegmatis_MC2_155 IESMKTMKTMMLTTQATMGGLQDQMEAAMENQTAMGQAFDASKNDDSFYL Mb0458c|M.bovis_AF2122/97 IEAMENMRTMILTMHSTMTGIFDQMLEMSDNATAMGKAFDAAKNDDSFYL Rv0450c|M.tuberculosis_H37Rv IEAMENMRTMILTMHSTMTGIFDQMLEMSDNATAMGKAFDAAKNDDSFYL MLBr_02378|M.leprae_Br4923 IESMESMRTIMLTMHSTMSGIFDQMNELSDNANTMGKAFDTAKNDDSFYL MAB_4746|M.abscessus_ATCC_1997 IAVARSMQDTLLTMHSSFSNLITQMAHMTDTASAMGQAFDASRSGDYFYL MMAR_3048|M.marinum_M IAVATSMRGTLLTLHSSFSGLVTQMSRMTDTASAMGQAFDASKADDYFYL : *: :*: : . * . :**:*** : .* *** Mflv_3435|M.gilvum_PYR-GCK PPEIFENADFQRGLEQFLSPDGHAVRFIISHEGDPLSPEGVAKIDKIKTA Mvan_3189|M.vanbaalenii_PYR-1 PPEIFENKDFQRGLEQFLSPDGHAVRFIISHEGDPLSPEGVAKIDKIKTA TH_3260|M.thermoresistible__bu PPEAFDNPDFQRGLEQFLSPDGHAVRFIISHQGDPMTPEGLAKIEPIKKA MUL_0757|M.ulcerans_Agy99 PPEVFNNPDFKRGLEQFLSPDGHAVRFIISHEGDPMSQAGINHIDKIKTA MAV_2510|M.avium_104 PPETFNNKEFKKGMKNFISPDGHAVRFIISHDGDPMTQEGISHIGAIKKA MSMEG_3496|M.smegmatis_MC2_155 PPETFENPDFKRGMKMFLSPDGHAVRFIISHEGDPMSPEGIKHIDAIKQA Mb0458c|M.bovis_AF2122/97 PPEVFKNKDFQRAMKSFLSSDGHAARFIILHRGDPQSPEGIKSIDAIRTA Rv0450c|M.tuberculosis_H37Rv PPEVFKNKDFQRAMKSFLSSDGHAARFIILHRGDPQSPEGIKSIDAIRTA MLBr_02378|M.leprae_Br4923 PPEVFKNTDFKRAMKSFLSSDGHAARFIILHRGDPASVAGIASINAIRTA MAB_4746|M.abscessus_ATCC_1997 PPEAFQNPDFQRGLKLFLSPDGTAARFIITHDRDPATPAGISTVTSELEA MMAR_3048|M.marinum_M PPEAFDNPDFQRGLKLFLSSDGKAARFIITHDSDPATPKGIAAVKPELNA *** *.* :*::.:: *:*.** *.**** * ** : *: : * Mflv_3435|M.gilvum_PYR-GCK AKEAVKGTPLEGSKIYLGGTAAVFKDMQDGNNYDLLIAGIAALGLIFIIM Mvan_3189|M.vanbaalenii_PYR-1 AKEAIKGTPLEGSKIYLGGTAATFKDMQDGNNYDLLIAGISALGLIFIIM TH_3260|M.thermoresistible__bu AVEAIKGTPLEGSRVYLGGTAAVFKDMSDGTKYDLIIAAIAAVCLIFIIM MUL_0757|M.ulcerans_Agy99 AKEAIKGTPLEGSTIYLGGTVAMFKDLSDGNTFDLMIAGISALCLIFIIM MAV_2510|M.avium_104 AYEALKGTPLEGSKIYLAGTASIYKDLSDGNNYDLLIAGISSLCLIFIIM MSMEG_3496|M.smegmatis_MC2_155 AKEAIKGTPLEGSKIYLGGTAATFKDLQEGANYDLIIAGIAALCLIFIIM Mb0458c|M.bovis_AF2122/97 AEESLKGTPLEDAKIYLAGTAAVFHDISEGAQWDLLIAAISSLCLIFIIM Rv0450c|M.tuberculosis_H37Rv AEESLKGTPLEDAKIYLAGTAAVFHDISEGAQWDLLIAAISSLCLIFIIM MLBr_02378|M.leprae_Br4923 AEEALKGTPLEDTKIYLAGTAAVFKDIDEGANWDLVIAGISSLCLIFIIM MAB_4746|M.abscessus_ATCC_1997 AHQAVKGTALTDAKFYLAGTAAIYRDIQSGSRYDLLIVGIAAVTLIFAVM MMAR_3048|M.marinum_M ARQAVKGTPLADAKFYLTGTAAIYNDIQTGSKYDILIVGIAALTLIFVVM * :::***.* .: .** **.: :.*:. * :*::*..*::: *** :* Mflv_3435|M.gilvum_PYR-GCK LILTRAVVAAAVIVGTVVLSLAASFGLSVLFWQHILGQPLHWMVLAMAVI Mvan_3189|M.vanbaalenii_PYR-1 LILTRAIVAAAVIVGTVVLSLAASFGLSVLFWQHILGTELHWMVLAMAVI TH_3260|M.thermoresistible__bu LILTRAVVAAAVIVGTVTLSLAASFGVSVLIWQYIVGLEMHWMVFPMALI MUL_0757|M.ulcerans_Agy99 LIITRSVVAAAVIVGTVVLSLGASFGLSVLIWQHVLGIELHWLVLAMAVI MAV_2510|M.avium_104 LIITRGVVASAVIVGTVLLSLGASFGLSVLIWQHLIGIELHWMVLAMSVI MSMEG_3496|M.smegmatis_MC2_155 LIITRAVVASAVIVGTVVISLGASFGLSVLIWQHIIGLELHWMVLAMAVI Mb0458c|M.bovis_AF2122/97 LIITRAFIAAAVIVGTVALSLGASFGLSVLLWQHILAIHLHWLVLAMSVI Rv0450c|M.tuberculosis_H37Rv LIITRAFIAAAVIVGTVALSLGASFGLSVLLWQHILAIHLHWLVLAMSVI MLBr_02378|M.leprae_Br4923 LIITRAFVAAAVIVGTVALSLGASFGLSVLLWQHILGIELHYLVLAMSVI MAB_4746|M.abscessus_ATCC_1997 MIITRAFVASLAIVGTVLLSLGAAFGISVLVWQHIFGLELNWIAPVFGLI MMAR_3048|M.marinum_M VIITRALVASLVIVGTVLLSLGAAFGLSVLVWQHILGLDLNWIAPVFGVI :*:**..:*: .***** :**.*:**:***.**::.. ::::. :.:* Mflv_3435|M.gilvum_PYR-GCK ILLAVGADYNLLLVSRLKEEIHAGIGTGIIRAMGGSGSVVTAAGLVFALT Mvan_3189|M.vanbaalenii_PYR-1 VLLAVGADYNLLLVSRLKEEIHAGIGTGIIRAMGGSGSVVTAAGLVFALT TH_3260|M.thermoresistible__bu ILLAVGADYNLLVVARLREEIPAGLNTGMIRAMGGSGSVVTAAGLVFGLT MUL_0757|M.ulcerans_Agy99 ILLAVGADYNLLLVARLKEEIHAGINTGIIRAMGGSGSVVTAAGLVFAFT MAV_2510|M.avium_104 ILLAVGADYNLLLVARFKEEIHAGLNTGIIRSMGGTGSVVTSAGLVFAFT MSMEG_3496|M.smegmatis_MC2_155 VLLAVGADYNLLLVSRIKEEIHAGLNTGIIRSMGGTGSVVTSAGLVFAFT Mb0458c|M.bovis_AF2122/97 VLLAVGSDYNLLLVSRFKQEIGAGLKTGIIRSMGGTGKVVTNAGLVFAVT Rv0450c|M.tuberculosis_H37Rv VLLAVGSDYNLLLVSRFKQEIGAGLKTGIIRSMGGTGKVVTNAGLVFAVT MLBr_02378|M.leprae_Br4923 VLLAVGSDYNLLLVSRFKQEIQAGLKTGIIRSMGGTGKVVTNAGLVFAFT MAB_4746|M.abscessus_ATCC_1997 ILLAVGSDYNLLLVSRFQEEIGAGLKTGIIRSMGGTGGVVTSAGLVFAFT MMAR_3048|M.marinum_M ILLAVGSDYNLLLVSRFQEEIGAGLKTGIIRSMGETGGVVTAAGLVFAFT :*****:*****:*:*:::** **: **:**:** :* *** *****..* Mflv_3435|M.gilvum_PYR-GCK MMSMSVSELTVIGQVGTTIGLGLLFDTLVIRAFMTPSIAALLGPWFWWPQ Mvan_3189|M.vanbaalenii_PYR-1 MMSMAVSELTVIGQVGTTIGLGLLFDTLVIRAFMTPSIAALLGPWFWWPQ TH_3260|M.thermoresistible__bu MMVMVVSDLTVMGQVGTTIGLGLLFDTFVVRSFMMPSIATLLGRWFWWPQ MUL_0757|M.ulcerans_Agy99 MMSFAVSELTVMAQVGTTIGMGLLFDTLIVRSFMTPSIAALLGKWFWWPQ MAV_2510|M.avium_104 MMTMAVSELTVIGQVGTTIGLGLLFDTLIVRSLMTPSIAALLGKWFWWPQ MSMEG_3496|M.smegmatis_MC2_155 MMSMAVSELAVIAQVGTTIGLGLLFDTLVIRSFMTPSIAALMGKWFWWPQ Mb0458c|M.bovis_AF2122/97 MASMAVSDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSIAALLGRWFWWPL Rv0450c|M.tuberculosis_H37Rv MASMAVSDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSIAALLGRWFWWPL MLBr_02378|M.leprae_Br4923 MASMVVSDLRVIGQVGTTIGLGLLFDTLIVRSFMMPSIAALLGRWFWWPQ MAB_4746|M.abscessus_ATCC_1997 MMSMVASDLSSIGQAGSTIGLGLLFDTLIVRSLMTPSLAGLLGPWFWWPL MMAR_3048|M.marinum_M MLSMVASDLRSIGQAGSTIGLGLLFDTLIVRSLMTPSVAALLGRWFWWPL * : .*:* :.*.*:***:******:::*::* **:* *:* ***** Mflv_3435|M.gilvum_PYR-GCK RVRTRPVPAPWPRSGGLQSDPSEGVRA----------------------- Mvan_3189|M.vanbaalenii_PYR-1 RVRTRPVPAPWPRPGGLQSDPSEGVKV----------------------- TH_3260|M.thermoresistible__bu FVRKRPVPQPWPSVPPRGPATTDRVSV----------------------- MUL_0757|M.ulcerans_Agy99 VVRQRPAPQPWPTPAPTPPPATTSV------------------------- MAV_2510|M.avium_104 RVRQRPVPSPWPKPAAQEREVLADA------------------------- MSMEG_3496|M.smegmatis_MC2_155 RVRQRPLPAPWPQPVQRDPEDALNRV------------------------ Mb0458c|M.bovis_AF2122/97 RVRSRPARTPTVPSETQPAGRPLAMSSDRLG------------------- Rv0450c|M.tuberculosis_H37Rv RVRSRPARTPTVPSETQPAGRPLAMSSDRLG------------------- MLBr_02378|M.leprae_Br4923 QGRTRPLLTVAAPVGLPPD-RSLVYSD----------------------- MAB_4746|M.abscessus_ATCC_1997 RVRTGPT-AEARPNGRRPYTQEGIL----NIAT--------GPER----- MMAR_3048|M.marinum_M RVRPRPASYMLRPFGPRRLVRSLLLGEPTDVATSQPAGYGGSPERSNGDP * * Mflv_3435|M.gilvum_PYR-GCK -------------------- Mvan_3189|M.vanbaalenii_PYR-1 -------------------- TH_3260|M.thermoresistible__bu -------------------- MUL_0757|M.ulcerans_Agy99 -------------------- MAV_2510|M.avium_104 -------------------- MSMEG_3496|M.smegmatis_MC2_155 -------------------- Mb0458c|M.bovis_AF2122/97 -------------------- Rv0450c|M.tuberculosis_H37Rv -------------------- MLBr_02378|M.leprae_Br4923 -------------------- MAB_4746|M.abscessus_ATCC_1997 -------------------- MMAR_3048|M.marinum_M ATVPAAVPAPETGGADGSAR