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VGANGDVALSRIGATRPALSAWRFVTVFGVVGLLADVVYEGARSITGPLLASLGATGLVVGVVTGVGEAA ALGLRLVSGPLADRSRRFWAWTIAGYTLTVVTVPLLGIAGALWVACALVIAERVGKAVRGPAKDTLLSHA ASVTGRGRGFAVHEALDQVGAMIGPLTVAGMLAITGNAYAPALGVLTLPGGAALALLLWLQRRVPRPESY EDCPVVLGNPSAPRPWALPAQFWLYCGFTAITMLGFGTFGLLSFHMVSHGVLAAAMVPVVYAAAMAADAL TALASGFSYDRYGAKTLAVLPILSILVVLFAFTDNVTMVVIGTLVWGAAVGIQESTLRGVVADLVASPRR ASAYGVFAAGLGAATAGGGALIGWLYDISIGTLVVVVIALELMALVMMFAIRLPRVAPS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2265 | - | - | 100% (409) | Possible conserved integral membrane protein |
| M. tuberculosis H37Rv | Rv0842 | - | 3e-10 | 31.58% (152) | integral membrane protein |
| M. tuberculosis H37Rv | Rv2456c | - | 2e-07 | 21.82% (362) | integral membrane transport protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2288 | - | 0.0 | 100.00% (409) | integral membrane protein |
| M. gilvum PYR-GCK | Mflv_1475 | - | 1e-08 | 27.27% (198) | major facilitator transporter |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4615 | - | 1e-148 | 68.25% (378) | major facilitator transporter |
| M. marinum M | MMAR_0136 | - | 2e-22 | 26.04% (361) | intergral membrane protein |
| M. avium 104 | MAV_3974 | - | 2e-09 | 24.92% (333) | permease of the major facilitator superfamily protein |
| M. smegmatis MC2 155 | MSMEG_6390 | - | 2e-06 | 22.25% (346) | transporter, major facilitator family protein |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_4961 | - | 7e-24 | 26.59% (361) | intergral membrane protein |
| M. vanbaalenii PYR-1 | Mvan_2778 | - | 1e-137 | 64.54% (392) | major facilitator superfamily transporter |
CLUSTAL 2.0.9 multiple sequence alignment
Rv2265|M.tuberculosis_H37Rv MGANGDVALSRIGATRPALSAWRFVTVFGVVGLLADVVYEGARSITGPLL
Mb2288|M.bovis_AF2122/97 MGANGDVALSRIGATRPALSAWRFVTVFGVVGLLADVVYEGARSITGPLL
MAB_4615|M.abscessus_ATCC_1997 --------------MPQRLSAWRFVTTFGVISMLADIVYEGARSITGPLL
Mvan_2778|M.vanbaalenii_PYR-1 ----------MTGTPGVGLSAWRFVTTFGVVSLLADIVYEGARSITGPLL
MMAR_0136|M.marinum_M -----------MTSGSAPQWLTRNLRVLSLVSLLQDAASELLYPLLPIYL
MUL_4961|M.ulcerans_Agy99 -----------MTSGSAPQWLTRNLRVLSLVSLLQDAASELLYPLLPIYL
Mflv_1475|M.gilvum_PYR-GCK ---------------MAPLSPTAQRAPLLAAGFTTAFGAHAVAGTLGTTT
MAV_3974|M.avium_104 ---------------------------------MVALGYGVISPALPTFA
MSMEG_6390|M.smegmatis_MC2_155 ---------MRRYLAATFSALTIRDYRRYALGQTISVSGTWMQKLTQAWL
Rv2265|M.tuberculosis_H37Rv AS-LGATGLVVGVVTGVGEAAALGLRLVSGPLADRSRRF----WAWTIAG
Mb2288|M.bovis_AF2122/97 AS-LGATGLVVGVVTGVGEAAALGLRLVSGPLADRSRRF----WAWTIAG
MAB_4615|M.abscessus_ATCC_1997 AS-LGASALVVGVVTGIGEAAALALRLVSGPLTDRTRKF----WAWTISG
Mvan_2778|M.vanbaalenii_PYR-1 AS-LGATAVVVGVVTGVGEAAALILRMVSGPLADRTGRF----WTWTIGG
MMAR_0136|M.marinum_M TTVLGAPPSVVGAVEGAAEGAASLTKVVSGPLGDRFAR-----RPLIASG
MUL_4961|M.ulcerans_Agy99 ATVLGAPPSVVGAVEGAAEGAASLTKIVSGPLGDRFAR-----RPLIASG
Mflv_1475|M.gilvum_PYR-GCK TG-TAASLLTLGAMLAIYDGAEVILKPLFGTLADRIGA-----RTVLIAG
MAV_3974|M.avium_104 RS-FGVSIKAVTFLVTVFSLSRLCFAPISGLLTERLGE-----RRIYIGG
MSMEG_6390|M.smegmatis_MC2_155 VLELTDSPLLLGVTVAGQQLPTLLFTTLAGVLADRYSKRTILLWTALGGM
. : . . : * * :* .
Rv2265|M.tuberculosis_H37Rv YTLTVVTVPLLGIAGALWVACALVIAERVGKAVRGPAKDTLLSHAASVTG
Mb2288|M.bovis_AF2122/97 YTLTVVTVPLLGIAGALWVACALVIAERVGKAVRGPAKDTLLSHAASVTG
MAB_4615|M.abscessus_ATCC_1997 YALTVVTVPFLGVSSVLWIAATLVIAERVGKAVRSPAKDTLLSHATAVTG
Mvan_2778|M.vanbaalenii_PYR-1 YFLTVVTVPFLGAVGVLWAAAALIIAERVGKAVRSPAKDTLLSHATAVTG
MMAR_0136|M.marinum_M YGMAALGKLIVAAAGAWPGVLAGRVVDRLGKGLRGAPRDALLVDGVEPAQ
MUL_4961|M.ulcerans_Agy99 YGMAALGKLIVAAAGAWPGVLAGRVVDRLGKGLRGAPRDALLVDGVDPAQ
Mflv_1475|M.gilvum_PYR-GCK LAVFAVASLSFAVADETAWLWAARLGQGIGAAAFSPAASALVARLAPASG
MAV_3974|M.avium_104 LLIVAVSTAACAFSQAYWQLMLCRVFSGVGSTMFYVSALGLMIHISPADA
MSMEG_6390|M.smegmatis_MC2_155 LPALVLGVLVWIDVVNIWIVLAAAVAQGFADAVDKPARLTFVNDIATPET
.: : . .. . ::
Rv2265|M.tuberculosis_H37Rv RGRGFAVHEALDQVGAMIGPLTVAGMLAITGNAYAPALGVLTLPGGAALA
Mb2288|M.bovis_AF2122/97 RGRGFAVHEALDQVGAMIGPLTVAGMLAITGNAYAPALGVLTLPGGAALA
MAB_4615|M.abscessus_ATCC_1997 RGKGFAVHEAMDQIGAITGPLLVAGMLALTHVNYLPTFAILALPGGATLL
Mvan_2778|M.vanbaalenii_PYR-1 RGRGFAVHEAMDQIGAVAGPLAVAAMLVVFGGDYAPTLALLAVPGVGVLA
MMAR_0136|M.marinum_M RGRAFGFHRTMDTLGAVIGPLLGLAGYELFDHQIGPVLYLAVIPAVLSVL
MUL_4961|M.ulcerans_Agy99 RGRAFGFHRTMDTLGAVIGPLLGLAGYELFDHQIGPVLYLAVIPAMLSVL
Mflv_1475|M.gilvum_PYR-GCK QGRAFGTYGSYKSVGYTLGPLIGGAIVTFGG-----LQALFAVMAALAAA
MAV_3974|M.avium_104 RGRIAGLFTTSFMVGAVGGPAVGG--LAAGWGLTAPFVVYGVAMLGVALV
MSMEG_6390|M.smegmatis_MC2_155 LANAVTLNSIIQNSGKIAGPAVAGVLISAVGVSASFFLNAASYLPVVIAL
.. * **
Rv2265|M.tuberculosis_H37Rv LLLWLQRRVPRPESY--EDCPVVLGNPSAPRPWALPAQFWLYCGFTAITM
Mb2288|M.bovis_AF2122/97 LLLWLQRRVPRPESY--EDCPVVLGNPSAPRPWALPAQFWLYCGFTAITM
MAB_4615|M.abscessus_ATCC_1997 LLFWLRRRVPHPERY--EHDDYIRGAADRPHKLSLPLSFWLYSGFTAITM
Mvan_2778|M.vanbaalenii_PYR-1 LLAWLRVRVPEPARYEVEAAPSTKPVARVSFLRSLPRSFWTYAGFSAATM
MMAR_0136|M.marinum_M LITWVR----EPPRN----LAKAKPASILDGTRRLSRRYWAVVSFLVLFS
MUL_4961|M.ulcerans_Agy99 LIAWVR----EPPRN----LAKAKPASILDGTRRLPRRYWAVVSFLVLFS
Mflv_1475|M.gilvum_PYR-GCK VAVWAAVAVPRLAVLP-RTRQTLLDTVRRFSESSFVTPTLALAAATAALS
MAV_3974|M.avium_104 LFLGLRNSALAAPPP-----PTRSTVTMREALRVRAYQSALLSNFATGWS
MSMEG_6390|M.smegmatis_MC2_155 LLIRPHAPVITGNVS-----AKGHLGETLRYVSARPHIAAALVLMAVSGL
: .
Rv2265|M.tuberculosis_H37Rv LGFGTFGLLSFHMVSHGVLAAAMVPVVYAAAMAADALTALASGFSYDRYG
Mb2288|M.bovis_AF2122/97 LGFGTFGLLSFHMVSHGVLAAAMVPVVYAAAMAADALTALASGFSYDRYG
MAB_4615|M.abscessus_ATCC_1997 IGFATFGVLSFHMVQRGVLPVPAVPIVYAAAMAADAVAALLSGWAYDRVG
Mvan_2778|M.vanbaalenii_PYR-1 LGFTTFGVLSFHQVERGVVHVAVVPVIYAAAMVADALAALATGWVYDKVG
MMAR_0136|M.marinum_M IANFPDALLLLRLKQIG-FSVVGVIMAYVGYNAVYALASFPAGALADRLG
MUL_4961|M.ulcerans_Agy99 IANFPDALLLLRLKQIG-FSVVGVIMAYVGYNAVYALASFPVGALADRLG
Mflv_1475|M.gilvum_PYR-GCK AGVGFLPVLGTDFGLSPVVTGAVVSVLALTTAVVQPLAGRAADSGRISLT
MAV_3974|M.avium_104 AFGLRMALVPLFVSDVMGRGIGTIGVVLAAFAGGNALAVVPSGYLSDRMG
MSMEG_6390|M.smegmatis_MC2_155 LAFNWNVLLPTLARDTFGGDARVVGFAFTSMGVGAVFGGLALAGVLRGTS
:: : . .
Rv2265|M.tuberculosis_H37Rv AKTLAVLPILSILVVLFAF--TDNVTMVVIGTLVWGAAVGIQESTLRGVV
Mb2288|M.bovis_AF2122/97 AKTLAVLPILSILVVLFAF--TDNVTMVVIGTLVWGAAVGIQESTLRGVV
MAB_4615|M.abscessus_ATCC_1997 PKSLAALPIVGATVPMLAF--TDSLPGIVLGALLWGAAVGIQESTLRAVV
Mvan_2778|M.vanbaalenii_PYR-1 AVVLGALPVMAGLVPALAF--NDHLVPVVAGALVWGAAVGIQESTLRAVV
MMAR_0136|M.marinum_M RPVVYAFGLVFFAVGYLGLGITTDTATAWALIAAYGLFTACYDGVGKAWI
MUL_4961|M.ulcerans_Agy99 RPVVYAFGLVLFAVGYLGLGITTDTATAWALIAAYGLFTACYDGVGKAWI
Mflv_1475|M.gilvum_PYR-GCK SGLFTGVVVTAAGVAAAALP---GLVGLLGGAVVIGVGCGLITPLAFTML
MAV_3974|M.avium_104 RRTLLIVGLVTSGAATVWLGFVASLPVFLVAAGVVGVVTGIYMSPLQAAV
MSMEG_6390|M.smegmatis_MC2_155 KWLILNGCVLGAALALTGL--MPTVTIAYALLFVVGAASVTFRSTATTLL
. : : * :
Rv2265|M.tuberculosis_H37Rv ADLVA-SPRRASAYGVFAAGLGAATAGGGALIGWLYDIS---IGTLVVVV
Mb2288|M.bovis_AF2122/97 ADLVA-SPRRASAYGVFAAGLGAATAGGGALIGWLYDIS---IGTLVVVV
MAB_4615|M.abscessus_ATCC_1997 ADLVP-PPRRATAYGVYAAVLGTATAIGGALTGYLYGVS---IPMLIAVV
Mvan_2778|M.vanbaalenii_PYR-1 ADLVE-PARRATAYGIYAAVLGCAAAAGGALTGYLYGQS---VPLLVGVV
MMAR_0136|M.marinum_M SAIVS-AELQSSAQGVFQGLSGFAVLAAGLWAGFLWGVDGR-LPLLISGG
MUL_4961|M.ulcerans_Agy99 SAIVS-AELQSSAQGVFQGLSGFAVLAAGLWAGFLWGVDGR-LPLLISGG
Mflv_1475|M.gilvum_PYR-GCK ARSTP-EERLGQTMGAAEIGRECGDAAGPLVVAAIAAAS-T-VPFGFLGL
MAV_3974|M.avium_104 ADILGNEARAGLPVATVQMMSDLGAIVGSMAVGWAAEQIGYGWGFFISGV
MSMEG_6390|M.smegmatis_MC2_155 QLYSD-PGVRGRIISLLVLATNGTTPVGGPMIGWICTHANPRVACLVGGL
. . . . .
Rv2265|M.tuberculosis_H37Rv IALELMALVMMFAIRLPRVAPS-----------------
Mb2288|M.bovis_AF2122/97 IALELMALVMMFAIRLPRVAPS-----------------
MAB_4615|M.abscessus_ATCC_1997 GVIQLVALITAAPTLLRHAGQV-----------------
Mvan_2778|M.vanbaalenii_PYR-1 IGVQAIALAVLP--VVRRVAR------------------
MMAR_0136|M.marinum_M AGAVFALALLAAAAGTRRRAR------------------
MUL_4961|M.ulcerans_Agy99 AGAVFALALLAAAAGTRRRAR------------------
Mflv_1475|M.gilvum_PYR-GCK AAVVAASGVGVRRGRGRVGGVG-----------------
MAV_3974|M.avium_104 VLLIAAVGWVMAPETRTATELEADLMAASRTSSRCEQQL
MSMEG_6390|M.smegmatis_MC2_155 GTVAAALAHWAYLRKAGTRKDPIPL--------------