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TSGSAPQWLTRNLRVLSLVSLLQDAASELLYPLLPIYLATVLGAPPSVVGAVEGAAEGAASLTKIVSGPL GDRFARRPLIASGYGMAALGKLIVAAAGAWPGVLAGRVVDRLGKGLRGAPRDALLVDGVDPAQRGRAFGF HRTMDTLGAVIGPLLGLAGYELFDHQIGPVLYLAVIPAMLSVLLIAWVREPPRNLAKAKPASILDGTRRL PRRYWAVVSFLVLFSIANFPDALLLLRLKQIGFSVVGVIMAYVGYNAVYALASFPVGALADRLGRPVVYA FGLVLFAVGYLGLGITTDTATAWALIAAYGLFTACYDGVGKAWISAIVSAELQSSAQGVFQGLSGFAVLA AGLWAGFLWGVDGRLPLLISGGAGAVFALALLAAAAGTRRRAR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_4961 | - | - | 100% (394) | intergral membrane protein |
| M. ulcerans Agy99 | MUL_4170 | - | 4e-11 | 23.98% (392) | integral membrane transport protein |
| M. ulcerans Agy99 | MUL_0338 | - | 1e-08 | 25.46% (381) | integral membrane transport protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2288 | - | 7e-24 | 26.59% (361) | integral membrane protein |
| M. gilvum PYR-GCK | Mflv_1475 | - | 1e-08 | 25.76% (295) | major facilitator transporter |
| M. tuberculosis H37Rv | Rv2265 | - | 7e-24 | 26.59% (361) | integral membrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4615 | - | 4e-25 | 26.45% (397) | major facilitator transporter |
| M. marinum M | MMAR_0136 | - | 0.0 | 97.97% (394) | intergral membrane protein |
| M. avium 104 | MAV_1539 | - | 8e-13 | 27.02% (359) | major facilitator family protein transporter |
| M. smegmatis MC2 155 | MSMEG_2044 | - | 7e-07 | 26.16% (367) | integral membrane transport protein |
| M. thermoresistible (build 8) | TH_0476 | - | 1e-08 | 24.12% (340) | major facilitator superfamily protein MFS_1 |
| M. vanbaalenii PYR-1 | Mvan_2778 | - | 6e-32 | 30.03% (393) | major facilitator superfamily transporter |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_4961|M.ulcerans_Agy99 --------------MTSGSAPQWLTRNLRVLSLVSLLQDAASELLYPLLP
MMAR_0136|M.marinum_M --------------MTSGSAPQWLTRNLRVLSLVSLLQDAASELLYPLLP
Mb2288|M.bovis_AF2122/97 ---MGANGDVALSRIGATRPALSAWRFVTVFGVVGLLADVVYEGARSITG
Rv2265|M.tuberculosis_H37Rv ---MGANGDVALSRIGATRPALSAWRFVTVFGVVGLLADVVYEGARSITG
MAB_4615|M.abscessus_ATCC_1997 -----------------MPQRLSAWRFVTTFGVISMLADIVYEGARSITG
Mvan_2778|M.vanbaalenii_PYR-1 -------------MTGTPGVGLSAWRFVTTFGVVSLLADIVYEGARSITG
Mflv_1475|M.gilvum_PYR-GCK ------------------MAPLSPTAQRAPLLAAGFTTAFGAHAVAGTLG
MAV_1539|M.avium_104 --------MVMPNGPVAHQAGTRGYRRMTAALCGAGLASFAAMYCTQALL
TH_0476|M.thermoresistible__bu -----------------------VRRFAFPLLAYAFAAVMVGTTVPTPMY
MSMEG_2044|M.smegmatis_MC2_155 MTLADQRAASASKPSARTVALGSAVGTTIEWYDFYLYATAAALVFKPLFF
MUL_4961|M.ulcerans_Agy99 IYLATVLGAPPSVVGAVEGAAEGAASLTKIVSGPLGDRFAR-RPLIASGY
MMAR_0136|M.marinum_M IYLTTVLGAPPSVVGAVEGAAEGAASLTKVVSGPLGDRFAR-RPLIASGY
Mb2288|M.bovis_AF2122/97 PLLAS-LGATGLVVGVVTGVGEAAALGLRLVSGPLADRSRRFWAWTIAGY
Rv2265|M.tuberculosis_H37Rv PLLAS-LGATGLVVGVVTGVGEAAALGLRLVSGPLADRSRRFWAWTIAGY
MAB_4615|M.abscessus_ATCC_1997 PLLAS-LGASALVVGVVTGIGEAAALALRLVSGPLTDRTRKFWAWTISGY
Mvan_2778|M.vanbaalenii_PYR-1 PLLAS-LGATAVVVGVVTGVGEAAALILRMVSGPLADRTGRFWTWTIGGY
Mflv_1475|M.gilvum_PYR-GCK TTTTG-TAASLLTLGAMLAIYDGAEVILKPLFGTLADRIGA-RTVLIAGL
MAV_1539|M.avium_104 PALSAHHRIGPATAALTVSLTTGALALSIIPASVLSERYGRTRVMLISGV
TH_0476|M.thermoresistible__bu AVYAERLGFGVLTTTVVFAGYTAGVLFALVVFGRWSDALGR-RPMLLAGV
MSMEG_2044|M.smegmatis_MC2_155 PNVSS--TAGTLAAFATYAAGFGARPLGALISGHYGDRVGR-KTVLVAAL
: . . .. . : ..
MUL_4961|M.ulcerans_Agy99 GMAALGKLIVAAAG--------AWPGVLAGRVVDRLGKGLRGAPRDALLV
MMAR_0136|M.marinum_M GMAALGKLIVAAAG--------AWPGVLAGRVVDRLGKGLRGAPRDALLV
Mb2288|M.bovis_AF2122/97 TLTVVTVPLLGIAG--------ALWVACALVIAERVGKAVRGPAKDTLLS
Rv2265|M.tuberculosis_H37Rv TLTVVTVPLLGIAG--------ALWVACALVIAERVGKAVRGPAKDTLLS
MAB_4615|M.abscessus_ATCC_1997 ALTVVTVPFLGVSS--------VLWIAATLVIAERVGKAVRSPAKDTLLS
Mvan_2778|M.vanbaalenii_PYR-1 FLTVVTVPFLGAVG--------VLWAAAALIIAERVGKAVRSPAKDTLLS
Mflv_1475|M.gilvum_PYR-GCK AVFAVASLSFAVAD--------ETAWLWAARLGQGIGAAAFSPAASALVA
MAV_1539|M.avium_104 ASSVIG-LLLPFSP--------SLGVLVFGRAVQGVALAGIPAVAMALLA
TH_0476|M.thermoresistible__bu GCAIVSALVFLIAG--------SVPQLIAARFVSGMSAGIFTGTATAAVI
MSMEG_2044|M.smegmatis_MC2_155 LGMGISTFLIGLLPTYAQVGLLAPALLVTLRLLQGLAVGAEWGGAALLSV
: . . :. .
MUL_4961|M.ulcerans_Agy99 DGVDPAQRGRAFGFHRTMDTLGAVIGP--------LLGLAGYELFDHQIG
MMAR_0136|M.marinum_M DGVEPAQRGRAFGFHRTMDTLGAVIGP--------LLGLAGYELFDHQIG
Mb2288|M.bovis_AF2122/97 HAASVTGRGRGFAVHEALDQVGAMIGP--------LTVAGMLAITGNAYA
Rv2265|M.tuberculosis_H37Rv HAASVTGRGRGFAVHEALDQVGAMIGP--------LTVAGMLAITGNAYA
MAB_4615|M.abscessus_ATCC_1997 HATAVTGRGKGFAVHEAMDQIGAITGP--------LLVAGMLALTHVNYL
Mvan_2778|M.vanbaalenii_PYR-1 HATAVTGRGRGFAVHEAMDQIGAVAGP--------LAVAAMLVVFGGDYA
Mflv_1475|M.gilvum_PYR-GCK RLAPASGQGRAFGTYGSYKSVGYTLGP--------LIGGAIVTFGG----
MAV_1539|M.avium_104 EEVDASSLGSAMGRYIAGTTIGGLAGR--------IVPSVVVQVGTWRVA
TH_0476|M.thermoresistible__bu EAAPERRRSRAAAVATVANIGGLGAGP--------LLAGILVQYAPWPLH
MSMEG_2044|M.smegmatis_MC2_155 EHAPPGRRGLFGSFTQLGSPAGMLLSTGVFSVTRAVCGPEAFLAYGWRIP
. . . * . :
MUL_4961|M.ulcerans_Agy99 PVLYLAVIPAMLSVLLIAWVR----EPPRN----LAKAKPASILDGTRRL
MMAR_0136|M.marinum_M PVLYLAVIPAVLSVLLITWVR----EPPRN----LAKAKPASILDGTRRL
Mb2288|M.bovis_AF2122/97 PALGVLTLPGGAALALLLWLQRRVPRPESY--EDCPVVLGNPSAPRPWAL
Rv2265|M.tuberculosis_H37Rv PALGVLTLPGGAALALLLWLQRRVPRPESY--EDCPVVLGNPSAPRPWAL
MAB_4615|M.abscessus_ATCC_1997 PTFAILALPGGATLLLLFWLRRRVPHPERY--EHDDYIRGAADRPHKLSL
Mvan_2778|M.vanbaalenii_PYR-1 PTLALLAVPGVGVLALLAWLRVRVPEPARYEVEAAPSTKPVARVSFLRSL
Mflv_1475|M.gilvum_PYR-GCK -LQALFAVMAALAAAVAVWAAVAVPRLAVLP-RTRQTLLDTVRRFSESSF
MAV_1539|M.avium_104 LLACSLITLAGTAVFAVLVPRSRFFTPKPAS---VRAALRNLAGHLRNPV
TH_0476|M.thermoresistible__bu LTFWVHIVLMVLAAAAIAVAPETSPRTGRLG-------VQRLSLPPQVRK
MSMEG_2044|M.smegmatis_MC2_155 FLLSAVLVVIGLVIRLRLTDADVFLRVKEAGEVARMPVLEVLRTQPRGVV
MUL_4961|M.ulcerans_Agy99 PRRYWAVVSFLVLFSIANFPDALLLLRLKQIG-FSVVGVIMAYVGYNAVY
MMAR_0136|M.marinum_M SRRYWAVVSFLVLFSIANFPDALLLLRLKQIG-FSVVGVIMAYVGYNAVY
Mb2288|M.bovis_AF2122/97 PAQFWLYCGFTAITMLGFGTFGLLSFHMVSHGVLAAAMVPVVYAAAMAAD
Rv2265|M.tuberculosis_H37Rv PAQFWLYCGFTAITMLGFGTFGLLSFHMVSHGVLAAAMVPVVYAAAMAAD
MAB_4615|M.abscessus_ATCC_1997 PLSFWLYSGFTAITMIGFATFGVLSFHMVQRGVLPVPAVPIVYAAAMAAD
Mvan_2778|M.vanbaalenii_PYR-1 PRSFWTYAGFSAATMLGFTTFGVLSFHQVERGVVHVAVVPVIYAAAMVAD
Mflv_1475|M.gilvum_PYR-GCK VTPTLALAAATAALSAGVGFLPVLGTDFGLSPVVTGAVVSVLALTTAVVQ
MAV_1539|M.avium_104 LAKLFAVG--FVLMGGFVTVYNYLGYRLAARPFGLAPSVVGLLFLLYLVG
TH_0476|M.thermoresistible__bu VFAIASLAAFAGFAVTGLFTAVAPSFLAEVIGVRNHAVAGAVAASIFAAS
MSMEG_2044|M.smegmatis_MC2_155 ITTGLRISQIALFVLLTTYSLTYLQDQTSAGGGVGLTAVLIASAIGLITT
. .
MUL_4961|M.ulcerans_Agy99 ALASFPVGALADRLGRPVVYAFGLVLFAVGYLGLGITTDTATAWALIAAY
MMAR_0136|M.marinum_M ALASFPAGALADRLGRPVVYAFGLVFFAVGYLGLGITTDTATAWALIAAY
Mb2288|M.bovis_AF2122/97 ALTALASGFSYDRYGAKTLAVLPILSILVVLFAF--TDNVTMVVIGTLVW
Rv2265|M.tuberculosis_H37Rv ALTALASGFSYDRYGAKTLAVLPILSILVVLFAF--TDNVTMVVIGTLVW
MAB_4615|M.abscessus_ATCC_1997 AVAALLSGWAYDRVGPKSLAALPIVGATVPMLAF--TDSLPGIVLGALLW
Mvan_2778|M.vanbaalenii_PYR-1 ALAALATGWVYDKVGAVVLGALPVMAGLVPALAF--NDHLVPVVAGALVW
Mflv_1475|M.gilvum_PYR-GCK PLAGRAADSGRISLTSGLFTGVVVTAAGVAAAALP---GLVGLLGGAVVI
MAV_1539|M.avium_104 TGTSVVAGRLADRRGRPLVLGAALP-IAVAGLLLTVPPSLAAIVAGVGVF
TH_0476|M.thermoresistible__bu AVTQVLGASVSPRRAVAVGCALLIVGMVFLAAALV-WSSLPALIATAVVA
MSMEG_2044|M.smegmatis_MC2_155 PLWGIVSDRIGRRPPYLFGAIAGVVALVLFFLAADSGSSVLIILAIVFGV
. : .
MUL_4961|M.ulcerans_Agy99 GLFTACYDGVGKAWISAIVS-AELQSSAQGVFQGLSGFAVLAAGLWAGFL
MMAR_0136|M.marinum_M GLFTACYDGVGKAWISAIVS-AELQSSAQGVFQGLSGFAVLAAGLWAGFL
Mb2288|M.bovis_AF2122/97 GAAVGIQESTLRGVVADLVA-SPRRASAYGVFAAGLGAATAGGGALIGWL
Rv2265|M.tuberculosis_H37Rv GAAVGIQESTLRGVVADLVA-SPRRASAYGVFAAGLGAATAGGGALIGWL
MAB_4615|M.abscessus_ATCC_1997 GAAVGIQESTLRAVVADLVP-PPRRATAYGVYAAVLGTATAIGGALTGYL
Mvan_2778|M.vanbaalenii_PYR-1 GAAVGIQESTLRAVVADLVE-PARRATAYGIYAAVLGCAAAAGGALTGYL
Mflv_1475|M.gilvum_PYR-GCK GVGCGLITPLAFTMLARSTP-EERLGQTMGAAEIGRECGDAAGPLVVAAI
MAV_1539|M.avium_104 TGGFFAAHTVASGWVGAVAQ-RDR-AEASALYLFSYYLGGSVAGAFGGVL
TH_0476|M.thermoresistible__bu GAGQGLSFSRGLAAVSARTP-SDQRGEVSSTYFVVAYVALLVPVIGEGWA
MSMEG_2044|M.smegmatis_MC2_155 NIAHDAMYGPQAAWFGELFDTRVRYSGASLGYSIGAVLSGGFAPLIAASL
.. . . . .
MUL_4961|M.ulcerans_Agy99 WGVDGR---LPLLISGGAGAVFALALLAAAAGTRRRAR---------
MMAR_0136|M.marinum_M WGVDGR---LPLLISGGAGAVFALALLAAAAGTRRRAR---------
Mb2288|M.bovis_AF2122/97 YDIS-----IGTLVVVVIALELMALVMMFAIRLPRVAPS--------
Rv2265|M.tuberculosis_H37Rv YDIS-----IGTLVVVVIALELMALVMMFAIRLPRVAPS--------
MAB_4615|M.abscessus_ATCC_1997 YGVS-----IPMLIAVVGVIQLVALITAAPTLLRHAGQV--------
Mvan_2778|M.vanbaalenii_PYR-1 YGQS-----VPLLVGVVIGVQAIALAVLPVVR--RVAR---------
Mflv_1475|M.gilvum_PYR-GCK AAAS-T---VPFGFLGLAAVVAASGVGVRRGRGRVGGVG--------
MAV_1539|M.avium_104 YGVGGWSATVCFVVVLLMAGAALVALLVRDNGFRIGRRVVAGVASVK
TH_0476|M.thermoresistible__bu AHHWGLR-TAGISFAVGVAVLAIGCLIAILIQESRDPQAI-------
MSMEG_2044|M.smegmatis_MC2_155 LAAGDG---SPWLIVGYFVVLTVITVAAAYFARETHKDEIGDE----
.