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M. marinum M MMAR_2471 (pks7)

annotation: polyketide synthase Pks7
coordinates: 2993342 - 2999704
length: 2120

MDSTPDELITALRKTLKENERLKRENRDHLAQATEPVAVVGMGCRYPGGIETPEGLWEMVAAGRDVVSDF
PTDRGWDGASLFDPDPDAVGKSYTRSGGFLTDVAGFDAEFFGIAPSEVMAMDPQQRLLLEVSWEALERTG
IDPTTLRGSATGVFVGVFHGSYGGQGRVPGDLERYGLRGSTLSVASGRVAYVLGLEGPAVSVDTACSSSL
VALHLAVQSLRSRECDLALVGGVTVMATPAMFIEFSRQRALSADGRCKAYAGAADGTAFSEGAGALVLER
LTDAQRLGHPVLAVVRGSAVNQDGASNGLATPNGPSQQRVIRAALASARLGVADVDVVEGHGTGTTLGDP
IEAQAILATYGQDRTGPGKEPLWLGSIKSNMGHTSAAAGVAGVIKMTLAMQHGVLPQTLHVDVPTPHVDW
SAGSVSLLTEARPWPETGRARRAGISSFGISGTNAHVILEQAPAAEEVAAQHRTDLTPWILAARSAPALV
NQARRLAQWVSDRPDLDVADVGWSLATTRSVFEHRAVVVGADRTQLIQGLAGFVDGEPRAGVVVGRARPV
GKTVFVFPGQGSQWVGMGVDLLDTSTVFADQMHRCEKALAEYVSWSLLDVVRAVPGAPGLNRVDVVQPVL
WAIMVSLAELWRSAGVLPDAVIGHSQGEIAAAYVAGALSLEDAARVVARRSQLLVQLSGAGGMVSLACGL
ERARQLVASWSDRLSIAAVNGVSAIVVSGEVDALDALIGRCEADDIRARRIDVDYASHSAQVEAIRAELA
EALDGIAPQSTSTAFISTVTGEFTDTAGLDADYWHRSIRQTVQFERAIRTAFNSGCQVFIESSPHPVLMA
GIEETLAGQQDSGEAIVIPSLGRDDGGLQRFWLSVAQAHVAGVRVDWASIIGAGRRVALPTYGFQHRRFW
LGQLDAGRTDVGGLGQAGAAHGLLGAVVERPDSGGVVLTGQLSVALQPWLAGHAVAGTVLFPGAGFVELA
IRAGDEVGCAAVEELTLSAPLVLPTVGGVQLQVVVGPADQSDHRTVEVYSRGDQSLSEWSLHAEGVLAPA
AVASVGQLTAWPPEGATALDLGGVYDRLAARGYEYGPAFRGLQAVWESGDEIFAEVALPEDAGAQIGGFG
IHPALLDAALHALVLTAEQNQTVLPFAWQGVSLHAAGASRCRVRIAQSRSGSVAMELADSAGLPVLTVRD
LAFRPVSDQTSSAGTAGGGGLLEVVWSPLARPGDDTADIPVTLWDLASQVELSAGAVESTYVATHGALGA
LQSWLASDQPGVLAVVTHGAVGLADEDVTDLAGSAVWGLVRSAQAEHPGRVVLVDTDGSVELGAVLNSGE
PQLVVRAGVAYQARLKPAESLLRLPPPGENWRLVTGGGGTLDDVKVGGCAPSGLMTGQLRVAVAAVGVNF
RDVLVALGMYPGGGELGVEGAGIVTEVGPGVSGVAVGDAVMGLLGVVGPEAVVDHRLVTAVPPGWSLQTA
ASVPVVFLTAFYGLRVLAEVRSGQKLLVHAATGGVGMAAVQLARLWGLEVFATASPGKWDTLRAMGFDDD
HIANSRTLEFEEKFRAGTGGVGVDAVLNSLAGEFVDASLRLLVPGGRFIEMGKTDLRDPQTMAEQHRGVG
YRAFDLIEAGPDLIARMLAELSRLLCAETLTPLPIKTFDVRLARQAYRFVSQARHIGKVVLTLPDETGAV
PAGALAGGTVIITGGTGMAGTALARHVVSRHRVANVILVSRSGAQAEGTSELLGQLQDAGAEAAVVACDV
SDRDAVAELLAQVPARYPLRGVIHAAGVLDDGLIASLTPQRVDTVLRAKIDGAWNLHELTRGLNLSAFVL
FSSMAGIIGTAGQGNYAAANSFLDGLAVHRRALGLPGVSVAWGLWEQASAMTRHLGERDKARMSRVGLAT
LSTEHALELFDAAVVADRAVVVATRLDANALKSNSAALPPLLGELAARPKRRVISDADAGDNIAAATGLV
ARLHGLSAEQRQRELVDVVCSNAATVLGRSSTADINAHRAFQELGFDSLTAVELRNRLKTATGLTLSPTL
IFDYPSPAALAEHLGIRLATATAQPDLMRRFDDLARELDKLINRPDWTHEDKGKLSGRLHDILADLSADD
DITTASESQLFAILDEELGS
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_2471pks7-100% (2120)polyketide synthase Pks7
M. marinum MMMAR_2472pks80.062.34% (2135) polyketide synthase, Pks8
M. marinum MMMAR_0102-0.061.06% (2098) polyketide synthase PKS

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1689pks70.070.49% (2138) polyketide synthase pks7
M. gilvum PYR-GCKMflv_0405-0.036.55% (2137) beta-ketoacyl synthase
M. tuberculosis H37RvRv1661pks70.070.49% (2138) polyketide synthase pks7
M. leprae Br4923MLBr_00135-0.055.70% (2088) putative polyketide synthase
M. abscessus ATCC 19977MAB_0939-0.036.16% (2146) polyketide synthase
M. avium 104MAV_3109-0.070.80% (2137) RifB protein
M. smegmatis MC2 155MSMEG_0408-0.036.81% (2135) type I modular polyketide synthase
M. thermoresistible (build 8)TH_4621-0.034.86% (1859) PUTATIVE mycocerosic acid synthase
M. ulcerans Agy99MUL_2266pks120.059.83% (2066) polyketide synthase, Pks12
M. vanbaalenii PYR-1Mvan_0269-0.036.59% (2121) beta-ketoacyl synthase

CLUSTAL 2.0.9 multiple sequence alignment


MAB_0939|M.abscessus_ATCC_1997      ------------------------------MDSAENPIESTPRFAIIGYA
Mvan_0269|M.vanbaalenii_PYR-1       ------------------------------MGSAEHPNGPAPRFAIVGYA
Mflv_0405|M.gilvum_PYR-GCK          ------------------------------MGSAAHQGESAHRFAIVGYA
MSMEG_0408|M.smegmatis_MC2_155      ------------------------------MVSAEHPIEPTPSFAIIGYA
Mb1689|M.bovis_AF2122/97            -------MNSTPEDLVKALRRSLKQNERLKRENRDLLARTTEPVAVVGMG
Rv1661|M.tuberculosis_H37Rv         -------MNSTPEDLVKALRRSLKQNERLKRENRDLLARTTEPVAVVGMG
MMAR_2471|M.marinum_M               -------MDSTPDELITALRKTLKENERLKRENRDHLAQATEPVAVVGMG
MAV_3109|M.avium_104                -------MSGDTEELVRALRQSLKENERLKRENRRYLVAATEPVAVVGMG
MUL_2266|M.ulcerans_Agy99           -------MVDQLQHATEALRKALVQVERLKRTKRALLERSSEPIAIVGMS
MLBr_00135|M.leprae_Br4923          MTASVEGADQKSEKLISYLKKVVVELDETRARLREYEQRATEPVAVVGIG
TH_4621|M.thermoresistible__bu      --------------------------------VNIVGDTPVNAVAVIGMA
                                                                           .   .*::* .

MAB_0939|M.abscessus_ATCC_1997      ARFPG-AADAEEFWDVLREGRDAISEVPADR-WDAEEFFDPEPGAPGKVV
Mvan_0269|M.vanbaalenii_PYR-1       ARFPG-APDADAFWDVLREGRDAISDVPRDR-WDAEEFFDPEPGAPGKVV
Mflv_0405|M.gilvum_PYR-GCK          GRFPG-ARDAESFWELLADGRDAISEVPEDR-WDVEAFFDPDPSTPGKVV
MSMEG_0408|M.smegmatis_MC2_155      ARFPG-AASAEEYWALLRDGREAISDVPKDR-WDIEEFFDPDPSTPGKVV
Mb1689|M.bovis_AF2122/97            CRYPGGVDSPETLWELVAHGRDAVSEFPADRGWDVAGLFDPDPDAVGKSY
Rv1661|M.tuberculosis_H37Rv         CRYPGGVDSPETLWELVAHGRDAVSEFPADRGWDVAGLFDPDPDAVGKSY
MMAR_2471|M.marinum_M               CRYPGGIETPEGLWEMVAAGRDVVSDFPTDRGWDGASLFDPDPDAVGKSY
MAV_3109|M.avium_104                CRYPGGVDSPEALWEMVVEGRDVVSEFPADRGWDLAGLFDADPDAVGKSY
MUL_2266|M.ulcerans_Agy99           CRFPGGVDSPEGLWQMVAEGRDVMSDFPTDRGWDLADLFDPDPDTPHKSY
MLBr_00135|M.leprae_Br4923          CRFPGGVDSPDRLWDVVSECRDVVSEFPTDRGWDVDGLFDPDPDAEGKTY
TH_4621|M.thermoresistible__bu      CRLPGGIDSPQRLWEALLRGDDMVTEIPVDR-WDADDYFDPEPGVPGRTV
                                     * **    .:  *  :    : :::.* ** **    **.:*..  :  

MAB_0939|M.abscessus_ATCC_1997      TRRAGFVEDVTGFDAPFFGMSTREVRLMDPQHRLLLETAWRAVEHSGIAP
Mvan_0269|M.vanbaalenii_PYR-1       TRRAGFVDDVTGFDAPFFGMSTREVRMMDPQHRLLLETAWRAVEHSGTAP
Mflv_0405|M.gilvum_PYR-GCK          TRRAGFVDDVSGFDAPFFGMSTREVRLMDPQHRLLLETAWRAIEHSGTAP
MSMEG_0408|M.smegmatis_MC2_155      TRRAGFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAP
Mb1689|M.bovis_AF2122/97            TRCGGFLTDVAGFDAEFFGIAPSEALAMDPQQRLLLEVSWEALERAGIDP
Rv1661|M.tuberculosis_H37Rv         TRCGGFLTDVAGFDAEFFGIAPSEALAMDPQQRLLLEVSWEALERAGIDP
MMAR_2471|M.marinum_M               TRSGGFLTDVAGFDAEFFGIAPSEVMAMDPQQRLLLEVSWEALERTGIDP
MAV_3109|M.avium_104                CRCGGFLTGVGDFDAAFFGIAPSEALAMDPQQRLLLEVSWEALERAGIDP
MUL_2266|M.ulcerans_Agy99           ASTGGFVDGVADFDPGFFGIAPSEALAMDPQHRMLLELSWEALERSGIDP
MLBr_00135|M.leprae_Br4923          TRWGAFLDDAAGFDAGFFGIAPSEVLAMDPQQRLMLEVSWEALEYAGIDP
TH_4621|M.thermoresistible__bu      SRWGAFLDDVAGFDPEFFGISEREAISIDPQQRLLLETSWEAMEHAGLTP
                                       ..*: .. .**. ***::  *.  :***:*:::* :*.*:* :*  *

MAB_0939|M.abscessus_ATCC_1997      TDLAETNSGVFVGLATHDYLGMASDELTFPEIEAYMAIGTSNAAAAGRIS
Mvan_0269|M.vanbaalenii_PYR-1       TALAGSNTGVFVGLATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRIS
Mflv_0405|M.gilvum_PYR-GCK          SELANTNTGVFVGLATHDYLGMASDELSYPEIEAYMAIGTSNAAAAGRIS
MSMEG_0408|M.smegmatis_MC2_155      TSLANSNTGVFVGLATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRIS
Mb1689|M.bovis_AF2122/97            ITLRGSQTGVFAGVFHGSYGGQG---RVPGDLERYGLRGSTLSVASGRVA
Rv1661|M.tuberculosis_H37Rv         ITLRGSQTGVFAGVFHGSYGGQG---RVPGDLERYGLRGSTLSVASGRVA
MMAR_2471|M.marinum_M               TTLRGSATGVFVGVFHGSYGGQG---RVPGDLERYGLRGSTLSVASGRVA
MAV_3109|M.avium_104                ATLRGSATGVFAGIFHGSYGGQG---RVPGNLERYGLRGSTLSVASGRVA
MUL_2266|M.ulcerans_Agy99           TGLRGSATGVFAGLIVQGYG------MFAEEIEGYRLTGMTSSVASGRVA
MLBr_00135|M.leprae_Br4923          LSLRGSATGVFTGIFAPSYGS-----RDTGGLQGYGLTGTAVSVASGRVS
TH_4621|M.thermoresistible__bu      ADVEGSSTGVFVGLSHDDYALLTS--DAGALEEAYGFTGSAFSMASGRIA
                                      :  : :***.*:   .*             : *   * : : *:**::

MAB_0939|M.abscessus_ATCC_1997      YRLGLQGPSVAVDTACSSSLVAIHQACQALQLGECDLALAGGANVLLTPA
Mvan_0269|M.vanbaalenii_PYR-1       YRLGLQGPAVAVDTACSSSLVAIHQACQALRLGECDLALAGGANVLLTPA
Mflv_0405|M.gilvum_PYR-GCK          YRLGLQGPAVAVDTACSSSLVAIHQACQALRLGECDLALAGGANVILTPA
MSMEG_0408|M.smegmatis_MC2_155      YRLGLQGPAVAVDTACSSSLVAIHQACQALRLNECDLALAGGANVLLTPA
Mb1689|M.bovis_AF2122/97            YVLGLQGPAVSVDTACSSSLVALHLAVQSLRLGECDLALVGGVTVMATPA
Rv1661|M.tuberculosis_H37Rv         YVLGLQGPAVSVDTACSSSLVALHLAVQSLRLGECDLALVGGVTVMATPA
MMAR_2471|M.marinum_M               YVLGLEGPAVSVDTACSSSLVALHLAVQSLRSRECDLALVGGVTVMATPA
MAV_3109|M.avium_104                YALGLEGPAVSVDTACSSSLVALHLAAQSLRSGECDLALAGGVTVMATPA
MUL_2266|M.ulcerans_Agy99           YVLGLEGPAVSVDTACSSSLVALHMAVQSLRSGECDLALAGGATVNATPT
MLBr_00135|M.leprae_Br4923          YVLGLEGPAVSVDTACSSSLVAIHWAMSSLRSGECDLALAGGVTVMGLPS
TH_4621|M.thermoresistible__bu      YRLGVHGPAVTVDTACSSSLLAVHMACRSLQVGESDLALAGGAMVMLEPR
                                    * **:.**:*:*********:*:* *  :*:  *.****.**. *   * 

MAB_0939|M.abscessus_ATCC_1997      TMITFSHAHMLAPDGKCKTFDAAADGYVRGEGSGVIVIKRLEDAIRDGDR
Mvan_0269|M.vanbaalenii_PYR-1       TMITFSNAHMLAPDGRCKTFDAAADGYVRGEGCGVIVIKRLEDAVRDGDR
Mflv_0405|M.gilvum_PYR-GCK          TMITFSNAHMLAPDGRCKTFDAAADGYVRGEGCGVIVIKRLEDAVRDGDR
MSMEG_0408|M.smegmatis_MC2_155      TMITFSNAHMLAPDGRCKTFDAAADGYVRGEGCGVVVVKRLEDAVRDGDR
Mb1689|M.bovis_AF2122/97            MFIEFSRQRALSADGRCKAYAGAADGTAFAEGAGVLVLARLADARRLGHP
Rv1661|M.tuberculosis_H37Rv         MFIEFSRQRALSADGRCKAYAGAADGTAFAEGAGVLVLARLADARRLGHP
MMAR_2471|M.marinum_M               MFIEFSRQRALSADGRCKAYAGAADGTAFSEGAGALVLERLTDAQRLGHP
MAV_3109|M.avium_104                MFIEFSRQRALAADGRCKAYAGAADGTGFSEGVGVLVLERLSDARRLGHS
MUL_2266|M.ulcerans_Agy99           VFVEFSRHRGLAPDGRSKAYAGAADGVGWSEGGAMLVVERLSDAQRLGHP
MLBr_00135|M.leprae_Br4923          IFVGFSRQRGLAADGRCKAFARAADGTGWGEGAGVVVLERLSDAQRLGHT
TH_4621|M.thermoresistible__bu      KYTSASGLGMLSPTGRCHAFDVAADGFVRSEGSVMLLLKRLPDALRDNDR
                                         *    *:. *:.:::  ****   .**   ::: ** ** * .. 

MAB_0939|M.abscessus_ATCC_1997      IRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKRAGVAPSEVGYLEA
Mvan_0269|M.vanbaalenii_PYR-1       IRAVIRGSSINQDGASGGLTVPNGVAQQRVIADALKRSDLEPKDVGYLEA
Mflv_0405|M.gilvum_PYR-GCK          IRAVIRGSAINQDGASGGLTVPNGVAQQRVIGDALSRAGLAPGDVDYLEA
MSMEG_0408|M.smegmatis_MC2_155      IRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKRAGLRPADVGYLEA
Mb1689|M.bovis_AF2122/97            VLALVRGSAVNQDGASNGLATPNGPAQQRVITAALASARLGVADVDVVEG
Rv1661|M.tuberculosis_H37Rv         VLALVRGSAVNQDGASNGLATPNGPAQQRVITAALASARLGVADVDVVEG
MMAR_2471|M.marinum_M               VLAVVRGSAVNQDGASNGLATPNGPSQQRVIRAALASARLGVADVDVVEG
MAV_3109|M.avium_104                VLAVLRGSAVNQDGASNGLATPNGPSQQRVIRAALANARLGAADVDLVEG
MUL_2266|M.ulcerans_Agy99           VLALVRGSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEG
MLBr_00135|M.leprae_Br4923          VLAVVRGSAVNQDGASNGLTAPNGLAQQRVIQAALTNAGLSSADVDVVEA
TH_4621|M.thermoresistible__bu      ILAVVRGTAANQDGRTENISTPSIQAQADVYRSALAVAGVDPATVGMVEA
                                    : *::**:: **** : .::.*.  :*  *   **  : :    *. :*.

MAB_0939|M.abscessus_ATCC_1997      HGTGTSLGDPIEAQAAGAAYGIG----RETNDPLLIGSAKTNIGHLEAAA
Mvan_0269|M.vanbaalenii_PYR-1       HGTGTSLGDPIEAQAAGAVLGAG----REPSRPLLIGSAKTNIGHLEAAA
Mflv_0405|M.gilvum_PYR-GCK          HGTGTSLGDPIEAQAAGAALGPG----REPQRPLLIGSAKTNIGHLEAAA
MSMEG_0408|M.smegmatis_MC2_155      HGTGTSLGDPIEAQAAGEVLGAG----RAPEEPLLIGSAKTNIGHLEAAA
Mb1689|M.bovis_AF2122/97            HGTGTTLGDPIEAQAILATYGQ-----RPADRPLWLGSIKSNIGHTSAAA
Rv1661|M.tuberculosis_H37Rv         HGTGTTLGDPIEAQAILATYGQ-----RPADRPLWLGSIKSNIGHTSAAA
MMAR_2471|M.marinum_M               HGTGTTLGDPIEAQAILATYGQDR--TGPGKEPLWLGSIKSNMGHTSAAA
MAV_3109|M.avium_104                HGTGTMLGDPIEAQALLATYGQD----RPVDEPLWLGSIKSNMGHTSAAA
MUL_2266|M.ulcerans_Agy99           HGTGTTLGDPIEAQALLATYGQDRGSAGAAGKALWLGSIKSNMGHTQAAA
MLBr_00135|M.leprae_Br4923          HGTATTLGDPIEAQALLATYGQG----RPADQPLWVGSIKSNMGHTQAAA
TH_4621|M.thermoresistible__bu      HGTGTPVGDPIEYNSLTQVYGKTG--------PCALTSVKTNFGHAESAA
                                    ***.* :***** ::   . *           .  : * *:*:** .:**

MAB_0939|M.abscessus_ATCC_1997      GIAGVIKVILSLENELLPQHRNFQNPSPHIPWDRLPVEVVREARPWGRN-
Mvan_0269|M.vanbaalenii_PYR-1       GIAGVIKVILSLEHRTLPKHLNFENPSPHIPWDRLAVEVVKETIPWERD-
Mflv_0405|M.gilvum_PYR-GCK          GIAGVIKVVLSLEHETLPKHLNFENPSPHIPWDRLPVEVVKESIPWRRGQ
MSMEG_0408|M.smegmatis_MC2_155      GIAGVIKVVMALENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRN-
Mb1689|M.bovis_AF2122/97            GVAGVIKMVQAMRHGVLPKTLHVDVPTPHVDWSAGAVSLLTEPRPWHVP-
Rv1661|M.tuberculosis_H37Rv         GVAGVIKMVQAMRHGVLPKTLHVDVPTPHVDWSAGAVSLLTEPRPWHVP-
MMAR_2471|M.marinum_M               GVAGVIKMTLAMQHGVLPQTLHVDVPTPHVDWSAGSVSLLTEARPWPET-
MAV_3109|M.avium_104                GAGGVIKMVQAIRHGVMPKTLHVDEPTPQVDWSAGAVSLLTEARPWPAR-
MUL_2266|M.ulcerans_Agy99           GVAGVIKMVQAMRHEVLPATLHVDVPSPHVDWSAGAVELLTEAQPWPAES
MLBr_00135|M.leprae_Br4923          GVAGVIKMVQAMRHHVMPATLHVDEPSPRVDWTTGAVSVLTEARDWSVE-
TH_4621|M.thermoresistible__bu      GALGMMKAILALQHGVVPQNLHFTRLPDEMAAIETNLFVPQATTLWPVR-
                                    *  *::*   ::.:  :*   :.   . .:      : :   .  *    

MAB_0939|M.abscessus_ATCC_1997      --GRPRIAGVSSFGFAGTNAHVILEEAPVVSRDAVEPPAPAGGRKFSILP
Mvan_0269|M.vanbaalenii_PYR-1       --GGPRIAGVSSFGFAGTNAHVILEEAP--EQAAAPGPVQQPDRRFSLLP
Mflv_0405|M.gilvum_PYR-GCK          RGGRPRIAGVSSFGFAGTNAHVILEEAP---LAAEPAQESVDDGRFTLLP
MSMEG_0408|M.smegmatis_MC2_155      --GKPRIAGVSSFGFAGTNAHVILEEAPAVGTPATTEPVE-DPRRYSVLP
Mb1689|M.bovis_AF2122/97            --GRPRRAGVSSFGISGTNAHVILEEAP-AVEPVGAAHGNDP--VAVPWV
Rv1661|M.tuberculosis_H37Rv         --GRPRRAGVSSFGISGTNAHVILEEAP-AVEPVGAAHGNDP--VAVPWV
MMAR_2471|M.marinum_M               --GRARRAGISSFGISGTNAHVILEQAP-AAEEVAAQHRTD----LTPWI
MAV_3109|M.avium_104                --DRPRRAGVSSFGISGTNAHVIVEQY----EPETVAPQGGD--VVVPWV
MUL_2266|M.ulcerans_Agy99           AGDRVRRAGVSSFGISGTNAHVIVEAAP-RVEVGGSS-GGAV--PVVPWV
MLBr_00135|M.leprae_Br4923          --GRPRRAGVSSFGISGTNAHVILEEAP-TPVEASYSTADQQRLSVVPWV
TH_4621|M.thermoresistible__bu      -EGCPRRAAVSSYGMSGTNVHAVLEQAP-EPVQRPEESADTDAAGPLVFA
                                      .  * *.:**:*::***.*.::*                         

MAB_0939|M.abscessus_ATCC_1997      LSARTPAALAQLADKYRAWLNAH-PEAALADLCFTAGVGRAHLEHRAALV
Mvan_0269|M.vanbaalenii_PYR-1       LSARTPAALTQLAGQYRDWWTAH-PEATLADVCFTAGAGRAHLEHRAALV
Mflv_0405|M.gilvum_PYR-GCK          LSARTPAALMAVADRYRDWLVAN-PDATLADLCFTAGTARSHLEHRAALV
MSMEG_0408|M.smegmatis_MC2_155      LSARTPEALVRLAGEYRDWLRAH-PQARLADVSHTAGTARAHLEQRAALV
Mb1689|M.bovis_AF2122/97            LSARSAQALTNQARRLLAWVGAD-ENVRPLDVGWSLVNTRSLFDHRAVVV
Rv1661|M.tuberculosis_H37Rv         LSARSAQALTNQARRLLAWVGAD-ENVRPLDVGWSLVNTRSLFDHRAVVV
MMAR_2471|M.marinum_M               LAARSAPALVNQARRLAQWVSDR-PDLDVADVGWSLATTRSVFEHRAVVV
MAV_3109|M.avium_104                LSARSAEALTNQAARLLARVKAD-PGVRVLDVGWSLVSTRSRFEHRAVIV
MUL_2266|M.ulcerans_Agy99           VSAKSGSALGAQAARLAAHVRSH-DELDVADVGWSLAG-RSTFEHRAVVL
MLBr_00135|M.leprae_Br4923          VSGRSTAALMAQASRLAFYVQAD-PEVDPVDVGCALAA-RSVFEHRAVVV
TH_4621|M.thermoresistible__bu      LSSTSAEELRRTAGRLAEWVEAHTDEVVPADLAYTLARRRAHRPVRTTVI
                                    ::. :   *   * .               *:  :    *:    *:.::

MAB_0939|M.abscessus_ATCC_1997      VNTREAAVELLSAVADDRPA-PGLGRGESHDTPKTAWLFTGQGSQYPGMA
Mvan_0269|M.vanbaalenii_PYR-1       VNSAESAVELLGALADDRPA-PGLVRGESHDTPKTAWLFTGQGSQYPGMA
Mflv_0405|M.gilvum_PYR-GCK          VNTREAALDLLGALADDRPA-PGLVRGESHDTPKTAWLFTGQGSQYPGMS
MSMEG_0408|M.smegmatis_MC2_155      VNSRESAIELLGALADDRPA-PGLVRGESHEAPKTAWLFTGQGSQYPGMA
Mb1689|M.bovis_AF2122/97            GADRTQLMEGLTGLAAGVPG-ADVVAGRAQTVGKTAFVFPGQGAQWLGMG
Rv1661|M.tuberculosis_H37Rv         GADRTQLMEGLTGLAAGVPG-ADVVAGRAQTVGKTAFVFPGQGAQWLGMG
MMAR_2471|M.marinum_M               GADRTQLIQGLAGFVDGEPR-AGVVVGRARPVGKTVFVFPGQGSQWVGMG
MAV_3109|M.avium_104                GADGAQLLRRLADLAGGQPG-AGVVTGRAQPVGKTVFVFPGQGSQWPGMG
MUL_2266|M.ulcerans_Agy99           GADRDGLLAGLDELAGDEFGGASVIRGVAGAAGKTVFVFPGQGSQWIGMG
MLBr_00135|M.leprae_Br4923          GESREQLIAGLAGLAVGESG-AGVAIGQAAPLGKTVVVFPGQGAQRIGMG
TH_4621|M.thermoresistible__bu      ADGVEALTAGLREVADGDAP---YQPAVGMDDKAPVWVFSGQGSQWAGMG
                                              *  .. .         . .     .. :*.***:*  **.

MAB_0939|M.abscessus_ATCC_1997      RELFETEPVFADTLNRCAAAVADVLEKPLLDVIFDVD---GPEAEETLRQ
Mvan_0269|M.vanbaalenii_PYR-1       RELYDTEPVFAETLNRCAEAVADVLEKPLLDVIFDAE---ADDAEKTLQN
Mflv_0405|M.gilvum_PYR-GCK          RELFDTEPLFAETLRECAAAVDGMLEKPLLDVIFDTDGVLDTDSNETLRH
MSMEG_0408|M.smegmatis_MC2_155      RELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDAD-ELDGDTESPLRH
Mb1689|M.bovis_AF2122/97            AQLCATAPVFAEHIHRCERALREHVEWSLLDVLRGAP------GAPGLDR
Rv1661|M.tuberculosis_H37Rv         AQLCATAPVFAEHIHRCERALREHVEWSLLDVLRGAP------GAPGLDR
MMAR_2471|M.marinum_M               VDLLDTSTVFADQMHRCEKALAEYVSWSLLDVVRAVP------GAPGLNR
MAV_3109|M.avium_104                AQLLDRSTVFAEHMHRCARALAEHVDWSLIDVIRGAP------GAPGLDR
MUL_2266|M.ulcerans_Agy99           IELLDTAPVFARHIESCGQAFAEFVDWSLLDVLRGAA------GAPGLDR
MLBr_00135|M.leprae_Br4923          RELCSQLPVFAEEFDAVTGELDRHMRLPLRDVVWGAD------AG-LLDS
TH_4621|M.thermoresistible__bu      AELLATEQVFAAKIAEIEPLVARESGFSVTEAMTASET---------VTG
                                     :*     :**  .      .      .: :.:              :  

MAB_0939|M.abscessus_ATCC_1997      TSYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVGQYSAACVAEVFSLED
Mvan_0269|M.vanbaalenii_PYR-1       TCYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVGQYSAACVAGVFSLTD
Mflv_0405|M.gilvum_PYR-GCK          TSYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVGQYAAACVAGVLSLRD
MSMEG_0408|M.smegmatis_MC2_155      TTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVED
Mb1689|M.bovis_AF2122/97            VDVVQPALWAVMVSLAELWRSVGVVPDAVIGHSQGEIAAAYVAGALSLWD
Rv1661|M.tuberculosis_H37Rv         VDVVQPALWAVMVSLAELWRSVGVVPDAVIGHSQGEIAAAYVAGALSLRD
MMAR_2471|M.marinum_M               VDVVQPVLWAIMVSLAELWRSAGVLPDAVIGHSQGEIAAAYVAGALSLED
MAV_3109|M.avium_104                VDVVQPALWAVMVSLAELWRSVGVVPDAVIGHSQGEIAAACVAGALSLHD
MUL_2266|M.ulcerans_Agy99           IDVVQPVLFAVMVSLAELWKSVGVRPDAVIGHSQGEIAAAYVAGALSLRD
MLBr_00135|M.leprae_Br4923          TEFAQPALFAVEVALFAVLQHWGLQPDFVMGHSIGELAAAYVAGVLAPAD
TH_4621|M.thermoresistible__bu      IDRVQPTLFAIQVALAATMQSYGVRPGAVIGHSLGEVAAAVVAGALSLED
                                       .**.*:*: :.*    :  *. *. *:*** *: :** ** .:   *

MAB_0939|M.abscessus_ATCC_1997      GARLIAERGRLFSSLPAGGRMAAVFTDAERAERLTDEFPS--LSVAAYNG
Mvan_0269|M.vanbaalenii_PYR-1       GARLMAERGRLFGSLPEGGRMVAVFTTAERAEAMTDEFPS--LSVAAYNG
Mflv_0405|M.gilvum_PYR-GCK          GARLMAERGRLFGSLPSGGRMAAVFAAAERVEALTDEYPA--LSVAAYNG
MSMEG_0408|M.smegmatis_MC2_155      GARLIAERGRLFGSLPAGGRMAAVFTAPERAERLTDEYPS--LSVAAYNG
Mb1689|M.bovis_AF2122/97            AAAVVALRSRLLVRLGGAGGMVSLACGQPQAEKLASQWGDR-LNIAAVNG
Rv1661|M.tuberculosis_H37Rv         AAAVVALRSRLLVRLGGAGGMVSLACGQPQAEKLASQWGDR-LNIAAVNG
MMAR_2471|M.marinum_M               AARVVARRSQLLVQLSGAGGMVSLACGLERARQLVASWSDR-LSIAAVNG
MAV_3109|M.avium_104                AARVVALRSRLLVRLSGRGGMVSLACGRSRAEQLIAPWGER-LNIATVNG
MUL_2266|M.ulcerans_Agy99           AAKVVTLRSKLLVGLAGPGGMVSVACGEQQARELLEPFGDR-VSIAAING
MLBr_00135|M.leprae_Br4923          AAMLVVARGRLMQSMPAGGTMWAVAASE---DEVVSLLGEG-VGIAAINA
TH_4621|M.thermoresistible__bu      GVKVICRRSRLCLRLAGAGAMAAIELPAQAVREFLAARGVDDVVLSVIAS
                                    .. ::  *.:*   :   * * ::         .        : ::.  .

MAB_0939|M.abscessus_ATCC_1997      -ANTVLSGPAQDLEKAIAALVADGVRCDFLETSHAFHSALLDPILDEFEA
Mvan_0269|M.vanbaalenii_PYR-1       -TNTVLSGPAGDLEKAVATLSADGVRCDWLDTSHAFHSALLDPILDDFES
Mflv_0405|M.gilvum_PYR-GCK          -ANTVLSGPATDLERAVAGLVADGVRCDWLETSHAFHSALLDPILDDFES
MSMEG_0408|M.smegmatis_MC2_155      -ANTVLSGPAKDLESAVATLVADGVRCDWLDTSHAFHSALLDPILDDFES
Mb1689|M.bovis_AF2122/97            VSSVVLAGETDAVTELMQRCEAEGIRARRIDVDYASHSAQVDAIREELIA
Rv1661|M.tuberculosis_H37Rv         VSSVVLAGETDAVTELMQRCEAEGIRARRIDVDYASHSAQVDAIREELIA
MMAR_2471|M.marinum_M               VSAIVVSGEVDALDALIGRCEADDIRARRIDVDYASHSAQVEAIRAELAE
MAV_3109|M.avium_104                ISAVVVSGEVDALTELLDRCAADDIRARRIDVDYASHSVQVEEIRDSLAE
MUL_2266|M.ulcerans_Agy99           PSAVVVSGEVAALEELIAQCADRELRTRRIDVDYASHSVEVEAIEGQLTE
MLBr_00135|M.leprae_Br4923          PESVVISGPQAAVSAIADKFAAQGRRVHQLAVSHAFHSPLMEPMLEEFVR
TH_4621|M.thermoresistible__bu      PESTVIGGATDTVRELVAAWEAQGVMAREVAVDVASHSPQVDPILDELEE
                                        *:.*    :                : .. * **  :: :  .:  

MAB_0939|M.abscessus_ATCC_1997      YANQFNYKTPQRILIDNRTGTALGRSVKLDGAYWRRHARQPVEFAKSVRT
Mvan_0269|M.vanbaalenii_PYR-1       YANQFDFAAPQRILIDNRTGTALGRSVQLDGTYWRRHARQPVEFAKSVRT
Mflv_0405|M.gilvum_PYR-GCK          YARGITFTAPQRILIDNRTGAALGRSVTLDAAYWRRHARQPVEFAKSVHT
MSMEG_0408|M.smegmatis_MC2_155      FAQKLEYREPQRILIDNRTGSALGRSTRLDGAYWRRHARQPVEFAKSVRT
Mb1689|M.bovis_AF2122/97            ALRGIEPRTSTVAFFSTVTG-ELMDTAGVNAEYWYRSIRQPVQFERAVRN
Rv1661|M.tuberculosis_H37Rv         ALRGIEPRTSTVAFFSTVTG-ELMDTAGVNAEYWYRSIRQPVQFERAVRN
MMAR_2471|M.marinum_M               ALDGIAPQSTSTAFISTVTG-EFTDTAGLDADYWHRSIRQTVQFERAIRT
MAV_3109|M.avium_104                ALRGIAPRSSAVAFFSTVTG-ELMDTAALDGDYWFRSIRQTVQFERAVRG
MUL_2266|M.ulcerans_Agy99           VLAGIEPLSSRTAFFSSVTG-SRLDTAELDAEYWYRNIRQTVQFDQAVRS
MLBr_00135|M.leprae_Br4923          VAAQVEVRKPQIGLVSNVTG-ELAGPDFGSPQYWGEHVSRAVRFVDSARH
TH_4621|M.thermoresistible__bu      ILADLQPMTPTVPYYS-ATSYDPREKPVCDADYWVDNLRHEVRFAAAVQA
                                        .    .     .  *.         .  **     : *.*  : : 

MAB_0939|M.abscessus_ATCC_1997      LADMNCKVLLEIGPQPVLTAAALRAWPDP----ATAPRAIASLRRNTADH
Mvan_0269|M.vanbaalenii_PYR-1       LAEMNCKLLVEIGPRPVLTAAALGAWPDP----ATAPRVIASLRRTAADH
Mflv_0405|M.gilvum_PYR-GCK          LADMNCKLLVEIGPRPVLTAAALSAWPDP----ATSPRVIASLRRTTADQ
MSMEG_0408|M.smegmatis_MC2_155      LADMNCRVLLEIGPRPVLTATALAAWPDP----ATTPQVLASLRPTTADH
Mb1689|M.bovis_AF2122/97            AFDGGYRVFVESSPHPVLIAGIEETLVDCDRGATGEPIVIPTLGRDDGGV
Rv1661|M.tuberculosis_H37Rv         AFDGGYRVFVESSPHPVLIAGIEETLVDCDRGATGEPIVIPTLGRDDGGV
MMAR_2471|M.marinum_M               AFNSGCQVFIESSPHPVLMAGIEETLAGQQD--SGEAIVIPSLGRDDGGL
MAV_3109|M.avium_104                AAEAGYRAFIECSPHPVLTAAIEETMP-----DGGQGCVIPSLGRDDGGP
MUL_2266|M.ulcerans_Agy99           ACGHGYRTFIESSPHPALIAGIEDTYRNCAADSGADPIVVPTLGREDGGL
MLBr_00135|M.leprae_Br4923          LQTLGATHFIESGPSSGLMGAIEQSLAP------AEAVVVSMMGKDRPEL
TH_4621|M.thermoresistible__bu      ALEDGFRVFGELSPHPLLTRAVEQTARG----LDMPVAALPAMRREQEMP
                                        .   : * .* . *      :             .:. :       

MAB_0939|M.abscessus_ATCC_1997      RQITEAAADAYVLGHLPDFGAFQHA-PARKLDLPTYPFERRQYWFSDKRD
Mvan_0269|M.vanbaalenii_PYR-1       RQITEAVADAYVLGHLPEFGAFRDA-GARKLDLPTYPFEHRQYWFRDNQD
Mflv_0405|M.gilvum_PYR-GCK          RQITEAVADAYVLGHLPRFAAFRRD-GARVLDLPTYPFEHRQYWFSDSRE
MSMEG_0408|M.smegmatis_MC2_155      RQITEAVAAAYAAGHLPDFRAFRQP-DARKLDLPTYPFEHRQFWFSDNRA
Mb1689|M.bovis_AF2122/97            GRFWLSAGQAHVAGVGVDWRAAFADLGGRRVELPTYAFARQRFWLDGLGA
Rv1661|M.tuberculosis_H37Rv         GRFWLSAGQAHVAGVGVDWRAAFADLGGRRVELPTYAFARQRFWLDGLGA
MMAR_2471|M.marinum_M               QRFWLSVAQAHVAGVRVDWASIIG--AGRRVALPTYGFQHRRFWLGQLDA
MAV_3109|M.avium_104                DRFWLSAGQAFVSGVVVDWCAMLDGLGGRRVDLPTYGFVRQHFWLPGGST
MUL_2266|M.ulcerans_Agy99           QRFLASAAAAFVAGVNVDWRGPLD--GAGLVELPTYAFEKRRFWLSG-EG
MLBr_00135|M.leprae_Br4923          ASVLGAAGQLFATGMPVEWPAVFAGSSRRRVTLPTYAFQRRRFWETPGTD
TH_4621|M.thermoresistible__bu      HGVRTMVGDLFAAGAAVDFAALYPS--GRLVDAPLPTWTRRKLVLSRENG
                                      .   ..  .. *    : .         :  *   : :::        

MAB_0939|M.abscessus_ATCC_1997      GDNRDAGNRQQNNGGPRTEAVRLLEDGKIEELANLLGGVDGDQQTLNVLT
Mvan_0269|M.vanbaalenii_PYR-1       PD----GSEALQPRTPSTEAVRLLEDGRIEELATLLDGAAGDQQTLDVLS
Mflv_0405|M.gilvum_PYR-GCK          PV------AAAPQRGARTETVRLLEDGRIEELAALLGGTVDDPFTFDVLN
MSMEG_0408|M.smegmatis_MC2_155      IDRDTQTASAGSVTPHRTQAVRLLEDGQIEELAALIDGETVDEQTLRVLN
Mb1689|M.bovis_AF2122/97            VGGDLGGVGLVGAEHGLLAAVVQRPDS---------GGVVLTGRISVVAA
Rv1661|M.tuberculosis_H37Rv         VGGDLGGVGLVGAEHGLLAAVVQRPDS---------GGVVLTGRISVVAA
MMAR_2471|M.marinum_M               GRTDVGGLGQAGAAHGLLGAVVERPDS---------GGVVLTGQLSVALQ
MAV_3109|M.avium_104                GSSDVAALGLRGAEHGLLGAVLPRPDS---------GGVVLTGRLSTSAQ
MUL_2266|M.ulcerans_Agy99           VSVDASGLGLSAGGHALLGAVVELPES---------GGVVLTGRLALGAH
MLBr_00135|M.leprae_Br4923          GTASVSGLGLGSTEHALLGAVVERPDS---------GGVVLTGRLSLANQ
TH_4621|M.thermoresistible__bu      EQQTRG--GCTITVHPLLGTHVRLPEEP--------ERHVWQADLGTGAQ
                                                       :     :                        

MAB_0939|M.abscessus_ATCC_1997      KLAAQHNLQRTTQTIADDRYQFRWEKSPTPLSGSQAAGGVTWLLVADAAG
Mvan_0269|M.vanbaalenii_PYR-1       RLAAQHNQQRSSQSITNDRYEIRWEQSAAALSGAETDEVSSWILVGDDTE
Mflv_0405|M.gilvum_PYR-GCK          RLAAQHNQQRSTESIADDRYQIRWETAAEPPVGADAADGITWLLVGDDTD
MSMEG_0408|M.smegmatis_MC2_155      KLAARHNQQRSTHVDPDARYEIRWDAIAS--AAASTGAAADWILVGDDTA
Mb1689|M.bovis_AF2122/97            PWLADHAVGPVVLFPGTGFVELALRAGDEVGCSVLQELTLQAPLVLPADG
Rv1661|M.tuberculosis_H37Rv         PWLADHAVGPVVLFPGTGFVELALRAGDEVGCSVLQELTLQAPLVLPADG
MMAR_2471|M.marinum_M               PWLAGHAVAGTVLFPGAGFVELAIRAGDEVGCAAVEELTLSAPLVLPTVG
MAV_3109|M.avium_104                AWLADHAVGDTVLFPGAGFVELAIRAGDEVGCGVIDELTLSAPLPLPASG
MUL_2266|M.ulcerans_Agy99           GWLADHAVSGVVVFPGTGFVELAIRAVDEVGCSVVNELTLRTPLVLPASG
MLBr_00135|M.leprae_Br4923          PWLADHVIGGVVLFPGAGFVELVIRAGDEVGCAGVEELVLAAPLVLHPGS
TH_4621|M.thermoresistible__bu      PWLADHQIHTVAALPGAAYCEMALAAAREVIDSDGVEVRDVRFEQMLLLD
                                       * *              ::          .                 

MAB_0939|M.abscessus_ATCC_1997      AAQPLLDVLTARGQQHRVLALPVSDADEAELVEALRSAADEDSALRIVHV
Mvan_0269|M.vanbaalenii_PYR-1       ATRPLVDVLSARGQRYRIFGLPVSDADEEQLGEALRLAAAEDSTLRIVHV
Mflv_0405|M.gilvum_PYR-GCK          ATRPLVDVLAARGHRYRILGLPKSGAEEHELADTLRDAAADATDLRIVHV
MSMEG_0408|M.smegmatis_MC2_155      AVLEFADALTAGGHRHQIVALPGSDADEAQLVDTLRAASAG--ELYVVHI
Mb1689|M.bovis_AF2122/97            -VRVQVVVGGVEQSGTRNVWVYSAAG---QADSSPGWTLHAQGVLGVGSV
Rv1661|M.tuberculosis_H37Rv         -VRVQVVVGGVEQSGTRNVWVYSAAG---QADSSPGWTLHAQGVLGVGSV
MMAR_2471|M.marinum_M               GVQLQVVVGPADQSDHRTVEVYSRGD---QSLS--EWSLHAEGVLAPAAV
MAV_3109|M.avium_104                GVRLQLVVGAPDEAGRRPLSVYSAAA---HQDS--EWMLHAEGVLRTGTV
MUL_2266|M.ulcerans_Agy99           SVAVQVVVGAAADSAERSVSIYSRTDTDTDTDAGSVWVCHAEGTLGADSA
MLBr_00135|M.leprae_Br4923          GVQVQVVVAAADESSRRAVSVYSRGD-----QSHGGWLLNAEGLLEVDAA
TH_4621|M.thermoresistible__bu      EQTEVSAVASAVEPGTLEFAVETAKD-----GEHERRATAVLGAADDTEP
                                           .          . :                             

MAB_0939|M.abscessus_ATCC_1997      AALAGQ----GSSSAQSLLRIQHQVLGGTRRLFRAAAAAELRAPIWIVTR
Mvan_0269|M.vanbaalenii_PYR-1       GGLDSDPDPGTAPSMRSLLRMQHRILGGTRRLFRAAAAAELRTPIWVVTR
Mflv_0405|M.gilvum_PYR-GCK          AALDAA---ESDTSMKSLLRMQHRVLGGTRRLFGAAVAAQLRSPMWLVTR
MSMEG_0408|M.smegmatis_MC2_155      AAGDGA-----AAPMRDLLRVQHRTLGGLRRLFRAANDAELRSPIWLVTR
Mb1689|M.bovis_AF2122/97            QPAAELSVWPPVGARAMDVADGYQVLAARG----YGYGPAFRGLQALWRR
Rv1661|M.tuberculosis_H37Rv         QPAAELSVWPPVGARAMDVADGYQVLAARG----YGYGPAFRGLQALWRR
MMAR_2471|M.marinum_M               ASVGQLTAWPPEGATALDLGGVYDRLAARG----YEYGPAFRGLQAVWES
MAV_3109|M.avium_104                TPAGDLSIWPPIGATAVDVTGGYARLAQRG----YEYGRAFRGLRAMWQR
MUL_2266|M.ulcerans_Agy99           QPAADLSAWPPAGAIAVDVADGYERLDARG----YGYGPAFRGLTAMWAR
MLBr_00135|M.leprae_Br4923          EATVDLSLWPPEGAESVDISDAYPQLAERG----YAYGPAFQGLVAIWRR
TH_4621|M.thermoresistible__bu      PQAHDIDALLAEHPTRIEGDELRQWFDQRG----VQFGPAFTGLTAARIP
                                                 .           :              :         

MAB_0939|M.abscessus_ATCC_1997      G---AQHVIEGDTVAPEQSALWGFGRAAALELPQVWGGLADLSDAGTDEW
Mvan_0269|M.vanbaalenii_PYR-1       R---AQHVTATDTVAPDQSCLWGFGRAAALELPQLWGGLADLADGTADEW
Mflv_0405|M.gilvum_PYR-GCK          G---AQHVTDTDVVAPDQTCLWGFGRAASLEHPQIWGGLADLGGGTSDEW
MSMEG_0408|M.smegmatis_MC2_155      D---GQRVTDTDTVVPEQSCLWGFGRAAALELPHIWGGLADLSG-ADTEW
Mb1689|M.bovis_AF2122/97            G---AEVFADVTLPE--GVPIRGFGIHPAVLDAALHAWGIVEG----EQQ
Rv1661|M.tuberculosis_H37Rv         G---AEVFADVTLPE--GVPIRGFGIHPAVLDAALHAWGIVEG----EQQ
MMAR_2471|M.marinum_M               G---DEIFAEVALPEDAGAQIGGFGIHPALLDAALHALVLTAE----QNQ
MAV_3109|M.avium_104                G---DEIFAEVALPDD-AAAGDDFGVHPVLLDAALHALGVAGE----KDQ
MUL_2266|M.ulcerans_Agy99           G---EELFAEARLPEA-AGSTSGFGVHPALLDAALHTAVIANP----DAD
MLBr_00135|M.leprae_Br4923          G---SELFAEVVAPTG--VVVDGMGMHPALLDAVLHALGLAIENTQATTE
TH_4621|M.thermoresistible__bu      EGTVTSVLAEVGLPGQIRSQQAPYGIHPALLDACFQSVAAHPDVQGAGSG
                                         . .                *  . :  . .               

MAB_0939|M.abscessus_ATCC_1997      AQFIGRVSVSGEA----STREDQLALRGQAVHVPRLVRREELPSGKP-LE
Mvan_0269|M.vanbaalenii_PYR-1       SRLLNRITAPHGP----AVREDQIALRDHAVYVPRLVRRAGRPAGKP-LQ
Mflv_0405|M.gilvum_PYR-GCK          SRLLNRIAATHDP----AVMEDQVAVRGSTSYVPRLVHRDTLPSGKP-LH
MSMEG_0408|M.smegmatis_MC2_155      PRLIARITSPRD-------GEDQIALRGDAVYAPRLVRRTGEPSDTP-LP
Mb1689|M.bovis_AF2122/97            TMLPFSWQGVCLH----ASGAARVRVRLAPVGRGAVPVELADPQGLPVLS
Rv1661|M.tuberculosis_H37Rv         TMLPFSWQGVCLH----ASGAARVRVRLAPVGRGAVSVELADPQGLPVLS
MMAR_2471|M.marinum_M               TVLPFAWQGVSLH----AAGASRCRVRIAQSRSGSVAMELADSAGLPVLT
MAV_3109|M.avium_104                TVLPFSWQGVALH----ASGASRARVRIAPAGAGAVSVELADGAGLPVLS
MUL_2266|M.ulcerans_Agy99           LVLPFSWQGVSLH----AAGAASVRVRIAPVGPSSVSVELADDLGLPVLS
MLBr_00135|M.leprae_Br4923          MRLPFCWRGVSLH----AGGAGRVRARFTSAGADAIAVDIADSAGLPVLT
TH_4621|M.thermoresistible__bu      LLLPLGVRRLQAFGPTRGARYCYARVTDADGSKAEADLDVLDEHGNVLLR
                                      :                                         .   * 

MAB_0939|M.abscessus_ATCC_1997      VRSDATY------------------------------------------L
Mvan_0269|M.vanbaalenii_PYR-1       LRDDATY------------------------------------------L
Mflv_0405|M.gilvum_PYR-GCK          LRADATY------------------------------------------L
MSMEG_0408|M.smegmatis_MC2_155      VREDRTY------------------------------------------L
Mb1689|M.bovis_AF2122/97            VRQLMVR------------------------------------------P
Rv1661|M.tuberculosis_H37Rv         VRQLMVR------------------------------------------P
MMAR_2471|M.marinum_M               VRDLAFR------------------------------------------P
MAV_3109|M.avium_104                VRSVTMR------------------------------------------P
MUL_2266|M.ulcerans_Agy99           VKAMVAR------------------------------------------P
MLBr_00135|M.leprae_Br4923          VRSLVTR------------------------------------------A
TH_4621|M.thermoresistible__bu      VQGLLMGGAAADGDDRDRVLGERLLTIEWQRRDLPEADSAAGKWLLVSTS
                                    ::                                                

MAB_0939|M.abscessus_ATCC_1997      VTGGLGSIGLEIAGYLAGRGAKHLVLTSRREPGEAARQR-----------
Mvan_0269|M.vanbaalenii_PYR-1       VTGGLGSIGLEIAGYLAAHGARHLVLTSRRAPGDATQQR-----------
Mflv_0405|M.gilvum_PYR-GCK          VTGGLGSLGLEIAGYLAANGAGHLVLTSRRTPDEAAASR-----------
MSMEG_0408|M.smegmatis_MC2_155      VTGGLGAIGLEVAGYLASHGAGHVVLTSRREPGDDARRR-----------
Mb1689|M.bovis_AF2122/97            VS--AAALSRSTAG---DRGLLEMIWTPVPLEGGDIGDD-----------
Rv1661|M.tuberculosis_H37Rv         VS--AAALSRSTAG---DRGLLEMIWTPVPLEGGDIGDD-----------
MMAR_2471|M.marinum_M               VS--DQTSSAGTAG---GGGLLEVVWSPLARPGDDTADIP----------
MAV_3109|M.avium_104                VSPGQLSAAMGTAQ---PSGLLDVIWSPIALGGNDLGDE-----------
MUL_2266|M.ulcerans_Agy99           VSEQQMRAVVSASG---PDRLFEVVWTPMTVAATDAAPAY----------
MLBr_00135|M.leprae_Br4923          MTAEQLRTAVTAAGGALEQGPMDLVWSPIPLSSDGHGGGLPSVVSWADYC
TH_4621|M.thermoresistible__bu      ATADVSATRLSDALKQAGAESTSMCWPQQADHADNVDRFRAGIADG----
                                     :          :          :  .                       

MAB_0939|M.abscessus_ATCC_1997      -------IDALAAQG-CEVRAVTADVADGHDVARLLAGIQAELPPLAGIV
Mvan_0269|M.vanbaalenii_PYR-1       -------IDALGAQHSCQIRVVAADVADAHDVARLLAAVAAELPPLAGIV
Mflv_0405|M.gilvum_PYR-GCK          -------IEALRERHGCEVRVVTADVADAHAVARLLATVQAEMPPLAGIV
MSMEG_0408|M.smegmatis_MC2_155      -------LDGLREQYACDVRVITADVADAHDVARLMTTVAAELPPLAGIV
Mb1689|M.bovis_AF2122/97            --------AVVWELPPHAG-AQAGGDVLAAVYRGVHEVLEVLQSWLASDA
Rv1661|M.tuberculosis_H37Rv         --------AVVWELPPHAG-AQAGGDVLAAVYRGVHEVLEVLQSWLASDA
MMAR_2471|M.marinum_M               --------VTLWDLASQVE-LSAG--AVESTYVATHGALGALQSWLASDQ
MAV_3109|M.avium_104                --------VTLWEPG------EHGGDVVKSVHAAVTETLAVLQSWLDGEG
MUL_2266|M.ulcerans_Agy99           --------ELFESIA-------ADGDPLSGTYQRTHQALAAVQSWLTEHD
MLBr_00135|M.leprae_Br4923          AGRGNDTGVVVWEFGSASAGAQAPVDSVAAVYSATHAALQVLQFWFGQDR
TH_4621|M.thermoresistible__bu      ------VTGVVVLTGPKNGNPDDAAARRGSDYVRHLVRITRELAEIDGDA
                                              .                           :      :    

MAB_0939|M.abscessus_ATCC_1997      HAAGEIGTTPLSDLEDAEVDRVFAGKVWGAWHLSEAAA-GLK--LDFFIN
Mvan_0269|M.vanbaalenii_PYR-1       HAAGEIGTTPLVSLEDSEVDRVFAGKVWGAWHLSEAAA-DLQ--LDFFLG
Mflv_0405|M.gilvum_PYR-GCK          HAAGEIGTTPLADLDDAEVDRVFAGKVWGAWHLSEATS-DLQ--LDFFIS
MSMEG_0408|M.smegmatis_MC2_155      HAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEALT-DLRTDLDFFVS
Mb1689|M.bovis_AF2122/97            TGLGVVVTRGAVGPVDDDVTDLAGAAVWGLVRSAQAEH-PGRVVLVDTDG
Rv1661|M.tuberculosis_H37Rv         TGLGVVVTRGAVGPVDDDVTDLAGAAVWGLVRSAQAEH-PGRVVLVDTDG
MMAR_2471|M.marinum_M               PGVLAVVTHGAVGLADEDVTDLAGSAVWGLVRSAQAEH-PGRVVLVDTDG
MAV_3109|M.avium_104                AGVLAVQTHGAVALAGEDVSDLAGAAVWGLVRSAQAEH-PGRLVLIDSDG
MUL_2266|M.ulcerans_Agy99           SGVLVVATRGAMALAGEDVTDLAGAAVWGLVRSAQTEN-PGRLVLVDSDA
MLBr_00135|M.leprae_Br4923          AGTLVVLTRGAVGLVGEGISDLAAAAVWGMVRSAQSEH-SGKIVLIDTDS
TH_4621|M.thermoresistible__bu      P-RLFVVTRGAQAVLPQDRPNLEQAGLRGLLRVIGAEHPHLRTTQIDIAD
                                         : *             :  . : *  :   :     :        

MAB_0939|M.abscessus_ATCC_1997      TSSIAAVWG----GYGQTAYSAANAFLDGLAWRLREQG--IAGTSVNFGP
Mvan_0269|M.vanbaalenii_PYR-1       TSSIASVWG----GYGQTAYGAANAFLDGLAWRLREQG--ISGVSINFGP
Mflv_0405|M.gilvum_PYR-GCK          TSSIASVWG----GFGQAAYGAANAFLDGLAWRLREQG--VAGVSVNFGP
MSMEG_0408|M.smegmatis_MC2_155      TSSIASVWG----GFGQTAYGAANAFLDGLAWRLRERG--VTAVSVNFGP
Mb1689|M.bovis_AF2122/97            SVAVEDAVGFGA-RSGEPQLVVRRGRVYAARLAPVAAG--LTLPSASAGG
Rv1661|M.tuberculosis_H37Rv         SVAVEDAVGFGA-RSGEPQLVVRRGRVYAARLAPVAAG--LTLPSASAGG
MMAR_2471|M.marinum_M               SVELGAVL-----NSGEPQLVVRAGVAYQARLKPAESL--LRLPPPGEN-
MAV_3109|M.avium_104                SLDARAVIP-----CGEPQVVVRQGVAHAARLRPARAG--ATLG-LPSGA
MUL_2266|M.ulcerans_Agy99           AVDAAAVAT-AL-AVGEPQVVLRNGQPYTARVHASRAAD-GILVPPVDGP
MLBr_00135|M.leprae_Br4923          AVDVAVLAD-----LGESQLLVRCNTVHAARLSPAPQL---LALPVGESM
TH_4621|M.thermoresistible__bu      DADLDRVAVQLLGGGAEDETAWRDGQWYTARLSLSPLRPEERKQAVVDCE
                                                   .:                                 

MAB_0939|M.abscessus_ATCC_1997      WSAGMADAESRARLEQRGIKTLSPTDALAGLADVVAASGS-NAVQGVIAR
Mvan_0269|M.vanbaalenii_PYR-1       WSAGMADAESRARLDQRGVRTLSPADALAGLADVVTAAEAPGPAQGIVAR
Mflv_0405|M.gilvum_PYR-GCK          WSAGMADAQSRARLEQRGIKTLSPADALAGLSDAVISAAP----HPVVAR
MSMEG_0408|M.smegmatis_MC2_155      WAAGMADAESRARLEQRGVRTLSPAEALAGMADVVAGPVQ-----GVVAK
Mb1689|M.bovis_AF2122/97            WRLVAGGGGTLADVVVAPVAPV---ELATGQVRVAVGAVG-------VNF
Rv1661|M.tuberculosis_H37Rv         WRLVAGGGGTLADVVVAPVAPV---ELATGQVRVAVGAVG-------VNF
MMAR_2471|M.marinum_M               WRLVTGGGGTLDDVKVGGCAPS---GLMTGQLRVAVAAVG-------VNF
MAV_3109|M.avium_104                WRLDAGGEGTLGDLVVSRCPRT---ELADGQVRVAVAAVG-------VNF
MUL_2266|M.ulcerans_Agy99           WRLGLSSAGTFENLQLEPVPNAG-APLGPGQVRVAMRAIA-------ANF
MLBr_00135|M.leprae_Br4923          WRLAADGGGTLEDLVIQPCPEVQ-APLQAGHMRVAVAAVG-------VNF
TH_4621|M.thermoresistible__bu      RDGMRLEIRTPGDLETMELAAFDRVPPGPGQIEVAVTASS-------INF
                                             :   :               *   ..  .            

MAB_0939|M.abscessus_ATCC_1997      IDWARFLPLYQQAGKRGFLAELDREVPSHLAGV--AGAQSGSTQLVERLA
Mvan_0269|M.vanbaalenii_PYR-1       IDWERFLPLYQQAGRRAFLAELEREVPDTAP----AATPSGRTELVERLT
Mflv_0405|M.gilvum_PYR-GCK          VDWSRFLPLYQQAGRRGFLAELERELPAAPAQQGPAVTASGRTPLVERLT
MSMEG_0408|M.smegmatis_MC2_155      IDWSRFLPLYQQAGRRAFLSELESELPAAATGAAAPATVPGKPPLVEQLT
Mb1689|M.bovis_AF2122/97            RDVLVALGMYPGGGE---------------------LGVDGAGVVVEVGP
Rv1661|M.tuberculosis_H37Rv         RDVLVALGMYPGGGE---------------------LGVDGAGVVVEVGP
MMAR_2471|M.marinum_M               RDVLVALGMYPGGGE---------------------LGVEGAGIVTEVGP
MAV_3109|M.avium_104                RDVLVALGMYPGGGR---------------------LGAEGAGVVVEVGP
MUL_2266|M.ulcerans_Agy99           RDIMITLGMFTHDAL---------------------IGGEGAGVVVEIGP
MLBr_00135|M.leprae_Br4923          RDVVAALGMYPGQAPP--------------------LGAEGAGVVIEIGP
TH_4621|M.thermoresistible__bu      ADVLIAFGRYPTFDGRR-----------------PQLGTDFAGVVTAVGP
                                     *    :  :                                  :    .

MAB_0939|M.abscessus_ATCC_1997      NAPVQQRKKLLTDYLRDAVAEVTRVDVSEIREDAGFFDLGMDSLMAVELR
Mvan_0269|M.vanbaalenii_PYR-1       NAPVQQRKKLLTDYLRTAVAEITRVDATEIREDAGFFDLGMDSLMAVELR
Mflv_0405|M.gilvum_PYR-GCK          TAPLQQRKRLLTDYLRDAVAEVTRVDAAEIREDAGFFDLGMDSLMAVELR
MSMEG_0408|M.smegmatis_MC2_155      KAPVQQRKSLITNYLRNAVAEVTRVDADEIRDEAGFFDLGMDSLMAVELR
Mb1689|M.bovis_AF2122/97            GVTGLAVGDRVMGLLG-LVGSEAVVDARLVTMVP----------------
Rv1661|M.tuberculosis_H37Rv         GVTGLAVGDRVMGLLG-LVGSEAVVDARLVTMVP----------------
MMAR_2471|M.marinum_M               GVSGVAVGDAVMGLLG-VVGPEAVVDHRLVTAVP----------------
MAV_3109|M.avium_104                AVTGLAVGDPVMGLLG-VVGSEAVVDQRLLTAVP----------------
MUL_2266|M.ulcerans_Agy99           EVTEFAVGDAVYGFFPDGSGTLVAGDVRLLLPKP----------------
MLBr_00135|M.leprae_Br4923          EVTGVAVGDAVMGFLG-GAGPLAVVHQQLITQMP----------------
TH_4621|M.thermoresistible__bu      DVTSHRVGDRVGGLSPNGCWSTFVTCDADLAVPLP---------------
                                     ..       : .                :                    

MAB_0939|M.abscessus_ATCC_1997      RRMEQGVGKEIPVTLVMDHPRISDVADYLLGDVLGLAEQA--KPAAQLAS
Mvan_0269|M.vanbaalenii_PYR-1       RRIEQGVGREIPATLAMDHPRLSDVADYLLGEVLGLAEQAPAKAGSQPAS
Mflv_0405|M.gilvum_PYR-GCK          RRIETGVGKEIPVTLVMDHPRLSDAADYLLGDVLGLTEAA---TAPKAAT
MSMEG_0408|M.smegmatis_MC2_155      RRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEVLGLGEQT----NVRQAS
Mb1689|M.bovis_AF2122/97            AGWSLVEAAAVPVAFLTAFYGLSVLAEVAAGQKVLVHAGTG---------
Rv1661|M.tuberculosis_H37Rv         AGWSLVEAAAVPVAFLTAFYGLSVLAEVAAGQKVLVHAGTG---------
MMAR_2471|M.marinum_M               PGWSLQTAASVPVVFLTAFYGLRVLAEVRSGQKLLVHAATG---------
MAV_3109|M.avium_104                PGLSLVAAAGVPVVFLTALYGLSVLSGLRPGERVLVHTATG---------
MUL_2266|M.ulcerans_Agy99           ADWSYAEAAAISAVFTTAYYAFVHLANVQPGQRVLVHAATG---------
MLBr_00135|M.leprae_Br4923          QGWSLAEAAAVPVVFLTALFGLADLAGIRAGESVLIHAGTG---------
TH_4621|M.thermoresistible__bu      DGLTEGQAAAVSTAHATAWYGLHDLARLGAGEKVLIHSATG---------
                                           .  :...       :   :     : : :   :          

MAB_0939|M.abscessus_ATCC_1997      AVTGRTDEPIAIVAVSCRFPGAPDPEAFWDVLS-GGVDAIREVPEDRFDI
Mvan_0269|M.vanbaalenii_PYR-1       AAANRTDEPIAIVAVSCRFPGAPDPEAFWEVLA-GGVDAIREVPEDRFDI
Mflv_0405|M.gilvum_PYR-GCK          VVSTAADEPIAIVAVSCRFPGAPNPEAFWDLLS-GGVDAIREVPEDRFDI
MSMEG_0408|M.smegmatis_MC2_155      TVTARTDDPIAVVAVSCRFPGAPDPESFWELLA-GGVDAIREVPEDRWDI
Mb1689|M.bovis_AF2122/97            ----------GVGMAAVSLARYWGAEVFVTASR-AKWDTLRAMGFDDIHI
Rv1661|M.tuberculosis_H37Rv         ----------GVGMAAVSLARYWGAEVFVTASR-AKWDTLRAMGFDDIHI
MMAR_2471|M.marinum_M               ----------GVGMAAVQLARLWGLEVFATASP-GKWDTLRAMGFDDDHI
MAV_3109|M.avium_104                ----------GVGMAAVQLARHYGAEVFATASR-GKWDTLRAMGFDDDHI
MUL_2266|M.ulcerans_Agy99           ----------GVGMAAVQLARHLGLEVYATASK-GKWDILRAMGFDEDHI
MLBr_00135|M.leprae_Br4923          ----------GVGMAAVQFARHWGVEIFVTASR-GKWDTLRDMGFDDDHI
TH_4621|M.thermoresistible__bu      ----------GVGLAAIAIARSVGAQIYATAGSPARRDLLRDMG--IEHV
                                              .:  .:  :.   . : :      .  * :* :     .:

MAB_0939|M.abscessus_ATCC_1997      DEFYDPDPEVAGKTYTRFGGFLDGIDGFDPEFFGISPREAVWIEPQQRLM
Mvan_0269|M.vanbaalenii_PYR-1       DEFYDPDPDAAGKTYTRFGGFLDGIDGFDPEFFGISPREAVWIEPQQRLM
Mflv_0405|M.gilvum_PYR-GCK          DEFYDPDPDAAGKTYTRYGGFLDHIDEFDPEFFGLSPREAVWIEPQQRLM
MSMEG_0408|M.smegmatis_MC2_155      DEFYDPDPDTPGKTYTRFGGFLDGIDGFDPEFFGISPREAVWIEPQQRLM
Mb1689|M.bovis_AF2122/97            SDSRSLEFEEAFLRATEGSGVDVVLNSLAGEFTDASLR----LLPSGGRF
Rv1661|M.tuberculosis_H37Rv         SDSRSLEFEEAFLRATEGSGVDVVLNSLAGEFTDASLR----LLPSGGRF
MMAR_2471|M.marinum_M               ANSRTLEFEEKFRAGTGGVGVDAVLNSLAGEFVDASLR----LLVPGGRF
MAV_3109|M.avium_104                GDSRSPDFEQKFLAATGGAGVDVVLNSLAGEFTDASLR----LLAPGGRF
MUL_2266|M.ulcerans_Agy99           SDSRSLEFEEKFREVTGGRSVDVVLDSLAGEFVDASLR----LLGPGGVF
MLBr_00135|M.leprae_Br4923          GDSRTLEFEEKFLAVTDGRGVDVVLDSLAGDFVDASLR----LLVRGGRF
TH_4621|M.thermoresistible__bu      YDSRSTAFADEIRRDTDGYGVDVVLNSLPGAAQRAGLE----LLSFGGRF
                                     :             *   ..   :: :       . .    :      :

MAB_0939|M.abscessus_ATCC_1997      LETVWEGLE-RAGYSPAALRGSRTGIFAGVGAN-EYAHLLSSESIDKIEP
Mvan_0269|M.vanbaalenii_PYR-1       LETVWEGLE-RAGLAPADLRGSRTGIFVGVAAN-EYAHLLSSESIEKIEP
Mflv_0405|M.gilvum_PYR-GCK          LETVWEGLE-RAGYAPSALRGSRTGVFVGVAAN-EYAHLLSAESIDKIEP
MSMEG_0408|M.smegmatis_MC2_155      LETVWEGLE-RAGYAPSDLRGSRTGVFTGVAAN-EYAHLLSAESIDKIEP
Mb1689|M.bovis_AF2122/97            IELGKTDIR-DGQTVAERHRGVRYRAFDLVEAGPDRIAAMLSEVVGLLAA
Rv1661|M.tuberculosis_H37Rv         IELGKTDIR-DGQTVAERHRGVRYRAFDLVEAGPDRIAAMLSEVVGLLAA
MMAR_2471|M.marinum_M               IEMGKTDLR-DPQTMAEQHRGVGYRAFDLIEAGPDLIARMLAELSRLLCA
MAV_3109|M.avium_104                IEMGKTDVR-DPDVVAQRYRGARYRAFDLMEAGPDRTAAMLAEIVGLLRA
MUL_2266|M.ulcerans_Agy99           LEMGKTDIR-DPGVIAQEYPGVRYRAFDLFEPGRPRMHQYMLDLAGLFDA
MLBr_00135|M.leprae_Br4923          LEMGKTDIR-DAQEIAANYPGVQYRAFDLSEAGPVRMQEMLCEVRELFDT
TH_4621|M.thermoresistible__bu      IEIGKRDIYGDTRLGLFPFRRNLAFHGVDLGLMADSHPHKIRELLETVYR
                                    :*    .:                                  :    .  

MAB_0939|M.abscessus_ATCC_1997      YFITGNALNAISGRVAFALGFEGPAVAVDTACSSALVAVHQAVQALHSGD
Mvan_0269|M.vanbaalenii_PYR-1       HFITGNALNAISGRVAFALGLEGPAVAVDTACSSALVAVHQACQALHSGD
Mflv_0405|M.gilvum_PYR-GCK          HFITGNALNAISGRVAFALGLEGPAVAVDTACSSSLVAVHQATQALRSGD
MSMEG_0408|M.smegmatis_MC2_155      HFITGNALNAISGRVAFALGFEGPAVAVDTACSSALVAVHQACQALQSGD
Mb1689|M.bovis_AF2122/97            GVLARLPVKTFDARCAPAA----YRFVSQARHIGKVVLTIPDGPGGQSG-
Rv1661|M.tuberculosis_H37Rv         GVLARLPVKTFDARCAPAA----YRFVSQARHIGKVVLTIPDGPGGQSG-
MMAR_2471|M.marinum_M               ETLTPLPIKTFDVRLARQA----YRFVSQARHIGKVVLTLPDETGAVPAG
MAV_3109|M.avium_104                GVLTPLPLKTFDVRCASTA----YRYVSQARHIGKVVLTVPSGPGEVLSG
MUL_2266|M.ulcerans_Agy99           GVLRPLPVTAFDVRRAPAA----LRYLSQARHVGKVVMTMPADQGGALG-
MLBr_00135|M.leprae_Br4923          QVLHRLPVTSWDVRCAPAA----FRFMSQARHIGKVVLTMPSALADGLA-
TH_4621|M.thermoresistible__bu      LTADGVLPMPQSTHYPLAEAATAIRVMSAAEHVGKLVLDVPHT-------
                                             . . : .             :   . :*             

MAB_0939|M.abscessus_ATCC_1997      CDLALAGGVNVLLSPVTVIAASRARMLSPVGRCKTFDASADGYVRSEGCG
Mvan_0269|M.vanbaalenii_PYR-1       CDLALAGGVNVLLSPVTSVAASRARMLSPVGRCKTFDASADGYVRSEGCG
Mflv_0405|M.gilvum_PYR-GCK          CDMALAGGVNVLLSPVTVVAASRARMLSPVGRCKTFDASADGYVRSEGCG
MSMEG_0408|M.smegmatis_MC2_155      CDLALAGGVNVLLSPVTVVAASRARMLSPVGRCKTFDASADGYVRSEGCG
Mb1689|M.bovis_AF2122/97            ----LAGGTVVVTGGTGMAGSAVATHLVRRHGVANLVLVSRSGEQADRA-
Rv1661|M.tuberculosis_H37Rv         ----LAGGTVVVTGGTGMAGSAVATHLVRRHGVANLVLVSRSGEQADRA-
MMAR_2471|M.marinum_M               A---LAGGTVIITGGTGMAGTALARHVVSRHRVANVILVSRSGAQAEGT-
MAV_3109|M.avium_104                CGGGLAQSTVLITGGTGMAGSALARHLVDRYRVGHVVLVSRTGAQAAGA-
MUL_2266|M.ulcerans_Agy99           ------GGTVLITGGTGMAGSALARHLVAHHGVAHLVLISRRGPAAPGA-
MLBr_00135|M.leprae_Br4923          ------EGTVLITGASGAIGGVLARHMVSAYGVRHLVLASRRGDRAEGA-
TH_4621|M.thermoresistible__bu      ------GRADVVVPPEQASPFRSDGAYIVTGGMGGLGLYLAGEMAAAGAG
                                            . ::                       .         :    

MAB_0939|M.abscessus_ATCC_1997      ILVLKRLSDAERDGDRVLAVIPGSAVNQDGASSGLTVPNGGAQQRLIGSV
Mvan_0269|M.vanbaalenii_PYR-1       ILVLKRLGDAVRDGDRVCAVIPSSAVNQDGASSGLTVPNGGAQQRLIGMA
Mflv_0405|M.gilvum_PYR-GCK          ILVLKRLSDAVRDGDRVCAVIAGSAVNQDGASSGLTVPNGGAQQRLIGTV
MSMEG_0408|M.smegmatis_MC2_155      VLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGGAQQRLIEAT
Mb1689|M.bovis_AF2122/97            ----AEVAALLREGGAQVAVVSCDVADRD-ALAALLAGLDPRYP-LKGVF
Rv1661|M.tuberculosis_H37Rv         ----AEVAALLREGGAQVAVVSCDVADRD-ALAALLAGLDPRYP-LKGVF
MMAR_2471|M.marinum_M               ----SELLGQLQDAGAEAAVVACDVSDRD-AVAELLAQVPARYP-LRGVI
MAV_3109|M.avium_104                ----AELVDELQRAGASASVLACDVGDRD-AVATMLAGLPSGYP-LRGIV
MUL_2266|M.ulcerans_Agy99           ----TELVAELSAAGAQVEVVACDAADRP-ALAKVIAENPAQRP-LSAVV
MLBr_00135|M.leprae_Br4923          ----VELAAELVGAGAKIQVVACDVADND-AVRGLFAQLSREFPPVRGVI
TH_4621|M.thermoresistible__bu      -----CIVLNGRSAPSGEALRTIEQLRAAGTEVIVECGXXXRGQPVEVAV
                                          :      .     : . .      :   :          :    

MAB_0939|M.abscessus_ATCC_1997      LARAGLVGGDVDYLEAHGTGTPLGDPIEVQAAAAAYGGSRDADRPLLMGS
Mvan_0269|M.vanbaalenii_PYR-1       LARAGLSGGDVDYLEAHGTGTPLGDPIEVQAAAAAYGASRDADRPLLMGS
Mflv_0405|M.gilvum_PYR-GCK          LARAGITGGEVDYLEAHGTGTPLGDPIEVQAAAAAYAGARDADRPLLMGS
MSMEG_0408|M.smegmatis_MC2_155      LARAGLSGADVDYLEAHGTGTPLGDPIEVQAAAAAYGAGRDADRPLLMGS
Mb1689|M.bovis_AF2122/97            HAAGVLDDAVITGLTPDRVDTVLRAKVDGAWNLHELTEDMDLSAFVVFSS
Rv1661|M.tuberculosis_H37Rv         HAAGVLDDAVITGLTPDRVDTVLRAKVDGAWNLHELTEDMDLSAFVVFSS
MMAR_2471|M.marinum_M               HAAGVLDDGLIASLTPQRVDTVLRAKIDGAWNLHELTRGLNLSAFVLFSS
MAV_3109|M.avium_104                HAAGILDDGLLSSLTPDRVDAVLRAKVDGAWNLHELTKDLDLSAFVVFSS
MUL_2266|M.ulcerans_Agy99           HAGGVLDDAVISSLTPERVDTVLRAKVDAAWNLHELTRDLDLSAFVMFSS
MLBr_00135|M.leprae_Br4923          HAAGVLDDGAITSLTPDRVDTVLRAKVDAAWNLHEATRDLDLLMFVLCSS
TH_4621|M.thermoresistible__bu      PTELRHADEHPDRRGAQLCDEFARGEQGAQRNQHRTDAGEGQRDAHPPGA
                                     :     .       ..  .                    .       .:

MAB_0939|M.abscessus_ATCC_1997      VKSNIGHTESASGAAGLIKVVLSLQNGVLPQSLHFDNPSPHIPWESLPVR
Mvan_0269|M.vanbaalenii_PYR-1       VKTNIGHLESASGAAGLIKVVLSLQHNLLPQSLHFENPSPHIPWDSLPVR
Mflv_0405|M.gilvum_PYR-GCK          VKTNIGHTESASGAAGLIKVVLSLQHETLPQSLHFDTPSPHIPWDSLPVR
MSMEG_0408|M.smegmatis_MC2_155      VKTNIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVR
Mb1689|M.bovis_AF2122/97            MAGIVGTPAQGNYAA-----ANAFLDGLVAYRRSRGLAGLSVAWG-LWEQ
Rv1661|M.tuberculosis_H37Rv         MAGIVGTPAQGNYAA-----ANAFLDGLVAYRRSRGLAGLSVAWG-LWEQ
MMAR_2471|M.marinum_M               MAGIIGTAGQGNYAA-----ANSFLDGLAVHRRALGLPGVSVAWG-LWEQ
MAV_3109|M.avium_104                MAGIVGTPGQANYAA-----ANSFLDGLVAHRRADGLAGLSLAWG-LWEQ
MUL_2266|M.ulcerans_Agy99           MAGVVGSSGQANYAA-----ANTFVDGLAAHRRAHGLPAISLGWG-LWDQ
MLBr_00135|M.leprae_Br4923          IAATVGSPGQGNYSA-----ANAFLDGLAAYRQAAGLAGTSLAWG-LWEQ
TH_4621|M.thermoresistible__bu      VGHDQPDPGALSDTG-------------------LDERGGQFPGVGVQIP
                                    :          . :.                       .  .    :   

MAB_0939|M.abscessus_ATCC_1997      VVDKAIPWQANGRPRRAGVSSFGFTGTNAHVLIEEAPQPQATP-------
Mvan_0269|M.vanbaalenii_PYR-1       VVDKAIPWQADGRPRRAGVSSFGFTGTNAHVLIEEAPLPQAAD-------
Mflv_0405|M.gilvum_PYR-GCK          VVDTAMPWQPNGRPRRAGVSSFGFTGTNAHVLIEEAPTDLAGPTEPTAPA
MSMEG_0408|M.smegmatis_MC2_155      VIDEPVPWQTNGRVRRAGVSSFGFTGTNAHVLVEEAPPQLHTADAAP---
Mb1689|M.bovis_AF2122/97            ASAMTRHLGERDRARMTQAGLAPLTTEQALGFLDTA--------------
Rv1661|M.tuberculosis_H37Rv         ASAMTRHLGERDRARMTQAGLAPLTTEQALGFLDTA--------------
MMAR_2471|M.marinum_M               ASAMTRHLGERDKARMSRVGLATLSTEHALELFDAA--------------
MAV_3109|M.avium_104                ASAMTAHLGDRDKARMSRIGLAPLSTEQALAAFDAA--------------
MUL_2266|M.ulcerans_Agy99           ASDMTGGMDAADRARLGREGVLALSSDEAMELFDTA--------------
MLBr_00135|M.leprae_Br4923          PGGMNAHLSSRDLARISRSGLAPMNPAQALELFDAA--------------
TH_4621|M.thermoresistible__bu      VADPGVGIDHRGAVR-----------------------------------
                                               .  *                                   

MAB_0939|M.abscessus_ATCC_1997      ---DEDDASTPQSAPVSVLPLSARSPEALAAVAQRYESWLAAHPDVDLED
Mvan_0269|M.vanbaalenii_PYR-1       ---PVEEPDT-RALPVGVLALSARSPEALTALAQRYEAWLSAHPDADLAD
Mflv_0405|M.gilvum_PYR-GCK          EPVDEDAAADPAPAPVEVLPLSARSPEALVALAQRYETWLTAHPEADLAD
MSMEG_0408|M.smegmatis_MC2_155      -VEPAATAEAGTDDSPQVLALSARSPEALVELARRYDDWLSATPGLDIAD
Mb1689|M.bovis_AF2122/97            ------LQADRAVVVAARLDRAALAGAGAA--LPALFSQLAAGPTRRRI-
Rv1661|M.tuberculosis_H37Rv         ------LQADRAVVVAARLDRAALAGAGAA--LPALFSQLAAGPTRRRI-
MMAR_2471|M.marinum_M               ------VVADRAVVVATRLDANALKSNSAA--LPPLLGELAARPKRRVIS
MAV_3109|M.avium_104                ------MLVETPVLVAARLDRAALSENIAA--LPPLLRELAAGPTRRVI-
MUL_2266|M.ulcerans_Agy99           ------LIVNQAFLAPARIDLAALRAHAVA--VPPMFSDLVSAPTRRQID
MLBr_00135|M.leprae_Br4923          ------LVIDHPFMVTALLDRAALDAQAQAGALPPLFSRLVRRSRRRQIE
TH_4621|M.thermoresistible__bu      --------VDSGVPAQQGVDGEVVRHRTLSSVRSGRSSRWTAPGSRCGSG
                                                      :   .                           

MAB_0939|M.abscessus_ATCC_1997      VCLTAGRGRSHFEHRAALVVDSIQTAREGLLELAQNRLRPGVVRGEHTNH
Mvan_0269|M.vanbaalenii_PYR-1       VCRTAGTGRSHFEHRAALVVDSVAAAREGLAELAQNRLRPGVVRGEHTHH
Mflv_0405|M.gilvum_PYR-GCK          VCRTAGTGRSHFEHRAALVVDSVESARIALTDLAQNRLRPGVVRGEHLNH
MSMEG_0408|M.smegmatis_MC2_155      VCHTAGVGRSHFEYRAALVVDSVERAREGLAALAEGRTPAGVVRGEHVHR
Mb1689|M.bovis_AF2122/97            --DAADTAVSMSGLVSRLHALTPERRQRELTDLVISNAAAVLGR------
Rv1661|M.tuberculosis_H37Rv         --DAADTAVSMSGLVSRLHALTPERRQRELTDLVISNAAAVLGR------
MMAR_2471|M.marinum_M               DADAGDNIAAATGLVARLHGLSAEQRQRELVDVVCSNAATVLGR------
MAV_3109|M.avium_104                --DDADVTASMSGLAARLHGLSPEARRRELVDLVCGNAAMVLGV------
MUL_2266|M.ulcerans_Agy99           --AALATAKSKSALAHRLHGLPELEQHAVVLDLVRSHIATVLGT------
MLBr_00135|M.leprae_Br4923          --DPGDATQSKLALVQRLQGLAANRQLELLVGVVCLQAAAVLGR------
TH_4621|M.thermoresistible__bu      RRYGGESCRRTTGPAAGAAARRGRTRRR----------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      PTTAWLFTGQGSQYPGMARELFDAEPVFAETVTRCAEAVKDIVTRPLLEV
Mvan_0269|M.vanbaalenii_PYR-1       PTTAWLFTGQGSQFPGMARELFETEPVFADAVTRCADAVKDILPRPLLEV
Mflv_0405|M.gilvum_PYR-GCK          PTTAWMFTGQGSQYPGMARELFDTEPVFADTVTRCADAVADLLPRPLLDV
MSMEG_0408|M.smegmatis_MC2_155      PTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAVADMLPRPLLDV
Mb1689|M.bovis_AF2122/97            -------SSSVDINAHKAFQDLGFDSLTAVELRNRLKTATGLTLSPTLIF
Rv1661|M.tuberculosis_H37Rv         -------SSSVDINAHKAFQDLGFDSLTAVELRNRLKTATGLTLSPTLIF
MMAR_2471|M.marinum_M               -------SSTADINAHRAFQELGFDSLTAVELRNRLKTATGLTLSPTLIF
MAV_3109|M.avium_104                -------PDPADINAGRAFQDLGFDSLTAVELRNRLKNATGLTLSPTLIF
MUL_2266|M.ulcerans_Agy99           -------ITPEAIDPDKAFQELGFDSLTAVEMRNRIKTVTGLSLSPTLIF
MLBr_00135|M.leprae_Br4923          -------PSPEDIDPNTKFQDLGFDSLTAVELRNRLKSATGLTLPPTVIF
TH_4621|M.thermoresistible__bu      -------------------RRPRRPPPPPDRVRHRAGPAHGPVRR-----
                                                       .     .  .  : .    . .         

MAB_0939|M.abscessus_ATCC_1997      MFATDRETGGKAGEALRHTSFAQPALFAVEMG------------------
Mvan_0269|M.vanbaalenii_PYR-1       LFAADRESG----EALRHTSFAQPAIFAVEMG------------------
Mflv_0405|M.gilvum_PYR-GCK          MFAGGREAGVPPTETLRHTSFAQPALFAVEMG------------------
MSMEG_0408|M.smegmatis_MC2_155      LFATDRETA----DLLQHTSFAQPALFAVEMG------------------
Mb1689|M.bovis_AF2122/97            DYPTPATLAEHLDSRLVTASGSDQQSLSDRVD------------------
Rv1661|M.tuberculosis_H37Rv         DYPTPATLAEHLDSRLVTASGSDQQSLSDRVD------------------
MMAR_2471|M.marinum_M               DYPSPAALAEHLGIRLATAT--AQPDLMRRFD------------------
MAV_3109|M.avium_104                DYPTPVVLAEHLDSRLAGSGGDDQPDLMGRFN------------------
MUL_2266|M.ulcerans_Agy99           DYPTPNGLANYIRAELAGAPQEVKHTPAVRVTGDDPIAIVGMSCRYPGGI
MLBr_00135|M.leprae_Br4923          DHPTPTAVAEYVAQQMLKSR------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      ----------------LARLWQSWGIEPDVVLGHSVGQYAAACVAG----
Mvan_0269|M.vanbaalenii_PYR-1       ----------------LARLWQSWGIEPDVVLGHSVGQYAAACVAG----
Mflv_0405|M.gilvum_PYR-GCK          ----------------LARLWQSWGIVPDVVLGHSVGQYAAACVAG----
MSMEG_0408|M.smegmatis_MC2_155      ----------------LARLWQSWAIEPDVVLGHSVGQYAAACVAG----
Mb1689|M.bovis_AF2122/97            ----------------------DITRELVVLLD-QPDLS-----------
Rv1661|M.tuberculosis_H37Rv         ----------------------DITRELVVLLD-QPDLS-----------
MMAR_2471|M.marinum_M               ----------------------DLARELDKLIN-RPDWT-----------
MAV_3109|M.avium_104                ----------------------DITRELQALLG-APHWN-----------
MUL_2266|M.ulcerans_Agy99           ESPDDLWDMLMARRDVLSDFPADRGWDLAGLFNPDPDVPGACYTRTGGFV
MLBr_00135|M.leprae_Br4923          ---------------------------PAES-------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      ----------VFSIEDGARLIAERGRLFGGLPAGGRMVAVFSDAKHVEQI
Mvan_0269|M.vanbaalenii_PYR-1       ----------VFSLEDGARLMAERGRMFGSLPEGGRMVAVFTDAKLVEEI
Mflv_0405|M.gilvum_PYR-GCK          ----------VFSLEDGARLMAERGRLFGSLPEGGRMVAVFADAKRVEQV
MSMEG_0408|M.smegmatis_MC2_155      ----------VFSLDDGARLMAERGRMFGSLPEGGRMVAVFADAEHVEQV
Mb1689|M.bovis_AF2122/97            -------------ANVKAHLRTRLQTMLTSLTT--------EDDDIAAAT
Rv1661|M.tuberculosis_H37Rv         -------------ANVKAHLRTRLQTMLTSLTT--------EDDDIAAAT
MMAR_2471|M.marinum_M               -------------HEDKGKLSGRLHDILADLS---------ADDDITTAS
MAV_3109|M.avium_104                -------------SDDKAVLRARIHGLLGALPAGDGPDSAPLDEDLEAAT
MUL_2266|M.ulcerans_Agy99           DRVGDFEPAFFGVGPSEALAMDPQQRMFLELSWEALERAGIEPGGLRGSA
MLBr_00135|M.leprae_Br4923          ------------------------------------------GDETSQAV
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      AGEFPRVSVGAYNG------------------------------------
Mvan_0269|M.vanbaalenii_PYR-1       AGDFPRVSVGAYNG------------------------------------
Mflv_0405|M.gilvum_PYR-GCK          AADFPRVSVGAYNG------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      AGEFPRVSVGAYNG------------------------------------
Mb1689|M.bovis_AF2122/97            ESQLFAILDEELGS------------------------------------
Rv1661|M.tuberculosis_H37Rv         ESQLFAILDEELGS------------------------------------
MMAR_2471|M.marinum_M               ESQLFAILDEELGS------------------------------------
MAV_3109|M.avium_104                ESQLFAILDEELGR------------------------------------
MUL_2266|M.ulcerans_Agy99           TGVFAGVMTQGYGMFAAEPVEGFRLTGQLSSVASGRVAYVLGLEGPAVSV
MLBr_00135|M.leprae_Br4923          EPKVEEVSVHA---------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
Mvan_0269|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           DTACSSSLVALHMAVQSLRSGECDLALAGGVTINATPDIFVEFSRWRGLS
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
Mvan_0269|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           ADGRCKAFAGAADGTGFSEGGGMLVVERLSDAQRLGHPVLALVRGSAVNQ
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
Mvan_0269|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           DGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTTLGDPIE
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
Mvan_0269|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           AQALLATYGQDRGSAGAAGKALWLGSIKSNMGHTQAAAGVAGVIKMVQAM
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
Mvan_0269|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           RHEVLPATLHVDVPSPHVDWSAGAVELLTEAQPWPAESAGDRVRRAGVSS
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
Mvan_0269|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           FGISGTNAHVIVEAAPRVEVGGSSGGAVPVVPWVVSAKSGSALGAQAARL
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
Mvan_0269|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           AAHVRSHDELDVADVGWSLAGRSTFEHRAVVLGADRDGLLAGLDELAGDE
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
Mvan_0269|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           FGGASVIRGVAGAAGKTVFVFPGQGSQLLGMGMGLHAGYPVFAEAFNTVV
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
Mvan_0269|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           GELDRHLLRPLREVIWGHDENLLNTTEFAQPALFAVEVALYRLLESWGVR
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
Mvan_0269|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           PDFVMGHSVGELSAAHVAGVLSLENAAVLVAARGRLMQALPDGGAMIAVQ
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      ----------------------PNTVLSGPGEDLEQAVARFQEEGIRCTW
Mvan_0269|M.vanbaalenii_PYR-1       ----------------------PNTVLSGPGEDLEQIVDRFGDDGVRCTW
Mflv_0405|M.gilvum_PYR-GCK          ----------------------PNTVLSGPGEDLEQIVGTFGEDGIRCTW
MSMEG_0408|M.smegmatis_MC2_155      ----------------------PNTVLSGPGEDLEEIVERFEDEGIRCTW
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           ATEQEVLPLLGAQVSIATINGPASVVISGAQDAVSAVAEQLRADGRRVHR
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      LETSHAFHSELLDPILDEFESYAAQVQFAAPTLPLVCNRTGAVLTAQTPI
Mvan_0269|M.vanbaalenii_PYR-1       LQTSHAFHSELLDPVLDEFESYAAQFQFATPTLPLVCNRTGTVLTAQTPL
Mflv_0405|M.gilvum_PYR-GCK          LETSHAFHSELLDPVLDEFESYAAQLQFAAPTLPLVCNRTGAVLTGQTSL
MSMEG_0408|M.smegmatis_MC2_155      LATSHAFHSELLDPVLDEFEAYAAQFQFAAPTLPLVCNRTGAVLTGQTPL
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           LAVSHAFHSPLMDPMIDEFATVAGELTVNAPTIGIISNLT-GQLAGEDFG
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      DGQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEH
Mvan_0269|M.vanbaalenii_PYR-1       DAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGSAVQVWPEH
Mflv_0405|M.gilvum_PYR-GCK          DAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEH
MSMEG_0408|M.smegmatis_MC2_155      DAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEH
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           SAAYWKRHVRDAVRFADSIRFAQSAGAARFLEVGPSIGLTASIEEVLSDA
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      LAPP--RAIVSLRKGVEDRRQIADALASAYVSGHRPNFAALQRHPRRTVE
Mvan_0269|M.vanbaalenii_PYR-1       LAAP--RAIVSLRKGVSDRRQITEALAAAYVGGHRPDFGALYRRPGRAVA
Mflv_0405|M.gilvum_PYR-GCK          LAAP--RAIASLRKGVADRRQIADALAAAYIGGHKPDFAALHEQRGVRLE
MSMEG_0408|M.smegmatis_MC2_155      MAAP--RAVASLRKGVADRRQIADALASAYVGGHRPDFAAVHRQPRRPVE
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           AVTNPVATASALRKDRPEPVSLVSALAGVFVAGTAVDWRAVVGQS-HFVE
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      LPTYPFQRRRFWPKSSGTAIEGGGGLPSG-----ILGRGEDLASGDSVYI
Mvan_0269|M.vanbaalenii_PYR-1       LPTYPFQRRRFWPKTSGITTDG--PAVSG-----ILGSAKDLASGDTVYT
Mflv_0405|M.gilvum_PYR-GCK          LPTYPFQRRRFWPKSAGMAIDGRVGASAGSG---ILGSGKDLASGDSVYT
MSMEG_0408|M.smegmatis_MC2_155      LPTYPFQRRRFWPKASSIAVDGG-TAASG-----ILGSGKDLASGDTIYT
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           LPTYAFERRRFWLSGDAVPADAAGLGLQAGEHALLGAVVELPASGGVVLT
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      SRLSVRSQPWLSDHVIYGTVVVPGATYAAMALAAVGTPARAKDVFFYEPI
Mvan_0269|M.vanbaalenii_PYR-1       SRWSVRSQPWLADHVIYGTVVVPGATYAAMALAAVGTPARVKDVFFYEPI
Mflv_0405|M.gilvum_PYR-GCK          SRLSVKTQPWLSDHVIYGTVVVPGATYAAMALAAVGTPAHAKDVFFYEPI
MSMEG_0408|M.smegmatis_MC2_155      SRLSVKSQPWLADHVIYGTVVVPGATYAAMALAAVGTPARLKDVFFYEPI
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           GRLSLAAQGWLADHAVGGVVIFPGAGFVELAIRAGDEVGCRVVDELTLAA
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      ILPEKSSREVQLTLHPLEDGSGSKFQVHSRPYGERDVDWSLNAEGTVVTG
Mvan_0269|M.vanbaalenii_PYR-1       ILPEKASREVQLTLHPSEDG-GQKFQVHSREYGERGTEWSLNAEGTVASG
Mflv_0405|M.gilvum_PYR-GCK          ILPEKSSREVQLTVHPSVDG-ESKFQVHSRPYGERGAEWALNAEGVVASG
MSMEG_0408|M.smegmatis_MC2_155      ILPEKASREVQLTLHPADGGSVLSFQIHSRPYGERGADWSLNAEGTVDTA
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           PLVLPSGGSVAVQVVVGSPDDSGARAVSVYSRGDAGSDWVLHAEGSLGSG
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      IGDDAEPAPEAAEPAEPVDAAIERMERMRPMELFEIFADLELAWGPTWSG
Mvan_0269|M.vanbaalenii_PYR-1       VDENPQ-----AEPSGPVDEAIERLNRMRPQDLFETFADMELAWGPTWSG
Mflv_0405|M.gilvum_PYR-GCK          VGDSPAAAG---DLEDPVDEAIERLNRMRPQELFETFADLELAWGPTWSG
MSMEG_0408|M.smegmatis_MC2_155      GSDPDAAAD---EQSDPVDEVIERLERMRPQDLFETFADLELAWGPTWSG
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           SPEPATDLS---------TWPPVGAVEVENADGYQQLAERGYGYGPAFR-
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      SLKSLWLGEGEAIGDVLVGEELAEQLGTEPMHPVLMDLCTGVAFPAFPAL
Mvan_0269|M.vanbaalenii_PYR-1       SLKSLWLGEGEAIGDILVGEELAEQLGTEPMHPVLMDLCTGVAFPAFPAL
Mflv_0405|M.gilvum_PYR-GCK          SLKSLWLGEGEAIGDILVGAELAEQLGTEPMHPVLMDLCTGVAFPAFPAL
MSMEG_0408|M.smegmatis_MC2_155      SLKSLWLGDGEAVGDILVGAELAEQLGSEPMHPVLMDLCTGVAFPAFPAL
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           GLNAMWRRGDEVFAEVALPADAGVSVSGFGIHPVMLDAALHAVILASDGA
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      LAAEQGVNDLFLPLRYGQVTLKEKMPRRFYCRARWHESPLDSETQVFDLD
Mvan_0269|M.vanbaalenii_PYR-1       LAAEQGVSDLFLPLRYGQVTLRDKMPRRFYCRATWHTSELDSETQVFDLD
Mflv_0405|M.gilvum_PYR-GCK          LAAEQGVNDLYLPLRYGQVSLQEKMPRRFYCRATWHEAPLDSETQVFDLE
MSMEG_0408|M.smegmatis_MC2_155      LAAEQGVNDLFLPLRYGQVTLAEKMPRRFYCRARWHRSALDSETQVFELE
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           DDFGVPEGSVLVPFAWQGVTLHAAG------ASAVRARIAPAGPSAVSIE
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      YLDRDGRHLGGIREFTVKRAPREALLRGLGGDATRLLYTLGWHEVAVPPV
Mvan_0269|M.vanbaalenii_PYR-1       FLDRDGRHLGGIREFTVKRAPREALLRGLGGDATRLLYTLGWHEVPAPAS
Mflv_0405|M.gilvum_PYR-GCK          YLDRDGRHLGGVREFTVKRAPREALLRGLGGDATRLLYTLGWHEVPVPES
MSMEG_0408|M.smegmatis_MC2_155      FVDLGGRALGGIREFTVKRAPREALLRGLGGDATRLLYTLGWHEVPPPPS
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           LSDGLGLPVLSVASMLARPVTDQQLRAAVSGAGPDRLFGVDWTAQPSAEL
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      AGEGEESAASIGTWLIAGFDELAAKVPGCIPLNRETDPELLGEVLVAAKE
Mvan_0269|M.vanbaalenii_PYR-1       G-----DAALNGNWLIAGFDELAAGVPGCIPFDRSTDPEPLGQLLAQAHE
Mflv_0405|M.gilvum_PYR-GCK          G----DGAAPQGTWLIGGFDELAVSVPGCIPADR-TNPESLRQLLTDAHG
MSMEG_0408|M.smegmatis_MC2_155      A------DDAVGTWLIAGFDELAAKVPGCVPIDRNTDLQVLGEVLSQAHA
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           Q-------------------PVPVRIWGTVESEGDDDPGASVVFESVPQA
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      RGVPFSGVVWRAAGPGATES--TTESAARLEGEIAHLLSAVHTVQNSAQN
Mvan_0269|M.vanbaalenii_PYR-1       RGIGFSGVVWRAAAPSADES--STAMAARIETEIADLLSAVHTVQN---G
Mflv_0405|M.gilvum_PYR-GCK          RGLPFSGVVWRAARSDGDES--DAEVAARLEAEIAELLGAVHTVQG---G
MSMEG_0408|M.smegmatis_MC2_155      RGAGFSGVVWRCATPGRKESGSASAESARLEAEITNLLSAVHAAQG---P
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           GEVVAGVYAATAAVLEVLRS----------------------------WL
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      GVKLPGGLWIVTERAVATESGEPVDPVQAALWGFGRTTINEEPALRAKLV
Mvan_0269|M.vanbaalenii_PYR-1       AVKLPGGLWIVTERAVATESGEPVDPVQAALWGFGRTTINEEPALRCRLV
Mflv_0405|M.gilvum_PYR-GCK          EVKLPGGLWIVTERAVATESGEPVDPVQAALWGFGRTAINEEPALRCRLV
MSMEG_0408|M.smegmatis_MC2_155      SVKLPGGLWIVTEHGVACESGEPVDPVQAALWGFGRTTINEEPALHCRLV
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           SRDGAGQLIITTRGAVALPDEDVTDLAGSAVWGLVRSAQTEHPGRIVLVD
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      DGDGSPEAVQALARLLVTP-VDEPEIAVRQGKLLASRLLPWSRTGHLTVP
Mvan_0269|M.vanbaalenii_PYR-1       DVDGSPEAVLALAGLLAAP-VDEPELAVRQGKLLASRLLPWARSGHLTVP
Mflv_0405|M.gilvum_PYR-GCK          DCDGSPQAVQALAALLSTP-VDEPELAVRQGKLLASRLLPWSRSGHLTVP
MSMEG_0408|M.smegmatis_MC2_155      DCDGSSEAVDLLAALLAAPGIQEPEIAVRQGKLLASRLLPWARSGHLTLP
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           TDAQLDEHAVAAVLAAGEPQVLWRNGEVYTARVHGSRAV----AGLLVPP
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      RGSDYVLAPTERGAIDNLRITEKEVPAPD--EGYVQVRVEAAGLNFRDVL
Mvan_0269|M.vanbaalenii_PYR-1       RSADYVLAPTERGAIDNLRLTETDVAPPA--EGYVQVRVEAAGLNFRDVL
Mflv_0405|M.gilvum_PYR-GCK          RGGDYVLAPTERGAIDNLRLTDSEVPPPA--EGYVQVRVEAAGLNFRDVL
MSMEG_0408|M.smegmatis_MC2_155      RGGDFVLAPTERGAIDNLRLTETDVPEPD--EGYVQVRVEAAGLNFRDVL
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           GDGPWRLGMSTAGTFENLRLEPIPDADAALQPGHVRVALSAMAANFRDVM
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      NVLGLYPGDPGPIGGDFAGIVTQLGEGVTGVEVGQRVYGSMQGAFGSRFN
Mvan_0269|M.vanbaalenii_PYR-1       NVLGLYPGDPGPIGGDFAGTVTQLGSGVTGLEVGQRVYGFMQGAFASRFN
Mflv_0405|M.gilvum_PYR-GCK          NVLGLYPGDPGPIGGDFAGTVTQLGEGVTGLDVGQRVYGSMQGAFASRFN
MSMEG_0408|M.smegmatis_MC2_155      NVLGLYPGDPGPIGGDFAGTVTQLGAGVSGLEIGQRVYGSMQGAFASRFN
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           IALGLYPDPDAAMGVEGAGVVVETASPDGRFAVGDRVVGLFPEGTGTIAI
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      VPAQFLAPIPDGISGVEAATIPAAALTVR-LSFDWAQLKPGDKVLIHAAS
Mvan_0269|M.vanbaalenii_PYR-1       VPAQLLAPIPDGIGAVDAATIPAAALTAR-LAFDWAQLKPGDRVLIHAAS
Mflv_0405|M.gilvum_PYR-GCK          VPGQFLAPIPDGVSAVEAATIPAAALTVR-LSFDWAQVKSGDKVLIHAAS
MSMEG_0408|M.smegmatis_MC2_155      VPAQFLAPIPDGIGAVEAATIPAAALTVR-LAFDWAQLKPGDKVLIHAAS
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           TDHRLLVKIPAGWSDTAAATTSVVFATAFYALRDLASVQPGQRILVHAAT
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      GGVGLAAIQMAQQFGAEVFATASTFKRATLRKLG--VKYVYDSRTTDFAD
Mvan_0269|M.vanbaalenii_PYR-1       GGVGLAAIQMAQQHGAVVFATASTYKRATLRKLG--VDHVYDSRTTEFAD
Mflv_0405|M.gilvum_PYR-GCK          GGVGLAAVQMAQQCGAEVYATASTFKRATLRKLG--VKHVYDSRTTDFAE
MSMEG_0408|M.smegmatis_MC2_155      GGVGLAAIQMAQQSGAEVFATASTFKRSTLRRLG--VKYVYDSRTTDFAD
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           GGVGMAAVQLARHWGLEVFATASKGKWDTLRAMGFDEDHIGDSRSLEFED
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      QILADTDGAGVDVVLNSLTSEGFIEATLRATAKNGRFAEIAKRDIWTTEQ
Mvan_0269|M.vanbaalenii_PYR-1       QILADTDGEGVDVVLNSLTNEGFIEATVRATAQNGRFAEIAKRDIWTPEQ
Mflv_0405|M.gilvum_PYR-GCK          QILADTDGAGVDVVLNSLTSEGFIEATLRATAQHGRFAEIAKRDIWTVEQ
MSMEG_0408|M.smegmatis_MC2_155      QILADTNGAGVDVVLNSLTSAGFVEATLKATAQGGRFAEIAKRDIWSHEQ
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           KFRAATGGRGMDVVLDSLAGE-FVDASLRLVAPGGVFLEMGKTDIREAAV
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      MAQSRPDIAYEIVALDTVMFQEPDRIRVLLTEVSEGLAKG------EWTP
Mvan_0269|M.vanbaalenii_PYR-1       MAAARPDIAYEIVALDTVTLLEPERIRGLLGEVSDGLGKADGSSRAEWVP
Mflv_0405|M.gilvum_PYR-GCK          MAAARPDLAYEIVALDTVMFTEPDRIRDLLTEVSAGLRDG------AWTP
MSMEG_0408|M.smegmatis_MC2_155      MAEARPDIAYEIVALDTVMFTEPDRIRDLLTEVSDGMARG------EWTP
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           VAQQHTGVRYRAFDLFEAGPDHIAQILAELAALFSEDVLR---------P
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      LPAEIYPLTEARTAFRRMQQARHIGKIVCQMPNPLAPRPDRTYLITGGLG
Mvan_0269|M.vanbaalenii_PYR-1       LPAEIYPLTEARAAFRRMQQARHVGKIVLQMPKPLQPRADRSYLITGGLG
Mflv_0405|M.gilvum_PYR-GCK          LPAEVYPLTEARAAFRRMQQARHIGKIVVQIPNPLQPQPDRSYLITGGLG
MSMEG_0408|M.smegmatis_MC2_155      LPAEIYPITEARSAFRRMQQARHIGKIVLQVPKPLQPQQDRSYLITGGLG
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           LPVTTFDVRRAPAALRYLSQARHVGKVVLTMPDAWAAG---TVLITGGTG
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      AIG-LHTAAYLAQLGAGDIVLTSRRAPDTDAQRVIGEITERSKTRIHVFT
Mvan_0269|M.vanbaalenii_PYR-1       AIG-LHTAAYLAQLGAGDLVLTSRRAPDADARRAIEEITERYKCRVHTFC
Mflv_0405|M.gilvum_PYR-GCK          AIG-LHTAGYLAQLGAGDIVLTSRRAPDAAAQQAIADIADRTKARLHVFT
MSMEG_0408|M.smegmatis_MC2_155      AIG-LHTAAYLAQLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYA
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           MAGSALARHVVAHHGVRQLVLVSRRGPDAPGAAELAEELSAFGAQVQVVA
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      ADVGAESEVAGLLERIRAELPPLAGVAHLAGVLDDALLGQQSVERFRTTL
Mvan_0269|M.vanbaalenii_PYR-1       ADVGDESQVAELLARIRAELPPLAGVAHLAGVLDDALLSQQSLERFRTTL
Mflv_0405|M.gilvum_PYR-GCK          ADVGVEADVAALLERIRAELPPLAGVAHLAGVLDDALLSQQSVERFRTAL
MSMEG_0408|M.smegmatis_MC2_155      ADVGDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTL
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           CDAADRAALAKLIADIPMQHP-LSAVIHTAGALDDAVVTSLTPERIETVL
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      APKAFGAEYLDRLTKGDDLDFFIVSSSVSSLFGSPGQSNYATANALLDGL
Mvan_0269|M.vanbaalenii_PYR-1       APKAFGACHLDRLTAGDDLDFFIMSSSVSSLFGSPGQANYATANALLDGL
Mflv_0405|M.gilvum_PYR-GCK          APKAFGAVHLDRLTRVDDLDFFLVSSSVSSLFGSPGQSNYATANAFLDGL
MSMEG_0408|M.smegmatis_MC2_155      APKAYGASHLDRLTRDDDLDFFIVSSSVSSLFGSPGQANYATANAMLDGL
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           RAKVDAAWNLHELTRDMDLSAFVMFSSMAGLVGSSGQGNYAAANSFLDGL
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      IAQRRAQGLPATGINFGPWGQGGMASSEAATAN------------ISAQG
Mvan_0269|M.vanbaalenii_PYR-1       TAHRRARGLPATGVNFGPWAQGGMASSEAATAN------------IGAQG
Mflv_0405|M.gilvum_PYR-GCK          VAQRRAQGLPATGVNFGPWARGGMASSEAAAAN------------ISAQG
MSMEG_0408|M.smegmatis_MC2_155      VAKRRAQGLVATGINFGPWGQGGMASSEAATAN------------ITAQG
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           AVHRQAHGLPAISLGWGLWDQASNMTGGLAAVDFKRFARDGIVAMSSDEA
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      LIPLDPSAALAALAEVVANGTGQATILKANWQRAAKVLGSSRPPILDLVL
Mvan_0269|M.vanbaalenii_PYR-1       LVPLEPSAALGALAEVLANGTGQAAVLKANWQRAAKVLGSSRPPILDLVL
Mflv_0405|M.gilvum_PYR-GCK          LIPLEPSAALTAMAEVVANGTAQATVLKANWQRAAKVLGSSRPPILDLVL
MSMEG_0408|M.smegmatis_MC2_155      LIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSARPPILDLVL
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           LGLLDTAMVLGEPFMLPAHIDFAALRVKFDGGTLPPMFVDLINAPTRRQV
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      PSAVGEVTGDSELLKQLMEIPVPQRAGFVTEFLQREVQNFLRLAQPP--A
Mvan_0269|M.vanbaalenii_PYR-1       PRPEGEVAGDSELLRQLQEIPVAQRAGFVTEFLQREVQNFLRLAQPP--A
Mflv_0405|M.gilvum_PYR-GCK          PSAVGEITGDSELLKQLQEIPVPQRAGFVTEFLQKEVQNFLRLAQPP--A
MSMEG_0408|M.smegmatis_MC2_155      PSAAGEATGDSELLKQLMEIPIPQRAGFVTEFLQREVQNFLRLASPP--A
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           DDSLAAAKSKSALLQRLEGLPEDEQHAILLNLVRSHIATVLGNSSPDAID
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      ATSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYL
Mvan_0269|M.vanbaalenii_PYR-1       ATSRFLDLGTDSLMAIELRNRLHSQFGGAFTINATAVFDYPTIGGLAEYL
Mflv_0405|M.gilvum_PYR-GCK          ATSRFLDLGTDSLMAIELRNRLHSQFGGAFTINATAVFDYPTIGGLAEYL
MSMEG_0408|M.smegmatis_MC2_155      ASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYL
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           PDRAFQELGFDSLTAVEMRNRLKSATG--LALSPTLIFDYPNSAALAGYM
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      VGQLPDADAESAEAPPAVESAEAESGAGPAAASDAVSELKE---------
Mvan_0269|M.vanbaalenii_PYR-1       VGQLPDSDAAAGETPATETSPIDHNHPDREADSPG---------------
Mflv_0405|M.gilvum_PYR-GCK          VAQLPD-----AETPQAAPQSESEPGPDVTE-------------------
MSMEG_0408|M.smegmatis_MC2_155      VGQLPD-----AEAPETA--------------------------------
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           HRELVGASPQSDTTAEAPGEAELQRVVASIPVKRLRQAGVLELLLALANE
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      ------------------------------------
Mvan_0269|M.vanbaalenii_PYR-1       ------------------------------------
Mflv_0405|M.gilvum_PYR-GCK          ------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      ------------------------------------
Mb1689|M.bovis_AF2122/97            ------------------------------------
Rv1661|M.tuberculosis_H37Rv         ------------------------------------
MMAR_2471|M.marinum_M               ------------------------------------
MAV_3109|M.avium_104                ------------------------------------
MUL_2266|M.ulcerans_Agy99           TGGNGQAAVTAETSEEDLADMDLDALVNAAFMNDDE
MLBr_00135|M.leprae_Br4923          ------------------------------------
TH_4621|M.thermoresistible__bu      ------------------------------------