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M. avium 104 MAV_3109 (-)

annotation: RifB protein
coordinates: 3184095 - 3190469
length: 2124

SGDTEELVRALRQSLKENERLKRENRRYLVAATEPVAVVGMGCRYPGGVDSPEALWEMVVEGRDVVSEFP
ADRGWDLAGLFDADPDAVGKSYCRCGGFLTGVGDFDAAFFGIAPSEALAMDPQQRLLLEVSWEALERAGI
DPATLRGSATGVFAGIFHGSYGGQGRVPGNLERYGLRGSTLSVASGRVAYALGLEGPAVSVDTACSSSLV
ALHLAAQSLRSGECDLALAGGVTVMATPAMFIEFSRQRALAADGRCKAYAGAADGTGFSEGVGVLVLERL
SDARRLGHSVLAVLRGSAVNQDGASNGLATPNGPSQQRVIRAALANARLGAADVDLVEGHGTGTMLGDPI
EAQALLATYGQDRPVDEPLWLGSIKSNMGHTSAAAGAGGVIKMVQAIRHGVMPKTLHVDEPTPQVDWSAG
AVSLLTEARPWPARDRPRRAGVSSFGISGTNAHVIVEQYEPETVAPQGGDVVVPWVLSARSAEALTNQAA
RLLARVKADPGVRVLDVGWSLVSTRSRFEHRAVIVGADGAQLLRRLADLAGGQPGAGVVTGRAQPVGKTV
FVFPGQGSQWPGMGAQLLDRSTVFAEHMHRCARALAEHVDWSLIDVIRGAPGAPGLDRVDVVQPALWAVM
VSLAELWRSVGVVPDAVIGHSQGEIAAACVAGALSLHDAARVVALRSRLLVRLSGRGGMVSLACGRSRAE
QLIAPWGERLNIATVNGISAVVVSGEVDALTELLDRCAADDIRARRIDVDYASHSVQVEEIRDSLAEALR
GIAPRSSAVAFFSTVTGELMDTAALDGDYWFRSIRQTVQFERAVRGAAEAGYRAFIECSPHPVLTAAIEE
TMPDGGQGCVIPSLGRDDGGPDRFWLSAGQAFVSGVVVDWCAMLDGLGGRRVDLPTYGFVRQHFWLPGGS
TGSSDVAALGLRGAEHGLLGAVLPRPDSGGVVLTGRLSTSAQAWLADHAVGDTVLFPGAGFVELAIRAGD
EVGCGVIDELTLSAPLPLPASGGVRLQLVVGAPDEAGRRPLSVYSAAAHQDSEWMLHAEGVLRTGTVTPA
GDLSIWPPIGATAVDVTGGYARLAQRGYEYGRAFRGLRAMWQRGDEIFAEVALPDDAAAGDDFGVHPVLL
DAALHALGVAGEKDQTVLPFSWQGVALHASGASRARVRIAPAGAGAVSVELADGAGLPVLSVRSVTMRPV
SPGQLSAAMGTAQPSGLLDVIWSPIALGGNDLGDEVTLWEPGEHGGDVVKSVHAAVTETLAVLQSWLDGE
GAGVLAVQTHGAVALAGEDVSDLAGAAVWGLVRSAQAEHPGRLVLIDSDGSLDARAVIPCGEPQVVVRQG
VAHAARLRPARAGATLGLPSGAWRLDAGGEGTLGDLVVSRCPRTELADGQVRVAVAAVGVNFRDVLVALG
MYPGGGRLGAEGAGVVVEVGPAVTGLAVGDPVMGLLGVVGSEAVVDQRLLTAVPPGLSLVAAAGVPVVFL
TALYGLSVLSGLRPGERVLVHTATGGVGMAAVQLARHYGAEVFATASRGKWDTLRAMGFDDDHIGDSRSP
DFEQKFLAATGGAGVDVVLNSLAGEFTDASLRLLAPGGRFIEMGKTDVRDPDVVAQRYRGARYRAFDLME
AGPDRTAAMLAEIVGLLRAGVLTPLPLKTFDVRCASTAYRYVSQARHIGKVVLTVPSGPGEVLSGCGGGL
AQSTVLITGGTGMAGSALARHLVDRYRVGHVVLVSRTGAQAAGAAELVDELQRAGASASVLACDVGDRDA
VATMLAGLPSGYPLRGIVHAAGILDDGLLSSLTPDRVDAVLRAKVDGAWNLHELTKDLDLSAFVVFSSMA
GIVGTPGQANYAAANSFLDGLVAHRRADGLAGLSLAWGLWEQASAMTAHLGDRDKARMSRIGLAPLSTEQ
ALAAFDAAMLVETPVLVAARLDRAALSENIAALPPLLRELAAGPTRRVIDDADVTASMSGLAARLHGLSP
EARRRELVDLVCGNAAMVLGVPDPADINAGRAFQDLGFDSLTAVELRNRLKNATGLTLSPTLIFDYPTPV
VLAEHLDSRLAGSGGDDQPDLMGRFNDITRELQALLGAPHWNSDDKAVLRARIHGLLGALPAGDGPDSAP
LDEDLEAATESQLFAILDEELGR*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. avium 104MAV_3109--100% (2124)RifB protein
M. avium 104MAV_3108-0.064.31% (2146) erythronolide synthase, modules 3 and 4
M. avium 104MAV_2450-0.062.01% (2077) erythronolide synthase, modules 3 and 4

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1689pks70.071.26% (2143) polyketide synthase pks7
M. gilvum PYR-GCKMflv_0405-0.037.15% (2148) beta-ketoacyl synthase
M. tuberculosis H37RvRv1661pks70.071.30% (2143) polyketide synthase pks7
M. leprae Br4923MLBr_00135-0.056.16% (2094) putative polyketide synthase
M. abscessus ATCC 19977MAB_0939-0.037.24% (2143) polyketide synthase
M. marinum MMMAR_2471pks70.070.80% (2137) polyketide synthase Pks7
M. smegmatis MC2 155MSMEG_4727-0.033.50% (2149) mycocerosic acid synthase
M. thermoresistible (build 8)TH_4621-0.037.60% (1202) PUTATIVE mycocerosic acid synthase
M. ulcerans Agy99MUL_2266pks120.061.17% (2073) polyketide synthase, Pks12
M. vanbaalenii PYR-1Mvan_1003-0.037.76% (2156) beta-ketoacyl synthase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0405|M.gilvum_PYR-GCK          -----------------------------MGSAAHQGESAHR-FAIVGYA
MAB_0939|M.abscessus_ATCC_1997      -----------------------------MDSAENPIESTPR-FAIIGYA
Mvan_1003|M.vanbaalenii_PYR-1       ---------------MTDLQKRALQAIEVLRARVRELEGAGDGYAIVGYA
Mb1689|M.bovis_AF2122/97            -------MNSTPEDLVKALRRSLKQNERLKRENRDLLARTTEPVAVVGMG
Rv1661|M.tuberculosis_H37Rv         -------MNSTPEDLVKALRRSLKQNERLKRENRDLLARTTEPVAVVGMG
MMAR_2471|M.marinum_M               -------MDSTPDELITALRKTLKENERLKRENRDHLAQATEPVAVVGMG
MAV_3109|M.avium_104                -------MSGDTEELVRALRQSLKENERLKRENRRYLVAATEPVAVVGMG
MUL_2266|M.ulcerans_Agy99           -------MVDQLQHATEALRKALVQVERLKRTKRALLERSSEPIAIVGMS
MLBr_00135|M.leprae_Br4923          MTASVEGADQKSEKLISYLKKVVVELDETRARLREYEQRATEPVAVVGIG
MSMEG_4727|M.smegmatis_MC2_155      -----------------------------------MTQNCVAPVAIIGMA
TH_4621|M.thermoresistible__bu      --------------------------------VNIVGDTPVNAVAVIGMA
                                                                                *::* .

Mflv_0405|M.gilvum_PYR-GCK          GRFPGARD-AESFWELLADGRDAISEVPEDR-WDVEAFFDPDPSTPGKVV
MAB_0939|M.abscessus_ATCC_1997      ARFPGAAD-AEEFWDVLREGRDAISEVPADR-WDAEEFFDPEPGAPGKVV
Mvan_1003|M.vanbaalenii_PYR-1       LRFPGAAD-ADEFWDVLRGGRDAISEVPQDR-WDADEFFDADPEAAGKMV
Mb1689|M.bovis_AF2122/97            CRYPGGVDSPETLWELVAHGRDAVSEFPADRGWDVAGLFDPDPDAVGKSY
Rv1661|M.tuberculosis_H37Rv         CRYPGGVDSPETLWELVAHGRDAVSEFPADRGWDVAGLFDPDPDAVGKSY
MMAR_2471|M.marinum_M               CRYPGGIETPEGLWEMVAAGRDVVSDFPTDRGWDGASLFDPDPDAVGKSY
MAV_3109|M.avium_104                CRYPGGVDSPEALWEMVVEGRDVVSEFPADRGWDLAGLFDADPDAVGKSY
MUL_2266|M.ulcerans_Agy99           CRFPGGVDSPEGLWQMVAEGRDVMSDFPTDRGWDLADLFDPDPDTPHKSY
MLBr_00135|M.leprae_Br4923          CRFPGGVDSPDRLWDVVSECRDVVSEFPTDRGWDVDGLFDPDPDAEGKTY
MSMEG_4727|M.smegmatis_MC2_155      CRLPGAINSPQQLWEALLRGDDFVTEIPTGR-WDAEEYYDPEPGVPGRSV
TH_4621|M.thermoresistible__bu      CRLPGGIDSPQRLWEALLRGDDMVTEIPVDR-WDADDYFDPEPGVPGRTV
                                     * **. : .: :*: :    * :::.* .* **    :*.:* .  :  

Mflv_0405|M.gilvum_PYR-GCK          TRRAGFVDDVSGFDAPFFGMSTREVRLMDPQHRLLLETAWRAIEHSGTAP
MAB_0939|M.abscessus_ATCC_1997      TRRAGFVEDVTGFDAPFFGMSTREVRLMDPQHRLLLETAWRAVEHSGIAP
Mvan_1003|M.vanbaalenii_PYR-1       TRRAGFVEDVAGFDAPFFGVSAREAMFMDPQHRLLLETAWRAVEHSGTAP
Mb1689|M.bovis_AF2122/97            TRCGGFLTDVAGFDAEFFGIAPSEALAMDPQQRLLLEVSWEALERAGIDP
Rv1661|M.tuberculosis_H37Rv         TRCGGFLTDVAGFDAEFFGIAPSEALAMDPQQRLLLEVSWEALERAGIDP
MMAR_2471|M.marinum_M               TRSGGFLTDVAGFDAEFFGIAPSEVMAMDPQQRLLLEVSWEALERTGIDP
MAV_3109|M.avium_104                CRCGGFLTGVGDFDAAFFGIAPSEALAMDPQQRLLLEVSWEALERAGIDP
MUL_2266|M.ulcerans_Agy99           ASTGGFVDGVADFDPGFFGIAPSEALAMDPQHRMLLELSWEALERSGIDP
MLBr_00135|M.leprae_Br4923          TRWGAFLDDAAGFDAGFFGIAPSEVLAMDPQQRLMLEVSWEALEYAGIDP
MSMEG_4727|M.smegmatis_MC2_155      SKWGAFLDDPAAFDPEFFGITEREAAAIDPQHRLLLETAWEAVEHSGLNP
TH_4621|M.thermoresistible__bu      SRWGAFLDDVAGFDPEFFGISEREAISIDPQQRLLLETSWEAMEHAGLTP
                                       ..*: .   **. ***::  *.  :***:*::** :*.*:* :*  *

Mflv_0405|M.gilvum_PYR-GCK          SELANTNTGVFVGLATHDYLGMASDELSYPEIEAYMAIGTSNAAAAGRIS
MAB_0939|M.abscessus_ATCC_1997      TDLAETNSGVFVGLATHDYLGMASDELTFPEIEAYMAIGTSNAAAAGRIS
Mvan_1003|M.vanbaalenii_PYR-1       SALAGTRTGVFMGLSTHDYLGMLTDNLTHDAIEAYLGTGTSPAAAIGRIS
Mb1689|M.bovis_AF2122/97            ITLRGSQTGVFAGVFHGSYGGQG---RVPGDLERYGLRGSTLSVASGRVA
Rv1661|M.tuberculosis_H37Rv         ITLRGSQTGVFAGVFHGSYGGQG---RVPGDLERYGLRGSTLSVASGRVA
MMAR_2471|M.marinum_M               TTLRGSATGVFVGVFHGSYGGQG---RVPGDLERYGLRGSTLSVASGRVA
MAV_3109|M.avium_104                ATLRGSATGVFAGIFHGSYGGQG---RVPGNLERYGLRGSTLSVASGRVA
MUL_2266|M.ulcerans_Agy99           TGLRGSATGVFAGLIVQGYG------MFAEEIEGYRLTGMTSSVASGRVA
MLBr_00135|M.leprae_Br4923          LSLRGSATGVFTGIFAPSYGS-----RDTGGLQGYGLTGTAVSVASGRVS
MSMEG_4727|M.smegmatis_MC2_155      AGLAGSATGVFMGLTHNDYAHLAA--DAKALEGPYGFTGTSFSLASGRIA
TH_4621|M.thermoresistible__bu      ADVEGSSTGVFVGLSHDDYALLTS--DAGALEEAYGFTGSAFSMASGRIA
                                      :  : :*** *:   .*               *   * : : * **::

Mflv_0405|M.gilvum_PYR-GCK          YRLGLQGPAVAVDTACSSSLVAIHQACQALRLGECDLALAGGANVILTPA
MAB_0939|M.abscessus_ATCC_1997      YRLGLQGPSVAVDTACSSSLVAIHQACQALQLGECDLALAGGANVLLTPA
Mvan_1003|M.vanbaalenii_PYR-1       YRLGLQGPAVAVDTACSSSLVAVHQACQALRLAECDVALAGGVNVLLSPA
Mb1689|M.bovis_AF2122/97            YVLGLQGPAVSVDTACSSSLVALHLAVQSLRLGECDLALVGGVTVMATPA
Rv1661|M.tuberculosis_H37Rv         YVLGLQGPAVSVDTACSSSLVALHLAVQSLRLGECDLALVGGVTVMATPA
MMAR_2471|M.marinum_M               YVLGLEGPAVSVDTACSSSLVALHLAVQSLRSRECDLALVGGVTVMATPA
MAV_3109|M.avium_104                YALGLEGPAVSVDTACSSSLVALHLAAQSLRSGECDLALAGGVTVMATPA
MUL_2266|M.ulcerans_Agy99           YVLGLEGPAVSVDTACSSSLVALHMAVQSLRSGECDLALAGGATVNATPT
MLBr_00135|M.leprae_Br4923          YVLGLEGPAVSVDTACSSSLVAIHWAMSSLRSGECDLALAGGVTVMGLPS
MSMEG_4727|M.smegmatis_MC2_155      YALGVHGPAITVDTACSSSLSAIHMACRSLHDGESDVALAGGVSVLLEPR
TH_4621|M.thermoresistible__bu      YRLGVHGPAVTVDTACSSSLLAVHMACRSLQVGESDLALAGGAMVMLEPR
                                    * **:.**:::********* *:* *  :*:  *.*:**.**. *   * 

Mflv_0405|M.gilvum_PYR-GCK          TMITFSNAHMLAPDGRCKTFDAAADGYVRGEGCGVIVIKRLEDAVRDGDR
MAB_0939|M.abscessus_ATCC_1997      TMITFSHAHMLAPDGKCKTFDAAADGYVRGEGSGVIVIKRLEDAIRDGDR
Mvan_1003|M.vanbaalenii_PYR-1       TMINFSRARMLAPDGRCKTFDATADGYVRGEGCGVVVVKRLADAIRHGDR
Mb1689|M.bovis_AF2122/97            MFIEFSRQRALSADGRCKAYAGAADGTAFAEGAGVLVLARLADARRLGHP
Rv1661|M.tuberculosis_H37Rv         MFIEFSRQRALSADGRCKAYAGAADGTAFAEGAGVLVLARLADARRLGHP
MMAR_2471|M.marinum_M               MFIEFSRQRALSADGRCKAYAGAADGTAFSEGAGALVLERLTDAQRLGHP
MAV_3109|M.avium_104                MFIEFSRQRALAADGRCKAYAGAADGTGFSEGVGVLVLERLSDARRLGHS
MUL_2266|M.ulcerans_Agy99           VFVEFSRHRGLAPDGRSKAYAGAADGVGWSEGGAMLVVERLSDAQRLGHP
MLBr_00135|M.leprae_Br4923          IFVGFSRQRGLAADGRCKAFARAADGTGWGEGAGVVVLERLSDAQRLGHT
MSMEG_4727|M.smegmatis_MC2_155      KAAGGSAAGMLSPTGHCHAFDTAADGFVSAEGCVVLTLKRLDDAVADGDR
TH_4621|M.thermoresistible__bu      KYTSASGLGMLSPTGRCHAFDVAADGFVRSEGSVMLLLKRLPDALRDNDR
                                         *    *:. *:.:::  :***   .**   : : ** **   .. 

Mflv_0405|M.gilvum_PYR-GCK          IRAVIRGSAINQDGASGGLTVPNGVAQQRVIGDALSRAGLAPGDVDYLEA
MAB_0939|M.abscessus_ATCC_1997      IRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKRAGVAPSEVGYLEA
Mvan_1003|M.vanbaalenii_PYR-1       IRAVIRGSAVNQDGASGGLTVPNGAAQQRVIADALTNAGLTAADVDYLEA
Mb1689|M.bovis_AF2122/97            VLALVRGSAVNQDGASNGLATPNGPAQQRVITAALASARLGVADVDVVEG
Rv1661|M.tuberculosis_H37Rv         VLALVRGSAVNQDGASNGLATPNGPAQQRVITAALASARLGVADVDVVEG
MMAR_2471|M.marinum_M               VLAVVRGSAVNQDGASNGLATPNGPSQQRVIRAALASARLGVADVDVVEG
MAV_3109|M.avium_104                VLAVLRGSAVNQDGASNGLATPNGPSQQRVIRAALANARLGAADVDLVEG
MUL_2266|M.ulcerans_Agy99           VLALVRGSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEG
MLBr_00135|M.leprae_Br4923          VLAVVRGSAVNQDGASNGLTAPNGLAQQRVIQAALTNAGLSSADVDVVEA
MSMEG_4727|M.smegmatis_MC2_155      ILAVIRGTATNQDGRTVNIATPSADAQAKVYRMALKAAGVEPGTVGLVEA
TH_4621|M.thermoresistible__bu      ILAVVRGTAANQDGRTENISTPSIQAQADVYRSALAVAGVDPATVGMVEA
                                    : *::**:* **** : .::.*.  :*  *   **  * :  . *. :*.

Mflv_0405|M.gilvum_PYR-GCK          HGTGTSLGDPIEAQAAGAALGPG----REPQRPLLIGSAKTNIGHLEAAA
MAB_0939|M.abscessus_ATCC_1997      HGTGTSLGDPIEAQAAGAAYGIG----RETNDPLLIGSAKTNIGHLEAAA
Mvan_1003|M.vanbaalenii_PYR-1       HGTGTPLGDPIEVQAAGAVLGVG----REPDRPLLIGSVKTNIGHLEAAS
Mb1689|M.bovis_AF2122/97            HGTGTTLGDPIEAQAILATYGQ-----RPADRPLWLGSIKSNIGHTSAAA
Rv1661|M.tuberculosis_H37Rv         HGTGTTLGDPIEAQAILATYGQ-----RPADRPLWLGSIKSNIGHTSAAA
MMAR_2471|M.marinum_M               HGTGTTLGDPIEAQAILATYGQDR--TGPGKEPLWLGSIKSNMGHTSAAA
MAV_3109|M.avium_104                HGTGTMLGDPIEAQALLATYGQD----RPVDEPLWLGSIKSNMGHTSAAA
MUL_2266|M.ulcerans_Agy99           HGTGTTLGDPIEAQALLATYGQDRGSAGAAGKALWLGSIKSNMGHTQAAA
MLBr_00135|M.leprae_Br4923          HGTATTLGDPIEAQALLATYGQG----RPADQPLWVGSIKSNMGHTQAAA
MSMEG_4727|M.smegmatis_MC2_155      HGTGTPVGDPLEFSSLAEVYGTDG--------PCALGSIKTNFGHTQSAA
TH_4621|M.thermoresistible__bu      HGTGTPVGDPIEYNSLTQVYGKTG--------PCALTSVKTNFGHAESAA
                                    ***.* :***:* .:   . *           .  : * *:*:** .:*:

Mflv_0405|M.gilvum_PYR-GCK          GIAGVIKVVLSLEHETLPKHLNFENPSPHIPWDRLPVEVVKESIPWRRGQ
MAB_0939|M.abscessus_ATCC_1997      GIAGVIKVILSLENELLPQHRNFQNPSPHIPWDRLPVEVVREARPWGR--
Mvan_1003|M.vanbaalenii_PYR-1       GIAGLLKVILSLEHQVLPKHLNFRSPSPHIPWNRLPVRIVDDPVPWTR--
Mb1689|M.bovis_AF2122/97            GVAGVIKMVQAMRHGVLPKTLHVDVPTPHVDWSAGAVSLLTEPRPWHVP-
Rv1661|M.tuberculosis_H37Rv         GVAGVIKMVQAMRHGVLPKTLHVDVPTPHVDWSAGAVSLLTEPRPWHVP-
MMAR_2471|M.marinum_M               GVAGVIKMTLAMQHGVLPQTLHVDVPTPHVDWSAGSVSLLTEARPWPET-
MAV_3109|M.avium_104                GAGGVIKMVQAIRHGVMPKTLHVDEPTPQVDWSAGAVSLLTEARPWPAR-
MUL_2266|M.ulcerans_Agy99           GVAGVIKMVQAMRHEVLPATLHVDVPSPHVDWSAGAVELLTEAQPWPAES
MLBr_00135|M.leprae_Br4923          GVAGVIKMVQAMRHHVMPATLHVDEPSPRVDWTTGAVSVLTEARDWSVE-
MSMEG_4727|M.smegmatis_MC2_155      GALGVMKAVLALQHNVIPQNLHFTRLPDQMAEIETGLFVPETITPWPVR-
TH_4621|M.thermoresistible__bu      GALGMMKAILALQHGVVPQNLHFTRLPDEMAAIETNLFVPQATTLWPVR-
                                    *  *::*   ::.:  :*   :.   . .:      : :      *    

Mflv_0405|M.gilvum_PYR-GCK          RGGRPRIAGVSSFGFAGTNAHVILEEAPLAAEPAQES---VDDGRFTLLP
MAB_0939|M.abscessus_ATCC_1997      -NGRPRIAGVSSFGFAGTNAHVILEEAPVVSRDAVEPPAPAGGRKFSILP
Mvan_1003|M.vanbaalenii_PYR-1       -SGRSRVAGISSFGFSGTNAHVLVEEAPRADRAGAAPQPAAPGG-FGMLP
Mb1689|M.bovis_AF2122/97            --GRPRRAGVSSFGISGTNAHVILEEAPAVEPVGAAHGNDP--VAVPWV-
Rv1661|M.tuberculosis_H37Rv         --GRPRRAGVSSFGISGTNAHVILEEAPAVEPVGAAHGNDP--VAVPWV-
MMAR_2471|M.marinum_M               --GRARRAGISSFGISGTNAHVILEQAPAAEEVAAQHRTD----LTPWI-
MAV_3109|M.avium_104                --DRPRRAGVSSFGISGTNAHVIVEQY---EPETVAPQGGD--VVVPWV-
MUL_2266|M.ulcerans_Agy99           AGDRVRRAGVSSFGISGTNAHVIVEAAPRVEVGGSS-GGAV--PVVPWV-
MLBr_00135|M.leprae_Br4923          --GRPRRAGVSSFGISGTNAHVILEEAPTPVEASYSTADQQRLSVVPWV-
MSMEG_4727|M.smegmatis_MC2_155      -EGQPRRAAVSAYGLSGTNVHAVLEQAPESPAETAAEAISPKAGNALVFP
TH_4621|M.thermoresistible__bu      -EGCPRRAAVSSYGMSGTNVHAVLEQAP-EPVQRPEESADTDAAGPLVFA
                                      .  * *.:*::*::***.*.::*                       . 

Mflv_0405|M.gilvum_PYR-GCK          LSARTPAALMAVADRYRDWLVANPD-------ATLADLCFTAGTARSHLE
MAB_0939|M.abscessus_ATCC_1997      LSARTPAALAQLADKYRAWLNAHPE-------AALADLCFTAGVGRAHLE
Mvan_1003|M.vanbaalenii_PYR-1       LSARTPDALAATAHRLRTWLAANPD-------ASWPDLCFTAAVGRSHLR
Mb1689|M.bovis_AF2122/97            LSARSAQALTNQARRLLAWVGADEN-------VRPLDVGWSLVNTRSLFD
Rv1661|M.tuberculosis_H37Rv         LSARSAQALTNQARRLLAWVGADEN-------VRPLDVGWSLVNTRSLFD
MMAR_2471|M.marinum_M               LAARSAPALVNQARRLAQWVSDRPD-------LDVADVGWSLATTRSVFE
MAV_3109|M.avium_104                LSARSAEALTNQAARLLARVKADPG-------VRVLDVGWSLVSTRSRFE
MUL_2266|M.ulcerans_Agy99           VSAKSGSALGAQAARLAAHVRSHDE-------LDVADVGWSLAG-RSTFE
MLBr_00135|M.leprae_Br4923          VSGRSTAALMAQASRLAFYVQADPE-------VDPVDVGCALAA-RSVFE
MSMEG_4727|M.smegmatis_MC2_155      VSASSADALRSTAQHLADWLLRSGDGNGRGPAIDLGDLAYTLARRRGFRA
TH_4621|M.thermoresistible__bu      LSSTSAEELRRTAGRLAEWVEAHTD------EVVPADLAYTLARRRAHRP
                                    ::. :   *   * :    :                *:  :    *.   

Mflv_0405|M.gilvum_PYR-GCK          HRAALVVNTREAALDLLGALADDRPA-PGLVRGESHDTPKTAWLFTGQGS
MAB_0939|M.abscessus_ATCC_1997      HRAALVVNTREAAVELLSAVADDRPA-PGLGRGESHDTPKTAWLFTGQGS
Mvan_1003|M.vanbaalenii_PYR-1       HRAALVVDSRSSVEELLGALAEDRPG-PGLARGECGDPPKTAWLFTGQGS
Mb1689|M.bovis_AF2122/97            HRAVVVGADRTQLMEGLTGLAAGVPG-ADVVAGRAQTVGKTAFVFPGQGA
Rv1661|M.tuberculosis_H37Rv         HRAVVVGADRTQLMEGLTGLAAGVPG-ADVVAGRAQTVGKTAFVFPGQGA
MMAR_2471|M.marinum_M               HRAVVVGADRTQLIQGLAGFVDGEPR-AGVVVGRARPVGKTVFVFPGQGS
MAV_3109|M.avium_104                HRAVIVGADGAQLLRRLADLAGGQPG-AGVVTGRAQPVGKTVFVFPGQGS
MUL_2266|M.ulcerans_Agy99           HRAVVLGADRDGLLAGLDELAGDEFGGASVIRGVAGAAGKTVFVFPGQGS
MLBr_00135|M.leprae_Br4923          HRAVVVGESREQLIAGLAGLAVGESG-AGVAIGQAAPLGKTVVVFPGQGA
MSMEG_4727|M.smegmatis_MC2_155      ARSAVLAGDRGTLVEGLRQIADGEAM---PQQAVTNDDRGPVWVFSGQGS
TH_4621|M.thermoresistible__bu      VRTTVIADGVEALTAGLREVADGDAP---YQPAVGMDDKAPVWVFSGQGS
                                     *:.::          *  .. .         .       .. :*.***:

Mflv_0405|M.gilvum_PYR-GCK          QYPGMSRELFDTEPLFAETLRECAAAVDGMLEKPLLDVIFDTDGVLDTDS
MAB_0939|M.abscessus_ATCC_1997      QYPGMARELFETEPVFADTLNRCAAAVADVLEKPLLDVIFDVD---GPEA
Mvan_1003|M.vanbaalenii_PYR-1       QYPGMGRELFDTEPVYREVMTRCAEAVADVLERPLLDVVFDAD------G
Mb1689|M.bovis_AF2122/97            QWLGMGAQLCATAPVFAEHIHRCERALREHVEWSLLDVLRGAP------G
Rv1661|M.tuberculosis_H37Rv         QWLGMGAQLCATAPVFAEHIHRCERALREHVEWSLLDVLRGAP------G
MMAR_2471|M.marinum_M               QWVGMGVDLLDTSTVFADQMHRCEKALAEYVSWSLLDVVRAVP------G
MAV_3109|M.avium_104                QWPGMGAQLLDRSTVFAEHMHRCARALAEHVDWSLIDVIRGAP------G
MUL_2266|M.ulcerans_Agy99           QWIGMGIELLDTAPVFARHIESCGQAFAEFVDWSLLDVLRGAA------G
MLBr_00135|M.leprae_Br4923          QRIGMGRELCSQLPVFAEEFDAVTGELDRHMRLPLRDVVWGAD------A
MSMEG_4727|M.smegmatis_MC2_155      QWASMGAELLDREPAFAAAIAELEPLIAAESDFSVTEALTASET------
TH_4621|M.thermoresistible__bu      QWAGMGAELLATEQVFAAKIAEIEPLVARESGFSVTEAMTASET------
                                    *  .*. :*      :   :      .      .: :.:           

Mflv_0405|M.gilvum_PYR-GCK          NETLRHTSYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVGQYAAACVAG
MAB_0939|M.abscessus_ATCC_1997      EETLRQTSYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVGQYSAACVAE
Mvan_1003|M.vanbaalenii_PYR-1       GEALRHTSYAQPALYAVEMGLARLWQSWGIEPDVVLGHSVGQYAAACVAG
Mb1689|M.bovis_AF2122/97            APGLDRVDVVQPALWAVMVSLAELWRSVGVVPDAVIGHSQGEIAAAYVAG
Rv1661|M.tuberculosis_H37Rv         APGLDRVDVVQPALWAVMVSLAELWRSVGVVPDAVIGHSQGEIAAAYVAG
MMAR_2471|M.marinum_M               APGLNRVDVVQPVLWAIMVSLAELWRSAGVLPDAVIGHSQGEIAAAYVAG
MAV_3109|M.avium_104                APGLDRVDVVQPALWAVMVSLAELWRSVGVVPDAVIGHSQGEIAAACVAG
MUL_2266|M.ulcerans_Agy99           APGLDRIDVVQPVLFAVMVSLAELWKSVGVRPDAVIGHSQGEIAAAYVAG
MLBr_00135|M.leprae_Br4923          G-LLDSTEFAQPALFAVEVALFAVLQHWGLQPDFVMGHSIGELAAAYVAG
MSMEG_4727|M.smegmatis_MC2_155      ---VTGIDRVQPTIFAVQVALAAAMRSHGVVPGAVIGHSMGEVAASVVSG
TH_4621|M.thermoresistible__bu      ---VTGIDRVQPTLFAIQVALAATMQSYGVRPGAVIGHSLGEVAAAVVAG
                                       :   . .**.::*: :.*    :  *. *. *:*** *: :*: *: 

Mflv_0405|M.gilvum_PYR-GCK          VLSLRDGARLMAERGRLFGSLPSGGRMAAVFAAAERV-EALTDEY-PALS
MAB_0939|M.abscessus_ATCC_1997      VFSLEDGARLIAERGRLFSSLPAGGRMAAVFTDAERA-ERLTDEF-PSLS
Mvan_1003|M.vanbaalenii_PYR-1       VMGLEDGAVLLAERGRLFGSLPEGGRMAAVFAPADRV-ESCTVDS-PLLS
Mb1689|M.bovis_AF2122/97            ALSLWDAAAVVALRSRLLVRLGGAGGMVSLACGQPQA-EKLASQWGDRLN
Rv1661|M.tuberculosis_H37Rv         ALSLRDAAAVVALRSRLLVRLGGAGGMVSLACGQPQA-EKLASQWGDRLN
MMAR_2471|M.marinum_M               ALSLEDAARVVARRSQLLVQLSGAGGMVSLACGLERA-RQLVASWSDRLS
MAV_3109|M.avium_104                ALSLHDAARVVALRSRLLVRLSGRGGMVSLACGRSRA-EQLIAPWGERLN
MUL_2266|M.ulcerans_Agy99           ALSLRDAAKVVTLRSKLLVGLAGPGGMVSVACGEQQA-RELLEPFGDRVS
MLBr_00135|M.leprae_Br4923          VLAPADAAMLVVARGRLMQSMPAGGTMWAVAASE----DEVVSLLGEGVG
MSMEG_4727|M.smegmatis_MC2_155      ALSLEDGVKVICRRTRLMTRIAGSGAMAMVELPAQQVLSELASRGVDDVV
TH_4621|M.thermoresistible__bu      ALSLEDGVKVICRRSRLCLRLAGAGAMAAIELPAQAVREFLAARGVDDVV
                                    .:.  *.. ::  * :*   :   * *  :                  : 

Mflv_0405|M.gilvum_PYR-GCK          VAAYNG-ANTVLSGPATDLERAVAGLVADGVRCDWLETSHAFHSALLDPI
MAB_0939|M.abscessus_ATCC_1997      VAAYNG-ANTVLSGPAQDLEKAIAALVADGVRCDFLETSHAFHSALLDPI
Mvan_1003|M.vanbaalenii_PYR-1       VAAYNG-DNTVLSGPAGDLERAVAGFSAAGVRCDWLDTSHAFHSALLDPV
Mb1689|M.bovis_AF2122/97            IAAVNGVSSVVLAGETDAVTELMQRCEAEGIRARRIDVDYASHSAQVDAI
Rv1661|M.tuberculosis_H37Rv         IAAVNGVSSVVLAGETDAVTELMQRCEAEGIRARRIDVDYASHSAQVDAI
MMAR_2471|M.marinum_M               IAAVNGVSAIVVSGEVDALDALIGRCEADDIRARRIDVDYASHSAQVEAI
MAV_3109|M.avium_104                IATVNGISAVVVSGEVDALTELLDRCAADDIRARRIDVDYASHSVQVEEI
MUL_2266|M.ulcerans_Agy99           IAAINGPSAVVVSGEVAALEELIAQCADRELRTRRIDVDYASHSVEVEAI
MLBr_00135|M.leprae_Br4923          IAAINAPESVVISGPQAAVSAIADKFAAQGRRVHQLAVSHAFHSPLMEPM
MSMEG_4727|M.smegmatis_MC2_155      LSVVASPQSTVVGGATASVRELIEMWESRGVMAREIAVDVASHSPQVDPI
TH_4621|M.thermoresistible__bu      LSVIASPESTVIGGATDTVRELVAAWEAQGVMAREVAVDVASHSPQVDPI
                                    ::.  .    *:.*    :                : .. * **  :: :

Mflv_0405|M.gilvum_PYR-GCK          LDDFESYARGITFTAPQRILIDNRTGAALGRSVTLDAAYWRRHARQPVEF
MAB_0939|M.abscessus_ATCC_1997      LDEFEAYANQFNYKTPQRILIDNRTGTALGRSVKLDGAYWRRHARQPVEF
Mvan_1003|M.vanbaalenii_PYR-1       LEEFESCADRFEFGTPQRTLVCNRSGEVLSRHARLDGQYWRRHARQPVRF
Mb1689|M.bovis_AF2122/97            REELIAALRGIEPRTSTVAFFSTVTG-ELMDTAGVNAEYWYRSIRQPVQF
Rv1661|M.tuberculosis_H37Rv         REELIAALRGIEPRTSTVAFFSTVTG-ELMDTAGVNAEYWYRSIRQPVQF
MMAR_2471|M.marinum_M               RAELAEALDGIAPQSTSTAFISTVTG-EFTDTAGLDADYWHRSIRQTVQF
MAV_3109|M.avium_104                RDSLAEALRGIAPRSSAVAFFSTVTG-ELMDTAALDGDYWFRSIRQTVQF
MUL_2266|M.ulcerans_Agy99           EGQLTEVLAGIEPLSSRTAFFSSVTG-SRLDTAELDAEYWYRNIRQTVQF
MLBr_00135|M.leprae_Br4923          LEEFVRVAAQVEVRKPQIGLVSNVTG-ELAGPDFGSPQYWGEHVSRAVRF
MSMEG_4727|M.smegmatis_MC2_155      LDDLIEALADLDPAEPEIPYYS-ATLYDPRDYADYDAYYWADNLRHTVRF
TH_4621|M.thermoresistible__bu      LDELEEILADLQPMTPTVPYYS-ATSYDPREKPVCDADYWVDNLRHEVRF
                                      .:      .    .        :          .  **     : *.*

Mflv_0405|M.gilvum_PYR-GCK          AKSVHTLADMNCKLLVEIGPRPVLTAAALSAWPD----PATSPRVIASLR
MAB_0939|M.abscessus_ATCC_1997      AKSVRTLADMNCKVLLEIGPQPVLTAAALRAWPD----PATAPRAIASLR
Mvan_1003|M.vanbaalenii_PYR-1       AESVRTLADLGCRLLMEIGPQPVLTAAAMRTWPG----TVTAPRVAASMR
Mb1689|M.bovis_AF2122/97            ERAVRNAFDGGYRVFVESSPHPVLIAGIEETLVDCDRGATGEPIVIPTLG
Rv1661|M.tuberculosis_H37Rv         ERAVRNAFDGGYRVFVESSPHPVLIAGIEETLVDCDRGATGEPIVIPTLG
MMAR_2471|M.marinum_M               ERAIRTAFNSGCQVFIESSPHPVLMAGIEETLAGQQD--SGEAIVIPSLG
MAV_3109|M.avium_104                ERAVRGAAEAGYRAFIECSPHPVLTAAIEETMP-----DGGQGCVIPSLG
MUL_2266|M.ulcerans_Agy99           DQAVRSACGHGYRTFIESSPHPALIAGIEDTYRNCAADSGADPIVVPTLG
MLBr_00135|M.leprae_Br4923          VDSARHLQTLGATHFIESGPSSGLMGAIEQSLAP------AEAVVVSMMG
MSMEG_4727|M.smegmatis_MC2_155      SAAVQAALEDGHRVFAELSPHPLLTHPVEQTARS----LDMPLAVFAAMR
TH_4621|M.thermoresistible__bu      AAAVQAALEDGFRVFGELSPHPLLTRAVEQTARG----LDMPVAALPAMR
                                      : :     .   : * .* . *      :             . . : 

Mflv_0405|M.gilvum_PYR-GCK          RTTADQRQITEAVADAYVLGHLPRFAAFRRD-GARVLDLPTYPFEHRQYW
MAB_0939|M.abscessus_ATCC_1997      RNTADHRQITEAAADAYVLGHLPDFGAFQHA-PARKLDLPTYPFERRQYW
Mvan_1003|M.vanbaalenii_PYR-1       RKGSDRRQITEALAQAYVAGHRPETAARQHG-RGRLLDLPTYPFQHRAYW
Mb1689|M.bovis_AF2122/97            RDDGGVGRFWLSAGQAHVAGVGVDWRAAFADLGGRRVELPTYAFARQRFW
Rv1661|M.tuberculosis_H37Rv         RDDGGVGRFWLSAGQAHVAGVGVDWRAAFADLGGRRVELPTYAFARQRFW
MMAR_2471|M.marinum_M               RDDGGLQRFWLSVAQAHVAGVRVDWASIIG--AGRRVALPTYGFQHRRFW
MAV_3109|M.avium_104                RDDGGPDRFWLSAGQAFVSGVVVDWCAMLDGLGGRRVDLPTYGFVRQHFW
MUL_2266|M.ulcerans_Agy99           REDGGLQRFLASAAAAFVAGVNVDWRGPLD--GAGLVELPTYAFEKRRFW
MLBr_00135|M.leprae_Br4923          KDRPELASVLGAAGQLFATGMPVEWPAVFAGSSRRRVTLPTYAFQRRRFW
MSMEG_4727|M.smegmatis_MC2_155      RQQEMPHGLLGFVADLHSAGAAVDFSVLYPT--GRLLDAPLPAWTHSTLL
TH_4621|M.thermoresistible__bu      REQEMPHGVRTMVGDLFAAGAAVDFAALYPS--GRLVDAPLPTWTRRKLV
                                    :       .    .  .  *                :  *   : :    

Mflv_0405|M.gilvum_PYR-GCK          FSDSRE---PVAAAPQR---GARTETVRLLEDGRIEELAALLGGTVDDPF
MAB_0939|M.abscessus_ATCC_1997      FSDKRDGDNRDAGNRQQNNGGPRTEAVRLLEDGKIEELANLLGGVDGDQQ
Mvan_1003|M.vanbaalenii_PYR-1       FPQGQARTAPTDP--------VHTETVRFLDEERIDELAALLDGPTGSAQ
Mb1689|M.bovis_AF2122/97            LDGLGAVGGDLGG------------------VGLVGAEHGLLAAVVQRPD
Rv1661|M.tuberculosis_H37Rv         LDGLGAVGGDLGG------------------VGLVGAEHGLLAAVVQRPD
MMAR_2471|M.marinum_M               LGQLDAGRTDVGG------------------LGQAGAAHGLLGAVVERPD
MAV_3109|M.avium_104                LPGGSTGSSDVAA------------------LGLRGAEHGLLGAVLPRPD
MUL_2266|M.ulcerans_Agy99           LSG-EGVSVDASG------------------LGLSAGGHALLGAVVELPE
MLBr_00135|M.leprae_Br4923          ETPGTDGTASVSG------------------LGLGSTEHALLGAVVERPD
MSMEG_4727|M.smegmatis_MC2_155      LDREL-ESSAPGV--------------------PSVSVHPLLGSHVVLPQ
TH_4621|M.thermoresistible__bu      LSRENGEQQTRGG--------------------CTITVHPLLGTHVRLPE
                                                                            **        

Mflv_0405|M.gilvum_PYR-GCK          TFDVLNRLAAQHNQQRSTESIADDRYQIRWETAAEPPVGADAADGITWLL
MAB_0939|M.abscessus_ATCC_1997      TLNVLTKLAAQHNLQRTTQTIADDRYQFRWEKSPTPLSGSQAAGGVTWLL
Mvan_1003|M.vanbaalenii_PYR-1       TVDVLSKLAARHRQQRGAQSIADARYQIRWEKSEAPGAARPTTEATTWLL
Mb1689|M.bovis_AF2122/97            SGGVVLTG--------------------RISVVAAPWLADHAVGPVVLFP
Rv1661|M.tuberculosis_H37Rv         SGGVVLTG--------------------RISVVAAPWLADHAVGPVVLFP
MMAR_2471|M.marinum_M               SGGVVLTG--------------------QLSVALQPWLAGHAVAGTVLFP
MAV_3109|M.avium_104                SGGVVLTG--------------------RLSTSAQAWLADHAVGDTVLFP
MUL_2266|M.ulcerans_Agy99           SGGVVLTG--------------------RLALGAHGWLADHAVSGVVVFP
MLBr_00135|M.leprae_Br4923          SGGVVLTG--------------------RLSLANQPWLADHVIGGVVLFP
MSMEG_4727|M.smegmatis_MC2_155      EPEEHLWQG-------------------DVGTEAHPWLSDHRVHQVAVLP
TH_4621|M.thermoresistible__bu      EPERHVWQA-------------------DLGTGAQPWLADHQIHTVAALP
                                                                          .       . : 

Mflv_0405|M.gilvum_PYR-GCK          VGDDTDATRPLVDVLAARGHRYRILGLPKSGAEEHELADTLRDAAADATD
MAB_0939|M.abscessus_ATCC_1997      VADAAGAAQPLLDVLTARGQQHRVLALPVSDADEAELVEALRSAADEDSA
Mvan_1003|M.vanbaalenii_PYR-1       VTHDSRAAQPIAEVLERRGHPYHIVGLPGSDADAAPAEEALRATVSQ-PR
Mb1689|M.bovis_AF2122/97            GTGFVELALRAGDEVGCSVLQELTLQAPLVLPADG-VRVQVVVGGVEQSG
Rv1661|M.tuberculosis_H37Rv         GTGFVELALRAGDEVGCSVLQELTLQAPLVLPADG-VRVQVVVGGVEQSG
MMAR_2471|M.marinum_M               GAGFVELAIRAGDEVGCAAVEELTLSAPLVLPTVGGVQLQVVVGPADQSD
MAV_3109|M.avium_104                GAGFVELAIRAGDEVGCGVIDELTLSAPLPLPASGGVRLQLVVGAPDEAG
MUL_2266|M.ulcerans_Agy99           GTGFVELAIRAVDEVGCSVVNELTLRTPLVLPASGSVAVQVVVGAAADSA
MLBr_00135|M.leprae_Br4923          GAGFVELVIRAGDEVGCAGVEELVLAAPLVLHPGSGVQVQVVVAAADESS
MSMEG_4727|M.smegmatis_MC2_155      GAAYCEMALAAVTPVLG-DTGEVHDLKFHDMLLLDDATPVWVSAAVTAPG
TH_4621|M.thermoresistible__bu      GAAYCEMALAAAREVIDSDGVEVRDVRFEQMLLLDEQTEVSAVASAVEPG
                                           .      :                                 . 

Mflv_0405|M.gilvum_PYR-GCK          LRIVHVAALDAAESDTSMKSLLRMQHRVLGGTRRLFGAAVAAQLRSPMWL
MAB_0939|M.abscessus_ATCC_1997      LRIVHVAALAGQGS-SSAQSLLRIQHQVLGGTRRLFRAAAAAELRAPIWI
Mvan_1003|M.vanbaalenii_PYR-1       PHILYLAALEEPGG-SAAETLGWMQHRVLAAARRLFQLAATAGARAPIWL
Mb1689|M.bovis_AF2122/97            TRNVWVYSAAG--------QADSSPGWTLHAQGVLGVGSVQPAAELSVWP
Rv1661|M.tuberculosis_H37Rv         TRNVWVYSAAG--------QADSSPGWTLHAQGVLGVGSVQPAAELSVWP
MMAR_2471|M.marinum_M               HRTVEVYSRGD--------QSLS--EWSLHAEGVLAPAAVASVGQLTAWP
MAV_3109|M.avium_104                RRPLSVYSAAA--------HQDS--EWMLHAEGVLRTGTVTPAGDLSIWP
MUL_2266|M.ulcerans_Agy99           ERSVSIYSRTDTDT-----DTDAGSVWVCHAEGTLGADSAQPAADLSAWP
MLBr_00135|M.leprae_Br4923          RRAVSVYSRGD----------QSHGGWLLNAEGLLEVDAAEATVDLSLWP
MSMEG_4727|M.smegmatis_MC2_155      TAEFGVETHQS-----------GDRTQRATAVLRGDVDAERPAAHSIDAL
TH_4621|M.thermoresistible__bu      TLEFAVETAKD-----------GEHERRATAVLGAADDTEPPQAHDIDAL
                                       . : :                      .       :  .        

Mflv_0405|M.gilvum_PYR-GCK          VTRGAQHVTDTDVVAPDQTCLWGFGRAASLEHPQIWGGLADLGGGT---S
MAB_0939|M.abscessus_ATCC_1997      VTRGAQHVIEGDTVAPEQSALWGFGRAAALELPQVWGGLADLSDAG---T
Mvan_1003|M.vanbaalenii_PYR-1       ITAGAQRITGDETVEPAQTSLWGFGRAAALEQPELWGGLADVTTGD---A
Mb1689|M.bovis_AF2122/97            PV-GARAMDVADGYQVLAARGYGYG--------PAFRGLQALWRRG---A
Rv1661|M.tuberculosis_H37Rv         PV-GARAMDVADGYQVLAARGYGYG--------PAFRGLQALWRRG---A
MMAR_2471|M.marinum_M               PE-GATALDLGGVYDRLAARGYEYG--------PAFRGLQAVWESG---D
MAV_3109|M.avium_104                PI-GATAVDVTGGYARLAQRGYEYG--------RAFRGLRAMWQRG---D
MUL_2266|M.ulcerans_Agy99           PA-GAIAVDVADGYERLDARGYGYG--------PAFRGLTAMWARG---E
MLBr_00135|M.leprae_Br4923          PE-GAESVDISDAYPQLAERGYAYG--------PAFQGLVAIWRRG---S
MSMEG_4727|M.smegmatis_MC2_155      LAAHPNRVDGDELRAGFGTVGIGHG--------AAFAGLSEAYVATAAEP
TH_4621|M.thermoresistible__bu      LAEHPTRIEGDELRQWFDQRGVQFG--------PAFTGLTAARIPEGTVT
                                        .  :               .*          : **           

Mflv_0405|M.gilvum_PYR-GCK          DEWSRLLNRIAATHDPAVMEDQVAVRGSTSYVPRLVHRDT-LPSGKPLHL
MAB_0939|M.abscessus_ATCC_1997      DEWAQFIGRVSVSGEASTREDQLALRGQAVHVPRLVRREE-LPSGKPLEV
Mvan_1003|M.vanbaalenii_PYR-1       EEWSALIDHIVA---APTSEDQIAVRGREIHVARLTRCAE-KANAAALEL
Mb1689|M.bovis_AF2122/97            EVFADVTLPE--GVPIRGFGIHPAVLDAALHAWGIVEG----EQQTMLPF
Rv1661|M.tuberculosis_H37Rv         EVFADVTLPE--GVPIRGFGIHPAVLDAALHAWGIVEG----EQQTMLPF
MMAR_2471|M.marinum_M               EIFAEVALPEDAGAQIGGFGIHPALLDAALHALVLTAE----QNQTVLPF
MAV_3109|M.avium_104                EIFAEVALPDD-AAAGDDFGVHPVLLDAALHALGVAGE----KDQTVLPF
MUL_2266|M.ulcerans_Agy99           ELFAEARLPEA-AGSTSGFGVHPALLDAALHTAVIANP----DADLVLPF
MLBr_00135|M.leprae_Br4923          ELFAEVVAPTG--VVVDGMGMHPALLDAVLHALGLAIENTQATTEMRLPF
MSMEG_4727|M.smegmatis_MC2_155      TVVAAVALPGPLRSGQRGYTVHPALLDACFQSVIAHPEVQNIASGMLLPL
TH_4621|M.thermoresistible__bu      SVLAEVGLPGQIRSQQAPYGIHPALLDACFQSVAAHPDVQGAGSGLLLPL
                                       :                 : .: .                    * .

Mflv_0405|M.gilvum_PYR-GCK          RADATYLVTGGLGSLGLEIAGYLAANGAGHLVLTSRRTPDEAAASRIEAL
MAB_0939|M.abscessus_ATCC_1997      RSDATYLVTGGLGSIGLEIAGYLAGRGAKHLVLTSRREPGEAARQRIDAL
Mvan_1003|M.vanbaalenii_PYR-1       RREATYLVTGGLGALGLEVAEFLASHGAGHLVLTGRRSASDTVRQRIDAM
Mb1689|M.bovis_AF2122/97            SWQGVCLHASGAARVRVRLAP----VGRGAVPVELADPQGLPVLSVRQLM
Rv1661|M.tuberculosis_H37Rv         SWQGVCLHASGAARVRVRLAP----VGRGAVSVELADPQGLPVLSVRQLM
MMAR_2471|M.marinum_M               AWQGVSLHAAGASRCRVRIAQ----SRSGSVAMELADSAGLPVLTVRDLA
MAV_3109|M.avium_104                SWQGVALHASGASRARVRIAP----AGAGAVSVELADGAGLPVLSVRSVT
MUL_2266|M.ulcerans_Agy99           SWQGVSLHAAGAASVRVRIAP----VGPSSVSVELADDLGLPVLSVKAMV
MLBr_00135|M.leprae_Br4923          CWRGVSLHAGGAGRVRARFTS----AGADAIAVDIADSAGLPVLTVRSLV
MSMEG_4727|M.smegmatis_MC2_155      GVRRLRAYGSTRNVRYCLSRIVKADSFGVEADLELLDADGTVLLSAMGLQ
TH_4621|M.thermoresistible__bu      GVRRLQAFGPTRGARYCYARVTDADGSKAEADLDVLDEHGNVLLRVQGLL
                                                                    :      .          

Mflv_0405|M.gilvum_PYR-GCK          RERHGCEV------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      AA-QGCEV------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       RERFDCQV------------------------------------------
Mb1689|M.bovis_AF2122/97            VRPVSAAA------------------------------------------
Rv1661|M.tuberculosis_H37Rv         VRPVSAAA------------------------------------------
MMAR_2471|M.marinum_M               FRPVSDQT------------------------------------------
MAV_3109|M.avium_104                MRPVSPGQ------------------------------------------
MUL_2266|M.ulcerans_Agy99           ARPVSEQQ------------------------------------------
MLBr_00135|M.leprae_Br4923          TRAMTAEQ------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      LGTGNSDKAEEERLLDERLLTIEWQQRELPRPEGSETVDAGSWLVILAGD
TH_4621|M.thermoresistible__bu      MGGAAADGDDRDRVLGERLLTIEWQRRDLPEADS----AAGKWLLVSTS-
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          -----RVVTADVADAHAVARLLATVQAEMPPLAGIVHAAG----------
MAB_0939|M.abscessus_ATCC_1997      -----RAVTADVADGHDVARLLAGIQAELPPLAGIVHAAG----------
Mvan_1003|M.vanbaalenii_PYR-1       -----LVATADVADRDDVARLFSTMRSELPPLAGIVHAAG----------
Mb1689|M.bovis_AF2122/97            -----LSR--STAGD---RGLLEMIWTPVPLEGGDIGDD-----------
Rv1661|M.tuberculosis_H37Rv         -----LSR--STAGD---RGLLEMIWTPVPLEGGDIGDD-----------
MMAR_2471|M.marinum_M               -----SSA--GTAGG---GGLLEVVWSPLARPGDDTADIP----------
MAV_3109|M.avium_104                -----LSAAMGTAQP---SGLLDVIWSPIALGGNDLGDE-----------
MUL_2266|M.ulcerans_Agy99           -----MRAVVSASGP---DRLFEVVWTPMTVAATDAAPAY----------
MLBr_00135|M.leprae_Br4923          -----LRTAVTAAGGALEQGPMDLVWSPIPLSSDGHGGGLPSVVSWADYC
MSMEG_4727|M.smegmatis_MC2_155      DDENPRAAGVVSALIGAGMPTTTMAWSHDADHDAQAAALTAR------LD
TH_4621|M.thermoresistible__bu      ATADVSATRLSDALKQAGAESTSMCWPQQADHADNVDRFRAG------IA
                                                :             .  .                    

Mflv_0405|M.gilvum_PYR-GCK          --------EIGTTPLADLDDAEVDRVFAGKVWGAWHLSEATSDLQLDFFI
MAB_0939|M.abscessus_ATCC_1997      --------EIGTTPLSDLEDAEVDRVFAGKVWGAWHLSEAAAGLKLDFFI
Mvan_1003|M.vanbaalenii_PYR-1       --------EIGTSPLRTLDDAEMDRVFAGKVWGAVYLCEEVADMGLDFFL
Mb1689|M.bovis_AF2122/97            --------AVVWELPPHAG-AQAGGDVLAAVYRGVHEVLEVLQSWLASDA
Rv1661|M.tuberculosis_H37Rv         --------AVVWELPPHAG-AQAGGDVLAAVYRGVHEVLEVLQSWLASDA
MMAR_2471|M.marinum_M               --------VTLWDLASQVE-LSAG--AVESTYVATHGALGALQSWLASDQ
MAV_3109|M.avium_104                --------VTLWEPG------EHGGDVVKSVHAAVTETLAVLQSWLDGEG
MUL_2266|M.ulcerans_Agy99           --------ELFESIA-------ADGDPLSGTYQRTHQALAAVQSWLTEHD
MLBr_00135|M.leprae_Br4923          AGRGNDTGVVVWEFGSASAGAQAPVDSVAAVYSATHAALQVLQFWFGQDR
MSMEG_4727|M.smegmatis_MC2_155      EQPLAGVAVIVGDSETGTDAHDVGADARRGADHVRHLVRIARTLADAVGE
TH_4621|M.thermoresistible__bu      DG-VTGVVVLTGPKNGNPDD----AAARRGSDYVRHLVRITRELAEIDGD
                                                                            .         

Mflv_0405|M.gilvum_PYR-GCK          STSSIASVWGGFGQAAYGAANAFLDGLAWRLREQGVAGVSV--NFGPWSA
MAB_0939|M.abscessus_ATCC_1997      NTSSIAAVWGGYGQTAYSAANAFLDGLAWRLREQGIAGTSV--NFGPWSA
Mvan_1003|M.vanbaalenii_PYR-1       ATSSIASVWGSHGQTAYGAANAFLDGLADSLRARGIPGISV--NFGPWAA
Mb1689|M.bovis_AF2122/97            TGLGVVVTRGAVGPVDDDVTDLAGAAVWGLVRSAQAEHPGR--VVLVDTD
Rv1661|M.tuberculosis_H37Rv         TGLGVVVTRGAVGPVDDDVTDLAGAAVWGLVRSAQAEHPGR--VVLVDTD
MMAR_2471|M.marinum_M               PGVLAVVTHGAVGLADEDVTDLAGSAVWGLVRSAQAEHPGR--VVLVDTD
MAV_3109|M.avium_104                AGVLAVQTHGAVALAGEDVSDLAGAAVWGLVRSAQAEHPGR--LVLIDSD
MUL_2266|M.ulcerans_Agy99           SGVLVVATRGAMALAGEDVTDLAGAAVWGLVRSAQTENPGR--LVLVDSD
MLBr_00135|M.leprae_Br4923          AGTLVVLTRGAVGLVGEGISDLAAAAVWGMVRSAQSEHSGK--IVLIDTD
MSMEG_4727|M.smegmatis_MC2_155      PPRLYVVTHRSQHVLDTDEPYLEHSGLRGLIRVVGMEHPRLRATQIDVDD
TH_4621|M.thermoresistible__bu      APRLFVVTRGAQAVLPQDRPNLEQAGLRGLLRVIGAEHPHLRTTQIDIAD
                                         . .  .      . .     .:   :*                  

Mflv_0405|M.gilvum_PYR-GCK          GMADAQSRAR-LEQRGIKTLSPADALAGLSDAVISAAP-----HPVVARV
MAB_0939|M.abscessus_ATCC_1997      GMADAESRAR-LEQRGIKTLSPTDALAGLADVVAASGSN--AVQGVIARI
Mvan_1003|M.vanbaalenii_PYR-1       GMADAKAREQ-LSRRGVKTLAPADALAGMADVIAASTA-----HAVVARI
Mb1689|M.bovis_AF2122/97            GSVAVEDAVGFGARSGEPQLVVRRGRVYAARLAPVAAG---LTLPSASAG
Rv1661|M.tuberculosis_H37Rv         GSVAVEDAVGFGARSGEPQLVVRRGRVYAARLAPVAAG---LTLPSASAG
MMAR_2471|M.marinum_M               GSVELGAVL----NSGEPQLVVRAGVAYQARLKPAESL---LRLPPPGEN
MAV_3109|M.avium_104                GSLDARAVIP----CGEPQVVVRQGVAHAARLRPARAG---ATLG-LPSG
MUL_2266|M.ulcerans_Agy99           AAVDAAAVAT-ALAVGEPQVVLRNGQPYTARVHASRAAD--GILVPPVDG
MLBr_00135|M.leprae_Br4923          SAVDVAVLAD----LGESQLLVRCNTVHAARLSPAPQL----LALPVGES
MSMEG_4727|M.smegmatis_MC2_155      STAHEALVRQLLSGSPEDETAWRDGQWYAARLCPSPLRAAERRTAVADNA
TH_4621|M.thermoresistible__bu      DADLDRVAVQLLGGGAEDETAWRDGQWYTARLSLSPLRPEERKQAVVDCE
                                                                 :                    

Mflv_0405|M.gilvum_PYR-GCK          DWSRFLPLYQQAGRRGFLAELERELPAAPAQQGPAVTASGRTPLVERLTT
MAB_0939|M.abscessus_ATCC_1997      DWARFLPLYQQAGKRGFLAELDREVPSHLA--GVAGAQSGSTQLVERLAN
Mvan_1003|M.vanbaalenii_PYR-1       DWATFLPVYQLQRRRAFLSQLEREVPDVPD--ASAPAPSGTTRFVEELTL
Mb1689|M.bovis_AF2122/97            GWRLVAGGGGTLADVVVAPVAPV--ELATGQVRVAVGAVGVNFRDVLVAL
Rv1661|M.tuberculosis_H37Rv         GWRLVAGGGGTLADVVVAPVAPV--ELATGQVRVAVGAVGVNFRDVLVAL
MMAR_2471|M.marinum_M               -WRLVTGGGGTLDDVKVGGCAPS--GLMTGQLRVAVAAVGVNFRDVLVAL
MAV_3109|M.avium_104                AWRLDAGGEGTLGDLVVSRCPRT--ELADGQVRVAVAAVGVNFRDVLVAL
MUL_2266|M.ulcerans_Agy99           PWRLGLSSAGTFENLQLEPVPNAGAPLGPGQVRVAMRAIAANFRDIMITL
MLBr_00135|M.leprae_Br4923          MWRLAADGGGTLEDLVIQPCPEVQAPLQAGHMRVAVAAVGVNFRDVVAAL
MSMEG_4727|M.smegmatis_MC2_155      SEGMRLVVRNPGDLESMELVTFERGTPGPGQIEVAVKASSINFADVLVAF
TH_4621|M.thermoresistible__bu      RDGMRLEIRTPGDLETMELAAFDRVPPGPGQIEVAVTASSINFADVLIAF
                                                    .                 *    . .      : 

Mflv_0405|M.gilvum_PYR-GCK          APLQ---QRKRLLTDYLRDAVAEVTRVDAAEIREDAGFFDLGM-DSLMAV
MAB_0939|M.abscessus_ATCC_1997      APVQ---QRKKLLTDYLRDAVAEVTRVDVSEIREDAGFFDLGM-DSLMAV
Mvan_1003|M.vanbaalenii_PYR-1       APVE---QRRKLVLEYLRAAVAEVTRVDAAEIRDEAGFFDLGM-DSLMAI
Mb1689|M.bovis_AF2122/97            GMYP---GGGE-LGVDGAGVVVEVGPGVTGLAVGDRVMGLLG--LVGSEA
Rv1661|M.tuberculosis_H37Rv         GMYP---GGGE-LGVDGAGVVVEVGPGVTGLAVGDRVMGLLG--LVGSEA
MMAR_2471|M.marinum_M               GMYP---GGGE-LGVEGAGIVTEVGPGVSGVAVGDAVMGLLG--VVGPEA
MAV_3109|M.avium_104                GMYP---GGGR-LGAEGAGVVVEVGPAVTGLAVGDPVMGLLG--VVGSEA
MUL_2266|M.ulcerans_Agy99           GMFT---HDAL-IGGEGAGVVVEIGPEVTEFAVGDAVYGFFPD-GSGTLV
MLBr_00135|M.leprae_Br4923          GMYP---GQAPPLGAEGAGVVIEIGPEVTGVAVGDAVMGFLG--GAGPLA
MSMEG_4727|M.smegmatis_MC2_155      GRCPSFDGRLPELGSEFGGVVTAVGPGVTTHRVGDRVGGVSANGCWSNFV
TH_4621|M.thermoresistible__bu      GRYPTFDGRRPQLGTDFAGVVTAVGPDVTSHRVGDRVGGLSPNGCWSTFV
                                    .           :       *  :          :               

Mflv_0405|M.gilvum_PYR-GCK          ELRRRIETGVGKEIPVTLVMDHPRLSDAADYLLGDVLGLTEAAT-APKAA
MAB_0939|M.abscessus_ATCC_1997      ELRRRMEQGVGKEIPVTLVMDHPRISDVADYLLGDVLGLAEQAKPAAQLA
Mvan_1003|M.vanbaalenii_PYR-1       ELRRRLEQGLGKELPVTLAMDHPHLSDAAEYVLGDVLGLSEHTVAQPDTP
Mb1689|M.bovis_AF2122/97            VVDARLVTMVPAGWSLVEAAAVPVAFLTAFYGLSVLAEVAAGQKVLVHAG
Rv1661|M.tuberculosis_H37Rv         VVDARLVTMVPAGWSLVEAAAVPVAFLTAFYGLSVLAEVAAGQKVLVHAG
MMAR_2471|M.marinum_M               VVDHRLVTAVPPGWSLQTAASVPVVFLTAFYGLRVLAEVRSGQKLLVHAA
MAV_3109|M.avium_104                VVDQRLLTAVPPGLSLVAAAGVPVVFLTALYGLSVLSGLRPGERVLVHTA
MUL_2266|M.ulcerans_Agy99           AGDVRLLLPKPADWSYAEAAAISAVFTTAYYAFVHLANVQPGQRVLVHAA
MLBr_00135|M.leprae_Br4923          VVHQQLITQMPQGWSLAEAAAVPVVFLTALFGLADLAGIRAGESVLIHAG
MSMEG_4727|M.smegmatis_MC2_155      TCEADLATKLPEGISEHEAAAVGLAYGTVWLGLTELARMSAGDKILIHSA
TH_4621|M.thermoresistible__bu      TCDADLAVPLPDGLTEGQAAAVSTAHATAWYGLHDLARLGAGEKVLIHSA
                                         :        .   .        ..   :  :  :        .  

Mflv_0405|M.gilvum_PYR-GCK          TVVSTAADEPIAIVAVSCRFPGAPNPEAFWDLLS-GGVDAIREVPEDRFD
MAB_0939|M.abscessus_ATCC_1997      SAVTGRTDEPIAIVAVSCRFPGAPDPEAFWDVLS-GGVDAIREVPEDRFD
Mvan_1003|M.vanbaalenii_PYR-1       STVR--TDDPIAIVGMACRFPGADDTDAFWSVLA-EGADLIREIPDDRFD
Mb1689|M.bovis_AF2122/97            TGGVG-----MAAVSLARYWG----AEVFVTASR-AKWDTLRAMGFDDIH
Rv1661|M.tuberculosis_H37Rv         TGGVG-----MAAVSLARYWG----AEVFVTASR-AKWDTLRAMGFDDIH
MMAR_2471|M.marinum_M               TGGVG-----MAAVQLARLWG----LEVFATASP-GKWDTLRAMGFDDDH
MAV_3109|M.avium_104                TGGVG-----MAAVQLARHYG----AEVFATASR-GKWDTLRAMGFDDDH
MUL_2266|M.ulcerans_Agy99           TGGVG-----MAAVQLARHLG----LEVYATASK-GKWDILRAMGFDEDH
MLBr_00135|M.leprae_Br4923          TGGVG-----MAAVQFARHWG----VEIFVTASR-GKWDTLRDMGFDDDH
MSMEG_4727|M.smegmatis_MC2_155      TGGVG-----QAAIAVARAAG----AEIYATAGSEKRRQLLRDWG--IEH
TH_4621|M.thermoresistible__bu      TGGVG-----LAAIAIARSVG----AQIYATAGSPARRDLLRDMG--IEH
                                    :          * : .:         : :         : :*       .

Mflv_0405|M.gilvum_PYR-GCK          IDEFYDPDPDAAGKTYTRYGGFLDHIDEFDPEFFGLSPREAVWIEPQQRL
MAB_0939|M.abscessus_ATCC_1997      IDEFYDPDPEVAGKTYTRFGGFLDGIDGFDPEFFGISPREAVWIEPQQRL
Mvan_1003|M.vanbaalenii_PYR-1       INEFYDPDPEAAGKIYSRYGGFLDGVDGFDPEFFGISPREAVWIDPQQRL
Mb1689|M.bovis_AF2122/97            ISDSRSLEFEEAFLRATEGSGVDVVLNSLAGEFTDASLR----LLPSGGR
Rv1661|M.tuberculosis_H37Rv         ISDSRSLEFEEAFLRATEGSGVDVVLNSLAGEFTDASLR----LLPSGGR
MMAR_2471|M.marinum_M               IANSRTLEFEEKFRAGTGGVGVDAVLNSLAGEFVDASLR----LLVPGGR
MAV_3109|M.avium_104                IGDSRSPDFEQKFLAATGGAGVDVVLNSLAGEFTDASLR----LLAPGGR
MUL_2266|M.ulcerans_Agy99           ISDSRSLEFEEKFREVTGGRSVDVVLDSLAGEFVDASLR----LLGPGGV
MLBr_00135|M.leprae_Br4923          IGDSRTLEFEEKFLAVTDGRGVDVVLDSLAGDFVDASLR----LLVRGGR
MSMEG_4727|M.smegmatis_MC2_155      VYDSRTTAFADQIRTDTDGYGVDIVLNSVTGPAQRAGLE----LLAFGGR
TH_4621|M.thermoresistible__bu      VYDSRSTAFADEIRRDTDGYGVDVVLNSLPGAAQRAGLE----LLSFGGR
                                    : :             :   ..   :: .       . .    :      

Mflv_0405|M.gilvum_PYR-GCK          MLETVWEGLERAG--YAPSALRGSRTGVFVGVAANEYAHLLSAESIDKIE
MAB_0939|M.abscessus_ATCC_1997      MLETVWEGLERAG--YSPAALRGSRTGIFAGVGANEYAHLLSSESIDKIE
Mvan_1003|M.vanbaalenii_PYR-1       VLETAWEGLERAG--YSAAALRGSRSGVYVGVGANEYSHLLSGGSLDGIE
Mb1689|M.bovis_AF2122/97            FIELGKTDIRDGQ--TVAERHRGVR---YRAFDLVEAGPDRIAAMLSEVV
Rv1661|M.tuberculosis_H37Rv         FIELGKTDIRDGQ--TVAERHRGVR---YRAFDLVEAGPDRIAAMLSEVV
MMAR_2471|M.marinum_M               FIEMGKTDLRDPQ--TMAEQHRGVG---YRAFDLIEAGPDLIARMLAELS
MAV_3109|M.avium_104                FIEMGKTDVRDPD--VVAQRYRGAR---YRAFDLMEAGPDRTAAMLAEIV
MUL_2266|M.ulcerans_Agy99           FLEMGKTDIRDPG--VIAQEYPGVR---YRAFDLFEPGRPRMHQYMLDLA
MLBr_00135|M.leprae_Br4923          FLEMGKTDIRDAQ--EIAANYPGVQ---YRAFDLSEAGPVRMQEMLCEVR
MSMEG_4727|M.smegmatis_MC2_155      FVEIGKRDIYADTRLGLFPFRRNLSFYAVDLALMTVTHPQKIRDLLATVY
TH_4621|M.thermoresistible__bu      FIEIGKRDIYGDTRLGLFPFRRNLAFHGVDLGLMADSHPHKIRELLETVY
                                    .:*    .:             .                      :  : 

Mflv_0405|M.gilvum_PYR-GCK          PHFITGNALNAISGRVAFALGLEGPAVAVDTACSSSLVAVHQAT----QA
MAB_0939|M.abscessus_ATCC_1997      PYFITGNALNAISGRVAFALGFEGPAVAVDTACSSALVAVHQAV----QA
Mvan_1003|M.vanbaalenii_PYR-1       AQFITGNALNVIAGRVSFTLGLEGPAVAVDTACSSSLVAVHQAC----QG
Mb1689|M.bovis_AF2122/97            GLLAAGVLARLPVKTFDARCAPAAYRFVSQARHIGKVVLTIPDG----PG
Rv1661|M.tuberculosis_H37Rv         GLLAAGVLARLPVKTFDARCAPAAYRFVSQARHIGKVVLTIPDG----PG
MMAR_2471|M.marinum_M               RLLCAETLTPLPIKTFDVRLARQAYRFVSQARHIGKVVLTLPDE----TG
MAV_3109|M.avium_104                GLLRAGVLTPLPLKTFDVRCASTAYRYVSQARHIGKVVLTVPSG----PG
MUL_2266|M.ulcerans_Agy99           GLFDAGVLRPLPVTAFDVRRAPAALRYLSQARHVGKVVMTMPAD----QG
MLBr_00135|M.leprae_Br4923          ELFDTQVLHRLPVTSWDVRCAPAAFRFMSQARHIGKVVLTMPSA----LA
MSMEG_4727|M.smegmatis_MC2_155      RLIADGTLPLPEITHYPLEEAATAIRIMGGAQHTGKLVIDIPDTGQSQVV
TH_4621|M.thermoresistible__bu      RLTADGVLPMPQSTHYPLAEAATAIRVMSAAEHVGKLVLDVPHTGRADVV
                                                        .  .      :   . :*            

Mflv_0405|M.gilvum_PYR-GCK          LRSGDCDMALAGGVNVLLSPVTVVAASRARMLSPVGRCKTFDASADGYVR
MAB_0939|M.abscessus_ATCC_1997      LHSGDCDLALAGGVNVLLSPVTVIAASRARMLSPVGRCKTFDASADGYVR
Mvan_1003|M.vanbaalenii_PYR-1       LQSGDCDLALAGGVNVLLSPATTIATSRARMLSPDGRCKTFDAAADGYVR
Mb1689|M.bovis_AF2122/97            GQSG-----LAGGTVVVTGGTGMAGSAVATHLVRRHGVANLVLVSRSGEQ
Rv1661|M.tuberculosis_H37Rv         GQSG-----LAGGTVVVTGGTGMAGSAVATHLVRRHGVANLVLVSRSGEQ
MMAR_2471|M.marinum_M               AVPAGA---LAGGTVIITGGTGMAGTALARHVVSRHRVANVILVSRSGAQ
MAV_3109|M.avium_104                EVLSGCGGGLAQSTVLITGGTGMAGSALARHLVDRYRVGHVVLVSRTGAQ
MUL_2266|M.ulcerans_Agy99           GALG-------GGTVLITGGTGMAGSALARHLVAHHGVAHLVLISRRGPA
MLBr_00135|M.leprae_Br4923          DGLA-------EGTVLITGASGAIGGVLARHMVSAYGVRHLVLASRRGDR
MSMEG_4727|M.smegmatis_MC2_155      VPPEQVPVFRGDGAYVITGGLGGLGLFLAERMAAAG-CGRIVVNSRSAPS
TH_4621|M.thermoresistible__bu      VPPEQASPFRSDGAYIVTGGMGGLGLYLAGEMAAAG-AGCIVLNGRSAPS
                                                .. :: .     .   *  :        .   .     

Mflv_0405|M.gilvum_PYR-GCK          SEGCGILVLKRLSDAVRDGDRVCAVIAGSAVNQDGASSGLTVPNGGAQQR
MAB_0939|M.abscessus_ATCC_1997      SEGCGILVLKRLSDAERDGDRVLAVIPGSAVNQDGASSGLTVPNGGAQQR
Mvan_1003|M.vanbaalenii_PYR-1       GEGCGILVLKRLSDAVRDGDRIQAVIRGSAVNQDGASGGLTVPNGGAQQR
Mb1689|M.bovis_AF2122/97            ADRA-----AEVAALLREGGAQVAVVSCDVADRD-ALAALLAGLDPRYP-
Rv1661|M.tuberculosis_H37Rv         ADRA-----AEVAALLREGGAQVAVVSCDVADRD-ALAALLAGLDPRYP-
MMAR_2471|M.marinum_M               AEGT-----SELLGQLQDAGAEAAVVACDVSDRD-AVAELLAQVPARYP-
MAV_3109|M.avium_104                AAGA-----AELVDELQRAGASASVLACDVGDRD-AVATMLAGLPSGYP-
MUL_2266|M.ulcerans_Agy99           APGA-----TELVAELSAAGAQVEVVACDAADRP-ALAKVIAENPAQRP-
MLBr_00135|M.leprae_Br4923          AEGA-----VELAAELVGAGAKIQVVACDVADND-AVRGLFAQLSREFPP
MSMEG_4727|M.smegmatis_MC2_155      TRSS------EIIELIRATGADIVVECGDIAEPDTALRLVAAATQTGLP-
TH_4621|M.thermoresistible__bu      GEAL------RTIEQLRAAGTEVIVECGXX----XRGQPVEVAVPT----
                                              .        .    *              : .        

Mflv_0405|M.gilvum_PYR-GCK          LIGTVLARAGITGGEVDYLEAHGTGTPLGDPIEVQAAAAAYAGARDADRP
MAB_0939|M.abscessus_ATCC_1997      LIGSVLARAGLVGGDVDYLEAHGTGTPLGDPIEVQAAAAAYGGSRDADRP
Mvan_1003|M.vanbaalenii_PYR-1       VIAAALTRAGLSGSDIDYLEAHGTGTSLGDPIEVQAAGAVLGAGRDPDRP
Mb1689|M.bovis_AF2122/97            LKGVFHAAGVLDDAVITGLTPDRVDTVLRAKVDGAWNLHELTEDMDLSAF
Rv1661|M.tuberculosis_H37Rv         LKGVFHAAGVLDDAVITGLTPDRVDTVLRAKVDGAWNLHELTEDMDLSAF
MMAR_2471|M.marinum_M               LRGVIHAAGVLDDGLIASLTPQRVDTVLRAKIDGAWNLHELTRGLNLSAF
MAV_3109|M.avium_104                LRGIVHAAGILDDGLLSSLTPDRVDAVLRAKVDGAWNLHELTKDLDLSAF
MUL_2266|M.ulcerans_Agy99           LSAVVHAGGVLDDAVISSLTPERVDTVLRAKVDAAWNLHELTRDLDLSAF
MLBr_00135|M.leprae_Br4923          VRGVIHAAGVLDDGAITSLTPDRVDTVLRAKVDAAWNLHEATRDLDLLMF
MSMEG_4727|M.smegmatis_MC2_155      LRGVLHAAAVVEDATLANITDELVEHDWAPKVYGAWNLHQAVQSGGPATS
TH_4621|M.thermoresistible__bu      ---ELRHADEHPDRRGAQLCDEFARGEQG----AQRNQHRTDAGEGQRD-
                                                .     :  . .                     .    

Mflv_0405|M.gilvum_PYR-GCK          LLMGSVKTNIGHTESASGAAGLIKVVLSLQHETLPQSLHFDTPSPHIPWD
MAB_0939|M.abscessus_ATCC_1997      LLMGSVKSNIGHTESASGAAGLIKVVLSLQNGVLPQSLHFDNPSPHIPWE
Mvan_1003|M.vanbaalenii_PYR-1       LLMGSVKTNVGHLESASGVAGLIKVVLSLQHEMLPRHLHFKTPSPHIPWD
Mb1689|M.bovis_AF2122/97            VVFSSMAGIVGTPAQGN-----YAAANAFLDGLVAYRRSRGLAGLSVAWG
Rv1661|M.tuberculosis_H37Rv         VVFSSMAGIVGTPAQGN-----YAAANAFLDGLVAYRRSRGLAGLSVAWG
MMAR_2471|M.marinum_M               VLFSSMAGIIGTAGQGN-----YAAANSFLDGLAVHRRALGLPGVSVAWG
MAV_3109|M.avium_104                VVFSSMAGIVGTPGQAN-----YAAANSFLDGLVAHRRADGLAGLSLAWG
MUL_2266|M.ulcerans_Agy99           VMFSSMAGVVGSSGQAN-----YAAANTFVDGLAAHRRAHGLPAISLGWG
MLBr_00135|M.leprae_Br4923          VLCSSIAATVGSPGQGN-----YSAANAFLDGLAAYRQAAGLAGTSLAWG
MSMEG_4727|M.smegmatis_MC2_155      ELDWFCAFSSAAALVGSPGQGAYAAANSWLDAFMQWRRAQGLPATSIAWG
TH_4621|M.thermoresistible__bu      ------AHPPGAVGHDQPDPGALSDTG------LDERGGQ----------
                                              .     .        .                        

Mflv_0405|M.gilvum_PYR-GCK          SLPVRVVDTAMPWQPNGRPRRAGVSSFGFTGTNAHVLIEEAPTDLAGPTE
MAB_0939|M.abscessus_ATCC_1997      SLPVRVVDKAIPWQANGRPRRAGVSSFGFTGTNAHVLIEEAPQPQATP--
Mvan_1003|M.vanbaalenii_PYR-1       RLAVRVVAEPTPWRADGRPRRAGVSSFGFSGTNAHVVLEEPPAQSADLRQ
Mb1689|M.bovis_AF2122/97            -LWEQASAMTRHLGERDRARMTQAGLAPLTTEQALGFLDTA---------
Rv1661|M.tuberculosis_H37Rv         -LWEQASAMTRHLGERDRARMTQAGLAPLTTEQALGFLDTA---------
MMAR_2471|M.marinum_M               -LWEQASAMTRHLGERDKARMSRVGLATLSTEHALELFDAA---------
MAV_3109|M.avium_104                -LWEQASAMTAHLGDRDKARMSRIGLAPLSTEQALAAFDAA---------
MUL_2266|M.ulcerans_Agy99           -LWDQASDMTGGMDAADRARLGREGVLALSSDEAMELFDTA---------
MLBr_00135|M.leprae_Br4923          -LWEQPGGMNAHLSSRDLARISRSGLAPMNPAQALELFDAA---------
MSMEG_4727|M.smegmatis_MC2_155      AWGEIGRGTAMAEGDNAIAP------------------------------
TH_4621|M.thermoresistible__bu      ---FPGVGVQIPVADPGVGI------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          PTAPAEPVDEDAAADPAPAPVEVLPLSARSPEALVALAQRYETWLTAHPE
MAB_0939|M.abscessus_ATCC_1997      --------DEDDASTPQSAPVSVLPLSARSPEALAAVAQRYESWLAAHPD
Mvan_1003|M.vanbaalenii_PYR-1       PPTDGKDGAAGLESATAPEPAGVLPISARSPEALTALARRYESWLTAHPD
Mb1689|M.bovis_AF2122/97            -----------LQADRAVVVAARLDRAALAGAGAA--LPALFSQLAAGPT
Rv1661|M.tuberculosis_H37Rv         -----------LQADRAVVVAARLDRAALAGAGAA--LPALFSQLAAGPT
MMAR_2471|M.marinum_M               -----------VVADRAVVVATRLDANALKSNSAA--LPPLLGELAARPK
MAV_3109|M.avium_104                -----------MLVETPVLVAARLDRAALSENIAA--LPPLLRELAAGPT
MUL_2266|M.ulcerans_Agy99           -----------LIVNQAFLAPARIDLAALRAHAVA--VPPMFSDLVSAPT
MLBr_00135|M.leprae_Br4923          -----------LVIDHPFMVTALLDRAALDAQAQAGALPPLFSRLVRRSR
MSMEG_4727|M.smegmatis_MC2_155      --------------DEGAYAFEAILRHDRVYNGYAPVLGASWLTAFAQRS
TH_4621|M.thermoresistible__bu      --------------DHRG--------AVRVDSGVP-----------AQQG
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          ADLADVCRTAGTGRSHFEHRAALVVDSVESARIALTDLAQNRLRPGVVRG
MAB_0939|M.abscessus_ATCC_1997      VDLEDVCLTAGRGRSHFEHRAALVVDSIQTAREGLLELAQNRLRPGVVRG
Mvan_1003|M.vanbaalenii_PYR-1       ADIADVCYTAGAGRSHFEHRAALVVDSVDGARDLLAGLAEDRLGPGAVRG
Mb1689|M.bovis_AF2122/97            RRRI---DAADTAVSMSGLVSRLHALTPERRQRELTDLVISNAAAVLGR-
Rv1661|M.tuberculosis_H37Rv         RRRI---DAADTAVSMSGLVSRLHALTPERRQRELTDLVISNAAAVLGR-
MMAR_2471|M.marinum_M               RRVISDADAGDNIAAATGLVARLHGLSAEQRQRELVDVVCSNAATVLGR-
MAV_3109|M.avium_104                RRVI---DDADVTASMSGLAARLHGLSPEARRRELVDLVCGNAAMVLGV-
MUL_2266|M.ulcerans_Agy99           RRQID--AALATAKSKSALAHRLHGLPELEQHAVVLDLVRSHIATVLGT-
MLBr_00135|M.leprae_Br4923          RRQIE--DPGDATQSKLALVQRLQGLAANRQLELLVGVVCLQAAAVLGR-
MSMEG_4727|M.smegmatis_MC2_155      PFAELFLADTQGASETRKLRSELAALPREEWPTHLRRLIAEQVGLLLRR-
TH_4621|M.thermoresistible__bu      VDGEVVRHRTLSS--VRSGRSSRWTAPGSRCGSGRR-----YGGESCRR-
                                                              .                       

Mflv_0405|M.gilvum_PYR-GCK          EHLNHPTTAWMFTGQGSQYPGMARELFDTEPVFADTVTRCADAVADLLPR
MAB_0939|M.abscessus_ATCC_1997      EHTNHPTTAWLFTGQGSQYPGMARELFDAEPVFAETVTRCAEAVKDIVTR
Mvan_1003|M.vanbaalenii_PYR-1       VCGDPPKTAWLFTGQGSQYPGMARELFDTEPVFRDTVTRCAEAIGDTLPR
Mb1689|M.bovis_AF2122/97            ------------SSSVDINAHKAFQDLGFDSLTAVELRNRLKTATGLTLS
Rv1661|M.tuberculosis_H37Rv         ------------SSSVDINAHKAFQDLGFDSLTAVELRNRLKTATGLTLS
MMAR_2471|M.marinum_M               ------------SSTADINAHRAFQELGFDSLTAVELRNRLKTATGLTLS
MAV_3109|M.avium_104                ------------PDPADINAGRAFQDLGFDSLTAVELRNRLKNATGLTLS
MUL_2266|M.ulcerans_Agy99           ------------ITPEAIDPDKAFQELGFDSLTAVEMRNRIKTVTGLSLS
MLBr_00135|M.leprae_Br4923          ------------PSPEDIDPNTKFQDLGFDSLTAVELRNRLKSATGLTLP
MSMEG_4727|M.smegmatis_MC2_155      ----------------TVDPDRPLSEYGLDSLGHLELRTRIETETGVRVS
TH_4621|M.thermoresistible__bu      ----------------TTGP----------AAGAAARRGRTRRRRRPRRP
                                                       .          .                   

Mflv_0405|M.gilvum_PYR-GCK          PLLDVMFAGGREAGVPPTETLRHTSFAQPALFAVEMG-------------
MAB_0939|M.abscessus_ATCC_1997      PLLEVMFATDRETGGKAGEALRHTSFAQPALFAVEMG-------------
Mvan_1003|M.vanbaalenii_PYR-1       PLLEVLFDTDGDNG----QTLRHTSYAQPALFAIEMG-------------
Mb1689|M.bovis_AF2122/97            PTLIFDYPTPATLAEHLDSRLVTASGSDQQSLSDRVD-------------
Rv1661|M.tuberculosis_H37Rv         PTLIFDYPTPATLAEHLDSRLVTASGSDQQSLSDRVD-------------
MMAR_2471|M.marinum_M               PTLIFDYPSPAALAEHLGIRLATAT--AQPDLMRRFD-------------
MAV_3109|M.avium_104                PTLIFDYPTPVVLAEHLDSRLAGSGGDDQPDLMGRFN-------------
MUL_2266|M.ulcerans_Agy99           PTLIFDYPTPNGLANYIRAELAGAPQEVKHTPAVRVTGDDPIAIVGMSCR
MLBr_00135|M.leprae_Br4923          PTVIFDHPTPTAVAEYVAQQMLKSR-------------------------
MSMEG_4727|M.smegmatis_MC2_155      AMDMTTIRGLAQRLCEMLDTDDAVSAPS----------------------
TH_4621|M.thermoresistible__bu      PPPPDRVRHRAG------PAHGPVRR------------------------
                                    .                                                 

Mflv_0405|M.gilvum_PYR-GCK          ---------------------LARLWQSWGIVPDVVLGHSVGQYAAACVA
MAB_0939|M.abscessus_ATCC_1997      ---------------------LARLWQSWGIEPDVVLGHSVGQYAAACVA
Mvan_1003|M.vanbaalenii_PYR-1       ---------------------LARLWQARGIEPDVVLGHSVGQYAAACVA
Mb1689|M.bovis_AF2122/97            ---------------------------DITRELVVLLD-QPDLS------
Rv1661|M.tuberculosis_H37Rv         ---------------------------DITRELVVLLD-QPDLS------
MMAR_2471|M.marinum_M               ---------------------------DLARELDKLIN-RPDWT------
MAV_3109|M.avium_104                ---------------------------DITRELQALLG-APHWN------
MUL_2266|M.ulcerans_Agy99           YPGGIESPDDLWDMLMARRDVLSDFPADRGWDLAGLFNPDPDVPGACYTR
MLBr_00135|M.leprae_Br4923          --------------------------------PAES--------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          G--------------VFSLEDGARLMAERGRLFGSLPEGGRMVAVFADAK
MAB_0939|M.abscessus_ATCC_1997      G--------------VFSIEDGARLIAERGRLFGGLPAGGRMVAVFSDAK
Mvan_1003|M.vanbaalenii_PYR-1       G--------------VFGLEDGARLVADRGRLFGGLPVGGRMVAVFTDAE
Mb1689|M.bovis_AF2122/97            ------------------ANVKAHLRTRLQTMLTSLTT--------EDDD
Rv1661|M.tuberculosis_H37Rv         ------------------ANVKAHLRTRLQTMLTSLTT--------EDDD
MMAR_2471|M.marinum_M               ------------------HEDKGKLSGRLHDILADLS---------ADDD
MAV_3109|M.avium_104                ------------------SDDKAVLRARIHGLLGALPAGDGPDSAPLDED
MUL_2266|M.ulcerans_Agy99           TGGFVDRVGDFEPAFFGVGPSEALAMDPQQRMFLELSWEALERAGIEPGG
MLBr_00135|M.leprae_Br4923          -----------------------------------------------GDE
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          RVEQVAADFPRVSVGAYNG-------------------------------
MAB_0939|M.abscessus_ATCC_1997      HVEQIAGEFPRVSVGAYNG-------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       VVEDFADEFPQVSVAAYNG-------------------------------
Mb1689|M.bovis_AF2122/97            IAAATESQLFAILDEELGS-------------------------------
Rv1661|M.tuberculosis_H37Rv         IAAATESQLFAILDEELGS-------------------------------
MMAR_2471|M.marinum_M               ITTASESQLFAILDEELGS-------------------------------
MAV_3109|M.avium_104                LEAATESQLFAILDEELGR-------------------------------
MUL_2266|M.ulcerans_Agy99           LRGSATGVFAGVMTQGYGMFAAEPVEGFRLTGQLSSVASGRVAYVLGLEG
MLBr_00135|M.leprae_Br4923          TSQAVEPKVEEVSVHA----------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           PAVSVDTACSSSLVALHMAVQSLRSGECDLALAGGVTINATPDIFVEFSR
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           WRGLSADGRCKAFAGAADGTGFSEGGGMLVVERLSDAQRLGHPVLALVRG
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           SAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTTL
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           GDPIEAQALLATYGQDRGSAGAAGKALWLGSIKSNMGHTQAAAGVAGVIK
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           MVQAMRHEVLPATLHVDVPSPHVDWSAGAVELLTEAQPWPAESAGDRVRR
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           AGVSSFGISGTNAHVIVEAAPRVEVGGSSGGAVPVVPWVVSAKSGSALGA
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           QAARLAAHVRSHDELDVADVGWSLAGRSTFEHRAVVLGADRDGLLAGLDE
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           LAGDEFGGASVIRGVAGAAGKTVFVFPGQGSQLLGMGMGLHAGYPVFAEA
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           FNTVVGELDRHLLRPLREVIWGHDENLLNTTEFAQPALFAVEVALYRLLE
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           SWGVRPDFVMGHSVGELSAAHVAGVLSLENAAVLVAARGRLMQALPDGGA
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          ---------------------------PNTVLSGPGEDLEQIVGTFGEDG
MAB_0939|M.abscessus_ATCC_1997      ---------------------------PNTVLSGPGEDLEQAVARFQEEG
Mvan_1003|M.vanbaalenii_PYR-1       ---------------------------PNTVLAGPASDLEQIVAGCSGEG
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           MIAVQATEQEVLPLLGAQVSIATINGPASVVISGAQDAVSAVAEQLRADG
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          IRCTWLETSHAFHSELLDPVLDEFESYAAQLQFAAPTLPLVCNRTGAVLT
MAB_0939|M.abscessus_ATCC_1997      IRCTWLETSHAFHSELLDPILDEFESYAAQVQFAAPTLPLVCNRTGAVLT
Mvan_1003|M.vanbaalenii_PYR-1       IRTTWLDTSHAFHSALLDPVLDEFESCAARLAYAAPTRPLVCNRTGAVVT
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           RRVHRLAVSHAFHSPLMDPMIDEFATVAGELTVNAPTIGIISNLT-GQLA
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          GQTSLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQ
MAB_0939|M.abscessus_ATCC_1997      AQTPIDGQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQ
Mvan_1003|M.vanbaalenii_PYR-1       GPGVIDAQYWRRHARQPVQFAESVRTLADLGCSVLMEIGPQPFLIAAALR
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           GEDFGSAAYWKRHVRDAVRFADSIRFAQSAGAARFLEVGPSIGLTASIEE
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          VWPEHLAAP--RAIASLRKGVADRRQIADALAAAYIGGHKPDFAALHEQR
MAB_0939|M.abscessus_ATCC_1997      VWPEHLAPP--RAIVSLRKGVEDRRQIADALASAYVSGHRPNFAALQRHP
Mvan_1003|M.vanbaalenii_PYR-1       VWPESAATP--RAIPSLRKGPDARRQLAEAVAAAYIAGHRLDFTGHDGGP
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           VLSDAAVTNPVATASALRKDRPEPVSLVSALAGVFVAGTAVDWRAVVGQS
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          GVRLELPTYPFQRRRFWPKSAGMAIDGR---VGASAGSGILGSGKDLASG
MAB_0939|M.abscessus_ATCC_1997      RRTVELPTYPFQRRRFWPKSSGTAIEG-----GGGLPSGILGRGEDLASG
Mvan_1003|M.vanbaalenii_PYR-1       HRRLPLPTYPFQHRSYWPKTAGIRSDG-------SSGSGLLGSAQDLASG
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           -HFVELPTYAFERRRFWLSGDAVPADAAGLGLQAGEHALLGAVVELPASG
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          DSVYTSRLSVKTQPWLSDHVIYGTVVVPGATYAAMALAAVGTPAHAKDVF
MAB_0939|M.abscessus_ATCC_1997      DSVYISRLSVRSQPWLSDHVIYGTVVVPGATYAAMALAAVGTPARAKDVF
Mvan_1003|M.vanbaalenii_PYR-1       DIVHTSRLSVKTQPWLSDHVIYGTVVVPGATYAAMALAAMPTPARVQEVF
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           GVVLTGRLSLAAQGWLADHAVGGVVIFPGAGFVELAIRAGDEVGCRVVDE
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          FYEPIILPEKSSREVQLTVHPSVDGE-SKFQVHSRPYGERGAEWALNAEG
MAB_0939|M.abscessus_ATCC_1997      FYEPIILPEKSSREVQLTLHPLEDGSGSKFQVHSRPYGERDVDWSLNAEG
Mvan_1003|M.vanbaalenii_PYR-1       FYEPIILGDKDSREVQLMLHRTDDADGWTFEVHSRPYGDRDADWSRNASG
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           LTLAAPLVLPSGGSVAVQVVVGSPDDSGARAVSVYSRGDAGSDWVLHAEG
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          VVASGVGD---SPAAAGDLEDPVDEAIERLNRMRPQELFETFADLELAWG
MAB_0939|M.abscessus_ATCC_1997      TVVTGIGDDAEPAPEAAEPAEPVDAAIERMERMRPMELFEIFADLELAWG
Mvan_1003|M.vanbaalenii_PYR-1       TVAAGVGD-----AAPDAAADPVDNAIERLTRTRPQQLFDAFADNDLAWG
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           SLGSGSPEPA---------TDLSTWPPVGAVEVENADGYQQLAERGYGYG
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          PTWSGSLKSLWLGEGEAIGDILVGAELAEQLGTEPMHPVLMDLCTGVAFP
MAB_0939|M.abscessus_ATCC_1997      PTWSGSLKSLWLGEGEAIGDVLVGEELAEQLGTEPMHPVLMDLCTGVAFP
Mvan_1003|M.vanbaalenii_PYR-1       PAWCSSLRSLWVGTGEAVGDIAVGAELGEHLGREPIHPVLLDLCTGIAGA
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           PAFR-GLNAMWRRGDEVFAEVALPADAGVSVSGFGIHPVMLDAALHAVIL
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          AFPALLAAEQGVNDLYLPLRYGQVSLQEKMPRRFYCRATWHEAPLDSETQ
MAB_0939|M.abscessus_ATCC_1997      AFPALLAAEQGVNDLFLPLRYGQVTLKEKMPRRFYCRARWHESPLDSETQ
Mvan_1003|M.vanbaalenii_PYR-1       ALLAAAAQTDADPELFLPLRYGRVEVRERMPRRFYCRARWQTGGIDSETQ
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           ASDGADDFGVPEGSVLVPFAWQGVTLHAAGASAVRARIAPAGP------S
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          VFDLEYLDRDGRHLGGVREFTVKRAPREALLRGLGGDATRLLYTLGWHEV
MAB_0939|M.abscessus_ATCC_1997      VFDLDYLDRDGRHLGGIREFTVKRAPREALLRGLGGDATRLLYTLGWHEV
Mvan_1003|M.vanbaalenii_PYR-1       VFDLDFLDHDGRNLGGIREFTVKRAPREALLRGLGADATRLIYRVGWRET
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           AVSIELSDGLGLPVLSVASMLARPVTDQQLRAAVSGAGPDRLFGVDWTAQ
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          PVP----ESGDGAAPQGTWLIGGFDELAVSVPGCIPADR-----------
MAB_0939|M.abscessus_ATCC_1997      AVPPVAGEGEESAASIGTWLIAGFDELAAKVPGCIPLNRE----------
Mvan_1003|M.vanbaalenii_PYR-1       SPP---VRDDGALGPSSTWLVAGLDALADDVPGSIRIGFDRIWDPDRDGR
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           PSA--------ELQPVPVRIWGTVESEGDDDPGASVVFES----------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          -----TNPESLRQLLTDAHGRGLPFSGVVWRAAR-SDGDESDAEVAARLE
MAB_0939|M.abscessus_ATCC_1997      -----TDPELLGEVLVAAKERGVPFSGVVWRAAG-PGATESTTESAARLE
Mvan_1003|M.vanbaalenii_PYR-1       VVLDPADDEHWRRLFALADERRAPVAGVVLGVTGRARPEEPSADFAARLE
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           --------------------------------------VPQAGEVVAGVY
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          AEIAELLGAVHTVQ---GGEVKLPGGLWIVTERAVATESGEPVDPVQAAL
MAB_0939|M.abscessus_ATCC_1997      GEIAHLLSAVHTVQNSAQNGVKLPGGLWIVTERAVATESGEPVDPVQAAL
Mvan_1003|M.vanbaalenii_PYR-1       AQIRDVLGAVHSLS---ALGAKPAAGLWIVTERAVAAEAGEPVDPVQSAL
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           AATAAVLEVLRSWL-----SRDGAGQLIITTRGAVALPDEDVTDLAGSAV
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          WGFGRTAINEEPALRCRLVDCDGSPQAVQALAALLSTPVDEPELAVRQGK
MAB_0939|M.abscessus_ATCC_1997      WGFGRTTINEEPALRAKLVDGDGSPEAVQALARLLVTPVDEPEIAVRQGK
Mvan_1003|M.vanbaalenii_PYR-1       WGLGRTLIAEEPGLRCLLVDLDGSEDAGPALARLLGAPGDEPELALRQGR
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           WGLVRSAQTEHP---GRIVLVDTDAQLDEHAVAAVLAAGEPQVLWRNGEV
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          LLASRLLPWSRSGHLTVPRGGDYVLAPTERGAIDNLRLTDSEVPPPA--E
MAB_0939|M.abscessus_ATCC_1997      LLASRLLPWSRTGHLTVPRGSDYVLAPTERGAIDNLRITEKEVPAPD--E
Mvan_1003|M.vanbaalenii_PYR-1       LLVPRLLPWSRSGQLAIPRGTDYVLAPTERGVLDNLRVSETEVTAPP--E
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           YTARVHGSRAVAGLLVPPGDGPWRLGMSTAGTFENLRLEPIPDADAALQP
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          GYVQVRVEAAGLNFRDVLNVLGLYPGDPGPIGGDFAGTVTQLGEGVTGLD
MAB_0939|M.abscessus_ATCC_1997      GYVQVRVEAAGLNFRDVLNVLGLYPGDPGPIGGDFAGIVTQLGEGVTGVE
Mvan_1003|M.vanbaalenii_PYR-1       GHVQVRVEAAGLNFRDVLNALGLYPGDPGPIGGELAGVVTAPGPDVDGFD
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           GHVRVALSAMAANFRDVMIALGLYPDPDAAMGVEGAGVVVETASPDGRFA
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          VGQRVYGSMQGAFASRFNVPGQFLAPIPDGVSAVEAATIPAAALTVR-LS
MAB_0939|M.abscessus_ATCC_1997      VGQRVYGSMQGAFGSRFNVPAQFLAPIPDGISGVEAATIPAAALTVR-LS
Mvan_1003|M.vanbaalenii_PYR-1       VGQRVFGFAVGAFASRVNVPVQFLAPVPEGISAVAAATTPAAVLTAG-LA
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           VGDRVVGLFPEGTGTIAITDHRLLVKIPAGWSDTAAATTSVVFATAFYAL
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          FDWAQVKSGDKVLIHAASGGVGLAAVQMAQQCGAEVYATASTFKRATLRK
MAB_0939|M.abscessus_ATCC_1997      FDWAQLKPGDKVLIHAASGGVGLAAIQMAQQFGAEVFATASTFKRATLRK
Mvan_1003|M.vanbaalenii_PYR-1       FDWAALRAGDRVLIHAASGGVGLAAVQLARQRGATVFATASGYKRPMLRA
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           RDLASVQPGQRILVHAATGGVGMAAVQLARHWGLEVFATASKGKWDTLRA
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          LG--VKHVYDSRTTDFAEQILADTDGAGVDVVLNSLTSEGFIEATLRATA
MAB_0939|M.abscessus_ATCC_1997      LG--VKYVYDSRTTDFADQILADTDGAGVDVVLNSLTSEGFIEATLRATA
Mvan_1003|M.vanbaalenii_PYR-1       MG--VDHVYDSRTTDFADQILADTDGAGVDVVLNSLTNDGFVAATVRATA
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           MGFDEDHIGDSRSLEFEDKFRAATGGRGMDVVLDSLAGE-FVDASLRLVA
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          QHGRFAEIAKRDIWTVEQMAAARPDLAYEIVALDTVMFTEPDRIRDLLTE
MAB_0939|M.abscessus_ATCC_1997      KNGRFAEIAKRDIWTTEQMAQSRPDIAYEIVALDTVMFQEPDRIRVLLTE
Mvan_1003|M.vanbaalenii_PYR-1       RNGRFAEIAKRDIWSPEQMAAARPDIDYEVLALDAVMQQDPDRIQLLLAD
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           PGGVFLEMGKTDIREAAVVAQQHTGVRYRAFDLFEAG---PDHIAQILAE
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          VSAGLRDGAWTPLPAEVYPLTEARAAFRRMQQARHIGKIVVQIPNPLQPQ
MAB_0939|M.abscessus_ATCC_1997      VSEGLAKGEWTPLPAEIYPLTEARTAFRRMQQARHIGKIVCQMPNPLAPR
Mvan_1003|M.vanbaalenii_PYR-1       LADSLARGETAPLPFEAYPLAEATTAFRRMQQARHTGKIILQMPKPLQPH
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           LAALFSEDVLRPLPVTTFDVRRAPAALRYLSQARHVGKVVLTMPDAWAAG
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          PDRSYLITGGLGAIG-LHTAGYLAQLGAGDIVLTSRRAPDAAAQQAIADI
MAB_0939|M.abscessus_ATCC_1997      PDRTYLITGGLGAIG-LHTAAYLAQLGAGDIVLTSRRAPDTDAQRVIGEI
Mvan_1003|M.vanbaalenii_PYR-1       GDRSYLITGGLGALG-LHAAAYLAQLGAGDIVLTGRRMPDAATERAISEI
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           ---TVLITGGTGMAGSALARHVVAHHGVRQLVLVSRRGPDAPGAAELAEE
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          ADRTKARLHVFTADVGVEADVAALLERIRAELPPLAGVAHLAGVLDDALL
MAB_0939|M.abscessus_ATCC_1997      TERSKTRIHVFTADVGAESEVAGLLERIRAELPPLAGVAHLAGVLDDALL
Mvan_1003|M.vanbaalenii_PYR-1       AERYHCRIHTFAADVGDESAVRDLLERIRTELPPLAGVAHLAGVLDDALL
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           LSAFGAQVQVVACDAADRAALAKLIADIPMQHP-LSAVIHTAGALDDAVV
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          SQQSVERFRTALAPKAFGAVHLDRLTRVDDLDFFLVSSSVSSLFGSPGQS
MAB_0939|M.abscessus_ATCC_1997      GQQSVERFRTTLAPKAFGAEYLDRLTKGDDLDFFIVSSSVSSLFGSPGQS
Mvan_1003|M.vanbaalenii_PYR-1       PQQSPERFRTTLAPKAFGAWHLHRLTRDTELEFFIVYSSGSSVLGSPGQA
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           TSLTPERIETVLRAKVDAAWNLHELTRDMDLSAFVMFSSMAGLVGSSGQG
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          NYATANAFLDGLVAQRRAQGLPATGVNFGPWARGGMASSEAAAAN-----
MAB_0939|M.abscessus_ATCC_1997      NYATANALLDGLIAQRRAQGLPATGINFGPWGQGGMASSEAATAN-----
Mvan_1003|M.vanbaalenii_PYR-1       NYATANAVLDGLVAHRKARGLPATGVNWGPWAQGGMATSDAARAN-----
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           NYAAANSFLDGLAVHRQAHGLPAISLGWGLWDQASNMTGGLAAVDFKRFA
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          -------ISAQGLIPLEPSAALTAMAEVVANGTAQATVLKANWQRAAKVL
MAB_0939|M.abscessus_ATCC_1997      -------ISAQGLIPLDPSAALAALAEVVANGTGQATILKANWQRAAKVL
Mvan_1003|M.vanbaalenii_PYR-1       -------LGAQGLIPLEPTAALNALGEIVAHGIASAVVLKANWQRAAKLL
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           RDGIVAMSSDEALGLLDTAMVLGEPFMLPAHIDFAALRVKFDGGTLPPMF
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          GSSRPPILDLVLPSAVGEITGDSELLKQLQEIPVPQRAGFVTEFLQKEVQ
MAB_0939|M.abscessus_ATCC_1997      GSSRPPILDLVLPSAVGEVTGDSELLKQLMEIPVPQRAGFVTEFLQREVQ
Mvan_1003|M.vanbaalenii_PYR-1       GATRPPILDHVLPSAVAAGPGDSALLKQLQDVPEAQRGSFVTEHLQRELQ
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           VDLINAPTRRQVDDSLAAAKSKSALLQRLEGLPEDEQHAILLNLVRSHIA
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          NFLRLAQPP--AATSRFLDLGTDSLMAIELRNRLHSQFGGAFTINATAVF
MAB_0939|M.abscessus_ATCC_1997      NFLRLAQPP--AATSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVF
Mvan_1003|M.vanbaalenii_PYR-1       QILGLAQPP--AATGRFLELGMDSLMAVELRNRLVGQFGSGFTITATAVF
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           TVLGNSSPDAIDPDRAFQELGFDSLTAVEMRNRLKSATG--LALSPTLIF
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          DYPTIGGLAEYLVAQLPDAETPQAAP-------QSESEPGPDVTE-----
MAB_0939|M.abscessus_ATCC_1997      DYPTIGGLAEYLVGQLPDADAESAEAPPAVESAEAESGAGPAAASDAVSE
Mvan_1003|M.vanbaalenii_PYR-1       DYPTIGALAEYLAAQTPESTEEGTEMK------TADPDGQPATVGHADVV
Mb1689|M.bovis_AF2122/97            --------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2471|M.marinum_M               --------------------------------------------------
MAV_3109|M.avium_104                --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           DYPNSAALAGYMHRELVGASPQSDTTAEAPGEAELQRVVASIPVKRLRQA
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          ------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      LKE---------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       LQTS--------------------------------------------
Mb1689|M.bovis_AF2122/97            ------------------------------------------------
Rv1661|M.tuberculosis_H37Rv         ------------------------------------------------
MMAR_2471|M.marinum_M               ------------------------------------------------
MAV_3109|M.avium_104                ------------------------------------------------
MUL_2266|M.ulcerans_Agy99           GVLELLLALANETGGNGQAAVTAETSEEDLADMDLDALVNAAFMNDDE
MLBr_00135|M.leprae_Br4923          ------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      ------------------------------------------------
TH_4621|M.thermoresistible__bu      ------------------------------------------------