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LDVGCGSGRMALPLTGYLNSEGRYAGFDISQKAIAWCQEHITSAHPNFQFEVSDIYNSLYNPKGKYQSLD FRFPYPDASFDVVFLTSVFTHMFPPDVEHYLDEISRVLKPGGRCLCTYFLLNDESLAHIAEGKSAHNFQH EGPGYRTIHKKRPEEAIGLPETFVRDVYGKFGLAVHEPLHYGSWSGREPRLSFQDIVIATKTAS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1498c | - | - | 100% (205) | PROBABLE METHYLTRANSFERASE |
| M. tuberculosis H37Rv | Rv1523 | - | 2e-07 | 32.20% (118) | methyltransferase |
| M. tuberculosis H37Rv | Rv2952 | - | 2e-06 | 33.63% (113) | methyltransferase (methylase) |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1535c | - | 1e-122 | 99.51% (205) | methyltransferase |
| M. gilvum PYR-GCK | Mflv_4269 | - | 8e-05 | 55.00% (40) | methyltransferase type 11 |
| M. leprae Br4923 | MLBr_00130 | - | 7e-06 | 30.97% (113) | hypothetical protein MLBr_00130 |
| M. abscessus ATCC 19977 | MAB_4103c | - | 5e-07 | 31.36% (118) | methyltransferase |
| M. marinum M | MMAR_3170 | - | 1e-06 | 33.90% (118) | methyltransferase |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_0393 | - | 1e-06 | 32.26% (124) | Fmt protein |
| M. thermoresistible (build 8) | TH_1636 | - | 8e-06 | 29.93% (137) | POSSIBLE METHYLTRANSFERASE (METHYLASE) |
| M. ulcerans Agy99 | MUL_2377 | - | 7e-07 | 33.05% (118) | methyltransferase |
| M. vanbaalenii PYR-1 | Mvan_4690 | - | 7e-06 | 28.95% (114) | methyltransferase type 11 |
CLUSTAL 2.0.9 multiple sequence alignment
Rv1498c|M.tuberculosis_H37Rv ----------------------------MLDVGCGSGRMALPLTGYLNSE
Mb1535c|M.bovis_AF2122/97 ----------------------------MLDVGCGSGRMALPLTGYLNSE
MSMEG_0393|M.smegmatis_MC2_155 ---MEARDRVAWRLNIKVAQQAQKLVYRYATRRLKDDDVVFLNYGYEEDP
TH_1636|M.thermoresistible__bu --VRESRDQVFRKLNEKLTQHGQKFIYSYASRRLDDDDVVFLNYGYEEDP
MAB_4103c|M.abscessus_ATCC_199 --MQRSRDWVMFKLNAVFTQRVQKFIYRHATRKLETEDVVFLNYGYEEEP
MMAR_3170|M.marinum_M MAFSPAHRLLARMGSTSIYKRVWRYWYPLMTRGLGADKIAFLNWAYEEDP
MUL_2377|M.ulcerans_Agy99 MAFSPAHRLLARLGSTSIYKRVWRYWYPLMTRGLGADKIAFLNWAYEEDP
MLBr_00130|M.leprae_Br4923 MAFTRIHSFLASAGNTSMYKRVWRFWYPLMTHKLGTDEIMFINWAYEEDP
Mvan_4690|M.vanbaalenii_PYR-1 ----------------------------MVDR---ANVAQVQAWNGDSGR
Mflv_4269|M.gilvum_PYR-GCK ---MTETKEPGAYPDVAVPAPTPHATKEQVEAALHDTKLAQVLYHDWEAE
.
Rv1498c|M.tuberculosis_H37Rv GRYAGFDISQKA-----IAWCQEHITSAHPNFQFEVSDIYNSLYNPKG--
Mb1535c|M.bovis_AF2122/97 GRYAGFDISQKA-----IAWCQEHITSAHPNFQFEVSDIYNSLYNPKG--
MSMEG_0393|M.smegmatis_MC2_155 PMGIPLSESDEL-----NRYSIQLYHSTAAQADVEGKRVLEVGCGHGGGA
TH_1636|M.thermoresistible__bu PMGLPLSETDEP-----NRYSIQLYHRTAGQADLTGKRVLEVGCGHGGGA
MAB_4103c|M.abscessus_ATCC_199 AMGVPLSASDEP-----DRYSIQLYHSTATQADLGGQRVLEVGCGHGGGA
MMAR_3170|M.marinum_M PIDLTLEVSDEP-----NRDHINMYHRTATHVELSGKRVLEVSCGHGGGA
MUL_2377|M.ulcerans_Agy99 PIDLTLEVSDEP-----NRDHINMYHRTATHVELSGKRVLEVSCGHGGGA
MLBr_00130|M.leprae_Br4923 PMALPLEASDEP-----NRAHINLYHRTATQVNLSGKRILEVSCGHGGGA
Mvan_4690|M.vanbaalenii_PYR-1 AWVTLQHVLDRT-----LKPFEDLIVDSVAAAAGPREQILDLGCGTGATT
Mflv_4269|M.gilvum_PYR-GCK TYDDKWSISYDQRCVDYARGRFDAAVPEEVQRELPYDRALELGCGTGFFL
: . : .
Rv1498c|M.tuberculosis_H37Rv -----------KYQSLDFR---------------------------FPYP
Mb1535c|M.bovis_AF2122/97 -----------KYQSLDFR---------------------------FPYP
MSMEG_0393|M.smegmatis_MC2_155 SYLARTFRPA-TYTGLDLNSDGINFCRRRHNIAGL--EFVQGDAQDLPFP
TH_1636|M.thermoresistible__bu SYLMRTLGPM-SYVGLDLNPAGIEFCRKKHRLPGL--EFVVGDAQDLPFG
MAB_4103c|M.abscessus_ATCC_199 SYLVRALQPA-SYTGLDLNPDGISFCRRRHDLPGL--EFVQGDAEDLPFP
MMAR_3170|M.marinum_M SYLTRTLHPA-SYTGLDLNRAGIKLCQRRHNLPGL--DFVRGDAENLPFE
MUL_2377|M.ulcerans_Agy99 SYLTRTLHPA-SYTGLDLNRAGIKLCQRRHNLPGL--DFVRGDAENLPFE
MLBr_00130|M.leprae_Br4923 SYLTRALHPA-SYTGLDLNPAGIKLCQKRHQLPGL--EFVRGDAENLPFD
Mvan_4690|M.vanbaalenii_PYR-1 LALAERLGAHGGCTGIDISEPMIHAARTRARDRNLPVEFVVGDAQSFPFQ
Mflv_4269|M.gilvum_PYR-GCK LNLIQAGVAR-RGSVTDLSPGMVKVATRNGQSLGLDIDGRVADAEGIPYE
*: :*:
Rv1498c|M.tuberculosis_H37Rv DASFDVVFLTSVFTHMFPPDVEHYLDEISRVLKPGGRCLCT---------
Mb1535c|M.bovis_AF2122/97 DASFDVVFLTSVFTHMFPPDVEHYLDEISRVLKPGGRCLCT---------
MSMEG_0393|M.smegmatis_MC2_155 DKNFDAVLN--VESSHLYPRFDVFLTEVARVLRPGGYFLYT---------
TH_1636|M.thermoresistible__bu AESFDAVIN--IESSHLYPRFSRFLSEVARVLRPGGHFLYA---------
MAB_4103c|M.abscessus_ATCC_199 DESFDAVIN--VESSHLYPHFPVFLTEVARVLRPGGNFLYT---------
MMAR_3170|M.marinum_M DESFDVVLN--VEASHCYPHFSRFLAEVVRVLRPGGYLLYT---------
MUL_2377|M.ulcerans_Agy99 DESFDVVLK--VEASHCYPHFSRFLAEVVRVLRPGGYLLYT---------
MLBr_00130|M.leprae_Br4923 NESFDVVIN--IEASHCYPHFPRFLAEVVRVLRPGGHLAYA---------
Mvan_4690|M.vanbaalenii_PYR-1 PNTFDVMVS--RFGVMFFDDPTTAFRNLRRATRPGGRLTFV---------
Mflv_4269|M.gilvum_PYR-GCK DNTFDLVVG--HAVLHHIPDVELSLREVVRVLKPGGRFVFAGEPTTVGNR
.** :. : :: *. :*** .
Rv1498c|M.tuberculosis_H37Rv YFLLNDE--------------SLAHIAEGKSAH-----------NFQHEG
Mb1535c|M.bovis_AF2122/97 YFLLNDE--------------SLAHIAEGKSAH-----------NFQHEG
MSMEG_0393|M.smegmatis_MC2_155 DARPRYD--------------IPEWERALADAP-----------LQMLSQ
TH_1636|M.thermoresistible__bu DARQPHE--------------FAEWEAALAAAP-----------LDMVSA
MAB_4103c|M.abscessus_ATCC_199 DARSVQD--------------VAGWKVALANAP-----------LRMVSE
MMAR_3170|M.marinum_M DLRPSNE--------------IAEWEADLAGSP-----------LRQLSQ
MUL_2377|M.ulcerans_Agy99 DLRPSNE--------------IAEWEADLAGSP-----------LRQLSQ
MLBr_00130|M.leprae_Br4923 DLRPSNK--------------VGEWEVDFANSR-----------LQQLSQ
Mvan_4690|M.vanbaalenii_PYR-1 CWRDPTDNPFMSTAERAAAQLLSDLKPGIAGSPGPFAFADAHRTHSILRA
Mflv_4269|M.gilvum_PYR-GCK YARELSTLTWHAATNIMKLPMLSDWRRPQAELDES---SRAAALEAVVDL
Rv1498c|M.tuberculosis_H37Rv PGYRTIHKKRPEEAIGLPET----------FVRDVYGKFGLAVHEPLH--
Mb1535c|M.bovis_AF2122/97 PGYRTIHKKRPEEAIGLPET----------FVRDVYGKFGLAVHEPLH--
MSMEG_0393|M.smegmatis_MC2_155 RAINFEVVRGMEKNLDALES----------VVDRVAPALLRDWIQKY---
TH_1636|M.thermoresistible__bu RVINAEVVRGMEQILPVWED----------VIERVAPAFLRRRVREF---
MAB_4103c|M.abscessus_ATCC_199 RGINAEVRRGMEKNLARWRY----------VIDRATPAPLRGIVRRF---
MMAR_3170|M.marinum_M REINAEVVRGIEKNSHTSRV----------LVDRNLPAFLRFADR-----
MUL_2377|M.ulcerans_Agy99 REINAEVVRGIEKNSHTSRV----------LVDRNLPAFLRFADR-----
MLBr_00130|M.leprae_Br4923 REINAEVLRGIASNSQKSRD----------LVDRHLPAFLRFAGREFI--
Mvan_4690|M.vanbaalenii_PYR-1 GGWTAVDIRPVDVTCTMQESDLLPYLTQMGPVGRTLRAVDARTRAQVI--
Mflv_4269|M.gilvum_PYR-GCK HTFDPADLERMAANAGAVEVRTASEEFTAAMLGWPVRTFEAAVPPGRLGW
. . :
Rv1498c|M.tuberculosis_H37Rv YGSWSGREPRLSFQDIVIATKTAS-----------------
Mb1535c|M.bovis_AF2122/97 YGSWSGREPHLSFQDIVIATKTAS-----------------
MSMEG_0393|M.smegmatis_MC2_155 GPARRAYEELR-ENTTEYRMYCFVKPAE-------------
TH_1636|M.thermoresistible__bu APARRAWEELRTEGSTEYRMYCFTKPPEHADIP--------
MAB_4103c|M.abscessus_ATCC_199 APAQRAYDDLRAGGSVEYRMYRFVKA---------------
MMAR_3170|M.marinum_M -AVGRQLSRYLEGGELSYRMYCFTKDFAASR----------
MUL_2377|M.ulcerans_Agy99 -AVGRQLSRYLEGGELSYRMYCFTKDFAASR----------
MLBr_00130|M.leprae_Br4923 GVQGTQLSRYLEGGELSYRMYSFAKD---------------
Mvan_4690|M.vanbaalenii_PYR-1 TSLREAYTEFIVDGEVRYPAACWMVDARG------------
Mflv_4269|M.gilvum_PYR-GCK GWAKFAFGSWTTLSWVDANVWRRIVPKGWFYNVMVTGVKPS