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MLTGVTRQKILITGASSGLGAGMARSFAAQGRDLALCARRTDRLTELKAELSQRYPDIKIAVAELDVNDH ERVPKVFAELSDEIGGIDRVIVNAGIGKGARLGSGKLWANKATIETNLVAALVQIETALDMFNQRGSGHL VLISSVLGVKGVPGVKAAYAASKAGVRSLGESLRAEYAQRPIRVTVLEPGYIESEMTAKSASTMLMVDNA TGVKALVAAIEREPGRAAVPWWPWAPLVRLMWVLPPRLTRRFA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0945 | - | - | 100% (253) | short chain dehydrogenase |
| M. tuberculosis H37Rv | Rv2509 | - | 3e-20 | 32.66% (199) | short-chain type dehydrogenase/reductase |
| M. tuberculosis H37Rv | Rv1928c | - | 3e-18 | 29.32% (191) | short chain dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0970 | - | 1e-139 | 99.60% (253) | short chain dehydrogenase |
| M. gilvum PYR-GCK | Mflv_1853 | - | 1e-105 | 77.11% (249) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 1e-17 | 29.47% (190) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_1039 | - | 3e-93 | 68.27% (249) | short chain dehydrogenase |
| M. marinum M | MMAR_4558 | - | 1e-116 | 83.94% (249) | hypothetical protein MMAR_4558 |
| M. avium 104 | MAV_1067 | - | 1e-121 | 86.96% (253) | short chain dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_5544 | - | 1e-105 | 76.71% (249) | short chain dehydrogenase |
| M. thermoresistible (build 8) | TH_3791 | - | 3e-20 | 34.52% (197) | PUTATIVE putative short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_4417 | - | 1e-116 | 83.13% (249) | short chain dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_4881 | - | 1e-106 | 78.31% (249) | short chain dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1853|M.gilvum_PYR-GCK ------------------MTRQKILITGASSGLGAGMARQFAAKGRDLAL
Mvan_4881|M.vanbaalenii_PYR-1 ------------------MTRQKILITGASSGLGAGMARQFAAKGRDLAL
MSMEG_5544|M.smegmatis_MC2_155 ------------------MTRQNILITGASSGLGAGMARQFAARGRNLAL
Rv0945|M.tuberculosis_H37Rv --------------MLTGVTRQKILITGASSGLGAGMARSFAAQGRDLAL
Mb0970|M.bovis_AF2122/97 --------------MLTGVTRQKILITGASSGLGAGMARSFAAQGRDLAL
MMAR_4558|M.marinum_M ------------------MTRQKILITGASSGLGAGMARAFAARGRDLAL
MUL_4417|M.ulcerans_Agy99 ------------------MTRQKILIAGASSGLGAGMARAFAARGRDLAL
MAV_1067|M.avium_104 --------------MLPEMTRQKILITGASSGLGAGMARAFAAKGRDLAL
MAB_1039|M.abscessus_ATCC_1997 ------------------MTRQKILITGASSGLGAEMARQFAAKGRDLAL
MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
TH_3791|M.thermoresistible__bu ----MTANTGASVLDMFRLTGRSAIVTGASSGLGRGFAQTLAAAGATVYA
.. :. :::*.. *:* .*: :.* * :
Mflv_1853|M.gilvum_PYR-GCK CARRLDNLDELRTQLLADFPNIKVAVAALDVNDHEQVPKVFTELSDELGG
Mvan_4881|M.vanbaalenii_PYR-1 CARRLDNLDELKAELLERYPDIKIAVAALDVNDHEQVPKVFNELSEELGG
MSMEG_5544|M.smegmatis_MC2_155 CARRTDRLEELKAEIADRHPYIKVAIAALDVNDHEAVPRVFNELSEELGG
Rv0945|M.tuberculosis_H37Rv CARRTDRLTELKAELSQRYPDIKIAVAELDVNDHERVPKVFAELSDEIGG
Mb0970|M.bovis_AF2122/97 CARRTDRLTELKAELSQRYPDIKIAVAELDVNDHERVPKVFAELSDEIGG
MMAR_4558|M.marinum_M CARRTDRLEELKSELAQKHPEITIAIAELDVNDHDQVPKVFAELRDELGG
MUL_4417|M.ulcerans_Agy99 CARRTDRLEELKSELAQKHPEITIAIAELDVNDHDQVPKVFAELRDELGG
MAV_1067|M.avium_104 CARRADRLDELKAELSQRYPGITVAVAALDVNDHEQVPKVFAELSDELGG
MAB_1039|M.abscessus_ATCC_1997 CARRTEALEELKAELLGANPGIKVAVRALDVTNHESVPVVFGELRDELGG
MLBr_01807|M.leprae_Br4923 THR-------ASVVPDWFFG------VECDVTDNDAIGAAFKAVEEHQGP
TH_3791|M.thermoresistible__bu AARRTDRLETLAAENPAIRA------VTCDVTDEQDRRALVERVVAETGG
* **.:.: . : . *
Mflv_1853|M.gilvum_PYR-GCK IDCVIVNAGIGKGYPLGGGKMWANKATLETNLVAALVQIETALEMFKAAG
Mvan_4881|M.vanbaalenii_PYR-1 IDCVIVNAGIGKGYPLGGGKLWANKATIETNLVAALVQIESALEIFKAAG
MSMEG_5544|M.smegmatis_MC2_155 IDRVIVNAGIGKGWPLGEGKPWANKATLETNLVAGLVQIEAALEMFKKAG
Rv0945|M.tuberculosis_H37Rv IDRVIVNAGIGKGARLGSGKLWANKATIETNLVAALVQIETALDMFNQRG
Mb0970|M.bovis_AF2122/97 IDRVIVNAGIGKGARLGSGKLWANKATIETNLVAALVQIETALDMFNQRG
MMAR_4558|M.marinum_M IDRVIVNAGIGKGAPLGSGKLWANKATIETNLVAALVQIETALEMFHKSG
MUL_4417|M.ulcerans_Agy99 IDRVIVNAGIGKGAPLGSGKLWANKATIETNLVAALVQIETALEMFHKSG
MAV_1067|M.avium_104 IDRVIVNAGIGKGAKLGSGKLWANKATIETNLVSALVQIETALEMFHKNG
MAB_1039|M.abscessus_ATCC_1997 LDRVVVNAGIAKGWHLGGGKSWANIQTIETNLIGALVQIEAALALFKEQG
MLBr_01807|M.leprae_Br4923 VEVLVANAGITSDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQR
TH_3791|M.thermoresistible__bu VDVLVNNAGKPGGPDAVKESADEFASILDLNLAAGFHLSCDVVRANPENH
:: :: *** . . :: ** . : .
Mflv_1853|M.gilvum_PYR-GCK AGHLVLVSSVLGNVGVPG-FKAAYSASKAGVTSLGESLRAEYPSGPIKIT
Mvan_4881|M.vanbaalenii_PYR-1 KGHLVLVASVLGNVGVPG-TKAAYSASKAGVISLGESLRSEYASGPIKIT
MSMEG_5544|M.smegmatis_MC2_155 GGHLVLISSVLGNTGVPG-GKAAYCASKAGMTSLGESLRAEYDKGPIRVT
Rv0945|M.tuberculosis_H37Rv SGHLVLISSVLGVKGVPG-VKAAYAASKAGVRSLGESLRAEYAQRPIRVT
Mb0970|M.bovis_AF2122/97 SGHLVLISSVLGVKGVPG-VKAAYAASKAGVRSLGESLRAEYAQGPIRVT
MMAR_4558|M.marinum_M SGHLVLISSVLASKGVPG-VKAAYAASKAGLSSLGESLRAEYDKGPITVS
MUL_4417|M.ulcerans_Agy99 SGHLVLISSVLASKGVPG-VKAAYAASKAGLSSLGESLRAEYDKSPITVS
MAV_1067|M.avium_104 SGHLVLISSVLGNKGVPG-VKAAYAASKAGLSSLGESLRAEYAKGPIKVS
MAB_1039|M.abscessus_ATCC_1997 YGHLVLISSVTAAKGLPG-TKAAYAASKAGLSSLGESLRSEYARGPIKVS
MLBr_01807|M.leprae_Br4923 FGRYIFMGSVVGLSGVP--GQANYAASKSGLIGMARSLARELGSRSITAN
TH_3791|M.thermoresistible__bu RLSIVNVSSVIGLVSTAPIGGAGYAASKAGVLGLTRELAGQWGRQGIRVN
: :.** . . . * *.***:*: .: ..* : * .
Mflv_1853|M.gilvum_PYR-GCK VLEPGYIESEMTAKSNSTMLMVDNETGVKAMVDAIEKEKGRAVVPGWPWW
Mvan_4881|M.vanbaalenii_PYR-1 VLEPGYIESEMTAKANKTMLMVDNETGVKAMVDAIEKEKGRAVVPGWPWW
MSMEG_5544|M.smegmatis_MC2_155 VVEPGYIESEMTAKANSTMLMVDNETGVRAMVEAIEKEKGRAVVPRWPWA
Rv0945|M.tuberculosis_H37Rv VLEPGYIESEMTAKSASTMLMVDNATGVKALVAAIEREPGRAAVPWWPWA
Mb0970|M.bovis_AF2122/97 VLEPGYIESEMTAKSASTMLMVDNATGVKALVAAIEREPGRAAVPWWPWA
MMAR_4558|M.marinum_M VMEPGYIESEMTAKSGSTMLMVDNETGVNALVSAIEREPGRAAVPWWPWA
MUL_4417|M.ulcerans_Agy99 VMEPGYIESEMTAKSGSTMLMVDNETGVNALVSAIEREPGRAAVPWWPWA
MAV_1067|M.avium_104 VLEPGYIESEMTAKSNSTMLMVDNETGVKALVAAMEREPGRAAVPWWPWA
MAB_1039|M.abscessus_ATCC_1997 TIEPGYIQTDLSAKSPTTPMMVDTLTGVTAMVNAIEKEPGRAAVPRWPWE
MLBr_01807|M.leprae_Br4923 VVAPGFIDTEMTRAMDSKYQEAALQAIP--LGRIGAVEEIAGAVSFLASE
TH_3791|M.thermoresistible__bu ALVPGWFDTEMTDGLFTNERSATWVRRNTMLNRGGREGEVDGALLFLASD
.: **::::::: .. . : ..: .
Mflv_1853|M.gilvum_PYR-GCK PLVEVMKLLPPRFTKYFA--
Mvan_4881|M.vanbaalenii_PYR-1 PLVEVMKVLPPRFAKYFA--
MSMEG_5544|M.smegmatis_MC2_155 PLTQVMRLLPPKYTKRFA--
Rv0945|M.tuberculosis_H37Rv PLVRLMWVLPPRLTRRFA--
Mb0970|M.bovis_AF2122/97 PLVRLMWVLPPRLTRRFA--
MMAR_4558|M.marinum_M PLVQLMRVLPPPLAKKFA--
MUL_4417|M.ulcerans_Agy99 PLVQLMRVLPPPIAKKFA--
MAV_1067|M.avium_104 PLVQLMRVLPPRLTKMFA--
MAB_1039|M.abscessus_ATCC_1997 PVMAVMRLLPPRLAGRLA--
MLBr_01807|M.leprae_Br4923 DAGYISGAVIPVDGGLGMGH
TH_3791|M.thermoresistible__bu ASSYVTGQAIVVDGGWTAR-
: