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TRQKILIAGASSGLGAGMARAFAARGRDLALCARRTDRLEELKSELAQKHPEITIAIAELDVNDHDQVPK VFAELRDELGGIDRVIVNAGIGKGAPLGSGKLWANKATIETNLVAALVQIETALEMFHKSGSGHLVLISS VLASKGVPGVKAAYAASKAGLSSLGESLRAEYDKSPITVSVMEPGYIESEMTAKSGSTMLMVDNETGVNA LVSAIEREPGRAAVPWWPWAPLVQLMRVLPPPIAKKFA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_4417 | - | - | 100% (249) | short chain dehydrogenase |
| M. ulcerans Agy99 | MUL_0819 | adh_1 | 3e-20 | 31.77% (192) | short-chain dehydrogenase Adh_1 |
| M. ulcerans Agy99 | MUL_1491 | fabG1 | 2e-18 | 30.00% (190) | 3-oxoacyl- |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0970 | - | 1e-116 | 83.13% (249) | short chain dehydrogenase |
| M. gilvum PYR-GCK | Mflv_1853 | - | 1e-105 | 75.10% (249) | short chain dehydrogenase |
| M. tuberculosis H37Rv | Rv0945 | - | 1e-116 | 83.13% (249) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 6e-17 | 29.47% (190) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_1039 | - | 2e-93 | 67.87% (249) | short chain dehydrogenase |
| M. marinum M | MMAR_4558 | - | 1e-137 | 98.80% (249) | hypothetical protein MMAR_4558 |
| M. avium 104 | MAV_1067 | - | 1e-122 | 87.55% (249) | short chain dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_5544 | - | 1e-108 | 77.91% (249) | short chain dehydrogenase |
| M. thermoresistible (build 8) | TH_2552 | - | 8e-19 | 33.51% (188) | PUTATIVE putative short-chain dehydrogenase/reductase SDR |
| M. vanbaalenii PYR-1 | Mvan_4881 | - | 1e-105 | 75.10% (249) | short chain dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1853|M.gilvum_PYR-GCK ----MTRQKILITGASS-GLGAGMARQFAAKG--RDLALCARRLDNLDEL
Mvan_4881|M.vanbaalenii_PYR-1 ----MTRQKILITGASS-GLGAGMARQFAAKG--RDLALCARRLDNLDEL
MSMEG_5544|M.smegmatis_MC2_155 ----MTRQNILITGASS-GLGAGMARQFAARG--RNLALCARRTDRLEEL
Mb0970|M.bovis_AF2122/97 MLTGVTRQKILITGASS-GLGAGMARSFAAQG--RDLALCARRTDRLTEL
Rv0945|M.tuberculosis_H37Rv MLTGVTRQKILITGASS-GLGAGMARSFAAQG--RDLALCARRTDRLTEL
MUL_4417|M.ulcerans_Agy99 ----MTRQKILIAGASS-GLGAGMARAFAARG--RDLALCARRTDRLEEL
MMAR_4558|M.marinum_M ----MTRQKILITGASS-GLGAGMARAFAARG--RDLALCARRTDRLEEL
MAV_1067|M.avium_104 MLPEMTRQKILITGASS-GLGAGMARAFAAKG--RDLALCARRADRLDEL
MAB_1039|M.abscessus_ATCC_1997 ----MTRQKILITGASS-GLGAEMARQFAAKG--RDLALCARRTEALEEL
TH_2552|M.thermoresistible__bu ---VLSDSVALITGASG-GIGRVLARRYAQRG--ARVALVARRRDELNVT
MLBr_01807|M.leprae_Br4923 ----MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGH
:: ::.*.. * ::* * :.* . *
Mflv_1853|M.gilvum_PYR-GCK RTQLLADFPNIKVAVA--ALDVNDHEQVPKVFTELSDELGGIDCVIVNAG
Mvan_4881|M.vanbaalenii_PYR-1 KAELLERYPDIKIAVA--ALDVNDHEQVPKVFNELSEELGGIDCVIVNAG
MSMEG_5544|M.smegmatis_MC2_155 KAEIADRHPYIKVAIA--ALDVNDHEAVPRVFNELSEELGGIDRVIVNAG
Mb0970|M.bovis_AF2122/97 KAELSQRYPDIKIAVA--ELDVNDHERVPKVFAELSDEIGGIDRVIVNAG
Rv0945|M.tuberculosis_H37Rv KAELSQRYPDIKIAVA--ELDVNDHERVPKVFAELSDEIGGIDRVIVNAG
MUL_4417|M.ulcerans_Agy99 KSELAQKHPEITIAIA--ELDVNDHDQVPKVFAELRDELGGIDRVIVNAG
MMAR_4558|M.marinum_M KSELAQKHPEITIAIA--ELDVNDHDQVPKVFAELRDELGGIDRVIVNAG
MAV_1067|M.avium_104 KAELSQRYPGITVAVA--ALDVNDHEQVPKVFAELSDELGGIDRVIVNAG
MAB_1039|M.abscessus_ATCC_1997 KAELLGANPGIKVAVR--ALDVTNHESVPVVFGELRDELGGLDRVVVNAG
TH_2552|M.thermoresistible__bu AAAVTEAGG--EALVL--VADIRDETQCADAVAATVARWGRLDVLVNNAA
MLBr_01807|M.leprae_Br4923 RVAVTHRASVVPDWFFGVECDVTDNDAIGAAFKAVEEHQGPVEVLVANAG
: . *: :. .. . * :: :: **.
Mflv_1853|M.gilvum_PYR-GCK IG-KGYPLGGGKMWANKATLETNLVAALVQIETALEMFKA-AGAGHLVLV
Mvan_4881|M.vanbaalenii_PYR-1 IG-KGYPLGGGKLWANKATIETNLVAALVQIESALEIFKA-AGKGHLVLV
MSMEG_5544|M.smegmatis_MC2_155 IG-KGWPLGEGKPWANKATLETNLVAGLVQIEAALEMFKK-AGGGHLVLI
Mb0970|M.bovis_AF2122/97 IG-KGARLGSGKLWANKATIETNLVAALVQIETALDMFNQ-RGSGHLVLI
Rv0945|M.tuberculosis_H37Rv IG-KGARLGSGKLWANKATIETNLVAALVQIETALDMFNQ-RGSGHLVLI
MUL_4417|M.ulcerans_Agy99 IG-KGAPLGSGKLWANKATIETNLVAALVQIETALEMFHK-SGSGHLVLI
MMAR_4558|M.marinum_M IG-KGAPLGSGKLWANKATIETNLVAALVQIETALEMFHK-SGSGHLVLI
MAV_1067|M.avium_104 IG-KGAKLGSGKLWANKATIETNLVSALVQIETALEMFHK-NGSGHLVLI
MAB_1039|M.abscessus_ATCC_1997 IA-KGWHLGGGKSWANIQTIETNLIGALVQIEAALALFKE-QGYGHLVLI
TH_2552|M.thermoresistible__bu VPGSDQSVAEATVDNWNQVLATNLVAPMVLSREALCQAMIPAGSGNIQFL
MLBr_01807|M.leprae_Br4923 IT-SDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIK-QRFGRYIFM
: .. : . .: .** . : . * *. ::
Mflv_1853|M.gilvum_PYR-GCK SSVLGNVGVPGFKAAYSASKAGVTSLGESLRAEYPSGPIKITVLEPGYIE
Mvan_4881|M.vanbaalenii_PYR-1 ASVLGNVGVPGTKAAYSASKAGVISLGESLRSEYASGPIKITVLEPGYIE
MSMEG_5544|M.smegmatis_MC2_155 SSVLGNTGVPGGKAAYCASKAGMTSLGESLRAEYDKGPIRVTVVEPGYIE
Mb0970|M.bovis_AF2122/97 SSVLGVKGVPGVKAAYAASKAGVRSLGESLRAEYAQGPIRVTVLEPGYIE
Rv0945|M.tuberculosis_H37Rv SSVLGVKGVPGVKAAYAASKAGVRSLGESLRAEYAQRPIRVTVLEPGYIE
MUL_4417|M.ulcerans_Agy99 SSVLASKGVPGVKAAYAASKAGLSSLGESLRAEYDKSPITVSVMEPGYIE
MMAR_4558|M.marinum_M SSVLASKGVPGVKAAYAASKAGLSSLGESLRAEYDKGPITVSVMEPGYIE
MAV_1067|M.avium_104 SSVLGNKGVPGVKAAYAASKAGLSSLGESLRAEYAKGPIKVSVLEPGYIE
MAB_1039|M.abscessus_ATCC_1997 SSVTAAKGLPGTKAAYAASKAGLSSLGESLRSEYARGPIKVSTIEPGYIQ
TH_2552|M.thermoresistible__bu SSAAARNVAPG-KAHYAAAKLALSALGQTLALEVGGTGIRVNTLVVGSVE
MLBr_01807|M.leprae_Br4923 GSVVGLSGVPG-QANYAASKSGLIGMARSLARELGSRSITANVVAPGFID
.*. . ** :* *.*:* .: .:..:* * * ..: * ::
Mflv_1853|M.gilvum_PYR-GCK SEMTAKSNSTMLMVDNETGVKAMVDAIE-KEKGRAVVPGWPWWPLVEVMK
Mvan_4881|M.vanbaalenii_PYR-1 SEMTAKANKTMLMVDNETGVKAMVDAIE-KEKGRAVVPGWPWWPLVEVMK
MSMEG_5544|M.smegmatis_MC2_155 SEMTAKANSTMLMVDNETGVRAMVEAIE-KEKGRAVVPRWPWAPLTQVMR
Mb0970|M.bovis_AF2122/97 SEMTAKSASTMLMVDNATGVKALVAAIE-REPGRAAVPWWPWAPLVRLMW
Rv0945|M.tuberculosis_H37Rv SEMTAKSASTMLMVDNATGVKALVAAIE-REPGRAAVPWWPWAPLVRLMW
MUL_4417|M.ulcerans_Agy99 SEMTAKSGSTMLMVDNETGVNALVSAIE-REPGRAAVPWWPWAPLVQLMR
MMAR_4558|M.marinum_M SEMTAKSGSTMLMVDNETGVNALVSAIE-REPGRAAVPWWPWAPLVQLMR
MAV_1067|M.avium_104 SEMTAKSNSTMLMVDNETGVKALVAAME-REPGRAAVPWWPWAPLVQLMR
MAB_1039|M.abscessus_ATCC_1997 TDLSAKSPTTPMMVDTLTGVTAMVNAIE-KEPGRAAVPRWPWEPVMAVMR
TH_2552|M.thermoresistible__bu GELLDRYVARRAAADGVSPDEVLSGLARSTKLGRLISPEEVADVSLWLAS
MLBr_01807|M.leprae_Br4923 TEMTRAMDSKYQEAALQAIPLGRIGAVEEIAGAVSFLASEDAGYISGAVI
:: . : . . .
Mflv_1853|M.gilvum_PYR-GCK LLPPRFTKYFA-----
Mvan_4881|M.vanbaalenii_PYR-1 VLPPRFAKYFA-----
MSMEG_5544|M.smegmatis_MC2_155 LLPPKYTKRFA-----
Mb0970|M.bovis_AF2122/97 VLPPRLTRRFA-----
Rv0945|M.tuberculosis_H37Rv VLPPRLTRRFA-----
MUL_4417|M.ulcerans_Agy99 VLPPPIAKKFA-----
MMAR_4558|M.marinum_M VLPPPLAKKFA-----
MAV_1067|M.avium_104 VLPPRLTKMFA-----
MAB_1039|M.abscessus_ATCC_1997 LLPPRLAGRLA-----
TH_2552|M.thermoresistible__bu DAASAITGQDIFVTGG
MLBr_01807|M.leprae_Br4923 PVDGGLGMGH------