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VTRQKILITGASSGLGAEMARQFAAKGRDLALCARRTEALEELKAELLGANPGIKVAVRALDVTNHESVP VVFGELRDELGGLDRVVVNAGIAKGWHLGGGKSWANIQTIETNLIGALVQIEAALALFKEQGYGHLVLIS SVTAAKGLPGTKAAYAASKAGLSSLGESLRSEYARGPIKVSTIEPGYIQTDLSAKSPTTPMMVDTLTGVT AMVNAIEKEPGRAAVPRWPWEPVMAVMRLLPPRLAGRLA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_1039 | - | - | 100% (249) | short chain dehydrogenase |
| M. abscessus ATCC 19977 | MAB_0607 | - | 1e-18 | 36.32% (190) | short chain dehydrogenase |
| M. abscessus ATCC 19977 | MAB_1526 | - | 2e-18 | 30.13% (229) | short chain dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0970 | - | 3e-94 | 68.67% (249) | short chain dehydrogenase |
| M. gilvum PYR-GCK | Mflv_1853 | - | 5e-92 | 68.72% (243) | short chain dehydrogenase |
| M. tuberculosis H37Rv | Rv0945 | - | 3e-93 | 68.27% (249) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_01740 | - | 9e-17 | 32.29% (192) | short chain dehydrogenase |
| M. marinum M | MMAR_4558 | - | 6e-95 | 69.08% (249) | hypothetical protein MMAR_4558 |
| M. avium 104 | MAV_1067 | - | 1e-95 | 70.68% (249) | short chain dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_5544 | - | 1e-94 | 68.27% (249) | short chain dehydrogenase |
| M. thermoresistible (build 8) | TH_2769 | - | 1e-18 | 29.55% (264) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_4417 | - | 1e-93 | 67.87% (249) | short chain dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_4881 | - | 2e-93 | 69.39% (245) | short chain dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4558|M.marinum_M -------MTRQKILITGASSGLGAGMARAFAARGRDLALCARRTDRLEEL
MUL_4417|M.ulcerans_Agy99 -------MTRQKILIAGASSGLGAGMARAFAARGRDLALCARRTDRLEEL
MAV_1067|M.avium_104 ---MLPEMTRQKILITGASSGLGAGMARAFAAKGRDLALCARRADRLDEL
Mb0970|M.bovis_AF2122/97 ---MLTGVTRQKILITGASSGLGAGMARSFAAQGRDLALCARRTDRLTEL
Rv0945|M.tuberculosis_H37Rv ---MLTGVTRQKILITGASSGLGAGMARSFAAQGRDLALCARRTDRLTEL
Mflv_1853|M.gilvum_PYR-GCK -------MTRQKILITGASSGLGAGMARQFAAKGRDLALCARRLDNLDEL
Mvan_4881|M.vanbaalenii_PYR-1 -------MTRQKILITGASSGLGAGMARQFAAKGRDLALCARRLDNLDEL
MSMEG_5544|M.smegmatis_MC2_155 -------MTRQNILITGASSGLGAGMARQFAARGRNLALCARRTDRLEEL
MAB_1039|M.abscessus_ATCC_1997 -------MTRQKILITGASSGLGAEMARQFAAKGRDLALCARRTEALEEL
MLBr_01740|M.leprae_Br4923 MVKTAQYFVGKRCFVTGAASGIGRATALRLAAYGAELYLTDRHCDGLAQT
TH_2769|M.thermoresistible__bu -------VTGKVVFITGGAAGIGAEVARRLHARGAKVVLTDVDEVALRGM
.. : :::*.::*:* * : * * .: * *
MMAR_4558|M.marinum_M KSELAQKHPEITIAIAELDVNDHDQVPKVFAELRDELGGIDRVIVNAGIG
MUL_4417|M.ulcerans_Agy99 KSELAQKHPEITIAIAELDVNDHDQVPKVFAELRDELGGIDRVIVNAGIG
MAV_1067|M.avium_104 KAELSQRYPGITVAVAALDVNDHEQVPKVFAELSDELGGIDRVIVNAGIG
Mb0970|M.bovis_AF2122/97 KAELSQRYPDIKIAVAELDVNDHERVPKVFAELSDEIGGIDRVIVNAGIG
Rv0945|M.tuberculosis_H37Rv KAELSQRYPDIKIAVAELDVNDHERVPKVFAELSDEIGGIDRVIVNAGIG
Mflv_1853|M.gilvum_PYR-GCK RTQLLADFPNIKVAVAALDVNDHEQVPKVFTELSDELGGIDCVIVNAGIG
Mvan_4881|M.vanbaalenii_PYR-1 KAELLERYPDIKIAVAALDVNDHEQVPKVFNELSEELGGIDCVIVNAGIG
MSMEG_5544|M.smegmatis_MC2_155 KAEIADRHPYIKVAIAALDVNDHEAVPRVFNELSEELGGIDRVIVNAGIG
MAB_1039|M.abscessus_ATCC_1997 KAELLGANPGIKVAVRALDVTNHESVPVVFGELRDELGGLDRVVVNAGIA
MLBr_01740|M.leprae_Br4923 VSEARALGAQVP-EYRALDISDYDEVAAFGADIHARHPSMDIVMNIAGVS
TH_2769|M.thermoresistible__bu LSELGADR----VLTRVADVRDLTAMQAAADAAVERFGGIDVTVANAGVA
:: *: : : . .:* .: **:.
MMAR_4558|M.marinum_M KGAPLGSGKLWANKATIETNLVAALVQIETALEMFHKSG-SGHLVLISSV
MUL_4417|M.ulcerans_Agy99 KGAPLGSGKLWANKATIETNLVAALVQIETALEMFHKSG-SGHLVLISSV
MAV_1067|M.avium_104 KGAKLGSGKLWANKATIETNLVSALVQIETALEMFHKNG-SGHLVLISSV
Mb0970|M.bovis_AF2122/97 KGARLGSGKLWANKATIETNLVAALVQIETALDMFNQRG-SGHLVLISSV
Rv0945|M.tuberculosis_H37Rv KGARLGSGKLWANKATIETNLVAALVQIETALDMFNQRG-SGHLVLISSV
Mflv_1853|M.gilvum_PYR-GCK KGYPLGGGKMWANKATLETNLVAALVQIETALEMFKAAG-AGHLVLVSSV
Mvan_4881|M.vanbaalenii_PYR-1 KGYPLGGGKLWANKATIETNLVAALVQIESALEIFKAAG-KGHLVLVASV
MSMEG_5544|M.smegmatis_MC2_155 KGWPLGEGKPWANKATLETNLVAGLVQIEAALEMFKKAG-GGHLVLISSV
MAB_1039|M.abscessus_ATCC_1997 KGWHLGGGKSWANIQTIETNLIGALVQIEAALALFKEQG-YGHLVLISSV
MLBr_01740|M.leprae_Br4923 VWGTVDRLTHDQWSNVVAINLMGPIHIIETFVPAILAAGRGGHLVNVSSA
TH_2769|M.thermoresistible__bu TYGSVLAVDPAAFKLLIDVNVTGVFHTVRATLPALIDRR--GYVLIVSSL
: : *: . : :.: : : *::: ::*
MMAR_4558|M.marinum_M LASKGVPGVKAAYAASKAGLSSLGESLRAEYDKGPITVSVMEPGYIESEM
MUL_4417|M.ulcerans_Agy99 LASKGVPGVKAAYAASKAGLSSLGESLRAEYDKSPITVSVMEPGYIESEM
MAV_1067|M.avium_104 LGNKGVPGVKAAYAASKAGLSSLGESLRAEYAKGPIKVSVLEPGYIESEM
Mb0970|M.bovis_AF2122/97 LGVKGVPGVKAAYAASKAGVRSLGESLRAEYAQGPIRVTVLEPGYIESEM
Rv0945|M.tuberculosis_H37Rv LGVKGVPGVKAAYAASKAGVRSLGESLRAEYAQRPIRVTVLEPGYIESEM
Mflv_1853|M.gilvum_PYR-GCK LGNVGVPGFKAAYSASKAGVTSLGESLRAEYPSGPIKITVLEPGYIESEM
Mvan_4881|M.vanbaalenii_PYR-1 LGNVGVPGTKAAYSASKAGVISLGESLRSEYASGPIKITVLEPGYIESEM
MSMEG_5544|M.smegmatis_MC2_155 LGNTGVPGGKAAYCASKAGMTSLGESLRAEYDKGPIRVTVVEPGYIESEM
MAB_1039|M.abscessus_ATCC_1997 TAAKGLPGTKAAYAASKAGLSSLGESLRSEYARGPIKVSTIEPGYIQTDL
MLBr_01740|M.leprae_Br4923 AGLVALP-WHAAYSASKYGLRGLSEVLRFDLARYRIGVSVVVPGAVRTPL
TH_2769|M.thermoresistible__bu AAFAAAP-GMAPYDAAKAGVEHFANALRMEVAHQGVDVGSAHMSWIDTAM
. . * *.* *:* *: :.: ** : : : . : : :
MMAR_4558|M.marinum_M TAKSGST-----------------MLMVDNETGVNALVSAIEREP-----
MUL_4417|M.ulcerans_Agy99 TAKSGST-----------------MLMVDNETGVNALVSAIEREP-----
MAV_1067|M.avium_104 TAKSNST-----------------MLMVDNETGVKALVAAMEREP-----
Mb0970|M.bovis_AF2122/97 TAKSAST-----------------MLMVDNATGVKALVAAIEREP-----
Rv0945|M.tuberculosis_H37Rv TAKSAST-----------------MLMVDNATGVKALVAAIEREP-----
Mflv_1853|M.gilvum_PYR-GCK TAKSNST-----------------MLMVDNETGVKAMVDAIEKEK-----
Mvan_4881|M.vanbaalenii_PYR-1 TAKANKT-----------------MLMVDNETGVKAMVDAIEKEK-----
MSMEG_5544|M.smegmatis_MC2_155 TAKANST-----------------MLMVDNETGVRAMVEAIEKEK-----
MAB_1039|M.abscessus_ATCC_1997 SAKSPTT-----------------PMMVDTLTGVTAMVNAIEKEP-----
MLBr_01740|M.leprae_Br4923 VDTIEIAGVDRQDPRFSRWVDRFRGHAVSAERAAEKILAGVAKNRYLIYT
TH_2769|M.thermoresistible__bu VRDTKDDLPSFREMLTSLPG--PLGRTTSVDKCADAFVKGIERRS-----
.. . :: .: :.
MMAR_4558|M.marinum_M --------GRAAVPWWP---------------WAPLVQLMRVLPPPLAKK
MUL_4417|M.ulcerans_Agy99 --------GRAAVPWWP---------------WAPLVQLMRVLPPPIAKK
MAV_1067|M.avium_104 --------GRAAVPWWP---------------WAPLVQLMRVLPPRLTKM
Mb0970|M.bovis_AF2122/97 --------GRAAVPWWP---------------WAPLVRLMWVLPPRLTRR
Rv0945|M.tuberculosis_H37Rv --------GRAAVPWWP---------------WAPLVRLMWVLPPRLTRR
Mflv_1853|M.gilvum_PYR-GCK --------GRAVVPGWP---------------WWPLVEVMKLLPPRFTKY
Mvan_4881|M.vanbaalenii_PYR-1 --------GRAVVPGWP---------------WWPLVEVMKVLPPRFAKY
MSMEG_5544|M.smegmatis_MC2_155 --------GRAVVPRWP---------------WAPLTQVMRLLPPKYTKR
MAB_1039|M.abscessus_ATCC_1997 --------GRAAVPRWP---------------WEPVMAVMRLLPPRLAGR
MLBr_01740|M.leprae_Br4923 SHDIRVLYGFKRLAWWP---------------YGVVMKQVNVVFTRALRP
TH_2769|M.thermoresistible__bu --------SRIYCPQWVGLVRWLKPVLSTRLGQAPILRTAPRLVPQMDAE
. . * : : .
MMAR_4558|M.marinum_M FA---------------------------
MUL_4417|M.ulcerans_Agy99 FA---------------------------
MAV_1067|M.avium_104 FA---------------------------
Mb0970|M.bovis_AF2122/97 FA---------------------------
Rv0945|M.tuberculosis_H37Rv FA---------------------------
Mflv_1853|M.gilvum_PYR-GCK FA---------------------------
Mvan_4881|M.vanbaalenii_PYR-1 FA---------------------------
MSMEG_5544|M.smegmatis_MC2_155 FA---------------------------
MAB_1039|M.abscessus_ATCC_1997 LA---------------------------
MLBr_01740|M.leprae_Br4923 SPATMRCVEPIKVGVYSQPRSGEGGKSGN
TH_2769|M.thermoresistible__bu VAELGRSVSARVAAVRTDDPDSADG----
.