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MLTGVTRQKILITGASSGLGAGMARSFAAQGRDLALCARRTDRLTELKAELSQRYPDIKIAVAELDVNDH ERVPKVFAELSDEIGGIDRVIVNAGIGKGARLGSGKLWANKATIETNLVAALVQIETALDMFNQRGSGHL VLISSVLGVKGVPGVKAAYAASKAGVRSLGESLRAEYAQGPIRVTVLEPGYIESEMTAKSASTMLMVDNA TGVKALVAAIEREPGRAAVPWWPWAPLVRLMWVLPPRLTRRFA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0970 | - | - | 100% (253) | short chain dehydrogenase |
| M. bovis AF2122 / 97 | Mb2537 | - | 2e-20 | 32.66% (199) | putative short-chain type dehydrogenase/reductase |
| M. bovis AF2122 / 97 | Mb1963c | - | 5e-18 | 29.32% (191) | short chain dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1853 | - | 1e-106 | 77.51% (249) | short chain dehydrogenase |
| M. tuberculosis H37Rv | Rv0945 | - | 1e-139 | 99.60% (253) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_00429 | - | 6e-17 | 30.32% (188) | putative oxidoreductase |
| M. abscessus ATCC 19977 | MAB_1039 | - | 4e-94 | 68.67% (249) | short chain dehydrogenase |
| M. marinum M | MMAR_4558 | - | 1e-117 | 84.34% (249) | hypothetical protein MMAR_4558 |
| M. avium 104 | MAV_1067 | - | 1e-122 | 87.35% (253) | short chain dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_5544 | - | 1e-106 | 77.11% (249) | short chain dehydrogenase |
| M. thermoresistible (build 8) | TH_3791 | - | 6e-20 | 34.52% (197) | PUTATIVE putative short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_4417 | - | 1e-116 | 83.13% (249) | short chain dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_4881 | - | 1e-107 | 78.71% (249) | short chain dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0970|M.bovis_AF2122/97 ----------MLTGVTRQKILITGASSGLGAGMARSFAAQGRDLALCARR
Rv0945|M.tuberculosis_H37Rv ----------MLTGVTRQKILITGASSGLGAGMARSFAAQGRDLALCARR
MMAR_4558|M.marinum_M --------------MTRQKILITGASSGLGAGMARAFAARGRDLALCARR
MUL_4417|M.ulcerans_Agy99 --------------MTRQKILIAGASSGLGAGMARAFAARGRDLALCARR
MAV_1067|M.avium_104 ----------MLPEMTRQKILITGASSGLGAGMARAFAAKGRDLALCARR
Mflv_1853|M.gilvum_PYR-GCK --------------MTRQKILITGASSGLGAGMARQFAAKGRDLALCARR
Mvan_4881|M.vanbaalenii_PYR-1 --------------MTRQKILITGASSGLGAGMARQFAAKGRDLALCARR
MSMEG_5544|M.smegmatis_MC2_155 --------------MTRQNILITGASSGLGAGMARQFAARGRNLALCARR
MAB_1039|M.abscessus_ATCC_1997 --------------MTRQKILITGASSGLGAEMARQFAAKGRDLALCARR
TH_3791|M.thermoresistible__bu MTANTGASVLDMFRLTGRSAIVTGASSGLGRGFAQTLAAAGATVYAAARR
MLBr_00429|M.leprae_Br4923 --------MPIPAPSPEARAVVTGASQNIGEALATELAAHGHSLIVIARR
. :::***..:* :* :** * : ***
Mb0970|M.bovis_AF2122/97 TDRLTELKAELSQRYPDIKIAVAELDVNDHERVPKVFAELSDEIGGIDRV
Rv0945|M.tuberculosis_H37Rv TDRLTELKAELSQRYPDIKIAVAELDVNDHERVPKVFAELSDEIGGIDRV
MMAR_4558|M.marinum_M TDRLEELKSELAQKHPEITIAIAELDVNDHDQVPKVFAELRDELGGIDRV
MUL_4417|M.ulcerans_Agy99 TDRLEELKSELAQKHPEITIAIAELDVNDHDQVPKVFAELRDELGGIDRV
MAV_1067|M.avium_104 ADRLDELKAELSQRYPGITVAVAALDVNDHEQVPKVFAELSDELGGIDRV
Mflv_1853|M.gilvum_PYR-GCK LDNLDELRTQLLADFPNIKVAVAALDVNDHEQVPKVFTELSDELGGIDCV
Mvan_4881|M.vanbaalenii_PYR-1 LDNLDELKAELLERYPDIKIAVAALDVNDHEQVPKVFNELSEELGGIDCV
MSMEG_5544|M.smegmatis_MC2_155 TDRLEELKAEIADRHPYIKVAIAALDVNDHEAVPRVFNELSEELGGIDRV
MAB_1039|M.abscessus_ATCC_1997 TEALEELKAELLGANPGIKVAVRALDVTNHESVPVVFGELRDELGGLDRV
TH_3791|M.thermoresistible__bu TDRLETLAAENP------AIRAVTCDVTDEQDRRALVERVVAETGGVDVL
MLBr_00429|M.leprae_Br4923 EDVLVDLAARLADKYR-VAVEVRPADLTDPSERVKLADELTVRP--ISIL
: * * :. : *:.: . : .: . :. :
Mb0970|M.bovis_AF2122/97 IVNAGIGKGARLGSGKLWANKATIETNLVAALVQIETALDMFNQRGSGHL
Rv0945|M.tuberculosis_H37Rv IVNAGIGKGARLGSGKLWANKATIETNLVAALVQIETALDMFNQRGSGHL
MMAR_4558|M.marinum_M IVNAGIGKGAPLGSGKLWANKATIETNLVAALVQIETALEMFHKSGSGHL
MUL_4417|M.ulcerans_Agy99 IVNAGIGKGAPLGSGKLWANKATIETNLVAALVQIETALEMFHKSGSGHL
MAV_1067|M.avium_104 IVNAGIGKGAKLGSGKLWANKATIETNLVSALVQIETALEMFHKNGSGHL
Mflv_1853|M.gilvum_PYR-GCK IVNAGIGKGYPLGGGKMWANKATLETNLVAALVQIETALEMFKAAGAGHL
Mvan_4881|M.vanbaalenii_PYR-1 IVNAGIGKGYPLGGGKLWANKATIETNLVAALVQIESALEIFKAAGKGHL
MSMEG_5544|M.smegmatis_MC2_155 IVNAGIGKGWPLGEGKPWANKATLETNLVAGLVQIEAALEMFKKAGGGHL
MAB_1039|M.abscessus_ATCC_1997 VVNAGIAKGWHLGGGKSWANIQTIETNLIGALVQIEAALALFKEQGYGHL
TH_3791|M.thermoresistible__bu VNNAGKPGGPDAVKESADEFASILDLNLAAGFHLSCDVVRANPENHRLSI
MLBr_00429|M.leprae_Br4923 CANAGTATFGPVSALDPAGEKAQVQLNAVAVHDLTLAVLPGMIERKAGGI
*** . :: * . .: :
Mb0970|M.bovis_AF2122/97 VLISSVLGVKGVPGVK-AAYAASKAGVRSLGESLRAEYAQGPIRVTVLEP
Rv0945|M.tuberculosis_H37Rv VLISSVLGVKGVPGVK-AAYAASKAGVRSLGESLRAEYAQRPIRVTVLEP
MMAR_4558|M.marinum_M VLISSVLASKGVPGVK-AAYAASKAGLSSLGESLRAEYDKGPITVSVMEP
MUL_4417|M.ulcerans_Agy99 VLISSVLASKGVPGVK-AAYAASKAGLSSLGESLRAEYDKSPITVSVMEP
MAV_1067|M.avium_104 VLISSVLGNKGVPGVK-AAYAASKAGLSSLGESLRAEYAKGPIKVSVLEP
Mflv_1853|M.gilvum_PYR-GCK VLVSSVLGNVGVPGFK-AAYSASKAGVTSLGESLRAEYPSGPIKITVLEP
Mvan_4881|M.vanbaalenii_PYR-1 VLVASVLGNVGVPGTK-AAYSASKAGVISLGESLRSEYASGPIKITVLEP
MSMEG_5544|M.smegmatis_MC2_155 VLISSVLGNTGVPGGK-AAYCASKAGMTSLGESLRAEYDKGPIRVTVVEP
MAB_1039|M.abscessus_ATCC_1997 VLISSVTAAKGLPGTK-AAYAASKAGLSSLGESLRSEYARGPIKVSTIEP
TH_3791|M.thermoresistible__bu VNVSSVIGLVSTAPIGGAGYAASKAGVLGLTRELAGQWGRQGIRVNALVP
MLBr_00429|M.leprae_Br4923 LISGSAAGNSPIPYNA--TYAATKAFANTFSESLRGELHGSGVHVTLLAP
: .*. . . *.*:** : ..* .: : :. : *
Mb0970|M.bovis_AF2122/97 GYIESEMTA--------KSASTMLMVDNATGVKALVAAIEREPGRAAVPW
Rv0945|M.tuberculosis_H37Rv GYIESEMTA--------KSASTMLMVDNATGVKALVAAIEREPGRAAVPW
MMAR_4558|M.marinum_M GYIESEMTA--------KSGSTMLMVDNETGVNALVSAIEREPGRAAVPW
MUL_4417|M.ulcerans_Agy99 GYIESEMTA--------KSGSTMLMVDNETGVNALVSAIEREPGRAAVPW
MAV_1067|M.avium_104 GYIESEMTA--------KSNSTMLMVDNETGVKALVAAMEREPGRAAVPW
Mflv_1853|M.gilvum_PYR-GCK GYIESEMTA--------KSNSTMLMVDNETGVKAMVDAIEKEKGRAVVPG
Mvan_4881|M.vanbaalenii_PYR-1 GYIESEMTA--------KANKTMLMVDNETGVKAMVDAIEKEKGRAVVPG
MSMEG_5544|M.smegmatis_MC2_155 GYIESEMTA--------KANSTMLMVDNETGVRAMVEAIEKEKGRAVVPR
MAB_1039|M.abscessus_ATCC_1997 GYIQTDLSA--------KSPTTPMMVDTLTGVTAMVNAIEKEPGRAAVPR
TH_3791|M.thermoresistible__bu GWFDTEMTDG-----LFTNERSATWVRRNTMLNRGGREGEVDGALLFLAS
MLBr_00429|M.leprae_Br4923 GPVRTELPDHDEASLVEKLVPDFLWISTEHTARLSLDALERNK-MRVVPG
* . :::. . : * : :.
Mb0970|M.bovis_AF2122/97 WPWAPLVRLMWVLPPRLTRRFA----------
Rv0945|M.tuberculosis_H37Rv WPWAPLVRLMWVLPPRLTRRFA----------
MMAR_4558|M.marinum_M WPWAPLVQLMRVLPPPLAKKFA----------
MUL_4417|M.ulcerans_Agy99 WPWAPLVQLMRVLPPPIAKKFA----------
MAV_1067|M.avium_104 WPWAPLVQLMRVLPPRLTKMFA----------
Mflv_1853|M.gilvum_PYR-GCK WPWWPLVEVMKLLPPRFTKYFA----------
Mvan_4881|M.vanbaalenii_PYR-1 WPWWPLVEVMKVLPPRFAKYFA----------
MSMEG_5544|M.smegmatis_MC2_155 WPWAPLTQVMRLLPPKYTKRFA----------
MAB_1039|M.abscessus_ATCC_1997 WPWEPVMAVMRLLPPRLAGRLA----------
TH_3791|M.thermoresistible__bu DASSYVTGQAIVVDGGWTAR------------
MLBr_00429|M.leprae_Br4923 LTSKAMSVASRYAPRAIVASIVGNFYKKLGGG
. : .