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MLPEMTRQKILITGASSGLGAGMARAFAAKGRDLALCARRADRLDELKAELSQRYPGITVAVAALDVNDH EQVPKVFAELSDELGGIDRVIVNAGIGKGAKLGSGKLWANKATIETNLVSALVQIETALEMFHKNGSGHL VLISSVLGNKGVPGVKAAYAASKAGLSSLGESLRAEYAKGPIKVSVLEPGYIESEMTAKSNSTMLMVDNE TGVKALVAAMEREPGRAAVPWWPWAPLVQLMRVLPPRLTKMFA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1067 | - | - | 100% (253) | short chain dehydrogenase |
| M. avium 104 | MAV_4982 | - | 1e-21 | 34.91% (212) | short-chain dehydrogenase/reductase SDR |
| M. avium 104 | MAV_2980 | - | 5e-20 | 34.38% (192) | clavaldehyde dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0970 | - | 1e-122 | 87.35% (253) | short chain dehydrogenase |
| M. gilvum PYR-GCK | Mflv_1853 | - | 1e-112 | 80.72% (249) | short chain dehydrogenase |
| M. tuberculosis H37Rv | Rv0945 | - | 1e-122 | 86.96% (253) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 6e-17 | 28.00% (200) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_1039 | - | 1e-95 | 70.68% (249) | short chain dehydrogenase |
| M. marinum M | MMAR_4558 | - | 1e-123 | 88.76% (249) | hypothetical protein MMAR_4558 |
| M. smegmatis MC2 155 | MSMEG_5544 | - | 1e-109 | 78.71% (249) | short chain dehydrogenase |
| M. thermoresistible (build 8) | TH_1383 | - | 9e-21 | 32.20% (205) | PROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE |
| M. ulcerans Agy99 | MUL_4417 | - | 1e-122 | 87.55% (249) | short chain dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_4881 | - | 1e-111 | 80.72% (249) | short chain dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1853|M.gilvum_PYR-GCK ------MTRQKILITGAS-SGLGAGMARQFAAKG--RDLALCARRLDNLD
Mvan_4881|M.vanbaalenii_PYR-1 ------MTRQKILITGAS-SGLGAGMARQFAAKG--RDLALCARRLDNLD
MSMEG_5544|M.smegmatis_MC2_155 ------MTRQNILITGAS-SGLGAGMARQFAARG--RNLALCARRTDRLE
Mb0970|M.bovis_AF2122/97 --MLTGVTRQKILITGAS-SGLGAGMARSFAAQG--RDLALCARRTDRLT
Rv0945|M.tuberculosis_H37Rv --MLTGVTRQKILITGAS-SGLGAGMARSFAAQG--RDLALCARRTDRLT
MMAR_4558|M.marinum_M ------MTRQKILITGAS-SGLGAGMARAFAARG--RDLALCARRTDRLE
MUL_4417|M.ulcerans_Agy99 ------MTRQKILIAGAS-SGLGAGMARAFAARG--RDLALCARRTDRLE
MAV_1067|M.avium_104 --MLPEMTRQKILITGAS-SGLGAGMARAFAAKG--RDLALCARRADRLD
MAB_1039|M.abscessus_ATCC_1997 ------MTRQKILITGAS-SGLGAEMARQFAAKG--RDLALCARRTEALE
TH_1383|M.thermoresistible__bu MPVPEPTPDARAVITGAS-QNIGAALATELAARG--HNLIVTARRAEVLT
MLBr_01807|M.leprae_Br4923 ------MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVAD
. ::.*. . * :: : . * :.: : . *
Mflv_1853|M.gilvum_PYR-GCK ELRTQLLADFPNIKVAVA--ALDVNDHEQVPKVFTELSDELGGIDCVIVN
Mvan_4881|M.vanbaalenii_PYR-1 ELKAELLERYPDIKIAVA--ALDVNDHEQVPKVFNELSEELGGIDCVIVN
MSMEG_5544|M.smegmatis_MC2_155 ELKAEIADRHPYIKVAIA--ALDVNDHEAVPRVFNELSEELGGIDRVIVN
Mb0970|M.bovis_AF2122/97 ELKAELSQRYPDIKIAVA--ELDVNDHERVPKVFAELSDEIGGIDRVIVN
Rv0945|M.tuberculosis_H37Rv ELKAELSQRYPDIKIAVA--ELDVNDHERVPKVFAELSDEIGGIDRVIVN
MMAR_4558|M.marinum_M ELKSELAQKHPEITIAIA--ELDVNDHDQVPKVFAELRDELGGIDRVIVN
MUL_4417|M.ulcerans_Agy99 ELKSELAQKHPEITIAIA--ELDVNDHDQVPKVFAELRDELGGIDRVIVN
MAV_1067|M.avium_104 ELKAELSQRYPGITVAVA--ALDVNDHEQVPKVFAELSDELGGIDRVIVN
MAB_1039|M.abscessus_ATCC_1997 ELKAELLGANPGIKVAVR--ALDVTNHESVPVVFGELRDELGGLDRVVVN
TH_1383|M.thermoresistible__bu ELADRLTDRH-GVTVEVR--PLDLADPEQRGTLCAELAER--EISILCAN
MLBr_01807|M.leprae_Br4923 GHRVAVTHRASVVPDWFFGVECDVTDNDAIGAAFKAVEEHQGPVEVLVAN
: : . *: : : : :. :. : .*
Mflv_1853|M.gilvum_PYR-GCK AGIGKGYPLGGGKMWANKATLETNLVAALVQIETALEMFKAAGAGHLVLV
Mvan_4881|M.vanbaalenii_PYR-1 AGIGKGYPLGGGKLWANKATIETNLVAALVQIESALEIFKAAGKGHLVLV
MSMEG_5544|M.smegmatis_MC2_155 AGIGKGWPLGEGKPWANKATLETNLVAGLVQIEAALEMFKKAGGGHLVLI
Mb0970|M.bovis_AF2122/97 AGIGKGARLGSGKLWANKATIETNLVAALVQIETALDMFNQRGSGHLVLI
Rv0945|M.tuberculosis_H37Rv AGIGKGARLGSGKLWANKATIETNLVAALVQIETALDMFNQRGSGHLVLI
MMAR_4558|M.marinum_M AGIGKGAPLGSGKLWANKATIETNLVAALVQIETALEMFHKSGSGHLVLI
MUL_4417|M.ulcerans_Agy99 AGIGKGAPLGSGKLWANKATIETNLVAALVQIETALEMFHKSGSGHLVLI
MAV_1067|M.avium_104 AGIGKGAKLGSGKLWANKATIETNLVSALVQIETALEMFHKNGSGHLVLI
MAB_1039|M.abscessus_ATCC_1997 AGIAKGWHLGGGKSWANIQTIETNLIGALVQIEAALALFKEQGYGHLVLI
TH_1383|M.thermoresistible__bu AGVATFGPVHKLDPAEEKAQVQLNVLGVHDLVLAVLPGMVQRRAGGILIS
MLBr_01807|M.leprae_Br4923 AGITSDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQRFGRYIFM
**: . : . :: *: . . : * ::
Mflv_1853|M.gilvum_PYR-GCK SSVLGNVGVPGFKAAYSASKAGVTSLGESLRAEYPSGPIKITVLEPGYIE
Mvan_4881|M.vanbaalenii_PYR-1 ASVLGNVGVPGTKAAYSASKAGVISLGESLRSEYASGPIKITVLEPGYIE
MSMEG_5544|M.smegmatis_MC2_155 SSVLGNTGVPGGKAAYCASKAGMTSLGESLRAEYDKGPIRVTVVEPGYIE
Mb0970|M.bovis_AF2122/97 SSVLGVKGVPGVKAAYAASKAGVRSLGESLRAEYAQGPIRVTVLEPGYIE
Rv0945|M.tuberculosis_H37Rv SSVLGVKGVPGVKAAYAASKAGVRSLGESLRAEYAQRPIRVTVLEPGYIE
MMAR_4558|M.marinum_M SSVLASKGVPGVKAAYAASKAGLSSLGESLRAEYDKGPITVSVMEPGYIE
MUL_4417|M.ulcerans_Agy99 SSVLASKGVPGVKAAYAASKAGLSSLGESLRAEYDKSPITVSVMEPGYIE
MAV_1067|M.avium_104 SSVLGNKGVPGVKAAYAASKAGLSSLGESLRAEYAKGPIKVSVLEPGYIE
MAB_1039|M.abscessus_ATCC_1997 SSVTAAKGLPGTKAAYAASKAGLSSLGESLRSEYARGPIKVSTIEPGYIQ
TH_1383|M.thermoresistible__bu GSAAGNSPIPN-NATYAATKAFANTFSESLRGELKDLGVHVTLLAPGPVR
MLBr_01807|M.leprae_Br4923 GSVVGLSGVPG-QANYAASKSGLIGMARSLARELGSRSITANVVAPGFID
.*. . :*. :* *.*:*: :..** * : . : ** :
Mflv_1853|M.gilvum_PYR-GCK SEMTAKSNS--------TMLMVDNETGVKAMVDAIEKEKGRAVVPGWPWW
Mvan_4881|M.vanbaalenii_PYR-1 SEMTAKANK--------TMLMVDNETGVKAMVDAIEKEKGRAVVPGWPWW
MSMEG_5544|M.smegmatis_MC2_155 SEMTAKANS--------TMLMVDNETGVRAMVEAIEKEKGRAVVPRWPWA
Mb0970|M.bovis_AF2122/97 SEMTAKSAS--------TMLMVDNATGVKALVAAIEREPGRAAVPWWPWA
Rv0945|M.tuberculosis_H37Rv SEMTAKSAS--------TMLMVDNATGVKALVAAIEREPGRAAVPWWPWA
MMAR_4558|M.marinum_M SEMTAKSGS--------TMLMVDNETGVNALVSAIEREPGRAAVPWWPWA
MUL_4417|M.ulcerans_Agy99 SEMTAKSGS--------TMLMVDNETGVNALVSAIEREPGRAAVPWWPWA
MAV_1067|M.avium_104 SEMTAKSNS--------TMLMVDNETGVKALVAAMEREPGRAAVPWWPWA
MAB_1039|M.abscessus_ATCC_1997 TDLSAKSPT--------TPMMVDTLTGVTAMVNAIEKEPGRAAVPRWPWE
TH_1383|M.thermoresistible__bu SDLPDPSEASLVDRLVPDFLWISTEHTAKLSLDGLAANKMR-VVPGLTSK
MLBr_01807|M.leprae_Br4923 TEMTRAMDS----------KYQEAALQAIPLGRIGAVEEIAGAVSFLASE
:::. . . : .*. .
Mflv_1853|M.gilvum_PYR-GCK PLVEVMKLLPPRFTKYFA----------
Mvan_4881|M.vanbaalenii_PYR-1 PLVEVMKVLPPRFAKYFA----------
MSMEG_5544|M.smegmatis_MC2_155 PLTQVMRLLPPKYTKRFA----------
Mb0970|M.bovis_AF2122/97 PLVRLMWVLPPRLTRRFA----------
Rv0945|M.tuberculosis_H37Rv PLVRLMWVLPPRLTRRFA----------
MMAR_4558|M.marinum_M PLVQLMRVLPPPLAKKFA----------
MUL_4417|M.ulcerans_Agy99 PLVQLMRVLPPPIAKKFA----------
MAV_1067|M.avium_104 PLVQLMRVLPPRLTKMFA----------
MAB_1039|M.abscessus_ATCC_1997 PVMAVMRLLPPRLAGRLA----------
TH_1383|M.thermoresistible__bu AMSVASGYAPRAIVAPIVGAFYKKLGGG
MLBr_01807|M.leprae_Br4923 DAGYISGAVIPVDGGLGMGH--------