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TRQNILITGASSGLGAGMARQFAARGRNLALCARRTDRLEELKAEIADRHPYIKVAIAALDVNDHEAVPR VFNELSEELGGIDRVIVNAGIGKGWPLGEGKPWANKATLETNLVAGLVQIEAALEMFKKAGGGHLVLISS VLGNTGVPGGKAAYCASKAGMTSLGESLRAEYDKGPIRVTVVEPGYIESEMTAKANSTMLMVDNETGVRA MVEAIEKEKGRAVVPRWPWAPLTQVMRLLPPKYTKRFA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5544 | - | - | 100% (249) | short chain dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_3581 | - | 1e-23 | 33.33% (228) | FabG protein |
| M. smegmatis MC2 155 | MSMEG_0258 | - | 1e-20 | 35.94% (192) | oxidoreductase, short chain dehydrogenase/reductase family |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0970 | - | 1e-106 | 77.11% (249) | short chain dehydrogenase |
| M. gilvum PYR-GCK | Mflv_1853 | - | 1e-112 | 79.92% (249) | short chain dehydrogenase |
| M. tuberculosis H37Rv | Rv0945 | - | 1e-105 | 76.71% (249) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_00429 | - | 1e-19 | 30.00% (230) | putative oxidoreductase |
| M. abscessus ATCC 19977 | MAB_1039 | - | 1e-94 | 68.27% (249) | short chain dehydrogenase |
| M. marinum M | MMAR_4558 | - | 1e-109 | 78.71% (249) | hypothetical protein MMAR_4558 |
| M. avium 104 | MAV_1067 | - | 1e-109 | 78.71% (249) | short chain dehydrogenase |
| M. thermoresistible (build 8) | TH_4326 | - | 5e-21 | 31.71% (246) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_4417 | - | 1e-108 | 77.91% (249) | short chain dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_4881 | - | 1e-112 | 79.12% (249) | short chain dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1853|M.gilvum_PYR-GCK ------MTRQKILITGASSGLGAGMARQFAAKGRDLALCARRLDNLDELR
Mvan_4881|M.vanbaalenii_PYR-1 ------MTRQKILITGASSGLGAGMARQFAAKGRDLALCARRLDNLDELK
MSMEG_5544|M.smegmatis_MC2_155 ------MTRQNILITGASSGLGAGMARQFAARGRNLALCARRTDRLEELK
Mb0970|M.bovis_AF2122/97 --MLTGVTRQKILITGASSGLGAGMARSFAAQGRDLALCARRTDRLTELK
Rv0945|M.tuberculosis_H37Rv --MLTGVTRQKILITGASSGLGAGMARSFAAQGRDLALCARRTDRLTELK
MMAR_4558|M.marinum_M ------MTRQKILITGASSGLGAGMARAFAARGRDLALCARRTDRLEELK
MUL_4417|M.ulcerans_Agy99 ------MTRQKILIAGASSGLGAGMARAFAARGRDLALCARRTDRLEELK
MAV_1067|M.avium_104 --MLPEMTRQKILITGASSGLGAGMARAFAAKGRDLALCARRADRLDELK
MAB_1039|M.abscessus_ATCC_1997 ------MTRQKILITGASSGLGAEMARQFAAKGRDLALCARRTEALEELK
MLBr_00429|M.leprae_Br4923 MPIPAPSPEARAVVTGASQNIGEALATELAAHGHSLIVIARREDVLVDLA
TH_4326|M.thermoresistible__bu ------MPRPVALITGPTSGLGEGFARRYAADGHDLVLVARDVQRLEQLA
.. :::*.:..:* :* ** *:.* : ** : * :*
Mflv_1853|M.gilvum_PYR-GCK TQLLADFPNIKVAVAALDVNDHEQVPKVFTELSDELGGIDCVIVNAGIGK
Mvan_4881|M.vanbaalenii_PYR-1 AELLERYPDIKIAVAALDVNDHEQVPKVFNELSEELGGIDCVIVNAGIGK
MSMEG_5544|M.smegmatis_MC2_155 AEIADRHPYIKVAIAALDVNDHEAVPRVFNELSEELGGIDRVIVNAGIGK
Mb0970|M.bovis_AF2122/97 AELSQRYPDIKIAVAELDVNDHERVPKVFAELSDEIGGIDRVIVNAGIGK
Rv0945|M.tuberculosis_H37Rv AELSQRYPDIKIAVAELDVNDHERVPKVFAELSDEIGGIDRVIVNAGIGK
MMAR_4558|M.marinum_M SELAQKHPEITIAIAELDVNDHDQVPKVFAELRDELGGIDRVIVNAGIGK
MUL_4417|M.ulcerans_Agy99 SELAQKHPEITIAIAELDVNDHDQVPKVFAELRDELGGIDRVIVNAGIGK
MAV_1067|M.avium_104 AELSQRYPGITVAVAALDVNDHEQVPKVFAELSDELGGIDRVIVNAGIGK
MAB_1039|M.abscessus_ATCC_1997 AELLGANPGIKVAVRALDVTNHESVPVVFGELRDELGGLDRVVVNAGIAK
MLBr_00429|M.leprae_Br4923 ARLADKYR-VAVEVRPADLTDPSERVKLADELTVRP--ISILCANAGTAT
TH_4326|M.thermoresistible__bu AELRQSAG-IDVEVLPADLAVAADRAKVADRLADG---VQVLVNNAGFGT
:.: : : : *: : .* :. : *** ..
Mflv_1853|M.gilvum_PYR-GCK GYPLGGGKMWANKATLETNLVAALVQIETALEMFKAAGAGHLVLVSSVLG
Mvan_4881|M.vanbaalenii_PYR-1 GYPLGGGKLWANKATIETNLVAALVQIESALEIFKAAGKGHLVLVASVLG
MSMEG_5544|M.smegmatis_MC2_155 GWPLGEGKPWANKATLETNLVAGLVQIEAALEMFKKAGGGHLVLISSVLG
Mb0970|M.bovis_AF2122/97 GARLGSGKLWANKATIETNLVAALVQIETALDMFNQRGSGHLVLISSVLG
Rv0945|M.tuberculosis_H37Rv GARLGSGKLWANKATIETNLVAALVQIETALDMFNQRGSGHLVLISSVLG
MMAR_4558|M.marinum_M GAPLGSGKLWANKATIETNLVAALVQIETALEMFHKSGSGHLVLISSVLA
MUL_4417|M.ulcerans_Agy99 GAPLGSGKLWANKATIETNLVAALVQIETALEMFHKSGSGHLVLISSVLA
MAV_1067|M.avium_104 GAKLGSGKLWANKATIETNLVSALVQIETALEMFHKNGSGHLVLISSVLG
MAB_1039|M.abscessus_ATCC_1997 GWHLGGGKSWANIQTIETNLIGALVQIEAALALFKEQGYGHLVLISSVTA
MLBr_00429|M.leprae_Br4923 FGPVSALDPAGEKAQVQLNAVAVHDLTLAVLPGMIERKAGGILISGSAAG
TH_4326|M.thermoresistible__bu SGEFWTADPTLLQAQLDVNVTAVMHLTHAALPPMLDAHRGTIINVASVAG
. . :: * . :.* : * :: .*. .
Mflv_1853|M.gilvum_PYR-GCK NVGVPGFKAAYSASKAGVTSLGESLRAEYPSGPIKITVLEPGYIESEMTA
Mvan_4881|M.vanbaalenii_PYR-1 NVGVPGTKAAYSASKAGVISLGESLRSEYASGPIKITVLEPGYIESEMTA
MSMEG_5544|M.smegmatis_MC2_155 NTGVPGGKAAYCASKAGMTSLGESLRAEYDKGPIRVTVVEPGYIESEMTA
Mb0970|M.bovis_AF2122/97 VKGVPGVKAAYAASKAGVRSLGESLRAEYAQGPIRVTVLEPGYIESEMTA
Rv0945|M.tuberculosis_H37Rv VKGVPGVKAAYAASKAGVRSLGESLRAEYAQRPIRVTVLEPGYIESEMTA
MMAR_4558|M.marinum_M SKGVPGVKAAYAASKAGLSSLGESLRAEYDKGPITVSVMEPGYIESEMTA
MUL_4417|M.ulcerans_Agy99 SKGVPGVKAAYAASKAGLSSLGESLRAEYDKSPITVSVMEPGYIESEMTA
MAV_1067|M.avium_104 NKGVPGVKAAYAASKAGLSSLGESLRAEYAKGPIKVSVLEPGYIESEMTA
MAB_1039|M.abscessus_ATCC_1997 AKGLPGTKAAYAASKAGLSSLGESLRSEYARGPIKVSTIEPGYIQTDLSA
MLBr_00429|M.leprae_Br4923 NSPIP-YNATYAATKAFANTFSESLRGELHGSGVHVTLLAPGPVRTELPD
TH_4326|M.thermoresistible__bu LLPG--RGSTYSASKAWVIAFSEGLANGLTGTGVGIHVVCPGFVRTEF--
::*.*:** ::.*.* : : : ** :.:::
Mflv_1853|M.gilvum_PYR-GCK KSNS--------TMLMVDNETGVKAMVDAIEKEKGRAVVPGWPWWPLVEV
Mvan_4881|M.vanbaalenii_PYR-1 KANK--------TMLMVDNETGVKAMVDAIEKEKGRAVVPGWPWWPLVEV
MSMEG_5544|M.smegmatis_MC2_155 KANS--------TMLMVDNETGVRAMVEAIEKEKGRAVVPRWPWAPLTQV
Mb0970|M.bovis_AF2122/97 KSAS--------TMLMVDNATGVKALVAAIEREPGRAAVPWWPWAPLVRL
Rv0945|M.tuberculosis_H37Rv KSAS--------TMLMVDNATGVKALVAAIEREPGRAAVPWWPWAPLVRL
MMAR_4558|M.marinum_M KSGS--------TMLMVDNETGVNALVSAIEREPGRAAVPWWPWAPLVQL
MUL_4417|M.ulcerans_Agy99 KSGS--------TMLMVDNETGVNALVSAIEREPGRAAVPWWPWAPLVQL
MAV_1067|M.avium_104 KSNS--------TMLMVDNETGVKALVAAMEREPGRAAVPWWPWAPLVQL
MAB_1039|M.abscessus_ATCC_1997 KSPT--------TPMMVDTLTGVTAMVNAIEKEPGRAAVPRWPWEPVMAV
MLBr_00429|M.leprae_Br4923 HDEASLVEKLVPDFLWISTEHTARLSLDALERNK-MRVVPGLTSKAMSVA
TH_4326|M.thermoresistible__bu HQRAGIDMSGTPSILYLDVDDVVRTTVARVRKGD-VVIVPGLQYKVLTTV
: : :. . : :.: ** :
Mflv_1853|M.gilvum_PYR-GCK MKLLPPRFTKYFA----------
Mvan_4881|M.vanbaalenii_PYR-1 MKVLPPRFAKYFA----------
MSMEG_5544|M.smegmatis_MC2_155 MRLLPPKYTKRFA----------
Mb0970|M.bovis_AF2122/97 MWVLPPRLTRRFA----------
Rv0945|M.tuberculosis_H37Rv MWVLPPRLTRRFA----------
MMAR_4558|M.marinum_M MRVLPPPLAKKFA----------
MUL_4417|M.ulcerans_Agy99 MRVLPPPIAKKFA----------
MAV_1067|M.avium_104 MRVLPPRLTKMFA----------
MAB_1039|M.abscessus_ATCC_1997 MRLLPPRLAGRLA----------
MLBr_00429|M.leprae_Br4923 SRYAPRAIVASIVGNFYKKLGGG
TH_4326|M.thermoresistible__bu GRLVPRKLVRALTKVVGKGRGRT
* . :.