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DFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGPAAVAMARAVAP YLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSLVSSNLLGFNAPAIAATEAAYE RMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSERLTSAAAAAAGPPSAAGFNLGLANVGANNVG NGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIG FGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYN TGNFNTGNYNTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALE IPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPTVTITVGGPTTT IDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNLASATSGLSGF GNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLHHSVGTMTLNFGLANVGGNNVGGANAGIFNVG LANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIG FGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLN TGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGDLQHRHGEHRQYQHRRFHLRQPQQRPSVAGRQP GSDRPRHRRRHSRNPDCERRREYPDSHTDHRQLHGHRIQRARSSTEHSRHCYFFRTRRYRPLHRPSDTDN RSHTCGHGGWTHYRDQYRRHCGRRRHQHPDYPYSSDSRLRQLDRRTVVGLLQ*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. tuberculosis H37Rv | Rv0305c | PPE6 | - | 100% (963) | PPE FAMILY PROTEIN |
M. tuberculosis H37Rv | Rv0304c | PPE5 | 0.0 | 63.02% (676) | PPE family protein |
M. tuberculosis H37Rv | Rv0355c | PPE8 | 0.0 | 53.53% (835) | PPE family protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0313c | PPE6 | 0.0 | 100.00% (809) | PPE family protein |
M. gilvum PYR-GCK | Mflv_0325 | - | 4e-23 | 34.90% (192) | PPE protein |
M. leprae Br4923 | MLBr_01182 | - | 2e-32 | 46.43% (168) | PPE-family protein |
M. abscessus ATCC 19977 | MAB_0047 | - | 7e-24 | 32.86% (210) | PPE family protein |
M. marinum M | MMAR_1639 | - | 0.0 | 54.78% (869) | PPE family protein |
M. avium 104 | MAV_2910 | - | 1e-49 | 50.72% (207) | PPE family protein |
M. smegmatis MC2 155 | MSMEG_0619 | - | 1e-23 | 40.13% (157) | PPE family protein |
M. thermoresistible (build 8) | TH_3113 | - | 1e-25 | 41.85% (184) | PUTATIVE PPE protein |
M. ulcerans Agy99 | MUL_0965 | - | 1e-157 | 40.13% (937) | PPE family protein |
M. vanbaalenii PYR-1 | Mvan_0415 | - | 4e-26 | 37.86% (206) | PPE protein |
CLUSTAL 2.0.9 multiple sequence alignment Rv0305c|M.tuberculosis_H37Rv -------------MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADE Mb0313c|M.bovis_AF2122/97 -------------MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADE MMAR_1639|M.marinum_M -------------MNFAVLPPEINSARLFSGAGSGPVLAAATAWTGLAAE MUL_0965|M.ulcerans_Agy99 -------------MNFIMLPPEINSARIFAGAGVGPTLAAAAAWDALAAD MAV_2910|M.avium_104 ------------MLDFGAYPPEYNSGRMYVGAGSGPLLAAAAAWDELAAE Mflv_0325|M.gilvum_PYR-GCK MTSPVASLAPVTSPVWMALPPEVHSTMLSSGPGPGSLLAAGVAWQSLSAE Mvan_0415|M.vanbaalenii_PYR-1 ----------MSSPVWMALPPEVHSALLSSGPGPGSMLAAAATWQSLSAE MSMEG_0619|M.smegmatis_MC2_155 ----------MTAPIWMALPPEVHSSLLSSGPGPGSLLAAAGAWQSLSAE MAB_0047|M.abscessus_ATCC_1997 ----------MSAPIWMASPPEVHSALLSAGPGPGALLAAAAQWQALSTQ TH_3113|M.thermoresistible__bu ----------------MALPPEVHSTLLRTGPGPGALSAAADAWRMLSDE MLBr_01182|M.leprae_Br4923 ------------MFDFAALSPETNSTRMYLGPGSSPILTAAAAWVVLAKE .** :* : *.* .. :*. * *: : Rv0305c|M.tuberculosis_H37Rv LAVAASWFGSVTSGLADAAWRGPAAVAMARAVAPYLGWLISATAQAEQAA Mb0313c|M.bovis_AF2122/97 LAVAASWFGSVTSGLADAAWRGPAAVAMARAVAPYLGWLISATAQAEQAA MMAR_1639|M.marinum_M LRSAAAAFLAVTSGLTGNSWRGPAAAVMSDVAASYVGWLSASGAHAEQAA MUL_0965|M.ulcerans_Agy99 LASAAQSFAAITVGLVGEAWQGAAATAMAAAARPYASWLGTAAARAAVTA MAV_2910|M.avium_104 LQSVGASYGSTVETLTTGPWTGPSSIAMAAAAAPYVAWLQATGAQAEQAG Mflv_0325|M.gilvum_PYR-GCK YASAAAELTSILAGVQSGAWEGPSSQQYVAAHTPYLAWLAQQSAVSAATA Mvan_0415|M.vanbaalenii_PYR-1 YAAAAAELSSILADVQAGAWEGPSSEQYVAAHTPYLAWLAQQSAAGAAAA MSMEG_0619|M.smegmatis_MC2_155 YAAAAAELTSVLSAVQAGSWEGPSSEQYVAAHAPYLQWLAQQSANSAAAA MAB_0047|M.abscessus_ATCC_1997 YATAATELTELLGSTVAGSWQGPSAMQYAASHAPYLAWLTQQSAMSATNA TH_3113|M.thermoresistible__bu YRAAAVELAAVVSQTCATAWEGVGADAYAAAHGPYLFWLTDTAAAAAAAG MLBr_01182|M.leprae_Br4923 LTAAAQGLQSAVEALLT-TFEGESAAALAERVTPYEKWLTQNAASAELTA .. .: * .: .* ** * . . Rv0305c|M.tuberculosis_H37Rv AQARVAVATFEAARAATVHPAIVAANRAVLVSLVSSNLLGFNAPAIAATE Mb0313c|M.bovis_AF2122/97 AQARVAVATFEAARAATVHPAIVAANRAVLVSLVSSNLLGFNAPAIAATE MMAR_1639|M.marinum_M EQAKTAAQVFEAARAVTVQPGLVAANRAQLVSLVGSNLFGQNAPAIATAE MUL_0965|M.ulcerans_Agy99 AQANAAAAVFEAAQAATAHPELVAANRNQLVSLVVSNLFGQNAPAIASTE MAV_2910|M.avium_104 AQAKLAAAAYETAFAATVPPPVIAANRALLATLVATNILGQNTPAIAATE Mflv_0325|M.gilvum_PYR-GCK VQHDTAAAAYTTALATMPTLPELALNHTTHAVLVGTNFLGINTIPIALNE Mvan_0415|M.vanbaalenii_PYR-1 AQHEAAAAAYSTALATMPTLPELALNHTTHAVLVATNFLGINTIPIAMTE MSMEG_0619|M.smegmatis_MC2_155 VQHETAAAAYSTALATMPTMAELALNHTMHGVLVATNFFGINTIPIALNE MAB_0047|M.abscessus_ATCC_1997 VLHETSAAAYTTALAAMPTLAELAANHMIHGVLLATNFFGINTIPIALNE TH_3113|M.thermoresistible__bu AQLEAAAAAHASALAAMPTMAELTANRTTHAALVATNFFGVNTIPIAVNE MLBr_01182|M.leprae_Br4923 TQLTVAANAYETAFTMTVPPLMVFVNRAQACLLIMSNIFGQNSTAIAEKE :. .. :* : : *: *: :*::* *: .** * Rv0305c|M.tuberculosis_H37Rv AAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSERLTS--- Mb0313c|M.bovis_AF2122/97 AAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSERLTS--- MMAR_1639|M.marinum_M AQYEQMWAQDVVAMLDYHAGASSVAAALTPLSWPTQTLAGLAAPAAALGS MUL_0965|M.ulcerans_Agy99 AAYDQLWAQDVAAMAGYHSGASAVAAQLAPWQQALRTLQNRVAGATTALP MAV_2910|M.avium_104 AHYMEMWAQDAAAMYAYAA-SSASAAQLTPFTEPPRTTNESAGPLQS--- Mflv_0325|M.gilvum_PYR-GCK ADYVRMWIQAATTMATYQSVSGAALAATPTSAPAPSVLLPGVGEAGR--- Mvan_0415|M.vanbaalenii_PYR-1 ADYVRMWIQAATTMATYQAVSGAALAATPTATPAPFVLAPGVGEAGR--- MSMEG_0619|M.smegmatis_MC2_155 ADYVRMWIQAATTMSTYQAVSGAAVAAAPVSAPAPFLLKPGVGEAGS--- MAB_0047|M.abscessus_ATCC_1997 ADYIRMWIQAATTMGVYQGVSSAALAATTPTQPSPMIMAPG-GEMSR--- TH_3113|M.thermoresistible__bu ADYARMWIQAATTMATYEAVASAAVSATPRTVAPPPILGAGTGESAT--- MLBr_01182|M.leprae_Br4923 AEYTEMWIQDAAAMTSYQASVLEAVGATKAFTAPPLGVNEVGLAQEVV-- * * .:* * ..:* * . . Rv0305c|M.tuberculosis_H37Rv -------------AAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVG Mb0313c|M.bovis_AF2122/97 -------------AAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVG MMAR_1639|M.marinum_M VARSISFNVGFANAGQGNVGAANIGDFNLGLGNIGSGNVGSGNIGGINVG MUL_0965|M.ulcerans_Agy99 PPG--------PAAAAALPGAAAVGFPVLHIGNIGFANLSVGNIGDYNLG MAV_2910|M.avium_104 -------------AAVAQSAAQSGSNTAAHLSQLSATAQPAAQA------ Mflv_0325|M.gilvum_PYR-GCK -------------AAADMSAFAAQPMAAQAGAAFDVSNIIADIIRLYGEV Mvan_0415|M.vanbaalenii_PYR-1 -------------AAADVTAFAAQAQAAEAGSALDLSNIIADLIRAYGEL MSMEG_0619|M.smegmatis_MC2_155 -------------ASASVQQMSAQATAAESGSSLDLSSIISDLLNQYLQG MAB_0047|M.abscessus_ATCC_1997 -------------MSADMMSMAAQPQAAESGSALDSSNNIMDQL------ TH_3113|M.thermoresistible__bu -------------AAITGAHVTAELRAAESRTLLDEINELIDRLFAPLFP MLBr_01182|M.leprae_Br4923 -------------EEVVEEVVEEVVEAEQAISQAALDQAVNEGMEATVVP Rv0305c|M.tuberculosis_H37Rv FGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGSNNVGFG-------- Mb0313c|M.bovis_AF2122/97 FGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGSNNVGFG-------- MMAR_1639|M.marinum_M SGNRGSYNIGPGNLGDYNIGLGNLGDSSVGFGNAGDHNVGVANAGFNNFG MUL_0965|M.ulcerans_Agy99 SGNTGSFNLGSGNIGDASLGSGNAGDSNVGFGNFGSNNVGIG-------- MAV_2910|M.avium_104 AGNAASTTAASTQLTTPSFITN--------WNEFWSVVTGVY-------- Mflv_0325|M.gilvum_PYR-GCK LRFLFEPIFNFLRDP---------------IGNTFALITDFL-------- Mvan_0415|M.vanbaalenii_PYR-1 LRFLFEPIFDFLRDP---------------LGNTIKLITDFL-------- MSMEG_0619|M.smegmatis_MC2_155 VPGG-QAILDFLKDP---------------LGNLGRLLTDFM-------- MAB_0047|M.abscessus_ATCC_1997 --------MRFMTNP---------------LGTLQDMIEDFM-------- TH_3113|M.thermoresistible__bu PG----FADALPDGL---------------LGTLLAPLLPGA-------- MLBr_01182|M.leprae_Br4923 -----------------------------QVDQQVNVDVATP-------- Rv0305c|M.tuberculosis_H37Rv --NTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNS---- Mb0313c|M.bovis_AF2122/97 --NTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNS---- MMAR_1639|M.marinum_M FANTGSNNIGIGLSGDGQVGIGALNSGTGNIGLFNSGTDNIGLFNSGTGN MUL_0965|M.ulcerans_Agy99 --NNGNNNIGIGLNGDDLIGIGALNSGAGNLGFGNSGTNNIGFFNS---- MAV_2910|M.avium_104 -----SPQSWTTIPGGPFLSFG---------------------------- Mflv_0325|M.gilvum_PYR-GCK -----TNPVQALITWGPFLLAVVYQA------------------------ Mvan_0415|M.vanbaalenii_PYR-1 -----TNPAQALITWGPFLAAVAYQA------------------------ MSMEG_0619|M.smegmatis_MC2_155 -----TNPAGALATWWPFLFGVAYQVFFN--------------------- MAB_0047|M.abscessus_ATCC_1997 -----RNPVAAFFAWFPLLFFIAYEAFFI--------------------- TH_3113|M.thermoresistible__bu -----TGDGPPMATIMSFLLMGLSNP------------------------ MLBr_01182|M.leprae_Br4923 --QTAVPDSSSAAAPQLWG------------------------------- Rv0305c|M.tuberculosis_H37Rv -------------------------------------------------- Mb0313c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_1639|M.marinum_M FGIGNSGDYNTGIGNAGATNTGLLNAGLVNTGVGNAGNYNSGGFNAGHTN MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_2910|M.avium_104 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0047|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Rv0305c|M.tuberculosis_H37Rv ----------------GTGNFGIGN------------------------- Mb0313c|M.bovis_AF2122/97 ----------------GTGNFGIGN------------------------- MMAR_1639|M.marinum_M TGSFNSGDYNTGYLNPGNYNTGLANSGDVNTGAFISGNYSNGAFWRGDHQ MUL_0965|M.ulcerans_Agy99 ------GDNNIGFFNSGSGNFGFENAGDINTG-----------FWNGRDT MAV_2910|M.avium_104 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0047|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Rv0305c|M.tuberculosis_H37Rv -------------------------------------------------- Mb0313c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_1639|M.marinum_M GTGISYSVTIPAIPININETYSLDIPFTEDIGPRSIASFVIPRQSVTVIG MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_2910|M.avium_104 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0047|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Rv0305c|M.tuberculosis_H37Rv -------------------------------------------------- Mb0313c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_1639|M.marinum_M IDLLYLGPITIPQINITGPVLSFEIGPATLRLHATGEIGPVEVPIIDIPA MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_2910|M.avium_104 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0047|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Rv0305c|M.tuberculosis_H37Rv -------------------------------------------------- Mb0313c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_1639|M.marinum_M TPGFGNTTTNPSSGFFNTGDGSVSGFGNFAARTSGFLNVGSGSSGVQNLG MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_2910|M.avium_104 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0047|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Rv0305c|M.tuberculosis_H37Rv -------------------------------------------------- Mb0313c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_1639|M.marinum_M ALQSGLANLGDTVSGAFNTGLGVPAHVSGVGNVGSELAGFFRDAAGQAPF MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_2910|M.avium_104 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0047|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Rv0305c|M.tuberculosis_H37Rv -------------------------------------------------- Mb0313c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_1639|M.marinum_M NLGLGNIGFGNVGSANVGSFNVGPANMGDYNIGPGNLGNYNVGLGNLGDS MUL_0965|M.ulcerans_Agy99 -----NTGFG---------------------------------------- MAV_2910|M.avium_104 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0047|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Rv0305c|M.tuberculosis_H37Rv -------------------------------------------------- Mb0313c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_1639|M.marinum_M SVGLANAGDLNVGVANAGSNNFGLANTGSNNIGIGLSGDGQVGFGALNSG MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_2910|M.avium_104 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0047|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Rv0305c|M.tuberculosis_H37Rv ------------------SGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPG Mb0313c|M.bovis_AF2122/97 ------------------SGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPG MMAR_1639|M.marinum_M TGNIGLFNSGADNIGLFNSGTGNFGIGNSGDYNTGIGNAGATNTGLLNAG MUL_0965|M.ulcerans_Agy99 -----------------NSGLSNFGFGNSGVNNVGAGNGGSSNVGLGNAG MAV_2910|M.avium_104 ---------------------QAYAWGQNGQGAAAYLAGPKAISGALAP- Mflv_0325|M.gilvum_PYR-GCK ------------------VSWVGASILYPSLFLLPLLATT--LAIVAGVG Mvan_0415|M.vanbaalenii_PYR-1 ------------------VSWVGASILYPSLLLLPLVATT--LAIVLGVG MSMEG_0619|M.smegmatis_MC2_155 -----------------LVGWPTWGMIFASPFLIPALAALGITGLVLLID MAB_0047|M.abscessus_ATCC_1997 -----------------PFGFTFWGVLLSAPAWLPIVLGLALSALVPPAG TH_3113|M.thermoresistible__bu -----------------AYLFPVLVYLLFTGVVHTTVAVSGMLAQLVPLM MLBr_01182|M.leprae_Br4923 ------------------------GFAQHLSPINDTLSMINNHAGMANAG Rv0305c|M.tuberculosis_H37Rv SYNT----------GNFNTGNYNTGSFNAGNYNTGYFNTGDYNTGVANTG Mb0313c|M.bovis_AF2122/97 SYNT----------GNFNTGNYNTGSFNAGNYNTGYFNTGDYNTGVANTG MMAR_1639|M.marinum_M LVNTGVSNAGNYNSGGFNAGHTNTGSFNSGDYNTGYLNPGNYNTGLVNSG MUL_0965|M.ulcerans_Agy99 LLNT----------GSFNSGKFNTGDFNSGSMNTGYFNSSGHNTGLGNSG MAV_2910|M.avium_104 ----------------LASGGNAVKPMLSSAVGAGQVSGSMGKAALVGS- Mflv_0325|M.gilvum_PYR-GCK QHLL----------SLLNTPPAEEAAEEPAPAQSAPSRPDQQSFPATMSA Mvan_0415|M.vanbaalenii_PYR-1 AYLL----------ENLPAPAEDAPAEEPAASSPAPTRADQPSPAIAVSA MSMEG_0619|M.smegmatis_MC2_155 HVLN----------NPVDVPAEDEAPQEVAAAP----RTDQP-LAVGISP MAB_0047|M.abscessus_ATCC_1997 ---------------IEEPGQEDEPGREPTRIE---RRSPQQDLQLAHVP TH_3113|M.thermoresistible__bu PALL----------PVAVAALGGLAGVWAGLSGLAGLAGLTAVPAADGGA MLBr_01182|M.leprae_Br4923 LSLVN----------GMGSAMKSLAPTTTKAAES---AFKAMGSAVQSTG Rv0305c|M.tuberculosis_H37Rv NVNTGAFIAGNYSNGVLWRGDYQGLIG----------------------- Mb0313c|M.bovis_AF2122/97 NVNTGAFIAGNYSNGVLWRGDYQGLIG----------------------- MMAR_1639|M.marinum_M DVNTGAFISGDYSNGAFWRGDHQGLADISYGITIPEIPAHIEGTIPLAVP MUL_0965|M.ulcerans_Agy99 FTNTGFFNSGD--------------------------------------- MAV_2910|M.avium_104 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0047|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Rv0305c|M.tuberculosis_H37Rv -------------------------------------------------- Mb0313c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_1639|M.marinum_M VTMTSTNTVIHAVTIPVFDAGFLGIPIDAGPVTIPAIVITGPTLTGIIGG MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_2910|M.avium_104 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0047|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Rv0305c|M.tuberculosis_H37Rv -------------------------------------------------- Mb0313c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_1639|M.marinum_M PTSAININTGQHVGPIRLSFLDIPAAPGFGNSTTNPSSGFFNLGQGTVSG MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_2910|M.avium_104 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0047|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Rv0305c|M.tuberculosis_H37Rv -----------------------------------------ADIALEIPA Mb0313c|M.bovis_AF2122/97 -----------------------------------------ADIALEIPA MMAR_1639|M.marinum_M FGNLGARTSGFLNVGSGISGVQNVGALQSGLANLGDTVSGAFNTGLGVPA MUL_0965|M.ulcerans_Agy99 -----------------------------------------LNTGMGSPE MAV_2910|M.avium_104 ---------------------------------------------MSVPQ Mflv_0325|M.gilvum_PYR-GCK ---------------------------------------------PPPPS Mvan_0415|M.vanbaalenii_PYR-1 ---------------------------------------------PPPPS MSMEG_0619|M.smegmatis_MC2_155 ---------------------------------------------AGVPG MAB_0047|M.abscessus_ATCC_1997 ---------------------------------------------SGSPT TH_3113|M.thermoresistible__bu ---------------------------------------------SAAPV MLBr_01182|M.leprae_Br4923 ---------------------------------------------RGLLG Rv0305c|M.tuberculosis_H37Rv IPIN---------------------------------------------- Mb0313c|M.bovis_AF2122/97 IPIN---------------------------------------------- MMAR_1639|M.marinum_M HVSGLGNAGSELAGFFRDATGHARFNLGLGNIGSGNVGSGNIGGANVGSG MUL_0965|M.ulcerans_Agy99 DQS----------------------------------------------- MAV_2910|M.avium_104 G------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK GAPI---------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 SAAA---------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 SAAT---------------------------------------------- MAB_0047|M.abscessus_ATCC_1997 PGGS---------------------------------------------- TH_3113|M.thermoresistible__bu PAGG---------------------------------------------- MLBr_01182|M.leprae_Br4923 SSSG---------------------------------------------- Rv0305c|M.tuberculosis_H37Rv ------------------------------------AQLFSMPIHQVMVM Mb0313c|M.bovis_AF2122/97 ------------------------------------AQLFSMPIHQVMVM MMAR_1639|M.marinum_M NIGDYNIGPANLGDYNIGLGNLGDSSIGLANAGDHNLGVANAGFNNFGFA MUL_0965|M.ulcerans_Agy99 --------------------------------------VANSGFRNAGSG MAV_2910|M.avium_104 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0047|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Rv0305c|M.tuberculosis_H37Rv PGSVMTIP------------GMRLPFTSIVPFVVYYGPVELPQSTLTLPT Mb0313c|M.bovis_AF2122/97 PGSVMTIP------------GMRLPFTSIVPFVVYYGPVELPQSTLTLPT MMAR_1639|M.marinum_M NTGNNNIGIGLSGDGQVGFGALNSGTGNIGLFNSGTDNIGLFNSG-TGNF MUL_0965|M.ulcerans_Agy99 NSGFN-----------------NTGSFSSGFFNSTNSNSEFLNAGGTVNS MAV_2910|M.avium_104 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK ------------------------------------------------AA Mvan_0415|M.vanbaalenii_PYR-1 ------------------------------------------------TV MSMEG_0619|M.smegmatis_MC2_155 ------------------------------------------------AA MAB_0047|M.abscessus_ATCC_1997 ------------------------------------------------TT TH_3113|M.thermoresistible__bu ------------------------------------------------PS MLBr_01182|M.leprae_Br4923 ------------------------------------------------GH Rv0305c|M.tuberculosis_H37Rv VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPG--------------- Mb0313c|M.bovis_AF2122/97 VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPG--------------- MMAR_1639|M.marinum_M GIGNSGDYNTGIGNAGATNTGLLNAGLVNTGVGNAGNYNSGGFNTGSTNT MUL_0965|M.ulcerans_Agy99 GINNSGNTNAGIGNLGDDNFGLFNNGTFNTGAGNS----SG--------- MAV_2910|M.avium_104 -WTEAAPAIRTLAQVLPGNMAAAPAAMAGE-------------------- Mflv_0325|M.gilvum_PYR-GCK NTVSAG-SPPAPGAPAAAAATFVPYVVAGRDPYEG--------------- Mvan_0415|M.vanbaalenii_PYR-1 GTVATG-TAPAPGAPAAATASFVPYAVAGRDPGTG--------------- MSMEG_0619|M.smegmatis_MC2_155 APAPAP-AGTTVAAPAPAAATFVPYAVANRDPGEG--------------- MAB_0047|M.abscessus_ATCC_1997 TTVTSGGSAPPAPAPATATPAYMVYAVQEDPPAAR--------------- TH_3113|M.thermoresistible__bu LPSGSSAPPAPTGSAAPTTGTAPGGAGSPPPAGHS--------------- MLBr_01182|M.leprae_Br4923 VTAQLGRAASIGSLRVPQTWTTASQPVTAATRALS--------------- Rv0305c|M.tuberculosis_H37Rv -------FGNSTTSP---SSGFFNAGAGTASGFGNFGGG----------- Mb0313c|M.bovis_AF2122/97 -------FGNSTTSP---SSGFFNAGAGTASGFGNFGGG----------- MMAR_1639|M.marinum_M GSFNSGDYNTGYLNPGNYNTGLANSGDVNTGAFISGDYSNGAFWRGDHQG MUL_0965|M.ulcerans_Agy99 ----------GAVFP--YTSGLFNSGNGSSGVFNAGDEQ----------- MAV_2910|M.avium_104 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0047|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Rv0305c|M.tuberculosis_H37Rv -------------------------------------------------- Mb0313c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_1639|M.marinum_M LVGFSYAINIPETPGHAEISIPIDIPINGTIGDINTPRVRIPEFPLNVYV MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_2910|M.avium_104 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0047|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Rv0305c|M.tuberculosis_H37Rv -------------------------------------------------- Mb0313c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_1639|M.marinum_M FTPIHVGDVGPIVLPPIRITGPTLTGNIGGPTTSIDIGIGGTLGPAKITI MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_2910|M.avium_104 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0047|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Rv0305c|M.tuberculosis_H37Rv ----------------ASGFWNLASATSG--------LSGFGNVGALGSG Mb0313c|M.bovis_AF2122/97 ----------------ASGFWNLASATSG--------LSGFGNVGALGSG MMAR_1639|M.marinum_M IDIPAAPGFGNSTTSPSSGFFNSGDGSVSGFGNFGDHTSGLVNFGSGNSG MUL_0965|M.ulcerans_Agy99 -----------------SGFFG---------------TSGLVLTGTDGLA MAV_2910|M.avium_104 ------------------------------------------------EG Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0047|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Rv0305c|M.tuberculosis_H37Rv VANVGNTISGLYN-------TSTSNLATPAFNSGLLHHS----------V Mb0313c|M.bovis_AF2122/97 VANVGNTISGLYN-------TSTSNLATPAFNSGLLHHS----------V MMAR_1639|M.marinum_M AQNVGALQSGLANLGDTVSGAFNTGLGVPAHVSGVGNVGSELAGFFRDAT MUL_0965|M.ulcerans_Agy99 ATTT----SGLP------------ALDLPAPNLGIGNAG----------V MAV_2910|M.avium_104 VF-S---------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0047|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Rv0305c|M.tuberculosis_H37Rv GTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFA Mb0313c|M.bovis_AF2122/97 GTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFA MMAR_1639|M.marinum_M GHAPFNLGLGNIGFGNVGSANAGNFNVGSANIGDYNIGPGNLGDYNIGLG MUL_0965|M.ulcerans_Agy99 G----NLGLGNIGDYNLGSGNTGDANFGSGNIGALNLGSGNHGDANLGFG MAV_2910|M.avium_104 -----QMALSSLAGRAVAAAAT-------RPVGGAASAASSLGGVAAEAD Mflv_0325|M.gilvum_PYR-GCK ------FSPTVRDSTGAKAPAGTIPAAASGIAASAAERRKRRRRQKEEIK Mvan_0415|M.vanbaalenii_PYR-1 ------FSPTVRDSTSAKAPASGIPAAASGVAASAAERRKRRRRQKDEIA MSMEG_0619|M.smegmatis_MC2_155 ------FTPTLGNKSQVAAPASGVPAAASGVAASLASRRKRRRKKGAQIE MAB_0047|M.abscessus_ATCC_1997 ------FGPTLNEGSGAKAPAAGISAAAA-AAASARSRARRKRAARIKDP TH_3113|M.thermoresistible__bu ------VPPAPHSAPPVGTSGPPYLIAAQPAPGVARRSAGARRAASIVEP MLBr_01182|M.leprae_Br4923 ---------PARVAVATESESAPLLGGGLPMAPMVPGGGSGTGGVNTALR Rv0305c|M.tuberculosis_H37Rv HAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFG Mb0313c|M.bovis_AF2122/97 HAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFG MMAR_1639|M.marinum_M NLGDSSIGLANAGDHNLGVANAGFNNFGFANTGNNNIGIGLSGDGQVGIG MUL_0965|M.ulcerans_Agy99 NTGDNNIGLFNSGDNNVGFFNSGGANFGLANSGDTNT------------- MAV_2910|M.avium_104 PAAATIIVIPCIEE------------------------------------ Mflv_0325|M.gilvum_PYR-GCK GRGYADAYADYEELPDDGPPEQPAPRVTAST------------------- Mvan_0415|M.vanbaalenii_PYR-1 GRAYADAYADYEPEPDDEPPVRQEPRIAATE------------------- MSMEG_0619|M.smegmatis_MC2_155 ERGYADAYMDYEE-PDEDPAPQPEPRVRASE------------------- MAB_0047|M.abscessus_ATCC_1997 APQFMDMNSSVAPDFSES-AARQTTGVGASA------------------- TH_3113|M.thermoresistible__bu AGSAAAAAAARESAPIRRRRGQKDGLHGHRH------------------- MLBr_01182|M.leprae_Br4923 LQPRAFVMPRNPAAG----------------------------------- Rv0305c|M.tuberculosis_H37Rv SLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFG Mb0313c|M.bovis_AF2122/97 SLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFG MMAR_1639|M.marinum_M ALNSGTGNIGLFNSGTDNIGLFNSGTGNFGIGNSGDYNTGIGNAGATNTG MUL_0965|M.ulcerans_Agy99 ---------GLWNAGSTNTGFGNAGSADFGFGNAGDRNMGFGNAGAAN-- MAV_2910|M.avium_104 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------RGAGPMGFAGTVSRGD--EQAGGLT------------ Mvan_0415|M.vanbaalenii_PYR-1 -------------RGAGPMGFAGTVSRDA--AQAGGLT------------ MSMEG_0619|M.smegmatis_MC2_155 -------------RGSDAMGFTGTVTRHD--VTAAGLT------------ MAB_0047|M.abscessus_ATCC_1997 -------------RGAGRLGFAGTAPAAAGTTAAAGLVERD--------- TH_3113|M.thermoresistible__bu -------------EHQQPASMSAATAPSAAGIRVLGGAG----------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Rv0305c|M.tuberculosis_H37Rv IGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTG Mb0313c|M.bovis_AF2122/97 IGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTG MMAR_1639|M.marinum_M LLNAGLVNTGVGNAGNYNSGGLNAGHTNTGSFNSGDYNTGYLNPGNYNTG MUL_0965|M.ulcerans_Agy99 --------MGAGNSGSYNTGSFNSGTLNTGDFNGGDHNTGWGNSGNTNTG MAV_2910|M.avium_104 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------TLAGDSFGGGPREPMLPGTWDPDATDDRHTDGRDGHDGHDGKE Mvan_0415|M.vanbaalenii_PYR-1 -------TLPGDPFGGGPKAPMLPGTWDPDTEPD------ERHNHHDGKD MSMEG_0619|M.smegmatis_MC2_155 -------TLTGDTFDDRPVTPMLPGTWDGDENPAP------SPDDPEGGP MAB_0047|M.abscessus_ATCC_1997 -------SGTAEALDGARTVPMLPTSWGTDSEHGP-------DRPAEGGS TH_3113|M.thermoresistible__bu --------RISRTRGSVPHAEITPGDPTEPSSPTDR-----AHRPAEPN- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Rv0305c|M.tuberculosis_H37Rv YFNTGDLQH-------------RHGEHR---------------------- Mb0313c|M.bovis_AF2122/97 YFNTGDYNTGMANTGNINTGAFISGNHSNGLLWRGDNQGLIDLAIGVDIP MMAR_1639|M.marinum_M MVNSGDVNTGAFISGDYSNGAFWRGDHQGLVGFSYGFTIPALPAQ----- MUL_0965|M.ulcerans_Agy99 GINSGDLNTG---------------------------------------- MAV_2910|M.avium_104 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK KP------------------------------------------------ Mvan_0415|M.vanbaalenii_PYR-1 SQ------------------------------------------------ MSMEG_0619|M.smegmatis_MC2_155 RR------------------------------------------------ MAB_0047|M.abscessus_ATCC_1997 ST------------------------------------------------ TH_3113|M.thermoresistible__bu -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Rv0305c|M.tuberculosis_H37Rv -------------------------------------------------- Mb0313c|M.bovis_AF2122/97 EIPIVSVDVNIPIHIPITASFTDIVYSGLDLPPNTAVTVIFFGPVDIDPF MMAR_1639|M.marinum_M ----LEAQIPVNIPATATAGDTTIHSATFPAIHFDTFGLLPQSNGTFGPV MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_2910|M.avium_104 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0047|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Rv0305c|M.tuberculosis_H37Rv -------------------------------------------------- Mb0313c|M.bovis_AF2122/97 TVPVIRITGPTPVVMVGGPTTAINIGATVGVDAINIPIIHIPATPGFGNS MMAR_1639|M.marinum_M TLPDITLSGPTFSLLMGGPDTVVGIKAGGVAGPVTFSFIDIPAAPGFGNT MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_2910|M.avium_104 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0047|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Rv0305c|M.tuberculosis_H37Rv -------------------------------------------------- Mb0313c|M.bovis_AF2122/97 TGGLSSGFFNSGAGSASGFGNFGGAASGFMNLVSTTSGMSGFLNVGALGS MMAR_1639|M.marinum_M TATPSSGFFNSGAGSASGFGNSGADNSGLLNL---AFGSSGYQNVGALQS MUL_0965|M.ulcerans_Agy99 ------------------FGSS---------------------------- MAV_2910|M.avium_104 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0047|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Rv0305c|M.tuberculosis_H37Rv -----------QYQHR---------------------RFHLRQPQQRPSV Mb0313c|M.bovis_AF2122/97 GVANVGNTISGIYNVG---------------------TSDLSTPAVNSGL MMAR_1639|M.marinum_M GIANLGNTMSGVYNTGLAVPAHVSGIGNIGHNLAGLLRGTAGQVPVNVGF MUL_0965|M.ulcerans_Agy99 ----------------------------------------ADQAVTNSGF MAV_2910|M.avium_104 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0047|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Rv0305c|M.tuberculosis_H37Rv AGR----------------------------------------------- Mb0313c|M.bovis_AF2122/97 ANIGTNIAGLLRDGAGTAAINLGLANHGNLNVGFASLGGFNFGGATIGHN MMAR_1639|M.marinum_M ANNGAG-------------------------------------------- MUL_0965|M.ulcerans_Agy99 GNNGSG-------------------------------------------- MAV_2910|M.avium_104 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0047|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Rv0305c|M.tuberculosis_H37Rv -------------------------------------------------- Mb0313c|M.bovis_AF2122/97 NVGIGNTGIFDVGLANLGSYNIGFGNLGDDNLGFGNFGSYNIGFGNVGND MMAR_1639|M.marinum_M NVGFGNVGFSNVGSGNIGSFNVGSGNIGDYNIGPGNLGDYNIGLGNLGDS MUL_0965|M.ulcerans_Agy99 NSGFNNTGDTNSGFHNANTSALFSGHSGLLNAG--------------GSQ MAV_2910|M.avium_104 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0047|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Rv0305c|M.tuberculosis_H37Rv ---------------QPGSDRPRHRRRHSR-------------------- Mb0313c|M.bovis_AF2122/97 NLGFANAGGGNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSG MMAR_1639|M.marinum_M SIGFGNAGDHNVGVANAGFNNFGFANTGSNNIGIGLNGDGQVGFGALNSG MUL_0965|M.ulcerans_Agy99 SVGINNTGSFNTVLFNTGFRTAGIANSATN-------------------- MAV_2910|M.avium_104 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0047|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Rv0305c|M.tuberculosis_H37Rv -------NPDCERRREYPDSH--------------------TDHRQLHGH Mb0313c|M.bovis_AF2122/97 SGNIGLFNSGSNNIGFFNSGS--------------------GNFGIANSG MMAR_1639|M.marinum_M TGNIGLFNSGTDNIGLFNSGTGNFGIGNSGDYNTGIGNAGATNTGLLNAG MUL_0965|M.ulcerans_Agy99 --------------------------------------------GLLTA- MAV_2910|M.avium_104 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0047|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Rv0305c|M.tuberculosis_H37Rv RIQRARSSTEHSRHCYF------------------------FRTRRYRP- Mb0313c|M.bovis_AF2122/97 SFNTGIGNTGNTNTGLFNSGDVNTGAFNPGSFNTGSFNTGSFNTGGFNPG MMAR_1639|M.marinum_M LVNTGVGNAGNYNSGGFN--------------------TGSTNTGSFNPG MUL_0965|M.ulcerans_Agy99 --TSGVANSGNNSSGGFN--------------------ANPDQSGFFN-- MAV_2910|M.avium_104 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0047|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Rv0305c|M.tuberculosis_H37Rv -------------------------LHRPSDTDNRSHTCG-HGGWTHYRD Mb0313c|M.bovis_AF2122/97 NTNTG----------YLNIGNYNTGIANTGDVDTGAFITGNYSNGLFLSG MMAR_1639|M.marinum_M DYNTGGLNQGDYNTGYLNSGDYNTGFVNAGDVNTGAFISGNYSNGFFARG MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_2910|M.avium_104 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0047|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Rv0305c|M.tuberculosis_H37Rv QYR-----------------------------RHCGRRRHQHPDYPYSSD Mb0313c|M.bovis_AF2122/97 DYQGLVGLNLVIDMPLPISL-GVNIPIDIPITASAGNITLMGVTIPPTGD MMAR_1639|M.marinum_M DYQNLIGWSYSITVSEFPAYGTLDIPVYIPFTGAIGPITIQEFTIPSLPL MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_2910|M.avium_104 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0047|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Rv0305c|M.tuberculosis_H37Rv SRLRQLDRR------------TVVGLLQ---------------------- Mb0313c|M.bovis_AF2122/97 IVLSSIAGQRAHFGPITIPNITVVGPTTTVAIGGPNTAITITGGG----- MMAR_1639|M.marinum_M DALVYINGTPIPIFYDFGPITVDETTTDPIALNFVWDQLYHYEVGPRTFG MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_2910|M.avium_104 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0047|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Rv0305c|M.tuberculosis_H37Rv -------------------------------------------------- Mb0313c|M.bovis_AF2122/97 ----------AIRIPLISIPAAPGFGNSTTNPSSGFFNTGAGGASGFGNF MMAR_1639|M.marinum_M PYEIPLFSFPGPGFANSTTSPSSGFFNSGTGPTSGFFNSGAGSLSGLINL MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_2910|M.avium_104 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0047|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Rv0305c|M.tuberculosis_H37Rv -------------------------------------------------- Mb0313c|M.bovis_AF2122/97 GGANSGFWNLASATSGASGLLNVGALGSGLANVGTTVSGFYNTSTSDLAT MMAR_1639|M.marinum_M GANNSGFANTGIGGLGNSGFINDGALQSGMANVGNTISGIYNSTTLDPTA MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_2910|M.avium_104 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0047|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Rv0305c|M.tuberculosis_H37Rv -------------------------------------------------- Mb0313c|M.bovis_AF2122/97 PAFNSGLANISTSIAGLLRDSTGTMVLNLGLANHGTLNVGIANLGDYNIG MMAR_1639|M.marinum_M VANVSGIANTGVDLAGVFRGAS--RIHNLGFANLGIANLGSANIGDLNLG MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_2910|M.avium_104 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0047|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Rv0305c|M.tuberculosis_H37Rv -------------------------------------------------- Mb0313c|M.bovis_AF2122/97 FANLGSANFGSANIGGNNIGGANTGIFDIGLANLGSYNIGFGNFGDDNLG MMAR_1639|M.marinum_M GANFGSANIGSGNIGFGNVGGGNVGSLNLGFGNLGDHNIGPGNLGDYNIG MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_2910|M.avium_104 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0047|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Rv0305c|M.tuberculosis_H37Rv -------------------------------------------------- Mb0313c|M.bovis_AF2122/97 FGNLGSYNVGFGNLGNDNLGFANTGSNNIGFANTGSNNIGIGLTGDGQIG MMAR_1639|M.marinum_M LGNLGDSNVGFGNAGDHNVGVGNAGFNNFGFANTGSNNIGIGLSGDGQVG MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_2910|M.avium_104 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0047|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Rv0305c|M.tuberculosis_H37Rv -------------------------------------------------- Mb0313c|M.bovis_AF2122/97 FGSLNSGSGNIGLFNSGSGNIGFFNSGNGNVGIGNTGTANFGLGNTGSTN MMAR_1639|M.marinum_M FGALNSGTGNIGLFNSGTDNIGLFNSGTGNIGLFNSGTGSFGIGNSGNYN MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_2910|M.avium_104 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0047|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Rv0305c|M.tuberculosis_H37Rv -------------------------------------------------- Mb0313c|M.bovis_AF2122/97 TGFFNSGDVNTGIGNTGSFNTGSFNPGDSNTGDFNPGSYNTGLGNTGDVD MMAR_1639|M.marinum_M TGIGNAGATNTGLFNTGLVNTGVGNAGNYNSGGFNTGSTNTGSFNSGDHN MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_2910|M.avium_104 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0047|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Rv0305c|M.tuberculosis_H37Rv -------------------------------------------------- Mb0313c|M.bovis_AF2122/97 TGAFISGSYSNGFLWSGNYQGLIGLHAALAIPEIALTFGVDIPIHIPINI MMAR_1639|M.marinum_M TGYLNSGDYNTGLANSGDVN-----TGAFISGNYSNGFFVDGDHQGLIDG MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_2910|M.avium_104 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0047|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Rv0305c|M.tuberculosis_H37Rv -------------------------------------------------- Mb0313c|M.bovis_AF2122/97 DAGVVTLQGFSIVAAENNIDFTPIIIPTINITLPTAAITVGGPTTSIGIT MMAR_1639|M.marinum_M TPGFFNST------------------------------------------ MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_2910|M.avium_104 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0047|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Rv0305c|M.tuberculosis_H37Rv -------------------------------------------------- Mb0313c|M.bovis_AF2122/97 ASAGIGSITIPIIDIPATSGFGNSTTSPSSGFFNSGAGSASGFLNVVAGA MMAR_1639|M.marinum_M --------------TNPSSGLLNSGEGSESGVGNYGVGNSGFLNFASVTG MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_2910|M.avium_104 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0047|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Rv0305c|M.tuberculosis_H37Rv -------------------------------------------------- Mb0313c|M.bovis_AF2122/97 SGISGYLNVGALGSGVTNVGHTVSGFYNASALDLVTPAFASGLMRDGMGT MMAR_1639|M.marinum_M AGSSGLLNVGALQSGILNLGSTISGFG---NTGSVTPAFVSGVANAGTRL MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_2910|M.avium_104 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0047|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Rv0305c|M.tuberculosis_H37Rv ------------------------------------------------- Mb0313c|M.bovis_AF2122/97 MTLNLGLANLGSNNAGFGNTGIFDVGVANLGNYNIGFGNFGDDNLALPT MMAR_1639|M.marinum_M SGFFFRGTGP--------------------------------------- MUL_0965|M.ulcerans_Agy99 ------------------------------------------------- MAV_2910|M.avium_104 ------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK ------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 ------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 ------------------------------------------------- MAB_0047|M.abscessus_ATCC_1997 ------------------------------------------------- TH_3113|M.thermoresistible__bu ------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------