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M. tuberculosis H37Rv Rv0305c (PPE6)

annotation: PPE FAMILY PROTEIN
coordinates: 372820 - 375711
length: 963

DFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGPAAVAMARAVAP
YLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSLVSSNLLGFNAPAIAATEAAYE
RMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSERLTSAAAAAAGPPSAAGFNLGLANVGANNVG
NGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIG
FGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYN
TGNFNTGNYNTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALE
IPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPTVTITVGGPTTT
IDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNLASATSGLSGF
GNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLHHSVGTMTLNFGLANVGGNNVGGANAGIFNVG
LANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIG
FGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLN
TGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGDLQHRHGEHRQYQHRRFHLRQPQQRPSVAGRQP
GSDRPRHRRRHSRNPDCERRREYPDSHTDHRQLHGHRIQRARSSTEHSRHCYFFRTRRYRPLHRPSDTDN
RSHTCGHGGWTHYRDQYRRHCGRRRHQHPDYPYSSDSRLRQLDRRTVVGLLQ*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv0305cPPE6-100% (963)PPE FAMILY PROTEIN
M. tuberculosis H37RvRv0304cPPE50.063.02% (676) PPE family protein
M. tuberculosis H37RvRv0355cPPE80.053.53% (835) PPE family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0313cPPE60.0100.00% (809) PPE family protein
M. gilvum PYR-GCKMflv_0325-4e-2334.90% (192) PPE protein
M. leprae Br4923MLBr_01182-2e-3246.43% (168) PPE-family protein
M. abscessus ATCC 19977MAB_0047-7e-2432.86% (210) PPE family protein
M. marinum MMMAR_1639-0.054.78% (869) PPE family protein
M. avium 104MAV_2910-1e-4950.72% (207) PPE family protein
M. smegmatis MC2 155MSMEG_0619-1e-2340.13% (157) PPE family protein
M. thermoresistible (build 8)TH_3113-1e-2541.85% (184) PUTATIVE PPE protein
M. ulcerans Agy99MUL_0965-1e-15740.13% (937) PPE family protein
M. vanbaalenii PYR-1Mvan_0415-4e-2637.86% (206) PPE protein

CLUSTAL 2.0.9 multiple sequence alignment


Rv0305c|M.tuberculosis_H37Rv        -------------MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADE
Mb0313c|M.bovis_AF2122/97           -------------MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADE
MMAR_1639|M.marinum_M               -------------MNFAVLPPEINSARLFSGAGSGPVLAAATAWTGLAAE
MUL_0965|M.ulcerans_Agy99           -------------MNFIMLPPEINSARIFAGAGVGPTLAAAAAWDALAAD
MAV_2910|M.avium_104                ------------MLDFGAYPPEYNSGRMYVGAGSGPLLAAAAAWDELAAE
Mflv_0325|M.gilvum_PYR-GCK          MTSPVASLAPVTSPVWMALPPEVHSTMLSSGPGPGSLLAAGVAWQSLSAE
Mvan_0415|M.vanbaalenii_PYR-1       ----------MSSPVWMALPPEVHSALLSSGPGPGSMLAAAATWQSLSAE
MSMEG_0619|M.smegmatis_MC2_155      ----------MTAPIWMALPPEVHSSLLSSGPGPGSLLAAAGAWQSLSAE
MAB_0047|M.abscessus_ATCC_1997      ----------MSAPIWMASPPEVHSALLSAGPGPGALLAAAAQWQALSTQ
TH_3113|M.thermoresistible__bu      ----------------MALPPEVHSTLLRTGPGPGALSAAADAWRMLSDE
MLBr_01182|M.leprae_Br4923          ------------MFDFAALSPETNSTRMYLGPGSSPILTAAAAWVVLAKE
                                                       .** :*  :  *.* ..  :*.  *  *: :

Rv0305c|M.tuberculosis_H37Rv        LAVAASWFGSVTSGLADAAWRGPAAVAMARAVAPYLGWLISATAQAEQAA
Mb0313c|M.bovis_AF2122/97           LAVAASWFGSVTSGLADAAWRGPAAVAMARAVAPYLGWLISATAQAEQAA
MMAR_1639|M.marinum_M               LRSAAAAFLAVTSGLTGNSWRGPAAAVMSDVAASYVGWLSASGAHAEQAA
MUL_0965|M.ulcerans_Agy99           LASAAQSFAAITVGLVGEAWQGAAATAMAAAARPYASWLGTAAARAAVTA
MAV_2910|M.avium_104                LQSVGASYGSTVETLTTGPWTGPSSIAMAAAAAPYVAWLQATGAQAEQAG
Mflv_0325|M.gilvum_PYR-GCK          YASAAAELTSILAGVQSGAWEGPSSQQYVAAHTPYLAWLAQQSAVSAATA
Mvan_0415|M.vanbaalenii_PYR-1       YAAAAAELSSILADVQAGAWEGPSSEQYVAAHTPYLAWLAQQSAAGAAAA
MSMEG_0619|M.smegmatis_MC2_155      YAAAAAELTSVLSAVQAGSWEGPSSEQYVAAHAPYLQWLAQQSANSAAAA
MAB_0047|M.abscessus_ATCC_1997      YATAATELTELLGSTVAGSWQGPSAMQYAASHAPYLAWLTQQSAMSATNA
TH_3113|M.thermoresistible__bu      YRAAAVELAAVVSQTCATAWEGVGADAYAAAHGPYLFWLTDTAAAAAAAG
MLBr_01182|M.leprae_Br4923          LTAAAQGLQSAVEALLT-TFEGESAAALAERVTPYEKWLTQNAASAELTA
                                       ..             .: * .:        .*  **    * .   .

Rv0305c|M.tuberculosis_H37Rv        AQARVAVATFEAARAATVHPAIVAANRAVLVSLVSSNLLGFNAPAIAATE
Mb0313c|M.bovis_AF2122/97           AQARVAVATFEAARAATVHPAIVAANRAVLVSLVSSNLLGFNAPAIAATE
MMAR_1639|M.marinum_M               EQAKTAAQVFEAARAVTVQPGLVAANRAQLVSLVGSNLFGQNAPAIATAE
MUL_0965|M.ulcerans_Agy99           AQANAAAAVFEAAQAATAHPELVAANRNQLVSLVVSNLFGQNAPAIASTE
MAV_2910|M.avium_104                AQAKLAAAAYETAFAATVPPPVIAANRALLATLVATNILGQNTPAIAATE
Mflv_0325|M.gilvum_PYR-GCK          VQHDTAAAAYTTALATMPTLPELALNHTTHAVLVGTNFLGINTIPIALNE
Mvan_0415|M.vanbaalenii_PYR-1       AQHEAAAAAYSTALATMPTLPELALNHTTHAVLVATNFLGINTIPIAMTE
MSMEG_0619|M.smegmatis_MC2_155      VQHETAAAAYSTALATMPTMAELALNHTMHGVLVATNFFGINTIPIALNE
MAB_0047|M.abscessus_ATCC_1997      VLHETSAAAYTTALAAMPTLAELAANHMIHGVLLATNFFGINTIPIALNE
TH_3113|M.thermoresistible__bu      AQLEAAAAAHASALAAMPTMAELTANRTTHAALVATNFFGVNTIPIAVNE
MLBr_01182|M.leprae_Br4923          TQLTVAANAYETAFTMTVPPLMVFVNRAQACLLIMSNIFGQNSTAIAEKE
                                         :. .. :* :       :  *:     *: :*::* *: .**  *

Rv0305c|M.tuberculosis_H37Rv        AAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSERLTS---
Mb0313c|M.bovis_AF2122/97           AAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSERLTS---
MMAR_1639|M.marinum_M               AQYEQMWAQDVVAMLDYHAGASSVAAALTPLSWPTQTLAGLAAPAAALGS
MUL_0965|M.ulcerans_Agy99           AAYDQLWAQDVAAMAGYHSGASAVAAQLAPWQQALRTLQNRVAGATTALP
MAV_2910|M.avium_104                AHYMEMWAQDAAAMYAYAA-SSASAAQLTPFTEPPRTTNESAGPLQS---
Mflv_0325|M.gilvum_PYR-GCK          ADYVRMWIQAATTMATYQSVSGAALAATPTSAPAPSVLLPGVGEAGR---
Mvan_0415|M.vanbaalenii_PYR-1       ADYVRMWIQAATTMATYQAVSGAALAATPTATPAPFVLAPGVGEAGR---
MSMEG_0619|M.smegmatis_MC2_155      ADYVRMWIQAATTMSTYQAVSGAAVAAAPVSAPAPFLLKPGVGEAGS---
MAB_0047|M.abscessus_ATCC_1997      ADYIRMWIQAATTMGVYQGVSSAALAATTPTQPSPMIMAPG-GEMSR---
TH_3113|M.thermoresistible__bu      ADYARMWIQAATTMATYEAVASAAVSATPRTVAPPPILGAGTGESAT---
MLBr_01182|M.leprae_Br4923          AEYTEMWIQDAAAMTSYQASVLEAVGATKAFTAPPLGVNEVGLAQEVV--
                                    * * .:* * ..:*  * .      .                        

Rv0305c|M.tuberculosis_H37Rv        -------------AAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVG
Mb0313c|M.bovis_AF2122/97           -------------AAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVG
MMAR_1639|M.marinum_M               VARSISFNVGFANAGQGNVGAANIGDFNLGLGNIGSGNVGSGNIGGINVG
MUL_0965|M.ulcerans_Agy99           PPG--------PAAAAALPGAAAVGFPVLHIGNIGFANLSVGNIGDYNLG
MAV_2910|M.avium_104                -------------AAVAQSAAQSGSNTAAHLSQLSATAQPAAQA------
Mflv_0325|M.gilvum_PYR-GCK          -------------AAADMSAFAAQPMAAQAGAAFDVSNIIADIIRLYGEV
Mvan_0415|M.vanbaalenii_PYR-1       -------------AAADVTAFAAQAQAAEAGSALDLSNIIADLIRAYGEL
MSMEG_0619|M.smegmatis_MC2_155      -------------ASASVQQMSAQATAAESGSSLDLSSIISDLLNQYLQG
MAB_0047|M.abscessus_ATCC_1997      -------------MSADMMSMAAQPQAAESGSALDSSNNIMDQL------
TH_3113|M.thermoresistible__bu      -------------AAITGAHVTAELRAAESRTLLDEINELIDRLFAPLFP
MLBr_01182|M.leprae_Br4923          -------------EEVVEEVVEEVVEAEQAISQAALDQAVNEGMEATVVP
                                                                                      

Rv0305c|M.tuberculosis_H37Rv        FGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGSNNVGFG--------
Mb0313c|M.bovis_AF2122/97           FGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGSNNVGFG--------
MMAR_1639|M.marinum_M               SGNRGSYNIGPGNLGDYNIGLGNLGDSSVGFGNAGDHNVGVANAGFNNFG
MUL_0965|M.ulcerans_Agy99           SGNTGSFNLGSGNIGDASLGSGNAGDSNVGFGNFGSNNVGIG--------
MAV_2910|M.avium_104                AGNAASTTAASTQLTTPSFITN--------WNEFWSVVTGVY--------
Mflv_0325|M.gilvum_PYR-GCK          LRFLFEPIFNFLRDP---------------IGNTFALITDFL--------
Mvan_0415|M.vanbaalenii_PYR-1       LRFLFEPIFDFLRDP---------------LGNTIKLITDFL--------
MSMEG_0619|M.smegmatis_MC2_155      VPGG-QAILDFLKDP---------------LGNLGRLLTDFM--------
MAB_0047|M.abscessus_ATCC_1997      --------MRFMTNP---------------LGTLQDMIEDFM--------
TH_3113|M.thermoresistible__bu      PG----FADALPDGL---------------LGTLLAPLLPGA--------
MLBr_01182|M.leprae_Br4923          -----------------------------QVDQQVNVDVATP--------
                                                                                      

Rv0305c|M.tuberculosis_H37Rv        --NTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNS----
Mb0313c|M.bovis_AF2122/97           --NTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNS----
MMAR_1639|M.marinum_M               FANTGSNNIGIGLSGDGQVGIGALNSGTGNIGLFNSGTDNIGLFNSGTGN
MUL_0965|M.ulcerans_Agy99           --NNGNNNIGIGLNGDDLIGIGALNSGAGNLGFGNSGTNNIGFFNS----
MAV_2910|M.avium_104                -----SPQSWTTIPGGPFLSFG----------------------------
Mflv_0325|M.gilvum_PYR-GCK          -----TNPVQALITWGPFLLAVVYQA------------------------
Mvan_0415|M.vanbaalenii_PYR-1       -----TNPAQALITWGPFLAAVAYQA------------------------
MSMEG_0619|M.smegmatis_MC2_155      -----TNPAGALATWWPFLFGVAYQVFFN---------------------
MAB_0047|M.abscessus_ATCC_1997      -----RNPVAAFFAWFPLLFFIAYEAFFI---------------------
TH_3113|M.thermoresistible__bu      -----TGDGPPMATIMSFLLMGLSNP------------------------
MLBr_01182|M.leprae_Br4923          --QTAVPDSSSAAAPQLWG-------------------------------
                                                                                      

Rv0305c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb0313c|M.bovis_AF2122/97           --------------------------------------------------
MMAR_1639|M.marinum_M               FGIGNSGDYNTGIGNAGATNTGLLNAGLVNTGVGNAGNYNSGGFNAGHTN
MUL_0965|M.ulcerans_Agy99           --------------------------------------------------
MAV_2910|M.avium_104                --------------------------------------------------
Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0619|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0047|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Rv0305c|M.tuberculosis_H37Rv        ----------------GTGNFGIGN-------------------------
Mb0313c|M.bovis_AF2122/97           ----------------GTGNFGIGN-------------------------
MMAR_1639|M.marinum_M               TGSFNSGDYNTGYLNPGNYNTGLANSGDVNTGAFISGNYSNGAFWRGDHQ
MUL_0965|M.ulcerans_Agy99           ------GDNNIGFFNSGSGNFGFENAGDINTG-----------FWNGRDT
MAV_2910|M.avium_104                --------------------------------------------------
Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0619|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0047|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Rv0305c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb0313c|M.bovis_AF2122/97           --------------------------------------------------
MMAR_1639|M.marinum_M               GTGISYSVTIPAIPININETYSLDIPFTEDIGPRSIASFVIPRQSVTVIG
MUL_0965|M.ulcerans_Agy99           --------------------------------------------------
MAV_2910|M.avium_104                --------------------------------------------------
Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0619|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0047|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Rv0305c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb0313c|M.bovis_AF2122/97           --------------------------------------------------
MMAR_1639|M.marinum_M               IDLLYLGPITIPQINITGPVLSFEIGPATLRLHATGEIGPVEVPIIDIPA
MUL_0965|M.ulcerans_Agy99           --------------------------------------------------
MAV_2910|M.avium_104                --------------------------------------------------
Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0619|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0047|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Rv0305c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb0313c|M.bovis_AF2122/97           --------------------------------------------------
MMAR_1639|M.marinum_M               TPGFGNTTTNPSSGFFNTGDGSVSGFGNFAARTSGFLNVGSGSSGVQNLG
MUL_0965|M.ulcerans_Agy99           --------------------------------------------------
MAV_2910|M.avium_104                --------------------------------------------------
Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0619|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0047|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Rv0305c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb0313c|M.bovis_AF2122/97           --------------------------------------------------
MMAR_1639|M.marinum_M               ALQSGLANLGDTVSGAFNTGLGVPAHVSGVGNVGSELAGFFRDAAGQAPF
MUL_0965|M.ulcerans_Agy99           --------------------------------------------------
MAV_2910|M.avium_104                --------------------------------------------------
Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0619|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0047|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Rv0305c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb0313c|M.bovis_AF2122/97           --------------------------------------------------
MMAR_1639|M.marinum_M               NLGLGNIGFGNVGSANVGSFNVGPANMGDYNIGPGNLGNYNVGLGNLGDS
MUL_0965|M.ulcerans_Agy99           -----NTGFG----------------------------------------
MAV_2910|M.avium_104                --------------------------------------------------
Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0619|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0047|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Rv0305c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb0313c|M.bovis_AF2122/97           --------------------------------------------------
MMAR_1639|M.marinum_M               SVGLANAGDLNVGVANAGSNNFGLANTGSNNIGIGLSGDGQVGFGALNSG
MUL_0965|M.ulcerans_Agy99           --------------------------------------------------
MAV_2910|M.avium_104                --------------------------------------------------
Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0619|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0047|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Rv0305c|M.tuberculosis_H37Rv        ------------------SGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPG
Mb0313c|M.bovis_AF2122/97           ------------------SGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPG
MMAR_1639|M.marinum_M               TGNIGLFNSGADNIGLFNSGTGNFGIGNSGDYNTGIGNAGATNTGLLNAG
MUL_0965|M.ulcerans_Agy99           -----------------NSGLSNFGFGNSGVNNVGAGNGGSSNVGLGNAG
MAV_2910|M.avium_104                ---------------------QAYAWGQNGQGAAAYLAGPKAISGALAP-
Mflv_0325|M.gilvum_PYR-GCK          ------------------VSWVGASILYPSLFLLPLLATT--LAIVAGVG
Mvan_0415|M.vanbaalenii_PYR-1       ------------------VSWVGASILYPSLLLLPLVATT--LAIVLGVG
MSMEG_0619|M.smegmatis_MC2_155      -----------------LVGWPTWGMIFASPFLIPALAALGITGLVLLID
MAB_0047|M.abscessus_ATCC_1997      -----------------PFGFTFWGVLLSAPAWLPIVLGLALSALVPPAG
TH_3113|M.thermoresistible__bu      -----------------AYLFPVLVYLLFTGVVHTTVAVSGMLAQLVPLM
MLBr_01182|M.leprae_Br4923          ------------------------GFAQHLSPINDTLSMINNHAGMANAG
                                                                                      

Rv0305c|M.tuberculosis_H37Rv        SYNT----------GNFNTGNYNTGSFNAGNYNTGYFNTGDYNTGVANTG
Mb0313c|M.bovis_AF2122/97           SYNT----------GNFNTGNYNTGSFNAGNYNTGYFNTGDYNTGVANTG
MMAR_1639|M.marinum_M               LVNTGVSNAGNYNSGGFNAGHTNTGSFNSGDYNTGYLNPGNYNTGLVNSG
MUL_0965|M.ulcerans_Agy99           LLNT----------GSFNSGKFNTGDFNSGSMNTGYFNSSGHNTGLGNSG
MAV_2910|M.avium_104                ----------------LASGGNAVKPMLSSAVGAGQVSGSMGKAALVGS-
Mflv_0325|M.gilvum_PYR-GCK          QHLL----------SLLNTPPAEEAAEEPAPAQSAPSRPDQQSFPATMSA
Mvan_0415|M.vanbaalenii_PYR-1       AYLL----------ENLPAPAEDAPAEEPAASSPAPTRADQPSPAIAVSA
MSMEG_0619|M.smegmatis_MC2_155      HVLN----------NPVDVPAEDEAPQEVAAAP----RTDQP-LAVGISP
MAB_0047|M.abscessus_ATCC_1997      ---------------IEEPGQEDEPGREPTRIE---RRSPQQDLQLAHVP
TH_3113|M.thermoresistible__bu      PALL----------PVAVAALGGLAGVWAGLSGLAGLAGLTAVPAADGGA
MLBr_01182|M.leprae_Br4923          LSLVN----------GMGSAMKSLAPTTTKAAES---AFKAMGSAVQSTG
                                                                                      

Rv0305c|M.tuberculosis_H37Rv        NVNTGAFIAGNYSNGVLWRGDYQGLIG-----------------------
Mb0313c|M.bovis_AF2122/97           NVNTGAFIAGNYSNGVLWRGDYQGLIG-----------------------
MMAR_1639|M.marinum_M               DVNTGAFISGDYSNGAFWRGDHQGLADISYGITIPEIPAHIEGTIPLAVP
MUL_0965|M.ulcerans_Agy99           FTNTGFFNSGD---------------------------------------
MAV_2910|M.avium_104                --------------------------------------------------
Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0619|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0047|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Rv0305c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb0313c|M.bovis_AF2122/97           --------------------------------------------------
MMAR_1639|M.marinum_M               VTMTSTNTVIHAVTIPVFDAGFLGIPIDAGPVTIPAIVITGPTLTGIIGG
MUL_0965|M.ulcerans_Agy99           --------------------------------------------------
MAV_2910|M.avium_104                --------------------------------------------------
Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0619|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0047|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Rv0305c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb0313c|M.bovis_AF2122/97           --------------------------------------------------
MMAR_1639|M.marinum_M               PTSAININTGQHVGPIRLSFLDIPAAPGFGNSTTNPSSGFFNLGQGTVSG
MUL_0965|M.ulcerans_Agy99           --------------------------------------------------
MAV_2910|M.avium_104                --------------------------------------------------
Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0619|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0047|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Rv0305c|M.tuberculosis_H37Rv        -----------------------------------------ADIALEIPA
Mb0313c|M.bovis_AF2122/97           -----------------------------------------ADIALEIPA
MMAR_1639|M.marinum_M               FGNLGARTSGFLNVGSGISGVQNVGALQSGLANLGDTVSGAFNTGLGVPA
MUL_0965|M.ulcerans_Agy99           -----------------------------------------LNTGMGSPE
MAV_2910|M.avium_104                ---------------------------------------------MSVPQ
Mflv_0325|M.gilvum_PYR-GCK          ---------------------------------------------PPPPS
Mvan_0415|M.vanbaalenii_PYR-1       ---------------------------------------------PPPPS
MSMEG_0619|M.smegmatis_MC2_155      ---------------------------------------------AGVPG
MAB_0047|M.abscessus_ATCC_1997      ---------------------------------------------SGSPT
TH_3113|M.thermoresistible__bu      ---------------------------------------------SAAPV
MLBr_01182|M.leprae_Br4923          ---------------------------------------------RGLLG
                                                                                      

Rv0305c|M.tuberculosis_H37Rv        IPIN----------------------------------------------
Mb0313c|M.bovis_AF2122/97           IPIN----------------------------------------------
MMAR_1639|M.marinum_M               HVSGLGNAGSELAGFFRDATGHARFNLGLGNIGSGNVGSGNIGGANVGSG
MUL_0965|M.ulcerans_Agy99           DQS-----------------------------------------------
MAV_2910|M.avium_104                G-------------------------------------------------
Mflv_0325|M.gilvum_PYR-GCK          GAPI----------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       SAAA----------------------------------------------
MSMEG_0619|M.smegmatis_MC2_155      SAAT----------------------------------------------
MAB_0047|M.abscessus_ATCC_1997      PGGS----------------------------------------------
TH_3113|M.thermoresistible__bu      PAGG----------------------------------------------
MLBr_01182|M.leprae_Br4923          SSSG----------------------------------------------
                                                                                      

Rv0305c|M.tuberculosis_H37Rv        ------------------------------------AQLFSMPIHQVMVM
Mb0313c|M.bovis_AF2122/97           ------------------------------------AQLFSMPIHQVMVM
MMAR_1639|M.marinum_M               NIGDYNIGPANLGDYNIGLGNLGDSSIGLANAGDHNLGVANAGFNNFGFA
MUL_0965|M.ulcerans_Agy99           --------------------------------------VANSGFRNAGSG
MAV_2910|M.avium_104                --------------------------------------------------
Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0619|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0047|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Rv0305c|M.tuberculosis_H37Rv        PGSVMTIP------------GMRLPFTSIVPFVVYYGPVELPQSTLTLPT
Mb0313c|M.bovis_AF2122/97           PGSVMTIP------------GMRLPFTSIVPFVVYYGPVELPQSTLTLPT
MMAR_1639|M.marinum_M               NTGNNNIGIGLSGDGQVGFGALNSGTGNIGLFNSGTDNIGLFNSG-TGNF
MUL_0965|M.ulcerans_Agy99           NSGFN-----------------NTGSFSSGFFNSTNSNSEFLNAGGTVNS
MAV_2910|M.avium_104                --------------------------------------------------
Mflv_0325|M.gilvum_PYR-GCK          ------------------------------------------------AA
Mvan_0415|M.vanbaalenii_PYR-1       ------------------------------------------------TV
MSMEG_0619|M.smegmatis_MC2_155      ------------------------------------------------AA
MAB_0047|M.abscessus_ATCC_1997      ------------------------------------------------TT
TH_3113|M.thermoresistible__bu      ------------------------------------------------PS
MLBr_01182|M.leprae_Br4923          ------------------------------------------------GH
                                                                                      

Rv0305c|M.tuberculosis_H37Rv        VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPG---------------
Mb0313c|M.bovis_AF2122/97           VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPG---------------
MMAR_1639|M.marinum_M               GIGNSGDYNTGIGNAGATNTGLLNAGLVNTGVGNAGNYNSGGFNTGSTNT
MUL_0965|M.ulcerans_Agy99           GINNSGNTNAGIGNLGDDNFGLFNNGTFNTGAGNS----SG---------
MAV_2910|M.avium_104                -WTEAAPAIRTLAQVLPGNMAAAPAAMAGE--------------------
Mflv_0325|M.gilvum_PYR-GCK          NTVSAG-SPPAPGAPAAAAATFVPYVVAGRDPYEG---------------
Mvan_0415|M.vanbaalenii_PYR-1       GTVATG-TAPAPGAPAAATASFVPYAVAGRDPGTG---------------
MSMEG_0619|M.smegmatis_MC2_155      APAPAP-AGTTVAAPAPAAATFVPYAVANRDPGEG---------------
MAB_0047|M.abscessus_ATCC_1997      TTVTSGGSAPPAPAPATATPAYMVYAVQEDPPAAR---------------
TH_3113|M.thermoresistible__bu      LPSGSSAPPAPTGSAAPTTGTAPGGAGSPPPAGHS---------------
MLBr_01182|M.leprae_Br4923          VTAQLGRAASIGSLRVPQTWTTASQPVTAATRALS---------------
                                                                                      

Rv0305c|M.tuberculosis_H37Rv        -------FGNSTTSP---SSGFFNAGAGTASGFGNFGGG-----------
Mb0313c|M.bovis_AF2122/97           -------FGNSTTSP---SSGFFNAGAGTASGFGNFGGG-----------
MMAR_1639|M.marinum_M               GSFNSGDYNTGYLNPGNYNTGLANSGDVNTGAFISGDYSNGAFWRGDHQG
MUL_0965|M.ulcerans_Agy99           ----------GAVFP--YTSGLFNSGNGSSGVFNAGDEQ-----------
MAV_2910|M.avium_104                --------------------------------------------------
Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0619|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0047|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Rv0305c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb0313c|M.bovis_AF2122/97           --------------------------------------------------
MMAR_1639|M.marinum_M               LVGFSYAINIPETPGHAEISIPIDIPINGTIGDINTPRVRIPEFPLNVYV
MUL_0965|M.ulcerans_Agy99           --------------------------------------------------
MAV_2910|M.avium_104                --------------------------------------------------
Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0619|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0047|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Rv0305c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb0313c|M.bovis_AF2122/97           --------------------------------------------------
MMAR_1639|M.marinum_M               FTPIHVGDVGPIVLPPIRITGPTLTGNIGGPTTSIDIGIGGTLGPAKITI
MUL_0965|M.ulcerans_Agy99           --------------------------------------------------
MAV_2910|M.avium_104                --------------------------------------------------
Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0619|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0047|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Rv0305c|M.tuberculosis_H37Rv        ----------------ASGFWNLASATSG--------LSGFGNVGALGSG
Mb0313c|M.bovis_AF2122/97           ----------------ASGFWNLASATSG--------LSGFGNVGALGSG
MMAR_1639|M.marinum_M               IDIPAAPGFGNSTTSPSSGFFNSGDGSVSGFGNFGDHTSGLVNFGSGNSG
MUL_0965|M.ulcerans_Agy99           -----------------SGFFG---------------TSGLVLTGTDGLA
MAV_2910|M.avium_104                ------------------------------------------------EG
Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0619|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0047|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Rv0305c|M.tuberculosis_H37Rv        VANVGNTISGLYN-------TSTSNLATPAFNSGLLHHS----------V
Mb0313c|M.bovis_AF2122/97           VANVGNTISGLYN-------TSTSNLATPAFNSGLLHHS----------V
MMAR_1639|M.marinum_M               AQNVGALQSGLANLGDTVSGAFNTGLGVPAHVSGVGNVGSELAGFFRDAT
MUL_0965|M.ulcerans_Agy99           ATTT----SGLP------------ALDLPAPNLGIGNAG----------V
MAV_2910|M.avium_104                VF-S----------------------------------------------
Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0619|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0047|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Rv0305c|M.tuberculosis_H37Rv        GTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFA
Mb0313c|M.bovis_AF2122/97           GTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFA
MMAR_1639|M.marinum_M               GHAPFNLGLGNIGFGNVGSANAGNFNVGSANIGDYNIGPGNLGDYNIGLG
MUL_0965|M.ulcerans_Agy99           G----NLGLGNIGDYNLGSGNTGDANFGSGNIGALNLGSGNHGDANLGFG
MAV_2910|M.avium_104                -----QMALSSLAGRAVAAAAT-------RPVGGAASAASSLGGVAAEAD
Mflv_0325|M.gilvum_PYR-GCK          ------FSPTVRDSTGAKAPAGTIPAAASGIAASAAERRKRRRRQKEEIK
Mvan_0415|M.vanbaalenii_PYR-1       ------FSPTVRDSTSAKAPASGIPAAASGVAASAAERRKRRRRQKDEIA
MSMEG_0619|M.smegmatis_MC2_155      ------FTPTLGNKSQVAAPASGVPAAASGVAASLASRRKRRRKKGAQIE
MAB_0047|M.abscessus_ATCC_1997      ------FGPTLNEGSGAKAPAAGISAAAA-AAASARSRARRKRAARIKDP
TH_3113|M.thermoresistible__bu      ------VPPAPHSAPPVGTSGPPYLIAAQPAPGVARRSAGARRAASIVEP
MLBr_01182|M.leprae_Br4923          ---------PARVAVATESESAPLLGGGLPMAPMVPGGGSGTGGVNTALR
                                                                                      

Rv0305c|M.tuberculosis_H37Rv        HAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFG
Mb0313c|M.bovis_AF2122/97           HAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFG
MMAR_1639|M.marinum_M               NLGDSSIGLANAGDHNLGVANAGFNNFGFANTGNNNIGIGLSGDGQVGIG
MUL_0965|M.ulcerans_Agy99           NTGDNNIGLFNSGDNNVGFFNSGGANFGLANSGDTNT-------------
MAV_2910|M.avium_104                PAAATIIVIPCIEE------------------------------------
Mflv_0325|M.gilvum_PYR-GCK          GRGYADAYADYEELPDDGPPEQPAPRVTAST-------------------
Mvan_0415|M.vanbaalenii_PYR-1       GRAYADAYADYEPEPDDEPPVRQEPRIAATE-------------------
MSMEG_0619|M.smegmatis_MC2_155      ERGYADAYMDYEE-PDEDPAPQPEPRVRASE-------------------
MAB_0047|M.abscessus_ATCC_1997      APQFMDMNSSVAPDFSES-AARQTTGVGASA-------------------
TH_3113|M.thermoresistible__bu      AGSAAAAAAARESAPIRRRRGQKDGLHGHRH-------------------
MLBr_01182|M.leprae_Br4923          LQPRAFVMPRNPAAG-----------------------------------
                                                                                      

Rv0305c|M.tuberculosis_H37Rv        SLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFG
Mb0313c|M.bovis_AF2122/97           SLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFG
MMAR_1639|M.marinum_M               ALNSGTGNIGLFNSGTDNIGLFNSGTGNFGIGNSGDYNTGIGNAGATNTG
MUL_0965|M.ulcerans_Agy99           ---------GLWNAGSTNTGFGNAGSADFGFGNAGDRNMGFGNAGAAN--
MAV_2910|M.avium_104                --------------------------------------------------
Mflv_0325|M.gilvum_PYR-GCK          -------------RGAGPMGFAGTVSRGD--EQAGGLT------------
Mvan_0415|M.vanbaalenii_PYR-1       -------------RGAGPMGFAGTVSRDA--AQAGGLT------------
MSMEG_0619|M.smegmatis_MC2_155      -------------RGSDAMGFTGTVTRHD--VTAAGLT------------
MAB_0047|M.abscessus_ATCC_1997      -------------RGAGRLGFAGTAPAAAGTTAAAGLVERD---------
TH_3113|M.thermoresistible__bu      -------------EHQQPASMSAATAPSAAGIRVLGGAG-----------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Rv0305c|M.tuberculosis_H37Rv        IGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTG
Mb0313c|M.bovis_AF2122/97           IGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTG
MMAR_1639|M.marinum_M               LLNAGLVNTGVGNAGNYNSGGLNAGHTNTGSFNSGDYNTGYLNPGNYNTG
MUL_0965|M.ulcerans_Agy99           --------MGAGNSGSYNTGSFNSGTLNTGDFNGGDHNTGWGNSGNTNTG
MAV_2910|M.avium_104                --------------------------------------------------
Mflv_0325|M.gilvum_PYR-GCK          -------TLAGDSFGGGPREPMLPGTWDPDATDDRHTDGRDGHDGHDGKE
Mvan_0415|M.vanbaalenii_PYR-1       -------TLPGDPFGGGPKAPMLPGTWDPDTEPD------ERHNHHDGKD
MSMEG_0619|M.smegmatis_MC2_155      -------TLTGDTFDDRPVTPMLPGTWDGDENPAP------SPDDPEGGP
MAB_0047|M.abscessus_ATCC_1997      -------SGTAEALDGARTVPMLPTSWGTDSEHGP-------DRPAEGGS
TH_3113|M.thermoresistible__bu      --------RISRTRGSVPHAEITPGDPTEPSSPTDR-----AHRPAEPN-
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Rv0305c|M.tuberculosis_H37Rv        YFNTGDLQH-------------RHGEHR----------------------
Mb0313c|M.bovis_AF2122/97           YFNTGDYNTGMANTGNINTGAFISGNHSNGLLWRGDNQGLIDLAIGVDIP
MMAR_1639|M.marinum_M               MVNSGDVNTGAFISGDYSNGAFWRGDHQGLVGFSYGFTIPALPAQ-----
MUL_0965|M.ulcerans_Agy99           GINSGDLNTG----------------------------------------
MAV_2910|M.avium_104                --------------------------------------------------
Mflv_0325|M.gilvum_PYR-GCK          KP------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       SQ------------------------------------------------
MSMEG_0619|M.smegmatis_MC2_155      RR------------------------------------------------
MAB_0047|M.abscessus_ATCC_1997      ST------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Rv0305c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb0313c|M.bovis_AF2122/97           EIPIVSVDVNIPIHIPITASFTDIVYSGLDLPPNTAVTVIFFGPVDIDPF
MMAR_1639|M.marinum_M               ----LEAQIPVNIPATATAGDTTIHSATFPAIHFDTFGLLPQSNGTFGPV
MUL_0965|M.ulcerans_Agy99           --------------------------------------------------
MAV_2910|M.avium_104                --------------------------------------------------
Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0619|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0047|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Rv0305c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb0313c|M.bovis_AF2122/97           TVPVIRITGPTPVVMVGGPTTAINIGATVGVDAINIPIIHIPATPGFGNS
MMAR_1639|M.marinum_M               TLPDITLSGPTFSLLMGGPDTVVGIKAGGVAGPVTFSFIDIPAAPGFGNT
MUL_0965|M.ulcerans_Agy99           --------------------------------------------------
MAV_2910|M.avium_104                --------------------------------------------------
Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0619|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0047|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Rv0305c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb0313c|M.bovis_AF2122/97           TGGLSSGFFNSGAGSASGFGNFGGAASGFMNLVSTTSGMSGFLNVGALGS
MMAR_1639|M.marinum_M               TATPSSGFFNSGAGSASGFGNSGADNSGLLNL---AFGSSGYQNVGALQS
MUL_0965|M.ulcerans_Agy99           ------------------FGSS----------------------------
MAV_2910|M.avium_104                --------------------------------------------------
Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0619|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0047|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Rv0305c|M.tuberculosis_H37Rv        -----------QYQHR---------------------RFHLRQPQQRPSV
Mb0313c|M.bovis_AF2122/97           GVANVGNTISGIYNVG---------------------TSDLSTPAVNSGL
MMAR_1639|M.marinum_M               GIANLGNTMSGVYNTGLAVPAHVSGIGNIGHNLAGLLRGTAGQVPVNVGF
MUL_0965|M.ulcerans_Agy99           ----------------------------------------ADQAVTNSGF
MAV_2910|M.avium_104                --------------------------------------------------
Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0619|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0047|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Rv0305c|M.tuberculosis_H37Rv        AGR-----------------------------------------------
Mb0313c|M.bovis_AF2122/97           ANIGTNIAGLLRDGAGTAAINLGLANHGNLNVGFASLGGFNFGGATIGHN
MMAR_1639|M.marinum_M               ANNGAG--------------------------------------------
MUL_0965|M.ulcerans_Agy99           GNNGSG--------------------------------------------
MAV_2910|M.avium_104                --------------------------------------------------
Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0619|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0047|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Rv0305c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb0313c|M.bovis_AF2122/97           NVGIGNTGIFDVGLANLGSYNIGFGNLGDDNLGFGNFGSYNIGFGNVGND
MMAR_1639|M.marinum_M               NVGFGNVGFSNVGSGNIGSFNVGSGNIGDYNIGPGNLGDYNIGLGNLGDS
MUL_0965|M.ulcerans_Agy99           NSGFNNTGDTNSGFHNANTSALFSGHSGLLNAG--------------GSQ
MAV_2910|M.avium_104                --------------------------------------------------
Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0619|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0047|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Rv0305c|M.tuberculosis_H37Rv        ---------------QPGSDRPRHRRRHSR--------------------
Mb0313c|M.bovis_AF2122/97           NLGFANAGGGNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSG
MMAR_1639|M.marinum_M               SIGFGNAGDHNVGVANAGFNNFGFANTGSNNIGIGLNGDGQVGFGALNSG
MUL_0965|M.ulcerans_Agy99           SVGINNTGSFNTVLFNTGFRTAGIANSATN--------------------
MAV_2910|M.avium_104                --------------------------------------------------
Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0619|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0047|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Rv0305c|M.tuberculosis_H37Rv        -------NPDCERRREYPDSH--------------------TDHRQLHGH
Mb0313c|M.bovis_AF2122/97           SGNIGLFNSGSNNIGFFNSGS--------------------GNFGIANSG
MMAR_1639|M.marinum_M               TGNIGLFNSGTDNIGLFNSGTGNFGIGNSGDYNTGIGNAGATNTGLLNAG
MUL_0965|M.ulcerans_Agy99           --------------------------------------------GLLTA-
MAV_2910|M.avium_104                --------------------------------------------------
Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0619|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0047|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Rv0305c|M.tuberculosis_H37Rv        RIQRARSSTEHSRHCYF------------------------FRTRRYRP-
Mb0313c|M.bovis_AF2122/97           SFNTGIGNTGNTNTGLFNSGDVNTGAFNPGSFNTGSFNTGSFNTGGFNPG
MMAR_1639|M.marinum_M               LVNTGVGNAGNYNSGGFN--------------------TGSTNTGSFNPG
MUL_0965|M.ulcerans_Agy99           --TSGVANSGNNSSGGFN--------------------ANPDQSGFFN--
MAV_2910|M.avium_104                --------------------------------------------------
Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0619|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0047|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Rv0305c|M.tuberculosis_H37Rv        -------------------------LHRPSDTDNRSHTCG-HGGWTHYRD
Mb0313c|M.bovis_AF2122/97           NTNTG----------YLNIGNYNTGIANTGDVDTGAFITGNYSNGLFLSG
MMAR_1639|M.marinum_M               DYNTGGLNQGDYNTGYLNSGDYNTGFVNAGDVNTGAFISGNYSNGFFARG
MUL_0965|M.ulcerans_Agy99           --------------------------------------------------
MAV_2910|M.avium_104                --------------------------------------------------
Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0619|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0047|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Rv0305c|M.tuberculosis_H37Rv        QYR-----------------------------RHCGRRRHQHPDYPYSSD
Mb0313c|M.bovis_AF2122/97           DYQGLVGLNLVIDMPLPISL-GVNIPIDIPITASAGNITLMGVTIPPTGD
MMAR_1639|M.marinum_M               DYQNLIGWSYSITVSEFPAYGTLDIPVYIPFTGAIGPITIQEFTIPSLPL
MUL_0965|M.ulcerans_Agy99           --------------------------------------------------
MAV_2910|M.avium_104                --------------------------------------------------
Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0619|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0047|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Rv0305c|M.tuberculosis_H37Rv        SRLRQLDRR------------TVVGLLQ----------------------
Mb0313c|M.bovis_AF2122/97           IVLSSIAGQRAHFGPITIPNITVVGPTTTVAIGGPNTAITITGGG-----
MMAR_1639|M.marinum_M               DALVYINGTPIPIFYDFGPITVDETTTDPIALNFVWDQLYHYEVGPRTFG
MUL_0965|M.ulcerans_Agy99           --------------------------------------------------
MAV_2910|M.avium_104                --------------------------------------------------
Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0619|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0047|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Rv0305c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb0313c|M.bovis_AF2122/97           ----------AIRIPLISIPAAPGFGNSTTNPSSGFFNTGAGGASGFGNF
MMAR_1639|M.marinum_M               PYEIPLFSFPGPGFANSTTSPSSGFFNSGTGPTSGFFNSGAGSLSGLINL
MUL_0965|M.ulcerans_Agy99           --------------------------------------------------
MAV_2910|M.avium_104                --------------------------------------------------
Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0619|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0047|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Rv0305c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb0313c|M.bovis_AF2122/97           GGANSGFWNLASATSGASGLLNVGALGSGLANVGTTVSGFYNTSTSDLAT
MMAR_1639|M.marinum_M               GANNSGFANTGIGGLGNSGFINDGALQSGMANVGNTISGIYNSTTLDPTA
MUL_0965|M.ulcerans_Agy99           --------------------------------------------------
MAV_2910|M.avium_104                --------------------------------------------------
Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0619|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0047|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Rv0305c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb0313c|M.bovis_AF2122/97           PAFNSGLANISTSIAGLLRDSTGTMVLNLGLANHGTLNVGIANLGDYNIG
MMAR_1639|M.marinum_M               VANVSGIANTGVDLAGVFRGAS--RIHNLGFANLGIANLGSANIGDLNLG
MUL_0965|M.ulcerans_Agy99           --------------------------------------------------
MAV_2910|M.avium_104                --------------------------------------------------
Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0619|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0047|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Rv0305c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb0313c|M.bovis_AF2122/97           FANLGSANFGSANIGGNNIGGANTGIFDIGLANLGSYNIGFGNFGDDNLG
MMAR_1639|M.marinum_M               GANFGSANIGSGNIGFGNVGGGNVGSLNLGFGNLGDHNIGPGNLGDYNIG
MUL_0965|M.ulcerans_Agy99           --------------------------------------------------
MAV_2910|M.avium_104                --------------------------------------------------
Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0619|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0047|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Rv0305c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb0313c|M.bovis_AF2122/97           FGNLGSYNVGFGNLGNDNLGFANTGSNNIGFANTGSNNIGIGLTGDGQIG
MMAR_1639|M.marinum_M               LGNLGDSNVGFGNAGDHNVGVGNAGFNNFGFANTGSNNIGIGLSGDGQVG
MUL_0965|M.ulcerans_Agy99           --------------------------------------------------
MAV_2910|M.avium_104                --------------------------------------------------
Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0619|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0047|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Rv0305c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb0313c|M.bovis_AF2122/97           FGSLNSGSGNIGLFNSGSGNIGFFNSGNGNVGIGNTGTANFGLGNTGSTN
MMAR_1639|M.marinum_M               FGALNSGTGNIGLFNSGTDNIGLFNSGTGNIGLFNSGTGSFGIGNSGNYN
MUL_0965|M.ulcerans_Agy99           --------------------------------------------------
MAV_2910|M.avium_104                --------------------------------------------------
Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0619|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0047|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Rv0305c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb0313c|M.bovis_AF2122/97           TGFFNSGDVNTGIGNTGSFNTGSFNPGDSNTGDFNPGSYNTGLGNTGDVD
MMAR_1639|M.marinum_M               TGIGNAGATNTGLFNTGLVNTGVGNAGNYNSGGFNTGSTNTGSFNSGDHN
MUL_0965|M.ulcerans_Agy99           --------------------------------------------------
MAV_2910|M.avium_104                --------------------------------------------------
Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0619|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0047|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Rv0305c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb0313c|M.bovis_AF2122/97           TGAFISGSYSNGFLWSGNYQGLIGLHAALAIPEIALTFGVDIPIHIPINI
MMAR_1639|M.marinum_M               TGYLNSGDYNTGLANSGDVN-----TGAFISGNYSNGFFVDGDHQGLIDG
MUL_0965|M.ulcerans_Agy99           --------------------------------------------------
MAV_2910|M.avium_104                --------------------------------------------------
Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0619|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0047|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Rv0305c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb0313c|M.bovis_AF2122/97           DAGVVTLQGFSIVAAENNIDFTPIIIPTINITLPTAAITVGGPTTSIGIT
MMAR_1639|M.marinum_M               TPGFFNST------------------------------------------
MUL_0965|M.ulcerans_Agy99           --------------------------------------------------
MAV_2910|M.avium_104                --------------------------------------------------
Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0619|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0047|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Rv0305c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb0313c|M.bovis_AF2122/97           ASAGIGSITIPIIDIPATSGFGNSTTSPSSGFFNSGAGSASGFLNVVAGA
MMAR_1639|M.marinum_M               --------------TNPSSGLLNSGEGSESGVGNYGVGNSGFLNFASVTG
MUL_0965|M.ulcerans_Agy99           --------------------------------------------------
MAV_2910|M.avium_104                --------------------------------------------------
Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0619|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0047|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Rv0305c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb0313c|M.bovis_AF2122/97           SGISGYLNVGALGSGVTNVGHTVSGFYNASALDLVTPAFASGLMRDGMGT
MMAR_1639|M.marinum_M               AGSSGLLNVGALQSGILNLGSTISGFG---NTGSVTPAFVSGVANAGTRL
MUL_0965|M.ulcerans_Agy99           --------------------------------------------------
MAV_2910|M.avium_104                --------------------------------------------------
Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0619|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0047|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3113|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Rv0305c|M.tuberculosis_H37Rv        -------------------------------------------------
Mb0313c|M.bovis_AF2122/97           MTLNLGLANLGSNNAGFGNTGIFDVGVANLGNYNIGFGNFGDDNLALPT
MMAR_1639|M.marinum_M               SGFFFRGTGP---------------------------------------
MUL_0965|M.ulcerans_Agy99           -------------------------------------------------
MAV_2910|M.avium_104                -------------------------------------------------
Mflv_0325|M.gilvum_PYR-GCK          -------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       -------------------------------------------------
MSMEG_0619|M.smegmatis_MC2_155      -------------------------------------------------
MAB_0047|M.abscessus_ATCC_1997      -------------------------------------------------
TH_3113|M.thermoresistible__bu      -------------------------------------------------
MLBr_01182|M.leprae_Br4923          -------------------------------------------------