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NLVSTTSGMSGFLNVGALGSGVANVGNTISGIYNVGTSDLSTPAVNSGLANIGTNIAGLLRDGAGTAAIN LGLANHGNLNVGFASLGGFNFGGATIGHNNVGIGNTGIFDVGLANLGSYNIGFGNLGDDNLGFGNFGSYN IGFGNVGNDNLGFANAGGGNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSGNIGLFNSGS NNIGFFNSGSGNFGIANSGSFNTGIGNTGNTNTGLFNSGDVNTGAFNPGSFNTGSFNTGSFNTGGFNPGN TNTGYLNIGNYNTGIANTGDVDTGAFITGNYSNGLFLSGDYQGLVGLNLVIDMPLPISLGVNIPIDIPIT ASAGNITLMGVTIPPTGDIVLSSIAGQRAHFGPITIPNITVVGPTTTVAIGGPNTAITITGGGAIRIPLI SIPAAPGFGNSTTNPSSGFFNTGAGGASGFGNFGGANSGFWNLASATSGASGLLNVGALGSGLANVGTTV SGFYNTSTSDLATPAFNSGLANISTSIAGLLRDSTGTMVLNLGLANHGTLNVGIANLGDYNIGFANLGSA NFGSANIGGNNIGGANTGIFDIGLANLGSYNIGFGNFGDDNLGFGNLGSYNVGFGNLGNDNLGFANTGSN NIGFANTGSNNIGIGLTGDGQIGFGSLNSGSGNIGLFNSGSGNIGFFNSGNGNVGIGNTGTANFGLGNTG STNTGFFNSGDVNTGIGNTGSFNTGSFNPGDSNTGDFNPGSYNTGLGNTGDVDTGAFISGSYSNGFLWSG NYQGLIGLHAALAIPEIALTFGVDIPIHIPINIDAGVVTLQGFSIVAAENNIDFTPIIIPTINITLPTAA ITVGGPTTSIGITASAGIGSITIPIIDIPATSGFGNSTTSPSSGFFNSGAGSASGFLNVVAGASGISGYL NVGALGSGVTNVGHTVSGFYNASALDLVTPAFASGLMRDGMGTMTLNLGLANLGSNNAGFGNTGIFDVGV ANLGNYNIGFGNFGDDNLGFANLGSYNIGVANTGSNNIGFANTGSNNIGIGLTGTGQIGIGALNSGSGNI GLFNSGDGNIGFFNSGTGNFGIGNTGTGNFGIGNSGSTSTGLFNSGDGNTGGFNPGNFNTGNFNTGSFNT GGFNAGNTNTGHFNTGNYNTGIANTGDVSTGAFISGNYSNGILWRGDYQGLIGYSYALTIPEIPAHLDVN IPIDIPITGSFTDLVVDNFTIPIIGFESFAFSFHIHTEPDIGPIIVPSFVLSVPTFAIAVGGPTTAINIS ATAGLGPITIPIIDIPAAPGIGNSTTSPSSGFFNTGAGTASGFGNVGGNTSGLWNLASAASGVSGLLNVG ALGSGVANVGNTISGIYNTSPLDLGTPAFGSGLANIAGLLQGGAGTTILDLAGLGNLNVGLANLGGSNFG IGNTGIFNVGFANVGNHNIGLANLGNYSVGFANSGNYHIGIANTGSANIGFANTGSGNIGIGLTGTGQIG FGSFNSGSHNIGLFNSGDGNVGFFNSGTGNVGIGNTGTANFGIANSGSFNTGLGNTGSTNTGLFNPGNVN TGVGNTGSINTGSINTGSFNTGSTNTGSFNLGDHNTGSFNSGDYNTGYFNAGDYNTGVANTGNVNTGAFI SGNYSNGFFWRGDYQGLIGLSTTITIPEIPYRYDLSVPIDIPITGTVVATTPNSFTIPGFQIRVLLGPAA VLVNEMIGPITIDVNQVIAIDSPIQQTISMVGTGGFGPIPIGISIGGTPGFGNSTTGPSSGFFHTGAGHV SGFGNFGAGNMSGSGNFGAGNSGFFNAGGLGNSGLLNFGALQSGLANLGNTISGVYNTSTLDLATPAFGS GIANIGANLAGLFLDNTGNLTLNFGVANQGGLNAGIGNLGSVNIGFVNTGDSNLGIGNLGDLNFGGVNIG GNNIGIANTGIFDIGLANLGSYNIGLANLGDDNLGFGNAGSYNIGFANFGSDNLGFANTGSYNIGFANTG NNNIGVGLTGNGQIGIGSLNSGSNNIGLFNSGSGNIGFFNSGTGNVGIFNTGTGNFGLANSGGFNTGIGN AGSTNTGVFNPGDLNTGSFNPGSFNTGGFNPGSGNTGYLNTGDYNTGVANTGDVDTGAFITGSYSNGFLV SGDYQGLIGLPLLGIPVTPGYFNLTGGPSSGFFNSGAGSVSGFVNSGAGLSGYLNTGALGSGVANVGNTI SGWLNASALDLATPGFLSGIGNFGTNLAGFFRG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0304c | PPE5 | - | 100% (2204) | PPE FAMILY PROTEIN |
| M. tuberculosis H37Rv | Rv0355c | PPE8 | 0.0 | 48.76% (2375) | PPE family protein |
| M. tuberculosis H37Rv | Rv3350c | PPE56 | 0.0 | 37.09% (2804) | PPE family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0312c | PPE5 | 0.0 | 99.31% (1152) | PPE family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 1e-17 | 24.03% (932) | triple helix repeat-containing collagen |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4284c | - | 2e-17 | 24.48% (576) | hypothetical protein MAB_4284c |
| M. marinum M | MMAR_1639 | - | 0.0 | 54.49% (2292) | PPE family protein |
| M. avium 104 | MAV_0207 | - | 2e-06 | 26.09% (230) | Erp protein |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 1e-36 | 26.07% (1189) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 1e-07 | 28.15% (302) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_0965 | - | 1e-126 | 39.89% (732) | PPE family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 6e-18 | 27.59% (569) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv0304c|M.tuberculosis_H37Rv ------------------------------------------MNLVSTTS
Mb0312c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1639|M.marinum_M MNFAVLPPEINSARLFSGAGSGPVLAAATAWTGLAAELRSAAAAFLAVTS
MUL_0965|M.ulcerans_Agy99 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_0207|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv0304c|M.tuberculosis_H37Rv GMSG---------------------FLNVGALGSGVANVGNTISGIYNVG
Mb0312c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1639|M.marinum_M GLTGNSWRGPAAAVMSDVAASYVGWLSASGAHAEQAAEQAKTAAQVFEAA
MUL_0965|M.ulcerans_Agy99 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_0207|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv0304c|M.tuberculosis_H37Rv TSDLSTPAVNSG-----LANIGTNIAGL----------------------
Mb0312c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1639|M.marinum_M RAVTVQPGLVAANRAQLVSLVGSNLFGQNAPAIATAEAQYEQMWAQDVVA
MUL_0965|M.ulcerans_Agy99 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_0207|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv0304c|M.tuberculosis_H37Rv ------------------------LRDGAGTAAINLGLANHGNLNVGFAS
Mb0312c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1639|M.marinum_M MLDYHAGASSVAAALTPLSWPTQTLAGLAAPAAALGSVARSISFNVGFAN
MUL_0965|M.ulcerans_Agy99 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_0207|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv0304c|M.tuberculosis_H37Rv LGGFNFGGATIGHNNVGIGNTGIFDVGLANLGSYNIGFGNLGDDNLGFGN
Mb0312c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1639|M.marinum_M AGQGNVGAANIGDFNLGLGNIGSGNVGSGNIGGINVGSGNRGSYNIGPGN
MUL_0965|M.ulcerans_Agy99 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_0207|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv0304c|M.tuberculosis_H37Rv FGSYNIGFGNVGNDNLGFANAGGGNIGFANTGSNNVGFGNTGSNNVGIGL
Mb0312c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1639|M.marinum_M LGDYNIGLGNLGDSSVGFGNAGDHNVGVANAGFNNFGFANTGSNNIGIGL
MUL_0965|M.ulcerans_Agy99 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_0207|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv0304c|M.tuberculosis_H37Rv TGNGQIGFGSFNSGSGNIGLFNSGSNNIGFFNSGSGNFGIANSGSFNTGI
Mb0312c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1639|M.marinum_M SGDGQVGIGALNSGTGNIGLFNSGTDNIGLFNSGTGNFGIGNSGDYNTGI
MUL_0965|M.ulcerans_Agy99 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_0207|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv0304c|M.tuberculosis_H37Rv GNTGNTNTGLFNSGDVNTGAFNPGSFNTGSFNTGSFNTGGFNPGNTNTGY
Mb0312c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1639|M.marinum_M GNAGATNTGLLNAGLVNTGVGNAGNYNSGGFNAGHTNTGSFNSGDYNTGY
MUL_0965|M.ulcerans_Agy99 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_0207|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv0304c|M.tuberculosis_H37Rv LNIGNYNTGIANTGDVDTGAFITGNYSNGLFLSGDYQGLVGLNLVIDMPL
Mb0312c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1639|M.marinum_M LNPGNYNTGLANSGDVNTGAFISGNYSNGAFWRGDHQGTGISYSVTIPAI
MUL_0965|M.ulcerans_Agy99 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_0207|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv0304c|M.tuberculosis_H37Rv PISLGVNIPIDIPITASAGNITLMGVTIPPTGDIVLSSIAGQRAHFGPIT
Mb0312c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1639|M.marinum_M PININETYSLDIPFTEDIGPRSIASFVIPRQ---SVTVIGIDLLYLGPIT
MUL_0965|M.ulcerans_Agy99 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_0207|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv0304c|M.tuberculosis_H37Rv IPNITVVGPTTTVAIGGPNTAITITGGG-AIRIPLISIPAAPGFGNSTTN
Mb0312c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1639|M.marinum_M IPQINITGPVLSFEIGPATLRLHATGEIGPVEVPIIDIPATPGFGNTTTN
MUL_0965|M.ulcerans_Agy99 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_0207|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv0304c|M.tuberculosis_H37Rv PSSGFFNTGAGGASGFGNFGGANSGFWNLASATSGASGLLNVGALGSGLA
Mb0312c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1639|M.marinum_M PSSGFFNTGDGSVSGFGNFAARTSGFLNVG---SGSSGVQNLGALQSGLA
MUL_0965|M.ulcerans_Agy99 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_0207|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv0304c|M.tuberculosis_H37Rv NVGTTVSGFYNTSTSDLATPAFNSGLANISTSIAGLLRDSTGTMVLNLGL
Mb0312c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1639|M.marinum_M NLGDTVSGAFNTG---LGVPAHVSGVGNVGSELAGFFRDAAGQAPFNLGL
MUL_0965|M.ulcerans_Agy99 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_0207|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv0304c|M.tuberculosis_H37Rv ----------ANHGTLNVGIANLGDYNIGFANLGSANFGSANIGGNNIGG
Mb0312c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1639|M.marinum_M GNIGFGNVGSANVGSFNVGPANMGDYNIGPGNLGNYNVGLGNLGDSSVGL
MUL_0965|M.ulcerans_Agy99 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_0207|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv0304c|M.tuberculosis_H37Rv ANTGIFDIGLANLGS-----------------------------------
Mb0312c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1639|M.marinum_M ANAGDLNVGVANAGSNNFGLANTGSNNIGIGLSGDGQVGFGALNSGTGNI
MUL_0965|M.ulcerans_Agy99 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_0207|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv0304c|M.tuberculosis_H37Rv --------------------------------------------------
Mb0312c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1639|M.marinum_M GLFNSGADNIGLFNSGTGNFGIGNSGDYNTGIGNAGATNTGLLNAGLVNT
MUL_0965|M.ulcerans_Agy99 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_0207|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv0304c|M.tuberculosis_H37Rv --------------------------------------------------
Mb0312c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1639|M.marinum_M GVSNAGNYNSGGFNAGHTNTGSFNSGDYNTGYLNPGNYNTGLVNSGDVNT
MUL_0965|M.ulcerans_Agy99 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_0207|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv0304c|M.tuberculosis_H37Rv --------------------------------------------------
Mb0312c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1639|M.marinum_M GAFISGDYSNGAFWRGDHQGLADISYGITIPEIPAHIEGTIPLAVPVTMT
MUL_0965|M.ulcerans_Agy99 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_0207|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv0304c|M.tuberculosis_H37Rv --------------------------------------------------
Mb0312c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1639|M.marinum_M STNTVIHAVTIPVFDAGFLGIPIDAGPVTIPAIVITGPTLTGIIGGPTSA
MUL_0965|M.ulcerans_Agy99 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_0207|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv0304c|M.tuberculosis_H37Rv --------------------------------------------------
Mb0312c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1639|M.marinum_M ININTGQHVGPIRLSFLDIPAAPGFGNSTTNPSSGFFNLGQGTVSGFGNL
MUL_0965|M.ulcerans_Agy99 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_0207|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv0304c|M.tuberculosis_H37Rv --------------------------------------------------
Mb0312c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1639|M.marinum_M GARTSGFLNVGSGISGVQNVGALQSGLANLGDTVSGAFNTGLGVPAHVSG
MUL_0965|M.ulcerans_Agy99 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_0207|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv0304c|M.tuberculosis_H37Rv --------------------------------------------------
Mb0312c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1639|M.marinum_M LGNAGSELAGFFRDATGHARFNLGLGNIGSGNVGSGNIGGANVGSGNIGD
MUL_0965|M.ulcerans_Agy99 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_0207|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv0304c|M.tuberculosis_H37Rv YNIGFGNFGDDNLGFGNLGSYNVGFGNLGNDNLGFANTGSNNIGFANTGS
Mb0312c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1639|M.marinum_M YNIGPANLGDYNIGLGNLGDSSIGLANAGDHNLGVANAGFNNFGFANTGN
MUL_0965|M.ulcerans_Agy99 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_0207|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv0304c|M.tuberculosis_H37Rv NNIGIGLTGDGQIGFGSLNSGSGNIGLFNSGSGNIGFFNSGNGNVGIGNT
Mb0312c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1639|M.marinum_M NNIGIGLSGDGQVGFGALNSGTGNIGLFNSGTDNIGLFNSGTGNFGIGNS
MUL_0965|M.ulcerans_Agy99 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_0207|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv0304c|M.tuberculosis_H37Rv GTANFGLGNTGSTNTGFFNSGDVNTGIG----------NTGSFNTGSFNP
Mb0312c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1639|M.marinum_M GDYNTGIGNAGATNTGLLNAGLVNTGVGNAGNYNSGGFNTGSTNTGSFNS
MUL_0965|M.ulcerans_Agy99 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_0207|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv0304c|M.tuberculosis_H37Rv GDSNTGDFNPGSYNTGLGNTGDVDTGAFISGSYSNGFLWSGNYQGLIGLH
Mb0312c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1639|M.marinum_M GDYNTGYLNPGNYNTGLANSGDVNTGAFISGDYSNGAFWRGDHQGLVGFS
MUL_0965|M.ulcerans_Agy99 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_0207|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv0304c|M.tuberculosis_H37Rv AALAIPEIALTFGVDIPIHIPIN-----IDAGVVTLQGFSIVAAENN---
Mb0312c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1639|M.marinum_M YAINIPETPGHAEISIPIDIPINGTIGDINTPRVRIPEFPLNVYVFTPIH
MUL_0965|M.ulcerans_Agy99 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_0207|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv0304c|M.tuberculosis_H37Rv -IDFTPIIIPTINITLPTAAITVGGPTTSIGITASAGIGSITIPIIDIPA
Mb0312c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1639|M.marinum_M VGDVGPIVLPPIRITGPTLTGNIGGPTTSIDIGIGGTLGPAKITIIDIPA
MUL_0965|M.ulcerans_Agy99 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_0207|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv0304c|M.tuberculosis_H37Rv TSGFGNSTTSPSSGFFNSGAGSASGFLNVVAGAS-------GISGYLNVG
Mb0312c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1639|M.marinum_M APGFGNSTTSPSSGFFNSGDGSVSGFGNFGDHTSGLVNFGSGNSGAQNVG
MUL_0965|M.ulcerans_Agy99 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_0207|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv0304c|M.tuberculosis_H37Rv ALGSGVTNVGHTVSGFYNASALDLVTPAFAS-------GLMRDGMGTMTL
Mb0312c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1639|M.marinum_M ALQSGLANLGDTVSGAFNTGLGVPAHVSGVGNVGSELAGFFRDATGHAPF
MUL_0965|M.ulcerans_Agy99 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_0207|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv0304c|M.tuberculosis_H37Rv NLGLANLGSNNAGFGNTGIFDVGVANLGNYNIG----------FGNFGDD
Mb0312c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1639|M.marinum_M NLGLGNIGFGNVGSANAGNFNVGSANIGDYNIGPGNLGDYNIGLGNLGDS
MUL_0965|M.ulcerans_Agy99 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_0207|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 -----MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAA
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv0304c|M.tuberculosis_H37Rv NLGFANLGSYNIGVANTGSNNIGFANTGSNNIGIGLTGTGQIGIGALNSG
Mb0312c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1639|M.marinum_M SIGLANAGDHNLGVANAGFNNFGFANTGNNNIGIGLSGDGQVGIGALNSG
MUL_0965|M.ulcerans_Agy99 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_0207|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------MMFLAPPGGPGPISAAIQLTSTGSEA
MSMEG_0868|M.smegmatis_MC2_155 LAPESPLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNT
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv0304c|M.tuberculosis_H37Rv SGNIGLFNSGDGNIGFFNSGTGNFGIGNTGTGNFGIGNSGSTSTGLFNSG
Mb0312c|M.bovis_AF2122/97 -----MFNSGDGNIGFFNSGTGNFGIGNTGTGNFGIGNSGSTSTGLFNSG
MMAR_1639|M.marinum_M TGNIGLFNSGTDNIGLFNSGTGNFGIGNSGDYNTGIGNAGATNTGLLNAG
MUL_0965|M.ulcerans_Agy99 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_0207|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------MVTFGGG
Mvan_1264|M.vanbaalenii_PYR-1 TEP--------------------------------------WYVVSFGGS
MSMEG_0868|M.smegmatis_MC2_155 TDQPTSDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTT
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv0304c|M.tuberculosis_H37Rv DGNTGGFNPGNFNTGNFNTGSFNTGGFNAGNTNTGHFNTGNYNTGIANTG
Mb0312c|M.bovis_AF2122/97 DGNTGGFNPGNFNTGNFNTGSFNTGGFNAGNTNTGHFNTGNYNTGIANTG
MMAR_1639|M.marinum_M LVNTGVGNAGNYNSGGLNAGHTNTGSFNSGDYNTGYLNPGNYNTGMVNSG
MUL_0965|M.ulcerans_Agy99 -------------------------------MNFIMLPP------EINSA
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_0207|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ATPTP----------------------------------------TSLGA
Mvan_1264|M.vanbaalenii_PYR-1 GAPTP----------------------------------------NNLAA
MSMEG_0868|M.smegmatis_MC2_155 LIPNAPTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVAS
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv0304c|M.tuberculosis_H37Rv DVSTGAFISGNYSNGILWRGDYQGLIGYSYALTIPEIPAHLDVNIPIDIP
Mb0312c|M.bovis_AF2122/97 DVSTGAFISGNYSNGILWRGDYQGLIGYSYALTIPEIPAHLDVNIPIDIP
MMAR_1639|M.marinum_M DVNTGAFISGDYSNGAFWRGDHQGLVGFSYGFTIPALPAQLEAQIPVNIP
MUL_0965|M.ulcerans_Agy99 RIFAGAGVGPTLAAAAAWD----------------ALAADLASAAQSFAA
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_0207|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK AAVDLS------------------------GTSCG----------LICNG
Mvan_1264|M.vanbaalenii_PYR-1 SLVDLS------------------------GTSCG----------LICNG
MSMEG_0868|M.smegmatis_MC2_155 AVLDPTQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNG
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv0304c|M.tuberculosis_H37Rv ITGSFTDLVVDNFTIPIIGFESFAFSFHIHTEPDIGPIIVPSFVLSVPTF
Mb0312c|M.bovis_AF2122/97 ITGSFTDLVVDNFTIPIIGFESFAFSFHIHTEPDIGPIIVPSFVLSVPTF
MMAR_1639|M.marinum_M ATATAGDTTIHSATFPAIHFDTFGLLP--QSNGTFGPVTLPDITLSGPTF
MUL_0965|M.ulcerans_Agy99 ITVGLVGEAWQGAAATAMAAAARPYASWLGTAAARAAVTAAQANAAAAVF
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_0207|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK QDGTGQN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGG
Mvan_1264|M.vanbaalenii_PYR-1 QDGTGQN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGG
MSMEG_0868|M.smegmatis_MC2_155 INGTADNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGG
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv0304c|M.tuberculosis_H37Rv AIAVGGPTTAINISATAGLGPITIPIIDIPAAPGIGNSTTSPSSGFFNTG
Mb0312c|M.bovis_AF2122/97 AIAVGGPTTAINISATAGLGPITIPIIDIPAAPGIGNSTTSPSSGFFNTG
MMAR_1639|M.marinum_M SLLMGGPDTVVGIKAGGVAGPVTFSFIDIPAAPGFGNTTATPSSGFFNSG
MUL_0965|M.ulcerans_Agy99 EAAQAATAHPELVAANRNQ------LVSLVVSNLFGQNAPAIASTEAAYD
MAB_4284c|M.abscessus_ATCC_199 -----MSIIDFILNLFRDPVEAASYVADPEAALANAGLSAVSAAQVGAVM
MAV_0207|M.avium_104 ----------------------MPNRRRRKLSTAMSAVAALAVASPCAYF
Mflv_5091|M.gilvum_PYR-GCK NGLGGGNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGA
Mvan_1264|M.vanbaalenii_PYR-1 NGLGSGDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGA
MSMEG_0868|M.smegmatis_MC2_155 VGWAGLDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGT
TH_3810|M.thermoresistible__bu ---VDGDGGSGGRTGLFSKLSRGGDGGDGGLG-------------GNGGH
Rv0304c|M.tuberculosis_H37Rv AGTASGFGNVGGNTSGLWNLASAASGVSGLLNVGALGSGVAN----VGNT
Mb0312c|M.bovis_AF2122/97 AGTASGFGNVGGNTSGLWNLASAASGVSGLLNVGALGSGVAN----VGNT
MMAR_1639|M.marinum_M AGSASGFGNSGADNSGLLNLAFGSS---GYQNVGALQSGIAN----LGNT
MUL_0965|M.ulcerans_Agy99 QLWAQDVAAMAGYHSGAS--AVAAQLAPWQQALRTLQNRVAG----ATTA
MAB_4284c|M.abscessus_ATCC_199 PVVAESVASNYGYQSQWVNTGNPIHDLSGNLQNYYAAQPDGP--SILSPS
MAV_0207|M.avium_104 LVYESTAGNKAPEHHEFKQAAVMSDLPGELMG------------------
. .
Mflv_5091|M.gilvum_PYR-GCK TGATGVTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG----------
Mvan_1264|M.vanbaalenii_PYR-1 TGATGVTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG----------
MSMEG_0868|M.smegmatis_MC2_155 GGGTGGTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIA
TH_3810|M.thermoresistible__bu GGGTGIIS--------------------LLSLAGNGGNGG----------
Rv0304c|M.tuberculosis_H37Rv ISGIYNTSPLDLGTPAFGSGLANI----AGLLQGGAGTT-----------
Mb0312c|M.bovis_AF2122/97 ISGIYNTSPLDLGTPAFGSGLANI----AGLLQGGAGTT-----------
MMAR_1639|M.marinum_M MSGVYNTG---LAVPAHVSGIGNIGHNLAGLLRGTAGQVP----------
MUL_0965|M.ulcerans_Agy99 LP-----------PPGPAA---------AAALPGAAAVGF----------
MAB_4284c|M.abscessus_ATCC_199 LLSPRDNDFLSHNDTDFASHNPIASGNQVMSPSGNVDSFN----------
MAV_0207|M.avium_104 ------------------------------ALSQGLSQFG----------
Mflv_5091|M.gilvum_PYR-GCK ----AVGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG----AVGAAG-
Mvan_1264|M.vanbaalenii_PYR-1 ----AVGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----AIGTAG-
MSMEG_0868|M.smegmatis_MC2_155 GPNVTVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGG
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv0304c|M.tuberculosis_H37Rv ----ILDLAGLGNLNVGLANLGGSNFGIGNTGIFNVGFANVGNHNIG---
Mb0312c|M.bovis_AF2122/97 ----ILDLAGLGNLNVGLANLGGSNFGIGNTGIFNVGFANVGNHNIG---
MMAR_1639|M.marinum_M ---VNVGFANNGAGNVGFGNVGFSNVGSGNIGSFNVGSGNIGDYNIGPGN
MUL_0965|M.ulcerans_Agy99 ---PVLHIGNIGFANLSVGNIGDYNLGSGNTGSFNLGSGNIGDASLG---
MAB_4284c|M.abscessus_ATCC_199 ----RGPLLDLSFGDLQFGNRDTTAIGDGAVAVGGSNSGP----------
MAV_0207|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ------AAGTVGTAGATGGTGTGANGGAGGVG-----GVGGTGAAGAAGG
Mvan_1264|M.vanbaalenii_PYR-1 ------VAGAAGTAGATGGTGVGGNGGAGQAG-----GIGGTGAAGAAGQ
MSMEG_0868|M.smegmatis_MC2_155 TVDGHAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGG
TH_3810|M.thermoresistible__bu -------------NGYRTTDNNALDGGHGGNG-----------------G
Rv0304c|M.tuberculosis_H37Rv -------LANLGNYSVGFANSGNYHIGIANTG--------SANIGFANTG
Mb0312c|M.bovis_AF2122/97 -------LANLGNYSVGFANSGNYHIGIANTG--------SANIGFANTG
MMAR_1639|M.marinum_M LGDYNIGLGNLGDSSIGFGNAGDHNVGVANAG--------FNNFGFANTG
MUL_0965|M.ulcerans_Agy99 -------SGNAGDSNVGFGNFGSNNVGIGNNG--------NNNIGIGLNG
MAB_4284c|M.abscessus_ATCC_199 -------IASGQGSTAVNGDVRDSNIINADHG---------SNVGVDQSQ
MAV_0207|M.avium_104 ---------------INLPPVPALSGGATSTP------------GLASPG
Mflv_5091|M.gilvum_PYR-GCK AGGLGETGTTGGAGGVG--------------------GQGTAGGTGGVGG
Mvan_1264|M.vanbaalenii_PYR-1 AGTAGETGVTGGVGGIG--------------------GQGTEGGTGGVGG
MSMEG_0868|M.smegmatis_MC2_155 DGGHSTGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGG
TH_3810|M.thermoresistible__bu NVGFFSLFNLGGAGGWG--------------------GSGVDG-------
Rv0304c|M.tuberculosis_H37Rv SGNIGIGLTGTGQIGFG------------------SFNSGSHNIGLFNSG
Mb0312c|M.bovis_AF2122/97 SGNIGIGLTGTGQIGFG------------------SFNSGSHNIGLFNSG
MMAR_1639|M.marinum_M SNNIGIGLNGDGQVGFG------------------ALNSGTGNIGLFNSG
MUL_0965|M.ulcerans_Agy99 DDLIGIGALNSGAGNLG------------------FGNSGTNNIGFFNSG
MAB_4284c|M.abscessus_ATCC_199 TRVGGDYTNVSGHG-----------------------SADIDKSVTVVDD
MAV_0207|M.avium_104 LGSPGLGSPGLGTPGLG--------------------TPGLTNPGLTSPG
* .
Mflv_5091|M.gilvum_PYR-GCK IGGAG----------STGAVGG-------VGGKG----IQGGQG------
Mvan_1264|M.vanbaalenii_PYR-1 VGGVG----------ATGGAGG-------VGGKG----IQGGQG------
MSMEG_0868|M.smegmatis_MC2_155 MGEIYSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGK
TH_3810|M.thermoresistible__bu ----------------VDVVGG----------------------------
Rv0304c|M.tuberculosis_H37Rv DGNVG---------FFNSGTGNVGIGNTGTANFGIANSGSFNTG------
Mb0312c|M.bovis_AF2122/97 DGNVG---------FFNSGTGNVGIGNTGTANFGIANSGSFNTG------
MMAR_1639|M.marinum_M TDNIG---------LFNSGTG----------NFGIGNSGDYNTG------
MUL_0965|M.ulcerans_Agy99 DNNIG---------FFNSGSG----------NFGFENAGDINTG------
MAB_4284c|M.abscessus_ATCC_199 HSQRN----------TTNINDS----------------------------
MAV_0207|M.avium_104 ATSPG---------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK -------LQGGKGGDGGAGGKGGDADSMGS------------------AG
Mvan_1264|M.vanbaalenii_PYR-1 -------LQGGQGGDGGTGGTGGDATSMGE------------------AG
MSMEG_0868|M.smegmatis_MC2_155 ASGTAKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAAS
TH_3810|M.thermoresistible__bu ------------NPDGGTPG------------------------------
Rv0304c|M.tuberculosis_H37Rv -------LGNTGSTNTGLFNPGNVNTGVGNTGSI-------------NTG
Mb0312c|M.bovis_AF2122/97 -------LGNTGSTNTSLFNPGNVNTGVG------------------NTG
MMAR_1639|M.marinum_M -------IGNAGATNTGLLNAGLVNTGVG------------------NAG
MUL_0965|M.ulcerans_Agy99 -------FWNGRDTNTGFGNSGLSNFGFG------------------NSG
MAB_4284c|M.abscessus_ATCC_199 -------FNTDRSTNIGSGNTTNTEIGSHN------------------QA
MAV_0207|M.avium_104 ------------LTSPGLTSPGLTSPGLTS--------------------
. . .
Mflv_5091|M.gilvum_PYR-GCK ATGGKGGNGGNGGRGGLFG---------------KGGNAGNGAD------
Mvan_1264|M.vanbaalenii_PYR-1 ATGGKGGNGGNGGRGSLFG---------------RGGNAGNGGN------
MSMEG_0868|M.smegmatis_MC2_155 ANGAVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAY
TH_3810|M.thermoresistible__bu AHGESHTPGVYTDRQ-----------------------------------
Rv0304c|M.tuberculosis_H37Rv SINTGSFNTGSTNTGSFNLGDHNTGSFNSGDYNTGYFNAGDYNTG-----
Mb0312c|M.bovis_AF2122/97 SINTGSFNTGSTNTGSFNLGDHNTGSFNSGDYNTGYFNAGDYNTG-----
MMAR_1639|M.marinum_M NYNSGGFNTGSTNTGSFNPGDYNTGGLNQGDYNTGYLNSGDYNTG-----
MUL_0965|M.ulcerans_Agy99 VNNVGAGNGGSSNVGLGNAGLLNTGSFNSGKFNTGDFNSGSMNTG-----
MAB_4284c|M.abscessus_ATCC_199 NIGTSTSAGGSAAVGGNAG-------------------------------
MAV_0207|M.avium_104 -PGAAPTTPGLTAPG-----------------------------------
.
Mflv_5091|M.gilvum_PYR-GCK ----------------GGTGGAGGAGGTGG-TGGAGGTGG----------
Mvan_1264|M.vanbaalenii_PYR-1 ----------------GGTGGNGGNGGTGG-TGGNGGTGG----------
MSMEG_0868|M.smegmatis_MC2_155 DPNGPAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQ
TH_3810|M.thermoresistible__bu --------------------GEDGEDGTGTGIGGRGGNGG----------
Rv0304c|M.tuberculosis_H37Rv --------------VANTGNVNTGAFISGNYSNGFFWRGDYQGLIGLSTT
Mb0312c|M.bovis_AF2122/97 --------------VANTGNVNTGAFISGNYSNGFFWRGDYQGLIGLSTT
MMAR_1639|M.marinum_M --------------FVNAGDVNTGAFISGNYSNGFFARGDYQNLIGWSYS
MUL_0965|M.ulcerans_Agy99 --------------YFNSSGHNTGLGNSGFTNTGFFNSGDLNTGMGSPED
MAB_4284c|M.abscessus_ATCC_199 ------------------LAGNAGLAGNAGLAGNAGLAGN----------
MAV_0207|M.avium_104 --------------------ALPTTPGGGVATPGAG--------------
. .
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 HSTGQT--------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv0304c|M.tuberculosis_H37Rv ITIPEIPYRYDLSVPIDIPITGTVVATTPNSFTIPGFQIRVLLGP--AAV
Mb0312c|M.bovis_AF2122/97 ITIPEIPYRYDLSVPIDIPITGTVVATTPNSFTIPGFQIRVLLGP--AAV
MMAR_1639|M.marinum_M ITVSEFPAYGTLDIPVYIPFTGAIGPITIQEFTIPSLPLDALVYINGTPI
MUL_0965|M.ulcerans_Agy99 QSVANSGFRN----------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_0207|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK -------------------------------TGGTGGIGGAGSTGGTGGT
Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------TGGTGGIGGAGSTGGTGGT
MSMEG_0868|M.smegmatis_MC2_155 ------------------------------DTGGNGGRGGDGGTFVNAGA
TH_3810|M.thermoresistible__bu ------------------------------SSSGTHPMAEDG--------
Rv0304c|M.tuberculosis_H37Rv LVNEMIGPITIDVN--QVIAIDSPIQQTIS-MVGTGGFGPIPIGISIGGT
Mb0312c|M.bovis_AF2122/97 LVNEMIGPITIDVN--QVIAIDSPIQQTIS-MVGTGGFGPIPIGISIGGT
MMAR_1639|M.marinum_M PIFYDFGPITVDETTTDPIALNFVWDQLYHYEVGPRTFGPYEIPLFSFPG
MUL_0965|M.ulcerans_Agy99 --------------------------------AGSGNSGFNNTGSFS---
MAB_4284c|M.abscessus_ATCC_199 --------------------------------AGLAGNAGLAGNAGLAGN
MAV_0207|M.avium_104 ---------------------------------LNPALSNPGLTSPAGTA
.
Mflv_5091|M.gilvum_PYR-GCK GGTGGTGGTGGTG-GTGGTGGTGGTG--GKGGTGGTGGAGGTG----GDG
Mvan_1264|M.vanbaalenii_PYR-1 GGTGGTGGTGGTG-GTGGTGGTGGTG--GKGGTGGTGGDGGTG----GTG
MSMEG_0868|M.smegmatis_MC2_155 NGNGGAGGAGGVSEGEGGTGGHGGDG--GRGGDGALGGNGGTGGVGLGNG
TH_3810|M.thermoresistible__bu EHVKALDGRPGLD---GGNGSHGGNG--GHGGRGGFLGIGGSG-------
Rv0304c|M.tuberculosis_H37Rv PGFGNSTTGPSSGFFHTGAGHVSGFGNFGAGNMSGSGNFGAGNSGFFN--
Mb0312c|M.bovis_AF2122/97 PGFGNSTTGPSSGFFHTGAGHVSGFGNFGAGNMSGFGNFGAGNSGFFN--
MMAR_1639|M.marinum_M PGFANSTTSPSSGFFNSGTGPTSGFFNSGAGSLSGLINLGANNSGFANT-
MUL_0965|M.ulcerans_Agy99 SGFFNSTNS-NSEFLNAGGTVNSGINNSGN-TNAGIGNLGDDNFGLFNNG
MAB_4284c|M.abscessus_ATCC_199 AGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAG-LAGNA
MAV_0207|M.avium_104 PGLGSPTVAPSEVPIDSGAGLDPGAG--GTYPILGDPSTFGNAS------
. . . * . .
Mflv_5091|M.gilvum_PYR-GCK GTGGTGGTGGTG---------GTGGTGGTGGAG-----------DGTGGT
Mvan_1264|M.vanbaalenii_PYR-1 GTGGTGGTGGTG---------GTGGTGGTGGAG-----------DGLGGT
MSMEG_0868|M.smegmatis_MC2_155 GKGGNGGNGGNGGTYVDPSHTGAGGNGGNGGAGRIRVNNGTATGTATGGN
TH_3810|M.thermoresistible__bu GWGGHGGNGGD-----------TDADGGNGGDG---------------GN
Rv0304c|M.tuberculosis_H37Rv --AGGLGNSGLLNFGALQSGLANLGNTISGVYNTSTLDLATPAFGSGIAN
Mb0312c|M.bovis_AF2122/97 --AGGLGNSGLLNFGALQSGLANLGNTISGVYNTSTLDLATPAFGSGIAN
MMAR_1639|M.marinum_M -GIGGLGNSGFINDGALQSGMANVGNTISGIYNSTTLDPTAVANVSGIAN
MUL_0965|M.ulcerans_Agy99 TFNTGAGNSSGGAVFPYTSGLFNSGNGSSGVFNAGD-EQSGFFGTSGLVL
MAB_4284c|M.abscessus_ATCC_199 GLAGNAGLAGNAG--------LAGNAGLAGNAG-------------LAGN
MAV_0207|M.avium_104 ----PIGGGGTG----------LGGGSSSGGSG-----------------
* .. * .
Mflv_5091|M.gilvum_PYR-GCK GGTGG----TGGQGGQGGQGG-----------------TGGTGGQGG-LG
Mvan_1264|M.vanbaalenii_PYR-1 GGTGG----TGGFGGQGGQGG-----------------TGGTGGQGG-LG
MSMEG_0868|M.smegmatis_MC2_155 GGNGGNGDADGHRGGKGGDGGEALIRATVIGSNASGTATGGDGGNGGTLG
TH_3810|M.thermoresistible__bu GGSAG---------------------------------RGGTGGLRGVFG
Rv0304c|M.tuberculosis_H37Rv IGANLAGLFLDNTGNLTLNFG----------VANQGGLNAGIGNLGSVNI
Mb0312c|M.bovis_AF2122/97 IGANLAGLFLDNTGNLTLNFG----------VANQGGLNAGIGNLGSVNI
MMAR_1639|M.marinum_M TGVDLAGVFRG--ASRIHNLG----------FANLGIANLGSANIGDLNL
MUL_0965|M.ulcerans_Agy99 TGTDGLA------ATTTSGLP----------ALDLPAPNLGIGNAGVGNL
MAB_4284c|M.abscessus_ATCC_199 AGLAG---------------------------------NAAVAGNAAVAG
MAV_0207|M.avium_104 ------------------------------------------GLVNDVMQ
.
Mflv_5091|M.gilvum_PYR-GCK GGGGTG-----------------------GQGGTGGTGGQGGTGGTGGTG
Mvan_1264|M.vanbaalenii_PYR-1 GVGGTG-----------------------GTGGTGGTGGQGGTGGTGGTG
MSMEG_0868|M.smegmatis_MC2_155 ATNGTGGAATIVAYNVVQANPQASGTATDGHGGSGINGGHGGNGGQGTIE
TH_3810|M.thermoresistible__bu INGGNG------------------------RAGLGGRGXXXXGGGVGAAV
Rv0304c|M.tuberculosis_H37Rv GFVNTG----------------------DSNLGIGNLGDLNFGGVNIGGN
Mb0312c|M.bovis_AF2122/97 GFVNTG----------------------DSNLGIGNLGDLNFGGVNIGGN
MMAR_1639|M.marinum_M GGANFG----------------------SANIGSGNIGFGNVGGGNVGSL
MUL_0965|M.ulcerans_Agy99 GLGNIG----------------------DYNLGSGNTGDANFGSGNIGAL
MAB_4284c|M.abscessus_ATCC_199 NAAVAG------------------------NAAVGGVLNTGVSGAIGGSS
MAV_0207|M.avium_104 AANQLG----------------------------AGQAIDLLKGLVMPAI
* . .
Mflv_5091|M.gilvum_PYR-GCK GTG---------GTGGAGGDGGLGGLGGFGGSGGTGGQGGLGGPG-----
Mvan_1264|M.vanbaalenii_PYR-1 GTG---------GTGGAGGDGGLGGLGGFGGVGGTGGQGGQGGPG-----
MSMEG_0868|M.smegmatis_MC2_155 ANGPSAV-ASGIGAGGNGGDGIDGGLGGNGGDGVVNTTANAANPG-----
TH_3810|M.thermoresistible__bu RSG----------------NGVFSGGGGTPSAGFGVPTTIQFPAG-----
Rv0304c|M.tuberculosis_H37Rv NIGIANTGIFDIGLANLGSYNIGLANLGDDNLGFGNAGSYNIGFANFGSD
Mb0312c|M.bovis_AF2122/97 NIGIANTGIFDIGLANLGSYNIGLANLGDDNLGFGNAGSYNIGFANFGSD
MMAR_1639|M.marinum_M NLGFGNLGDHNIGPGNLGDYNIGLGNLGDSNVGFGNAGDHNVGVG-----
MUL_0965|M.ulcerans_Agy99 NLGSGNHGDANLGFGNTGDNNIGLFNSGDNNVGFFNSGGANFGLA-----
MAB_4284c|M.abscessus_ATCC_199 HVG----GAINESLGGSGSVGGSTAVGGGAHTGVGGGVSTGVGVG-----
MAV_0207|M.avium_104 TQG------------------MHGGAAAGALPGAAGALP-----------
* . *
Mflv_5091|M.gilvum_PYR-GCK -------GSTGGAGGAGG--QAGTAGKGGLFG----GSGSAGKAGATGAA
Mvan_1264|M.vanbaalenii_PYR-1 -------GSTGGAGGAGG--QAGVAGKGGLFG----GSGSAGTAGVTGAS
MSMEG_0868|M.smegmatis_MC2_155 -------SATGTATGGDGGKATGTASQGGNGGPSWVQSGYGSTLGGNATG
TH_3810|M.thermoresistible__bu -------SCTSRAVSREG------------------------IMPSSRAA
Rv0304c|M.tuberculosis_H37Rv NLGFANTGSYNIGFANTGNNNIGVGLTGNGQIGIGSLNSGSNNIGLFNSG
Mb0312c|M.bovis_AF2122/97 NLGFANTGSYNIGFANTGNNNIGVGLTGNGQIGIGSLNSGSNNIGLFNSG
MMAR_1639|M.marinum_M -----NAGFNNFGFANTGSNNIGIGLSGDGQVGFGALNSGTGNIGLFNSG
MUL_0965|M.ulcerans_Agy99 -----NSGDTNTGLWNAGSTNTGFGNAGSADFGFG--NAGDRNMGFGNAG
MAB_4284c|M.abscessus_ATCC_199 ---SHVGGGISESLGGSGSVGGSTAVGGGAHTGVGGGVSTGVGVGSHVGG
MAV_0207|M.avium_104 -------GAAGALPGAAG-----------------------ALPGAAGAL
. . *
Mflv_5091|M.gilvum_PYR-GCK GASGGKGAQGATGAQGATG------AQGATG-ATGAAGKAGATGAAGAAG
Mvan_1264|M.vanbaalenii_PYR-1 GASGGKGAQGATGAQGATG------AQGATG-ATGASGAQGSAGSAGSAG
MSMEG_0868|M.smegmatis_MC2_155 TATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTATGGDGGAATTAG
TH_3810|M.thermoresistible__bu SARAG---------------------------AACASSTSRSRRSFCCSR
Rv0304c|M.tuberculosis_H37Rv SGNIGFFNSGTGNVGIFNTG------TGNFGLANSGGFNTGIGNAGSTNT
Mb0312c|M.bovis_AF2122/97 SGNIGFFNSGTGNVGIFNAG------TGNFGLANSGGFNTGIGNAGSTNT
MMAR_1639|M.marinum_M TDNIGLFNSGTGNIGLFNSG------TGSFGIGNSGNYNTGIGNAGATNT
MUL_0965|M.ulcerans_Agy99 AANMGAGNSGSYNTGSFNSG------TLNTGDFNGGDHNTGWGNSGNTNT
MAB_4284c|M.abscessus_ATCC_199 GISESLGGSGSVGGSTAVGG--------GAHTGVGGGVNTGVGVGSHVGG
MAV_0207|M.avium_104 PAAAG----------------------------AAGALPAAAGAAPALPP
. .
Mflv_5091|M.gilvum_PYR-GCK AAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAGKAGATGTT
Mvan_1264|M.vanbaalenii_PYR-1 VAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAGKAGATGTT
MSMEG_0868|M.smegmatis_MC2_155 ATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGKGADGWVQAYDPA
TH_3810|M.thermoresistible__bu A-------------------------------------------------
Rv0304c|M.tuberculosis_H37Rv GVFNP----------GDLNT---GSFNPGSFNTGGFNPGSGNTGYLNTGD
Mb0312c|M.bovis_AF2122/97 GVFNP----------GDLNT---GSFNPGSFNTGGFNPGSGNTGYLNTGD
MMAR_1639|M.marinum_M GLFNTGLVNTGVGNAGNYNS---GGFNTGSTNTGSFNSGDHNTGYLNSGD
MUL_0965|M.ulcerans_Agy99 GGINS----------GDLNTGFGSSADQAVTNSGFGNNGSGNSGFNNTGD
MAB_4284c|M.abscessus_ATCC_199 GISES-------------------LGGSGSVGGSTAVGGGAHTSAINDAL
MAV_0207|M.avium_104 V-------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GATG--------AAGEDGDAGSGGSG-INGGAGGAGG-----------AG
Mvan_1264|M.vanbaalenii_PYR-1 GATG--------AAGDAGDPGSEAVD-INGGAGGAGG-----------AG
MSMEG_0868|M.smegmatis_MC2_155 GPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGNTSVWKSGGQTAD
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv0304c|M.tuberculosis_H37Rv YNTGVANTGDVDTGAFITGSYSNGFLVSGDYQGLIGLPLLGIPVTPGYFN
Mb0312c|M.bovis_AF2122/97 YNTGVANTGDVDTGAFITGSYSNGFLVSGDYQGLIGLPLLGIPVTPGYFN
MMAR_1639|M.marinum_M YNTGLANSGDVNTGAFISGNYSNGFFVDGDHQGLIDG-------TPGFFN
MUL_0965|M.ulcerans_Agy99 TNSGFHN---ANTSALFSG--HSGLLNAGGSQ-------------SVGIN
MAB_4284c|M.abscessus_ATCC_199 GGSGSVGGSTAVGGGAHTSAINESMN-----------------------S
MAV_0207|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GEGGEGGDGGKGGAGAE---------------------GGAGGGGGAGGS
Mvan_1264|M.vanbaalenii_PYR-1 GEGGEGGAGGAGGDGSE---------------------GGAGGSGGAGGS
MSMEG_0868|M.smegmatis_MC2_155 GEHNTGGNGGNGGDGSEPGPGGN-------------GAGGAGGNGGTGGT
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv0304c|M.tuberculosis_H37Rv LTGGPSSGFFNSGAGSVSGFVN--------------SGAGLSGYLNTGAL
Mb0312c|M.bovis_AF2122/97 LTGGPSSGFFNSGAGSVSGFVN--------------SGAGLSGYLNTGAL
MMAR_1639|M.marinum_M STTNPSSGLLNSGEGSESGVGNYGVGNSGFLNFASVTGAGSSGLLNVGAL
MUL_0965|M.ulcerans_Agy99 NTGSFNTVLFNTGFRT-AGIAN----------------SATNGLLTA---
MAB_4284c|M.abscessus_ATCC_199 SINASHSSSMNESFGSSMGSHG----------------AAGTGFEAQGHA
MAV_0207|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GAGGAG--GAGGSGGSGGSGGSGGSGGAAGDSDD--------------
Mvan_1264|M.vanbaalenii_PYR-1 GTGGAG--GAGGSGGSGGSGGAGGSGGAAGDSD---------------
MSMEG_0868|M.smegmatis_MC2_155 TAGGSGNGGNGGNGGNGGADGTPGTAGTTGANNP--------------
TH_3810|M.thermoresistible__bu ------------------------------------------------
Rv0304c|M.tuberculosis_H37Rv GSGVANVGNTISGWLNASALDLATPGFLSGIGNFGTNLAG-FFRG---
Mb0312c|M.bovis_AF2122/97 GSGVANVGNTISGWLNASALDLATPGFLSGIGNFGTNLAG-FFRG---
MMAR_1639|M.marinum_M QSGILNLGSTISGFGNTGS---VTPAFVSGVANAGTRLSGFFFRGTGP
MUL_0965|M.ulcerans_Agy99 TSGVANSGNNSSGGFNANP-----------------DQSG-FFN----
MAB_4284c|M.abscessus_ATCC_199 QGHASETAHTTLPGAEHH------------------------------
MAV_0207|M.avium_104 ------------------------------------------------