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SFAVLPPEINSARLYVGAGLAPMLDAAAAWDGLADELGSAAASFSAVTAGLAGSSWLGAASTAMTGAAAP YLGWLSAAAAQAQQAATQTRLAAAAFEAALAATVHPAIISANRALFVSLVVSNLLGQNAPAIAATEAAYE QMWAQDVAAMFGYHAGASAAVSALTPFGQALPTVAGGGALVSAAAAQVTTRVFRNLGLANVGEGNVGNGN VGNFNLGSANIGNGNIGSGNIGSSNIGFGNVGPGLTAALNNIGFGNTGSNNIGFGNTGSNNIGFGNTGDG NRGIGLTGSGLLGFGGLNSGTGNIGLFNSGTGNVGIGNSGTGNWGIGNSGNSYNTGFGNSGDANTGFFNS GIANTGVGNAGNYNTGSYNPGNSNTGGFNMGQYNTGYLNSGNYNTGLANSGNVNTGAFITGNFNNGFLWR GDHQGLIFGSPGFFNSTSAPSSGFFNSGAGSASGFLNSGANNSGFFNSSSGAIGNSGLANAGVLVSGVIN SGNTVSGLFNMSLVAITTPALISGFFNTGSNMSGFFGGPPVFNLGLANRGVVNILGNANIGNYNILGSGN VGDFNILGSGNLGSQNILGSGNVGSFNIGSGNIGVFNVGSGSLGNYNIGSGNLGIYNIGFGNVGDYNVGF GNAGDFNQGFANTGNNNIGFANTGNNNIGIGLSGDNQQGFNIASGWNSGTGNSGLFNSGTNNVGIFNAGT GNVGIANSGTGNWGIGNPGTDNTGILNAGSYNTGILNAGDFNTGFYNTGSYNTGGFNVGNTNTGNFNVGD TNTGSYNPGDTNTGFFNPGNVNTGAFDTGDFNNGFLVAGDNQGQIAIDLSVTTPFIPINEQMVIDVHNVM TFGGNMITVTEASTVFPQTFYLSGLFFFGPVNLSASTLTVPTITLTIGGPTVTVPISIVGALESRTITFL KIDPAPGIGNSTTNPSSGFFNSGTGGTSGFQNVGGGSSGVWNSGLSSAIGNSGFQNLGSLQSGWANLGNS VSGFFNTSTVNLSTPANVSGLNNIGTNLSGVFRGPTGTIFNAGLANLGQLNIGSANLGDFNLGSGNVGSF NVFSGNQGSYNIGPANLGNYNIGFANLGNYNIGFGNAGDFNQGFANTGNNNIGFANTGNNNIGIGLSGDN QQGFNFAGGWNSGTANIGLFNSGTNNVGIGNSGTGNWGIGNSGSGNTGIGNTGSTNTGFFNTGIVNTGVA NAGSYNTGWYNTGDTNTGIANLGDFNTGFYNTGNFSTGFANQGDIATGAFITGDMGNGAFWRGDQQGLFS AGYRVHVPEIPAHVTVEVPVNIPITASFTNTVYSGITLEQINFGFTIDIAGIPLLAGAISKAVLPPITGT GPAITVNIGDPGGSTAIRIPATASVGPFDVTFVNIAATTGFFNATTDPSSGFFNGGPGTVSGIANIGANI SGFQNVANSATSGFNNYGSLQSGLANLGDTVSGVFNTGIGAPANVSGMFNIGSNLAGFFHDQATGMSMFN LGLGNIGQFNVGFSNVGDSNAGLANIGSFNLGSGNLGSFNVFGGNQGSYNIGPANLGNYNIGLGNLGSYN FGFGNAGDFNLGFANTGNNNIGFANTGNNNIGIGLSGDNQQGFNFAGGWNSGSGNSGLFNSGTNNIGLFN SGTGNIGIGNSGTGNWGIANTGDTNTGIFNTGDVNTGLLNAGNVNTGIFNTGHYNTGSFNAGSFNTAGFN PGSYNTGYLNTGSYNTGLANSGDVNTGGFITGNYSNGFWWRGDYQGLAGISQTITVPDTAVPVKLHVPIF LDIPVTGTLGTFTVHGFRFPEITGDIFLIGIPFNAATLDAFSFPNISIVLPNIGINLGSGPDPLIDIAGT GGLLPIKIPLIDIPAAPGFGNSTTTPSSGFFNAGTGTVSGVGNVGSNSSGFFNLTSGSSGISGVQNFGEL ISGGFNFGNTVSGLVNASTLGLSMPANLSGGGNVGATVAGFVNNTQILNLGFGNVGSGNVGHGNIGDSNV GLGNLGNANVGHGNIGSFNVFSGNRGSYNIGPANLGNYNIGLGNLGSYNFGFGNAGDFNLGFANSGSNNI GFANTGNNNIGIGLSGHNQQGFGSWNSGTANTGLFNSGTNNIGLFNSGTGNIGIGNSGIGNTGIGNPGVG NTGLGNSGTGNWGLWNPGTGNMGVANVGTYNTGGYNVGSTNTGIANVGIANTGSYNTGSTNTGSFNDGDF NTGFYNTGDYNTGFYNTGDVNTGAFIGGNFSNGAFWQSDHQGQWGAHYAITVPQIPLLNFSLNIPVNIPI HLDFGTLAVNGFQIPAITLRALGVTHFSVGPIIVPRIAGTLPVIDINIGDPGGSSSIPITITSGAGPVVI PLLDIPPAPGFGNSTTGPSSGFFNSGTGSSSGFGNVGANNSGFWNTAFAGIGNSGLQNFGSLQSGWANLG NTVSGFYNTSAADFATPANLSGLSNVGADLTGVLRGPNGSTFNAGLANLGQFNVGSANLGSANLGSANLG SANLGNSNVGFGNIGNANIGGANIGDFNVGIANTGPGLTAAVNNIGIGNTGNYNIGVGNTGNYNIGFGNT GNNNIGIGLSGDNQIGFGPLNAGIANMGLFNLGDNNFGMANAGNFNQGIANTGNNNIGLFNTGNNNVGIW LTGDGLSGFSSLNSGAGNTGFFNSGTANTGLFNSGTGNTGLFNSGTGNVGIGNMGTGGFGVGLSGDSQVG IGGTNSGSFNIGLFNSGTGNVGIGNSGTGNVGIGNTGTGNTGIGNSGNYNTGLLNAGLVNTGIANPGNHN TGLFNIGTFNTGIANPGHYNTGSYNTGSYNTGMANAGDYGTGAFITGSMNNGLLWRADRQGLLAANYTIT IERPAAFLNVDIPVNIPITGDITNVSIPAITFPRIDASGSVDIGILSGTVLAPVGPITLHGGDASAPLDT PIEIDFGPSPAINLNIGKPDGSTVINIVGGAGAGPISIPIIDLRPAPGFFNATTGPSSGFLNWGAGSASG LLNFGNNSGLYNFATSSMGNSGFQNYGSLQSGWANLGNSISGIYNTGLGAPANVSGLLNIGTNLAGWLQN GPTETTFSVGLANLGFWNLGSANIGNYNLGSANIGVYNLGSANIGDFNLGSANIGDFNLGSANIGSSNIG FGNVGPGLTAAIGNIGFGNTGNGNIGIGNTGTGNIGFGNTGNGNIGIGLTGDTMTGFGGWNSGTGNIGLF NSGTGNIGFGNSGTGNWGIGNSGDYNTGIGNTGSTNSGFFNTGLVNTGIGNSGDYNTGLFNAGNTNTGSF NPGDYNTGGFNPGNYNTGYFNPGNSNTGIANSGDVNTGAFNSGNYSNGFFWRGDYQGLGGFAYQSAVSEI PWSYDRFQH*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. tuberculosis H37Rv | Rv0355c | PPE8 | - | 100% (3300) | PPE FAMILY PROTEIN |
M. tuberculosis H37Rv | Rv0304c | PPE5 | 0.0 | 48.51% (2375) | PPE family protein |
M. tuberculosis H37Rv | Rv3350c | PPE56 | 0.0 | 38.64% (3367) | PPE family protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0362c | PPE8 | 0.0 | 99.76% (3296) | PPE family protein |
M. gilvum PYR-GCK | Mflv_5091 | - | 1e-23 | 31.70% (470) | triple helix repeat-containing collagen |
M. leprae Br4923 | MLBr_01182 | - | 5e-31 | 43.98% (166) | PPE-family protein |
M. abscessus ATCC 19977 | MAB_0669 | - | 2e-24 | 36.99% (173) | PPE-family protein |
M. marinum M | MMAR_0642 | - | 0.0 | 70.55% (3324) | PPE family protein |
M. avium 104 | MAV_4704 | - | 3e-54 | 56.16% (203) | PPE family protein |
M. smegmatis MC2 155 | MSMEG_0868 | - | 3e-36 | 26.55% (1100) | hypothetical protein MSMEG_0868 |
M. thermoresistible (build 8) | TH_3113 | - | 8e-29 | 41.54% (195) | PUTATIVE PPE protein |
M. ulcerans Agy99 | MUL_0965 | - | 0.0 | 48.02% (885) | PPE family protein |
M. vanbaalenii PYR-1 | Mvan_0415 | - | 4e-26 | 40.32% (186) | PPE protein |
CLUSTAL 2.0.9 multiple sequence alignment Rv0355c|M.tuberculosis_H37Rv -------------------------------------------------- Mb0362c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_0642|M.marinum_M -------------------------------------------------- MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES Rv0355c|M.tuberculosis_H37Rv -------------------------------------------------- Mb0362c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_0642|M.marinum_M -------------------------------------------------- MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT Rv0355c|M.tuberculosis_H37Rv -------------------------------------------------- Mb0362c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_0642|M.marinum_M -------------------------------------------------- MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA Rv0355c|M.tuberculosis_H37Rv -----------------------------------MS---FAVLPPEINS Mb0362c|M.bovis_AF2122/97 -----------------------------------MS---FAVLPPEINS MMAR_0642|M.marinum_M -----------------------------------MN---FAVLPPEINS MUL_0965|M.ulcerans_Agy99 -----------------------------------MN---FIMLPPEINS MAV_4704|M.avium_104 -----------------------------------MTNPHFAWLPPEVNS MLBr_01182|M.leprae_Br4923 -------------------------------------MFDFAALSPETNS MAB_0669|M.abscessus_ATCC_1997 -----------------------------------MTAPIWMAEPPEVHS Mvan_0415|M.vanbaalenii_PYR-1 -----------------------------------MSSPVWMALPPEVHS TH_3113|M.thermoresistible__bu -----------------------------------------MALPPEVHS Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP .. . Rv0355c|M.tuberculosis_H37Rv ARLY--------------------VGAGLAPMLDAAAAWDGLADELGSAA Mb0362c|M.bovis_AF2122/97 ARLY--------------------VGAGLAPMLDAAAAWDGLADELGSAA MMAR_0642|M.marinum_M ARLT--------------------IGAGLGPMLEAANAWQGLAGELGSAA MUL_0965|M.ulcerans_Agy99 ARIF--------------------AGAGVGPTLAAAAAWDALAADLASAA MAV_4704|M.avium_104 ALIY--------------------SGPGPGPLLAAAAAWDGLAEELASSA MLBr_01182|M.leprae_Br4923 TRMY--------------------LGPGSSPILTAAAAWVVLAKELTAAA MAB_0669|M.abscessus_ATCC_1997 ALLS--------------------AGPGPGAVLAAAVQWQEIGNNYANTA Mvan_0415|M.vanbaalenii_PYR-1 ALLS--------------------SGPGPGSMLAAAATWQSLSAEYAAAA TH_3113|M.thermoresistible__bu TLLR--------------------TGPGPGALSAAADAWRMLSDEYRAAA Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA : *. . : :. Rv0355c|M.tuberculosis_H37Rv AS----FSAVTAGLAGSSWLGAASTAMTGAAAPYLGWLSAAAAQAQQAAT Mb0362c|M.bovis_AF2122/97 AS----FSAVTAGLAGSSWLGAASTAMTGAAAPYLGWLSAAAAQAQQAAT MMAR_0642|M.marinum_M SA----FSSVTTDLVSGGWQGAASTAMASAAAPYLKWLTTAAAQAGQAAT MUL_0965|M.ulcerans_Agy99 QS----FAAITVGLVGEAWQGAAATAMAAAARPYASWLGTAAARAAVTAA MAV_4704|M.avium_104 QS----FSSVTSDLASGSWQGASSAAMMTVANQYVSWLSAAAAQAEEVSH MLBr_01182|M.leprae_Br4923 QG----LQSAVEALLT-TFEGESAAALAERVTPYEKWLTQNAASAELTAT MAB_0669|M.abscessus_ATCC_1997 VE----LAQVLAGVRAGSWQGPSASEYVAAHLPYLAWLEQAAAESSVIAA Mvan_0415|M.vanbaalenii_PYR-1 AE----LSSILADVQAGAWEGPSSEQYVAAHTPYLAWLAQQSAAGAAAAA TH_3113|M.thermoresistible__bu VE----LAAVVSQTCATAWEGVGADAYAAAHGPYLFWLTDTAAAAAAAGA Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNS-DVVGMDGGNGGNGGLFGGNGGNGGNGLG MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDG-SAAGLAGGNGGNAGLFG-NGGNGGVGWA : . : .. . Rv0355c|M.tuberculosis_H37Rv QTRLAAAAFEAALAATVHPAIISANRALFVSLVVSNLLGQNAPAIAATEA Mb0362c|M.bovis_AF2122/97 QTRLAAAAFEAALAATVHPAIISANRALFVSLVVSNLLGQNAPAIAATEA MMAR_0642|M.marinum_M QVRLAAAAFEAALAATVHPAAISANRSQFVSLVVSNLLGQNAPAIAAAEA MUL_0965|M.ulcerans_Agy99 QANAAAAVFEAAQAATAHPELVAANRNQLVSLVVSNLFGQNAPAIASTEA MAV_4704|M.avium_104 QASAIATAFEVALAATVQPAVVAANRALVQALAATNWLGQNTPAIADIEA MLBr_01182|M.leprae_Br4923 QLTVAANAYETAFTMTVPPLMVFVNRAQACLLIMSNIFGQNSTAIAEKEA MAB_0669|M.abscessus_ATCC_1997 QHETTAAAYNSALAAMPTLAELAANHITHGVLVGTNFFGINTIPIALNEA Mvan_0415|M.vanbaalenii_PYR-1 QHEAAAAAYSTALATMPTLPELALNHTTHAVLVATNFLGINTIPIAMTEA TH_3113|M.thermoresistible__bu QLEAAAAAHASALAAMPTMAELTANRTTHAALVATNFFGVNTIPIAVNEA Mflv_5091|M.gilvum_PYR-GCK GGNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGAT MSMEG_0868|M.smegmatis_MC2_155 GLDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGT . : : Rv0355c|M.tuberculosis_H37Rv AYEQMWAQDVAAMFGYHAGASAAVSALTPFGQALPTVAGGGALVSAAAAQ Mb0362c|M.bovis_AF2122/97 AYEQMWAQDVAAMFGYHAGASAAVSALTPFGQALPTVAGGGALVSAAAAQ MMAR_0642|M.marinum_M AYEQMWAQDVAAMFGYRSGAESIAAALTPF----PLQAAG---------- MUL_0965|M.ulcerans_Agy99 AYDQLWAQDVAAMAGYHSGASAVAAQLAPWQQALRTLQN----------- MAV_4704|M.avium_104 AYEQMWASDVAAMFGYHADASAAVAKLPPW-------------------- MLBr_01182|M.leprae_Br4923 EYTEMWIQDAAAMTSYQASVLEAVGATKAFT------------------- MAB_0669|M.abscessus_ATCC_1997 DYVRMWVQAAATMSAYQATTEAMTSAIPPTQQ------------------ Mvan_0415|M.vanbaalenii_PYR-1 DYVRMWIQAATTMATYQAVSGAALAATPTATP------------------ TH_3113|M.thermoresistible__bu DYARMWIQAATTMATYEAVASAAVSATPRTVA------------------ Mflv_5091|M.gilvum_PYR-GCK GVTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG-------------- MSMEG_0868|M.smegmatis_MC2_155 GGTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGF---------- . . Rv0355c|M.tuberculosis_H37Rv VTTRVFRNLGLANVGEGNVGNGNVGNFNLGSANIGNGNIGSGNIGSSNIG Mb0362c|M.bovis_AF2122/97 VTTRVFRNLGLANVGEGNVGNGNVGNFNLGSANIGNGNIGSGNIGSSNIG MMAR_0642|M.marinum_M --SVVTANLGFANVGFRNFGNGNVGDYNLGSGNLGSENVGSSNIGSGNIG MUL_0965|M.ulcerans_Agy99 ------------------------------------------RVAGATTA MAV_4704|M.avium_104 ------------------------------------------NEVLQNLG MLBr_01182|M.leprae_Br4923 ---------------------------------------------APPLG MAB_0669|M.abscessus_ATCC_1997 ------------------------------------------PPAILSPG Mvan_0415|M.vanbaalenii_PYR-1 ------------------------------------------APFVLAPG TH_3113|M.thermoresistible__bu ------------------------------------------PPPILGAG Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------AVG--S MSMEG_0868|M.smegmatis_MC2_155 ----------------------------------GYVLIAGPNVTVGSET Rv0355c|M.tuberculosis_H37Rv FGNVGPGLTAALNNIGFGNTGSNNIGFGNTGSNNIGFGNTGDGNRGIGLT Mb0362c|M.bovis_AF2122/97 FGNVGPGLTAALNNIGFGNTGSNNIGFGNTGSNNIGFGNTGDGNRGIGLT MMAR_0642|M.marinum_M FGNSGPALTAALNNIGFGNTGSNNIGFGNTGNNNIGFGNTGDNNRGIGLT MUL_0965|M.ulcerans_Agy99 LPPPGPAAAAALP------------------------------------- MAV_4704|M.avium_104 FSNASTAVTRPAG------------------------------------S MLBr_01182|M.leprae_Br4923 VNEVGLAQEVVEEV------------------------------------ MAB_0669|M.abscessus_ATCC_1997 -GEARSDQSDVPGS------------------------------------ Mvan_0415|M.vanbaalenii_PYR-1 VGEAGRAAADVTAF------------------------------------ TH_3113|M.thermoresistible__bu TGESATAAITGAHV------------------------------------ Mflv_5091|M.gilvum_PYR-GCK AGAAGEAGETGTWG------------------------------------ MSMEG_0868|M.smegmatis_MC2_155 RGGTGGAGGTGGQS------------------------------------ Rv0355c|M.tuberculosis_H37Rv GSGLLGFGGLNSGTGNIGLFNSGTGNVGIGNSGTGNWGIGNSGNSYNTGF Mb0362c|M.bovis_AF2122/97 GSGLLGFGGLNSGTGNIGLFNSGTGNVGIGNSGTGNWGIGNSGNSYNTGF MMAR_0642|M.marinum_M GTGQFGLGGLNSGSGNIGLFNSGTGNFGIGNSGTGNWGIGNSGNSYNTGI MUL_0965|M.ulcerans_Agy99 GAAAVGFPVLHIG------------------------------------- MAV_4704|M.avium_104 GAVARGY------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- Rv0355c|M.tuberculosis_H37Rv GNSGDANTGFFNSGIANTGVGNAGNYNTGSYNPGNSNTGGFNMGQYNTGY Mb0362c|M.bovis_AF2122/97 GNSGDANTGFFNSGIANTGVGNAGNYNTGSYNPGNSNTGGFNMGQYNTGY MMAR_0642|M.marinum_M GNSGDANTGFFNAGVANTGIGNVGSYNTGGFNPGDANTGGFNTGSYNTGY MUL_0965|M.ulcerans_Agy99 -----------NIGFANLSVGNIGDYN----------------------- MAV_4704|M.avium_104 -----------TSRIAGFLAPRAPQ------------------------- MLBr_01182|M.leprae_Br4923 -----------VEEVVEEVVEAEQAIS----------------------- MAB_0669|M.abscessus_ATCC_1997 -----------PDQIMKMLQG----------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -----------AAQAQAAEAGSALDLSNIIADLIRA-------------- TH_3113|M.thermoresistible__bu -----------TAELRAAESRTLLDEINELIDRLFAPL------------ Mflv_5091|M.gilvum_PYR-GCK -----------NAGLPGKAGDAGGAG----AVGAAG-------------- MSMEG_0868|M.smegmatis_MC2_155 -----------TAAGPGKGGGGGGGGGGAILIGANGGT------------ Rv0355c|M.tuberculosis_H37Rv LNSGNYNTGLANSGNVNTGAFITGNFNNGFLWRGDHQGLIFGSPGFFNST Mb0362c|M.bovis_AF2122/97 LNSGNYNTGLANSGNVNTGAFITGNFNNGFLWRGDHQGLIFGSPGFFNST MMAR_0642|M.marinum_M LNRGDYNTGVANFGNVNTGALNTGDYNNGFLWRGDNQGLIFGEPGFGNST MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- Rv0355c|M.tuberculosis_H37Rv SAPSSGFFNSGAGSASGFLNSGANNSGFFNSSSGAIGNSGLANAGVLVSG Mb0362c|M.bovis_AF2122/97 SAPSSGFFNSGAGSASGFLNSGANNSGFFNSSSGAIGNSGLANAGVLVSG MMAR_0642|M.marinum_M TVPSSGFFNSGEGSASGFFNSGANNSGFFNDSSGPIGNSGFANTGVLQSG MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- Rv0355c|M.tuberculosis_H37Rv VINSGNTVSGLFNMSLVAITTPALISGFFNTGSNMSGFFGGPPVFNLGLA Mb0362c|M.bovis_AF2122/97 VINSGNTVSGLFNMSLVAITTPALISGFFNTGSNMSGFFGGPPVFNLGLA MMAR_0642|M.marinum_M LVNSGNTISGLLNSSLVPITTPAYISGVLNTGSNLAGFLLGPTLFNIGFA MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- Rv0355c|M.tuberculosis_H37Rv NRGVVNILGNANIGNYNILGSGNVGDFNILGSGNLGSQNILGSGNVGSFN Mb0362c|M.bovis_AF2122/97 NRGVVNILGNANIGNYNILGSGNVGDFNILGSGNLGSQNILGSGNVGSFN MMAR_0642|M.marinum_M NDGVGNILAHANVGNYNIGGNGNVGDYNIFGSGNAGSYNIFGSGNIGSLN MUL_0965|M.ulcerans_Agy99 ----------------------------------------LGSGNTGSFN MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- Rv0355c|M.tuberculosis_H37Rv IGSG----------NIGVFNVGSGSLGNYNIGSGNLGIYNIGFGNVGDYN Mb0362c|M.bovis_AF2122/97 IGSG----------NIGVFNVGSGSLGNYNIGSGNLGIYNIGFGNVGDYN MMAR_0642|M.marinum_M LGSGNFGGTNFGSGNIGSLNLGSANIGSYNIGSASLGSYNVGFGNLGDYN MUL_0965|M.ulcerans_Agy99 LGSG-------------------------NIGDASLGS-----GNAGDSN MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 ---------------------------FQQWFEKMG--FNPATSAVLAVI Mvan_0415|M.vanbaalenii_PYR-1 -----------------------YGELLRFLFEPIFDFLRDPLGNTIKLI TH_3113|M.thermoresistible__bu --------------FPPGFADALPDGLLGTLLAPLLP-GATGDGPPMATI Mflv_5091|M.gilvum_PYR-GCK ---------------------------AAGTVGTAGATGGTG----TGAN MSMEG_0868|M.smegmatis_MC2_155 --------------------------VDGHAIGGNGGNGGNGSTTAAGGN Rv0355c|M.tuberculosis_H37Rv VGFGNAGDFNQGFANTGNNNIGFANTGNNNIGIGLSGDNQQGFNIASGWN Mb0362c|M.bovis_AF2122/97 VGFGNAGDFNQGFANTGNNNIGFANTGNNNIGIGLSGDNQQGFNIASGWN MMAR_0642|M.marinum_M TGFGNAGSYNQGLANTGSNNAGFANTGNGNIGIGLTGDGQIGIGALN--- MUL_0965|M.ulcerans_Agy99 VGFG----------NFGSNNVGIGNNGNNNIGIGLNGDDLIGIGALN--- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 ---------------QAALDQAVNEGMEATVVPQVDQQVNVDVATPQTAV MAB_0669|M.abscessus_ATCC_1997 MLFLYD-----LLWYPYYAS-------------------------YLLPF Mvan_0415|M.vanbaalenii_PYR-1 TDFLTNPAQALITWGPFLAAVAYQ-------AVSWVGASILYPSLLLLPL TH_3113|M.thermoresistible__bu MSFLLMGLSNPAYLFPVLVYLLFTGVVHTTVAVSGMLAQLVPLMPALLPV Mflv_5091|M.gilvum_PYR-GCK GGAGGVG-----GVGGTGAAGAAGGAG------GLGETGTTG-------- MSMEG_0868|M.smegmatis_MC2_155 GGTGGTGRVIAEGTGSTAEGTATGGDGGHSTGTGIGGNGGIGSVYAYGNN Rv0355c|M.tuberculosis_H37Rv SGTGNSGLFNSGTNNVGIFNAGTGNVGIANSGTG----------NWGIGN Mb0362c|M.bovis_AF2122/97 SGTGNSGLFNSGTNNVGIFNAGTGNVGIANSGTG----------NWGIGN MMAR_0642|M.marinum_M SGIGNAGLFNSGTDNVGLFNSGSGNIGIGNSGSGNTGLLNAGVANWGLEN MUL_0965|M.ulcerans_Agy99 SGAGNLGFGNSGTNNIGFFNSGDNNIGFFNSGSG---------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 PDSSSAAAPQLWGGFAQHLSPINDTLSMINNHAG---------------- MAB_0669|M.abscessus_ATCC_1997 LIPALSGLSGL-AALMHLR-PAAPGPVPAAALSP---------------- Mvan_0415|M.vanbaalenii_PYR-1 VATTLAIVLGVGAYLLENL-PAPAEDAPAEEPAA---------------- TH_3113|M.thermoresistible__bu AVAALGGLAGVWAGLSGLAGLAGLTAVPAADGGA---------------- Mflv_5091|M.gilvum_PYR-GCK ------GAGGVGGQGTAGGTGGVGGIG----------------------- MSMEG_0868|M.smegmatis_MC2_155 GAVSGTATGGRGGDGIDGGTGGAGGMGEIYSGAD---------------- Rv0355c|M.tuberculosis_H37Rv PGTDNTGILNAGSYNTGILNAGDFNTGFYNTGSYNTGGFNVGNTNTGNFN Mb0362c|M.bovis_AF2122/97 PGTDNTGILNAGSYNTGILNAGDFNTGFYNTGSYNTGGFNVGNTNTGNFN MMAR_0642|M.marinum_M PGTANTGIGNAGQYNTGLHNVGAANTGFYNNGSYNTGGFNVGSTNTGSFD MUL_0965|M.ulcerans_Agy99 --------------NFGFENAGDINTGFWNGR------------------ MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- Rv0355c|M.tuberculosis_H37Rv VGDTNTGSYNPGDTNTGFFNPGNVNTGAFDTGDFNNGFLVAGDNQGQIAI Mb0362c|M.bovis_AF2122/97 VGDTNTGSYNPGDTNTGFFNPGNVNTGAFDTGDFNNGFLVAGDNQGQIAI MMAR_0642|M.marinum_M AGSANTGNFNPGDTNTGSYNPGNVNTGFFDTGNYNNGFFVTSDNQGQIAI MUL_0965|M.ulcerans_Agy99 ------------DTNTG--------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- Rv0355c|M.tuberculosis_H37Rv DLSVTTPFIPINEQMVIDVHNVMTFGGNMITVTEASTVFPQTFYLSGLFF Mb0362c|M.bovis_AF2122/97 DLSVTTPFIPINEQMVIDVHNVMTFGGNMITVTEASTVFPQTFYLSGLFF MMAR_0642|M.marinum_M NLSVTTPHIPIDVQSIVPVNQVYTLGGNTIQVSEAGSVFPRTYYLGGLFF MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- Rv0355c|M.tuberculosis_H37Rv FGPVNLSASTLTVPTITLTIGGPTVTVPISIVGALESRTITFLKIDPAPG Mb0362c|M.bovis_AF2122/97 FGPVNLSASTLTVPTITLTIGGPTVTVPISIVGALESRTITFLKIDPAPG MMAR_0642|M.marinum_M LGPINLGASTLTIPTVTIALGGPSTNIPISIVGAVESRTITFLDIPAAPG MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- Rv0355c|M.tuberculosis_H37Rv IGNSTTNPSSGFFNSGTGGTSGFQNVGGGSSGVWNSGLSSAIGNSGFQNL Mb0362c|M.bovis_AF2122/97 IGNSTTNPSSGFFNSGTGGTSGFQNVGGGSSGVWNSGLSSAIGNSGFQNL MMAR_0642|M.marinum_M FGNTTAGPSSGFFNAGTGGNSGFANFGAASSGLWNSGVA-AAGNSGVQNF MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- Rv0355c|M.tuberculosis_H37Rv GSLQSGWANLGNSVSGFFNTSTVNLSTPANVSGLNNIGTNLSGVFRGPTG Mb0362c|M.bovis_AF2122/97 GSLQSGWANLGNSVSGFFNTSTVNLSTPANVSGLNNIGTNLSGVFRGPTG MMAR_0642|M.marinum_M GSLASGWANLGNTLSGFYNTSTANLAAPANLSGLFNVGTDLAGVLRDANG MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- Rv0355c|M.tuberculosis_H37Rv TIFNAGLANLGQLNIGSANLGDFNLGSGNVGSFNVFSGNQGSYNIGPANL Mb0362c|M.bovis_AF2122/97 TIFNAGLANLGQLNIGSANLGDFNLGSGNVGSFNVFSGNQGSYNIGPANL MMAR_0642|M.marinum_M TILNLGLADLGHLNVGSGNVGDFNVGSANIGSANFGFGNVGSDNLGSGNI MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- Rv0355c|M.tuberculosis_H37Rv GNYNIGFANLGN------YNIGFGNAGDFNQGFANTGNNNIGFANTGNNN Mb0362c|M.bovis_AF2122/97 GNYNIGFANLGN------YNIGFGNAGDFNQGFANTGNNNIGFANTGNNN MMAR_0642|M.marinum_M GSGNIGFGNAGARLTDAFNNIGFGNTGDNNIGFGNTGNGNFGFGNTGNGN MUL_0965|M.ulcerans_Agy99 --------------------------------FGNSGLSNFGFG------ MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- Rv0355c|M.tuberculosis_H37Rv IGIGLSGDNQQGFNFAGGWNSGTANIGLFNSGTNNVGIGNSGTGNWGIGN Mb0362c|M.bovis_AF2122/97 IGIGLSGDNQQGFNFAGGWNSGTANIGLFNSGTNNVGIGNSGTGNWGIGN MMAR_0642|M.marinum_M IGIGLTGAGQRGVNFAGGLNSGSGNIGLFNSGTNNVGIGNSGTGNWGIGN MUL_0965|M.ulcerans_Agy99 -----------------------------NSGVNNVGAGNGGSSNVGLGN MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- Rv0355c|M.tuberculosis_H37Rv SGSGNTGIGNTGSTNTGFFNTGIVNTGVANAGSYNTGWYNTGDTNTGIAN Mb0362c|M.bovis_AF2122/97 SGSGNTGIGNTGSTNTGFFNTGIVNTGVANAGSYNTGWYNTGDTNTGIAN MMAR_0642|M.marinum_M SGSLNTGFGNAGSTNTGLFNTGMVNTGIANVGDYNTGWFNTGDVNTGAAN MUL_0965|M.ulcerans_Agy99 AG-------------------------LLNTGSFNSGKFNTGDFNS---- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- Rv0355c|M.tuberculosis_H37Rv LGDFNTGFYNTGNFSTGFANQGDIATGAFITGDMGNGAFWRGDQQGLFSA Mb0362c|M.bovis_AF2122/97 LGDFNTGFYNTGNFSTGFANQGDIATGAFITGDMGNGAFWRGDQQGLFSA MMAR_0642|M.marinum_M RGDYNTGWYNTGNYSTGFANAGNIDTGLLISGDMGNGFAWRGDQQGQVSA MUL_0965|M.ulcerans_Agy99 -GSMNTGYFNSSGHNTGLGNSG---------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- Rv0355c|M.tuberculosis_H37Rv GYRVHVPEIPAHVTVEVPVNIPITASFTNTVYSGITLEQINFGFTIDIAG Mb0362c|M.bovis_AF2122/97 GYRVHVPEIPAHVTVEVPVNIPITASFTNTVYSGITLEQINFGFTIDIAG MMAR_0642|M.marinum_M SYVIHVPEIPAHVDASAPINIPLTANFTNTLYSGITMEDINFGFTVAIGP MUL_0965|M.ulcerans_Agy99 --------------------------FTN--------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- Rv0355c|M.tuberculosis_H37Rv IPLLAGAISKAVLPPITGTGPAITVNIGDPGGSTAIRIPATASVGPFDVT Mb0362c|M.bovis_AF2122/97 IPLLAGAISKAVLPPITGTGPAITVNIGDPGGSTAIRIPATASVGPFDVT MMAR_0642|M.marinum_M LPVLTGTIDSVTLAPITATGPAISFNIGDPKGTTVVSIPATASLGPVDWT MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- Rv0355c|M.tuberculosis_H37Rv FVNIAATTGFFNATTDPSSGFFNGGPGTVSGIANIGANISGFQNVANSAT Mb0362c|M.bovis_AF2122/97 FVNIAATTGFFNATTDPSSGFFNGGPGTVSGIANIGANISGFQNVANSAT MMAR_0642|M.marinum_M IFDIPAVTGLFNSTSSPSSGFFNGGTGTVSGIANFGGDISGFQNFGTSAL MUL_0965|M.ulcerans_Agy99 ------------------TGFFN--------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- Rv0355c|M.tuberculosis_H37Rv SGFNNYGSLQSGLANLGDTVSGVFNTGIGAPANVSGMFNIGSNLAGFFHD Mb0362c|M.bovis_AF2122/97 SGFNNYGSLQSGLANLGDTVSGVFNTGIGAPANVSGMFNIGSNLAGFFHD MMAR_0642|M.marinum_M SGFKNVGSLQSGLLNIGDTVSGLFNTGIGTPANVSGVSNIGTTLAGIFVD MUL_0965|M.ulcerans_Agy99 --------------------SGDLNTGMGSPEDQS--------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- Rv0355c|M.tuberculosis_H37Rv QATGMSMFNLGLGNIGQFNVGFSNVGDSNAGLANIGSFNLGSGNLGSFNV Mb0362c|M.bovis_AF2122/97 QATGMSMFNLGLGNIGQFNVGFSNVGDSNAGLANIGSFNLGSGNLGSFNV MMAR_0642|M.marinum_M QASGMSTFSLGLADIGQANVGFGNTGDFNLGFANLGDENLGLGNSGFNNL MUL_0965|M.ulcerans_Agy99 -------------------------------VANSGFRNAGSGNS----- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- Rv0355c|M.tuberculosis_H37Rv FGGNQGSYNIGPANLGNYNIGLGNLGSYNFGFGNAGDFNLGFANTGNNNI Mb0362c|M.bovis_AF2122/97 FGGNQGSYNIGPANLGNYNIGLGNLGSYNFGFGNAGDFNLGFANTGNNNI MMAR_0642|M.marinum_M GLANLGNFNVGSANLGGYNIGSSNLGDYNVGFGNAGGFNQGLANSGNNNI MUL_0965|M.ulcerans_Agy99 ------------------------------GFNNTGSFSSGFFNSTNSNS MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- Rv0355c|M.tuberculosis_H37Rv GFANTGNNNIGIGLSGDNQQGFNFAGGWNSGSGNSGLFNSGTNNIGLFNS Mb0362c|M.bovis_AF2122/97 GFANTGNNNIGIGLSGDNQQGFNFAGGWNSGSGNSGLFNSGTNNIGLFNS MMAR_0642|M.marinum_M GLFNTGNNNIGIGLTGDNQQGFNFGGGLNSGTGNTGLFNSGTNNTGIFNS MUL_0965|M.ulcerans_Agy99 EFLNAG-------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK --------------------------------GAGSTGAVGG-------- MSMEG_0868|M.smegmatis_MC2_155 ----------------GEATGISAGGDGGSATGADSLGGRGGTSWVQAGY Rv0355c|M.tuberculosis_H37Rv GTGNIGIGNSGTGNWGIANTGDTNTGIFNTGDVNTGLLNAGNVNTGIFNT Mb0362c|M.bovis_AF2122/97 GTGNIGIGNSGTGNWGIANTGDTNTGIFNTGDVNTGLLNAGNVNTGIFNT MMAR_0642|M.marinum_M GTNNTGIFNSGNANWGIGNTGVTNTGVFNSGQINTGLWNAGNVNTGIGNP MUL_0965|M.ulcerans_Agy99 GTVNSGINNSGNTNAGIGNLGDDNFGLFNNG------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -MANAGLSLVNGMGSAMKSLAPTTT------------------------- MAB_0669|M.abscessus_ATCC_1997 GDRPIRRPTQHVEPNLAALPLPTSSVVPSGGS------------------ Mvan_0415|M.vanbaalenii_PYR-1 SSPAPTRADQPSPAIAVSAPPPPSSAAATVG------------------- TH_3113|M.thermoresistible__bu SAAPVPAGGPSLPSGSSAPPAPTGSAAPTTG------------------- Mflv_5091|M.gilvum_PYR-GCK ---VGGKGIQGGQGLQGGKGGDGGAGGKGGDADSMGS------------- MSMEG_0868|M.smegmatis_MC2_155 GPTTGGKASGTAKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIG Rv0355c|M.tuberculosis_H37Rv GHYNTGSFNAGSFNTAGFNPGSYNTGYLNTGSYNTGLANSGDVNTGGFIT Mb0362c|M.bovis_AF2122/97 GHYNTGSFNAGSFNTAGFNPGSYNTGYLNTGSYNTGLANSGDVNTGGFIT MMAR_0642|M.marinum_M GNYNTGSFNTGSFNTAGLNPGDYNTGYLNSGNYNTGFANSGDVNTGAFIS MUL_0965|M.ulcerans_Agy99 ------TFNTGAGNSSGGAVFPYTSGLFNSGNGSSGVFNAGDEQS----- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 ------KAAESAFKAMGSAVQSTGRGLLGSSSGGHVTAQLG--------- MAB_0669|M.abscessus_ATCC_1997 ----SVPVSTPTAPAHTVSSVPAPSAAISYAIPG---------------- Mvan_0415|M.vanbaalenii_PYR-1 ------TVATGTAPAPGAP-AAATASFVPYAVAG---------------- TH_3113|M.thermoresistible__bu ----TAPGGAGSPPPAGHSVPPAPHSAPPVGTSGP--------------- Mflv_5091|M.gilvum_PYR-GCK -----AGATGGKGGNGGNGGRGGLFG---------------KGGNAGNG- MSMEG_0868|M.smegmatis_MC2_155 GNGGAASANGAVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGG Rv0355c|M.tuberculosis_H37Rv GNYSNGFWWRGDYQGLAGISQTITVPDTAVPVKLHVPIFLDIPVTGTLGT Mb0362c|M.bovis_AF2122/97 GNYSNGFWWRGDYQGLAGISQTITVPDTAVPVKLHVPIFLDIPVTGTLGT MMAR_0642|M.marinum_M GNYSNGLLWRGDYQGLWGIDYAITIPDTAIPLNLDVPVYLDIPITGTLGV MUL_0965|M.ulcerans_Agy99 ------------------------------------------------GF MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 NGWVQ--------------------------------------------- Rv0355c|M.tuberculosis_H37Rv FTVHGFRFPEITGDIFLIGIPFNAATLDAFSFPNISIVLPNIGINLGSGP Mb0362c|M.bovis_AF2122/97 FTVHGFRFPEITGDIFLIGIPFNAATLDAFSFPNISIVLPNIGINLGSGP MMAR_0642|M.marinum_M FTVDGFTIPASTVELDIVGIGFKAVHVSAIKFPNLELGLPAIDINIGTGP MUL_0965|M.ulcerans_Agy99 FGTSGLVL---------------------------------------TGT MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- Rv0355c|M.tuberculosis_H37Rv DPLIDIAGTGGLLPIKIPLIDIPAAPGFGNSTTTPSSGFFNAGTGTVSGV Mb0362c|M.bovis_AF2122/97 DPLIDIAGTGGLLPIKIPLIDIPAAPGFGNSTTTPSSGFFNAGTGTVSGV MMAR_0642|M.marinum_M EPLIHIVGTGGLLPIKIPIIDIAAAPGFGNSTTTASSGFFNTGSGTASGF MUL_0965|M.ulcerans_Agy99 DGLAATTTSG------LPALDLPAP------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- Rv0355c|M.tuberculosis_H37Rv GNVGSNSSGFFNLTSGSSGISGVQNFGELISGGFNFGNTVSGLVNASTLG Mb0362c|M.bovis_AF2122/97 GNVGSNSSGFFDLTSGSSGISGVQNFGELISGGFNFGNTVSGLVNASTLG MMAR_0642|M.marinum_M GNTGGNNSGFFNLASGSSGISGYQNLGDLVSGMSNLGNSVSGFFNTSSLG MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- Rv0355c|M.tuberculosis_H37Rv LSMPANLSGGGNVGATVAGFVNNTQILNLGFGNVGSGNVGHGNIGDSNVG Mb0362c|M.bovis_AF2122/97 LSMPANLSGGGNVGATVAGFVNNTQILNLGFGNVGSGNVGHGNIGDSNVG MMAR_0642|M.marinum_M VSIPADISGAANIGTNIAGFFNDNPIGNLGIANLGNGNIGDGNIGSNNAG MUL_0965|M.ulcerans_Agy99 ---------------------------NLGIGNAGVGNLGLGNIGDYNLG MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 ---------------------------------------RAASIGSLRVP MAB_0669|M.abscessus_ATCC_1997 ----------------------------LVPPGVSFGPKSTEKSSESAVD Mvan_0415|M.vanbaalenii_PYR-1 ----------------------------RDP-GTGFSPTVRDSTSAKAPA TH_3113|M.thermoresistible__bu ------------------------PYLIAAQPAPGVARRSAGARRAASIV Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------ADGGTGGAGG MSMEG_0868|M.smegmatis_MC2_155 ------------------------AYDPNGPAGTTIDKGKAAGGNGGDGG Rv0355c|M.tuberculosis_H37Rv LGNLGNANVGHGNIGSFNVFSGNRGSYNIGPANLGNYNIGLGNLGSYNFG Mb0362c|M.bovis_AF2122/97 LGNLGNANVGHGNIGSFNVFSGNRGSYNIGPANLGNYNIGLGNLGSYNFG MMAR_0642|M.marinum_M FGNVGANNFGSGNIGSFNFLSGNHGTYNFGLGNLGDYNVGLANLGDYNVG MUL_0965|M.ulcerans_Agy99 SGNTGDANFGSGNIGALNLGSGNHG------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 QTWTTASQPVTAATRALSPAR----------------------------- MAB_0669|M.abscessus_ATCC_1997 TVAAVAAARGAVAAQARRRLRGKNK------------------------- Mvan_0415|M.vanbaalenii_PYR-1 SGIPAAASGVAASAAERRKRRRRQK------------------------- TH_3113|M.thermoresistible__bu EPAGSAAAAAAARESAPIRRRRGQK------------------------- Mflv_5091|M.gilvum_PYR-GCK AGGTGG-TGGAGGTGG---------------------------------- MSMEG_0868|M.smegmatis_MC2_155 FNGTGGATGGRGGDGAGASVWKANGQHS---------------------- Rv0355c|M.tuberculosis_H37Rv FGNAGDFNLGFANSGSNNIGFANTGNNNIGIGLSGHNQQGF---GSWNSG Mb0362c|M.bovis_AF2122/97 FGNAGDFNLGFANSGSNNIGFANTGNNNIGIGLSGHNQQGF---GSWNSG MMAR_0642|M.marinum_M FGNAGSLNQGFANTGDHNIGIGNTGNNNIGIGLTGDNQVGINLAGGLNSG MUL_0965|M.ulcerans_Agy99 ---------------DANLGFGNTGDNNIG-------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- Rv0355c|M.tuberculosis_H37Rv TANTGLFNSGTNNIGLFNSGTGNIGIGNSGIGNTGIGNPGVGNTGLGNSG Mb0362c|M.bovis_AF2122/97 TANTGLFNSGTNNIGLFNSGTGNIGIGNSGIGNTGIGNPGVGNTGLGNSG MMAR_0642|M.marinum_M TGNAGLFNSGTNNTGIFNSGTGNTGIFNSGTANWGIGNSGTANSGIANSG MUL_0965|M.ulcerans_Agy99 -----LFNSGDNNVGFFNSGGANFGLANSGDTNTGLWNAGSTNTGFGNAG MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 ----VAVATESESAPLLGGGLPMAPMVPGGGS-----GTGGVNTALRLQP MAB_0669|M.abscessus_ATCC_1997 ------AEAGGRRHEYLEETAGMG-----ATATADVPAYAATGRGTGPLG Mvan_0415|M.vanbaalenii_PYR-1 ------DEIAGR--AYADAYADYEPEPDDEPPVRQEPRIAATERGAGPMG TH_3113|M.thermoresistible__bu ------DGLHGHRHEHQQPASMSAATAPSAAGIRVLGGAGRISRTRGSVP Mflv_5091|M.gilvum_PYR-GCK --------TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTG MSMEG_0868|M.smegmatis_MC2_155 ---TGQTDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHG Rv0355c|M.tuberculosis_H37Rv TGNWGLWNPGTGNMGVANVGTYNTGGYNVGSTNTGIANVGIANTGSYNTG Mb0362c|M.bovis_AF2122/97 TGNWGLWNPGTGNMGVANVGTYNTGGYNVGSTNTGIANVGIANTGSYNTG MMAR_0642|M.marinum_M STNWGLWNPGTGNTGIANAGDYNTGLYNAGHTNTGLANPTDYNTGFFNTG MUL_0965|M.ulcerans_Agy99 SADFGFGNAGDRNMGFG----------NAGAANMGAGNSGSYNTGSFNSG MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 RAFVMPRNPAAG-------------------------------------- MAB_0669|M.abscessus_ATCC_1997 FAGTAPAAASTHVAATVRLSSD--EARQVIPMLPSTWDAD---------- Mvan_0415|M.vanbaalenii_PYR-1 FAGTVSRDAAQAGGLTT-LPGDPFGGGPKAPMLPGTWDPDTEPDERHNHH TH_3113|M.thermoresistible__bu HAEITPGDPTEPSSPTD---------RAHRPAEPN--------------- Mflv_5091|M.gilvum_PYR-GCK GTGGKGGTGGTGGAGGTG----GDGGTGGTGGTGGTG---------GTGG MSMEG_0868|M.smegmatis_MC2_155 GDGGRGGDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGG Rv0355c|M.tuberculosis_H37Rv STNTGSFNDGDFNTGFYNTGDYNTGFYNTGDVNTGAFIGGNFSNGAFWQS Mb0362c|M.bovis_AF2122/97 STNTGSFNDGDFNTGFYNTGDYNTGFYNTGDVNTGAFIGGNFSNGAFWQS MMAR_0642|M.marinum_M DYNTGLANAGNYNTGFFNTGDYNTGLANTGDVNTGAFISGNYSNGMFWRG MUL_0965|M.ulcerans_Agy99 TLNTGDFNGGDHNTGWGNSGNTNTGGINSGDLNT---------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -GGDQN-------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 DGKDSQ-------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK TGGTGGAG-----------DGTGGTGGTGG-------------------- MSMEG_0868|M.smegmatis_MC2_155 NGGNGGAGRIRVNNGTATGTATGGNGGNGGNG------------------ Rv0355c|M.tuberculosis_H37Rv DHQGQWGAHYAITVPQIPLLNFSLNIPVNIPIHLDFGTLAVNGFQIPAIT Mb0362c|M.bovis_AF2122/97 DHQGQWGAHYAITVPQIPLLNFSLNIPVNIPIHLDFGTLAVNGFQIPAIT MMAR_0642|M.marinum_M DYQGLVGAHYEIFIPEFPVLNFDLNIPVDIPIYLDLGSLALNGFTIPTIT MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- Rv0355c|M.tuberculosis_H37Rv LRALGVTHFSVGPIIVPRIAGTLPVIDINIGDPGGSSSIPITITSGAGPV Mb0362c|M.bovis_AF2122/97 LRALGVTHFSVGPIIVPRIAGTLPVIDINIGDPGGSSSIPITITSGAGPV MMAR_0642|M.marinum_M IDALSITDFKIGPITIPTIKGILPVIDINIGNPDGSSSIPIAIRSGLGPI MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- Rv0355c|M.tuberculosis_H37Rv VIPLLDIPPAPGFGNSTTGPSSGFFNSGTGSSSGFGNVGANNSGFWNTAF Mb0362c|M.bovis_AF2122/97 VIPLLDIPPAPGFGNSTTGPSSGFFNSGTGSSSGFGNVGANNSGFWNTAF MMAR_0642|M.marinum_M SIVLLDIPAAPGFGNSTSAPSSGFFNSGTGTASGFGNVGANNSGFWNTGF MUL_0965|M.ulcerans_Agy99 -----------GFGSSADQAVT---------NSGFGNNGSGNSGFN---- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -----TGGQGGQGGQGG-----------------TGGTGGQGG-LGGGGG MSMEG_0868|M.smegmatis_MC2_155 ---DADGHRGGKGGDGGEALIRATVIGSNASGTATGGDGGNGGTLGATNG Rv0355c|M.tuberculosis_H37Rv AGIGNSGLQNFGSLQSGWANLGNTVSGFYNTSAADFATPANLSGLSNVGA Mb0362c|M.bovis_AF2122/97 AGIGNSGLQNFGSLQSGWANLGNTVSGFYNTSAADFATPANLSGLSNVGA MMAR_0642|M.marinum_M GDIGSSGLQNYGQQLSGWANLGNTVSGWYNSSTADLPTAANLSGFFNIGT MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK TG-----------------------GQGGTGGTGGQGGTGGTGGTGGTG- MSMEG_0868|M.smegmatis_MC2_155 TGGAATIVAYNVVQANPQASGTATDGHGGSGINGGHGGNGGQGTIEANGP Rv0355c|M.tuberculosis_H37Rv DLTGVLRGPNGSTFNAGLANLGQFNVGSANLGSANLGSANLGSANLGNSN Mb0362c|M.bovis_AF2122/97 DLTGVLRGPNGSTFNAGLANLGQFNVG-----SANLGSANLGSANLGNSN MMAR_0642|M.marinum_M ELSGVLRDSAGTIFNAGLGDLGQLNLG-----SGNVGDFNVGSANIGSFN MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------GTGGAGGDGGLGGLGGFGGSGGTGGQGGLGGPGGSTGGAGGAG MSMEG_0868|M.smegmatis_MC2_155 SAVASGIGAGGNGGDGIDGGLGGNGGDGVVNTTANAANPGSATGTATGGD Rv0355c|M.tuberculosis_H37Rv VGFGNIGNANIGGANIGDFNVGIANTGPGLTAAVNNIGIGNTGNYNIGVG Mb0362c|M.bovis_AF2122/97 VGFGNIGNANIGGANIGDFNVGIANTGPGLTAAVNNIGIGNTGNYNIGVG MMAR_0642|M.marinum_M VGFGNVGADNLGSGNIGSGNIGFGNAGAGLTEAFNNIGFGNVGDTNIGFG MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK G--QAGTAGKGGLFG----GSGSAGKAGATGAAGASGGKGAQGATGAQGA MSMEG_0868|M.smegmatis_MC2_155 GGKATGTASQGGNGGPSWVQSGYGSTLGGNATGTATAGKGGEASNGGVAG Rv0355c|M.tuberculosis_H37Rv NTGNYNIGFGNTGNNNIGIGLSGDNQIGFGPLNAGIANMGLFNLGDNNFG Mb0362c|M.bovis_AF2122/97 NTGNYNIGFGNTGNNNIGIGLSGDNQIGFGPLNAGIANMGLFNLGDNNFG MMAR_0642|M.marinum_M NTGNGNLGFGNTGNGNIGIGLSGDGQIGFGPLNDGVGNAGLFNLGDFNTG MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK TG------AQGATG-ATGAAGKAGATGAAGAAGAAGSAG----------- MSMEG_0868|M.smegmatis_MC2_155 NGGNALVMAAGTTGVATGNTATGGDGGAATTAGATGGAGGFSNIAAIHGA Rv0355c|M.tuberculosis_H37Rv MANAGNFNQGIANTGNNNIGLFNTGNNNVGIWLTGDGLSGFSSLNSGAGN Mb0362c|M.bovis_AF2122/97 MANAGNFNQGIANTGNNNIGLFNTGNNNVGIGLTGDGLSGFSSLNSGAGN MMAR_0642|M.marinum_M LANAGNDNQGWSNTGNNNIGLFNTGDNNVGIGLTGDGRVGFGSLSSGAGN MUL_0965|M.ulcerans_Agy99 --------------------------------------------NTGDTN MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK TTGAQGSAGTNGA-NGANGSQGAAGKAGATGTTGATG--------AAGED MSMEG_0868|M.smegmatis_MC2_155 ITDSTAISGHGGAGNGGNGGKGADGWVQAYDPAGPVGSKIANSSAVAGNG Rv0355c|M.tuberculosis_H37Rv TGFFNSGTANTGLFNSGTGNTGLFNSGTGNVGIGNMGTGGFGVGLSGDSQ Mb0362c|M.bovis_AF2122/97 TGFFNSGTANTGLFNSGTGNTGLFNSGTGNVGIGNMGTGGFGVGLSGDSQ MMAR_0642|M.marinum_M TGFFNSGTSNAGMFNSGTGNVGFFNSGTGNVGIGNMGTGGIGIGLQGDNL MUL_0965|M.ulcerans_Agy99 SGFHNANTS--ALFS---GHSGLLNAG-------------------GSQS MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK GDAGSGGSG-INGGAGGAGG-----------------AGGEGGEGGDGGK MSMEG_0868|M.smegmatis_MC2_155 GDGGVNGTGGASGGDGGNGGNTSVWKSGGQTADGEHNTGGNGGNGGDGSE Rv0355c|M.tuberculosis_H37Rv VGIGGTNSGSFNIGLFNSGTGNVGIGNSGTGNVGIGNTGTGNTGIGNSGN Mb0362c|M.bovis_AF2122/97 VGIGGTNSGSFNIGLFNSGTGNVGIGNSGTGNVGIGNTGTGNTGIGNSGN MMAR_0642|M.marinum_M VGIGGLNSGSFNVGLFNSGTGNVGIGNSGTGNWGIGNSGSHNSGIGNTGS MUL_0965|M.ulcerans_Agy99 VGIN--NTGSFNTVLFNTGFRTAGIANSATNGLLTATSGVANSGNNSSGG MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK GGAG--AEGGAGGGGGAGGSGAGGAG--GAGGSGGSGGSGGSGGSGGAAG MSMEG_0868|M.smegmatis_MC2_155 PGPGGNGAGGAGGNGGTGGTTAGGSGNGGNGGNGGNGGADGTPGTAGTTG Rv0355c|M.tuberculosis_H37Rv YNTGLLNAGLVNTGIANPGNHNTGLFNIGTFNTGIANPGHYNTGSYNTGS Mb0362c|M.bovis_AF2122/97 YNTGLLNAGLVNTGIANPGNHNTGLFNIGTFNTGIANPGHYNTGSYNTGS MMAR_0642|M.marinum_M YNTGLFNSGSFNTGIANPGNFNTGLFNIGVFNTGIANPGDYNTGFYNTGD MUL_0965|M.ulcerans_Agy99 FN-------------ANPD--QSGFFN----------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK DSDD---------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 ANNP---------------------------------------------- Rv0355c|M.tuberculosis_H37Rv YNTGMANAGDYGTGAFITGSMNNGLLWRADRQGLLAANYTITIERPAAFL Mb0362c|M.bovis_AF2122/97 YNTGMANAGDYGTGAFITGSMNNGLLWRADRQGLLAANYTITIERPAAFL MMAR_0642|M.marinum_M YNTGLANIGNFDTGAFITGNMANGVFWRADSMGQLSAHYAITVNRIPAFM MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- Rv0355c|M.tuberculosis_H37Rv NVDIPVNIPITGDITNVSIPAITFPRIDASGSVDIGILSGTVLAPVGPIT Mb0362c|M.bovis_AF2122/97 NVDIPVNIPITGDITNVSIPAITFPRIDASGSVDIGILSGTVLAPVGPIT MMAR_0642|M.marinum_M TIDAPVNIPITGTITDISIPAVTFPKVPATGKVDLAIISGTVIAPIGPIT MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- Rv0355c|M.tuberculosis_H37Rv LHGGDASAPLDTPIEIDFGPSPAINLNIGKPDGSTVINIVGGAGAGPISI Mb0362c|M.bovis_AF2122/97 LHGGDASAPLDTPIEIDFGPSPAINLNIGKPDGSTVINIVGGAGAGPISI MMAR_0642|M.marinum_M IHGGDASAPLNTPIVIDFGTQPALQLNLGNPDGSTVVHVGGYFNFGPGQI MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- Rv0355c|M.tuberculosis_H37Rv PIIDLRPAPGFFNATTGPSSGFLNWGAGSASGLLNFG-NNSGLYNFATSS Mb0362c|M.bovis_AF2122/97 PIIDLRPAPGFFNATTGPSSGFLNWGAGSASGLLNFG-NNSGLYNFATSS MMAR_0642|M.marinum_M PLIDIKPAAGFFNATTGPSSGFFNLGDGSASGFANVGANNSGIWNVATAA MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- Rv0355c|M.tuberculosis_H37Rv MGNSGFQNYGSLQSGWANLGNSISGIYNTGLGAPANVSGLLNIGTNLAGW Mb0362c|M.bovis_AF2122/97 MGNSGFQNYGSLQSGWANLGNSISGIYNTGLGAPANVSGLLNIGTNLAGW MMAR_0642|M.marinum_M LGNSGFQNIGSQQSGLANLGNAISGFLNTGGATPANLSGFQNIGTDLAGW MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- Rv0355c|M.tuberculosis_H37Rv LQNGPTETTFSVGLANLGFWNLGSANIGNYNLGSANIGVYNLGSANIGDF Mb0362c|M.bovis_AF2122/97 LQNGPTETTFSVGLANLGFWNLGSANIGNYNLGSANIGVYNLGSANIGDF MMAR_0642|M.marinum_M YRNGPDATTFSFGIANPGFWNVGSANIGSYNLGNANIGVSNFGFGNLGSA MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- Rv0355c|M.tuberculosis_H37Rv NLGSANIGDFNLGSANIGSSNIGFGNVGPGLTAAIGNIGFGNTGNGNIGI Mb0362c|M.bovis_AF2122/97 NLGSANIGDFNLGSANIGSSNIGFGNVGPGLTAAIGNIGFGNTGNGNIGI MMAR_0642|M.marinum_M NLGSANLGGFNLGSANIGSHNFGFANTGPALSDAIGNIGFGNTGSYNIGF MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- Rv0355c|M.tuberculosis_H37Rv GNTGTGNIGFGNTGNGNIGIGLTGDTMTGFGGWNSGTGNIGLFNSGTGNI Mb0362c|M.bovis_AF2122/97 GNTGTGNIGFGNTGNGNIGIGLTGDTMTGFGGWNSGTGNIGLFNSGTGNI MMAR_0642|M.marinum_M GNTGNGNLGFANTGDGNIGIGLAGDTMTGFGGWNSGSGNIGLFNSGTNNI MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- Rv0355c|M.tuberculosis_H37Rv GFGNSGTGNWGIGNSGDYNTGIGNTGSTNSGFFNTGLVNTGIGNSGDYNT Mb0362c|M.bovis_AF2122/97 GFGNSGTGNWGIGNSGDYNTGIGNTGSTNSGFFNTGLVNTGIGNSGDYNT MMAR_0642|M.marinum_M GFGNSGTGNWGIGNSGSYNTGIGNTGTTNTGFFNSGMVNTGIGNAGNYNT MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- Rv0355c|M.tuberculosis_H37Rv GLFNAGNTNTGSFNPGDYNTGGFNPGNYNTGYFNPGNSNTGIANSGDVNT Mb0362c|M.bovis_AF2122/97 GLFNAGNTNTGSFNPGDYNTGGFNPGNYNTGYFNPGNSNTGFANSGDVNT MMAR_0642|M.marinum_M GCYNTGDFNTGSFNPGDYNTGGFNPGNYNTGYFNEGNSNTGLANSGNVNT MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- Rv0355c|M.tuberculosis_H37Rv GAFNSGNYSNGFFWRGDYQGLGGFAYQSAVSEIPWSYDRFQH-------- Mb0362c|M.bovis_AF2122/97 GAFNSGNYSNGFFWRGDYQGLGGFAYQSAVSEIPWSYDIGSNIEIPIEGD MMAR_0642|M.marinum_M GAFISGNYSNGLLWRGDYQGLLGFTYESTVPAIPWNIGVHSDIDIPITGA MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- Rv0355c|M.tuberculosis_H37Rv -------------------------------------------------- Mb0362c|M.bovis_AF2122/97 INAITQDAFTIDEFEIPIKLRVSVCVIYIPFKGCVKHVSVTIPITTEHLG MMAR_0642|M.marinum_M INTITQDMFTIAEFEIPISLETTICLIYVPFVGCVLHVSVTVPITTEHVG MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- Rv0355c|M.tuberculosis_H37Rv -------------------------------------------------- Mb0362c|M.bovis_AF2122/97 PYEIDASTINPDQPIDTAFTQTLDFAGSGTVGAFPFGFGWQQSPGFFNST MMAR_0642|M.marinum_M PFVIDPSVINPQSPINTAITDTIDFSDAGTVGPATFGFNWQQSPGFFNSS MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- Rv0355c|M.tuberculosis_H37Rv -------------------------------------------------- Mb0362c|M.bovis_AF2122/97 TTPSSGFFNSGAGGASGFLNDAAAAVSGLGNVFTETSGFFNAGGVGNSGF MMAR_0642|M.marinum_M DTPSSGFFNSGAGGASGLLNDAQGAVSGIGNAFLESSGFFNAGGPGLSGL MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- Rv0355c|M.tuberculosis_H37Rv -------------------------------------------------- Mb0362c|M.bovis_AF2122/97 QNFGNLLSGWANLGNTVSGFYNTSMLDLATQALISGFGNHGARLSGILNN MMAR_0642|M.marinum_M QNVGTLESGWANFGNSLSGIYNTSILNLMAQAFVSGLGNTGHELSGFLND MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- Rv0355c|M.tuberculosis_H37Rv ---- Mb0362c|M.bovis_AF2122/97 GSGP MMAR_0642|M.marinum_M AMA- MUL_0965|M.ulcerans_Agy99 ---- MAV_4704|M.avium_104 ---- MLBr_01182|M.leprae_Br4923 ---- MAB_0669|M.abscessus_ATCC_1997 ---- Mvan_0415|M.vanbaalenii_PYR-1 ---- TH_3113|M.thermoresistible__bu ---- Mflv_5091|M.gilvum_PYR-GCK ---- MSMEG_0868|M.smegmatis_MC2_155 ----