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LTRMSLSDTVDLSLSDRRTDIIRDHGIEVTVDKQAQARLRVSRHACELFWEKGVAATTGDDIAAAAGLST RTIWRYFRTKESCVEPVLALSAKRFIALANRWPAELSLADHMAADMAQNPLTETEIADEVAALRIATVSA SEPALRTAYLMVHDEMERGFIPVVARRLRLPEDDLTVRLCAAAVTGAFRVVDEDVGRRTIIEKEKVTQQE ALALIDRAIRDATNGRLGGPVEP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5921 | - | - | 100% (233) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0384 | - | 4e-11 | 34.34% (166) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1157 | - | 2e-09 | 33.75% (160) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3860c | - | 6e-07 | 26.95% (167) | transcriptional regulatory protein TetR-family |
| M. gilvum PYR-GCK | Mflv_4392 | - | 3e-92 | 86.39% (191) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3830c | - | 7e-07 | 26.95% (167) | transcriptional regulatory protein TetR-family |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0248c | - | 2e-08 | 31.85% (157) | TetR family transcriptional regulator |
| M. marinum M | MMAR_4840 | - | 5e-10 | 30.88% (136) | putative regulatory protein |
| M. avium 104 | MAV_4894 | - | 3e-08 | 32.34% (167) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_5522 | - | 8e-81 | 71.50% (200) | TetR family transcriptional regulator protein |
| M. thermoresistible (build 8) | TH_3524 | - | 2e-07 | 30.92% (152) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_3793 | - | 2e-07 | 27.21% (136) | putative regulatory protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_5921|M.vanbaalenii_PYR-1 --------------------------------------------MTRMSL
Mflv_4392|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5522|M.smegmatis_MC2_155 -----------------------------------------------MSI
Mb3860c|M.bovis_AF2122/97 -----------------------------------------------MVR
Rv3830c|M.tuberculosis_H37Rv -----------------------------------------------MVR
MMAR_4840|M.marinum_M MQSASPASVPDIATPAKQPLVLLVSLRYCSYHSAEGSLECRIDEGDVMPS
MUL_3793|M.ulcerans_Agy99 -----------MAS-----------------------------EGDGMSP
MAB_0248c|M.abscessus_ATCC_199 -----------------------------------------------MRP
TH_3524|M.thermoresistible__bu --------------------------------------------------
MAV_4894|M.avium_104 -----------------------------------------------MPA
Mvan_5921|M.vanbaalenii_PYR-1 SDTVDLSLSDRRTDIIRDHGIEVTVDKQAQARLRVSRHACELFWEKG-VA
Mflv_4392|M.gilvum_PYR-GCK ----------------------------------MSRIACDLFWERG-VA
MSMEG_5522|M.smegmatis_MC2_155 SE------------------------KQEQARLDVSRHACKLFWERG-VS
Mb3860c|M.bovis_AF2122/97 PP---------------------QTARSERTREALRQAALVRFLAQG-VE
Rv3830c|M.tuberculosis_H37Rv PP---------------------QTARSERTREALRQAALVRFLAQG-VE
MMAR_4840|M.marinum_M ANTG-----------------SLRDRRRAELLSQIQGTAHQLFAERG-FA
MUL_3793|M.ulcerans_Agy99 ANIG-----------------SLRDRRRAELFSLIQQTAHRLFAERG-FD
MAB_0248c|M.abscessus_ATCC_199 ASG-------------------LREQKKSETKLALSRAALELALDRGDLA
TH_3524|M.thermoresistible__bu -------------------------VRGHRNREALIAAAIDLFTVNG-YE
MAV_4894|M.avium_104 SEAPPG----------------LRERKKIKTRQAIRREAFRLIEQNG-YA
: * .*
Mvan_5921|M.vanbaalenii_PYR-1 ATTGDDIAAAAGLSTRTIWRYFRTKESCVEPVLALSAKRFIALANRWPAE
Mflv_4392|M.gilvum_PYR-GCK ATTGDDIAAEAGLSTRTIWRYFRCKESCVEPVLALSAKRFIGLAERWPAE
MSMEG_5522|M.smegmatis_MC2_155 GTSGDDIAAACGLSTRTIWRYFRSKESCVEPLLARSAERFIEVLRRWPHE
Mb3860c|M.bovis_AF2122/97 ATSAEQIAEDAGVSLRTFYRHFRSKHDLLFADYDAGLHWFRAALDARPAD
Rv3830c|M.tuberculosis_H37Rv ATSAEQIAEDAGVSLRTFYRHFRSKHDLLFADYDAGLHWFRAALDARPAD
MMAR_4840|M.marinum_M AVTTEDIAAASGISISTYFRYAPTKEDLLIAPLRQTVAEIVAAYGTQPSD
MUL_3793|M.ulcerans_Agy99 AVTTEDIAAAAGVSISTYFRHAPTKEGLLVDPVRQAITEIVSSYRSWPAD
MAB_0248c|M.abscessus_ATCC_199 AVTVDDIADAVRVSARTFRNYFTSKEDAVLFSLRGIEDNAVALLRQRPQH
TH_3524|M.thermoresistible__bu QTTVEQIAEAAGVAPRTFFRHFAAKEDILFHGYADRLAEATRRFRAARSG
MAV_4894|M.avium_104 ATTVEQIAEAADVSPSTFFRYFGSKESLLLADDLD--PLILDALKAQPRE
.: ::** :: * .: *.. :
Mvan_5921|M.vanbaalenii_PYR-1 LSLADHMAADMAQNPLTETEIADEVAALRIATVSAS--EPALRTAYLMVH
Mflv_4392|M.gilvum_PYR-GCK LSLAEHMAADMIENPLSEREIADEVAALRIATMSAT--EPALRTSYLMVH
MSMEG_5522|M.smegmatis_MC2_155 LSLSEHLAVNNYSHPFSPQDIEDEISAMRIATMTSS--EPALRTAYLMVH
Mb3860c|M.bovis_AF2122/97 ESIIDSVQAAIFSFPY-DVDAVTKIASLRRGELEPSRIVRHMREVEADFA
Rv3830c|M.tuberculosis_H37Rv ESIIDSVQAAIFSFPY-DVDAVTKIASLRRGELEPSRIVRHMREVEADFA
MMAR_4840|M.marinum_M QSAADALIALFAETAWDKTNP--KPHYWQQAILTAP----HLLSKSALIS
MUL_3793|M.ulcerans_Agy99 ESAVEASIALFVSYARDAGDL--KLDTLRRAIATAP----YLLSKSALVS
MAB_0248c|M.abscessus_ATCC_199 EHVVDSLEAVMLDLATSEAFS-TTVAVTRLSAQNPG-----LAAHDAARS
TH_3524|M.thermoresistible__bu -SLWKALAEASEAVATAIAENPGIFLVRARMYGELP----ALRATMLRIN
MAV_4894|M.avium_104 LSLPQAFRRAYATVLSQLPDDQLEFESTRQRLMFSIP---ELKAAMYDEY
. :
Mvan_5921|M.vanbaalenii_PYR-1 DEMERGFIPVVARRLRLPEDDLTVRLCAAAVTGAFRVVDEDVGRRTIIEK
Mflv_4392|M.gilvum_PYR-GCK DEMERAFVPVIARRLGLPDDDLTARLCAAAVTAAFRVVDEDVGRRAIVDK
MSMEG_5522|M.smegmatis_MC2_155 DQMERGFIPVIADRLGLPETDLTVRLSAAAVTGAFRVVDEDVSRAVIVDG
Mb3860c|M.bovis_AF2122/97 DAIQAQLRRRNCDIAGAPDARLHIAVTARCVAAAVFGAMEAWMLGSDRSL
Rv3830c|M.tuberculosis_H37Rv DAIQAQLRRRNCDIAGAPDARLHIAVTARCVAAAVFGAMEAWMLGSDRSL
MMAR_4840|M.marinum_M DNDGRKFIELVAARMGVDAG---LDIRPSLLVHTALATAQFILRRRLSED
MUL_3793|M.ulcerans_Agy99 EDDQHRFIEHVASRMGVDAR---TDIRPALLVHTSLATVKFVFDRWLSTD
MAB_0248c|M.abscessus_ATCC_199 EDVGTVVLTEVSRRAGLDPD---VDLYPRLVCNAAYAVLATVIQLAVSGS
TH_3524|M.thermoresistible__bu DDWIDQMTTEVARWLGSDAA---VDVRPRLAATVINGANRTAIDLWVSAD
MAV_4894|M.avium_104 YRTVTVAAEAIAHRIGRAADDFEVRVFAGALTGAMMAAFDSAPTTPETIY
. : . . .
Mvan_5921|M.vanbaalenii_PYR-1 EKVTQQEALALIDRAIR---------------------------------
Mflv_4392|M.gilvum_PYR-GCK EKVTQEEALALIDRAIR---------------------------------
MSMEG_5522|M.smegmatis_MC2_155 ENVTEEQTLALIDRAIR---------------------------------
Mb3860c|M.bovis_AF2122/97 GELARVCHVALESLRVG---------------------------------
Rv3830c|M.tuberculosis_H37Rv GELARVCHVALESLRVG---------------------------------
MMAR_4840|M.marinum_M TKTRPPLHVELER-------------------------------------
MUL_3793|M.ulcerans_Agy99 PPSSPIFHVQWTRRCGSRSPDSGNAIRHLPSSRETEPNFVVRHDIWVRPS
MAB_0248c|M.abscessus_ATCC_199 KLSKDPGALVAQG-------------------------------------
TH_3524|M.thermoresistible__bu GKGDLVELMADAVRLVRPTLDR----------------------------
MAV_4894|M.avium_104 RALDFMDAGMPLD-------------------------------------
Mvan_5921|M.vanbaalenii_PYR-1 ---DATNGRLGGPVEP-------------
Mflv_4392|M.gilvum_PYR-GCK ---DATNGRLGGPVTVK------------
MSMEG_5522|M.smegmatis_MC2_155 ---EATNGRLGGPVT--------------
Mb3860c|M.bovis_AF2122/97 ---ISDTWTTLTVSS--------------
Rv3830c|M.tuberculosis_H37Rv ---ISDTWTTLTVSS--------------
MMAR_4840|M.marinum_M ----ALRVTLAGFD---------------
MUL_3793|M.ulcerans_Agy99 GSGSNPRASACSFERMRPCIHHRRHHCTR
MAB_0248c|M.abscessus_ATCC_199 -----FQRLRDGLA---------------
TH_3524|M.thermoresistible__bu --IERESRTVANPVRRRDVV---------
MAV_4894|M.avium_104 -----------------------------