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VSRIACDLFWERGVAATTGDDIAAEAGLSTRTIWRYFRCKESCVEPVLALSAKRFIGLAERWPAELSLAE HMAADMIENPLSEREIADEVAALRIATMSATEPALRTSYLMVHDEMERAFVPVIARRLGLPDDDLTARLC AAAVTAAFRVVDEDVGRRAIVDKEKVTQEEALALIDRAIRDATNGRLGGPVTVK
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4392 | - | - | 100% (194) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0350 | - | 1e-09 | 31.91% (188) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_3024 | - | 5e-06 | 42.22% (45) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3860c | - | 1e-06 | 30.92% (152) | transcriptional regulatory protein TetR-family |
| M. tuberculosis H37Rv | Rv3830c | - | 1e-06 | 30.92% (152) | transcriptional regulatory protein TetR-family |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0248c | - | 7e-08 | 31.37% (153) | TetR family transcriptional regulator |
| M. marinum M | MMAR_3861 | - | 5e-08 | 27.82% (133) | putative regulatory protein |
| M. avium 104 | MAV_2512 | - | 3e-09 | 31.41% (156) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_5522 | - | 9e-77 | 71.88% (192) | TetR family transcriptional regulator protein |
| M. thermoresistible (build 8) | TH_3524 | - | 1e-07 | 30.92% (152) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_3793 | - | 3e-08 | 27.82% (133) | putative regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_5921 | - | 2e-92 | 86.39% (191) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4392|M.gilvum_PYR-GCK ----------------------------------------MSRIACDLFW
Mvan_5921|M.vanbaalenii_PYR-1 MTRMSLSDTVDLSLSDRRTDIIRDHGIEVTVDKQAQARLRVSRHACELFW
MSMEG_5522|M.smegmatis_MC2_155 ---MSISE------------------------KQEQARLDVSRHACKLFW
MMAR_3861|M.marinum_M --MASEGDGMNPANIGSLRD-----------RRRAELFSLIQQTAHRLFA
MUL_3793|M.ulcerans_Agy99 --MASEGDGMSPANIGSLRD-----------RRRAELFSLIQQTAHRLFA
Mb3860c|M.bovis_AF2122/97 --MVRPPQT----------------------ARSERTREALRQAALVRFL
Rv3830c|M.tuberculosis_H37Rv --MVRPPQT----------------------ARSERTREALRQAALVRFL
MAB_0248c|M.abscessus_ATCC_199 ---MRPASGLRE-------------------QKKSETKLALSRAALELAL
MAV_2512|M.avium_104 ---MANPVGLRE-------------------RRRRQTSADIRDAAVRLTL
TH_3524|M.thermoresistible__bu -------------------------------VRGHRNREALIAAAIDLFT
: *
Mflv_4392|M.gilvum_PYR-GCK ERG-VAATTGDDIAAEAGLSTRTIWRYFRCKESCVEPVLALSAKRFIGLA
Mvan_5921|M.vanbaalenii_PYR-1 EKG-VAATTGDDIAAAAGLSTRTIWRYFRTKESCVEPVLALSAKRFIALA
MSMEG_5522|M.smegmatis_MC2_155 ERG-VSGTSGDDIAAACGLSTRTIWRYFRSKESCVEPLLARSAERFIEVL
MMAR_3861|M.marinum_M ERG-FDAVTTEDIAAAAGVSISTYFRHAPTKEGLLVDPVRQAITEIVSSY
MUL_3793|M.ulcerans_Agy99 ERG-FDAVTTEDIAAAAGVSISTYFRHAPTKEGLLVDPVRQAITEIVSSY
Mb3860c|M.bovis_AF2122/97 AQG-VEATSAEQIAEDAGVSLRTFYRHFRSKHDLLFADYDAGLHWFRAAL
Rv3830c|M.tuberculosis_H37Rv AQG-VEATSAEQIAEDAGVSLRTFYRHFRSKHDLLFADYDAGLHWFRAAL
MAB_0248c|M.abscessus_ATCC_199 DRGDLAAVTVDDIADAVRVSARTFRNYFTSKEDAVLFSLRGIEDNAVALL
MAV_2512|M.avium_104 ERG-FDKVTVDEICAEAGISTRTFFNYFPNKESAIAYGPSDIPPELVADF
TH_3524|M.thermoresistible__bu VNG-YEQTTVEQIAEAAGVAPRTFFRHFAAKEDILFHGYADRLAEATRRF
.* .: ::*. :: * .: *.. :
Mflv_4392|M.gilvum_PYR-GCK ERW-PAELSLAEHMAADMIENPLSEREIADEVAALRIATMSATEPALRTS
Mvan_5921|M.vanbaalenii_PYR-1 NRW-PAELSLADHMAADMAQNPLTETEIADEVAALRIATVSASEPALRTA
MSMEG_5522|M.smegmatis_MC2_155 RRW-PHELSLSEHLAVNNYSHPFSPQDIEDEISAMRIATMTSSEPALRTA
MMAR_3861|M.marinum_M RSW-PADESAVEALIALFVSYARDAGDLKLDTWRRAIATA----PYLLSK
MUL_3793|M.ulcerans_Agy99 RSW-PADESAVEASIALFVSYARDAGDLKLDTLRRAIATA----PYLLSK
Mb3860c|M.bovis_AF2122/97 DAR-PADESIIDSVQAAIFSFPYDVDAVTKIASLRRGELE----PSRIVR
Rv3830c|M.tuberculosis_H37Rv DAR-PADESIIDSVQAAIFSFPYDVDAVTKIASLRRGELE----PSRIVR
MAB_0248c|M.abscessus_ATCC_199 RQR-PQHEHVVDSLEAVMLDLATSEAFSTTVAVTRLSAQN----PGLAAH
MAV_2512|M.avium_104 VAAGPAPYSVVLAELIALAAHHLRDVPPRREHAANMLELAKTS-PAVLAA
TH_3524|M.thermoresistible__bu RAARSGSLWKALAEASEAVATAIAENPGIFLVRARMYGEL----PALRAT
. *
Mflv_4392|M.gilvum_PYR-GCK YLMVHDEMERAFVPVIARRLGLPD-DDLTARLCAAAVTAAFRVVDEDVGR
Mvan_5921|M.vanbaalenii_PYR-1 YLMVHDEMERGFIPVVARRLRLPE-DDLTVRLCAAAVTGAFRVVDEDVGR
MSMEG_5522|M.smegmatis_MC2_155 YLMVHDQMERGFIPVIADRLGLPE-TDLTVRLSAAAVTGAFRVVDEDVSR
MMAR_3861|M.marinum_M SALVSEDDQHRFIEHVASRMGVDARTDIRPALLVHTSLATVKFVFDRWLS
MUL_3793|M.ulcerans_Agy99 SALVSEDDQHRFIEHVASRMGVDARTDIRPALLVHTSLATVKFVFDRWLS
Mb3860c|M.bovis_AF2122/97 HMREVEADFADAIQAQLRRRNCDIAGAPDARLHIAVTARCVAAAVFGAME
Rv3830c|M.tuberculosis_H37Rv HMREVEADFADAIQAQLRRRNCDIAGAPDARLHIAVTARCVAAAVFGAME
MAB_0248c|M.abscessus_ATCC_199 DAARSEDVGTVVLTEVSRRAGLDPDVDLYPRLVCNAAYAVLATVIQLAVS
MAV_2512|M.avium_104 FLADLERFQNQLTDIIVRRQGMQPDDEMAP-LISALALTAVRSGIEKWAS
TH_3524|M.thermoresistible__bu MLRINDDWIDQMTTEVARWLGSDAAVDVRPRLAATVINGANRTAIDLWVS
: *
Mflv_4392|M.gilvum_PYR-GCK RAIVDKEKVTQEEALALIDR------------------------------
Mvan_5921|M.vanbaalenii_PYR-1 RTIIEKEKVTQQEALALIDR------------------------------
MSMEG_5522|M.smegmatis_MC2_155 AVIVDGENVTEEQTLALIDR------------------------------
MMAR_3861|M.marinum_M TDPPSSPIFHVQMDQ-----------------------------------
MUL_3793|M.ulcerans_Agy99 TDPPSSPIFHVQWTRRCGSRSPDSGNAIRHLPSSRETEPNFVVRHDIWVR
Mb3860c|M.bovis_AF2122/97 AWMLGSDRSLGELARVCHVA------------------------------
Rv3830c|M.tuberculosis_H37Rv AWMLGSDRSLGELARVCHVA------------------------------
MAB_0248c|M.abscessus_ATCC_199 GSKLSKD--PGALVAQGFQR------------------------------
MAV_2512|M.avium_104 GEASETDDTPMPYVERAAAL------------------------------
TH_3524|M.thermoresistible__bu ADGKGDLVELMADAVRLVRPTLDR--------------------------
Mflv_4392|M.gilvum_PYR-GCK ------AIRDATNGRLGGPVTVK--------
Mvan_5921|M.vanbaalenii_PYR-1 ------AIRDATNGRLGGPVEP---------
MSMEG_5522|M.smegmatis_MC2_155 ------AIREATNGRLGGPVT----------
MMAR_3861|M.marinum_M ------ALRIALAGFR---------------
MUL_3793|M.ulcerans_Agy99 PSGSGSNPRASACSFERMRPCIHHRRHHCTR
Mb3860c|M.bovis_AF2122/97 ----LESLRVGISDTWTTLTVSS--------
Rv3830c|M.tuberculosis_H37Rv ----LESLRVGISDTWTTLTVSS--------
MAB_0248c|M.abscessus_ATCC_199 -------LRDGLA------------------
MAV_2512|M.avium_104 -------VNSIFTK-----------------
TH_3524|M.thermoresistible__bu ---IERESRTVANPVRRRDVV----------
.