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VSISEKQEQARLDVSRHACKLFWERGVSGTSGDDIAAACGLSTRTIWRYFRSKESCVEPLLARSAERFIE VLRRWPHELSLSEHLAVNNYSHPFSPQDIEDEISAMRIATMTSSEPALRTAYLMVHDQMERGFIPVIADR LGLPETDLTVRLSAAAVTGAFRVVDEDVSRAVIVDGENVTEEQTLALIDRAIREATNGRLGGPVT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5522 | - | - | 100% (205) | TetR family transcriptional regulator protein |
| M. smegmatis MC2 155 | MSMEG_1420 | - | 1e-07 | 27.78% (144) | transcriptional regulatory protein |
| M. smegmatis MC2 155 | MSMEG_2071 | - | 4e-06 | 38.78% (98) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0310 | - | 3e-07 | 27.08% (144) | TetR/ACRR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4392 | - | 8e-77 | 71.88% (192) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0302 | - | 9e-07 | 26.39% (144) | TetR/ACRR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3586c | - | 8e-07 | 40.91% (66) | TetR family transcriptional regulator |
| M. marinum M | MMAR_3861 | - | 3e-08 | 28.76% (153) | putative regulatory protein |
| M. avium 104 | MAV_4894 | - | 1e-08 | 31.01% (158) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_0641 | - | 3e-07 | 45.83% (72) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_3793 | - | 8e-08 | 28.10% (153) | putative regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_5921 | - | 6e-81 | 71.50% (200) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0310|M.bovis_AF2122/97 ---MGVPAKKKQ-------------------QQGERSRESILDATERLMA
Rv0302|M.tuberculosis_H37Rv ---MGVPAKKKQ-------------------QQGERSRESILDATERLMA
Mflv_4392|M.gilvum_PYR-GCK ----------------------------------------MSRIACDLFW
Mvan_5921|M.vanbaalenii_PYR-1 MTRMSLSDTVDLSLSDRRTDIIRDHGIEVTVDKQAQARLRVSRHACELFW
MSMEG_5522|M.smegmatis_MC2_155 ---MSISE------------------------KQEQARLDVSRHACKLFW
MMAR_3861|M.marinum_M --MASEGDGMNPANIGSLRD-----------RRRAELFSLIQQTAHRLFA
MUL_3793|M.ulcerans_Agy99 --MASEGDGMSPANIGSLRD-----------RRRAELFSLIQQTAHRLFA
MAV_4894|M.avium_104 MPASEAPPGLRE-------------------RKKIKTRQAIRREAFRLIE
MAB_3586c|M.abscessus_ATCC_199 -----MPRVVKH---------------------PELRRTELLDLAMTLFL
TH_0641|M.thermoresistible__bu ----MAAETLSS--------------------KGRQTRLALEQAARKLFA
: : *:
Mb0310|M.bovis_AF2122/97 TKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAMMERGAQRFFAAIP
Rv0302|M.tuberculosis_H37Rv TKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAMMERGAQRFFAAIP
Mflv_4392|M.gilvum_PYR-GCK ERGVAATTGDDIAAEAGLSTRTIWRYFRCKESCVEPVLALSAKRFIGLAE
Mvan_5921|M.vanbaalenii_PYR-1 EKGVAATTGDDIAAAAGLSTRTIWRYFRTKESCVEPVLALSAKRFIALAN
MSMEG_5522|M.smegmatis_MC2_155 ERGVSGTSGDDIAAACGLSTRTIWRYFRSKESCVEPLLARSAERFIEVLR
MMAR_3861|M.marinum_M ERGFDAVTTEDIAAAAGVSISTYFRHAPTKEGLLVDPVRQAITEIVSSYR
MUL_3793|M.ulcerans_Agy99 ERGFDAVTTEDIAAAAGVSISTYFRHAPTKEGLLVDPVRQAITEIVSSYR
MAV_4894|M.avium_104 QNGYAATTVEQIAEAADVSPSTFFRYFGSKESLLLADDLD--PLILDALK
MAB_3586c|M.abscessus_ATCC_199 ERGYERVSLNDLIATSGMSKGAFYHYFSSKEALVSALAARSADQAFEALR
TH_0641|M.thermoresistible__bu ERGFHGTTLADITSAAGKSPAVFYRYFVDKEDLLAALAESFLREVLAPGW
.* .: :: .. : : : ** : .
Mb0310|M.bovis_AF2122/97 TWDEAHGPVEQRSERQLTELVSLQSQHPDFLRLFYLLSMERSQDPVVAAV
Rv0302|M.tuberculosis_H37Rv TWDEAHGPVEQRSERQLTELVSLQSQHPDFLRLFYLLSMERSQDPAVAAV
Mflv_4392|M.gilvum_PYR-GCK RWPAELSLAEHMAADMIENPLSEREIADEVAALR--IATMSATEPALRTS
Mvan_5921|M.vanbaalenii_PYR-1 RWPAELSLADHMAADMAQNPLTETEIADEVAALR--IATVSASEPALRTA
MSMEG_5522|M.smegmatis_MC2_155 RWPHELSLSEHLAVNNYSHPFSPQDIEDEISAMR--IATMTSSEPALRTA
MMAR_3861|M.marinum_M SWPADESAVEALIALFVSYARDAGDLKLDTWRRA--IATA----PYLLSK
MUL_3793|M.ulcerans_Agy99 SWPADESAVEASIALFVSYARDAGDLKLDTLRRA--IATA----PYLLSK
MAV_4894|M.avium_104 AQPRELSLPQAFRRAYATVLSQLPDDQLEFESTR---QRLMFSIPELKAA
MAB_3586c|M.abscessus_ATCC_199 --PVFEAQGRGALERLNSGLRAGYEVKMALGAPESIGAMASMMRPENQSL
TH_0641|M.thermoresistible__bu LSVRLPDSPDD-DEFFTTVVGGYWNMFKQNIGIMIAVDQLAATQQRFADV
.
Mb0310|M.bovis_AF2122/97 VRRVRNTAIARFRDSIT-HLLPSDIPPGKADLVVAELTAFAVALSDGVYF
Rv0302|M.tuberculosis_H37Rv VRRVRNTAIARFRDSIT-HLLPSDIPPGKADLVVAELTAFAVALSDGVYF
Mflv_4392|M.gilvum_PYR-GCK YLMVHDEMERAFVPVIARRLGLPD-DDLTARLCAAAVTAAFRVVDEDVGR
Mvan_5921|M.vanbaalenii_PYR-1 YLMVHDEMERGFIPVVARRLRLPE-DDLTVRLCAAAVTGAFRVVDEDVGR
MSMEG_5522|M.smegmatis_MC2_155 YLMVHDQMERGFIPVIADRLGLPE-TDLTVRLSAAAVTGAFRVVDEDVSR
MMAR_3861|M.marinum_M SALVSEDDQHRFIEHVASRMGVDARTDIRPALLVHTSLATVKFVFDRWLS
MUL_3793|M.ulcerans_Agy99 SALVSEDDQHRFIEHVASRMGVDARTDIRPALLVHTSLATVKFVFDRWLS
MAV_4894|M.avium_104 MYDEYYRTVTVAAEAIAHRIGRAA-DDFEVRVFAGALTGAMMAAFDSAPT
MAB_3586c|M.abscessus_ATCC_199 LRRISAIWEDRFRPVLTEVIAQGVAEGVFDTFDPEGVGDMIQGLAATMGT
TH_0641|M.thermoresistible__bu QNEFRRFGMDIVAASVRHAQQQGYGTDLDPQHIAAAIALMFENFTAVFVG
:
Mb0310|M.bovis_AF2122/97 AGHLEPDTTDVERMYR----------------------------------
Rv0302|M.tuberculosis_H37Rv AGHLEPDTTDVERMYR----------------------------------
Mflv_4392|M.gilvum_PYR-GCK RAIVDKEKVTQEEALALIDR------------------------------
Mvan_5921|M.vanbaalenii_PYR-1 RTIIEKEKVTQQEALALIDR------------------------------
MSMEG_5522|M.smegmatis_MC2_155 AVIVDGENVTEEQTLALIDR------------------------------
MMAR_3861|M.marinum_M TDPPSSPIFHVQMDQ-----------------------------------
MUL_3793|M.ulcerans_Agy99 TDPPSSPIFHVQWTRRCGSRSPDSGNAIRHLPSSRETEPNFVVRHDIWVR
MAV_4894|M.avium_104 TPETIYRALDFMDAGMPLD-------------------------------
MAB_3586c|M.abscessus_ATCC_199 AVQRIIAAPDAPARAQAIDAAVLRQRLYG---------------------
TH_0641|M.thermoresistible__bu RGGPGLQISDADAVRTLAT-------------------------------
Mb0310|M.bovis_AF2122/97 ------RLRQALEALIPVLLEET------------
Rv0302|M.tuberculosis_H37Rv ------RLRQALEALIPVLLEET------------
Mflv_4392|M.gilvum_PYR-GCK ------AIRDATNGRLGGPVTVK------------
Mvan_5921|M.vanbaalenii_PYR-1 ------AIRDATNGRLGGPVEP-------------
MSMEG_5522|M.smegmatis_MC2_155 ------AIREATNGRLGGPVT--------------
MMAR_3861|M.marinum_M ------ALRIALAGFR-------------------
MUL_3793|M.ulcerans_Agy99 PSGSGSNPRASACSFERMRPCIHHRRHHCTR----
MAV_4894|M.avium_104 -----------------------------------
MAB_3586c|M.abscessus_ATCC_199 ------IATDRILGLPDGTVEVLDRDQIEALVAML
TH_0641|M.thermoresistible__bu ------IWKKTLYGC--------------------