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VQSASPASVPDIATPAKQPLVLLVSLRYCSYHSAEGSLECRIDEGDVMPSANTGSLRDRRRAELLSQIQG TAHQLFAERGFAAVTTEDIAAASGISISTYFRYAPTKEDLLIAPLRQTVAEIVAAYGTQPSDQSAADALI ALFAETAWDKTNPKPHYWQQAILTAPHLLSKSALISDNDGRKFIELVAARMGVDAGLDIRPSLLVHTALA TAQFILRRRLSEDTKTRPPLHVELERALRVTLAGFD
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4840 | - | - | 100% (246) | putative regulatory protein |
| M. marinum M | MMAR_3861 | - | 1e-66 | 63.37% (202) | putative regulatory protein |
| M. marinum M | MMAR_3853 | - | 3e-09 | 27.27% (176) | putative regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2534 | - | 2e-08 | 44.93% (69) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_3877 | - | 2e-09 | 38.38% (99) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv2506 | - | 2e-08 | 44.93% (69) | TetR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0248c | - | 1e-11 | 26.29% (175) | TetR family transcriptional regulator |
| M. avium 104 | MAV_2391 | - | 2e-63 | 64.00% (200) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_1420 | - | 6e-10 | 28.72% (195) | transcriptional regulatory protein |
| M. thermoresistible (build 8) | TH_0641 | - | 4e-07 | 40.00% (75) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_3793 | - | 3e-60 | 62.18% (193) | putative regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_0989 | - | 8e-12 | 37.11% (97) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2534|M.bovis_AF2122/97 ---------------------------------------MTASAPDGRPG
Rv2506|M.tuberculosis_H37Rv ---------------------------------------MTASAPDGRPG
MMAR_4840|M.marinum_M MQSASPASVPDIATPAKQPLVLLVSLRYCSYHSAEGSLECRIDEGDVMP-
MAV_2391|M.avium_104 -----------------------------------------------MP-
MUL_3793|M.ulcerans_Agy99 ----------------------------------------MASEGDGMS-
MSMEG_1420|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0248c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_3877|M.gilvum_PYR-GCK ----------------MPSLHSSADRPHSGQIRMPRPVQGVGCHTVPVTQ
Mvan_0989|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0641|M.thermoresistible__bu --------------------------------------------------
Mb2534|M.bovis_AF2122/97 QPEATNRRSQLKSDRRFQLLAAAERLFAERG-FLAVRLEDIGAAAGVSGP
Rv2506|M.tuberculosis_H37Rv QPEATNRRSQLKSDRRFQLLAAAERLFAERG-FLAVRLEDIGAAAGVSGP
MMAR_4840|M.marinum_M SANTGSLRDRRRAELLSQIQGTAHQLFAERG-FAAVTTEDIAAASGISIS
MAV_2391|M.avium_104 SANSSSLRDRRRAELLSQIQQTAHQLFAERG-FEAVTTEDIAAAAGISIS
MUL_3793|M.ulcerans_Agy99 PANIGSLRDRRRAELFSLIQQTAHRLFAERG-FDAVTTEDIAAAAGVSIS
MSMEG_1420|M.smegmatis_MC2_155 -MSEGSRAGRRRSTTQDHIAGVAIDLFAARG-FDAVSVDDVAAAAGISRR
MAB_0248c|M.abscessus_ATCC_199 MRPASGLREQKKSETKLALSRAALELALDRGDLAAVTVDDIADAVRVSAR
Mflv_3877|M.gilvum_PYR-GCK SGETRGLRERKKAATRLAIRREAFRLFEDQG-YANTTVEQIADAAEISPS
Mvan_0989|M.vanbaalenii_PYR-1 MTATPSLHEQRRRSTREALRRAALASFAARG-FANVTVTELARAAGVTER
TH_0641|M.thermoresistible__bu -MAAETLSSKGR-QTRLALEQAARKLFAERG-FHGTTLADITSAAGKSPA
: : : * :* . :: * :
Mb2534|M.bovis_AF2122/97 AIYRHFPNKESLLVELLVGVSARLLAG--ARDVTTRSANLAAALDGLIEF
Rv2506|M.tuberculosis_H37Rv AIYRHFPNKESLLVELLVGVSARLLAG--ARDVTTRSANLAAALDGLIEF
MMAR_4840|M.marinum_M TYFRYAPTKEDLLIAPLRQTVAEIVAA--YGTQPSDQSAADALIALFAET
MAV_2391|M.avium_104 TYFRYAPTKEGLLVDPAREVAATIVGA--YRTRPAHESAVEALIQLFVTH
MUL_3793|M.ulcerans_Agy99 TYFRHAPTKEGLLVDPVRQAITEIVSS--YRSWPADESAVEASIALFVSY
MSMEG_1420|M.smegmatis_MC2_155 TLFRYYASKSAIPWGDFDSHLQHLQNL--LRTLSSEVSLGDALREALLTF
MAB_0248c|M.abscessus_ATCC_199 TFRNYFTSKEDAVLFSLRGIEDNAVAL--LRQRPQHEHVVDSLEAVMLDL
Mflv_3877|M.gilvum_PYR-GCK TFYRYFAVKEAVLLS--DDHTTPIVDA--FVAAPSDMSPIAAYRHAVAEV
Mvan_0989|M.vanbaalenii_PYR-1 TFFRHFPTKEAVLFQDYETQVEWLAAA--LARRPGSESVFDAVRAAIAEF
TH_0641|M.thermoresistible__bu VFYRYFVDKEDLLAALAESFLREVLAPGWLSVRLPDSPDDDEFFTTVVGG
. .: *. .
Mb2534|M.bovis_AF2122/97 HLDFALG--EADLIRIQDRDLAHLPAVAERQVRKAQRQYVEVWVGVLREL
Rv2506|M.tuberculosis_H37Rv HLDFALG--EADLIRIQDRDLAHLPAVAERQVRKAQRQYVEVWVGVLREL
MMAR_4840|M.marinum_M AWDKTNP--KPHYWQQAILTAPHLLSKSALISDNDGRKFIELVAARMGVD
MAV_2391|M.avium_104 AKEVGAAG-DFDTWRHAVATAPHLLRKSVLMSETDHSNLIQQVAARMNVT
MUL_3793|M.ulcerans_Agy99 ARDAGDL--KLDTLRRAIATAPYLLSKSALVSEDDQHRFIEHVASRMGVD
MSMEG_1420|M.smegmatis_MC2_155 NTYADHEMAEHRQRMRVILETEELQAYSMTMYAGWRTVIAEYVADRLGMS
MAB_0248c|M.abscessus_ATCC_199 ATSEAFS--TTVAVTRLSAQNPGLAAHDAARSEDVGTVVLTEVSRRAGLD
Mflv_3877|M.gilvum_PYR-GCK FAGLSPE----------ERDNAILGQRLLYTVPDARGLVYNEYVRLLGLI
Mvan_0989|M.vanbaalenii_PYR-1 PYDLEVVR-QAATARSELISAERIAGHLRVVQSSFADVLTGHIRTRYAGT
TH_0641|M.thermoresistible__bu YWNMFKQNIGIMIAVDQLAATQQRFADVQNEFRRFGMDIVAASVRHAQQQ
Mb2534|M.bovis_AF2122/97 NPGLAEADARLMAHAVFGLLNSTPHSMKAADSKPARTVRARAVLR-----
Rv2506|M.tuberculosis_H37Rv NPGLAEADARLMAHAVFGLLNSTPHSMKAADSKPARTVRARAVLR-----
MMAR_4840|M.marinum_M AG--LDIRPSLLVHTALATAQFILRRRLSEDTKTRPPLHVELER------
MAV_2391|M.avium_104 AA--LDIRPALLVHTSLATVQFVLDGWLSSDSDESRPFHEQLEE------
MUL_3793|M.ulcerans_Agy99 AR--TDIRPALLVHTSLATVKFVFDRWLSTDPPSSPIFHVQWTRRCGSRS
MSMEG_1420|M.smegmatis_MC2_155 TT---DLMPQTVAWLMLGVALSAYENWLADESVSLRGAIAAAFE------
MAB_0248c|M.abscessus_ATCC_199 PD--VDLYPRLVCNAAYAVLATVIQLAVSGSKLSKDPG------------
Mflv_3877|M.gilvum_PYR-GCK ADGLAHRLPEPTDAMERRVIAGAVVGVLIAASHNNPLPG-----------
Mvan_0989|M.vanbaalenii_PYR-1 AD--IDLVADVAGAALAAALVVAVEHWGRNGCVDDLGEITSAS-------
TH_0641|M.thermoresistible__bu GYG-TDLDPQHIAAAIALMFENFTAVFVGRGGPGLQISDADAVR------
. .
Mb2534|M.bovis_AF2122/97 -------------------------------------AMTVAALSAADRC
Rv2506|M.tuberculosis_H37Rv -------------------------------------AMTVAALSAADRC
MMAR_4840|M.marinum_M -----------------------------------ALRVTLAGFD-----
MAV_2391|M.avium_104 -----------------------------------ALRITLAGFDRPSDA
MUL_3793|M.ulcerans_Agy99 PDSGNAIRHLPSSRETEPNFVVRHDIWVRPSGSGSNPRASACSFERMRPC
MSMEG_1420|M.smegmatis_MC2_155 --------------------------------------VARPGLDALQPA
MAB_0248c|M.abscessus_ATCC_199 -------------------------------------ALVAQGFQRLRDG
Mflv_3877|M.gilvum_PYR-GCK -------------------------------------DVVDRALTFLDSR
Mvan_0989|M.vanbaalenii_PYR-1 ------------------------------------MAVLRSGFARLT--
TH_0641|M.thermoresistible__bu -------------------------------------TLATIWKKTLYGC
Mb2534|M.bovis_AF2122/97 L---------
Rv2506|M.tuberculosis_H37Rv L---------
MMAR_4840|M.marinum_M ----------
MAV_2391|M.avium_104 TPGRR-----
MUL_3793|M.ulcerans_Agy99 IHHRRHHCTR
MSMEG_1420|M.smegmatis_MC2_155 H---------
MAB_0248c|M.abscessus_ATCC_199 LA--------
Mflv_3877|M.gilvum_PYR-GCK LL--------
Mvan_0989|M.vanbaalenii_PYR-1 ----------
TH_0641|M.thermoresistible__bu ----------