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MNSAIVAPEVPTAPIHDLTGKNAVITGGSKGIGAATVARFVAGGARVVTSGRSQPDSLPTGVEYVVADVA TLDGVDLLARRAREILGDIDIIVNNAGATVPHLGGVLDIEDAEWVNDLNINFLAAVRLNAALLPALYARG KGSIINVSSAVTLSPPSPMLHYATAKAALATYTTGLAAEAGPRGVRVNTLTPGTVGSPGADAIRRAIIDG VGADRPEAGGIPIPLGRKGEASDIAEAIAFLASDRAAWITGSNLIVDGGQIQTR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5918 | - | - | 100% (264) | short chain dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_5573 | - | 6e-31 | 35.16% (256) | short chain dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_0614 | - | 6e-31 | 37.25% (247) | short-chain dehydrogenase/reductase SDR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2788c | fabG | 7e-32 | 35.57% (253) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. gilvum PYR-GCK | Mflv_0943 | - | 1e-116 | 80.15% (262) | short chain dehydrogenase |
| M. tuberculosis H37Rv | Rv2766c | fabG | 7e-32 | 35.57% (253) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 1e-22 | 29.29% (239) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_4632 | - | 5e-28 | 32.43% (259) | short chain dehydrogenase |
| M. marinum M | MMAR_1952 | fabG | 3e-32 | 35.97% (253) | short-chain type dehydrogenase/reductase |
| M. avium 104 | MAV_3655 | fabG | 2e-32 | 36.72% (256) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. smegmatis MC2 155 | MSMEG_0283 | - | 9e-41 | 37.94% (253) | short chain dehydrogenase |
| M. thermoresistible (build 8) | TH_3708 | - | 1e-30 | 34.50% (258) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_2173 | fabG | 7e-32 | 35.57% (253) | 3-ketoacyl-(acyl-carrier-protein) reductase |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_5918|M.vanbaalenii_PYR-1 -MNSAIVAPEVPTAPIHDLTGKNAVITGGSKGIGAATVARFVAGGARVVT
Mflv_0943|M.gilvum_PYR-GCK -MSSTIVAPSVDATPIQDLAGKTAIITGGSKGIGAATVARFVRGGARVVT
MSMEG_0283|M.smegmatis_MC2_155 ------------MSNQRPLEGRRALVTGGTKGAGAAVVRTLRASGAHVTA
MAB_4632|M.abscessus_ATCC_1997 --------MILD---RFKLDGNVAVVTGAGRGLGAAIAEAFAQAGADVLI
TH_3708|M.thermoresistible__bu --------MTPDPLAAFRLDGKVALVTGGSRGLGFEMARAFAGAGADVII
Mb2788c|M.bovis_AF2122/97 -------------MTSLDLTGRTAIITGASRGIGLAIAQQLAAAGAHVVL
Rv2766c|M.tuberculosis_H37Rv -------------MTSLDLTGRTAIITGASRGIGLAIAQQLAAAGAHVVL
MAV_3655|M.avium_104 -------------MTSQDLTGRTAIITGASRGIGLAIAQQLAAAGANVVL
MMAR_1952|M.marinum_M -------------MTSLDLTGRTAIITGASRGIGLAIAQRLAGAGANVVL
MUL_2173|M.ulcerans_Agy99 -------------MTSLDLTGRTAIITGASRGIGLAIAQRLAGAGANVVL
MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
: .. ::**. :* * . : * *
Mvan_5918|M.vanbaalenii_PYR-1 SGRSQPDSLPTGVEY----------VVADVATLDGVDLLARRAREILGDI
Mflv_0943|M.gilvum_PYR-GCK SGRSTPGPLPDGVEY----------VVADVATVDGVEHLARRAQQILGDI
MSMEG_0283|M.smegmatis_MC2_155 VARRPGG---DADEF----------VAADVMSEAGIAEIATHVRATGG-V
MAB_4632|M.abscessus_ATCC_1997 ASRTESQLREVAAKV-QAAGRQAEVVVADLSDTEASAALAQKAVDRFGRL
TH_3708|M.thermoresistible__bu SSRDEESCRRAAEEIGRTFAVRAVPMPCHVGRWAELDALADRALATFGHV
Mb2788c|M.bovis_AF2122/97 TARRQEAADEAAAQV----GDRALGVGAHAVDEDAARRCVDLTLERFGSV
Rv2766c|M.tuberculosis_H37Rv TARRQEAADEAAAQV----GDRALGVGAHAVDEDAARRCVDLTLERFGSV
MAV_3655|M.avium_104 TARKQEAADEAAAQV----GPQALGVGAHAVDEDAARQCVQLTLERFGSV
MMAR_1952|M.marinum_M TARKQESADAAAAEV----GERAVGVGAHAVDEEAARGCVDLALERFGSV
MUL_2173|M.ulcerans_Agy99 TARKQESADAAAAEV----GERAVGVGAHAVDEEAARGCVDLALERFGSV
MLBr_01807|M.leprae_Br4923 THRASVVPDWFFG------------VECDVTDNDAIGAAFKAVEEHQGPV
* : .. . * :
Mvan_5918|M.vanbaalenii_PYR-1 DIIVNNAGATVPHLGGVLDIEDAEWVNDLNINFLAAVRLNAALLPALYAR
Mflv_0943|M.gilvum_PYR-GCK DIVVNNAGATTLSLGGVLGITDADWRKDLDINFLAAVRLNAALLPAMYTR
MSMEG_0283|M.smegmatis_MC2_155 HILVHVAGGSSSPAGGFAALSEQDWIDELNLNLLSAVRLDRAVAPMMIEA
MAB_4632|M.abscessus_ATCC_1997 DVVVNNVGGT--MPKPFLDTTNDDLAEAFSFNVLSGHALLRAAVPHLLKS
TH_3708|M.thermoresistible__bu DVLVNNAGMSP-LYDKVADITETMWEKTLAVNLRAPFRLTALLAPAMVDN
Mb2788c|M.bovis_AF2122/97 DILINNAGTNP-AYGPLLEQDHARFAKIFDVNLWAPLMWTSLVVTAWMGE
Rv2766c|M.tuberculosis_H37Rv DILINNAGTNP-AYGPLLEQDHARFAKIFDVNLWAPLMWTSLVVTAWMGE
MAV_3655|M.avium_104 DILVNNAGTNP-AYGPLIEQDHARFAKIFDVNLWAPLLWTSLAVKSWMGE
MMAR_1952|M.marinum_M DILINNAGTNP-AYGPLIEQDHARFTKIFDVNLWAPLMWTSLVVKAWMGE
MUL_2173|M.ulcerans_Agy99 DILINNAGTNP-AYGPLIEQDHARFTKIFDVNLWAPLMWTSLVVKAWMGE
MLBr_01807|M.leprae_Br4923 EVLVANAGITS--DMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQ
.::: .* . . . . : .*. .
Mvan_5918|M.vanbaalenii_PYR-1 GKGSIINVSSAVTLSPPSP-MLHYATAKAALATYTTGLAAEAGPRGVRVN
Mflv_0943|M.gilvum_PYR-GCK GAGSIVNVSSTVILSPPAP-MLHYATAKAALATYTTGLAAEAGPRGVRVN
MSMEG_0283|M.smegmatis_MC2_155 GGGVIVHISSIQSRMPLYDGTLGYAAAKAALRTYSKGLANELAPKGIRVN
MAB_4632|M.abscessus_ATCC_1997 DNASVINITSTMGRLPGRA-FLGYCTAKGALAHYTRTAAMDLSPR-IRVN
TH_3708|M.thermoresistible__bu GGGSVINLSSIGAVRPTAD-IVPYAAAKAGLNAMTAALAKEYGPH-VRVN
Mb2788c|M.bovis_AF2122/97 HGGAVVNTASIGGMHQSPA-MGMYNATKAALIHVTKQLALELSPR-IRVN
Rv2766c|M.tuberculosis_H37Rv HGGAVVNTASIGGMHQSPA-MGMYNATKAALIHVTKQLALELSPR-IRVN
MAV_3655|M.avium_104 HGGSIVNTASIGGLHQSPA-MGMYNATKAALIHVTKQLALELSPR-VRVN
MMAR_1952|M.marinum_M HGGVVINTASIGGMHQSPA-MGMYNATKAALIHVTKQLALELSPR-VRVN
MUL_2173|M.ulcerans_Agy99 HGGVVINTASIGGMHQSPA-MGMYNATNAALIHVTKQLALELSPR-VRVN
MLBr_01807|M.leprae_Br4923 RFGRYIFMGSVVGLSGVPG-QANYAASKSGLIGMARSLARELGSRSITAN
. : * * :::..* : * : ..: : .*
Mvan_5918|M.vanbaalenii_PYR-1 TLTPGTVGSPGADAIRRAIIDGV------GADRPEAGGIPIPLGRKGEAS
Mflv_0943|M.gilvum_PYR-GCK TVTPGNVTSPGADAIRQAIVDSG------GADAPAAGGTPIPLGRKGEAS
MSMEG_0283|M.smegmatis_MC2_155 TVSPGFIRTTAAEALIERIAEAGNGTREQALDSLMASLGGIPLGRPAEPD
MAB_4632|M.abscessus_ATCC_1997 GIAPGSILTSALEVVAGNDEMRN------------TLEQNTPLHRLGDPA
TH_3708|M.thermoresistible__bu AIMPGAFATDVSEYWSAEAVAR--------------VVDQTALGRIGDPR
Mb2788c|M.bovis_AF2122/97 AICPGVVRTRLAEALWKDHEDP--------------LAATIALGRIGEPA
Rv2766c|M.tuberculosis_H37Rv AICPGVVRTRLAEALWKDHEDP--------------LAATIALGRIGEPA
MAV_3655|M.avium_104 AIAPGVVRTRLAEALWKDHEDP--------------LSSSIALGRIGEPI
MMAR_1952|M.marinum_M AICPGVVRTKLAEALWKDHEDP--------------LAANIALGRIGEPV
MUL_2173|M.ulcerans_Agy99 AICPGVVRTKLAEALWKDHEDP--------------LAANIALGRIGEPV
MLBr_01807|M.leprae_Br4923 VVAPGFIDTEMTRAMDSKYQEA--------------ALQAIPLGRIGAVE
: ** . : .* * .
Mvan_5918|M.vanbaalenii_PYR-1 DIAEAIAFLASDRAAWITGSNLIVDGGQIQTR------------
Mflv_0943|M.gilvum_PYR-GCK DIAEAIAFLVSDRAAWITATNLVIDGGQIQAG------------
MSMEG_0283|M.smegmatis_MC2_155 EVAGVVGFLVSDAAASVVGADIVVDGGTVPAI------------
MAB_4632|M.abscessus_ATCC_1997 DIAAAAVYLASPAGSFLTGKVLEVDGGLIAPNLDIPLPDLA---
TH_3708|M.thermoresistible__bu EIVGTALYLASDAASFTSGAVITVDGGRD---------------
Mb2788c|M.bovis_AF2122/97 DIASAVAFLVSDAASWITGETMIIDGGLLLGNALGFRAAPSTEH
Rv2766c|M.tuberculosis_H37Rv DIASAVAFLVSDAASWITGETMIIDGGLLLGNALGFRAAPSTEH
MAV_3655|M.avium_104 DVAAAVAFLVSDAASWITGETLVIDGGTVLGAAQGFRSAPTPS-
MMAR_1952|M.marinum_M DVAEAVGFLVSDAASWITGETMVIDGGLLLGSAAGFQSRPGSAS
MUL_2173|M.ulcerans_Agy99 DVAEAVGFLVSDAASWITGETMVIDGGLLLGSAAGFQSRPGSAS
MLBr_01807|M.leprae_Br4923 EIAGAVSFLASEDAGYISGAVIPVDGGLGMGH------------
::. . :*.* .. . : :***