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MGSDRSDGMARRRRALHFALKGRRDPASGAGQRRRTSGRLSERHTRKVLDLTIRLAEVMLSSGSGTADVV ATAQDVAQAYQLTDCVVDVFVTTIFVSALPTADSPPVTIVRAVQARSTDYTRLADLDRLVRRITSGGVSV DEAHEAMDELSEQPHPYPRWIATAGWAGFALGIAMLLGGTWLTCILAAGTSVLIDRSGRLLNRVGTPMFF QQAAGASIATLVAVAAFLFAGQGPTTLVATGIVMLLAGMTLVGSVQDALTGYMLTAVARLGDVLFLTLGI VVGILAGLQIAALAGIQIQLRVDATEYFVVPTTPRQIVVAVSGAALAGACLVIASYAKWRSVLTAGVAAG LAEAVLIGLGRAGVGQVVATGTAAVGVGLLATLISIRRQAPALVTATAGITPMLPGMAVFRAVFYFAVER DFAAGMAQALAAAATALAIGAGVVMGELAGSPLRYRAGRISDFLRVEGPPGLRRAVGNVVALRPAADQQS SRSPHQRSWSVALEPELSEVATEANGEDPAPERDATGER
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5838 | - | - | 100% (529) | hypothetical protein Mvan_5838 |
| M. vanbaalenii PYR-1 | Mvan_5693 | - | 2e-05 | 25.41% (244) | sulphate transporter |
| M. vanbaalenii PYR-1 | Mvan_2837 | - | 2e-05 | 28.43% (299) | hypothetical protein Mvan_2837 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3764 | - | 0.0 | 71.51% (530) | transmembrane protein |
| M. gilvum PYR-GCK | Mflv_0954 | - | 0.0 | 75.82% (521) | hypothetical protein Mflv_0954 |
| M. tuberculosis H37Rv | Rv3737 | - | 0.0 | 71.51% (530) | transmembrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1627 | - | 2e-05 | 25.15% (338) | hypothetical protein MAB_1627 |
| M. marinum M | MMAR_3034 | - | 0.0 | 68.51% (524) | transmembrane protein |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_3459 | - | 0.0 | 71.65% (508) | hypothetical protein MSMEG_3459 |
| M. thermoresistible (build 8) | TH_0424 | - | 0.0 | 69.83% (527) | PROBABLE CONSERVED TRANSMEMBRANE PROTEIN |
| M. ulcerans Agy99 | MUL_2274 | - | 0.0 | 68.51% (524) | transmembrane protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_5838|M.vanbaalenii_PYR-1 --------MGSDR-------------------SDGMARRRRALHFALKGR
Mflv_0954|M.gilvum_PYR-GCK ---MLPSPMVPSRQPRTPVPFRRASVSWPPMEPDSTPRFRRGLRIAMRGR
Mb3764|M.bovis_AF2122/97 ---------------------------MDQDRSDNTA-LRRGLRIALRGR
Rv3737|M.tuberculosis_H37Rv ---------------------------MDQDRSDNTA-LRRGLRIALRGR
MMAR_3034|M.marinum_M MGGLAPRTVVAVVFAVRGSPSKISILPGVQDRLDGVAGSRRGLRIALRGR
MUL_2274|M.ulcerans_Agy99 ----------------------------MQDRLDGVAGSRRGLRIALRGR
MSMEG_3459|M.smegmatis_MC2_155 ----------------------------------------------MRGH
TH_0424|M.thermoresistible__bu ---------------------------MTQDRSTGRARLRGGLRLALRGT
MAB_1627|M.abscessus_ATCC_1997 -------------------------------------MTSAGADEPVLDL
: .
Mvan_5838|M.vanbaalenii_PYR-1 RDPASGAGQR-RRTSGRLSERHTRKVLDLTIRLAEVMLSSGSGTADVVAT
Mflv_0954|M.gilvum_PYR-GCK RDPATGAGQRSRRPQNTSDERHTRKVLDLTVRLAEVMLSAGSGSADVVAT
Mb3764|M.bovis_AF2122/97 RDPLPVAGRRSRTSGG-IGDLHTRKVLDLTIRLAEVMLSSGSGTADVVAT
Rv3737|M.tuberculosis_H37Rv RDPLPVAGRRSRTSGG-IDDLHTRKVLDLTIRLAEVMLSSGSGTADVVAT
MMAR_3034|M.marinum_M RDPVPVAGQRSRTSSG-MGDQHVRKVLDLTIRLAEVMLSSGSGTADVVAT
MUL_2274|M.ulcerans_Agy99 RDPVPVAGQRSRTSSG-MGDQHVRKVLDLTIRLAEVMLSSGSGTADVVAT
MSMEG_3459|M.smegmatis_MC2_155 RDPAPVAGQRSRASAG-MGDLHTRKVLDLVIRLAEVMLSSGSGTADVVAT
TH_0424|M.thermoresistible__bu RDPAPGAGQR-RAAGG-LDELHTRKVLDLTIRLAEVMLSSGSGTADVVAT
MAB_1627|M.abscessus_ATCC_1997 RLVPPALAAWAATATGILWPTGYFTAAALGIGAIWVRLSRRRWNGAVAAA
* . . . . .. * : * ** .. *.*:
Mvan_5838|M.vanbaalenii_PYR-1 AQDVAQAYQLTDCVVDVFVTTIFVSALPTADSPPVTIVRAVQARSTDYTR
Mflv_0954|M.gilvum_PYR-GCK AQDVAQAYRLNDCVVDVFVTTVFVSAPPTTESPAVTIVRSVRARSTDYSR
Mb3764|M.bovis_AF2122/97 AQDVAQAYQLTDCVVDITVTTIIVSALATTDTPPVTIMRSVRTRSTDYSR
Rv3737|M.tuberculosis_H37Rv AQDVAQAYQLTDCVVDITVTTIIVSALATTDTPPVTIMRSVRTRSTDYSR
MMAR_3034|M.marinum_M ANDVAQAYQITDCVVDITVTTIIVSALPTAESAPVTIVRSVRTRSTNFTR
MUL_2274|M.ulcerans_Agy99 ANDVAQAYQITDCVVDITVTTIIVSALPTAESTPVTIVRSVRTRSTNFTR
MSMEG_3459|M.smegmatis_MC2_155 AQDVAQAYRLTDCVVDITFTTIIVSAPPTADSPPLTIMRAVRTRSTDYTR
TH_0424|M.thermoresistible__bu AQDVAEAYQIKDCVVDITFTTIIVSALPNADHPPVTIVRSVRTRSTDFTR
MAB_1627|M.abscessus_ATCC_1997 VASILIAGMGFSVAAAIRHHGVQNHPLRSR----VGQIVTAQLRVTDDPR
. .: * . .. : : . . : : :.: * *: .*
Mvan_5838|M.vanbaalenii_PYR-1 LADLDRLVRRITSGGVSVDEAHEAMDELSEQPHPYPRWIATAGWAGFALG
Mflv_0954|M.gilvum_PYR-GCK LAALDELVRRITSGGVSVDQAHDAMDELSERPHPYPRWVATAGWAGFALG
Mb3764|M.bovis_AF2122/97 LAELDRLVQRITSGGVAVDQAHEAMDELTERPHPYPRWLATAGAAGFALG
Rv3737|M.tuberculosis_H37Rv LAELDRLVQRITSGGVAVDQAHEAMDELTERPHPYPRWLATAGAAGFALG
MMAR_3034|M.marinum_M LAELDRLVQEITAGGVTVDEAHEAMDELTQRPHPYPRWLATVCWAGFSLG
MUL_2274|M.ulcerans_Agy99 LAELDRLVQEITAGGVTVDEAHEAMDELTQRPHPYPRWLATVCWAGFSLG
MSMEG_3459|M.smegmatis_MC2_155 LAELDALIRDITSGGVSVDQAHAAMDVVTERPHPYPRWLSTAGWAGFALG
TH_0424|M.thermoresistible__bu LAALDRLVREITSGGVSVHQAHEAMDELSEQPHPYPRWLATAGWAGFAFG
MAB_1627|M.abscessus_ATCC_1997 SVTGGRAMMRADLVGLGDPVQGMTGAVLVFGSSSLLGRVAVGDTVRARAA
. . : *: : : . . ::. . .
Mvan_5838|M.vanbaalenii_PYR-1 IAMLLGGTWLTCILAAGTSVLIDRSGRLLNRVG--TPMFFQQAAGASIAT
Mflv_0954|M.gilvum_PYR-GCK IAILLGGNWLVCLLAAATSAVIDQTGRRLNRAG--TPLFFQQVAGALIAT
Mb3764|M.bovis_AF2122/97 VAMLLGGTWLTCVLAAVTSGVIDRLGRLLNRIG--TPLFFQRVFGAGIAT
Rv3737|M.tuberculosis_H37Rv VAMLLGGTWLTCVLAAVTSGVIDRLGRLLNRIG--TPLFFQRVFGAGIAT
MMAR_3034|M.marinum_M IAMMLGANWRTCAIAALTAATIDRLGRVLNRIG--TPYFFQRVTGAAVAT
MUL_2274|M.ulcerans_Agy99 IAMMLGANWRTCAIAALTAATIDRLGRVLNRIG--TPYFFQRVTGAAVAT
MSMEG_3459|M.smegmatis_MC2_155 IAMLLGGSWLTCLVAALTSAAIDRTGRVLNRIG--TPFFFQNVVGAAIAT
TH_0424|M.thermoresistible__bu IAMLMGGTWVTCFLAAFTSAVIDRVNRLLNRAG--TPFFFQQVVGATIAT
MAB_1627|M.abscessus_ATCC_1997 VARPGRRDLTVATLTVVAEPSIFGHSPIHGVANGIRDRFVDVSRNALPAG
:* .. ::. : * . . . *.: .* *
Mvan_5838|M.vanbaalenii_PYR-1 LVAVAAFLFAGQGPTTLVATGIVMLLAGMTLVGSVQDALTGYMLTAVARL
Mflv_0954|M.gilvum_PYR-GCK LVAVAAYRLAGLGPTALVATGIVMLLSGMTLVGSVQDALTGYMITAAARL
Mb3764|M.bovis_AF2122/97 LVAVAAYLIAGQDPTALVATGIVVLLSGMTLVGSMQDAVTGYMLTALARL
Rv3737|M.tuberculosis_H37Rv LVAVAAYLIAGQDPTALVATGIVVLLSGMTLVGSMQDAVTGYMLTALARL
MMAR_3034|M.marinum_M LVAVAAYLFTGEGLAALVATGIVMLLSGLTLVGAMQDAITGYMVTAVARI
MUL_2274|M.ulcerans_Agy99 LVAVAAYLFTGEGLAALVATGIVMLLSGLTLVGAMQDAITGYMVTAVARI
MSMEG_3459|M.smegmatis_MC2_155 LVAVAAYLVTGEGLTALVATGIVMLLSGLTLVGSVQDAITGHMITAVARL
TH_0424|M.thermoresistible__bu VVAVAAYQYAGQGVTTLVATGIVVLLAGLTLVGSMQDALTGHMITALARL
MAB_1627|M.abscessus_ATCC_1997 EAALLPGLVLGDTSALDAQTVAMFRTSGLTHLMAVSGANVSIVCGAVLLL
.*: . * : . * :. :*:* : ::..* .. : * :
Mvan_5838|M.vanbaalenii_PYR-1 GDVLFLTLGIVVGILAGLQIAALAGIQIQLRVDATEYFVVPTTPRQIVVA
Mflv_0954|M.gilvum_PYR-GCK GEVLFLTAGIVVGILAGLQVASLAGITIELQVDATEIMVLPNQPASIAWA
Mb3764|M.bovis_AF2122/97 GDALFLTAGIVVGILISLRGVTNAGIQIELHVDATTTLATPGMPLPILVA
Rv3737|M.tuberculosis_H37Rv GDALFLTAGIVVGILISLRGVTNAGIQIELHVDATTTLATPGMPLPILVA
MMAR_3034|M.marinum_M GEALFLTSGIVVGILAGLQIAKTAGVEIELRVHGSGGFVVPQGPLPILLT
MUL_2274|M.ulcerans_Agy99 GEALFLTSGIVVGILAGLQIAKTAGVEIELRVHGSGGFVVPQGPLPILLT
MSMEG_3459|M.smegmatis_MC2_155 SEALFMTAGIVVGILAGLQIATVAGVTIQLNVDATQAFVTPYRPGPIVLA
TH_0424|M.thermoresistible__bu GDAVFLTAGIVVGILAGLQIASLAGVEIQLRVDVGQTFVVPTEPRTITVA
MAB_1627|M.abscessus_ATCC_1997 GRLIGLRTSVVLAGLVLVGFVILVRPSPSVLRAAVMGAIGLLGVLTARRR
. : : .:*:. * : . . .:
Mvan_5838|M.vanbaalenii_PYR-1 VSGAALAGACLVIASYAKWRSVLTAGVAAGLAEAVLIGLGRAGVGQVVAT
Mflv_0954|M.gilvum_PYR-GCK VFGATVAGACLTIASYARLRAVATAGLAAGLAELVLIALWSGGLGSVIAT
Mb3764|M.bovis_AF2122/97 VSGAALSGVCLTIASYAPLRSVATAGLSAGLAELVLIGLGAAGFGRVVAT
Rv3737|M.tuberculosis_H37Rv VSGAALSGVCLTIASYAPLRSVATAGLSAGLAELVLIGLGAAGFGRVVAT
MMAR_3034|M.marinum_M VLGAMLAGACLTVASYAPLRSAVTAGFAAGLADLVLIGLGTAGFGQVIAT
MUL_2274|M.ulcerans_Agy99 VLGAMLAGACLTVASYAPLRSAVTAGFAAGLADLVLIGLGTAGFGQVIAT
MSMEG_3459|M.smegmatis_MC2_155 VIGAAFASVCLTIASYAPWRTLLPAGLAAGFAEVVLIGLGWAGFGQVVAT
TH_0424|M.thermoresistible__bu IVGSALAGICLTIACYTPMRSAPMTGVAAALATVVIFGVGAAGLGQIMAT
MAB_1627|M.abscessus_ATCC_1997 QAIPALAATILVLLAVSPGLAVDIGFALSVVATAALVVLAPRWSMRLTAR
. .:. *.: . : : : .* .:. : : *
Mvan_5838|M.vanbaalenii_PYR-1 GTAAVGVGLLATLISIRRQAPALVTATAGITPMLPGMAVFRAVFYFAVER
Mflv_0954|M.gilvum_PYR-GCK GCAAVGVGFLATLISIRRQAPALVTATAGITPMLPGMAVFRAVFYFAVEK
Mb3764|M.bovis_AF2122/97 WTAAIGVGFLATLISIRRQAPALVTATAGIMPMLPGLAVFRAVFAFAVND
Rv3737|M.tuberculosis_H37Rv WTAAIGVGFLATLISIRRQAPALVTATAGIMPMLPGLAVFRAVFAFAVND
MMAR_3034|M.marinum_M GIAAVGVGFLATLISIRRQALALVTATAGIVPMLPGLAVFRAVFYFAADS
MUL_2274|M.ulcerans_Agy99 GIAAVGVGFLATLISIRRQALALVTATAGIVPMLPGLAVFRAVFYFAADS
MSMEG_3459|M.smegmatis_MC2_155 GVAAVGVGLFATLLSIRRQAPALVTSTAGITPMLPGMAVFRAVYFFAVED
TH_0424|M.thermoresistible__bu FVAAISVGLLATLVSIRRQAPALVIATAGITPLLPGLAVFRAVFAFAVEG
MAB_1627|M.abscessus_ATCC_1997 GWPKPLADALCVAVAAQLVTAPVIAAISGSVSMASIAANVLAGLVIVPIT
. .. :.. :: : : .:: : :* .: . * . * :.
Mvan_5838|M.vanbaalenii_PYR-1 DFAAGMAQALAAAATALAIGAGVVMGELAGSPLRYRAGRISDFLRVEGPP
Mflv_0954|M.gilvum_PYR-GCK DFAAGMTQAMVAAATALAIGAGVVMGELLGSPLRYRAGRIGQFLQVQGPP
Mb3764|M.bovis_AF2122/97 TPDGGLTQLLEAAATALALGSGVVLGEFLASPLRYGAGRIGDLFRIEGPP
Rv3737|M.tuberculosis_H37Rv TPDGGLTQLLEAAATALALGSGVVLGEFLASPLRYGAGRIGDLFRIEGPP
MMAR_3034|M.marinum_M HFDEAQSQLLSAAATALALGSGVVLGEFVGSPLRYRAGRIGHLLRIEGPP
MUL_2274|M.ulcerans_Agy99 HFDEAQSQLLSAAATALALGSGVVLGEFVGSPLRYRAGRIGHLLRIEGPP
MSMEG_3459|M.smegmatis_MC2_155 RFGDGLAQLLAAGATALALGAGVVLGEFIGSPLRYRAGRVGDFFRIEGPP
TH_0424|M.thermoresistible__bu RFNDGLAQLMTASAIALGIGSGVVLGELVGSPLRYGAGRVGAFFRKDGPP
MAB_1627|M.abscessus_ATCC_1997 VLG-----TAAAALTVVSPQVAGLLARFCG-PELWWLLRVADYASAGGTT
*. .:. . ::..: . * : *:. *..
Mvan_5838|M.vanbaalenii_PYR-1 GLRRAVGNVVALRPAADQQSS-RSPHQRSWSVALEPEL---------SEV
Mflv_0954|M.gilvum_PYR-GCK GLRRAVGRVVRLGPAEDQDATPASPYQRSWSVALEPLP---------AEP
Mb3764|M.bovis_AF2122/97 GLRRAVGRVVRLQPAKSQQPT-GTGGQRWRSVALEPTT---------ADD
Rv3737|M.tuberculosis_H37Rv GLRRAVGRVVRLQPAKSQQPT-GTGGQRWRSVALEPTT---------ADD
MMAR_3034|M.marinum_M GLRRAVGRVVRLEPTKNAQST-NTRGQQSRSVALEPAS---------TDH
MUL_2274|M.ulcerans_Agy99 GLRRAVGRVVRLEPTKNAQST-NTRGQQSRSVALEPAS---------TDH
MSMEG_3459|M.smegmatis_MC2_155 GLRRAVGRVVRLRPAEDAPIT-GPLRRPIESVALEPEP---------TPS
TH_0424|M.thermoresistible__bu GLRRGVGRVVRLRPSPAAPPQAGKLEPRLRSLPLEPESEIEAEDAQADRP
MAB_1627|M.abscessus_ATCC_1997 AIPVPAG-VLGFAVVAVLLGIAVWLWRRRWFRGLVWTG-------VLCAL
.: .* *: : *
Mvan_5838|M.vanbaalenii_PYR-1 ATEANGEDPA-----------------PERDATGER----------
Mflv_0954|M.gilvum_PYR-GCK ALEGSHTDTP-----------------GTEDAPDAT----------
Mb3764|M.bovis_AF2122/97 VDAGYRGDWP-----------------ATCTSATEVR---------
Rv3737|M.tuberculosis_H37Rv VDAGYRGDWP-----------------ATCTSATEVR---------
MMAR_3034|M.marinum_M SDAAEDNDRT-----------------GGHGGHGGHGGHRDES---
MUL_2274|M.ulcerans_Agy99 SDAAEDNDRT-----------------GGHGGHGGHGGHRDES---
MSMEG_3459|M.smegmatis_MC2_155 TTGDESEDTP-----------------RQDGGG-------------
TH_0424|M.thermoresistible__bu AAEAEPDDRPDSERPQPQDRLEDRADPGADDGAGQEPGKNGEPPDR
MAB_1627|M.abscessus_ATCC_1997 ALMISARVVS------------------------------------
.