For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
RGHRDPAPVAGQRSRASAGMGDLHTRKVLDLVIRLAEVMLSSGSGTADVVATAQDVAQAYRLTDCVVDIT FTTIIVSAPPTADSPPLTIMRAVRTRSTDYTRLAELDALIRDITSGGVSVDQAHAAMDVVTERPHPYPRW LSTAGWAGFALGIAMLLGGSWLTCLVAALTSAAIDRTGRVLNRIGTPFFFQNVVGAAIATLVAVAAYLVT GEGLTALVATGIVMLLSGLTLVGSVQDAITGHMITAVARLSEALFMTAGIVVGILAGLQIATVAGVTIQL NVDATQAFVTPYRPGPIVLAVIGAAFASVCLTIASYAPWRTLLPAGLAAGFAEVVLIGLGWAGFGQVVAT GVAAVGVGLFATLLSIRRQAPALVTSTAGITPMLPGMAVFRAVYFFAVEDRFGDGLAQLLAAGATALALG AGVVLGEFIGSPLRYRAGRVGDFFRIEGPPGLRRAVGRVVRLRPAEDAPITGPLRRPIESVALEPEPTPS TTGDESEDTPRQDGGG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3459 | - | - | 100% (507) | hypothetical protein MSMEG_3459 |
| M. smegmatis MC2 155 | MSMEG_3837 | - | 3e-14 | 26.10% (341) | hypothetical protein MSMEG_3837 |
| M. smegmatis MC2 155 | MSMEG_6216 | - | 7e-05 | 28.63% (248) | integral membrane protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3764 | - | 0.0 | 72.42% (504) | transmembrane protein |
| M. gilvum PYR-GCK | Mflv_0954 | - | 0.0 | 70.24% (504) | hypothetical protein Mflv_0954 |
| M. tuberculosis H37Rv | Rv3737 | - | 0.0 | 72.22% (504) | transmembrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0256c | - | 1e-07 | 22.10% (448) | hypothetical protein MAB_0256c |
| M. marinum M | MMAR_3034 | - | 0.0 | 71.20% (507) | transmembrane protein |
| M. avium 104 | MAV_2919 | snm | 1e-06 | 23.35% (257) | secretion protein Snm4 |
| M. thermoresistible (build 8) | TH_0424 | - | 0.0 | 70.90% (488) | PROBABLE CONSERVED TRANSMEMBRANE PROTEIN |
| M. ulcerans Agy99 | MUL_2274 | - | 0.0 | 71.20% (507) | transmembrane protein |
| M. vanbaalenii PYR-1 | Mvan_5838 | - | 0.0 | 71.65% (508) | hypothetical protein Mvan_5838 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3764|M.bovis_AF2122/97 ---------------------------MDQDRSDNTA-LRRGLRIALRGR
Rv3737|M.tuberculosis_H37Rv ---------------------------MDQDRSDNTA-LRRGLRIALRGR
MMAR_3034|M.marinum_M MGGLAPRTVVAVVFAVRGSPSKISILPGVQDRLDGVAGSRRGLRIALRGR
MUL_2274|M.ulcerans_Agy99 ----------------------------MQDRLDGVAGSRRGLRIALRGR
MSMEG_3459|M.smegmatis_MC2_155 ----------------------------------------------MRGH
Mflv_0954|M.gilvum_PYR-GCK ---MLPSPMVPSRQPRTPVPFRRASVSWPPMEPDSTPRFRRGLRIAMRGR
Mvan_5838|M.vanbaalenii_PYR-1 --------MGSDR-------------------SDGMARRRRALHFALKGR
TH_0424|M.thermoresistible__bu ---------------------------MTQDRSTGRARLRGGLRLALRGT
MAB_0256c|M.abscessus_ATCC_199 --------------------------------MTALPRRGRALALVRKTL
MAV_2919|M.avium_104 ---------------------MTAVVEVPQPDVEGISQPQAVVVGVMAGA
Mb3764|M.bovis_AF2122/97 RD-PLPVAGRRSRTSGG-IGDLHTRKVLDLTIRLAEVMLSSGSGTADVVA
Rv3737|M.tuberculosis_H37Rv RD-PLPVAGRRSRTSGG-IDDLHTRKVLDLTIRLAEVMLSSGSGTADVVA
MMAR_3034|M.marinum_M RD-PVPVAGQRSRTSSG-MGDQHVRKVLDLTIRLAEVMLSSGSGTADVVA
MUL_2274|M.ulcerans_Agy99 RD-PVPVAGQRSRTSSG-MGDQHVRKVLDLTIRLAEVMLSSGSGTADVVA
MSMEG_3459|M.smegmatis_MC2_155 RD-PAPVAGQRSRASAG-MGDLHTRKVLDLVIRLAEVMLSSGSGTADVVA
Mflv_0954|M.gilvum_PYR-GCK RD-PATGAGQRSRRPQNTSDERHTRKVLDLTVRLAEVMLSAGSGSADVVA
Mvan_5838|M.vanbaalenii_PYR-1 RD-PASGAGQR-RRTSGRLSERHTRKVLDLTIRLAEVMLSSGSGTADVVA
TH_0424|M.thermoresistible__bu RD-PAPGAGQR-RAAGG-LDELHTRKVLDLTIRLAEVMLSSGSGTADVVA
MAB_0256c|M.abscessus_ATCC_199 KDKPVPLADAR---------HFPDAEVVTMLRMLGIAMLEVGQPTNLVLA
MAV_2919|M.avium_104 GVQIGVLLDAN--APVSVMTEPLLKVVNSRLRELGETPLEATGRGRWALC
. . . * *. . *. .:.
Mb3764|M.bovis_AF2122/97 TAQDVAQAYQLTDCVVDITVT-TIIVSALATTDTPPVTIMRSVRTRSTDY
Rv3737|M.tuberculosis_H37Rv TAQDVAQAYQLTDCVVDITVT-TIIVSALATTDTPPVTIMRSVRTRSTDY
MMAR_3034|M.marinum_M TANDVAQAYQITDCVVDITVT-TIIVSALPTAESAPVTIVRSVRTRSTNF
MUL_2274|M.ulcerans_Agy99 TANDVAQAYQITDCVVDITVT-TIIVSALPTAESTPVTIVRSVRTRSTNF
MSMEG_3459|M.smegmatis_MC2_155 TAQDVAQAYRLTDCVVDITFT-TIIVSAPPTADSPPLTIMRAVRTRSTDY
Mflv_0954|M.gilvum_PYR-GCK TAQDVAQAYRLNDCVVDVFVT-TVFVSAPPTTESPAVTIVRSVRARSTDY
Mvan_5838|M.vanbaalenii_PYR-1 TAQDVAQAYQLTDCVVDVFVT-TIFVSALPTADSPPVTIVRAVQARSTDY
TH_0424|M.thermoresistible__bu TAQDVAEAYQIKDCVVDITFT-TIIVSALPNADHPPVTIVRSVRTRSTDF
MAB_0256c|M.abscessus_ATCC_199 KLHDIAPQYTDKELRAVVLPT-VLIIQIDGVTG--QLEVEESTRN-TAQL
MAV_2919|M.avium_104 LVDGSPLRATQSLSEQDVYDGDRLWIRFIPDTEHRSQVIEHISTAVAANL
.. . . : : : : : . :::
Mb3764|M.bovis_AF2122/97 SR-LAELDRLVQRITSGGVAVDQAHEAMDELTERPHPYPRWLATAGA---
Rv3737|M.tuberculosis_H37Rv SR-LAELDRLVQRITSGGVAVDQAHEAMDELTERPHPYPRWLATAGA---
MMAR_3034|M.marinum_M TR-LAELDRLVQEITAGGVTVDEAHEAMDELTQRPHPYPRWLATVCW---
MUL_2274|M.ulcerans_Agy99 TR-LAELDRLVQEITAGGVTVDEAHEAMDELTQRPHPYPRWLATVCW---
MSMEG_3459|M.smegmatis_MC2_155 TR-LAELDALIRDITSGGVSVDQAHAAMDVVTERPHPYPRWLSTAGW---
Mflv_0954|M.gilvum_PYR-GCK SR-LAALDELVRRITSGGVSVDQAHDAMDELSERPHPYPRWVATAGW---
Mvan_5838|M.vanbaalenii_PYR-1 TR-LADLDRLVRRITSGGVSVDEAHEAMDELSEQPHPYPRWIATAGW---
TH_0424|M.thermoresistible__bu TR-LAALDRLVREITSGGVSVHQAHEAMDELSEQPHPYPRWLATAGW---
MAB_0256c|M.abscessus_ATCC_199 DQ-AGHIDAIADMAVVGAIAPADAIARIYEIRCLKPRFGTVLTVVGH---
MAV_2919|M.avium_104 SKRFAAIDPVVAVQVGATMVAVGVTAASGLLGWWRWHHNSWLPTVYAGVI
: . :* : . . : . : . :...
Mb3764|M.bovis_AF2122/97 AGFALGVAMLLGG------TWLTCVLAAVTSGVIDRLGRLLNRIGTPLFF
Rv3737|M.tuberculosis_H37Rv AGFALGVAMLLGG------TWLTCVLAAVTSGVIDRLGRLLNRIGTPLFF
MMAR_3034|M.marinum_M AGFSLGIAMMLGA------NWRTCAIAALTAATIDRLGRVLNRIGTPYFF
MUL_2274|M.ulcerans_Agy99 AGFSLGIAMMLGA------NWRTCAIAALTAATIDRLGRVLNRIGTPYFF
MSMEG_3459|M.smegmatis_MC2_155 AGFALGIAMLLGG------SWLTCLVAALTSAAIDRTGRVLNRIGTPFFF
Mflv_0954|M.gilvum_PYR-GCK AGFALGIAILLGG------NWLVCLLAAATSAVIDQTGRRLNRAGTPLFF
Mvan_5838|M.vanbaalenii_PYR-1 AGFALGIAMLLGG------TWLTCILAAGTSVLIDRSGRLLNRVGTPMFF
TH_0424|M.thermoresistible__bu AGFAFGIAMLMGG------TWVTCFLAAFTSAVIDRVNRLLNRAGTPFFF
MAB_0256c|M.abscessus_ATCC_199 TILTLGFGLALAP------TSSALPAYLVLGLIVGVLMLATNPMPTLAAT
MAV_2919|M.avium_104 GVLMLGVSVLLLMRATTQQERRVGDTLLLSSLAPVSVAAAAAPPGGVGSP
: :*..: : . .
Mb3764|M.bovis_AF2122/97 QRVFGAGIATLVAVAAYL-IAGQDPTALVATGIVVLLSGMTLVGSMQDAV
Rv3737|M.tuberculosis_H37Rv QRVFGAGIATLVAVAAYL-IAGQDPTALVATGIVVLLSGMTLVGSMQDAV
MMAR_3034|M.marinum_M QRVTGAAVATLVAVAAYL-FTGEGLAALVATGIVMLLSGLTLVGAMQDAI
MUL_2274|M.ulcerans_Agy99 QRVTGAAVATLVAVAAYL-FTGEGLAALVATGIVMLLSGLTLVGAMQDAI
MSMEG_3459|M.smegmatis_MC2_155 QNVVGAAIATLVAVAAYL-VTGEGLTALVATGIVMLLSGLTLVGSVQDAI
Mflv_0954|M.gilvum_PYR-GCK QQVAGALIATLVAVAAYR-LAGLGPTALVATGIVMLLSGMTLVGSVQDAL
Mvan_5838|M.vanbaalenii_PYR-1 QQAAGASIATLVAVAAFL-FAGQGPTTLVATGIVMLLAGMTLVGSVQDAL
TH_0424|M.thermoresistible__bu QQVVGATIATVVAVAAYQ-YAGQGVTTLVATGIVVLLAGLTLVGSMQDAL
MAB_0256c|M.abscessus_ATCC_199 MPAVAAFVVTVISTLIVANVPSEGLARVLAPALIAVLPGMTLTIGALELT
MAV_2919|M.avium_104 QAVLGFGVLTIAAVLALR-FTGRRLAIYTAIVTVSAIAALAALARMVAMT
. . : *: :. .. : * : :..::
Mb3764|M.bovis_AF2122/97 TGYMLTALARLGDALFLTAGIVVG-ILISLRGVTNAGIQIELHVDATTTL
Rv3737|M.tuberculosis_H37Rv TGYMLTALARLGDALFLTAGIVVG-ILISLRGVTNAGIQIELHVDATTTL
MMAR_3034|M.marinum_M TGYMVTAVARIGEALFLTSGIVVG-ILAGLQIAKTAGVEIELRVHGSGGF
MUL_2274|M.ulcerans_Agy99 TGYMVTAVARIGEALFLTSGIVVG-ILAGLQIAKTAGVEIELRVHGSGGF
MSMEG_3459|M.smegmatis_MC2_155 TGHMITAVARLSEALFMTAGIVVG-ILAGLQIATVAGVTIQLNVDATQAF
Mflv_0954|M.gilvum_PYR-GCK TGYMITAAARLGEVLFLTAGIVVG-ILAGLQVASLAGITIELQVDATEIM
Mvan_5838|M.vanbaalenii_PYR-1 TGYMLTAVARLGDVLFLTLGIVVG-ILAGLQIAALAGIQIQLRVDATEYF
TH_0424|M.thermoresistible__bu TGHMITALARLGDAVFLTAGIVVG-ILAGLQIASLAGVEIQLRVDVGQTF
MAB_0256c|M.abscessus_ATCC_199 STQLMAGSTRIVYGIAQLMLLALG-VVIGVKVAGPP---------QPSPL
MAV_2919|M.avium_104 GAVTLLTCVVLVSVLIYQSAPAISRRLAGIRLPVFPSATSRWVFEARPDL
: . : : .:. : .:: . :
Mb3764|M.bovis_AF2122/97 ATPGMPLPILVAVSGAALSGVCLTIASYAPLRSVATAGLSAGLAELVLIG
Rv3737|M.tuberculosis_H37Rv ATPGMPLPILVAVSGAALSGVCLTIASYAPLRSVATAGLSAGLAELVLIG
MMAR_3034|M.marinum_M VVPQGPLPILLTVLGAMLAGACLTVASYAPLRSAVTAGFAAGLADLVLIG
MUL_2274|M.ulcerans_Agy99 VVPQGPLPILLTVLGAMLAGACLTVASYAPLRSAVTAGFAAGLADLVLIG
MSMEG_3459|M.smegmatis_MC2_155 VTPYRPGPIVLAVIGAAFASVCLTIASYAPWRTLLPAGLAAGFAEVVLIG
Mflv_0954|M.gilvum_PYR-GCK VLPNQPASIAWAVFGATVAGACLTIASYARLRAVATAGLAAGLAELVLIA
Mvan_5838|M.vanbaalenii_PYR-1 VVPTTPRQIVVAVSGAALAGACLVIASYAKWRSVLTAGVAAGLAEAVLIG
TH_0424|M.thermoresistible__bu VVPTEPRTITVAIVGSALAGICLTIACYTPMRSAPMTGVAAALATVVIFG
MAB_0256c|M.abscessus_ATCC_199 GPPLGSWTIALAVPVIAVG---FYLYKSAPRGSLIWLVLAIGVAMLGQR-
MAV_2919|M.avium_104 PTTVVRSDGGPPVLEGPAS--VRDVLTQAERARSFLSGLLIGLGVLMVVS
. .: . : : . ...
Mb3764|M.bovis_AF2122/97 LGAAGFGRVVATWTAAIGVGFLATLISIRRQAP-ALVTATAGIMPMLPGL
Rv3737|M.tuberculosis_H37Rv LGAAGFGRVVATWTAAIGVGFLATLISIRRQAP-ALVTATAGIMPMLPGL
MMAR_3034|M.marinum_M LGTAGFGQVIATGIAAVGVGFLATLISIRRQAL-ALVTATAGIVPMLPGL
MUL_2274|M.ulcerans_Agy99 LGTAGFGQVIATGIAAVGVGFLATLISIRRQAL-ALVTATAGIVPMLPGL
MSMEG_3459|M.smegmatis_MC2_155 LGWAGFGQVVATGVAAVGVGLFATLLSIRRQAP-ALVTSTAGITPMLPGM
Mflv_0954|M.gilvum_PYR-GCK LWSGGLGSVIATGCAAVGVGFLATLISIRRQAP-ALVTATAGITPMLPGM
Mvan_5838|M.vanbaalenii_PYR-1 LGRAGVGQVVATGTAAVGVGLLATLISIRRQAP-ALVTATAGITPMLPGM
TH_0424|M.thermoresistible__bu VGAAGLGQIMATFVAAISVGLLATLVSIRRQAP-ALVIATAGITPLLPGL
MAB_0256c|M.abscessus_ATCC_199 LGSLFLAPAMTGFVGAVAVVPFALFAARFKGAPSAIVLLLAAFWCLVPGA
MAV_2919|M.avium_104 LTALSDPRTGQRWLPVLLAGFCAGFLLLRGRSYVDRWQAITLAGTAVLIV
: .: . * : : : :
Mb3764|M.bovis_AF2122/97 AVFRAVFAFAVNDTPDGGLTQLLEAAATALALGSGVVLGEFLASPLRYGA
Rv3737|M.tuberculosis_H37Rv AVFRAVFAFAVNDTPDGGLTQLLEAAATALALGSGVVLGEFLASPLRYGA
MMAR_3034|M.marinum_M AVFRAVFYFAADSHFDEAQSQLLSAAATALALGSGVVLGEFVGSPLRYRA
MUL_2274|M.ulcerans_Agy99 AVFRAVFYFAADSHFDEAQSQLLSAAATALALGSGVVLGEFVGSPLRYRA
MSMEG_3459|M.smegmatis_MC2_155 AVFRAVYFFAVEDRFGDGLAQLLAAGATALALGAGVVLGEFIGSPLRYRA
Mflv_0954|M.gilvum_PYR-GCK AVFRAVFYFAVEKDFAAGMTQAMVAAATALAIGAGVVMGELLGSPLRYRA
Mvan_5838|M.vanbaalenii_PYR-1 AVFRAVFYFAVERDFAAGMAQALAAAATALAIGAGVVMGELAGSPLRYRA
TH_0424|M.thermoresistible__bu AVFRAVFAFAVEGRFNDGLAQLMTASAIALGIGSGVVLGELVGSPLRYGA
MAB_0256c|M.abscessus_ATCC_199 LSFVNVSEVAATGHAN--LTALLDTCMAIFSIALGLLVGASLHRGMRYAL
MAV_2919|M.avium_104 GAVVVRYALVLQSPLAVSISAAILVLVPVAGLTSAAVVPNTVYSPLFRKF
. .. : : . .: . :: :
Mb3764|M.bovis_AF2122/97 GRIGDLFRIEGPPGLRRAVGRVVRLQPAKSQQPT-GTGGQRWRSVALEPT
Rv3737|M.tuberculosis_H37Rv GRIGDLFRIEGPPGLRRAVGRVVRLQPAKSQQPT-GTGGQRWRSVALEPT
MMAR_3034|M.marinum_M GRIGHLLRIEGPPGLRRAVGRVVRLEPTKNAQST-NTRGQQSRSVALEPA
MUL_2274|M.ulcerans_Agy99 GRIGHLLRIEGPPGLRRAVGRVVRLEPTKNAQST-NTRGQQSRSVALEPA
MSMEG_3459|M.smegmatis_MC2_155 GRVGDFFRIEGPPGLRRAVGRVVRLRPAEDAPIT-GPLRRPIESVALEPE
Mflv_0954|M.gilvum_PYR-GCK GRIGQFLQVQGPPGLRRAVGRVVRLGPAEDQDATPASPYQRSWSVALEPL
Mvan_5838|M.vanbaalenii_PYR-1 GRISDFLRVEGPPGLRRAVGNVVALRPAADQQSS-RSPHQRSWSVALEPE
TH_0424|M.thermoresistible__bu GRVGAFFRKDGPPGLRRGVGRVVRLRPSPAAPPQAGKLEPRLRSLPLEPE
MAB_0256c|M.abscessus_ATCC_199 TVSR----------------------------------------------
MAV_2919|M.avium_104 VEWIEYLCLMPIFPLALWLMNVYAAIRYR---------------------
Mb3764|M.bovis_AF2122/97 T---------ADDVDAGYRGDWP-----------------ATCTSATEVR
Rv3737|M.tuberculosis_H37Rv T---------ADDVDAGYRGDWP-----------------ATCTSATEVR
MMAR_3034|M.marinum_M S---------TDHSDAAEDNDRT-----------------GGHGGHGGHG
MUL_2274|M.ulcerans_Agy99 S---------TDHSDAAEDNDRT-----------------GGHGGHGGHG
MSMEG_3459|M.smegmatis_MC2_155 P---------TPSTTGDESEDTP-----------------RQDGGG----
Mflv_0954|M.gilvum_PYR-GCK P---------AEPALEGSHTDTP-----------------GTEDAPDAT-
Mvan_5838|M.vanbaalenii_PYR-1 L---------SEVATEANGEDPA-----------------PERDATGER-
TH_0424|M.thermoresistible__bu SEIEAEDAQADRPAAEAEPDDRPDSERPQPQDRLEDRADPGADDGAGQEP
MAB_0256c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_2919|M.avium_104 --------------------------------------------------
Mb3764|M.bovis_AF2122/97 ---------
Rv3737|M.tuberculosis_H37Rv ---------
MMAR_3034|M.marinum_M GHRDES---
MUL_2274|M.ulcerans_Agy99 GHRDES---
MSMEG_3459|M.smegmatis_MC2_155 ---------
Mflv_0954|M.gilvum_PYR-GCK ---------
Mvan_5838|M.vanbaalenii_PYR-1 ---------
TH_0424|M.thermoresistible__bu GKNGEPPDR
MAB_0256c|M.abscessus_ATCC_199 ---------
MAV_2919|M.avium_104 ---------