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MIAAATRNLRRLLPSRRDYADLPRSWRRDVLAGVTVGVVALPLALAFGISSGVGAAAGLITAVVAGLVAA VFGGSAVQVSGPTGAMAVVLAPIVASHGLGSIALVTLLGGLIVLLAGVTGLGRAVTFIPWPVIEGFTLGI AAIIFLQQVPAAFSATSPPGQRTLTAAWQVVTHADWSQAGKTLGVIAFVAALMLLLPRIHRAIPESLAAV IAATVVVAALGISVATIGELPSHLPAPVLPHADAGALRDLFGAALAIAALAAIESLLSARVAATMAPTGP YDPDRELVGQGLASVASGVFGGMPATGAIARTAVNVRSGARTRLSAVVHSLVLLGVVYLATGPVSAIPLA ALSGVLMVTSFRMISWSTIRKIVTSTRSDALTFVLTAVITVCFDLIEAVEIGILVAAFFALHSVARRSSV VREELPAPYQPGDEEIALLRLDGAMFFGVAERISNAIIDSDHPRTSVVIIRMSQLGMLDATGANTLAQIC TELEARGITVIIKGVRPEHSALLSSVGVFESLRHENHLVDTLDEAIEHARTHAHRQPH
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5693 | - | - | 100% (548) | sulphate transporter |
| M. vanbaalenii PYR-1 | Mvan_1159 | - | 3e-57 | 31.71% (492) | sulphate transporter |
| M. vanbaalenii PYR-1 | Mvan_1430 | - | 2e-38 | 26.49% (555) | sulfate transporter |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1734 | - | 2e-62 | 30.94% (530) | transmembrane protein |
| M. gilvum PYR-GCK | Mflv_1119 | - | 0.0 | 89.81% (540) | sulphate transporter |
| M. tuberculosis H37Rv | Rv1707 | - | 2e-62 | 30.94% (530) | transmembrane protein |
| M. leprae Br4923 | MLBr_02279 | - | 7e-48 | 31.01% (487) | putative transmembrane transport protein |
| M. abscessus ATCC 19977 | MAB_4448 | - | 3e-55 | 29.13% (563) | putative sulfate transporter |
| M. marinum M | MMAR_4750 | - | 8e-54 | 31.12% (498) | integral membrane transporter |
| M. avium 104 | MAV_4578 | - | 3e-50 | 31.13% (485) | carbonate dehydratase |
| M. smegmatis MC2 155 | MSMEG_6453 | - | 0.0 | 82.44% (541) | sulfate permease |
| M. thermoresistible (build 8) | TH_2104 | - | 0.0 | 79.85% (546) | sulfate permease |
| M. ulcerans Agy99 | MUL_0321 | - | 1e-51 | 30.52% (498) | integral membrane transporter |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_5693|M.vanbaalenii_PYR-1 ------MIAAATRNLRRLLPSRRDYADLPRSWRRDVLAGVTVGVVALPLA
Mflv_1119|M.gilvum_PYR-GCK ------MITIGR--LGRLLPQRSDYTDLRRSWRADLLAGVTVGVVALPLA
MSMEG_6453|M.smegmatis_MC2_155 --------MLAN--LARLLPHKNDYTDVPRTWRQDVLAGITVGVVALPLA
TH_2104|M.thermoresistible__bu ------VIATAKENLIRLLPSRRDYAELPRSWRRDILAGITVGVVALPLA
Mb1734|M.bovis_AF2122/97 ---------------------------MLQRIARELLSGVAVAIVALPLA
Rv1707|M.tuberculosis_H37Rv ---------------------------MLQRIARELLSGVAVAIVALPLA
MMAR_4750|M.marinum_M ---------------------MLAALRSPTRLRTEVLAGLVVALALIPEA
MUL_0321|M.ulcerans_Agy99 MSSQQVSAVPTIRKAGDPSTAVLAALRSPTRLRTEVLAGLVVALALIPEA
MLBr_02279|M.leprae_Br4923 ---------------------------MRSAIRYDLPASLVVFLVALPLS
MAV_4578|M.avium_104 --------MQDIQRADDALPTASRAERLRGVIRHDLPSSLVVFLVALPLS
MAB_4448|M.abscessus_ATCC_1997 ----------------MPSAPGLFESYDAIKARRDVIAGLTVAAISLPQA
:: :.:.* :* :
Mvan_5693|M.vanbaalenii_PYR-1 LAFGISSG---VGAAAGLITAVVAGLVAAVFGGSAVQVSGPTGAMAVVLA
Mflv_1119|M.gilvum_PYR-GCK LAFGISSG---VGAAAGLITAVVAGLVAAVFGGSSVQVSGPTGAMAVVLA
MSMEG_6453|M.smegmatis_MC2_155 LAFGISSG---VGAAAGLITAVVAGLVAAVFGGSHVQVSGPTGAMAVVLA
TH_2104|M.thermoresistible__bu LAFGISSG---VGAAAGLITAVVAGLVAAVFGGSHIQVSGPTGAMAVILA
Mb1734|M.bovis_AF2122/97 IAFGITATGTSQGALIGLYGAIFAGFFAAVFGGTPGQVTGPTGPITVVAT
Rv1707|M.tuberculosis_H37Rv IAFGITATGTSQGALIGLYGAIFAGFFAAVFGGTPGQVTGPTGPITVVAT
MMAR_4750|M.marinum_M ISFSIIAG---VDPRVGLFASFTMAVTIAVVGGRPAMISAATGAIALVIA
MUL_0321|M.ulcerans_Agy99 ISFSIIAG---VDPRVGLFASFTMAVTIAVVGGRLAMISAATGAIALVIA
MLBr_02279|M.leprae_Br4923 LGIAIASD---TPVLAGLIAAIVGGIVAGALGGSPLQVSGPAAGLTVVIA
MAV_4578|M.avium_104 LGIAIASN---APVLAGLIAAIVGGIVVGALGGSPLQVSGPAAGLTVVVA
MAB_4448|M.abscessus_ATCC_1997 MAYALIAG---VDPKYGVYSAIVVTAIASIFGSSSHLINGPTSAISLLVF
:. .: : *: :. . .*. :...:. ::::
Mvan_5693|M.vanbaalenii_PYR-1 PIVASHG-------LGSIALVTLLGGLIVLLAGVTGLGRAVTFIPWPVIE
Mflv_1119|M.gilvum_PYR-GCK PIVAMHG-------LGSIALVTVLAGLLVLLAGVTGLGRAVTFIPWPVIE
MSMEG_6453|M.smegmatis_MC2_155 PIVAEHG-------LGSIALVTVLAGLLVLAAGITGLGRAVTFIPWPVIE
TH_2104|M.thermoresistible__bu PIVAQHG-------LTSIALVTVLAGLIVLAAGITGLGRAVTFIPWPVIE
Mb1734|M.bovis_AF2122/97 ATIAEHG-------LEGAFFAFILAGVFQILFGACRLGSLIRYVPHPVIS
Rv1707|M.tuberculosis_H37Rv ATIAEHG-------LEGAFFAFILAGVFQILFGACRLGSLIRYVPHPVIS
MMAR_4750|M.marinum_M PLAREHG-------ADYFIAAVILAGLVQITLSLLGVARLMRFIPRSVMV
MUL_0321|M.ulcerans_Agy99 PLAREQG-------ADYFIAAVILAGLVQITLSLLGVARLMRFIPRSVMV
MLBr_02279|M.leprae_Br4923 DLISDFG-------WGVTCFITVAAGVLQVLLGLSRVARAALAISPVVVH
MAV_4578|M.avium_104 GLVSDFG-------WGVTCFITVAAGAVQVLLGLSRVARAALAISPVVVH
MAB_4448|M.abscessus_ATCC_1997 SSLAFLDPENRTGLFEALFLLGVLVGTIQILIAVFKLGDLTRYISESVVI
. : * . : . :. :. *:
Mvan_5693|M.vanbaalenii_PYR-1 GFTLGIAAIIFLQQVPAAFSATSPPGQRTLTAAWQVVTHAD-----WSQA
Mflv_1119|M.gilvum_PYR-GCK GFTLGIAAIIFLQQIPAAFAAGGPPGERTLPAAWHVVTHAD-----WSEA
MSMEG_6453|M.smegmatis_MC2_155 GFTLGIAAIIFLQQVPAALAQQAPSGERTLLAAFTVVRNAD-----WGEA
TH_2104|M.thermoresistible__bu GFTLGIAAIIFLQQVPAAFATEAPAGQRTLVAAWHVVTHAD-----WTAA
Mb1734|M.bovis_AF2122/97 GFMGGIAILIIMTQLDQVRSS-------SLLVLVTVVLLLA-----SGRF
Rv1707|M.tuberculosis_H37Rv GFMGGIAILIIMTQLDQVRSS-------SLLVLVTVVLLLA-----SGRF
MMAR_4750|M.marinum_M GFVNALAILIFLSQLPHLLGVP----------------------------
MUL_0321|M.ulcerans_Agy99 GFVNALAILIFLSQVPHLLGVP----------------------------
MLBr_02279|M.leprae_Br4923 AMLAGVGITIALQQAHVLLGGKSKSTAWHNAIGLPSQILGA-----HRPG
MAV_4578|M.avium_104 AMLAGIGITIALQQTHVLLGGKSKSTAWHNLIGLPGQIIGA-----HRPG
MAB_4448|M.abscessus_ATCC_1997 GFMASAALLLAIGQLANAIGVRDKGDGHMQVLQRAWLTLFHGDAVNYRAL
.: . . : : * .
Mvan_5693|M.vanbaalenii_PYR-1 GKTLGVIAFVAALMLLLPRIHRAIPESLAAVIAATVVVAALGISVATIG-
Mflv_1119|M.gilvum_PYR-GCK VKSLGVIAFVVALMVALPRIHRAIPESLAAVVGATVAVGVLGISVATIG-
MSMEG_6453|M.smegmatis_MC2_155 AKTLAVVGVVAVLMIVLPRVHSGIPASLTAVIVATVLIVALDIPVATIG-
TH_2104|M.thermoresistible__bu VKTLSVVSLVALLMVVLPRLHRSIPESLTAVVAATVIVTVFGISVATIG-
Mb1734|M.bovis_AF2122/97 IKAIPPSLLVLVLVSSVLPLAAPWLRDLRAGPVS------INRTVDYIG-
Rv1707|M.tuberculosis_H37Rv IKAIPPSLLVLVLVSSVLPLAAPWLRDLRAGPVS------INRTVDYIG-
MMAR_4750|M.marinum_M PVVYPFVIVGLLLMVFLPKLTTVVPAPLVAIVVLTAAAVAFSVEIPNVGD
MUL_0321|M.ulcerans_Agy99 AVVYPFVIVGLLLMVFLPKLTTVVPAPLVAIVVLTAAAVAFSVEILNVGD
MLBr_02279|M.leprae_Br4923 VILGVLVITILIAWRWVPARVARIPGPLVAIVVTTLVSVVFPFHVSRIQ-
MAV_4578|M.avium_104 VLLGVLVIVILVAWRWVPAKVRRVPGPLVAIVAVTVISVVFPFHVRRID-
MAB_4448|M.abscessus_ATCC_1997 FLSVTAVALAVLLRRLVQRYELPQIDMLLVLIVTAVIAYAYGWTVPDGTG
: * . :
Mvan_5693|M.vanbaalenii_PYR-1 --------ELPSHLPAPVLPHA--DAGALRDLFGAALAIAALAAIESLLS
Mflv_1119|M.gilvum_PYR-GCK --------ELPSHLPAPMLPQI--VPGALRDLFGAALAIAALAAIESLLS
MSMEG_6453|M.smegmatis_MC2_155 --------ELPSHLPAPVLPHV--DVNTLRTMFSAALAIAALAAIESLLS
TH_2104|M.thermoresistible__bu --------ELPSQLPTPVLPQA--DMGAMQTLLGAALAIAALAAIESLLS
Mb1734|M.bovis_AF2122/97 --------EIPQAMPSFDFPQV--ANSTMLQVLLSAVAIALLGSLDSLLT
Rv1707|M.tuberculosis_H37Rv --------EIPQAMPSFDFPQV--ANSTMLQVLLSAVAIALLGSLDSLLT
MMAR_4750|M.marinum_M E------GQLPSSLPTLLVPHVPFALETLSIIGPYALAMALVGLLESLLT
MUL_0321|M.ulcerans_Agy99 E------GQLPSSLPTLLVPHVPFALETLSIIGPYALAMALVGLLESLLT
MLBr_02279|M.leprae_Br4923 -------VDNRSSLDVLQLPKLP--DGHWGAVVLGVITVALIASVESLLS
MAV_4578|M.avium_104 -------LDG-SPLDALQLPDLP--HGNWSGVAVGVITVALIASVESLLS
MAB_4448|M.abscessus_ATCC_1997 HTDVKISGKIPASLPEFHIPEVQ--VSTLGELSHGALAIAFIGLIEALSI
. : .*. : .:::* :. :::*
Mvan_5693|M.vanbaalenii_PYR-1 ARVAATMAPTGPYDPDRELVGQGLASVASGVFGGMPATGAIARTAVNVRS
Mflv_1119|M.gilvum_PYR-GCK ARVAATMAPTGPYDPDRELVGQGLASVASGAFGGMPATGAIARTAVNVRS
MSMEG_6453|M.smegmatis_MC2_155 ARVAATMSPTGPYDPNRELVGQGLASVASGAFGGMPATGAIARTAVNVRS
TH_2104|M.thermoresistible__bu ARVAATMSATGPYHPDRELVGQGMASVASGLFGGMPATGAIARTAVNVRS
Mb1734|M.bovis_AF2122/97 SLVMDNIRGTR-HRSNKELIGQGIGNIAAGLFGGLAGAGATVRSVVNVRN
Rv1707|M.tuberculosis_H37Rv SLVMDNIRGTR-HRSNKELIGQGIGNIAAGLFGGLSGAGATVRSVVNVRN
MMAR_4750|M.marinum_M AKLVDDITDTHSNKTR-EAWGQGVANVVTGFFGGMGGCAMIGQTMINVKV
MUL_0321|M.ulcerans_Agy99 AKLVDDITDTHSNKTR-EAWGQGVANVVTGFFGGMGGCAMIGQTMINVKV
MLBr_02279|M.leprae_Br4923 AVSLDKMHNGPRTDLNRELIGQGAANIVSGAIGGLPITGVIVRSSTNVIA
MAV_4578|M.avium_104 AVSVDRMHNGPRTDFNRELVGQGAANMISGAVGGLPVTGVIVRSSTNVNA
MAB_4448|M.abscessus_ATCC_1997 AKAIAHHTGQQ-IDYNRQILAEGLANLAGGFFQSLPGSGSLSRSAINYQS
: : .:* ..: * . .: . :: *
Mvan_5693|M.vanbaalenii_PYR-1 -GARTRLSAVVHSLVLLGVVYLATGPVSAIPLAALSGVLMVTSFRMISWS
Mflv_1119|M.gilvum_PYR-GCK -GARTRLAAVVHSVVLLGVVYLATGPVAAIPLAALSGVLMVTSFRMISRS
MSMEG_6453|M.smegmatis_MC2_155 -GAATRLSAIVHSLVLLAVVYLATGPVSAIPLSALAGVLMVTSFRMISAT
TH_2104|M.thermoresistible__bu -GARTRLAAIVHSLVLLAVVYLATGPVSAIPLSALAGVLMVTSFRMVSLH
Mb1734|M.bovis_AF2122/97 -GGQTALSAATHSVVLFVFVAGLGAVVQYIPLAVLSGILILVAVGMFDWH
Rv1707|M.tuberculosis_H37Rv -GGQTALSAATHSVVLFVFVAGLGAVVQYIPLAVLSGILILVAVGMFDWH
MMAR_4750|M.marinum_M SGARTRISTFLAGLFLLGLVVGLGDVVALIPMAALVAVMIMVSVGTMDWH
MUL_0321|M.ulcerans_Agy99 PGARTRISTFLAGLFLLGLVVGLGDVVALIPMAALVAVMIMVSVGTMDWH
MLBr_02279|M.leprae_Br4923 -GAKSRASSIMHGIWILLFTIPFAGLVDQIPSAALAGLLIVVGVQLLKPA
MAV_4578|M.avium_104 -GARSRASAIMHGVWILLFTIPFAGLVDEIPTAALAGLLIVIGIQLLKPA
MAB_4448|M.abscessus_ATCC_1997 -GAATRFSGIVSAATVTIALLLFAPLLRYIPQAALAGLLLVTAVRLVDFH
*. : : . : : ** :.* .:::: .. ..
Mvan_5693|M.vanbaalenii_PYR-1 TIR--KIVTSTRSDALTFVLTAVITVCFD-LIEAVEIGILVAAFFALHSV
Mflv_1119|M.gilvum_PYR-GCK TMR--KILTSTRSDATTFVLTAVVTVCFD-LIEAVQIGILVAAFFALRSV
MSMEG_6453|M.smegmatis_MC2_155 TIR--KIVRSTRSDALIFVLTAVITVCFD-LIEAVEIGILVAAFFALRSV
TH_2104|M.thermoresistible__bu TAR--RILRSTRSDALTFVLTALVTITFD-LIEAVQIGVLVAAFFALRNV
Mb1734|M.bovis_AF2122/97 AMR--KAHVSPRGDVIVMFTTMIITVVVD-LTIAVMVGIALSLLVHRLRS
Rv1707|M.tuberculosis_H37Rv AMR--KAHVSPRGDVIVMFTTMIITVVVD-LTIAVMVGIALSLLVHRLRS
MMAR_4750|M.marinum_M SIAPATLRRMPRSETLVMLATVVVTVATHNLAYGVVAGVLTAMVLFARRV
MUL_0321|M.ulcerans_Agy99 SIAPATLRRMPRSETLVMLATVVVTVATHNLAYGVVAGVLTAMVLFARRV
MLBr_02279|M.leprae_Br4923 HIET----ALRNGDLAVYLVTAVCVVFLN-LLHGVMIGLAVAIALTGWRV
MAV_4578|M.avium_104 HIET----AMKHGDLAVYVVTAVSVIFLN-LLHGVMIGLALAIALTGWRV
MAB_4448|M.abscessus_ATCC_1997 RLVY--AIKASRYDAGLVIITALVGVAVN-LDTAVLVGVVLSILLFVPRA
. : . * : : . * .* *: : .
Mvan_5693|M.vanbaalenii_PYR-1 ARRSS---------VVREELPAPYQPGDEEIALLRLDGAMFFGVAERISN
Mflv_1119|M.gilvum_PYR-GCK ARRSS---------VVREELPAPHRPGDEEIALLRLDGAMFFGAAERISN
MSMEG_6453|M.smegmatis_MC2_155 ARRSS---------VVREELPGPRRPGDDQIALLRLDGAMFFGAAERISN
TH_2104|M.thermoresistible__bu ARRSG---------VTREELPGEPQPGDERIALLRLEGSMFFGVAERMSS
Mb1734|M.bovis_AF2122/97 RQRKA---------KVTQDDTG----------TYRIDGPLSFLSVDGVFG
Rv1707|M.tuberculosis_H37Rv RQRKA---------KVTQDDTG----------TYRIDGPLSFLSVDGVFG
MMAR_4750|M.marinum_M AHFMT---------VERIVESDTG--SAAETVVYRVSGELFFASSNDLVY
MUL_0321|M.ulcerans_Agy99 AHFMT---------VERIVESDTG--SAAETVVYRVSCELFFASSNDLVY
MLBr_02279|M.leprae_Br4923 IRARV---------EAQPVGDEWH--------VLVAG-ACTFLALPRLTR
MAV_4578|M.avium_104 IRAKI---------EAAQLDGEWR--------VTIEGAACTFLALPRLTR
MAB_4448|M.abscessus_ATCC_1997 AKLKAAELVVTDEGVIRERTPQDRPTGAGAPVIYDLEGELFFGAAPELDR
: * :
Mvan_5693|M.vanbaalenii_PYR-1 AII----DSDHPRTSVVIIRMSQLGMLDATGANTLAQICTELEARGITVI
Mflv_1119|M.gilvum_PYR-GCK AIV----DGDHPRTSVVIIRMSQLGMLDATGANTLAQICTELEARGITVI
MSMEG_6453|M.smegmatis_MC2_155 AIT----DAEHPHVSVVIIRMSQLGMLDATGAHTLAEITTELESRGITVI
TH_2104|M.thermoresistible__bu TIS----EIEADDISVVIIRLSQLGTLDATGANSLAQIATELERRGITVI
Mb1734|M.bovis_AF2122/97 SLR----DGRED----VSLDLQHVTYLDTSGAQALLYFIDHSEKDGVAVS
Rv1707|M.tuberculosis_H37Rv SLR----DGRED----VSLDLQHVTYLDTSGARALLYFIDHSEKDGVAVS
MMAR_4750|M.marinum_M QFN----YVDDPDN--VVIDMSQSHIWDASTVAALDAIITKYHAKGRCVE
MUL_0321|M.ulcerans_Agy99 QFN----YVDDPDN--VVIDMSQSHIWDASTVAALDAIITKYHAKGRCVE
MLBr_02279|M.leprae_Br4923 VLA----SVPPCTR---VTVNISVNYLDHAAHQAIHDWQRQHHATGGTVH
MAV_4578|M.avium_104 VLA----SVPRGAT---VTVAIAVHYLDHAAHQAITDWQRQQEATGGTVR
MAB_4448|M.abscessus_ATCC_1997 YLESLHTRIRDEHLKVVILRLKRVRHPDVVCIERLEHFIREQQQLGVTVL
: * : . . * *
Mvan_5693|M.vanbaalenii_PYR-1 IKGVRPEHSALLSSVGVFESLRHENHLVDTLDEAIEHARTHAHRQPH---
Mflv_1119|M.gilvum_PYR-GCK IKGVRPEHSALLANVGVFESLRHERHLVDTLDEAIEHARTHARRQPH---
MSMEG_6453|M.smegmatis_MC2_155 IKGVRPEHMDLLANVGVFESLRHENHLLDSLDDAVAHARTHVARQPH---
TH_2104|M.thermoresistible__bu IKGVQPEHSKLLSNVGVFESLRHEKHLIDSLEDAIEHARSHVARQQTART
Mb1734|M.bovis_AF2122/97 IKRIPPRLESQLTALADNEQRDKLRTVLESA-------------------
Rv1707|M.tuberculosis_H37Rv IKRIPPRLESQLTALADNEQRDKLRTVLESA-------------------
MMAR_4750|M.marinum_M IIGLNQDSAERHGRLSGQFGAEH---------------------------
MUL_0321|M.ulcerans_Agy99 IIGLNQDSAERHGRLSGQFGAEH---------------------------
MLBr_02279|M.leprae_Br4923 ING-VVETGHFSRCAMGDLIGPEQQPEAAA--------------------
MAV_4578|M.avium_104 IEGAVVATGRRD-----EPQVEAEMPGAAA--------------------
MAB_4448|M.abscessus_ATCC_1997 LAGVRPDSLALLENVGFTHWLPPEQVFPEEEKEFSATLRAVRYAQSRLEE
:
Mvan_5693|M.vanbaalenii_PYR-1 ----------------
Mflv_1119|M.gilvum_PYR-GCK ----------------
MSMEG_6453|M.smegmatis_MC2_155 ----------------
TH_2104|M.thermoresistible__bu TS--------------
Mb1734|M.bovis_AF2122/97 ----------------
Rv1707|M.tuberculosis_H37Rv ----------------
MMAR_4750|M.marinum_M ----------------
MUL_0321|M.ulcerans_Agy99 ----------------
MLBr_02279|M.leprae_Br4923 ----------------
MAV_4578|M.avium_104 ----------------
MAB_4448|M.abscessus_ATCC_1997 EPPNPAANPEKLYYLV