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M. ulcerans Agy99 MUL_2274 (-)

annotation: transmembrane protein
coordinates: 2542931 - 2544538
length: 535

QDRLDGVAGSRRGLRIALRGRRDPVPVAGQRSRTSSGMGDQHVRKVLDLTIRLAEVMLSSGSGTADVVAT
ANDVAQAYQITDCVVDITVTTIIVSALPTAESTPVTIVRSVRTRSTNFTRLAELDRLVQEITAGGVTVDE
AHEAMDELTQRPHPYPRWLATVCWAGFSLGIAMMLGANWRTCAIAALTAATIDRLGRVLNRIGTPYFFQR
VTGAAVATLVAVAAYLFTGEGLAALVATGIVMLLSGLTLVGAMQDAITGYMVTAVARIGEALFLTSGIVV
GILAGLQIAKTAGVEIELRVHGSGGFVVPQGPLPILLTVLGAMLAGACLTVASYAPLRSAVTAGFAAGLA
DLVLIGLGTAGFGQVIATGIAAVGVGFLATLISIRRQALALVTATAGIVPMLPGLAVFRAVFYFAADSHF
DEAQSQLLSAAATALALGSGVVLGEFVGSPLRYRAGRIGHLLRIEGPPGLRRAVGRVVRLEPTKNAQSTN
TRGQQSRSVALEPASTDHSDAAEDNDRTGGHGGHGGHGGHRDES*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. ulcerans Agy99MUL_2274--100% (535)transmembrane protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3764-0.073.64% (516) transmembrane protein
M. gilvum PYR-GCKMflv_0954-0.066.15% (517) hypothetical protein Mflv_0954
M. tuberculosis H37RvRv3737-0.073.45% (516) transmembrane protein
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_0256c-4e-0722.93% (471) hypothetical protein MAB_0256c
M. marinum MMMAR_3034-0.099.81% (535) transmembrane protein
M. avium 104-----
M. smegmatis MC2 155MSMEG_3459-0.071.20% (507) hypothetical protein MSMEG_3459
M. thermoresistible (build 8)TH_0424-0.065.56% (514) PROBABLE CONSERVED TRANSMEMBRANE PROTEIN
M. vanbaalenii PYR-1Mvan_5838-0.068.51% (524) hypothetical protein Mvan_5838

CLUSTAL 2.0.9 multiple sequence alignment


MUL_2274|M.ulcerans_Agy99           ----------------------------MQDR------------------
MMAR_3034|M.marinum_M               MGGLAPRTVVAVVFAVRGSPSKISILPGVQDR------------------
Mb3764|M.bovis_AF2122/97            ---------------------------MDQDR------------------
Rv3737|M.tuberculosis_H37Rv         ---------------------------MDQDR------------------
Mflv_0954|M.gilvum_PYR-GCK          ----------------------MLPSPMVPSRQPRTPVPFRRASVSWPPM
Mvan_5838|M.vanbaalenii_PYR-1       ---------------------------MGSDR------------------
MSMEG_3459|M.smegmatis_MC2_155      --------------------------------------------------
TH_0424|M.thermoresistible__bu      ---------------------------MTQDR------------------
MAB_0256c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

MUL_2274|M.ulcerans_Agy99           -LDGVAGSRRGLRIALRGRRD-PVPVAGQRSRTSSG-MGDQHVRKVLDLT
MMAR_3034|M.marinum_M               -LDGVAGSRRGLRIALRGRRD-PVPVAGQRSRTSSG-MGDQHVRKVLDLT
Mb3764|M.bovis_AF2122/97            -SDNTA-LRRGLRIALRGRRD-PLPVAGRRSRTSGG-IGDLHTRKVLDLT
Rv3737|M.tuberculosis_H37Rv         -SDNTA-LRRGLRIALRGRRD-PLPVAGRRSRTSGG-IDDLHTRKVLDLT
Mflv_0954|M.gilvum_PYR-GCK          EPDSTPRFRRGLRIAMRGRRD-PATGAGQRSRRPQNTSDERHTRKVLDLT
Mvan_5838|M.vanbaalenii_PYR-1       -SDGMARRRRALHFALKGRRD-PASGAGQR-RRTSGRLSERHTRKVLDLT
MSMEG_3459|M.smegmatis_MC2_155      ---------------MRGHRD-PAPVAGQRSRASAG-MGDLHTRKVLDLV
TH_0424|M.thermoresistible__bu      -STGRARLRGGLRLALRGTRD-PAPGAGQR-RAAGG-LDELHTRKVLDLT
MAB_0256c|M.abscessus_ATCC_199      -MTALPRRGRALALVRKTLKDKPVPLADAR---------HFPDAEVVTML
                                                    :  :* * . *. *         .    :*: : 

MUL_2274|M.ulcerans_Agy99           IRLAEVMLSSGSGTADVVATANDVAQAYQITDCVVDITVTTIIVSALPTA
MMAR_3034|M.marinum_M               IRLAEVMLSSGSGTADVVATANDVAQAYQITDCVVDITVTTIIVSALPTA
Mb3764|M.bovis_AF2122/97            IRLAEVMLSSGSGTADVVATAQDVAQAYQLTDCVVDITVTTIIVSALATT
Rv3737|M.tuberculosis_H37Rv         IRLAEVMLSSGSGTADVVATAQDVAQAYQLTDCVVDITVTTIIVSALATT
Mflv_0954|M.gilvum_PYR-GCK          VRLAEVMLSAGSGSADVVATAQDVAQAYRLNDCVVDVFVTTVFVSAPPTT
Mvan_5838|M.vanbaalenii_PYR-1       IRLAEVMLSSGSGTADVVATAQDVAQAYQLTDCVVDVFVTTIFVSALPTA
MSMEG_3459|M.smegmatis_MC2_155      IRLAEVMLSSGSGTADVVATAQDVAQAYRLTDCVVDITFTTIIVSAPPTA
TH_0424|M.thermoresistible__bu      IRLAEVMLSSGSGTADVVATAQDVAEAYQIKDCVVDITFTTIIVSALPNA
MAB_0256c|M.abscessus_ATCC_199      RMLGIAMLEVGQPTNLVLAKLHDIAPQYTDKELRAVVLPTVLIIQIDGVT
                                      *. .**. *. :  *:*. :*:*  *  .:  . :  *.:::.    :

MUL_2274|M.ulcerans_Agy99           ESTPVTIVRSVRTRSTNFTRLAELDRLVQEITAGGVTVDEAHEAMDELTQ
MMAR_3034|M.marinum_M               ESAPVTIVRSVRTRSTNFTRLAELDRLVQEITAGGVTVDEAHEAMDELTQ
Mb3764|M.bovis_AF2122/97            DTPPVTIMRSVRTRSTDYSRLAELDRLVQRITSGGVAVDQAHEAMDELTE
Rv3737|M.tuberculosis_H37Rv         DTPPVTIMRSVRTRSTDYSRLAELDRLVQRITSGGVAVDQAHEAMDELTE
Mflv_0954|M.gilvum_PYR-GCK          ESPAVTIVRSVRARSTDYSRLAALDELVRRITSGGVSVDQAHDAMDELSE
Mvan_5838|M.vanbaalenii_PYR-1       DSPPVTIVRAVQARSTDYTRLADLDRLVRRITSGGVSVDEAHEAMDELSE
MSMEG_3459|M.smegmatis_MC2_155      DSPPLTIMRAVRTRSTDYTRLAELDALIRDITSGGVSVDQAHAAMDVVTE
TH_0424|M.thermoresistible__bu      DHPPVTIVRSVRTRSTDFTRLAALDRLVREITSGGVSVHQAHEAMDELSE
MAB_0256c|M.abscessus_ATCC_199      G--QLEVEESTRN-TAQLDQAGHIDAIADMAVVGAIAPADAIARIYEIRC
                                        : : .:.:  :::  : . :* :    . *.::  :*   :  :  

MUL_2274|M.ulcerans_Agy99           RPHPYPRWLATVCWAGFSLGIAMMLGANWRTCAIAALTAATIDRLGRVLN
MMAR_3034|M.marinum_M               RPHPYPRWLATVCWAGFSLGIAMMLGANWRTCAIAALTAATIDRLGRVLN
Mb3764|M.bovis_AF2122/97            RPHPYPRWLATAGAAGFALGVAMLLGGTWLTCVLAAVTSGVIDRLGRLLN
Rv3737|M.tuberculosis_H37Rv         RPHPYPRWLATAGAAGFALGVAMLLGGTWLTCVLAAVTSGVIDRLGRLLN
Mflv_0954|M.gilvum_PYR-GCK          RPHPYPRWVATAGWAGFALGIAILLGGNWLVCLLAAATSAVIDQTGRRLN
Mvan_5838|M.vanbaalenii_PYR-1       QPHPYPRWIATAGWAGFALGIAMLLGGTWLTCILAAGTSVLIDRSGRLLN
MSMEG_3459|M.smegmatis_MC2_155      RPHPYPRWLSTAGWAGFALGIAMLLGGSWLTCLVAALTSAAIDRTGRVLN
TH_0424|M.thermoresistible__bu      QPHPYPRWLATAGWAGFAFGIAMLMGGTWVTCFLAAFTSAVIDRVNRLLN
MAB_0256c|M.abscessus_ATCC_199      LKPRFGTVLTVVGHTILTLGFGLALAPTSSALPAYLVLGLIVGVLMLATN
                                        :   ::..  : :::*..: :. .  .       .  :.      *

MUL_2274|M.ulcerans_Agy99           RIGTPYFFQRVTGAAVATLVAVAAYL-FTGEGLAALVATGIVMLLSGLTL
MMAR_3034|M.marinum_M               RIGTPYFFQRVTGAAVATLVAVAAYL-FTGEGLAALVATGIVMLLSGLTL
Mb3764|M.bovis_AF2122/97            RIGTPLFFQRVFGAGIATLVAVAAYL-IAGQDPTALVATGIVVLLSGMTL
Rv3737|M.tuberculosis_H37Rv         RIGTPLFFQRVFGAGIATLVAVAAYL-IAGQDPTALVATGIVVLLSGMTL
Mflv_0954|M.gilvum_PYR-GCK          RAGTPLFFQQVAGALIATLVAVAAYR-LAGLGPTALVATGIVMLLSGMTL
Mvan_5838|M.vanbaalenii_PYR-1       RVGTPMFFQQAAGASIATLVAVAAFL-FAGQGPTTLVATGIVMLLAGMTL
MSMEG_3459|M.smegmatis_MC2_155      RIGTPFFFQNVVGAAIATLVAVAAYL-VTGEGLTALVATGIVMLLSGLTL
TH_0424|M.thermoresistible__bu      RAGTPFFFQQVVGATIATVVAVAAYQ-YAGQGVTTLVATGIVVLLAGLTL
MAB_0256c|M.abscessus_ATCC_199      PMPTLAATMPAVAAFVVTVISTLIVANVPSEGLARVLAPALIAVLPGMTL
                                       *      . .* :.*:::.      .. . : ::*..:: :*.*:**

MUL_2274|M.ulcerans_Agy99           VGAMQDAITGYMVTAVARIGEALFLTSGIVVGILAGLQIAKTAGVEIELR
MMAR_3034|M.marinum_M               VGAMQDAITGYMVTAVARIGEALFLTSGIVVGILAGLQIAKTAGVEIELR
Mb3764|M.bovis_AF2122/97            VGSMQDAVTGYMLTALARLGDALFLTAGIVVGILISLRGVTNAGIQIELH
Rv3737|M.tuberculosis_H37Rv         VGSMQDAVTGYMLTALARLGDALFLTAGIVVGILISLRGVTNAGIQIELH
Mflv_0954|M.gilvum_PYR-GCK          VGSVQDALTGYMITAAARLGEVLFLTAGIVVGILAGLQVASLAGITIELQ
Mvan_5838|M.vanbaalenii_PYR-1       VGSVQDALTGYMLTAVARLGDVLFLTLGIVVGILAGLQIAALAGIQIQLR
MSMEG_3459|M.smegmatis_MC2_155      VGSVQDAITGHMITAVARLSEALFMTAGIVVGILAGLQIATVAGVTIQLN
TH_0424|M.thermoresistible__bu      VGSMQDALTGHMITALARLGDAVFLTAGIVVGILAGLQIASLAGVEIQLR
MAB_0256c|M.abscessus_ATCC_199      TIGALELTSTQLMAGSTRIVYGIAQLMLLALGVVIGVKVAGPP-------
                                    . .  :  :  :::. :*:   :     :.:*:: .:: .  .       

MUL_2274|M.ulcerans_Agy99           VHGSGGFVVPQGPLPILLTVLGAMLAGACLTVASYAPLRSAVTAGFAAGL
MMAR_3034|M.marinum_M               VHGSGGFVVPQGPLPILLTVLGAMLAGACLTVASYAPLRSAVTAGFAAGL
Mb3764|M.bovis_AF2122/97            VDATTTLATPGMPLPILVAVSGAALSGVCLTIASYAPLRSVATAGLSAGL
Rv3737|M.tuberculosis_H37Rv         VDATTTLATPGMPLPILVAVSGAALSGVCLTIASYAPLRSVATAGLSAGL
Mflv_0954|M.gilvum_PYR-GCK          VDATEIMVLPNQPASIAWAVFGATVAGACLTIASYARLRAVATAGLAAGL
Mvan_5838|M.vanbaalenii_PYR-1       VDATEYFVVPTTPRQIVVAVSGAALAGACLVIASYAKWRSVLTAGVAAGL
MSMEG_3459|M.smegmatis_MC2_155      VDATQAFVTPYRPGPIVLAVIGAAFASVCLTIASYAPWRTLLPAGLAAGF
TH_0424|M.thermoresistible__bu      VDVGQTFVVPTEPRTITVAIVGSALAGICLTIACYTPMRSAPMTGVAAAL
MAB_0256c|M.abscessus_ATCC_199      --QPSPLGPPLGSWTIALAVPVIAVG---FYLYKSAPRGSLIWLVLAIGV
                                          :  *  .  *  ::    ..   : :   :   :     .: ..

MUL_2274|M.ulcerans_Agy99           ADLVLIGLGTAGFGQVIATGIAAVGVGFLATLISIRRQAL-ALVTATAGI
MMAR_3034|M.marinum_M               ADLVLIGLGTAGFGQVIATGIAAVGVGFLATLISIRRQAL-ALVTATAGI
Mb3764|M.bovis_AF2122/97            AELVLIGLGAAGFGRVVATWTAAIGVGFLATLISIRRQAP-ALVTATAGI
Rv3737|M.tuberculosis_H37Rv         AELVLIGLGAAGFGRVVATWTAAIGVGFLATLISIRRQAP-ALVTATAGI
Mflv_0954|M.gilvum_PYR-GCK          AELVLIALWSGGLGSVIATGCAAVGVGFLATLISIRRQAP-ALVTATAGI
Mvan_5838|M.vanbaalenii_PYR-1       AEAVLIGLGRAGVGQVVATGTAAVGVGLLATLISIRRQAP-ALVTATAGI
MSMEG_3459|M.smegmatis_MC2_155      AEVVLIGLGWAGFGQVVATGVAAVGVGLFATLLSIRRQAP-ALVTSTAGI
TH_0424|M.thermoresistible__bu      ATVVIFGVGAAGLGQIMATFVAAISVGLLATLVSIRRQAP-ALVIATAGI
MAB_0256c|M.abscessus_ATCC_199      AMLGQR-LGSLFLAPAMTGFVGAVAVVPFALFAARFKGAPSAIVLLLAAF
                                    *      :    ..  ::   .*:.*  :* : :  : *  *:*   *.:

MUL_2274|M.ulcerans_Agy99           VPMLPGLAVFRAVFYFAADSHFDEAQSQLLSAAATALALGSGVVLGEFVG
MMAR_3034|M.marinum_M               VPMLPGLAVFRAVFYFAADSHFDEAQSQLLSAAATALALGSGVVLGEFVG
Mb3764|M.bovis_AF2122/97            MPMLPGLAVFRAVFAFAVNDTPDGGLTQLLEAAATALALGSGVVLGEFLA
Rv3737|M.tuberculosis_H37Rv         MPMLPGLAVFRAVFAFAVNDTPDGGLTQLLEAAATALALGSGVVLGEFLA
Mflv_0954|M.gilvum_PYR-GCK          TPMLPGMAVFRAVFYFAVEKDFAAGMTQAMVAAATALAIGAGVVMGELLG
Mvan_5838|M.vanbaalenii_PYR-1       TPMLPGMAVFRAVFYFAVERDFAAGMAQALAAAATALAIGAGVVMGELAG
MSMEG_3459|M.smegmatis_MC2_155      TPMLPGMAVFRAVYFFAVEDRFGDGLAQLLAAGATALALGAGVVLGEFIG
TH_0424|M.thermoresistible__bu      TPLLPGLAVFRAVFAFAVEGRFNDGLAQLMTASAIALGIGSGVVLGELVG
MAB_0256c|M.abscessus_ATCC_199      WCLVPGALSFVNVSEVAATGHAN--LTALLDTCMAIFSIALGLLVGASLH
                                      ::**   *  *  .*.        :  : :    :.:. *:::*    

MUL_2274|M.ulcerans_Agy99           SPLRYRAGRIGHLLRIEGPPGLRRAVGRVVRLEPTKNAQ-STNTRGQQSR
MMAR_3034|M.marinum_M               SPLRYRAGRIGHLLRIEGPPGLRRAVGRVVRLEPTKNAQ-STNTRGQQSR
Mb3764|M.bovis_AF2122/97            SPLRYGAGRIGDLFRIEGPPGLRRAVGRVVRLQPAKSQQ-PTGTGGQRWR
Rv3737|M.tuberculosis_H37Rv         SPLRYGAGRIGDLFRIEGPPGLRRAVGRVVRLQPAKSQQ-PTGTGGQRWR
Mflv_0954|M.gilvum_PYR-GCK          SPLRYRAGRIGQFLQVQGPPGLRRAVGRVVRLGPAEDQDATPASPYQRSW
Mvan_5838|M.vanbaalenii_PYR-1       SPLRYRAGRISDFLRVEGPPGLRRAVGNVVALRPAADQQSS-RSPHQRSW
MSMEG_3459|M.smegmatis_MC2_155      SPLRYRAGRVGDFFRIEGPPGLRRAVGRVVRLRPAEDAP-ITGPLRRPIE
TH_0424|M.thermoresistible__bu      SPLRYGAGRVGAFFRKDGPPGLRRGVGRVVRLRPSPAAPPQAGKLEPRLR
MAB_0256c|M.abscessus_ATCC_199      RGMRYALTVSR---------------------------------------
                                      :**                                             

MUL_2274|M.ulcerans_Agy99           SVALEPA------------STDHSDAAEDNDRTG--------------GH
MMAR_3034|M.marinum_M               SVALEPA------------STDHSDAAEDNDRTG--------------GH
Mb3764|M.bovis_AF2122/97            SVALEPT------------TADDVDAGYRGDWPA--------------TC
Rv3737|M.tuberculosis_H37Rv         SVALEPT------------TADDVDAGYRGDWPA--------------TC
Mflv_0954|M.gilvum_PYR-GCK          SVALEPL------------PAEPALEGSHTDTPG--------------TE
Mvan_5838|M.vanbaalenii_PYR-1       SVALEPE------------LSEVATEANGEDPAP--------------ER
MSMEG_3459|M.smegmatis_MC2_155      SVALEPE------------PTPSTTGDESEDTPR---------------Q
TH_0424|M.thermoresistible__bu      SLPLEPESEIEAEDAQADRPAAEAEPDDRPDSERPQPQDRLEDRADPGAD
MAB_0256c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

MUL_2274|M.ulcerans_Agy99           GGHGGHGGHRDES---
MMAR_3034|M.marinum_M               GGHGGHGGHRDES---
Mb3764|M.bovis_AF2122/97            TSATEVR---------
Rv3737|M.tuberculosis_H37Rv         TSATEVR---------
Mflv_0954|M.gilvum_PYR-GCK          DAPDAT----------
Mvan_5838|M.vanbaalenii_PYR-1       DATGER----------
MSMEG_3459|M.smegmatis_MC2_155      DGGG------------
TH_0424|M.thermoresistible__bu      DGAGQEPGKNGEPPDR
MAB_0256c|M.abscessus_ATCC_199      ----------------