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M. thermoresistible (build 8) TH_0424 ()

annotation: PROBABLE CONSERVED TRANSMEMBRANE PROTEIN
coordinates: 929501 - 931198
length: 566

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0424-100% (566)PROBABLE CONSERVED TRANSMEMBRANE PROTEIN
M. thermoresistible (build 8)TH_0574-6e-1021.19% (335) conserved hypothetical protein
M. thermoresistible (build 8)TH_3996-1e-0625.99% (227) PUTATIVE -

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3764-0.068.86% (517) transmembrane protein
M. gilvum PYR-GCKMflv_0954-0.064.95% (525) hypothetical protein Mflv_0954
M. tuberculosis H37RvRv3737-0.069.05% (517) transmembrane protein
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4839c-6e-0524.49% (294) MFS family transporter
M. marinum MMMAR_3034-0.065.56% (514) transmembrane protein
M. avium 104-----
M. smegmatis MC2 155MSMEG_3459-0.070.90% (488) hypothetical protein MSMEG_3459
M. ulcerans Agy99MUL_2274-0.065.56% (514) transmembrane protein
M. vanbaalenii PYR-1Mvan_5838-0.069.83% (527) hypothetical protein Mvan_5838

CLUSTAL 2.0.9 multiple sequence alignment


Mb3764|M.bovis_AF2122/97            ---------------------------MDQDRSDNTA-LRRGLRIALRGR
Rv3737|M.tuberculosis_H37Rv         ---------------------------MDQDRSDNTA-LRRGLRIALRGR
MMAR_3034|M.marinum_M               MGGLAPRTVVAVVFAVRGSPSKISILPGVQDRLDGVAGSRRGLRIALRGR
MUL_2274|M.ulcerans_Agy99           ----------------------------MQDRLDGVAGSRRGLRIALRGR
Mflv_0954|M.gilvum_PYR-GCK          ---MLPSPMVPSRQPRTPVPFRRASVSWPPMEPDSTPRFRRGLRIAMRGR
Mvan_5838|M.vanbaalenii_PYR-1       --------MGSDR-------------------SDGMARRRRALHFALKGR
MSMEG_3459|M.smegmatis_MC2_155      ----------------------------------------------MRGH
TH_0424|M.thermoresistible__bu      ---------------------------MTQDRSTGRARLRGGLRLALRGT
MAB_4839c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

Mb3764|M.bovis_AF2122/97            RDPLPVAGRRSRTSGG-IGDLHTRKVLDLTIRLAEVMLSSGSGTADVVAT
Rv3737|M.tuberculosis_H37Rv         RDPLPVAGRRSRTSGG-IDDLHTRKVLDLTIRLAEVMLSSGSGTADVVAT
MMAR_3034|M.marinum_M               RDPVPVAGQRSRTSSG-MGDQHVRKVLDLTIRLAEVMLSSGSGTADVVAT
MUL_2274|M.ulcerans_Agy99           RDPVPVAGQRSRTSSG-MGDQHVRKVLDLTIRLAEVMLSSGSGTADVVAT
Mflv_0954|M.gilvum_PYR-GCK          RDPATGAGQRSRRPQNTSDERHTRKVLDLTVRLAEVMLSAGSGSADVVAT
Mvan_5838|M.vanbaalenii_PYR-1       RDPASGAGQR-RRTSGRLSERHTRKVLDLTIRLAEVMLSSGSGTADVVAT
MSMEG_3459|M.smegmatis_MC2_155      RDPAPVAGQRSRASAG-MGDLHTRKVLDLVIRLAEVMLSSGSGTADVVAT
TH_0424|M.thermoresistible__bu      RDPAPGAGQR-RAAGG-LDELHTRKVLDLTIRLAEVMLSSGSGTADVVAT
MAB_4839c|M.abscessus_ATCC_199      ---------------------------------------MSTAAVHAQPH
                                                                            .:.:... . 

Mb3764|M.bovis_AF2122/97            AQDVAQAYQLTDCVVDITVTTIIVSALATTDTPPVTIMRSVRTRSTDYSR
Rv3737|M.tuberculosis_H37Rv         AQDVAQAYQLTDCVVDITVTTIIVSALATTDTPPVTIMRSVRTRSTDYSR
MMAR_3034|M.marinum_M               ANDVAQAYQITDCVVDITVTTIIVSALPTAESAPVTIVRSVRTRSTNFTR
MUL_2274|M.ulcerans_Agy99           ANDVAQAYQITDCVVDITVTTIIVSALPTAESTPVTIVRSVRTRSTNFTR
Mflv_0954|M.gilvum_PYR-GCK          AQDVAQAYRLNDCVVDVFVTTVFVSAPPTTESPAVTIVRSVRARSTDYSR
Mvan_5838|M.vanbaalenii_PYR-1       AQDVAQAYQLTDCVVDVFVTTIFVSALPTADSPPVTIVRAVQARSTDYTR
MSMEG_3459|M.smegmatis_MC2_155      AQDVAQAYRLTDCVVDITFTTIIVSAPPTADSPPLTIMRAVRTRSTDYTR
TH_0424|M.thermoresistible__bu      AQDVAEAYQIKDCVVDITFTTIIVSALPNADHPPVTIVRSVRTRSTDFTR
MAB_4839c|M.abscessus_ATCC_199      SITGLRGVLITLCLTEITSWGVLYYAFP--------VLAPRITADTGWSA
                                    :    ..  :. *:.::    ::  * .        :: .  : .*.:: 

Mb3764|M.bovis_AF2122/97            LAELDRLVQRITSGGVAVDQAHEAMDELTERPHPYPRWLATAGAAGFALG
Rv3737|M.tuberculosis_H37Rv         LAELDRLVQRITSGGVAVDQAHEAMDELTERPHPYPRWLATAGAAGFALG
MMAR_3034|M.marinum_M               LAELDRLVQEITAGGVTVDEAHEAMDELTQRPHPYPRWLATVCWAGFSLG
MUL_2274|M.ulcerans_Agy99           LAELDRLVQEITAGGVTVDEAHEAMDELTQRPHPYPRWLATVCWAGFSLG
Mflv_0954|M.gilvum_PYR-GCK          LAALDELVRRITSGGVSVDQAHDAMDELSERPHPYPRWVATAGWAGFALG
Mvan_5838|M.vanbaalenii_PYR-1       LADLDRLVRRITSGGVSVDEAHEAMDELSEQPHPYPRWIATAGWAGFALG
MSMEG_3459|M.smegmatis_MC2_155      LAELDALIRDITSGGVSVDQAHAAMDVVTERPHPYPRWLSTAGWAGFALG
TH_0424|M.thermoresistible__bu      LAALDRLVREITSGGVSVHQAHEAMDELSEQPHPYPRWLATAGWAGFAFG
MAB_4839c|M.abscessus_ATCC_199      PAVTAAFSAALVVAAAAGIGVGRWLDRHG------PRWLMTAGSLWGPAA
                                     *    :   :. ...:   .   :*         ***: *.     . .

Mb3764|M.bovis_AF2122/97            VAMLLGGTWLTCVLAAVTSGVIDRLGRLLNRIGTPLFFQRVFGAGIATLV
Rv3737|M.tuberculosis_H37Rv         VAMLLGGTWLTCVLAAVTSGVIDRLGRLLNRIGTPLFFQRVFGAGIATLV
MMAR_3034|M.marinum_M               IAMMLGANWRTCAIAALTAATIDRLGRVLNRIGTPYFFQRVTGAAVATLV
MUL_2274|M.ulcerans_Agy99           IAMMLGANWRTCAIAALTAATIDRLGRVLNRIGTPYFFQRVTGAAVATLV
Mflv_0954|M.gilvum_PYR-GCK          IAILLGGNWLVCLLAAATSAVIDQTGRRLNRAGTPLFFQQVAGALIATLV
Mvan_5838|M.vanbaalenii_PYR-1       IAMLLGGTWLTCILAAGTSVLIDRSGRLLNRVGTPMFFQQAAGASIATLV
MSMEG_3459|M.smegmatis_MC2_155      IAMLLGGSWLTCLVAALTSAAIDRTGRVLNRIGTPFFFQNVVGAAIATLV
TH_0424|M.thermoresistible__bu      IAMLMGGTWVTCFLAAFTSAVIDRVNRLLNRAGTPFFFQQVVGATIATVV
MAB_4839c|M.abscessus_ATCC_199      LIGVAMAPNYGWFLAAWLMAGIAMAAVFYP----------------PAFA
                                    :  :  .      :**     *                        .:..

Mb3764|M.bovis_AF2122/97            AVAAYLIAGQDPTALVATGIVVLLSGMTLVGSMQDAVTGYMLTALARLGD
Rv3737|M.tuberculosis_H37Rv         AVAAYLIAGQDPTALVATGIVVLLSGMTLVGSMQDAVTGYMLTALARLGD
MMAR_3034|M.marinum_M               AVAAYLFTGEGLAALVATGIVMLLSGLTLVGAMQDAITGYMVTAVARIGE
MUL_2274|M.ulcerans_Agy99           AVAAYLFTGEGLAALVATGIVMLLSGLTLVGAMQDAITGYMVTAVARIGE
Mflv_0954|M.gilvum_PYR-GCK          AVAAYRLAGLGPTALVATGIVMLLSGMTLVGSVQDALTGYMITAAARLGE
Mvan_5838|M.vanbaalenii_PYR-1       AVAAFLFAGQGPTTLVATGIVMLLAGMTLVGSVQDALTGYMLTAVARLGD
MSMEG_3459|M.smegmatis_MC2_155      AVAAYLVTGEGLTALVATGIVMLLSGLTLVGSVQDAITGHMITAVARLSE
TH_0424|M.thermoresistible__bu      AVAAYQYAGQGVTTLVATGIVVLLAGLTLVGSMQDALTGHMITALARLGD
MAB_4839c|M.abscessus_ATCC_199      ALTRWYGPGAVRALMVLTLVAGLAS--TVFVPLTAVLASHMDWRTTYLAL
                                    *:: :  .*   : :* * :. * :  *:. .:  .::.:*    : :. 

Mb3764|M.bovis_AF2122/97            ALFLTAGIVVGILISLRGVTNAGIQIELHVDATTTLATPGMPLPILVAVS
Rv3737|M.tuberculosis_H37Rv         ALFLTAGIVVGILISLRGVTNAGIQIELHVDATTTLATPGMPLPILVAVS
MMAR_3034|M.marinum_M               ALFLTSGIVVGILAGLQIAKTAGVEIELRVHGSGGFVVPQGPLPILLTVL
MUL_2274|M.ulcerans_Agy99           ALFLTSGIVVGILAGLQIAKTAGVEIELRVHGSGGFVVPQGPLPILLTVL
Mflv_0954|M.gilvum_PYR-GCK          VLFLTAGIVVGILAGLQVASLAGITIELQVDATEIMVLPNQPASIAWAVF
Mvan_5838|M.vanbaalenii_PYR-1       VLFLTLGIVVGILAGLQIAALAGIQIQLRVDATEYFVVPTTPRQIVVAVS
MSMEG_3459|M.smegmatis_MC2_155      ALFMTAGIVVGILAGLQIATVAGVTIQLNVDATQAFVTPYRPGPIVLAVI
TH_0424|M.thermoresistible__bu      AVFLTAGIVVGILAGLQIASLAGVEIQLRVDVGQTFVVPTEPRTITVAIV
MAB_4839c|M.abscessus_ATCC_199      AVLLTIITVPAHIIGLRRPWPSLPATHLAESPTR--IARSRPFISLIIAF
                                    .:::*   * . : .*:    :    .*             *        

Mb3764|M.bovis_AF2122/97            GAALSGVCLTIASYAPLRSVATAGLSAGLAELVLIGLGAAGFGRVVATWT
Rv3737|M.tuberculosis_H37Rv         GAALSGVCLTIASYAPLRSVATAGLSAGLAELVLIGLGAAGFGRVVATWT
MMAR_3034|M.marinum_M               GAMLAGACLTVASYAPLRSAVTAGFAAGLADLVLIGLGTAGFGQVIATGI
MUL_2274|M.ulcerans_Agy99           GAMLAGACLTVASYAPLRSAVTAGFAAGLADLVLIGLGTAGFGQVIATGI
Mflv_0954|M.gilvum_PYR-GCK          GATVAGACLTIASYARLRAVATAGLAAGLAELVLIALWSGGLGSVIATGC
Mvan_5838|M.vanbaalenii_PYR-1       GAALAGACLVIASYAKWRSVLTAGVAAGLAEAVLIGLGRAGVGQVVATGT
MSMEG_3459|M.smegmatis_MC2_155      GAAFASVCLTIASYAPWRTLLPAGLAAGFAEVVLIGLGWAGFGQVVATGV
TH_0424|M.thermoresistible__bu      GSALAGICLTIACYTPMRSAPMTGVAAALATVVIFGVGAAGLGQIMATFV
MAB_4839c|M.abscessus_ATCC_199      ALASCASYAVIVNLVPLMNQR--GLDG---TVAATALALGGVGQVIG---
                                    .   ..   .:.  .        *. .     .  .:  .*.* ::.   

Mb3764|M.bovis_AF2122/97            AAIGVGFLATLISIRRQAPALVTATAGIMPMLPGLAVFRAVFAFAVNDTP
Rv3737|M.tuberculosis_H37Rv         AAIGVGFLATLISIRRQAPALVTATAGIMPMLPGLAVFRAVFAFAVNDTP
MMAR_3034|M.marinum_M               AAVGVGFLATLISIRRQALALVTATAGIVPMLPGLAVFRAVFYFAADSHF
MUL_2274|M.ulcerans_Agy99           AAVGVGFLATLISIRRQALALVTATAGIVPMLPGLAVFRAVFYFAADSHF
Mflv_0954|M.gilvum_PYR-GCK          AAVGVGFLATLISIRRQAPALVTATAGITPMLPGMAVFRAVFYFAVEKDF
Mvan_5838|M.vanbaalenii_PYR-1       AAVGVGLLATLISIRRQAPALVTATAGITPMLPGMAVFRAVFYFAVERDF
MSMEG_3459|M.smegmatis_MC2_155      AAVGVGLFATLLSIRRQAPALVTSTAGITPMLPGMAVFRAVYFFAVEDRF
TH_0424|M.thermoresistible__bu      AAISVGLLATLVSIRRQAPALVIATAGITPLLPGLAVFRAVFAFAVEGRF
MAB_4839c|M.abscessus_ATCC_199      -RFGYPALAQCISVVPRTLLIMGVVAATTALLGVFASAVSLIAVAVAAGM
                                      ..   :*  :*:  ::  ::  .*.  .:*  :*   ::  .*.    

Mb3764|M.bovis_AF2122/97            DGGLTQLLEAAATALALGSGVVLGEFLASPLRYGAGRIGDLFRIEGPPGL
Rv3737|M.tuberculosis_H37Rv         DGGLTQLLEAAATALALGSGVVLGEFLASPLRYGAGRIGDLFRIEGPPGL
MMAR_3034|M.marinum_M               DEAQSQLLSAAATALALGSGVVLGEFVGSPLRYRAGRIGHLLRIEGPPGL
MUL_2274|M.ulcerans_Agy99           DEAQSQLLSAAATALALGSGVVLGEFVGSPLRYRAGRIGHLLRIEGPPGL
Mflv_0954|M.gilvum_PYR-GCK          AAGMTQAMVAAATALAIGAGVVMGELLGSPLRYRAGRIGQFLQVQGPPGL
Mvan_5838|M.vanbaalenii_PYR-1       AAGMAQALAAAATALAIGAGVVMGELAGSPLRYRAGRISDFLRVEGPPGL
MSMEG_3459|M.smegmatis_MC2_155      GDGLAQLLAAGATALALGAGVVLGEFIGSPLRYRAGRVGDFFRIEGPPGL
TH_0424|M.thermoresistible__bu      NDGLAQLMTASAIALGIGSGVVLGELVGSPLRYGAGRVGAFFRKDGPPGL
MAB_4839c|M.abscessus_ATCC_199      ARGIMTLLQATAITERWGS-THYGHLSG------LLTAPIMLTTALAPFT
                                      .    : * * :   *: .  *.: .            ::    .*  

Mb3764|M.bovis_AF2122/97            RRAVGRVVRLQPAKSQQPT-GTGGQRWRSVALEPTT---------ADDVD
Rv3737|M.tuberculosis_H37Rv         RRAVGRVVRLQPAKSQQPT-GTGGQRWRSVALEPTT---------ADDVD
MMAR_3034|M.marinum_M               RRAVGRVVRLEPTKNAQST-NTRGQQSRSVALEPAS---------TDHSD
MUL_2274|M.ulcerans_Agy99           RRAVGRVVRLEPTKNAQST-NTRGQQSRSVALEPAS---------TDHSD
Mflv_0954|M.gilvum_PYR-GCK          RRAVGRVVRLGPAEDQDATPASPYQRSWSVALEPLP---------AEPAL
Mvan_5838|M.vanbaalenii_PYR-1       RRAVGNVVALRPAADQQSS-RSPHQRSWSVALEPEL---------SEVAT
MSMEG_3459|M.smegmatis_MC2_155      RRAVGRVVRLRPAEDAPIT-GPLRRPIESVALEPEP---------TPSTT
TH_0424|M.thermoresistible__bu      RRGVGRVVRLRPSPAAPPQAGKLEPRLRSLPLEPESEIEAEDAQADRPAA
MAB_4839c|M.abscessus_ATCC_199      GAALAQLLHGYPAMFVALGVAGIIGAAAATATNPSQ--------------
                                      .:..::   *:               : . :*                

Mb3764|M.bovis_AF2122/97            AGYRGDWP-----------------ATCTSATEVR---------
Rv3737|M.tuberculosis_H37Rv         AGYRGDWP-----------------ATCTSATEVR---------
MMAR_3034|M.marinum_M               AAEDNDRT-----------------GGHGGHGGHGGHRDES---
MUL_2274|M.ulcerans_Agy99           AAEDNDRT-----------------GGHGGHGGHGGHRDES---
Mflv_0954|M.gilvum_PYR-GCK          EGSHTDTP-----------------GTEDAPDAT----------
Mvan_5838|M.vanbaalenii_PYR-1       EANGEDPA-----------------PERDATGER----------
MSMEG_3459|M.smegmatis_MC2_155      GDESEDTP-----------------RQDGGG-------------
TH_0424|M.thermoresistible__bu      EAEPDDRPDSERPQPQDRLEDRADPGADDGAGQEPGKNGEPPDR
MAB_4839c|M.abscessus_ATCC_199      --------------------------------------------