For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MTEPHTAVITRLSADFAAISRQLARVSTDLVELDRILADRPQSAPAPWPQPVSVPSPVPVPSPVPVAQPV PVPSPAPVPQPVAPYRPAYPAYPAYPPASARVRKERSDGWIGKLLAVAGVAVTLIGVVLLLVLAAQAGIL RPEFRVAAGAVLAGALVAAGWWLNGRPGGRVGAIALVATGVAAAYMDVIAVTTIYEWTSAPAGLVFASLI AGGGLTLARRWDSEHLGLLVLVPLIGLAPIVTDGISLLLVGFMLALAAVSLPVQLGKDWIWLHAARIAAA ALPVLTALLARHFESARQDLWLAGASGIAAAVALVAALILLPGTKNRAAMALLTAAGVLPVLCVSLAVDR VVAALMAATLAAALLAIVLFGERLPGVAGVVRQVFSATSAVAALIAVTVAFDGMIAGPVLLAMAVVVALV GRRDEVARWAAIGFAVVGAGVHLSYSPPSMLLEATRISAAAGISTLVSAVLLAAAAVAVVWAWDHTGGAT GLAIWIVPAAVVVYAVTSFTVTAGMLIGGGDGGFYAGHMAATICWIAMAAALFGYAARLPREDRSMLIGG GLGLVAAAMAKLFLFDLGTLDGIFRVAVFIVVGLILLGMGAGYARLLEKQDKKL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2837 | - | - | 100% (614) | hypothetical protein Mvan_2837 |
| M. vanbaalenii PYR-1 | Mvan_0626 | - | 1e-07 | 39.06% (64) | hypothetical protein Mvan_0626 |
| M. vanbaalenii PYR-1 | Mvan_5325 | - | 2e-07 | 26.43% (280) | ABC-3 protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1031c | - | 9e-08 | 27.81% (338) | hypothetical protein Mb1031c |
| M. gilvum PYR-GCK | Mflv_3578 | - | 0.0 | 74.35% (616) | hypothetical protein Mflv_3578 |
| M. tuberculosis H37Rv | Rv1004c | - | 9e-08 | 27.81% (338) | hypothetical protein Rv1004c |
| M. leprae Br4923 | MLBr_02582 | - | 1e-05 | 27.86% (323) | hypothetical protein MLBr_02582 |
| M. abscessus ATCC 19977 | MAB_4509c | - | 9e-78 | 38.29% (551) | hypothetical protein MAB_4509c |
| M. marinum M | MMAR_3960 | - | 0.0 | 57.69% (631) | hypothetical protein MMAR_3960 |
| M. avium 104 | MAV_4116 | - | 2e-09 | 27.32% (366) | hypothetical protein MAV_4116 |
| M. smegmatis MC2 155 | MSMEG_3241 | - | 1e-178 | 56.26% (615) | hypothetical protein MSMEG_3241 |
| M. thermoresistible (build 8) | TH_4594 | - | 1e-128 | 61.77% (395) | PUTATIVE putative conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_4491 | - | 4e-08 | 47.73% (44) | PPE family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1031c|M.bovis_AF2122/97 --------------------------------------------------
Rv1004c|M.tuberculosis_H37Rv --------------------------------------------------
Mvan_2837|M.vanbaalenii_PYR-1 ---MTEPHTAVITRLSADFAAISRQLARVSTDLVELDRILAD-----RPQ
Mflv_3578|M.gilvum_PYR-GCK MADMTEPHSAVIARLSADFAAISHQLTRVSGDLAALDRILTD-----RAP
TH_4594|M.thermoresistible__bu --------------------------------------------------
MMAR_3960|M.marinum_M ---MTESQHAVISRLSAEFDSLARQMARVSGELSQLDRLISDSVGAPQPA
MSMEG_3241|M.smegmatis_MC2_155 ---MTEPQRAVIARVTADLTAVSAYLNRMAGDLATLDRLVAQQSAAPRPE
MAB_4509c|M.abscessus_ATCC_199 ----MFTSHRTASTLRGMSDPQLQQMTATLDELDGRERALRAEVDALRGR
MLBr_02582|M.leprae_Br4923 ---MSRELYHRSMSWSRPSYALGMALLVVGPLMRPGYLLLRDAVSTPRSY
MAV_4116|M.avium_104 --------------------------------------------------
MUL_4491|M.ulcerans_Agy99 --------------------------------------------------
Mb1031c|M.bovis_AF2122/97 --------------------------------------------------
Rv1004c|M.tuberculosis_H37Rv --------------------------------------------------
Mvan_2837|M.vanbaalenii_PYR-1 SAPAPWPQPVSVP-------SPVPVPSPVPVAQPVPVPSPAPVPQPVAPY
Mflv_3578|M.gilvum_PYR-GCK AAAAPR-------------------PAPQPAAYWPQYP-PQPAPFRPWPQ
TH_4594|M.thermoresistible__bu --------------------------------------------------
MMAR_3960|M.marinum_M AAAPPQPQPQPVAPYWYPYWQQWAPVAPAPAAAPPRQYAPPPTARPAPQG
MSMEG_3241|M.smegmatis_MC2_155 AVAPQWS--------------------PQAPQQPPRQWTPQPVAPVAPVA
MAB_4509c|M.abscessus_ATCC_199 MVEWTQAEYLKAQR------------YWDDYRRAQGVAQAVAPAPVVMPP
MLBr_02582|M.leprae_Br4923 LSDAALG-------------------LTSAPRSTPQDFAVAMASHLVDGG
MAV_4116|M.avium_104 --------------------------------------------------
MUL_4491|M.ulcerans_Agy99 --------------------------------------------------
Mb1031c|M.bovis_AF2122/97 ------------------------------MSISCRVREGFVMRLAIVGT
Rv1004c|M.tuberculosis_H37Rv ------------------------------MSISCRVREGFVMRLAIVGT
Mvan_2837|M.vanbaalenii_PYR-1 RPAYPAYPAYPPASARVRKERSD-GWIGKLLAVAGVAVTLIGVVLLLVLA
Mflv_3578|M.gilvum_PYR-GCK APAPAPTQALTPAP---RKERSE-GWIGKLLAVAGVAVTLIGVVLLLVLA
TH_4594|M.thermoresistible__bu --------------------------------------------------
MMAR_3960|M.marinum_M PPAPAPAAAPPVSAPRRPAESTESGWIGKLLAVAGVAVTLTGVALLLVLA
MSMEG_3241|M.smegmatis_MC2_155 VPARQPDTPP--------KPRSE-GWIGKVLAMAGVAVTLVGVVSLLVLA
MAB_4509c|M.abscessus_ATCC_199 ARMPVPARAPHPAPPQLEPWWMREGFASKAMALAGAVVTLAGVVMLLVLA
MLBr_02582|M.leprae_Br4923 IVVKSALVLGLWLAGWGAARLVVTALPSAGVAGQFVASTLAVWNPYVAER
MAV_4116|M.avium_104 ---------------------------------------MPKRSLLAQAR
MUL_4491|M.ulcerans_Agy99 --------------------------------------------------
Mb1031c|M.bovis_AF2122/97 AAAAAIGGTLAVAPLTLSTPERVAGGTCSAGQQCDRLAAVLMPDTATPSG
Rv1004c|M.tuberculosis_H37Rv AAAAAIGGTLAVAPLTLSTPERVAGGTCSAGQQCDRLAAVLMPDTATPSG
Mvan_2837|M.vanbaalenii_PYR-1 AQAGILRPEFRVAAGAVLAGALVAAGWWLNGRPGGRVGAIALVATGVAAA
Mflv_3578|M.gilvum_PYR-GCK AQAGILRPEFRVSAGGALAAALVGAGWWLNTRPGGRVGAIALVATGVAAA
TH_4594|M.thermoresistible__bu --------------------------------------------------
MMAR_3960|M.marinum_M AQAGLLRPEIRVAGGTALSLALVGVAVRLRGRPGGRIGAIALAATGIATA
MSMEG_3241|M.smegmatis_MC2_155 AQAGILRPEVRVAAGAALAVALVAVAMWLDRRPGGRVGAVALAATGVAAA
MAB_4509c|M.abscessus_ATCC_199 AKSGYFGPVPRMVSGAALAGGLVALGIRVYSRPGGRVGGIATAATGFAAA
MLBr_02582|M.leprae_Br4923 LLQGHWSLLVGYGCLPWVAEAMLMLRSSDNASRPGLLGFFALACWIALAG
MAV_4116|M.avium_104 PESGSGEYVLGTWRAAALSMAVIAPAAWYG------LGALLGAAVMIP--
MUL_4491|M.ulcerans_Agy99 --------------------------------------------------
Mb1031c|M.bovis_AF2122/97 -------------------------PAAAEHAVPAPFEP---VADTIAPG
Rv1004c|M.tuberculosis_H37Rv -------------------------PAAAEHAVPAPFEP---VADTIAPG
Mvan_2837|M.vanbaalenii_PYR-1 YMDVIAVTTIYEWTSAPAGLVFASLIAGGGLTLARRWDSEHLGLLVLVPL
Mflv_3578|M.gilvum_PYR-GCK YMDVIAVTTIYDWVPAPAGLVLAAVIAGAGLTLARRWDSEHLGLLVLVPL
TH_4594|M.thermoresistible__bu -------------------------------MLARRWDSEHLGLLVLVPL
MMAR_3960|M.marinum_M YLDVIAATTIYQWVPAPAGLVLAALVGGAGLALARRWDSEHLGLLVLVPL
MSMEG_3241|M.smegmatis_MC2_155 YMDVIAVTAIYEWVPAPVGLALAGVVGACGLMLARWWGSEQLGLLVFVPL
MAB_4509c|M.abscessus_ATCC_199 FFDVLALTVIYDRIPVVAGLVLGLGIAGVGLVLARHWNSQPFASGVVAAI
MLBr_02582|M.leprae_Br4923 ------------LTPTGLMLAATVALICVAVPVEGPGEPRPRWLCAAATL
MAV_4116|M.avium_104 --------------------------VIYALARLRRHAPQARSTAELIGA
MUL_4491|M.ulcerans_Agy99 --------------------------------------------------
Mb1031c|M.bovis_AF2122/97 LVPRPGVPAAAAVPRVGPPAVPGLPNIPGAAG-------PALPPPPALPN
Rv1004c|M.tuberculosis_H37Rv LVPRPGVPAAAAVPRVGPPAVPGLPNIPGAAG-------PALPPPPALPN
Mvan_2837|M.vanbaalenii_PYR-1 IGLAPIVTDGISLLLVGFMLALAAVSLPVQLGKDWIWLHAARIAAAALPV
Mflv_3578|M.gilvum_PYR-GCK IVLAPIVTDGVSLLLVGFMLALAAVSLPVQLGKDWIWLHAARIAAAVLPL
TH_4594|M.thermoresistible__bu VLLAPVITDGITVVLIGFMLALGAASLPVQLGRDWIWLHAARTASVTLPI
MMAR_3960|M.marinum_M IGLAPVLTRGADLLLVSFMLALSAAALPVQLGKDWVWLHAARVAAPTVPL
MSMEG_3241|M.smegmatis_MC2_155 IALAPVITDGVTLLLIGFMLALSAASLPVQFGRDWFWLHAARTAAVTIPL
MAB_4509c|M.abscessus_ATCC_199 TVLAPFLTDGFTVELAAFALILLIASLTAQVGRNWPVLHAFRTVGVSLTL
MLBr_02582|M.leprae_Br4923 GSALGAALPWLTASAVGTSLTAHTVANTLGVTVFAPRAEPGLGTLASLAS
MAV_4116|M.avium_104 MLGRKAGTAAGIVQLLAYLVLAAQFAATLGLQLLQLLSPGDDPAAIVSWL
MUL_4491|M.ulcerans_Agy99 ----------------------------------------MTYPMFPPEI
Mb1031c|M.bovis_AF2122/97 LAAPSVPGVG--IPGIGIPGIGIPGIGIPGVPDPITGVNTAAAVVNGVLG
Rv1004c|M.tuberculosis_H37Rv LAAPSVPGVG--IPGIGIPGIGIPGIGIPGVPDPITGVNTAAAVVNGVLG
Mvan_2837|M.vanbaalenii_PYR-1 LTALLARHFESARQDLWLAGASGIAAAVALVAALILLPGTKNRAAMALLT
Mflv_3578|M.gilvum_PYR-GCK LVALAARHID-SREDLWLAGACGIAAVIALTAALILLPGTGNRVVMALLT
TH_4594|M.thermoresistible__bu LGALLGASFAQDRVPALTA-ACGIAAVLALAAALLLAPSTRNHTALGLLT
MMAR_3960|M.marinum_M LIALVAAGKH--DNTWLLGAACGVAAILAIVSGLIVLPGGKNAAALAVLT
MSMEG_3241|M.smegmatis_MC2_155 LVALVSAAIG-GREDLRLALVCALAAVPALVGGVTVSRFSTRPVATTVVS
MAB_4509c|M.abscessus_ATCC_199 LTAIHVSYTA----SLALLAMSVMALLVTLVGSLWLLTGEHDDITSSVMI
MLBr_02582|M.leprae_Br4923 LGGIWNGEAVPTSRTTLFAVLSATVLLGVVVAGLPVAVRRPAVVPLLVLA
MAV_4116|M.avium_104 PVGAAAAALVVGATACWASTRAVASLAMPLVLAGLLLYVCLAVAVTALVT
MUL_4491|M.ulcerans_Agy99 NSALIEAGPG------SAPMLGAAAAWCGLASELRAAAESFASITSDLAS
. . :
Mb1031c|M.bovis_AF2122/97 VGGTAAGVVTASAVAVTYLVLAVNALESSGILPTARG------TASTVAS
Rv1004c|M.tuberculosis_H37Rv VGGTAAGVVTASAVAVTYLVLAVNALESSGILPTARG------TASTVAS
Mvan_2837|M.vanbaalenii_PYR-1 AAGVLPVLCVSLAVDRVVAALMAATLAAALLAIVLFG--ERLPGV-AGVV
Mflv_3578|M.gilvum_PYR-GCK VAGIVPVLCVNLAVDRVVAALMAAALAAALLAVALLA--DRLPGV-DGVV
TH_4594|M.thermoresistible__bu AAGTLPVLCVSWAERPAVSALMAAALSAALLAMAAGAGLIRVELVRTGPL
MMAR_3960|M.marinum_M VVGTLPVLAAAVAVDRVFAALLAGTLAAALLAIVLVG--SELPTI----F
MSMEG_3241|M.smegmatis_MC2_155 ALGTVPLLCVSATADRVPAVLLIAGLAAAALAVAAIG--DRLPGI-GAPV
MAB_4509c|M.abscessus_ATCC_199 AVASSPVLYGALFFPVWPLGVLVPVGVAVVMGAVLLL-----VGALPVHA
MLBr_02582|M.leprae_Br4923 AVAVATPAALATGPGIDMLKAVVNAVPGLGVLRDGQK------WVALAVP
MAV_4116|M.avium_104 LSTDPVVIGSAATPRPLSGQLVGFGLGMVGVELLTVR----TPRIARPGR
MUL_4491|M.ulcerans_Agy99 GAWQGPAATAMTQAAAPYAAWLCTAAAQ----------------------
Mb1031c|M.bovis_AF2122/97 LLLPGAQSAAAALPAVGLPALPGVTPASLLAMAAAAGLPG------VGFP
Rv1004c|M.tuberculosis_H37Rv LLLPGAQSAAAALPAVGLPALPGVTPASLLAMAAAAGLPG------VGFP
Mvan_2837|M.vanbaalenii_PYR-1 RQVFSATSAVAALIAVTVAFDGMIAGPVLLAMAVVVALVG--RRDEVARW
Mflv_3578|M.gilvum_PYR-GCK RRVFAVTSAIAALIAVTTAFDGRVGGPVLLAMAVVVAIAV--GRDVVGRW
TH_4594|M.thermoresistible__bu RRILSVWAAVAALIAVTVAFDAPVAAPVLLAMATVVAVAG--RHDRTARW
MMAR_3960|M.marinum_M TRVLAAWSAISALVAVTVAFDGHVEGPILLALAIVVAIAG--RHDRMALW
MSMEG_3241|M.smegmatis_MC2_155 RRVWAATSAAAALIAVLVAFDGTVAAPVLLAMSIAIAVGG--QRDPVGRC
MAB_4509c|M.abscessus_ATCC_199 RITVAAVAGVALLQASVDGARDALLAVVLLAIALSCCAIGYQLRDRVALV
MLBr_02582|M.leprae_Br4923 GYSLAGAGAVVTLGRWLRPSRPLSPVVTALACCLALILALP----DLAWG
MAV_4116|M.avium_104 SMSLATAVVAAAAVVLWVGDHRGVAGPWRWSATMLAEAVP-------EFY
MUL_4491|M.ulcerans_Agy99 --SESAASQAGAVATAFEAARTAIVSPVIINANRALTALL----------
.
Mb1031c|M.bovis_AF2122/97 SLPGVSPTDLMAMAAAAGLPTSLPGLAGMSPAELTALVAGGLPMLAAAGL
Rv1004c|M.tuberculosis_H37Rv SLPGVSPTDLMAMAAAAGLPTSLPGLAGMSPAELTALVAGGLPMLAAAGL
Mvan_2837|M.vanbaalenii_PYR-1 AAIGFAVVGAGVHLSYSPPSMLLEATRISAAAGISTLVSAVLLAAAAVAV
Mflv_3578|M.gilvum_PYR-GCK VAIGFAVIGAAAHLSYAPLAVLLQPVEVSTATGISTLVSSLLLATAAVTI
TH_4594|M.thermoresistible__bu IALGFAVVGGLYYLGVAPPYRVLRPIAVAAPTAVAVLIASVLLICCVVAI
MMAR_3960|M.marinum_M AAAGFGIVGLGLYYSYAPLHALLTATVMPTSIAVSTLAASLLSIAFVVAM
MSMEG_3241|M.smegmatis_MC2_155 AAIGFALIGAMFYLDHAAPAMLVEATPLDGPTVASVVIGSVMLIGAAAAN
MAB_4509c|M.abscessus_ATCC_199 LGQVFGGLGAAVYLAYVRPELLTDSASAVLYAGPLLVIASVLMAATVGMV
MLBr_02582|M.leprae_Br4923 VWGKVQPVHYPSGWAAVAATINDRGEGPGWVAVLPAGTMRRFSWSGTAPV
MAV_4116|M.avium_104 TDEGRRWMAAAGIALAVAAALVTGWAATRAAAGLAAMRGATPNAGLRLTV
MUL_4491|M.ulcerans_Agy99 ANTNFFGLNFPAIAAAEGLYEEMWAQDVAVMSGYHATVSEIWSQLSQWPP
Mb1031c|M.bovis_AF2122/97 PAGLAGVDP--------------------ATLAAALPALAAGGLPPGLPA
Rv1004c|M.tuberculosis_H37Rv PAGLAGVDP--------------------ATLAAALPALAAGGLPPGLPA
Mvan_2837|M.vanbaalenii_PYR-1 VWAWDHTGGATGLAIWIVPAA---VVVYAVTSFTVTAGMLIGGGDGGFYA
Mflv_3578|M.gilvum_PYR-GCK VWMWDRT----ETALWVGAAV---VTVYAVTSCTVTAGMLVIGGDGGFYA
TH_4594|M.thermoresistible__bu VWTWRAHVPAAGPLPWLGAAT---VLLYAVTTFTVTAGVLAGGVGGGFFA
MMAR_3960|M.marinum_M SRACAGIGGQNRDIRRILAAVGGVLVIYAVTAFTVTAGVLIAGTEAGFLA
MSMEG_3241|M.smegmatis_MC2_155 GWTWSRTVSDTEVVRLVWVAVS-AVIGYAATALTVTVGVALGGAEVGFLA
MAB_4509c|M.abscessus_ATCC_199 LATMARVGWASPQSAPTRAVLAGVSMLYSGTAAVVLSGTALLGNNDGFLL
MLBr_02582|M.leprae_Br4923 LDPLPRWVRDDVLTTGDLIISGVMVAGEGNHARAAQDLLLSGPNPSALTA
MAV_4116|M.avium_104 MG----------------------------LVAVVAVVVSAHGMRSIGMV
MUL_4491|M.ulcerans_Agy99 LQQLLR-------------------------LLPGCKAPSSSGGSPSPTP
Mb1031c|M.bovis_AF2122/97 LPGVDPAALAAALPALAAGLPALP----AGLPPLPAVPALPAPPPLPGPP
Rv1004c|M.tuberculosis_H37Rv LPGVDPAALAAALPALAAGLPALP----AGLPPLPAVPALPAPPPLPGPP
Mvan_2837|M.vanbaalenii_PYR-1 GHMAATICWIAMAAALFGYAARLP-REDRSMLIGGGLGLVAAAMAKLFLF
Mflv_3578|M.gilvum_PYR-GCK GHMVATILWIAMAAVLFWYAARLP-REDRSVPLGGGLGLVAAAMAKLFLF
TH_4594|M.thermoresistible__bu GHMAATICWIGLAAALLWYAARRP-RADRAMPLGGGLALVAAAVAKLFLF
MMAR_3960|M.marinum_M GHMAATICWIAVAAALFVYALRVADRERRTAPIGAGLALTGAATAKLFLF
MSMEG_3241|M.smegmatis_MC2_155 GHMAATLSWIVAAALAFGYAARRP-GASRSVLIGGGLVLVAAATGKLFLF
MAB_4509c|M.abscessus_ATCC_199 GHGLATVSWMAVSVALLLAGLRRY--RGRSWVTRTGFVLAAMAVAKLFLF
MLBr_02582|M.leprae_Br4923 AGVAWLVVESDTAGDMGASARTLAALQPTYRDDAIGLYRIGGSNAKTAPS
MAV_4116|M.avium_104 ILGAAPLLLMALYVLVAEANSRIPGDSVVAWWVRLVMPALAVVAVVKPLV
MUL_4491|M.ulcerans_Agy99 NPNPDPSPTPDPTPTPTPDPTPTP----TPEPTPAPAPEPAPEPTPVEPA
Mb1031c|M.bovis_AF2122/97 PLPALPSRLCTPGFGPIGVCIP----------------------------
Rv1004c|M.tuberculosis_H37Rv PLPALPSRLCTPGFGPIGVCIP----------------------------
Mvan_2837|M.vanbaalenii_PYR-1 DLGTLDGIFRVAVFIVVGLILLGMGAGYARLLEKQDKKL-----------
Mflv_3578|M.gilvum_PYR-GCK DLGTLDGIFRVVVFIVVGLTLLGIGAGYARLLERQDKQAATRTFDTT---
TH_4594|M.thermoresistible__bu DLGTLDGIFRVVVFIVVGLVLLGTGGGYARWLTHAAGESHPAGESRGTGK
MMAR_3960|M.marinum_M DLATLDGIFRVAAFIVVGLVLLAMGTGYARSLAR----------------
MSMEG_3241|M.smegmatis_MC2_155 DLGTLDGMYRVVLFIVGGLVLLGMGAGYARFLAQQSDGRSDAQPGTDHEA
MAB_4509c|M.abscessus_ATCC_199 DLATLDGVARIGAFIVTGLLLLGGGTLYAREYATRSEEPSAERPVT----
MLBr_02582|M.leprae_Br4923 PYRGLLIAAHLTWLVILVMAVVGMQITRHTHFRDVSSVALLSRR------
MAV_4116|M.avium_104 DSQFAPVQVATVVAAAIGVGAAGAAPLLARHRERTAKSE-----------
MUL_4491|M.ulcerans_Agy99 PVTVLPTM------------------------------------------
Mb1031c|M.bovis_AF2122/97 --------
Rv1004c|M.tuberculosis_H37Rv --------
Mvan_2837|M.vanbaalenii_PYR-1 --------
Mflv_3578|M.gilvum_PYR-GCK --------
TH_4594|M.thermoresistible__bu HQADNEPV
MMAR_3960|M.marinum_M --------
MSMEG_3241|M.smegmatis_MC2_155 HST-----
MAB_4509c|M.abscessus_ATCC_199 --------
MLBr_02582|M.leprae_Br4923 --------
MAV_4116|M.avium_104 --------
MUL_4491|M.ulcerans_Agy99 --------