For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VTSAGADEPVLDLRLVPPALAAWAATATGILWPTGYFTAAALGIGAIWVRLSRRRWNGAVAAAVASILIA GMGFSVAAAIRHHGVQNHPLRSRVGQIVTAQLRVTDDPRSVTGGRAMMRADLVGLGDPVQGMTGAVLVFG SSSLLGRVAVGDTVRARAAVARPGRRDLTVATLTVVAEPSIFGHSPIHGVANGIRDRFVDVSRNALPAGE AALLPGLVLGDTSALDAQTVAMFRTSGLTHLMAVSGANVSIVCGAVLLLGRLIGLRTSVVLAGLVLVGFV ILVRPSPSVLRAAVMGAIGLLGVLTARRRQAIPALAATILVLLAVSPGLAVDIGFALSVVATAALVVLAP RWSMRLTARGWPKPLADALCVAVAAQLVTAPVIAAISGSVSMASIAANVLAGLVIVPITVLGTAAAALTV VSPQVAGLLARFCGPELWWLLRVADYASAGGTTAIPVPAGVLGFAVVAVLLGIAVWLWRRRWFRGLVWTG VLCALALMISARVVS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_1627 | - | - | 100% (505) | hypothetical protein MAB_1627 |
| M. abscessus ATCC 19977 | MAB_0549c | - | 6e-05 | 26.76% (299) | putative heme/hemin ABC transporter, permease protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2437c | - | 1e-121 | 50.21% (478) | hypothetical protein Mb2437c |
| M. gilvum PYR-GCK | Mflv_2663 | - | 1e-123 | 51.57% (479) | ComEC/Rec2-related protein |
| M. tuberculosis H37Rv | Rv2414c | - | 1e-125 | 49.41% (506) | hypothetical protein Rv2414c |
| M. leprae Br4923 | MLBr_00335 | - | 1e-07 | 26.33% (281) | putative ABC-transporter transmembrane protein |
| M. marinum M | MMAR_3735 | comEC | 1e-117 | 46.94% (507) | membrane metal-binding protein ComEC |
| M. avium 104 | MAV_1768 | - | 1e-124 | 52.30% (501) | competence protein |
| M. smegmatis MC2 155 | MSMEG_4573 | - | 1e-122 | 50.50% (503) | competence protein |
| M. thermoresistible (build 8) | TH_1460 | - | 1e-110 | 52.46% (427) | competence protein |
| M. ulcerans Agy99 | MUL_3679 | comEC | 1e-112 | 45.91% (501) | membrane metal-binding protein ComEC |
| M. vanbaalenii PYR-1 | Mvan_3914 | - | 1e-124 | 53.33% (480) | ComEC/Rec2-related protein |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_4573|M.smegmatis_MC2_155 ----MTDEPELLDLRLVPAALTAWLVTAAGIVWYIAGSVLVVIVVTLLAA
TH_1460|M.thermoresistible__bu --------------------------------------------------
Mflv_2663|M.gilvum_PYR-GCK ---------MAVDLRLVPAALTSWLVTAAGILWLWAGALAVLAVAVGVTA
Mvan_3914|M.vanbaalenii_PYR-1 -----------MDLRLVPAALTSWAVTAAGIVWLRAGAVAATLTAVAAAA
Mb2437c|M.bovis_AF2122/97 -MGFG---ASRLDVRLVPAALVSWIVTAAGIVWPIGNVCALCCVVVALGG
Rv2414c|M.tuberculosis_H37Rv -MGFG---ASRLDVRLVPAALVSWIVTAAGIVWPIGNVCALCCVVVALGG
MMAR_3735|M.marinum_M MAGAGRDVAERLDVRLVPGALTSWIVTAAGIVWPVGRACASGCLLLALGA
MUL_3679|M.ulcerans_Agy99 MAGAGRDVAERLYVRLVPGALTSWIVTAAGIVWPVGRACASGCLLLALGA
MAV_1768|M.avium_104 -------------MRLVPSALTCWAVTAGGIWWPIGRELAWCCVGLLAIA
MAB_1627|M.abscessus_ATCC_1997 -MTSAGADEPVLDLRLVPPALAAWAATATGILWPTG-----YFTAAALGI
MLBr_00335|M.leprae_Br4923 --------------------------------------------------
MSMEG_4573|M.smegmatis_MC2_155 AVTRWAGPA---------RTGAVVIAVAVTGVGFAVAIGLRVNQVREHPV
TH_1460|M.thermoresistible__bu ---------------------------------MAVAITLRTDHLDRHPL
Mflv_2663|M.gilvum_PYR-GCK AVGWWAARR-TAAEAPRRGRAAATVAVALIGAGFAVAVTARVDAAGDHPI
Mvan_3914|M.vanbaalenii_PYR-1 LIGWWAARRRLRGGADRRALGSAVVAVAVVGSGFAVAVSLRVDAAAEHAI
Mb2437c|M.bovis_AF2122/97 GALWWCVARRSWHAPRLGSISAGLVAVGMVGAGYGLAVALRSEAVDRHPI
Rv2414c|M.tuberculosis_H37Rv GALWWCVARRSWHAPRLGSISAGLVAVGMVGAGYGLAVALRSEAVDRHPI
MMAR_3735|M.marinum_M GVLWWITDRRPRSRRWPRAVSAGLVTVGVVGAGFGMAIALRTEALARHPI
MUL_3679|M.ulcerans_Agy99 GVLWWITDRRPRSRRWPCAVSAGLVTVGVVGAGFGMAIALRTEALASHPI
MAV_1768|M.avium_104 GALRWRAARRHR-RPRLSSVSAGLAAIGVVGAGFGFAVALRADAVDHHPI
MAB_1627|M.abscessus_ATCC_1997 GAIWVRLSRRRWN----GAVAAAVASILIAGMGFSVAAAIRHHGVQNHPL
MLBr_00335|M.leprae_Br4923 --------------------------------------------------
MSMEG_4573|M.smegmatis_MC2_155 VDRYGGAATVRVVVSEVPRPTRG---NRLMFRAALTELDG--APVSGRVM
TH_1460|M.thermoresistible__bu TDRYGTVAGVVVTPTEIPRPLGG---GRLMFRGTLRSADG--QRMSGRVV
Mflv_2663|M.gilvum_PYR-GCK TGRVGSVVEVTVTPADTPRVLAG---GRTMIRGTLVRLDG--APSSGDVV
Mvan_3914|M.vanbaalenii_PYR-1 TGYFGSDTSVVVTPSETPRVLDG---GRTMIRGALVALAG--APSSGDVL
Mb2437c|M.bovis_AF2122/97 TVAFGTSALVTVTPSESPVSLGR---GRLMFRATVQRLRD--DETSGRVV
Rv2414c|M.tuberculosis_H37Rv TVAFGTSALVTVTPSESPVSLGR---GRLMFRATVQRLRD--DETSGRVV
MMAR_3735|M.marinum_M SAAFGTSAAVTVTPSESALSLGS---DRLMFRATIQRLRD--DEISGRVV
MUL_3679|M.ulcerans_Agy99 SAAFGTSAAVTVTPSESALSLGS---DRLMFRATIQRLRD--DEISGRVV
MAV_1768|M.avium_104 AADFGASAPVTVTPSESPVSLGSGTQGRLMFRATLQQLRS--DQMSGRVV
MAB_1627|M.abscessus_ATCC_1997 RSRVGQIVTAQLRVTDDPRSVTG---GRAMMRADLVGLGDPVQGMTGAVL
MLBr_00335|M.leprae_Br4923 --------------------------------------------------
MSMEG_4573|M.smegmatis_MC2_155 VFASG-RFG---ALTPGSPVGFRATLSRPMRADLTVAALSARGDPTIGEA
TH_1460|M.thermoresistible__bu VFASAARYG---ELIAGQPAGFTARIGRPARRDLTVATLSATGSPVPGDA
Mflv_2663|M.gilvum_PYR-GCK VFAAAGDYA---RLSAGQSAAFRARVSRPTRRDLTVAVLSAQGRPVAGDA
Mvan_3914|M.vanbaalenii_PYR-1 VFASGAGYA---NLTAGQPAAFRARVSRPKRRDLTVAVLSAHGEPVPGEA
Mb2437c|M.bovis_AF2122/97 VFARALDF---GELMVGQPVQFRARISRPARHDLTVAVFNATGRPTVGRA
Rv2414c|M.tuberculosis_H37Rv VFARALDF---GELMVGQPVQFRARISRPARHDLTVAVFNATGRPTVGRA
MMAR_3735|M.marinum_M VFARASEFEETGELMVGRPVRFTARISGPARHDLTVAVLNSAGAVKAGRA
MUL_3679|M.ulcerans_Agy99 VFARAFEFEEMGELMVGRPVRFTARISGPARHDLTVAVLNSAGAVKAGRA
MAV_1768|M.avium_104 VFARGPDF---GGLMVGQPVRFTARIGRPTRRDLTVAVLTASGRPTLGSA
MAB_1627|M.abscessus_ATCC_1997 VFGSSSLLG---RVAVGDTVRARAAVARPGRRDLTVATLTVVAEPSIFGH
MLBr_00335|M.leprae_Br4923 -----------------MDDRLAHMWNHLFSFDITTHLLSHN--------
*:*. :.
MSMEG_4573|M.smegmatis_MC2_155 PAVQRGAQRIRTSFAETARLVLPADQAAILPGLVLGDTSTVSTQTTAEFR
TH_1460|M.thermoresistible__bu PALLRAAHRVRAGFAESARAVLPAEQAAMLPALVLGDTSAVSGRVTAEFR
Mflv_2663|M.gilvum_PYR-GCK APIHRAAHGLRTEFADAARLALAADPAAMLPALVLGDTTAVPARIAGEFR
Mvan_3914|M.vanbaalenii_PYR-1 APIHRAAHRLRARFAESARLALPPDQAATLPALVLGDTSALSAQTTAEFR
Mb2437c|M.bovis_AF2122/97 GPVHRAAHIVRHRFAAAVREVLPADQATMLPALVLGDTSTVTALTSREFR
Rv2414c|M.tuberculosis_H37Rv GPVHRAAHIVRHRFAAAVREVLPADQATMLPALVLGDTSTVTALTSREFR
MMAR_3735|M.marinum_M GALQRAAHQVRGRFAAAARRVLPADQAAMLPALVLGDTSTVSTETGRAFR
MUL_3679|M.ulcerans_Agy99 GALQRAAHQVCGRFAAAARRVLPADQAAMLPALVLGDTSTVSTETGRAFR
MAV_1768|M.avium_104 SAVQRAAHEVRRRFAAAVRDTLPADQAALLPALVLGDTSAVPTPTGRDFR
MAB_1627|M.abscessus_ATCC_1997 SPIHGVANGIRDRFVDVSRNALPAGEAALLPGLVLGDTSALDAQTVAMFR
MLBr_00335|M.leprae_Br4923 -------------------FVQQALLAALLLGLVAGLIGPFIVMRQMSFA
. . *: * .** * .. *
MSMEG_4573|M.smegmatis_MC2_155 SSGLTHLTAVSGANVTIVCG-----ALLLSAAVVGPRIAVGLALVGLIAF
TH_1460|M.thermoresistible__bu AAGLTHLTAVSGANVTIVCG-----AVLLSAAVVGPRCAVAAAAVALVAF
Mflv_2663|M.gilvum_PYR-GCK ASGLAHLTAVSGANVTIVCG-----AVLLSAVLIGPRAAVGLAAITLLAF
Mvan_3914|M.vanbaalenii_PYR-1 RSGLAHLTAVSGANVTIVCG-----AVLLSAVLIGPRAAVALAALTLVGF
Mb2437c|M.bovis_AF2122/97 AAGLTHLTAVSGANVTIVCA-----AALVSARLIGPRAAVVCAAVALVAF
Rv2414c|M.tuberculosis_H37Rv AAGLTHLTAVSGANVTIVCA-----AALVSARLIGPRAAVVCAAVALVAF
MMAR_3735|M.marinum_M SAGMTHLTAVSGANVTIVCG-----AVLFSARWVGPRAAVALAGIALVAF
MUL_3679|M.ulcerans_Agy99 SAGMTHLTAVSGANVTIVCGAVRCGAVLFSARWVGPRAAVALAGIALVAF
MAV_1768|M.avium_104 AAGMTHLMAVSGANVTIVCA-----AVLFSARLIGPRAAVLLAALALVAF
MAB_1627|M.abscessus_ATCC_1997 TSGLTHLMAVSGANVSIVCG-----AVLLLGRLIGLRTSVVLAGLVLVGF
MLBr_00335|M.leprae_Br4923 VHGSSELS-LTGATFALLAG---------FEMGVGALVGSALAATLFGIL
* :.* ::**..:::.. :* . * : :
MSMEG_4573|M.smegmatis_MC2_155 VIVVQPSASVLRSAVMGAVTLLAIVTHRRRQAIPALAASVLVLMAAAPEL
TH_1460|M.thermoresistible__bu VIVVLPSASVLRAAVMAAITLLAMVSHRRRQAIPALAASVLGLVVAAPEL
Mflv_2663|M.gilvum_PYR-GCK VVVVQPSPSVLRAAVMGAITLLAVLSHRRRQALPALSATVIALMVGAPEL
Mvan_3914|M.vanbaalenii_PYR-1 VVVVQPSPSVLRAAVMGAITLLAVLSHRRRQALPALAATVIALMIGVPEL
Mb2437c|M.bovis_AF2122/97 VILVQPTASVLRAAVMGAIALVGMLSARRRQAIPALSGSVLVLLAAAPHL
Rv2414c|M.tuberculosis_H37Rv VILVQPTASVLRAAVMGAIALVGMLSARRRQAIPALSGSVLVLLAAAPHL
MMAR_3735|M.marinum_M VIVVQPTASVLRAALMASIALAAMLSSRRRQAIPALSTTVLVLLVAAPHL
MUL_3679|M.ulcerans_Agy99 VVVVQPTASVLRAALMASIALAAMLSSRRRQAIPALSTTVLVLLVAAPHL
MAV_1768|M.avium_104 VVVVQPTASVLRAAVMGAIALAGMLTSRRRQAIPALAATVLVLLAVAPQL
MAB_1627|M.abscessus_ATCC_1997 VILVRPSPSVLRAAVMGAIGLLGVLTARRRQAIPALAATILVLLAVSPGL
MLBr_00335|M.leprae_Br4923 GRRARERDSVIGVVLAFGLGLAVLFIH----LYPGRTGTSLALLTGQIID
. **: .: .: * :. *. : : : *:
MSMEG_4573|M.smegmatis_MC2_155 AVDVGFALSVCATAAIVVIAPVWARRLEARGWPSTLAAAVSVAAAAQLVT
TH_1460|M.thermoresistible__bu AVDAGFALSVAATAALIVIAPAWSRRLTARGWPKPLADAVSIATAAQVVT
Mflv_2663|M.gilvum_PYR-GCK AVDVGFALSVSATAALVVIAPAWSRRLTERGWPKPPADAVSVALAAQLVT
Mvan_3914|M.vanbaalenii_PYR-1 AVDVGFALSVAATAALVVLAPAWSRRLTGRGWPKPVADAVSVAVAAQLVT
Mb2437c|M.bovis_AF2122/97 AVDIGFALSVAATGALVVIAPVWSRRLVDRGCPKVLADALAVAAAAQLVT
Rv2414c|M.tuberculosis_H37Rv AVDIGFALSVAATGALVVIAPVWSRRLVDRGCPKVLADALAVAAAAQLVT
MMAR_3735|M.marinum_M AVDMGFALSVVATAALVVVAPGWSDGLVARGWPKVLADGLAVATAAQVVT
MUL_3679|M.ulcerans_Agy99 AVDMGFALSVVATAALVVVAPGWSDGLVVRGWPKVLADGLAVATAAQVVT
MAV_1768|M.avium_104 SVDVGFALSVLATAALVVLAPAWSRRLADRGWPKPLADAVAVAWAAQLVT
MAB_1627|M.abscessus_ATCC_1997 AVDIGFALSVVATAALVVLAPRWSMRLTARGWPKPLADALCVAVAAQLVT
MLBr_00335|M.leprae_Br4923 VGYSGLATLALVCLFVIAVLTTCYRPLLFATVDPEVAAACGVPVHALGIV
*:* . . ::.: . * * . :. * :.
MSMEG_4573|M.smegmatis_MC2_155 APLVAGISGRFSVVAVAANLAVVGVIPPITVLGTAAAALAAVWPAGAGLL
TH_1460|M.thermoresistible__bu APLIAGISGRLSLVSIAANLAVAVVIPPITVLGTVAAALGACWPDGAQLL
Mflv_2663|M.gilvum_PYR-GCK APLVAGISGSVSLVGVLANLAVAPVIPPITVFGTAAAALCALWPSGAELL
Mvan_3914|M.vanbaalenii_PYR-1 APLVAGISGSVSVVAVLANLVVAPVIPPITVIGCAAAALCPLWPAGAELL
Mb2437c|M.bovis_AF2122/97 APLVAAISGRVSLVAVVANLAVAAVIAPITVLGSVAAVLVVPWPAGAQVL
Rv2414c|M.tuberculosis_H37Rv APLVAAISGRVSLVAVVANLAVAAVIAPITVLGSVAAVLVVPWPAGAQVL
MMAR_3735|M.marinum_M APLVAAISGRFSVVAVVANLAVAAVIAPITVLGSAAAVLVIPWPAGAQLL
MUL_3679|M.ulcerans_Agy99 APLVAAISGRFSVVAVVANLAVAAVIAPITVLGSAAAVLVIPWPAGAQLL
MAV_1768|M.avium_104 APLVAAISGRFSVVAAAANLLVAAVIAPITVLGTAAAALCPIWPAGARLL
MAB_1627|M.abscessus_ATCC_1997 APVIAAISGSVSMASIAANVLAGLVIVPITVLGTAAAALTVVSPQVAGLL
MLBr_00335|M.leprae_Br4923 FAALVGLVAAQAVQVVGALLVMSLLITPAAAAAQVVASPVAAMVA-----
. :..: . :: * : :* * :. . ..*
MSMEG_4573|M.smegmatis_MC2_155 IRFTGPEVWWLLSVARWASGMPAATVPTPSGWAGVLLVAISGVTLTVLWR
TH_1460|M.thermoresistible__bu IRFAGPEVWWLLEVARWSAAVPGSAVPVPSGVAGVTVVAGGAVAAVLLWR
Mflv_2663|M.gilvum_PYR-GCK IRFTGPEVWWLLTVARWAARMPAATVPVPSGIAGVLTVAVLAVAVAAVWH
Mvan_3914|M.vanbaalenii_PYR-1 IRFTGPEVWWLLGVARWAAGLPIAAVPVPSGAAGVLTVAIAAVAVAATWH
Mb2437c|M.bovis_AF2122/97 IRFTGPEVWWVLRVAHWASGVPAATVPVAAGLPGVLLVGGATVFTVAQWR
Rv2414c|M.tuberculosis_H37Rv IRFTGPEVWWVLRVAHWASGVPAATVPVAAGLPGVLLVGGATVFTVAQWR
MMAR_3735|M.marinum_M IRFTGPQVWWVLHVARWAADVPGATVAVPAGLAGVLIVGGVTVLVVALWR
MUL_3679|M.ulcerans_Agy99 IRFTGPQVWWVLHVARWAADVPGATVAVPAGLAGVLIVGGVTVLVVALWR
MAV_1768|M.avium_104 IRFTGPELWWVGGVAHRAAGLPGATVPVPDGTAGTLIVGGVTLLAVVAWR
MAB_1627|M.abscessus_ATCC_1997 ARFCGPELWWLLRVADYASAGGTTAIPVPAGVLGFAVVAVLLGIAVWLWR
MLBr_00335|M.leprae_Br4923 -----------AVIFAEVSAVGGVVLSLAPGVPVSVFVATISFLIYLFCW
: : .:. . * *.
MSMEG_4573|M.smegmatis_MC2_155 SRWVRRAVAGA----AVVMLAWTVAGQVVGAVGPT-----
TH_1460|M.thermoresistible__bu RPWIRWATAGT----VLSLVAWTVAGP--GPSG-------
Mflv_2663|M.gilvum_PYR-GCK -----RVVSGR----RETIMR-------------------
Mvan_3914|M.vanbaalenii_PYR-1 -----WVVSHR----RDTIVR-------------------
Mb2437c|M.bovis_AF2122/97 LALVSRGHVQNDGGGRHMSACLVAVRAGRPFVTPSWGERG
Rv2414c|M.tuberculosis_H37Rv WRWFRAAMCKT---MAVAVICLLAWSLSG-LVGPS-----
MMAR_3735|M.marinum_M FRWIRLAMISA----LLATLGSGLAWSVAGLVGPS-----
MUL_3679|M.ulcerans_Agy99 FRWIRLAMISA----LLATQGS-------GVVD-------
MAV_1768|M.avium_104 WRRFRAAAAAA----LLIDLAWVLSGLT------------
MAB_1627|M.abscessus_ATCC_1997 RRWFRGLVWTG----VLCALALMISARVVS----------
MLBr_00335|M.leprae_Br4923 LLGRHREVCA------------------------------