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MDQDRSDNTALRRGLRIALRGRRDPLPVAGRRSRTSGGIDDLHTRKVLDLTIRLAEVMLSSGSGTADVVA TAQDVAQAYQLTDCVVDITVTTIIVSALATTDTPPVTIMRSVRTRSTDYSRLAELDRLVQRITSGGVAVD QAHEAMDELTERPHPYPRWLATAGAAGFALGVAMLLGGTWLTCVLAAVTSGVIDRLGRLLNRIGTPLFFQ RVFGAGIATLVAVAAYLIAGQDPTALVATGIVVLLSGMTLVGSMQDAVTGYMLTALARLGDALFLTAGIV VGILISLRGVTNAGIQIELHVDATTTLATPGMPLPILVAVSGAALSGVCLTIASYAPLRSVATAGLSAGL AELVLIGLGAAGFGRVVATWTAAIGVGFLATLISIRRQAPALVTATAGIMPMLPGLAVFRAVFAFAVNDT PDGGLTQLLEAAATALALGSGVVLGEFLASPLRYGAGRIGDLFRIEGPPGLRRAVGRVVRLQPAKSQQPT GTGGQRWRSVALEPTTADDVDAGYRGDWPATCTSATEVR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3737 | - | - | 100% (529) | PROBABLE CONSERVED TRANSMEMBRANE PROTEIN |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3764 | - | 0.0 | 99.81% (529) | transmembrane protein |
| M. gilvum PYR-GCK | Mflv_0954 | - | 0.0 | 70.90% (512) | hypothetical protein Mflv_0954 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2127c | - | 4e-05 | 23.36% (214) | hypothetical protein MAB_2127c |
| M. marinum M | MMAR_3034 | - | 0.0 | 73.45% (516) | transmembrane protein |
| M. avium 104 | MAV_2919 | snm | 6e-06 | 23.85% (327) | secretion protein Snm4 |
| M. smegmatis MC2 155 | MSMEG_3459 | - | 0.0 | 72.22% (504) | hypothetical protein MSMEG_3459 |
| M. thermoresistible (build 8) | TH_0424 | - | 0.0 | 69.05% (517) | PROBABLE CONSERVED TRANSMEMBRANE PROTEIN |
| M. ulcerans Agy99 | MUL_2274 | - | 0.0 | 73.45% (516) | transmembrane protein |
| M. vanbaalenii PYR-1 | Mvan_5838 | - | 0.0 | 71.51% (530) | hypothetical protein Mvan_5838 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0954|M.gilvum_PYR-GCK ---MLPSPMVPSRQPRTPVPFRRASVSWPPMEPDSTPRFRRGLRIAMRGR
Mvan_5838|M.vanbaalenii_PYR-1 --------MGSDR-------------------SDGMARRRRALHFALKGR
Rv3737|M.tuberculosis_H37Rv ---------------------------MDQDRSDNTA-LRRGLRIALRGR
Mb3764|M.bovis_AF2122/97 ---------------------------MDQDRSDNTA-LRRGLRIALRGR
MMAR_3034|M.marinum_M MGGLAPRTVVAVVFAVRGSPSKISILPGVQDRLDGVAGSRRGLRIALRGR
MUL_2274|M.ulcerans_Agy99 ----------------------------MQDRLDGVAGSRRGLRIALRGR
MSMEG_3459|M.smegmatis_MC2_155 ----------------------------------------------MRGH
TH_0424|M.thermoresistible__bu ---------------------------MTQDRSTGRARLRGGLRLALRGT
MAB_2127c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_2919|M.avium_104 ----------------------MTAVVEVPQPDVEGISQPQAVVVGVMAG
Mflv_0954|M.gilvum_PYR-GCK RDPATGAGQRSRRPQNTSDERHTRKVLDLTVRLAEVMLSAGSGSADVVAT
Mvan_5838|M.vanbaalenii_PYR-1 RDPASGAGQR-RRTSGRLSERHTRKVLDLTIRLAEVMLSSGSGTADVVAT
Rv3737|M.tuberculosis_H37Rv RDPLPVAGRRSRTSGG-IDDLHTRKVLDLTIRLAEVMLSSGSGTADVVAT
Mb3764|M.bovis_AF2122/97 RDPLPVAGRRSRTSGG-IGDLHTRKVLDLTIRLAEVMLSSGSGTADVVAT
MMAR_3034|M.marinum_M RDPVPVAGQRSRTSSG-MGDQHVRKVLDLTIRLAEVMLSSGSGTADVVAT
MUL_2274|M.ulcerans_Agy99 RDPVPVAGQRSRTSSG-MGDQHVRKVLDLTIRLAEVMLSSGSGTADVVAT
MSMEG_3459|M.smegmatis_MC2_155 RDPAPVAGQRSRASAG-MGDLHTRKVLDLVIRLAEVMLSSGSGTADVVAT
TH_0424|M.thermoresistible__bu RDPAPGAGQR-RAAGG-LDELHTRKVLDLTIRLAEVMLSSGSGTADVVAT
MAB_2127c|M.abscessus_ATCC_199 -------------------------------------MGPAGG-------
MAV_2919|M.avium_104 AGVQIGVLLDANAPVSVMTEPLLKVVNSRLRELGETPLEATGRGRWALCL
: . .
Mflv_0954|M.gilvum_PYR-GCK AQDVAQAYRLNDCVVDVFVT-TVFVSAPPTTESPAVTIVRSVRARSTDYS
Mvan_5838|M.vanbaalenii_PYR-1 AQDVAQAYQLTDCVVDVFVT-TIFVSALPTADSPPVTIVRAVQARSTDYT
Rv3737|M.tuberculosis_H37Rv AQDVAQAYQLTDCVVDITVT-TIIVSALATTDTPPVTIMRSVRTRSTDYS
Mb3764|M.bovis_AF2122/97 AQDVAQAYQLTDCVVDITVT-TIIVSALATTDTPPVTIMRSVRTRSTDYS
MMAR_3034|M.marinum_M ANDVAQAYQITDCVVDITVT-TIIVSALPTAESAPVTIVRSVRTRSTNFT
MUL_2274|M.ulcerans_Agy99 ANDVAQAYQITDCVVDITVT-TIIVSALPTAESTPVTIVRSVRTRSTNFT
MSMEG_3459|M.smegmatis_MC2_155 AQDVAQAYRLTDCVVDITFT-TIIVSAPPTADSPPLTIMRAVRTRSTDYT
TH_0424|M.thermoresistible__bu AQDVAEAYQIKDCVVDITFT-TIIVSALPNADHPPVTIVRSVRTRSTDFT
MAB_2127c|M.abscessus_ATCC_199 --------------IDLTSG-ALLASAVELHS-----------FASISHA
MAV_2919|M.avium_104 VDGSPLRATQSLSEQDVYDGDRLWIRFIPDTEHRSQVIEHISTAVAANLS
*: : . : . :
Mflv_0954|M.gilvum_PYR-GCK R-LAALDELVRRITSGGVSVDQAHDAMDELSERPHPYPRWVATAGW----
Mvan_5838|M.vanbaalenii_PYR-1 R-LADLDRLVRRITSGGVSVDEAHEAMDELSEQPHPYPRWIATAGW----
Rv3737|M.tuberculosis_H37Rv R-LAELDRLVQRITSGGVAVDQAHEAMDELTERPHPYPRWLATAGA----
Mb3764|M.bovis_AF2122/97 R-LAELDRLVQRITSGGVAVDQAHEAMDELTERPHPYPRWLATAGA----
MMAR_3034|M.marinum_M R-LAELDRLVQEITAGGVTVDEAHEAMDELTQRPHPYPRWLATVCW----
MUL_2274|M.ulcerans_Agy99 R-LAELDRLVQEITAGGVTVDEAHEAMDELTQRPHPYPRWLATVCW----
MSMEG_3459|M.smegmatis_MC2_155 R-LAELDALIRDITSGGVSVDQAHAAMDVVTERPHPYPRWLSTAGW----
TH_0424|M.thermoresistible__bu R-LAALDRLVREITSGGVSVHQAHEAMDELSEQPHPYPRWLATAGW----
MAB_2127c|M.abscessus_ATCC_199 I-LDYLGTLAFAMSAALVAVEKKFDIVGLA--------------------
MAV_2919|M.avium_104 KRFAAIDPVVAVQVGATMVAVGVTAASGLLGWWRWHHNSWLPTVYAGVIG
: :. : .. : . .
Mflv_0954|M.gilvum_PYR-GCK -----AGFALGIAILLGGNWLVCLLAAATSAVIDQTGRRLNRAGTPLFFQ
Mvan_5838|M.vanbaalenii_PYR-1 -----AGFALGIAMLLGGTWLTCILAAGTSVLIDRSGRLLNRVGTPMFFQ
Rv3737|M.tuberculosis_H37Rv -----AGFALGVAMLLGGTWLTCVLAAVTSGVIDRLGRLLNRIGTPLFFQ
Mb3764|M.bovis_AF2122/97 -----AGFALGVAMLLGGTWLTCVLAAVTSGVIDRLGRLLNRIGTPLFFQ
MMAR_3034|M.marinum_M -----AGFSLGIAMMLGANWRTCAIAALTAATIDRLGRVLNRIGTPYFFQ
MUL_2274|M.ulcerans_Agy99 -----AGFSLGIAMMLGANWRTCAIAALTAATIDRLGRVLNRIGTPYFFQ
MSMEG_3459|M.smegmatis_MC2_155 -----AGFALGIAMLLGGSWLTCLVAALTSAAIDRTGRVLNRIGTPFFFQ
TH_0424|M.thermoresistible__bu -----AGFAFGIAMLMGGTWVTCFLAAFTSAVIDRVNRLLNRAGTPFFFQ
MAB_2127c|M.abscessus_ATCC_199 --------VLAMVTAIGG--------------------------------
MAV_2919|M.avium_104 VLMLGVSVLLLMRATTQQERRVGDTLLLSSLAPVSVAAAAAPPGGVGSPQ
: :
Mflv_0954|M.gilvum_PYR-GCK QVAGALIATLVAVAAYRLAGLGPTALVATGIVMLLSGMTLVGSVQDALTG
Mvan_5838|M.vanbaalenii_PYR-1 QAAGASIATLVAVAAFLFAGQGPTTLVATGIVMLLAGMTLVGSVQDALTG
Rv3737|M.tuberculosis_H37Rv RVFGAGIATLVAVAAYLIAGQDPTALVATGIVVLLSGMTLVGSMQDAVTG
Mb3764|M.bovis_AF2122/97 RVFGAGIATLVAVAAYLIAGQDPTALVATGIVVLLSGMTLVGSMQDAVTG
MMAR_3034|M.marinum_M RVTGAAVATLVAVAAYLFTGEGLAALVATGIVMLLSGLTLVGAMQDAITG
MUL_2274|M.ulcerans_Agy99 RVTGAAVATLVAVAAYLFTGEGLAALVATGIVMLLSGLTLVGAMQDAITG
MSMEG_3459|M.smegmatis_MC2_155 NVVGAAIATLVAVAAYLVTGEGLTALVATGIVMLLSGLTLVGSVQDAITG
TH_0424|M.thermoresistible__bu QVVGATIATVVAVAAYQYAGQGVTTLVATGIVVLLAGLTLVGSMQDALTG
MAB_2127c|M.abscessus_ATCC_199 -------GVLRDVIIGQHPPAAFTGFSHIGIALAAAGLVFLWQPPAKLTG
MAV_2919|M.avium_104 AVLGFGVLTIAAVLALRFTGRRLAIYTAIVTVSAIAALAALARMVAMTGA
.: * . : . :.:. : .
Mflv_0954|M.gilvum_PYR-GCK YMITAAARLGEVLFLTAGIVVG-ILAGLQVASLAGITIELQVDATEIMVL
Mvan_5838|M.vanbaalenii_PYR-1 YMLTAVARLGDVLFLTLGIVVG-ILAGLQIAALAGIQIQLRVDATEYFVV
Rv3737|M.tuberculosis_H37Rv YMLTALARLGDALFLTAGIVVG-ILISLRGVTNAGIQIELHVDATTTLAT
Mb3764|M.bovis_AF2122/97 YMLTALARLGDALFLTAGIVVG-ILISLRGVTNAGIQIELHVDATTTLAT
MMAR_3034|M.marinum_M YMVTAVARIGEALFLTSGIVVG-ILAGLQIAKTAGVEIELRVHGSGGFVV
MUL_2274|M.ulcerans_Agy99 YMVTAVARIGEALFLTSGIVVG-ILAGLQIAKTAGVEIELRVHGSGGFVV
MSMEG_3459|M.smegmatis_MC2_155 HMITAVARLSEALFMTAGIVVG-ILAGLQIATVAGVTIQLNVDATQAFVT
TH_0424|M.thermoresistible__bu HMITALARLGDAVFLTAGIVVG-ILAGLQIASLAGVEIQLRVDVGQTFVV
MAB_2127c|M.abscessus_ATCC_199 WPLQVTDALGLAVFCVTGTAIA-AHSGLAEPSAA----------------
MAV_2919|M.avium_104 VTLLTCVVLVSVLIYQSAPAISRRLAGIRLPVFPSATSRWVFEARPDLPT
: . : .:: . .:. .: .
Mflv_0954|M.gilvum_PYR-GCK PNQPASIAWAVFGATVAGACLTIASYARLRAVATAGLAAGLAELVLIALW
Mvan_5838|M.vanbaalenii_PYR-1 PTTPRQIVVAVSGAALAGACLVIASYAKWRSVLTAGVAAGLAEAVLIGLG
Rv3737|M.tuberculosis_H37Rv PGMPLPILVAVSGAALSGVCLTIASYAPLRSVATAGLSAGLAELVLIGLG
Mb3764|M.bovis_AF2122/97 PGMPLPILVAVSGAALSGVCLTIASYAPLRSVATAGLSAGLAELVLIGLG
MMAR_3034|M.marinum_M PQGPLPILLTVLGAMLAGACLTVASYAPLRSAVTAGFAAGLADLVLIGLG
MUL_2274|M.ulcerans_Agy99 PQGPLPILLTVLGAMLAGACLTVASYAPLRSAVTAGFAAGLADLVLIGLG
MSMEG_3459|M.smegmatis_MC2_155 PYRPGPIVLAVIGAAFASVCLTIASYAPWRTLLPAGLAAGFAEVVLIGLG
TH_0424|M.thermoresistible__bu PTEPRTITVAIVGSALAGICLTIACYTPMRSAPMTGVAAALATVVIFGVG
MAB_2127c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_2919|M.avium_104 TVVRSDGGPPVLEG--PASVRDVLTQAERARSFLSGLLIGLGVLMVVSLT
Mflv_0954|M.gilvum_PYR-GCK SGGLGSVIATGCAAVGVGFLATLISIR-RQAPALVTATAGITPMLPGMAV
Mvan_5838|M.vanbaalenii_PYR-1 RAGVGQVVATGTAAVGVGLLATLISIR-RQAPALVTATAGITPMLPGMAV
Rv3737|M.tuberculosis_H37Rv AAGFGRVVATWTAAIGVGFLATLISIR-RQAPALVTATAGIMPMLPGLAV
Mb3764|M.bovis_AF2122/97 AAGFGRVVATWTAAIGVGFLATLISIR-RQAPALVTATAGIMPMLPGLAV
MMAR_3034|M.marinum_M TAGFGQVIATGIAAVGVGFLATLISIR-RQALALVTATAGIVPMLPGLAV
MUL_2274|M.ulcerans_Agy99 TAGFGQVIATGIAAVGVGFLATLISIR-RQALALVTATAGIVPMLPGLAV
MSMEG_3459|M.smegmatis_MC2_155 WAGFGQVVATGVAAVGVGLFATLLSIR-RQAPALVTSTAGITPMLPGMAV
TH_0424|M.thermoresistible__bu AAGLGQIMATFVAAISVGLLATLVSIR-RQAPALVIATAGITPLLPGLAV
MAB_2127c|M.abscessus_ATCC_199 -------LLGAMTAIGGGVIRDLLSGE-TPMLLRPDSELYAVPAMLGASI
MAV_2919|M.avium_104 ALSDPRTGQRWLPVLLAGFCAGFLLLRGRSYVDRWQAITLAGTAVLIVGA
..: *. :: . : . : .
Mflv_0954|M.gilvum_PYR-GCK FRAVFYFAVEKDFAAGMTQAMVAAATALAIGAGVVMGELLGSPLRYRAGR
Mvan_5838|M.vanbaalenii_PYR-1 FRAVFYFAVERDFAAGMAQALAAAATALAIGAGVVMGELAGSPLRYRAGR
Rv3737|M.tuberculosis_H37Rv FRAVFAFAVNDTPDGGLTQLLEAAATALALGSGVVLGEFLASPLRYGAGR
Mb3764|M.bovis_AF2122/97 FRAVFAFAVNDTPDGGLTQLLEAAATALALGSGVVLGEFLASPLRYGAGR
MMAR_3034|M.marinum_M FRAVFYFAADSHFDEAQSQLLSAAATALALGSGVVLGEFVGSPLRYRAGR
MUL_2274|M.ulcerans_Agy99 FRAVFYFAADSHFDEAQSQLLSAAATALALGSGVVLGEFVGSPLRYRAGR
MSMEG_3459|M.smegmatis_MC2_155 FRAVYFFAVEDRFGDGLAQLLAAGATALALGAGVVLGEFIGSPLRYRAGR
TH_0424|M.thermoresistible__bu FRAVFAFAVEGRFNDGLAQLMTASAIALGIGSGVVLGELVGSPLRYGAGR
MAB_2127c|M.abscessus_ATCC_199 TALLIHVGLYTDLTGLAAALAAFGLRMLAMR-------------------
MAV_2919|M.avium_104 VVVRYALVLQSPLAVSISAAILVLVPVAGLTSAAVVPNTVYSPLFRKFVE
. : .:
Mflv_0954|M.gilvum_PYR-GCK IGQFLQVQGPPGLRRAVGRVVRLGPAEDQDATPASPYQRSWSVALEPLP-
Mvan_5838|M.vanbaalenii_PYR-1 ISDFLRVEGPPGLRRAVGNVVALRPAADQQSS-RSPHQRSWSVALEPEL-
Rv3737|M.tuberculosis_H37Rv IGDLFRIEGPPGLRRAVGRVVRLQPAKSQQPT-GTGGQRWRSVALEPTT-
Mb3764|M.bovis_AF2122/97 IGDLFRIEGPPGLRRAVGRVVRLQPAKSQQPT-GTGGQRWRSVALEPTT-
MMAR_3034|M.marinum_M IGHLLRIEGPPGLRRAVGRVVRLEPTKNAQST-NTRGQQSRSVALEPAS-
MUL_2274|M.ulcerans_Agy99 IGHLLRIEGPPGLRRAVGRVVRLEPTKNAQST-NTRGQQSRSVALEPAS-
MSMEG_3459|M.smegmatis_MC2_155 VGDFFRIEGPPGLRRAVGRVVRLRPAEDAPIT-GPLRRPIESVALEPEP-
TH_0424|M.thermoresistible__bu VGAFFRKDGPPGLRRGVGRVVRLRPSPAAPPQAGKLEPRLRSLPLEPESE
MAB_2127c|M.abscessus_ATCC_199 ----FHWHAPQARRRA----------------------------------
MAV_2919|M.avium_104 WIEYLCLMPIFPLALWLMNVYAAIRYR-----------------------
:
Mflv_0954|M.gilvum_PYR-GCK --------AEPALEGSHTDTP-----------------GTEDAPDAT---
Mvan_5838|M.vanbaalenii_PYR-1 --------SEVATEANGEDPA-----------------PERDATGER---
Rv3737|M.tuberculosis_H37Rv --------ADDVDAGYRGDWP-----------------ATCTSATEVR--
Mb3764|M.bovis_AF2122/97 --------ADDVDAGYRGDWP-----------------ATCTSATEVR--
MMAR_3034|M.marinum_M --------TDHSDAAEDNDRT-----------------GGHGGHGGHGGH
MUL_2274|M.ulcerans_Agy99 --------TDHSDAAEDNDRT-----------------GGHGGHGGHGGH
MSMEG_3459|M.smegmatis_MC2_155 --------TPSTTGDESEDTP-----------------RQDGGG------
TH_0424|M.thermoresistible__bu IEAEDAQADRPAAEAEPDDRPDSERPQPQDRLEDRADPGADDGAGQEPGK
MAB_2127c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_2919|M.avium_104 --------------------------------------------------
Mflv_0954|M.gilvum_PYR-GCK -------
Mvan_5838|M.vanbaalenii_PYR-1 -------
Rv3737|M.tuberculosis_H37Rv -------
Mb3764|M.bovis_AF2122/97 -------
MMAR_3034|M.marinum_M RDES---
MUL_2274|M.ulcerans_Agy99 RDES---
MSMEG_3459|M.smegmatis_MC2_155 -------
TH_0424|M.thermoresistible__bu NGEPPDR
MAB_2127c|M.abscessus_ATCC_199 -------
MAV_2919|M.avium_104 -------