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LPSPMVPSRQPRTPVPFRRASVSWPPMEPDSTPRFRRGLRIAMRGRRDPATGAGQRSRRPQNTSDERHTR KVLDLTVRLAEVMLSAGSGSADVVATAQDVAQAYRLNDCVVDVFVTTVFVSAPPTTESPAVTIVRSVRAR STDYSRLAALDELVRRITSGGVSVDQAHDAMDELSERPHPYPRWVATAGWAGFALGIAILLGGNWLVCLL AAATSAVIDQTGRRLNRAGTPLFFQQVAGALIATLVAVAAYRLAGLGPTALVATGIVMLLSGMTLVGSVQ DALTGYMITAAARLGEVLFLTAGIVVGILAGLQVASLAGITIELQVDATEIMVLPNQPASIAWAVFGATV AGACLTIASYARLRAVATAGLAAGLAELVLIALWSGGLGSVIATGCAAVGVGFLATLISIRRQAPALVTA TAGITPMLPGMAVFRAVFYFAVEKDFAAGMTQAMVAAATALAIGAGVVMGELLGSPLRYRAGRIGQFLQV QGPPGLRRAVGRVVRLGPAEDQDATPASPYQRSWSVALEPLPAEPALEGSHTDTPGTEDAPDAT*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0954 | - | - | 100% (555) | hypothetical protein Mflv_0954 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3764 | - | 0.0 | 70.90% (512) | transmembrane protein |
| M. tuberculosis H37Rv | Rv3737 | - | 0.0 | 70.90% (512) | transmembrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2861 | - | 6e-06 | 26.35% (334) | hypothetical protein MAB_2861 |
| M. marinum M | MMAR_3034 | - | 0.0 | 66.15% (517) | transmembrane protein |
| M. avium 104 | MAV_4944 | - | 6e-05 | 26.42% (246) | hypothetical protein MAV_4944 |
| M. smegmatis MC2 155 | MSMEG_3459 | - | 0.0 | 70.24% (504) | hypothetical protein MSMEG_3459 |
| M. thermoresistible (build 8) | TH_0424 | - | 0.0 | 64.95% (525) | PROBABLE CONSERVED TRANSMEMBRANE PROTEIN |
| M. ulcerans Agy99 | MUL_2274 | - | 0.0 | 66.15% (517) | transmembrane protein |
| M. vanbaalenii PYR-1 | Mvan_5838 | - | 0.0 | 75.82% (521) | hypothetical protein Mvan_5838 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0954|M.gilvum_PYR-GCK ---MLPSPMVPSRQPRTPVPFRRASVSWPPMEPDSTPRFRRGLRIAMRGR
Mvan_5838|M.vanbaalenii_PYR-1 --------MGSDR-------------------SDGMARRRRALHFALKGR
Mb3764|M.bovis_AF2122/97 ---------------------------MDQDRSDNTA-LRRGLRIALRGR
Rv3737|M.tuberculosis_H37Rv ---------------------------MDQDRSDNTA-LRRGLRIALRGR
MMAR_3034|M.marinum_M MGGLAPRTVVAVVFAVRGSPSKISILPGVQDRLDGVAGSRRGLRIALRGR
MUL_2274|M.ulcerans_Agy99 ----------------------------MQDRLDGVAGSRRGLRIALRGR
MSMEG_3459|M.smegmatis_MC2_155 ----------------------------------------------MRGH
TH_0424|M.thermoresistible__bu ---------------------------MTQDRSTGRARLRGGLRLALRGT
MAB_2861|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4944|M.avium_104 ----------------------MRWTRPGYALVLALLVVGPLLRPGYLLL
Mflv_0954|M.gilvum_PYR-GCK RDPATGAGQRSRRPQNTSDERHTRKVLDLTVRLAEVMLSAGSGSADVVAT
Mvan_5838|M.vanbaalenii_PYR-1 RDPASGAGQR-RRTSGRLSERHTRKVLDLTIRLAEVMLSSGSGTADVVAT
Mb3764|M.bovis_AF2122/97 RDPLPVAGRRSRTSGG-IGDLHTRKVLDLTIRLAEVMLSSGSGTADVVAT
Rv3737|M.tuberculosis_H37Rv RDPLPVAGRRSRTSGG-IDDLHTRKVLDLTIRLAEVMLSSGSGTADVVAT
MMAR_3034|M.marinum_M RDPVPVAGQRSRTSSG-MGDQHVRKVLDLTIRLAEVMLSSGSGTADVVAT
MUL_2274|M.ulcerans_Agy99 RDPVPVAGQRSRTSSG-MGDQHVRKVLDLTIRLAEVMLSSGSGTADVVAT
MSMEG_3459|M.smegmatis_MC2_155 RDPAPVAGQRSRASAG-MGDLHTRKVLDLVIRLAEVMLSSGSGTADVVAT
TH_0424|M.thermoresistible__bu RDPAPGAGQR-RAAGG-LDELHTRKVLDLTIRLAEVMLSSGSGTADVVAT
MAB_2861|M.abscessus_ATCC_1997 ---MTVAASEDRRWFG--------STEILVVALIAMALAAG-WLRGIVDA
MAV_4944|M.avium_104 RDAVSTPRSYLSDTALGLTAAPRAVPQDFAVALASHLLDGGVVVKTLLLL
. . :.: * * .* ::
Mflv_0954|M.gilvum_PYR-GCK AQDVA---QAYRLNDCVVDVFVTTVFVSAPPTTESPAVTI--VRSVRARS
Mvan_5838|M.vanbaalenii_PYR-1 AQDVA---QAYQLTDCVVDVFVTTIFVSALPTADSPPVTI--VRAVQARS
Mb3764|M.bovis_AF2122/97 AQDVA---QAYQLTDCVVDITVTTIIVSALATTDTPPVTI--MRSVRTRS
Rv3737|M.tuberculosis_H37Rv AQDVA---QAYQLTDCVVDITVTTIIVSALATTDTPPVTI--MRSVRTRS
MMAR_3034|M.marinum_M ANDVA---QAYQITDCVVDITVTTIIVSALPTAESAPVTI--VRSVRTRS
MUL_2274|M.ulcerans_Agy99 ANDVA---QAYQITDCVVDITVTTIIVSALPTAESTPVTI--VRSVRTRS
MSMEG_3459|M.smegmatis_MC2_155 AQDVA---QAYRLTDCVVDITFTTIIVSAPPTADSPPLTI--MRAVRTRS
TH_0424|M.thermoresistible__bu AQDVA---EAYQIKDCVVDITFTTIIVSALPNADHPPVTI--VRSVRTRS
MAB_2861|M.abscessus_ATCC_1997 NEKLA---TAG--------TVFCGVFVQAVP-------------------
MAV_4944|M.avium_104 GLWLAGWGAARLVALVLPGAGMPGEFVATTLAIWNPYVAERLLQGHWSLL
:* * . :* :
Mflv_0954|M.gilvum_PYR-GCK TDYSRLAALDELVRRITSGGVSVDQAHDAMDELSERPH----PYPRWVAT
Mvan_5838|M.vanbaalenii_PYR-1 TDYTRLADLDRLVRRITSGGVSVDEAHEAMDELSEQPH----PYPRWIAT
Mb3764|M.bovis_AF2122/97 TDYSRLAELDRLVQRITSGGVAVDQAHEAMDELTERPH----PYPRWLAT
Rv3737|M.tuberculosis_H37Rv TDYSRLAELDRLVQRITSGGVAVDQAHEAMDELTERPH----PYPRWLAT
MMAR_3034|M.marinum_M TNFTRLAELDRLVQEITAGGVTVDEAHEAMDELTQRPH----PYPRWLAT
MUL_2274|M.ulcerans_Agy99 TNFTRLAELDRLVQEITAGGVTVDEAHEAMDELTQRPH----PYPRWLAT
MSMEG_3459|M.smegmatis_MC2_155 TDYTRLAELDALIRDITSGGVSVDQAHAAMDVVTERPH----PYPRWLST
TH_0424|M.thermoresistible__bu TDFTRLAALDRLVREITSGGVSVHQAHEAMDELSEQPH----PYPRWLAT
MAB_2861|M.abscessus_ATCC_1997 -----FLALGVIVSGLVAT--------------FVTPE----RLARWLPN
MAV_4944|M.avium_104 VGYGCLPWVATAMLGLRTGGAGFFGLAFFIALAGLTPTGLLLAAAVALAC
: : : : : * . :.
Mflv_0954|M.gilvum_PYR-GCK AGWAGFALGIAILLGGNWLVCLLAAATSAVIDQTGRRL------NRAGTP
Mvan_5838|M.vanbaalenii_PYR-1 AGWAGFALGIAMLLGGTWLTCILAAGTSVLIDRSGRLL------NRVGTP
Mb3764|M.bovis_AF2122/97 AGAAGFALGVAMLLGGTWLTCVLAAVTSGVIDRLGRLL------NRIGTP
Rv3737|M.tuberculosis_H37Rv AGAAGFALGVAMLLGGTWLTCVLAAVTSGVIDRLGRLL------NRIGTP
MMAR_3034|M.marinum_M VCWAGFSLGIAMMLGANWRTCAIAALTAATIDRLGRVL------NRIGTP
MUL_2274|M.ulcerans_Agy99 VCWAGFSLGIAMMLGANWRTCAIAALTAATIDRLGRVL------NRIGTP
MSMEG_3459|M.smegmatis_MC2_155 AGWAGFALGIAMLLGGSWLTCLVAALTSAAIDRTGRVL------NRIGTP
TH_0424|M.thermoresistible__bu AGWAGFAFGIAMLMGGTWVTCFLAAFTSAVIDRVNRLL------NRAGTP
MAB_2861|M.abscessus_ATCC_1997 RSVA--AVAVAGIGGAALPGCECGSVP---VARRLYGP------GSVGAA
MAV_4944|M.avium_104 VPVAGAGRRRWVWAAAAIGAAAVAALPWLVAAVTGAALPSHTPANRLGVE
* . .. . .: . . *.
Mflv_0954|M.gilvum_PYR-GCK LFFQQVAG-----ALIATLVAVAAYRLAGLGPTALVATGIVMLLSGMTLV
Mvan_5838|M.vanbaalenii_PYR-1 MFFQQAAG-----ASIATLVAVAAFLFAGQGPTTLVATGIVMLLAGMTLV
Mb3764|M.bovis_AF2122/97 LFFQRVFG-----AGIATLVAVAAYLIAGQDPTALVATGIVVLLSGMTLV
Rv3737|M.tuberculosis_H37Rv LFFQRVFG-----AGIATLVAVAAYLIAGQDPTALVATGIVVLLSGMTLV
MMAR_3034|M.marinum_M YFFQRVTG-----AAVATLVAVAAYLFTGEGLAALVATGIVMLLSGLTLV
MUL_2274|M.ulcerans_Agy99 YFFQRVTG-----AAVATLVAVAAYLFTGEGLAALVATGIVMLLSGLTLV
MSMEG_3459|M.smegmatis_MC2_155 FFFQNVVG-----AAIATLVAVAAYLVTGEGLTALVATGIVMLLSGLTLV
TH_0424|M.thermoresistible__bu FFFQQVVG-----ATIATVVAVAAYQYAGQGVTTLVATGIVVLLAGLTLV
MAB_2861|M.abscessus_ATCC_1997 ALTFMLSA-----PAINPVVLVATAVAFPGQPRMVLARVVASLLTAMVMG
MAV_4944|M.avium_104 AFAPRAEPGLGTLTSLASLGGIWNADAVPGSRTTLFAVASAVVLLGVVAV
: . : .: : :.* . :* .:.
Mflv_0954|M.gilvum_PYR-GCK GSVQDALTGYMITAAARLGEVLFLTAGIVVGILAGLQVASLAGITIELQV
Mvan_5838|M.vanbaalenii_PYR-1 GSVQDALTGYMLTAVARLGDVLFLTLGIVVGILAGLQIAALAGIQIQLRV
Mb3764|M.bovis_AF2122/97 GSMQDAVTGYMLTALARLGDALFLTAGIVVGILISLRGVTNAGIQIELHV
Rv3737|M.tuberculosis_H37Rv GSMQDAVTGYMLTALARLGDALFLTAGIVVGILISLRGVTNAGIQIELHV
MMAR_3034|M.marinum_M GAMQDAITGYMVTAVARIGEALFLTSGIVVGILAGLQIAKTAGVEIELRV
MUL_2274|M.ulcerans_Agy99 GAMQDAITGYMVTAVARIGEALFLTSGIVVGILAGLQIAKTAGVEIELRV
MSMEG_3459|M.smegmatis_MC2_155 GSVQDAITGHMITAVARLSEALFMTAGIVVGILAGLQIATVAGVTIQLNV
TH_0424|M.thermoresistible__bu GSMQDALTGHMITALARLGDAVFLTAGIVVGILAGLQIASLAGVEIQLRV
MAB_2861|M.abscessus_ATCC_1997 ------------MVWSRWGRDSWVTR------------------------
MAV_4944|M.avium_104 GLPAVARRPAAVPLLVLAAAAVLIPAGLATGPGLRLLGAVVDAAP-----
. :.
Mflv_0954|M.gilvum_PYR-GCK DATEIMVLPNQPASIAWAVFGATVAGACLTIASYARLRAVATAGLAAGLA
Mvan_5838|M.vanbaalenii_PYR-1 DATEYFVVPTTPRQIVVAVSGAALAGACLVIASYAKWRSVLTAGVAAGLA
Mb3764|M.bovis_AF2122/97 DATTTLATPGMPLPILVAVSGAALSGVCLTIASYAPLRSVATAGLSAGLA
Rv3737|M.tuberculosis_H37Rv DATTTLATPGMPLPILVAVSGAALSGVCLTIASYAPLRSVATAGLSAGLA
MMAR_3034|M.marinum_M HGSGGFVVPQGPLPILLTVLGAMLAGACLTVASYAPLRSAVTAGFAAGLA
MUL_2274|M.ulcerans_Agy99 HGSGGFVVPQGPLPILLTVLGAMLAGACLTVASYAPLRSAVTAGFAAGLA
MSMEG_3459|M.smegmatis_MC2_155 DATQAFVTPYRPGPIVLAVIGAAFASVCLTIASYAPWRTLLPAGLAAGFA
TH_0424|M.thermoresistible__bu DVGQTFVVPTEPRTITVAIVGSALAGICLTIACYTPMRSAPMTGVAAALA
MAB_2861|M.abscessus_ATCC_1997 ----RLPHAHAGSSSRWATFAEAARHDFLQAASYLAIGAVAAAALHVLVP
MAV_4944|M.avium_104 ---GVGVLRDGQKWVALAVPGYALAGAGAVLTLRRRLFGAAAPALVCCLA
: . : ... ..
Mflv_0954|M.gilvum_PYR-GCK ELVLIALWSGGLGSVIATGCAAVGVGFLATLISIRRQAPALVTATAGITP
Mvan_5838|M.vanbaalenii_PYR-1 EAVLIGLGRAGVGQVVATGTAAVGVGLLATLISIRRQAPALVTATAGITP
Mb3764|M.bovis_AF2122/97 ELVLIGLGAAGFGRVVATWTAAIGVGFLATLISIRRQAPALVTATAGIMP
Rv3737|M.tuberculosis_H37Rv ELVLIGLGAAGFGRVVATWTAAIGVGFLATLISIRRQAPALVTATAGIMP
MMAR_3034|M.marinum_M DLVLIGLGTAGFGQVIATGIAAVGVGFLATLISIRRQALALVTATAGIVP
MUL_2274|M.ulcerans_Agy99 DLVLIGLGTAGFGQVIATGIAAVGVGFLATLISIRRQALALVTATAGIVP
MSMEG_3459|M.smegmatis_MC2_155 EVVLIGLGWAGFGQVVATGVAAVGVGLFATLLSIRRQAPALVTSTAGITP
TH_0424|M.thermoresistible__bu TVVIFGVGAAGLGQIMATFVAAISVGLLATLVSIRRQAPALVIATAGITP
MAB_2861|M.abscessus_ATCC_1997 TWVFEHLAGN-------LVVGVVTMALLAVVLALCSEADAFVAASITMMP
MAV_4944|M.avium_104 LILALPDLVWGVGGRVSPVRYPRGWPAVAAAINARPDAVAVLPAGTMRLF
: .*. : :* *.: :
Mflv_0954|M.gilvum_PYR-GCK MLPGMAVFRAVFYFAVEKDFAAGMTQAMVAAATALAIGAGVVMGELLGS-
Mvan_5838|M.vanbaalenii_PYR-1 MLPGMAVFRAVFYFAVERDFAAGMAQALAAAATALAIGAGVVMGELAGS-
Mb3764|M.bovis_AF2122/97 MLPGLAVFRAVFAFAVNDTPDGGLTQLLEAAATALALGSGVVLGEFLAS-
Rv3737|M.tuberculosis_H37Rv MLPGLAVFRAVFAFAVNDTPDGGLTQLLEAAATALALGSGVVLGEFLAS-
MMAR_3034|M.marinum_M MLPGLAVFRAVFYFAADSHFDEAQSQLLSAAATALALGSGVVLGEFVGS-
MUL_2274|M.ulcerans_Agy99 MLPGLAVFRAVFYFAADSHFDEAQSQLLSAAATALALGSGVVLGEFVGS-
MSMEG_3459|M.smegmatis_MC2_155 MLPGMAVFRAVYFFAVEDRFGDGLAQLLAAGATALALGAGVVLGEFIGS-
TH_0424|M.thermoresistible__bu LLPGLAVFRAVFAFAVEGRFNDGLAQLMTASAIALGIGSGVVLGELVGS-
MAB_2861|M.abscessus_ATCC_1997 LIPRLVFL--VVGPAVDVKLIAMQSGMFGRAFAARFAPLTFVVATLVAT-
MAV_4944|M.avium_104 SWSGPAPVLDPLPRWVRADVLSTGDLVISGTTIAGEGAHARAVQELLLSG
. . . . : * .: : :
Mflv_0954|M.gilvum_PYR-GCK --PLRYRAGRIGQFLQVQGPPGLRRAVGRVVRLGPAEDQDATPASPYQRS
Mvan_5838|M.vanbaalenii_PYR-1 --PLRYRAGRISDFLRVEGPPGLRRAVGNVVALRPAADQQSS-RSPHQRS
Mb3764|M.bovis_AF2122/97 --PLRYGAGRIGDLFRIEGPPGLRRAVGRVVRLQPAKSQQPT-GTGGQRW
Rv3737|M.tuberculosis_H37Rv --PLRYGAGRIGDLFRIEGPPGLRRAVGRVVRLQPAKSQQPT-GTGGQRW
MMAR_3034|M.marinum_M --PLRYRAGRIGHLLRIEGPPGLRRAVGRVVRLEPTKNAQST-NTRGQQS
MUL_2274|M.ulcerans_Agy99 --PLRYRAGRIGHLLRIEGPPGLRRAVGRVVRLEPTKNAQST-NTRGQQS
MSMEG_3459|M.smegmatis_MC2_155 --PLRYRAGRVGDFFRIEGPPGLRRAVGRVVRLRPAEDAPIT-GPLRRPI
TH_0424|M.thermoresistible__bu --PLRYGAGRVGAFFRKDGPPGLRRGVGRVVRLRPSPAAPPQAGKLEPRL
MAB_2861|M.abscessus_ATCC_1997 --GIGLAVLGAS--------------------------------------
MAV_4944|M.avium_104 PDPAALAAAGVGWLVLEADSAGEVGAAAHTLGAAAPVYRDDEIALYRIGG
. .
Mflv_0954|M.gilvum_PYR-GCK WSVALEPLP---------AEPALEGSHTDTP-----------------GT
Mvan_5838|M.vanbaalenii_PYR-1 WSVALEPEL---------SEVATEANGEDPA-----------------PE
Mb3764|M.bovis_AF2122/97 RSVALEPTT---------ADDVDAGYRGDWP-----------------AT
Rv3737|M.tuberculosis_H37Rv RSVALEPTT---------ADDVDAGYRGDWP-----------------AT
MMAR_3034|M.marinum_M RSVALEPAS---------TDHSDAAEDNDRT-----------------GG
MUL_2274|M.ulcerans_Agy99 RSVALEPAS---------TDHSDAAEDNDRT-----------------GG
MSMEG_3459|M.smegmatis_MC2_155 ESVALEPEP---------TPSTTGDESEDTP-----------------RQ
TH_0424|M.thermoresistible__bu RSLPLEPESEIEAEDAQADRPAAEAEPDDRPDSERPQPQDRLEDRADPGA
MAB_2861|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4944|M.avium_104 HTAGVAADRRAATLIAHLAWLVLLLGSGAGVLLG-------------AWW
Mflv_0954|M.gilvum_PYR-GCK EDAPDAT----------
Mvan_5838|M.vanbaalenii_PYR-1 RDATGER----------
Mb3764|M.bovis_AF2122/97 CTSATEVR---------
Rv3737|M.tuberculosis_H37Rv CTSATEVR---------
MMAR_3034|M.marinum_M HGGHGGHGGHRDES---
MUL_2274|M.ulcerans_Agy99 HGGHGGHGGHRDES---
MSMEG_3459|M.smegmatis_MC2_155 DGGG-------------
TH_0424|M.thermoresistible__bu DDGAGQEPGKNGEPPDR
MAB_2861|M.abscessus_ATCC_1997 -----------------
MAV_4944|M.avium_104 RRGVSRAR---------