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M. marinum M MMAR_3099 (-)

annotation: polyketide synthase and peptide synthetase
coordinates: 3772823 - 3781318
length: 2831

SLILDRVRELGTQIPDAAALSFVNDRGLVTESMSRVDVVTEMNKVAQFVRQDCGLAPGDRAVLVYPPGLD
FVCGLLGCMAAGVIAVPVFPPDPINPQKSGAAFRRVALDCGATAVLTSHHYADARQLEVAAPVGTAFDED
WPNALPWHVTSRGASGRGKSAPRAVSEAISEWAPSPQTPALLQYTSGSTSDPKGVVITHGNVVHQAEFNR
RFIGLGPGHRAVFWVPPYHDFGLISGILSALAGNFDLTMMSPMSFIQRPALWFEVMDRVRATVTVAPNFG
FELAMRKTTAEQRAGWDLSPLQVIVSAAEPVREDTTRRFFEAFAASGIRREAFCPCYGLAEHTVGITVSG
RSSLRVDRSQLEARQLAVPSDAPDAQVLMGCGQPTDDVDVRIVDPELCVPLGDGQVGEIWADSPSKAAGY
WGLSAKSRATFQAALAGVEGGRGYLRTGDLGFLHDGELYVCGRIKDLLILAGRNIYPQDIEDSLRDCHPA
IRPGGFAAFAVVDGNSETLAVLVEVRTDGSPDLLAGVVAAIRAAVLKDHQLRCGVVVLGPPGSVSKTTSG
KVQRSRCRARFLDGTLQAQALLVDRRTDDEPVGAAPTTEQLLSVVCGQAAEVLGIGAASVDIDRSLGDQG
LNSIGVTELASRLTQVLGQDVQPVDIFNHPTVGDLVQILSPGEKTRHQRGVRERLGHHAASGAGAVALPA
DPVAIVGIGCRFPGGVDSADSLWDMVVSARDVISDFPGDRGWDAGRLFDPDPDALGKTYCAVGGFLEDAA
GFDAGFFGIAPREALAMDPQQRVLLEVSWEALEDAGIDPKALRGSATGVFVGTWAQPYGDGGSDSADGYA
MTGTATSVASGRVAYVLGLEGPAVSVDTACSSSLVAVHQAVQSLRLGECDLALAGGVTVMATPSVFVGFS
RQRGLAPDGRCKAFAEAADGVGWGEGAGVLVLQRLSDARRQGRVVLGVVRGSAVNQDGASHGLTAPNGPA
QQRVIRAALAGAGLGPADVDVVEAHGTGTRLGDPIEAQALLAVYGQDREPGRPLWVGSIKSNMGHAQAAA
GVAGVIKMVQAMRHGLLPETLHVDEPSGQVDWSAGAVEVLSRARSWLGVPGRPRRAGVSSFGISGTNAHV
IVEQALPEVAESGGVSGVCGQGVGSVESVVRASVVPWVLSAQSRQALVAQASRLLGRVGGDDGLDPVDVG
LSLAQRCVFEHRAVVVGRDREALLAGLTGLARGGPGAGVVVGQAAAVGKTVLVFPGQGAQWTGMGRGLHG
QFPAFARAFDAAVDELDQHLPMPLREVMWGTDKGLLDSTEFAQPALFALEVGLWALLEHWGIRPDFVLGH
SVGELSAAHVAGVLSLADAAMLVAARGRLMQGLPAGGVMVALGVGEQEVDPLLAESAHPVSIAAINAPEQ
VVISGAQAAVMTIADQLAARGHRVQQLAVSHAFHSPLMEPIVEEFAEIAGRVTVEAPRIGVISNLTGELA
GPGYGSKAYWREHIRRPVRFSDSVACARAQGATHFVEAGPGAGLTAAIEQSLGSVAATVVAVLGKQRPEP
DSLLDAAAQLFASGARLDWPAVFLGWGGRRVSLPTYAFMRQRFWLTPHLAGSVGAAELGSGNPRHPLLDA
VVEHPDSGEVILAGRLSRRAQPWLADHVIGGLVLLPGTGFVELVIRAGDQLGCAAIDELTLTNPLIVPDG
SEVQVQVVVGAAERSGRRTVSVYSRADHIGAAWVQHAEGALGVDPMPASGDFSVWPPSGAEAVRVSDAYE
RLAQLGYRYGPAFRGIEAIWRRGTEVYAEVAIPADAELGINGYGIHPVLLDAVLQAAAVAVDSGDTRLPY
SWRGISLHAAAAKRIRARIAPVGEVGYAVECADVAGLPVLTMGSLVTRPVSAEQLHAGAATAIGRPAQGL
LELAWSPISPAHGALDGGGHQTVLSWADFTAGAAAAADGVGGRAVAVVWESRTAETDVVGSVYARIHAAL
SVLQHWLAQDQLASLVVVTHGAVGLPGEAITDLAGSAVWGLARSAQAESPGRIVLVDIDTPNTPDLGVLL
AGREPQLVVRGDSVFCARLRPVEAPLEVPVGQSAWQLSTGGGGTLADIVVQPCPPAQAPLEPGQVRVAVA
AAGVNFRDVLMALGMYPGAQPVLGGEGSGVVLEVGPQVSGVGVGDAVMGLIAGVGPLAVVDARLLVRVPS
GWSLAEAAGVPVAFLTAWYGLADLAGVRAGESVLVHAGTGGVGMAAVQLARLWGAKVFVTASRGKWDTLR
SMGFDDSRIGDSRSLEFAEKFFAATRGRGVDVVLNSLAGEFVDASLRLLAPGGRFIEMGKTDIRDPQQIA
VEYPGVIYEAFDLIEAGPARIQPMLGQLHTLFEASALESLPTRTWDARCAPAAYRFVSQARQIGKVVLTM
PTQISDAVAAGTVLITGGTGMVASVLARHLVSSYGVKHVVLASRRADATAGVAELVADLAAAGAAVAVVA
CDVADRAAVTRLLDHVSTCHPPLTGVIHAAGTLDDAVIASLTPDRVDAVLRAKVDGAWNLHEATRHLGLS
MFVLCSSIAATVGSSGQANYAAGNAFLDGLAAYRRAGGLPGMSLGWGLWEQSSTMTAHLSDRDMARIRRI
GLAAISPEQAMQLFDAALAVGQPTVLAAHLDHAVLANHTLSSTLPPLFSTLIKRPLRRLVDNDTPSSTAG
FAQRLYGLKPEKQQDLLVDLVCTQAAAVLGHPSATDLNPASTFQNMGFDSLTAVELRNRLKTVTGLGLSP
TLVFDHPTPTALAGLIAELIGIAAKGLSPLEEALNNVEETLPAIEAGDKHRVADRLRALLSTITDEEHRL
DERIQAASTLDEVLLLVDSELANLEKGPGL*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_3099--100% (2831)polyketide synthase and peptide synthetase
M. marinum MMMAR_3098-0.066.32% (2102) polyketide synthase PKS
M. marinum MMMAR_1762pks15/10.063.09% (2081) polyketide synthase Pks15/1

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2971cpks10.065.74% (2058) polyketide synthase PKS1
M. gilvum PYR-GCKMflv_0405-0.037.36% (2262) beta-ketoacyl synthase
M. tuberculosis H37RvRv2048cpks120.055.72% (2272) polyketide synthase pks12
M. leprae Br4923MLBr_00135-0.064.13% (2060) putative polyketide synthase
M. abscessus ATCC 19977MAB_0939-0.036.64% (2276) polyketide synthase
M. avium 104MAV_3108-0.059.09% (2112) erythronolide synthase, modules 3 and 4
M. smegmatis MC2 155MSMEG_0408-0.036.89% (2247) type I modular polyketide synthase
M. thermoresistible (build 8)TH_4458-0.039.74% (1364) PUTATIVE putative Fatty acyl-AMP ligase FadD28_1 and polyketide
M. ulcerans Agy99MUL_2005pks15/10.062.81% (2081) polyketide synthase Pks15/1
M. vanbaalenii PYR-1Mvan_1003-0.036.42% (2474) beta-ketoacyl synthase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0405|M.gilvum_PYR-GCK          ----------------------MGSAAHQGE-SAHRFAIVGYAGRFPG-A
MAB_0939|M.abscessus_ATCC_1997      ----------------------MDSAENPIE-STPRFAIIGYAARFPG-A
MSMEG_0408|M.smegmatis_MC2_155      ----------------------MVSAEHPIE-PTPSFAIIGYAARFPG-A
Mvan_1003|M.vanbaalenii_PYR-1       --------MTDLQKRALQAIEVLRARVRELEGAGDGYAIVGYALRFPG-A
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MMAR_3099|M.marinum_M               --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        MVDQLQHATEALRKALVQVERLKRTNRALLERSSEPIAIVGMSCRFPGGV
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          RDAESFWELLADGRDAISEVPEDR-WDVEAFFDPDPSTPGKVVTRRAGFV
MAB_0939|M.abscessus_ATCC_1997      ADAEEFWDVLREGRDAISEVPADR-WDAEEFFDPEPGAPGKVVTRRAGFV
MSMEG_0408|M.smegmatis_MC2_155      ASAEEYWALLRDGREAISDVPKDR-WDIEEFFDPDPSTPGKVVTRRAGFV
Mvan_1003|M.vanbaalenii_PYR-1       ADADEFWDVLRGGRDAISEVPQDR-WDADEFFDADPEAAGKMVTRRAGFV
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MMAR_3099|M.marinum_M               --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        DSPEGLWQMVADARDVMSEFPTDRGWDLAGLFDPDPDVRHKSYARTGGFV
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          DDVSGFDAPFFGMSTREVRLMDPQHRLLLETAWRAIEHSGTAPSELANTN
MAB_0939|M.abscessus_ATCC_1997      EDVTGFDAPFFGMSTREVRLMDPQHRLLLETAWRAVEHSGIAPTDLAETN
MSMEG_0408|M.smegmatis_MC2_155      DDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSN
Mvan_1003|M.vanbaalenii_PYR-1       EDVAGFDAPFFGVSAREAMFMDPQHRLLLETAWRAVEHSGTAPSALAGTR
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MMAR_3099|M.marinum_M               --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        DGVADFDPAFFGISPSEALAMDPQHRMLLELSWEALERAGIDPTGLRGSA
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          TGVFVGLATHDYLGMASDELSYPEIEAYMAIGTSNAAAAGRISYRLGLQG
MAB_0939|M.abscessus_ATCC_1997      SGVFVGLATHDYLGMASDELTFPEIEAYMAIGTSNAAAAGRISYRLGLQG
MSMEG_0408|M.smegmatis_MC2_155      TGVFVGLATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQG
Mvan_1003|M.vanbaalenii_PYR-1       TGVFMGLSTHDYLGMLTDNLTHDAIEAYLGTGTSPAAAIGRISYRLGLQG
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MMAR_3099|M.marinum_M               --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        TGVFAGLIVGGYG------MLAEEIEGYRLTGMTSSVASGRVAYVLGLEG
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          PAVAVDTACSSSLVAIHQACQALRLGECDLALAGGANVILTPATMITFSN
MAB_0939|M.abscessus_ATCC_1997      PSVAVDTACSSSLVAIHQACQALQLGECDLALAGGANVLLTPATMITFSH
MSMEG_0408|M.smegmatis_MC2_155      PAVAVDTACSSSLVAIHQACQALRLNECDLALAGGANVLLTPATMITFSN
Mvan_1003|M.vanbaalenii_PYR-1       PAVAVDTACSSSLVAVHQACQALRLAECDVALAGGVNVLLSPATMINFSR
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MMAR_3099|M.marinum_M               --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        PAVSVDTACSSSLVALHMAVGSLRSGECDLALAGGVTVNATPTVFVEFSR
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          AHMLAPDGRCKTFDAAADGYVRGEGCGVIVIKRLEDAVRDGDRIRAVIRG
MAB_0939|M.abscessus_ATCC_1997      AHMLAPDGKCKTFDAAADGYVRGEGSGVIVIKRLEDAIRDGDRIRAVIRG
MSMEG_0408|M.smegmatis_MC2_155      AHMLAPDGRCKTFDAAADGYVRGEGCGVVVVKRLEDAVRDGDRIRAVIRG
Mvan_1003|M.vanbaalenii_PYR-1       ARMLAPDGRCKTFDATADGYVRGEGCGVVVVKRLADAIRHGDRIRAVIRG
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MMAR_3099|M.marinum_M               --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        HRGLAPDGRCKPYAGRADGVGWSEGGGMLVLQRLSDARRLGHPVLAVVVG
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          SAINQDGASGGLTVPNGVAQQRVIGDALSRAGLAPGDVDYLEAHGTGTSL
MAB_0939|M.abscessus_ATCC_1997      SAINQDGASGGLTVPNGVAQQRVIADALKRAGVAPSEVGYLEAHGTGTSL
MSMEG_0408|M.smegmatis_MC2_155      SAINQDGASGGLTVPNGVAQQRVIADALKRAGLRPADVGYLEAHGTGTSL
Mvan_1003|M.vanbaalenii_PYR-1       SAVNQDGASGGLTVPNGAAQQRVIADALTNAGLTAADVDYLEAHGTGTPL
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MMAR_3099|M.marinum_M               --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        SAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTTL
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          GDPIEAQAAGAALGPGR-EPQRPLLIGSAKTNIGHLEAAAGIAGVIKVVL
MAB_0939|M.abscessus_ATCC_1997      GDPIEAQAAGAAYGIGR-ETNDPLLIGSAKTNIGHLEAAAGIAGVIKVIL
MSMEG_0408|M.smegmatis_MC2_155      GDPIEAQAAGEVLGAGR-APEEPLLIGSAKTNIGHLEAAAGIAGVIKVVM
Mvan_1003|M.vanbaalenii_PYR-1       GDPIEVQAAGAVLGVGR-EPDRPLLIGSVKTNIGHLEAASGIAGLLKVIL
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MMAR_3099|M.marinum_M               --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        GDPIEAQALLATYGQDRGEPGEPLWLGSVKSNMGHTQAAAGVAGVIKMVL
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          SLEHETLPKHLNFENPSPHIPWDRLPVEVVKESIPWRRGQRGGRPRIAGV
MAB_0939|M.abscessus_ATCC_1997      SLENELLPQHRNFQNPSPHIPWDRLPVEVVREARPWGR---NGRPRIAGV
MSMEG_0408|M.smegmatis_MC2_155      ALENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQR---NGKPRIAGV
Mvan_1003|M.vanbaalenii_PYR-1       SLEHQVLPKHLNFRSPSPHIPWNRLPVRIVDDPVPWTR---SGRSRVAGI
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MMAR_3099|M.marinum_M               --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        AMRHELLPATLHVDVPSPHVDWSAGAVELLTAPRVWPAG---ARTRRAGV
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          SSFGFAGTNAHVILEEAPLAAEPAQES---VDDGRFTLLPLSARTPAALM
MAB_0939|M.abscessus_ATCC_1997      SSFGFAGTNAHVILEEAPVVSRDAVEPPAPAGGRKFSILPLSARTPAALA
MSMEG_0408|M.smegmatis_MC2_155      SSFGFAGTNAHVILEEAPAVGTPATTEP-VEDPRRYSVLPLSARTPEALV
Mvan_1003|M.vanbaalenii_PYR-1       SSFGFSGTNAHVLVEEAPRADRAGAAPQ-PAAPGGFGMLPLSARTPDALA
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MMAR_3099|M.marinum_M               --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        SSFGISGTNAHVIIEAVPVVPRREAGWA-----GPVVPWVVSAKSESALR
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          AVADRYRDWLVANPDATLADLCFTAGTARSHLEHRAALVVNTREAALDLL
MAB_0939|M.abscessus_ATCC_1997      QLADKYRAWLNAHPEAALADLCFTAGVGRAHLEHRAALVVNTREAAVELL
MSMEG_0408|M.smegmatis_MC2_155      RLAGEYRDWLRAHPQARLADVSHTAGTARAHLEQRAALVVNSRESAIELL
Mvan_1003|M.vanbaalenii_PYR-1       ATAHRLRTWLAANPDASWPDLCFTAAVGRSHLRHRAALVVDSRSSVEELL
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MMAR_3099|M.marinum_M               --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        GQAARLAAYVRGDDGLDVADVGWSL-AGRSVFEHRAVVVGGDRDRLLAGL
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          GALADDRPAPGLVRGESHDTPKTAWLFTGQGSQYPGMSRELFDTEPLFAE
MAB_0939|M.abscessus_ATCC_1997      SAVADDRPAPGLGRGESHDTPKTAWLFTGQGSQYPGMARELFETEPVFAD
MSMEG_0408|M.smegmatis_MC2_155      GALADDRPAPGLVRGESHEAPKTAWLFTGQGSQYPGMARELFDTEPVFAE
Mvan_1003|M.vanbaalenii_PYR-1       GALAEDRPGPGLARGECGDPPKTAWLFTGQGSQYPGMGRELFDTEPVYRE
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MMAR_3099|M.marinum_M               --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        DELAGDQLGGSVVRGTATAAGKTVFVFPGQGSQWLGMGIELLDTAPAFAQ
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          TLRECAAAVDGMLEKPLLDVIFDTDGVLDTDSNETLRHTSYAQPALFAVE
MAB_0939|M.abscessus_ATCC_1997      TLNRCAAAVADVLEKPLLDVIFDVD---GPEAEETLRQTSYAQPALFAVE
MSMEG_0408|M.smegmatis_MC2_155      TVRKCAEAVADILEKPLLDVIFDAD-ELDGDTESPLRHTTYAQPALFAVE
Mvan_1003|M.vanbaalenii_PYR-1       VMTRCAEAVADVLERPLLDVVFDAD------GGEALRHTSYAQPALYAVE
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MMAR_3099|M.marinum_M               --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        QIDACAEAFAEFVDWSLVDVLRGAP------GAPGLDRVDVVQPVLFAVM
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          MGLARLWQSWGFEPDVVLGHSVGQYAAACVAGVLSLRDGARLMAERGRLF
MAB_0939|M.abscessus_ATCC_1997      MGLARLWQSWGFEPDVVLGHSVGQYSAACVAEVFSLEDGARLIAERGRLF
MSMEG_0408|M.smegmatis_MC2_155      LGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGARLIAERGRLF
Mvan_1003|M.vanbaalenii_PYR-1       MGLARLWQSWGIEPDVVLGHSVGQYAAACVAGVMGLEDGAVLLAERGRLF
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MMAR_3099|M.marinum_M               --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        VSLAELWKSVAVHPDAVIGHSQGEIAAAYVAGALSLRDAARVVTLRSKLL
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          GSLPSGGRMAAVFAAAERVEALTDEYPALS--VAAYNGANTVLSGPATDL
MAB_0939|M.abscessus_ATCC_1997      SSLPAGGRMAAVFTDAERAERLTDEFPSLS--VAAYNGANTVLSGPAQDL
MSMEG_0408|M.smegmatis_MC2_155      GSLPAGGRMAAVFTAPERAERLTDEYPSLS--VAAYNGANTVLSGPAKDL
Mvan_1003|M.vanbaalenii_PYR-1       GSLPEGGRMAAVFAPADRVESCTVDSPLLS--VAAYNGDNTVLSGPAGDL
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MMAR_3099|M.marinum_M               --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        AGLAGPGGMVSIACGADQARDLLAPFGDRVSIAVVNGPSAVVVSGEVGAL
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          ERAVAGLVADGVRCDWLETSHAFHSALLDPILDDFESYARGITFTAPQRI
MAB_0939|M.abscessus_ATCC_1997      EKAIAALVADGVRCDFLETSHAFHSALLDPILDEFEAYANQFNYKTPQRI
MSMEG_0408|M.smegmatis_MC2_155      ESAVATLVADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRI
Mvan_1003|M.vanbaalenii_PYR-1       ERAVAGFSAAGVRCDWLDTSHAFHSALLDPVLEEFESCADRFEFGTPQRT
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MMAR_3099|M.marinum_M               --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        EELIAVCSTKELRTRRIEVDYASHSVEVEAIRGPLAEALSGIEPRSTRTV
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          LIDNRTGAALGRSVTLDAAYWRRHARQPVEFAKSVH--------------
MAB_0939|M.abscessus_ATCC_1997      LIDNRTGTALGRSVKLDGAYWRRHARQPVEFAKSVR--------------
MSMEG_0408|M.smegmatis_MC2_155      LIDNRTGSALGRSTRLDGAYWRRHARQPVEFAKSVR--------------
Mvan_1003|M.vanbaalenii_PYR-1       LVCNRSGEVLSRHARLDGQYWRRHARQPVRFAESVR--------------
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MMAR_3099|M.marinum_M               --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        FFSTVTGNRL-DTAGLDADYWYRNVRQTVLFDQAVRNACEQGYRTFIESS
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MMAR_3099|M.marinum_M               --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        PHPALITGVEETFAACTDGDSEAIVVPTLGRGDGGLHRFLLSAASAFVAG
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MMAR_3099|M.marinum_M               --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        VAVNWRGTLDGAGYVELPTYAFDKRRFWLSAEGSGADVSGLGLGASEHPL
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MMAR_3099|M.marinum_M               --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        LGAVVDLPASGGVVLTGRLSPNVQPWLADHAVSDVVLFPGTGFVELAIRA
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MMAR_3099|M.marinum_M               --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        GDEVGCSVLDELTLAAPLLLPATGSVAVQVVVDAGRDSNSRGVSIFSRAD
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MMAR_3099|M.marinum_M               --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        AQAGWLLHAEGILRPGSVEPGADLSVWPPAGAVTVDVADGYERLATRGYR
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MMAR_3099|M.marinum_M               --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        YGPAFRGLTAMWARGEEIFAEVRLPEAAGGVGGFGVHPALLDAVLHAVVI
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MMAR_3099|M.marinum_M               --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        AGDPDELALPFAWQGVSLHATGASAVRARIAPAGPSAVSVELADGLGLPV
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MMAR_3099|M.marinum_M               --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        LSVASMVARPVTERQLLAAVSGSGPDRLFEVIWSPASAATSPGPTPAYQI
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          -TLADMNCKLLVEIGPRPVLTAAALSAWPDPATSPRVIASLRRTTADQRQ
MAB_0939|M.abscessus_ATCC_1997      -TLADMNCKVLLEIGPQPVLTAAALRAWPDPATAPRAIASLRRNTADHRQ
MSMEG_0408|M.smegmatis_MC2_155      -TLADMNCRVLLEIGPRPVLTATALAAWPDPATTPQVLASLRPTTADHRQ
Mvan_1003|M.vanbaalenii_PYR-1       -TLADLGCRLLMEIGPQPVLTAAAMRTWPGTVTAPRVAASMRRKGSDRRQ
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MMAR_3099|M.marinum_M               -MSLILDRVRELGTQIPDAAALSFVNDRGLVTES------------MSRV
MAV_3108|M.avium_104                --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        FESVAADQDPVAGSYVRSHQALAAVQSWLTDHESGVLVVATRGAMALPRE
TH_4458|M.thermoresistible__bu      -------------------LLSLLRQRSERYGDKIAFDYCTGEQEHSRLT
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          ITEAVADAYVLGHLPRFAAFRRDGARVLDLPTYPFEH---RQYWFSDSRE
MAB_0939|M.abscessus_ATCC_1997      ITEAAADAYVLGHLPDFGAFQHAPARKLDLPTYPFER---RQYWFSDKRD
MSMEG_0408|M.smegmatis_MC2_155      ITEAVAAAYAAGHLPDFRAFRQPDARKLDLPTYPFEH---RQFWFSDNRA
Mvan_1003|M.vanbaalenii_PYR-1       ITEALAQAYVAGHRPETAARQHGRGRLLDLPTYPFQH---RAYWFP----
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MMAR_3099|M.marinum_M               DVVTEMNKVAQFVRQDCGLAPGDRAVLVYPPGLDFVCGLLGCMAAG----
MAV_3108|M.avium_104                --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        DVADLAGAAVWGLVRSAQTEHPGRIVLVDSDAATDDAAIAMALATGEPQV
TH_4458|M.thermoresistible__bu      YQELDIRARAIAAHLQDQGVAGERVLVLCPSGLDFITAMFGCFYVG----
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          ---PVAAAPQR---GARTETVRLLEDGRIEELAALLGGTVDDPFTFDVLN
MAB_0939|M.abscessus_ATCC_1997      GDNRDAGNRQQNNGGPRTEAVRLLEDGKIEELANLLGGVDGDQQTLNVLT
MSMEG_0408|M.smegmatis_MC2_155      IDRDTQTASAGSVTPHRTQAVRLLEDGQIEELAALIDGETVDEQTLRVLN
Mvan_1003|M.vanbaalenii_PYR-1       ----QGQARTAPTDPVHTETVRFLDEERIDELAALLDGPTGSAQTVDVLS
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MMAR_3099|M.marinum_M               ---------------VIAVPVFPPDPINPQKSGAAFRRVALDCGATAVLT
MAV_3108|M.avium_104                --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        VLRGGQVYTARVRGSRAADAILVPPGDGPWRLGLGSAGTFENLRLEPVPN
TH_4458|M.thermoresistible__bu      ------------------AVAVPVHPPVHNRLLSRVASIVADVRATSVLT
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          RLAAQHNQQRSTESIADDRYQIRWETAAEPPVGADAADGITWLLVGDDTD
MAB_0939|M.abscessus_ATCC_1997      KLAAQHNLQRTTQTIADDRYQFRWEKSPTPLSGSQAAGGVTWLLVADAAG
MSMEG_0408|M.smegmatis_MC2_155      KLAARHNQQRSTHVDPDARYEIRWDAIASAAASTGAAA--DWILVGDDTA
Mvan_1003|M.vanbaalenii_PYR-1       KLAARHRQQRGAQSIADARYQIRWEKSEAPGAARPTTEATTWLLVTHDSR
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MMAR_3099|M.marinum_M               SHHYADARQLEVAAPVGTAFDEDWPNALPWHVTSRGASGRGKSAPRAVSE
MAV_3108|M.avium_104                --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        ADAPLGPGQVRVAMRAIAANFRDIMITLGMFTHDALLGGEGAGVVVEVGP
TH_4458|M.thermoresistible__bu      TAATRADLKEILDGLHDG------DPLRWLAVDTIEADDETSWTPTTVDT
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          ATRPLVDVLAARGHRYRILGLPKSG-------------------------
MAB_0939|M.abscessus_ATCC_1997      AAQPLLDVLTARGQQHRVLALPVSD-------------------------
MSMEG_0408|M.smegmatis_MC2_155      AVLEFADALTAGGHRHQIVALPGSD-------------------------
Mvan_1003|M.vanbaalenii_PYR-1       AAQPIAEVLERRGHPYHIVGLPGSD-------------------------
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MMAR_3099|M.marinum_M               AISEWAPSPQTPALLQYTSGSTSDPKGVVITHG-----------------
MAV_3108|M.avium_104                --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        GVTEFSVGDSVFGFFPDGSGTLVAGDVRLLLPMPADWSYAEAAAISAVFT
TH_4458|M.thermoresistible__bu      DSVAFVQYTSGSTSTPKGVVLTHHN-------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          ---------AEEHELADTLRDAAADATDLRIVHVAALDAAESDTSMKSLL
MAB_0939|M.abscessus_ATCC_1997      ---------ADEAELVEALRSAADEDSALRIVHVAALAGQGS-SSAQSLL
MSMEG_0408|M.smegmatis_MC2_155      ---------ADEAQLVDTLRAASAG--ELYVVHIAAGDGAAA--PMRDLL
Mvan_1003|M.vanbaalenii_PYR-1       ---------ADAAPAEEALRATVSQ-PRPHILYLAALEEPGG-SAAETLG
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MMAR_3099|M.marinum_M               -------NVVHQAEFNRRFIGLGPGHRAVFWVPPYHDFGLISGILSALAG
MAV_3108|M.avium_104                --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        TAYYAFIHLADVQPGQRVLIHAGTGGVGMAAVQLARHLGLEVFATASKGK
TH_4458|M.thermoresistible__bu      --------LLANLESISRDAGQGDEARVVSWLPLHHDMGLIGGIFGVVHF
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          RMQHRVLGGTRRLFGAAVAAQLRSP------------------------M
MAB_0939|M.abscessus_ATCC_1997      RIQHQVLGGTRRLFRAAAAAELRAP------------------------I
MSMEG_0408|M.smegmatis_MC2_155      RVQHRTLGGLRRLFRAANDAELRSP------------------------I
Mvan_1003|M.vanbaalenii_PYR-1       WMQHRVLAAARRLFQLAATAGARAP------------------------I
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MMAR_3099|M.marinum_M               NFDLTMMSPMSFIQRPALWFEVMDRVRATVT-------------------
MAV_3108|M.avium_104                --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        WDTLRAMGFDDDHISDSRSLEFEDKFRAATGGRGFDVVLDSLAGEFVDAS
TH_4458|M.thermoresistible__bu      GGTAYLMPPSSFIQRPMSWLEAISWHG---------------------AN
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          WLVTRGAQHVTDTDVVAPDQTCLWGFGRAASLEHPQIWGGLADLGGGTSD
MAB_0939|M.abscessus_ATCC_1997      WIVTRGAQHVIEGDTVAPEQSALWGFGRAAALELPQVWGGLADLSDAGTD
MSMEG_0408|M.smegmatis_MC2_155      WLVTRDGQRVTDTDTVVPEQSCLWGFGRAAALELPHIWGGLADLSGADT-
Mvan_1003|M.vanbaalenii_PYR-1       WLITAGAQRITGDETVEPAQTSLWGFGRAAALEQPELWGGLADVTTGDAE
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MMAR_3099|M.marinum_M               --VAPNFGFELAMRKTTAEQRAGWDLSPLQVIVSAAEPVREDTTRRFFEA
MAV_3108|M.avium_104                --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        LRLVAPGGVFLEMGKTDIRDPGVIAQQYPGVRYRAFDLFEPGRPRMHQYM
TH_4458|M.thermoresistible__bu      ISVGPNFGYQLCVERSTPEERATLDLSTWVRAYCGAEPVRAATMRRFTEA
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          EWSRLLNRIAATHDPAVMEDQVAVRGSTSYVPRLVHRDT----LPSGKPL
MAB_0939|M.abscessus_ATCC_1997      EWAQFIGRVSVSGEASTREDQLALRGQAVHVPRLVRREE----LPSGKPL
MSMEG_0408|M.smegmatis_MC2_155      EWPRLIARITSPRDG---EDQIALRGDAVYAPRLVRRTG----EPSDTPL
Mvan_1003|M.vanbaalenii_PYR-1       EWSALIDHIVAAPTS---EDQIAVRGREIHVARLTRCAE----KANAAAL
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MMAR_3099|M.marinum_M               FAASGIRREAFCPCYGLAEHTVGITVSGRSSLRVDRSQL----EARQLAV
MAV_3108|M.avium_104                --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        LELATLFGDGVLRPLPVTTFDVRRAPAALRYLSQARHTG----KVVMLMP
TH_4458|M.thermoresistible__bu      FAPAGFRADAFHPVYGLAEATLFVSGRPENVLPTVRSLDNAALREHRVVP
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          HLRADATYLVTGGLGSLGLEIAGYLAA-NGAGHLVLTSRRTPDEAAASRI
MAB_0939|M.abscessus_ATCC_1997      EVRSDATYLVTGGLGSIGLEIAGYLAG-RGAKHLVLTSRREPGEAARQRI
MSMEG_0408|M.smegmatis_MC2_155      PVREDRTYLVTGGLGAIGLEVAGYLAS-HGAGHVVLTSRREPGDDARRRL
Mvan_1003|M.vanbaalenii_PYR-1       ELRREATYLVTGGLGALGLEVAEFLAS-HGAGHLVLTGRRSASDTVRQRI
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MMAR_3099|M.marinum_M               PSDAPDAQVLMG-CGQPTDDVDVRIVDPELCVPLGDGQVGEIWADSPSKA
MAV_3108|M.avium_104                --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        GSWAAGTVLITGGTGMAGSAVARHVVARHGVRNLVLVSRRGPDAPGAAEL
TH_4458|M.thermoresistible__bu      AAADDANAAAVVGCGPAAYGEEIVIVDPATRREFPPDVVGEIWVAGENVA
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          EALRERHGCEVRVVTADVADAHAVARLLATVQAEMPPLAGIVHAAGEIGT
MAB_0939|M.abscessus_ATCC_1997      DALAA-QGCEVRAVTADVADGHDVARLLAGIQAELPPLAGIVHAAGEIGT
MSMEG_0408|M.smegmatis_MC2_155      DGLREQYACDVRVITADVADAHDVARLMTTVAAELPPLAGIVHAAGEIGT
Mvan_1003|M.vanbaalenii_PYR-1       DAMRERFDCQVLVATADVADRDDVARLFSTMRSELPPLAGIVHAAGEIGT
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MMAR_3099|M.marinum_M               AGYWGLSAKSRATFQAALAGVEGGRGYLRTGDLGFL-HDGELYVCGRIKD
MAV_3108|M.avium_104                --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        VAELAAAGAQVQVVACDAADRAALAKVIADIPVQHP-LSGVIHTAGALDD
TH_4458|M.thermoresistible__bu      QGYLGKPSESAETFAAHLADSGRGPFLRTG-------DYGFLLDGELFVT
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          TPLADLDDAEVDRVFAGKVWGAWHLSEATSDLQ--LDFFISTSSIASVWG
MAB_0939|M.abscessus_ATCC_1997      TPLSDLEDAEVDRVFAGKVWGAWHLSEAAAGLK--LDFFINTSSIAAVWG
MSMEG_0408|M.smegmatis_MC2_155      TPLSGLDDAEVDRVFAGKVWGAWHLSEALTDLRTDLDFFVSTSSIASVWG
Mvan_1003|M.vanbaalenii_PYR-1       SPLRTLDDAEMDRVFAGKVWGAVYLCEEVADMG--LDFFLATSSIASVWG
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MMAR_3099|M.marinum_M               LLILAGR----NIYPQDIEDSLRDCHPAIRPGG--FAAFAVVDGNSETLA
MAV_3108|M.avium_104                --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        AVVMSLTPDRVDVVLRSKVDAAWHLHELTRDLD--VSAFVMFSSMAGLVG
TH_4458|M.thermoresistible__bu      GRLKDLIIIRGRNYHPNDIEATVQEVHPALMSGRGAAFAVSPDPSGTEQL
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          GFGQAAYGAANAFLDGLAWRLREQGVAGVSVNFGPWSAGMADAQSRARLE
MAB_0939|M.abscessus_ATCC_1997      GYGQTAYSAANAFLDGLAWRLREQGIAGTSVNFGPWSAGMADAESRARLE
MSMEG_0408|M.smegmatis_MC2_155      GFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPWAAGMADAESRARLE
Mvan_1003|M.vanbaalenii_PYR-1       SHGQTAYGAANAFLDGLADSLRARGIPGISVNFGPWAAGMADAKAREQLS
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MMAR_3099|M.marinum_M               VLVEVRTDGSPDLLAGVVAAIRAAVLKDHQLRCGVVVLGPPGSVSKTTSG
MAV_3108|M.avium_104                --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        SSGQANYAAANSFLDALAAHRRAHGLPAISLGWGLWDQASAMTGGLDAAD
TH_4458|M.thermoresistible__bu      VIVQEVDRGRLGEVDTDELIAAIRTAVTSQHDIGVHTVVLVDPLRIPTTS
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          QRGIKTLSPADALAGLSDAVISAAP---HPVVARVDWSRFLPLYQQAGRR
MAB_0939|M.abscessus_ATCC_1997      QRGIKTLSPTDALAGLADVVAASGSNAVQGVIARIDWARFLPLYQQAGKR
MSMEG_0408|M.smegmatis_MC2_155      QRGVRTLSPAEALAGMADVVAGPVQ----GVVAKIDWSRFLPLYQQAGRR
Mvan_1003|M.vanbaalenii_PYR-1       RRGVKTLAPADALAGMADVIAASTA---HAVVARIDWATFLPVYQLQRRR
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MMAR_3099|M.marinum_M               KVQRSRC-------------------------------------RARFLD
MAV_3108|M.avium_104                --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        LARLGREGVLALSTAEALELFDTAMIVDEPFLAPARIDLTALRAHAVAVP
TH_4458|M.thermoresistible__bu      SGKIRRRTCRQRFLDGELDAFAEWR--------------------LATPR
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          GFLAELERELPAAPAQQGPAVTASGRTPLVERLTTAPLQQRKRLLTDYLR
MAB_0939|M.abscessus_ATCC_1997      GFLAELDREVPSHLA--GVAGAQSGSTQLVERLANAPVQQRKKLLTDYLR
MSMEG_0408|M.smegmatis_MC2_155      AFLSELESELPAAATGAAAPATVPGKPPLVEQLTKAPVQQRKSLITNYLR
Mvan_1003|M.vanbaalenii_PYR-1       AFLSQLEREVPDVPD--ASAPAPSGTTRFVEELTLAPVEQRRKLVLEYLR
Mb2971c|M.bovis_AF2122/97           ---------MIEEQRTMSVEGADQQSEKLFHYLKKVAVELD---------
MLBr_00135|M.leprae_Br4923          --------------MTASVEGADQKSEKLISYLKKVVVELD---------
MUL_2005|M.ulcerans_Agy99           --------------MTTSGESADQQNDKLFRYLKKVAVELD---------
MMAR_3099|M.marinum_M               GTLQAQA-LLVDRRTDDEPVGAAPTTEQLLSVVCGQAAEVLGIGAASVDI
MAV_3108|M.avium_104                ----------------------MPGTEQHLDYLKRLTADLR---------
Rv2048c|M.tuberculosis_H37Rv        PMFSDLA-SAPTRRQVDDSVAAAKSKSALAHRLHGLPEAEQHAVLLGLVR
TH_4458|M.thermoresistible__bu      PAQPVPAADEQADEQAGAGPGAGPGADEIRAWFVAQLAGELGLSPDDIDT
                                                                    .                 

Mflv_0405|M.gilvum_PYR-GCK          DAVAEVTRVDAAEIREDAGFFDLGMDSLMAVELRRRIETGVGKEIPVTLV
MAB_0939|M.abscessus_ATCC_1997      DAVAEVTRVDVSEIREDAGFFDLGMDSLMAVELRRRMEQGVGKEIPVTLV
MSMEG_0408|M.smegmatis_MC2_155      NAVAEVTRVDADEIRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLV
Mvan_1003|M.vanbaalenii_PYR-1       AAVAEVTRVDAAEIRDEAGFFDLGMDSLMAIELRRRLEQGLGKELPVTLA
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MMAR_3099|M.marinum_M               DRSLGDQGLNSIGVTELASRLTQVLGQDVQPVDIFNHPTVGDLVQILSPG
MAV_3108|M.avium_104                --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        LHIATVLGNITPEAIDPDKAFQDLGFDSLTAVEMRNRLKSATG---LSLS
TH_4458|M.thermoresistible__bu      GQPFAYYGLDSVRAIQLMTALEAWSGIKVAPTLAYDHPTIDLAAEHLAGL
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          MDHPRLSDAADYLLGDVLGLTEAAT-APKAATVVSTAADEPIAIVAVSCR
MAB_0939|M.abscessus_ATCC_1997      MDHPRISDVADYLLGDVLGLAEQAKPAAQLASAVTGRTDEPIAIVAVSCR
MSMEG_0408|M.smegmatis_MC2_155      MDHPRLSDAADYLLVEVLGLGEQTN--VRQASTVTARTDDPIAVVAVSCR
Mvan_1003|M.vanbaalenii_PYR-1       MDHPHLSDAAEYVLGDVLGLSEHTV--AQPDTPSTVRTDDPIAIVGMACR
Mb2971c|M.bovis_AF2122/97           -------ETRARLREYEQR------------------ATEPVAVVGIGCR
MLBr_00135|M.leprae_Br4923          -------ETRARLREYEQR------------------ATEPVAVVGIGCR
MUL_2005|M.ulcerans_Agy99           -------EARARLREYEQR------------------ATEPVAVVGIGCR
MMAR_3099|M.marinum_M               EKTRHQRGVRERLGHHAASGAG-----------AVALPADPVAIVGIGCR
MAV_3108|M.avium_104                -------RTRRRVAELEGR------------------LSEPVAVVGMACR
Rv2048c|M.tuberculosis_H37Rv        PTLIFDYPTPNRLASYIRTELAGLPQEIKHTPAVRTTSEDPIAIVGMACR
TH_4458|M.thermoresistible__bu      THTATSTAADAGVSTGAGRRPEHGP--------APDRADEPIAIIGIGCR
                                            .   :                          :*:*::.:.**

Mflv_0405|M.gilvum_PYR-GCK          FPG-APNPEAFWDLLSGGVDAIREVPEDR-FDIDEFYDPDPDAAGKTYTR
MAB_0939|M.abscessus_ATCC_1997      FPG-APDPEAFWDVLSGGVDAIREVPEDR-FDIDEFYDPDPEVAGKTYTR
MSMEG_0408|M.smegmatis_MC2_155      FPG-APDPESFWELLAGGVDAIREVPEDR-WDIDEFYDPDPDTPGKTYTR
Mvan_1003|M.vanbaalenii_PYR-1       FPG-ADDTDAFWSVLAEGADLIREIPDDR-FDINEFYDPDPEAAGKIYSR
Mb2971c|M.bovis_AF2122/97           FPGGVDGPDGLWDVVSAGRDVVSEFPTDRGWDVEGLYDPDPDAEGKTYTR
MLBr_00135|M.leprae_Br4923          FPGGVDSPDRLWDVVSECRDVVSEFPTDRGWDVDGLFDPDPDAEGKTYTR
MUL_2005|M.ulcerans_Agy99           FPGGADGPEGLWDLVSQGRDAVTEFPNDRGWDTEGLFDPDPDAEGKTYTR
MMAR_3099|M.marinum_M               FPGGVDSADSLWDMVVSARDVISDFPGDRGWDAGRLFDPDPDALGKTYCA
MAV_3108|M.avium_104                YAGGVDSPEALWDLVIEGRDTVSDFPVDRGWDVEGLYDPDPDAKGKMYTR
Rv2048c|M.tuberculosis_H37Rv        YPGGVNSPDDMWDMLIQGRDVLSEFPADRGWDLAGLYNPDPDAAGACYTR
TH_4458|M.thermoresistible__bu      FPG-ADGPAAYWRLLREGRDAITATPPER-WDTDSVGDG---------TR
                                    :.* . ..   * ::    * :   * :* :*   . :            

Mflv_0405|M.gilvum_PYR-GCK          YGGFLDHIDEFDPEFFGLSPREAVWIEPQQRLMLETVWEGLERAGYAPSA
MAB_0939|M.abscessus_ATCC_1997      FGGFLDGIDGFDPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYSPAA
MSMEG_0408|M.smegmatis_MC2_155      FGGFLDGIDGFDPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYAPSD
Mvan_1003|M.vanbaalenii_PYR-1       YGGFLDGVDGFDPEFFGISPREAVWIDPQQRLVLETAWEGLERAGYSAAA
Mb2971c|M.bovis_AF2122/97           WGAFLDDATGFDAGFFGIAPSEVLAMDPQQRLMLEVSWEALEHAGIDPLS
MLBr_00135|M.leprae_Br4923          WGAFLDDAAGFDAGFFGIAPSEVLAMDPQQRLMLEVSWEALEYAGIDPLS
MUL_2005|M.ulcerans_Agy99           WGAFVENATNFDAGFFGIPPSEVLAMDPQQRLMLEVSWEALEHAGIDPMS
MMAR_3099|M.marinum_M               VGGFLEDAAGFDAGFFGIAPREALAMDPQQRVLLEVSWEALEDAGIDPKA
MAV_3108|M.avium_104                QGSFLQHAGDFDAGFFGIGPSEALAMDPQQRIMLEICWEALERAGIDPSA
Rv2048c|M.tuberculosis_H37Rv        TGGFVDGVGDFDPAFFGVGPSEALAMDPQHRMLLELSWEALERAGIDPTG
TH_4458|M.thermoresistible__bu      WGGFLERIDGFDAGFFGISPREAVRIDPQQRLLLEVAWEALEDAGLVPDR
                                     *.*::    **. ***: * *.: ::**:*::**  **.** **  .  

Mflv_0405|M.gilvum_PYR-GCK          LRGSRTGVFVGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFAL
MAB_0939|M.abscessus_ATCC_1997      LRGSRTGIFAGVGANEYAHLLSSESIDKIEPYFITGNALNAISGRVAFAL
MSMEG_0408|M.smegmatis_MC2_155      LRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFAL
Mvan_1003|M.vanbaalenii_PYR-1       LRGSRSGVYVGVGANEYSHLLSGGSLDGIEAQFITGNALNVIAGRVSFTL
Mb2971c|M.bovis_AF2122/97           LRGSATGVYTGIFAASYGNRDT----GGLQGYGLTGTSISVASGRVSYVL
MLBr_00135|M.leprae_Br4923          LRGSATGVFTGIFAPSYGSRDT----GGLQGYGLTGTAVSVASGRVSYVL
MUL_2005|M.ulcerans_Agy99           LRGSSTGVFTGIFAPSYGGKDV----GALQGYGLTGSPVSVASGRVAYVL
MMAR_3099|M.marinum_M               LRGSATGVFVGTWAQPYGDGGS----DSADGYAMTGTATSVASGRVAYVL
MAV_3108|M.avium_104                LRGTATGVFAGVIHAGYGGEVK----GELEGYGLTGSTLSVTSGRVSYVL
Rv2048c|M.tuberculosis_H37Rv        LRGSATGVFAGVMTQGYGMFAA----EPVEGFRLTGQLSSVASGRVAYVL
TH_4458|M.thermoresistible__bu      LAGSRTGVFTGVSTYDYLHLQLSHP-ELIDAYSGTGTASSIAANRLSYVF
                                    * *: :*::.*     *            :    **   .  :.*:::.:

Mflv_0405|M.gilvum_PYR-GCK          GLEGPAVAVDTACSSSLVAVHQATQALRSGDCDMALAGGVNVLLSPVTVV
MAB_0939|M.abscessus_ATCC_1997      GFEGPAVAVDTACSSALVAVHQAVQALHSGDCDLALAGGVNVLLSPVTVI
MSMEG_0408|M.smegmatis_MC2_155      GFEGPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVV
Mvan_1003|M.vanbaalenii_PYR-1       GLEGPAVAVDTACSSSLVAVHQACQGLQSGDCDLALAGGVNVLLSPATTI
Mb2971c|M.bovis_AF2122/97           GLQGPAVSVDTACSSSLVAIHWAMSSLRSGECDLALAGGVTVMGLPSIFV
MLBr_00135|M.leprae_Br4923          GLEGPAVSVDTACSSSLVAIHWAMSSLRSGECDLALAGGVTVMGLPSIFV
MUL_2005|M.ulcerans_Agy99           GLEGPALSVDTACSSSLVAIHWAMASLRSGECDMALAGGVTVMGLPSIFV
MMAR_3099|M.marinum_M               GLEGPAVSVDTACSSSLVAVHQAVQSLRLGECDLALAGGVTVMATPSVFV
MAV_3108|M.avium_104                GLEGPAVSVDTACSSSLVAMHLAAQSLRSGECDLALAGGVTVMATPAAFV
Rv2048c|M.tuberculosis_H37Rv        GLEGPAVSVDTACSSSLVALHMAVGSLRSGECDLALAGGVTVNATPDIFV
TH_4458|M.thermoresistible__bu      DFRGPSLTLDSACSSSLVAVHQACRSLRDGECDLALAGGVNIMLSAGIGL
                                    .:.**::::*:****:***:* *  .*: *:**:******.:   .   :

Mflv_0405|M.gilvum_PYR-GCK          AASRARMLSPVGRCKTFDASADGYVRSEGCGILVLKRLSDAVRDGDRVCA
MAB_0939|M.abscessus_ATCC_1997      AASRARMLSPVGRCKTFDASADGYVRSEGCGILVLKRLSDAERDGDRVLA
MSMEG_0408|M.smegmatis_MC2_155      AASRARMLSPVGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCA
Mvan_1003|M.vanbaalenii_PYR-1       ATSRARMLSPDGRCKTFDAAADGYVRGEGCGILVLKRLSDAVRDGDRIQA
Mb2971c|M.bovis_AF2122/97           GFSRQRGLAADGRCKAFAAAADGTGWGEGAGVVVLERLSDARRLGHSVLA
MLBr_00135|M.leprae_Br4923          GFSRQRGLAADGRCKAFARAADGTGWGEGAGVVVLERLSDAQRLGHTVLA
MUL_2005|M.ulcerans_Agy99           GFSRQRGLAADGRCKAFAAAADGTGWGEGAGVLVLERLSDAQRNGHNVLA
MMAR_3099|M.marinum_M               GFSRQRGLAPDGRCKAFAEAADGVGWGEGAGVLVLQRLSDARRQGRVVLG
MAV_3108|M.avium_104                EFSRQRALAPDGRCKVYAGAADGTSWSEGAGVLVLERLADARRLGHPVWA
Rv2048c|M.tuberculosis_H37Rv        EFSRWRGLSPDGRCKAFAAAADGTGFSEGGGMLVLQRLSDARRLGHPVLA
TH_4458|M.thermoresistible__bu      NFTRAGVMATDGRCKTFDARADGWVRGEGAGIVVLKPLREALADEDPIYA
                                      :*   ::. ****.:   ***   .** *::**: * :*      : .

Mflv_0405|M.gilvum_PYR-GCK          VIAGSAVNQDGASSGLTVPNGGAQQRLIGTVLARAGITGGEVDYLEAHGT
MAB_0939|M.abscessus_ATCC_1997      VIPGSAVNQDGASSGLTVPNGGAQQRLIGSVLARAGLVGGDVDYLEAHGT
MSMEG_0408|M.smegmatis_MC2_155      VIPASSVNQDGASSGLTVPNGGAQQRLIEATLARAGLSGADVDYLEAHGT
Mvan_1003|M.vanbaalenii_PYR-1       VIRGSAVNQDGASGGLTVPNGGAQQRVIAAALTRAGLSGSDIDYLEAHGT
Mb2971c|M.bovis_AF2122/97           VVRGSAVNQDGASNGLTAPNGLAQQRVIQAALANAGLSAADVDVVEAHGT
MLBr_00135|M.leprae_Br4923          VVRGSAVNQDGASNGLTAPNGLAQQRVIQAALTNAGLSSADVDVVEAHGT
MUL_2005|M.ulcerans_Agy99           VVRGSAINQDGASNGLTAPNGLTQQRVIQAALANCGLTSADVDVVEAHGT
MMAR_3099|M.marinum_M               VVRGSAVNQDGASHGLTAPNGPAQQRVIRAALAGAGLGPADVDVVEAHGT
MAV_3108|M.avium_104                VLRGSAVNQDGASNGLTAPNGPSQQRVIRAALANAGLSAVDVDVVEGHGT
Rv2048c|M.tuberculosis_H37Rv        VVVGSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGT
TH_4458|M.thermoresistible__bu      VIRGSAVNQDGRTNGLMAPSRTAQEVVLTDAYRRAGVSPGVVQYVEAQGI
                                    *: .*::**** : ** .*.  :*: ::  .   .*:    :: :*.:* 

Mflv_0405|M.gilvum_PYR-GCK          GTPLGDPIEVQAAAAAYAGAR-DADRPLLMGSVKTNIGHTESASGAAGLI
MAB_0939|M.abscessus_ATCC_1997      GTPLGDPIEVQAAAAAYGGSR-DADRPLLMGSVKSNIGHTESASGAAGLI
MSMEG_0408|M.smegmatis_MC2_155      GTPLGDPIEVQAAAAAYGAGR-DADRPLLMGSVKTNIGHTESASGAAGLI
Mvan_1003|M.vanbaalenii_PYR-1       GTSLGDPIEVQAAGAVLGAGR-DPDRPLLMGSVKTNVGHLESASGVAGLI
Mb2971c|M.bovis_AF2122/97           ATTLGDPIEAQALLSTYGQGR-PAEQPLWVGSIKSNMGHTQAAAGVAGVI
MLBr_00135|M.leprae_Br4923          ATTLGDPIEAQALLATYGQGR-PADQPLWVGSIKSNMGHTQAAAGVAGVI
MUL_2005|M.ulcerans_Agy99           ATTLGDPIEAEALLATYGQGR-PTDQPLWVGSIKSNMGHTQAAAGVAGVI
MMAR_3099|M.marinum_M               GTRLGDPIEAQALLAVYGQDR-EPGRPLWVGSIKSNMGHAQAAAGVAGVI
MAV_3108|M.avium_104                GTVLGDPIEAQALLATYGQDR-PADRPLWLGSIKSNIGHTSAAAGVAGVI
Rv2048c|M.tuberculosis_H37Rv        GTTLGDPIEAQALLATYGQDRGEPGEPLWLGSVKSNMGHTQAAAGVAGVI
TH_4458|M.thermoresistible__bu      GTPVGDAIEVGALGTVLAEDR-PPDSPCLIGSVKTNIGHLEAAAGIAGLI
                                    .* :**.**. *  :. .  *  .  *  :**:*:*:** .:*:* **:*

Mflv_0405|M.gilvum_PYR-GCK          KVVLSLQHETLPQSLHFDTPSPHIPWDSLPVRVVDTAMPWQ-PNGRPRRA
MAB_0939|M.abscessus_ATCC_1997      KVVLSLQNGVLPQSLHFDNPSPHIPWESLPVRVVDKAIPWQ-ANGRPRRA
MSMEG_0408|M.smegmatis_MC2_155      KVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQ-TNGRVRRA
Mvan_1003|M.vanbaalenii_PYR-1       KVVLSLQHEMLPRHLHFKTPSPHIPWDRLAVRVVAEPTPWR-ADGRPRRA
Mb2971c|M.bovis_AF2122/97           KMVQAMRHGVMPATLHVDEPSPRVDWTSGAVSVLTEAREWS-VDGRPRRA
MLBr_00135|M.leprae_Br4923          KMVQAMRHHVMPATLHVDEPSPRVDWTTGAVSVLTEARDWS-VEGRPRRA
MUL_2005|M.ulcerans_Agy99           KMVQAMRHGLMPASLHVDEPSKRVDWESGAVSVLAEARDWP-DAGRPRRA
MMAR_3099|M.marinum_M               KMVQAMRHGLLPETLHVDEPSGQVDWSAGAVEVLSRARSWLGVPGRPRRA
MAV_3108|M.avium_104                KMVQALRHGVMPKTMHVDVPSPHVDWSAGAVSLLTDPRPWP-EHGGPRRA
Rv2048c|M.tuberculosis_H37Rv        KMVLAMRHELLPATLHVDVPSPHVDWSAGAVELLTAPRVWP-AGARTRRA
TH_4458|M.thermoresistible__bu      KVALALRHRMIPPTLNFTEPNPTIEFDKLPVRVAQTLTPWP-DDSGRAVA
                                    *:. ::::  :*  ::.  *.  : :   .* :      *    .    *

Mflv_0405|M.gilvum_PYR-GCK          GVSSFGFTGTNAHVLIEEAPTDLAGPTEPTAPAEPVDEDAAADPAPAPVE
MAB_0939|M.abscessus_ATCC_1997      GVSSFGFTGTNAHVLIEEAPQPQATP----------DEDDASTPQSAPVS
MSMEG_0408|M.smegmatis_MC2_155      GVSSFGFTGTNAHVLVEEAPPQLHTADAAP----VEPAATAEAGTDDSPQ
Mvan_1003|M.vanbaalenii_PYR-1       GVSSFGFSGTNAHVVLEEPPAQSADLRQPPTDGKDGAAGLESATAPEPAG
Mb2971c|M.bovis_AF2122/97           AVSSFGISGTNAHLILEEAPVPAPAEAPVEASE------STGGP-RPSMV
MLBr_00135|M.leprae_Br4923          GVSSFGISGTNAHVILEEAPT------PVEASY------STADQQRLSVV
MUL_2005|M.ulcerans_Agy99           GVSSFGISGTNAHVILEEAPAP----EAVPDSE------SNKGEPSLPVV
MMAR_3099|M.marinum_M               GVSSFGISGTNAHVIVEQALPEVAESGGVSGVCGQ-GVGSVESVVRASVV
MAV_3108|M.avium_104                GVSSFGISGTNAHVIVEQAPAA----AETEAAP-------ASSTMPDAVV
Rv2048c|M.tuberculosis_H37Rv        GVSSFGISGTNAHVIIEAVPVVP----------------RREAGWAGPVV
TH_4458|M.thermoresistible__bu      GVSAFGFGGTNAHVVLAEAPQVR-------------AAATADDHADGFVE
                                    .**:**: *****:::                                  

Mflv_0405|M.gilvum_PYR-GCK          VLPLSARSPEALVALAQRYETWLTAHPEADLADVCRTAGTGRSHFEHRAA
MAB_0939|M.abscessus_ATCC_1997      VLPLSARSPEALAAVAQRYESWLAAHPDVDLEDVCLTAGRGRSHFEHRAA
MSMEG_0408|M.smegmatis_MC2_155      VLALSARSPEALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAA
Mvan_1003|M.vanbaalenii_PYR-1       VLPISARSPEALTALARRYESWLTAHPDADIADVCYTAGAGRSHFEHRAA
Mb2971c|M.bovis_AF2122/97           PWVISARSAEALTAQAGRLMAHVQANPGLDPIDVGCSLAS-RSVFEHRAV
MLBr_00135|M.leprae_Br4923          PWVVSGRSTAALMAQASRLAFYVQADPEVDPVDVGCALAA-RSVFEHRAV
MUL_2005|M.ulcerans_Agy99           PWVISARSAEALTAQAGRLLAHVQADPQSNPVDIGFSLAG-RSAFEHRAV
MMAR_3099|M.marinum_M               PWVLSAQSRQALVAQASRLLGRVGGDDGLDPVDVGLSLAQ-RCVFEHRAV
MAV_3108|M.avium_104                PWVVSARSAEALAGQARRLLDHVTADAQASPLDVGWSLVSTRAVFEHRAV
Rv2048c|M.tuberculosis_H37Rv        PWVVSAKSESALRGQAARLAAYVRGDDGLDVADVGWSLAG-RSVFEHRAV
TH_4458|M.thermoresistible__bu      ILPLSARSQAALDALAERYESALTG--GVPPADLCHTAGARRAHHDHRLA
                                       :*.:*  **   * *    : .       *:  :    *. .::* .

Mflv_0405|M.gilvum_PYR-GCK          LVVDSVESARIALTDLAQNRLRPGVVRG--EHLNHPTTAWMFTGQGSQYP
MAB_0939|M.abscessus_ATCC_1997      LVVDSIQTAREGLLELAQNRLRPGVVRG--EHTNHPTTAWLFTGQGSQYP
MSMEG_0408|M.smegmatis_MC2_155      LVVDSVERAREGLAALAEGRTPAGVVRG--EHVHRPTTAWLFTGQGSQYP
Mvan_1003|M.vanbaalenii_PYR-1       LVVDSVDGARDLLAGLAEDRLGPGAVRG--VCGDPPKTAWLFTGQGSQYP
Mb2971c|M.bovis_AF2122/97           VVGASREQLIAGLAGLAAGEPGAGVAVG--QPGSVGKTVVVFPGQGAQRI
MLBr_00135|M.leprae_Br4923          VVGESREQLIAGLAGLAVGESGAGVAIG--QAAPLGKTVVVFPGQGAQRI
MUL_2005|M.ulcerans_Agy99           VVGADRQQLLTGLATLADGAPGAGVVTG--QAGSVGKTAVVFPGQGSQRI
MMAR_3099|M.marinum_M               VVGRDREALLAGLTGLARGGPGAGVVVG--QAAAVGKTVLVFPGQGAQWT
MAV_3108|M.avium_104                VVGRERGALATGLAGLASGRPGPATVVG--RARSTGKTVLVFPGQGSQTL
Rv2048c|M.tuberculosis_H37Rv        VVGGDRDRLLAGLDELAGDQLGGSVVRG--TATAAGKTVFVFPGQGSQWL
TH_4458|M.thermoresistible__bu      VVGASRAELIGALAAYRRGEPHPGVFTGRSQSGHRSGVVFVFSDEGSQWR
                                    :*  .       *     .    ..  *         .. :*..:*:*  

Mflv_0405|M.gilvum_PYR-GCK          GMARELFDTEPVFADTVTRCADAVADLLPRPLLDVMFAGGREAGVPPTET
MAB_0939|M.abscessus_ATCC_1997      GMARELFDAEPVFAETVTRCAEAVKDIVTRPLLEVMFATDRETGGKAGEA
MSMEG_0408|M.smegmatis_MC2_155      GMARELFDTQPVFAQTVRQCAEAVADMLPRPLLDVLFATDRET----ADL
Mvan_1003|M.vanbaalenii_PYR-1       GMARELFDTEPVFRDTVTRCAEAIGDTLPRPLLEVLFDTDGDN----GQT
Mb2971c|M.bovis_AF2122/97           GMGRELYGELPVFAQAFDAVADELDRHLRLPLRDVIWGADADL-------
MLBr_00135|M.leprae_Br4923          GMGRELCSQLPVFAEEFDAVTGELDRHMRLPLRDVVWGADAGL-------
MUL_2005|M.ulcerans_Agy99           GMARELHDQLPVFAEAFDAVADELDRHLRIPLCEVMWGSDVAL-------
MMAR_3099|M.marinum_M               GMGRGLHGQFPAFARAFDAAVDELDQHLPMPLREVMWGTDKGL-------
MAV_3108|M.avium_104                GMGRQLYERFEVFAGALDEAVAVVDEHSRLSVREVMWGADPEL-------
Rv2048c|M.tuberculosis_H37Rv        GMGMGLHAGYPVFAEAFNTVVGELDRHLLRPLREVMWGHDENL-------
TH_4458|M.thermoresistible__bu      GMAQRLYAEDQVFRTALAECDRALRRHMEISPLSELLADPSHSR------
                                    **.  *     .*   .      :      .  . :              

Mflv_0405|M.gilvum_PYR-GCK          LRHTSFAQPALFAVEMGLARLWQSWGIVPDVVLGHSVGQYAAACVAGVFS
MAB_0939|M.abscessus_ATCC_1997      LRHTSFAQPALFAVEMGLARLWQSWGIEPDVVLGHSVGQYAAACVAGVFS
MSMEG_0408|M.smegmatis_MC2_155      LQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACVAGVFS
Mvan_1003|M.vanbaalenii_PYR-1       LRHTSYAQPALFAIEMGLARLWQARGIEPDVVLGHSVGQYAAACVAGVFG
Mb2971c|M.bovis_AF2122/97           LDSTEFAQPALFAVEVASFAVLRDWGVLPDFVMGHSVGELAAAHAAGVLT
MLBr_00135|M.leprae_Br4923          LDSTEFAQPALFAVEVALFAVLQHWGLQPDFVMGHSIGELAAAYVAGVLA
MUL_2005|M.ulcerans_Agy99           LDSTEFAQAALFAVEVALFAALQRWGLQPDFVMGHSVGELSAAYVAGVLT
MMAR_3099|M.marinum_M               LDSTEFAQPALFALEVGLWALLEHWGIRPDFVLGHSVGELSAAHVAGVLS
MAV_3108|M.avium_104                LQSTEFAQPALFVFEVALAALWESLGVTPDVVMGHSVGEIAAACVAGVLS
Rv2048c|M.tuberculosis_H37Rv        LNSTEFAQPALFAVEVALFRLLGSWGVRPDFVMGHSIGELSAAHVAGVLS
TH_4458|M.thermoresistible__bu      MDEVTIASPALFAVQVALAALWQSWGVEPAAVIGHRMGEVAAAHVAGVLG
                                    :  .  *..***..::.        .: *  *:** :*: :** .***: 

Mflv_0405|M.gilvum_PYR-GCK          LEDGARLMAERGRLFGSLPEGGRMVAVFADAKRVEQVAADFP-RVSVGAY
MAB_0939|M.abscessus_ATCC_1997      IEDGARLIAERGRLFGGLPAGGRMVAVFSDAKHVEQIAGEFP-RVSVGAY
MSMEG_0408|M.smegmatis_MC2_155      LDDGARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAGEFP-RVSVGAY
Mvan_1003|M.vanbaalenii_PYR-1       LEDGARLVADRGRLFGGLPVGGRMVAVFTDAEVVEDFADEFP-QVSVAAY
Mb2971c|M.bovis_AF2122/97           LADAAMLVVARGRLMQALPAGGAMVAVAASEDEVEPLLGEG---VGIAAI
MLBr_00135|M.leprae_Br4923          PADAAMLVVARGRLMQSMPAGGTMWAVAASEDEVVSLLGEG---VGIAAI
MUL_2005|M.ulcerans_Agy99           LVDAAMLVVARGRLMQALPAGGAMVAVAAAEDEVLPSLTDG---VGIAAI
MMAR_3099|M.marinum_M               LADAAMLVAARGRLMQGLPAGGVMVALGVGEQEVDPLLAESAHPVSIAAI
MAV_3108|M.avium_104                LRDAARLVAARGALMAALPPGGVMVAVTAGESQVGPLLGGG---VSIAAV
Rv2048c|M.tuberculosis_H37Rv        LENAAVLVAARGRLMQALPAGGAMVAVQAAEEEVRPLLSAE---VDIAAV
TH_4458|M.thermoresistible__bu      LDDAAALLCGRTRLSRLASTG-----------------------------
                                      :.* *:  *  :    . *                             

Mflv_0405|M.gilvum_PYR-GCK          NGP-NTVLSGPGEDLEQIVGTFGEDGIRCTWLETSHAFHSELLDPVLDEF
MAB_0939|M.abscessus_ATCC_1997      NGP-NTVLSGPGEDLEQAVARFQEEGIRCTWLETSHAFHSELLDPILDEF
MSMEG_0408|M.smegmatis_MC2_155      NGP-NTVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDEF
Mvan_1003|M.vanbaalenii_PYR-1       NGP-NTVLAGPASDLEQIVAGCSGEGIRTTWLDTSHAFHSALLDPVLDEF
Mb2971c|M.bovis_AF2122/97           NAPESVVISGAQAAANAIADRFAAQGRRVHQLAVSHAFHSPLMEPMLEEF
MLBr_00135|M.leprae_Br4923          NAPESVVISGPQAAVSAIADKFAAQGRRVHQLAVSHAFHSPLMEPMLEEF
MUL_2005|M.ulcerans_Agy99           NAPKSVVISGAEAAVTAISDQFAQQGRRVHRLAVSHAFHSPLMEPMLEEF
MMAR_3099|M.marinum_M               NAPEQVVISGAQAAVMTIADQLAARGHRVQQLAVSHAFHSPLMEPIVEEF
MAV_3108|M.avium_104                NGPDAVVLSGEQEAVAAVADRLAGSGARVHRLAVSHAFHSALMEPMLDGF
Rv2048c|M.tuberculosis_H37Rv        NGPASLVISGAQNAVAAVADQLRADGRRVHQLAVSHAFHSPLMDPMIDEF
TH_4458|M.thermoresistible__bu      --------------------------------------------AVREGL
                                                                                .: : :

Mflv_0405|M.gilvum_PYR-GCK          ESYAAQLQFAAPTLPLVCNRTGAVLTGQT-SLDAQYWRRHSRQPVQFAES
MAB_0939|M.abscessus_ATCC_1997      ESYAAQVQFAAPTLPLVCNRTGAVLTAQT-PIDGQYWRRHSRQPVQFAES
MSMEG_0408|M.smegmatis_MC2_155      EAYAAQFQFAAPTLPLVCNRTGAVLTGQT-PLDAQYWRRHSRQPVQFAES
Mvan_1003|M.vanbaalenii_PYR-1       ESCAARLAYAAPTRPLVCNRTGAVVTGPG-VIDAQYWRRHARQPVQFAES
Mb2971c|M.bovis_AF2122/97           ARVAARVQAREPQLGLVSNVTGELAGPD--FGSAQYWVDHVRRPVRFADS
MLBr_00135|M.leprae_Br4923          VRVAAQVEVRKPQIGLVSNVTGELAGPD--FGSPQYWGEHVSRAVRFVDS
MUL_2005|M.ulcerans_Agy99           ARIAAQVEAREPQIALVSNVTGELASADGGFGSAQYWVEHVRRAVRFADS
MMAR_3099|M.marinum_M               AEIAGRVTVEAPRIGVISNLTGELAGPG--YGSKAYWREHIRRPVRFSDS
MAV_3108|M.avium_104                AAAAAGIEPRPPRIPLVSNLTGQLAGPG--YGTPQYWVDHVRRPVRFVDG
Rv2048c|M.tuberculosis_H37Rv        AAVAAGIAIGRPTIGVISNVTGQLAGDD--FGSAAYWRRHIRQAVRFADS
TH_4458|M.thermoresistible__bu      DGLLANLRPDDPRIPLYSTVTGDAVTGRG--FGAAHWMENLHSPVRFSAA
                                        . .    *   : .. **             :*  :   .*:*  .

Mflv_0405|M.gilvum_PYR-GCK          VRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHLAAPRAIASLRKGVADRR
MAB_0939|M.abscessus_ATCC_1997      VRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHLAPPRAIVSLRKGVEDRR
MSMEG_0408|M.smegmatis_MC2_155      VRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHMAAPRAVASLRKGVADRR
Mvan_1003|M.vanbaalenii_PYR-1       VRTLADLGCSVLMEIGPQPFLIAAALRVWPESAATPRAIPSLRKGPDARR
Mb2971c|M.bovis_AF2122/97           ARHLQTLGATHFIEAGPGSGLTGSIEQSLAP--AEAMVVSMLGKDRPELA
MLBr_00135|M.leprae_Br4923          ARHLQTLGATHFIESGPSSGLMGAIEQSLAP--AEAVVVSMMGKDRPELA
MUL_2005|M.ulcerans_Agy99           ARQLHTLGVTHFVEVGPGSGLTGSIEQSLAP--AEAVVVSMLGKDRPEVA
MMAR_3099|M.marinum_M               VACARAQGATHFVEAGPGAGLTAAIEQSLGS--VAATVVAVLGKQRPEPD
MAV_3108|M.avium_104                VRLAESQGAGVFLEVGPGAALTSAVEQSLTS--DRAMSVVTMPKGRPEVD
Rv2048c|M.tuberculosis_H37Rv        VRFAQAAGGSRFLEVGPSGGLVASIEESLPD--VAVTTMSALRKDRPEPA
TH_4458|M.thermoresistible__bu      VRRLLGRGHDAFLEISAHPMLLSAVQEDAADLGRSCTTLVSMRRGECGRD
                                    .      *   ::* ..   * .:  .           :  : :      

Mflv_0405|M.gilvum_PYR-GCK          QIADALAAAYIGGHKPDFAALHEQ-RGVRLELPTYPFQRRRFWPK---SA
MAB_0939|M.abscessus_ATCC_1997      QIADALASAYVSGHRPNFAALQRH-PRRTVELPTYPFQRRRFWPK---SS
MSMEG_0408|M.smegmatis_MC2_155      QIADALASAYVGGHRPDFAAVHRQ-PRRPVELPTYPFQRRRFWPK---AS
Mvan_1003|M.vanbaalenii_PYR-1       QLAEAVAAAYIAGHRLDFTGHDGG-PHRRLPLPTYPFQHRSYWPK---TA
Mb2971c|M.bovis_AF2122/97           SALGAAGQVFTTGVPVQWSAVFAGSGGRRVQLPTYAFQRRRFWETPGADG
MLBr_00135|M.leprae_Br4923          SVLGAAGQLFATGMPVEWPAVFAGSSRRRVTLPTYAFQRRRFWETPGTDG
MUL_2005|M.ulcerans_Agy99           SVLTAFGQLFSTGMSVDWPAVFAGSGATRVDLPTYAFQRRRFWEVPGADG
MMAR_3099|M.marinum_M               SLLDAAAQLFASGARLDWPAVFLGWGGRRVSLPTYAFMRQRFWLTPHLAG
MAV_3108|M.avium_104                SLLTAAARLFTAGADVRWSAAFTGLHARRVDLPTYAFARRRFWLSGDAVG
Rv2048c|M.tuberculosis_H37Rv        TLTNAVAQGFVTGMDLDWRAVVG--EAQFVELPTYAFQRRRFWLS-GDGV
TH_4458|M.thermoresistible__bu      VLMTSLAALYASGHAVDWARVHPH-GSHCTAAPTYPWQRQRFWLDIDRCD
                                        : .  :  *    :              ***.: :: :*       

Mflv_0405|M.gilvum_PYR-GCK          GMAIDGRVGASAGSGILGSGKD-LASGDSVYTSRLSVKTQPWLSDHVIYG
MAB_0939|M.abscessus_ATCC_1997      GTAIEG--GGGLPSGILGRGED-LASGDSVYISRLSVRSQPWLSDHVIYG
MSMEG_0408|M.smegmatis_MC2_155      SIAVDG---GTAASGILGSGKD-LASGDTIYTSRLSVKSQPWLADHVIYG
Mvan_1003|M.vanbaalenii_PYR-1       GIRSDG----SSGSGLLGSAQD-LASGDIVHTSRLSVKTQPWLSDHVIYG
Mb2971c|M.bovis_AF2122/97           PADAAGLGLGATEHALLGAVVERPDSDEVVLTGRLSLADQPWLADHVVNG
MLBr_00135|M.leprae_Br4923          TASVSGLGLGSTEHALLGAVVERPDSGGVVLTGRLSLANQPWLADHVIGG
MUL_2005|M.ulcerans_Agy99           PADATGLGLGGAEHALLGAVVERPDSGGVVLTGRLALADQPWLADHVIGG
MMAR_3099|M.marinum_M               SVGAAELGSGNPRHPLLDAVVEHPDSGEVILAGRLSRRAQPWLADHVIGG
MAV_3108|M.avium_104                SANIASLGLAEAEHPLLGAVLDRPDSGGVVLTGRLSTAAQPWLADHAVAG
Rv2048c|M.tuberculosis_H37Rv        AADAAGLGLAASEHALLGAVIDLPASGGVVLTGRLSPSVQGWLADHSVAG
TH_4458|M.thermoresistible__bu      TGDGAGTG------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          TVVVPGATYAAMALAAVGTP--AHAKDVFFYEPIILPEKSSREVQLTVHP
MAB_0939|M.abscessus_ATCC_1997      TVVVPGATYAAMALAAVGTP--ARAKDVFFYEPIILPEKSSREVQLTLHP
MSMEG_0408|M.smegmatis_MC2_155      TVVVPGATYAAMALAAVGTP--ARLKDVFFYEPIILPEKASREVQLTLHP
Mvan_1003|M.vanbaalenii_PYR-1       TVVVPGATYAAMALAAMPTP--ARVQEVFFYEPIILGDKDSREVQLMLHR
Mb2971c|M.bovis_AF2122/97           VVLFPGAGFVELVIRAGDEVGCALIEELVLAAPLVMHPGVGVQVQVVVG-
MLBr_00135|M.leprae_Br4923          VVLFPGAGFVELVIRAGDEVGCAGVEELVLAAPLVLHPGSGVQVQVVVA-
MUL_2005|M.ulcerans_Agy99           VVLFPGAGFVELAIRAGDEVGCAVVEELVLAAPLVLHPGMGVQVQVIVG-
MMAR_3099|M.marinum_M               LVLLPGTGFVELVIRAGDQLGCAAIDELTLTNPLIVPDGSEVQVQVVVG-
MAV_3108|M.avium_104                TVLFPGAGFVELALRAGDEVGCPVVEELTLSAPLSLPAGGTVQLQVVVAD
Rv2048c|M.tuberculosis_H37Rv        VTIFPGAGFVELAIRAGDEVGCGVVDESTLAAPLVLPASGSVAVQVVVN-
TH_4458|M.thermoresistible__bu      ----------------------GTAERTVVPAPLPAPS------------
                                                             .   .  *:                

Mflv_0405|M.gilvum_PYR-GCK          SVDGE-SKFQVHSRPYGERGAEWALNAEGVVASGVGD---SPAAAGDLED
MAB_0939|M.abscessus_ATCC_1997      LEDGSGSKFQVHSRPYGERDVDWSLNAEGTVVTGIGDDAEPAPEAAEPAE
MSMEG_0408|M.smegmatis_MC2_155      ADGGSVLSFQIHSRPYGERGADWSLNAEGTVDTAGSD---PDAAADEQSD
Mvan_1003|M.vanbaalenii_PYR-1       TDDADGWTFEVHSRPYGDRDADWSRNASGTVAAGVGD-----AAPDAAAD
Mb2971c|M.bovis_AF2122/97           AADESGHRAVSVYSRGDQSQG-WLLNAEGMLG---------VAAAETPMD
MLBr_00135|M.leprae_Br4923          AADESSRRAVSVYSRGDQSHGGWLLNAEGLLE---------VDAAEATVD
MUL_2005|M.ulcerans_Agy99           TADDSGNRALSVYSRGDKSED-WLLNAEGMLG---------VEAASSGAD
MMAR_3099|M.marinum_M               AAERSGRRTVSVYSRADHIGAAWVQHAEGALG---------VDPMPASGD
MAV_3108|M.avium_104                AAGQPGSRSVAVYSR--VAQSEWTLHAEGVLS---------EAAPAPAAE
Rv2048c|M.tuberculosis_H37Rv        GPDESGVRGVSVYSRGDVGTG-WVLHAEGALR---------AGSAEPTAD
TH_4458|M.thermoresistible__bu      ------------------------------------------ASAAPTVD
                                                                                     :

Mflv_0405|M.gilvum_PYR-GCK          PVDEAIERLNRMRPQELFETFADLELAWGPTWSGSLKSLWLGEGEAIGDI
MAB_0939|M.abscessus_ATCC_1997      PVDAAIERMERMRPMELFEIFADLELAWGPTWSGSLKSLWLGEGEAIGDV
MSMEG_0408|M.smegmatis_MC2_155      PVDEVIERLERMRPQDLFETFADLELAWGPTWSGSLKSLWLGDGEAVGDI
Mvan_1003|M.vanbaalenii_PYR-1       PVDNAIERLTRTRPQQLFDAFADNDLAWGPAWCSSLRSLWVGTGEAVGDI
Mb2971c|M.bovis_AF2122/97           LSVWPPEGAESVDISDGYAQLAERGYAYGPAFQG-LVAIWRRGSELFAEV
MLBr_00135|M.leprae_Br4923          LSLWPPEGAESVDISDAYPQLAERGYAYGPAFQG-LVAIWRRGSELFAEV
MUL_2005|M.ulcerans_Agy99           LSVWPPEGAESVDISDGYAQLADRGYAYGPGFQG-LVGVWRRDSELFAEV
MMAR_3099|M.marinum_M               FSVWPPSGAEAVRVSDAYERLAQLGYRYGPAFRG-IEAIWRRGTEVYAEV
MAV_3108|M.avium_104                LSVWPPADAEAVDVAGGYDDLAGRGYGYGPAFRG-LRAVWRRGAETFAEV
Rv2048c|M.tuberculosis_H37Rv        LAMWPPAGAVPVEVADGYQQLAERGYGYGPAFRG-LTAMWRRGDEVFAEV
TH_4458|M.thermoresistible__bu      EVLLCADQRERRELLESYLR------------------------------
                                                     :                                

Mflv_0405|M.gilvum_PYR-GCK          LVGAELAEQLGTEPMHPVLMDLCTGVAFPAFPALLAAEQGVNDLYLPLRY
MAB_0939|M.abscessus_ATCC_1997      LVGEELAEQLGTEPMHPVLMDLCTGVAFPAFPALLAAEQGVNDLFLPLRY
MSMEG_0408|M.smegmatis_MC2_155      LVGAELAEQLGSEPMHPVLMDLCTGVAFPAFPALLAAEQGVNDLFLPLRY
Mvan_1003|M.vanbaalenii_PYR-1       AVGAELGEHLGREPIHPVLLDLCTGIAGAALLAAAAQTDADPELFLPLRY
Mb2971c|M.bovis_AF2122/97           VAPGEAGVAVDRMGMHPAVLDAVLHALG---LAVEKTQ-ASTETRLPFCW
MLBr_00135|M.leprae_Br4923          VAP--TGVVVDGMGMHPALLDAVLHALG---LAIENTQ-ATTEMRLPFCW
MUL_2005|M.ulcerans_Agy99           VAP--SGVAVDKMGMHPVVLDAVLHALG---LTAEQNP-DSDETKLPFCW
MMAR_3099|M.marinum_M               AIPADAELGINGYGIHPVLLDAVLQAAA---VAVD-----SGDTRLPYSW
MAV_3108|M.avium_104                ELPEQAGVSTGRFGIHPVLLDAALHALG---VADKR-----LETVLPFSW
Rv2048c|M.tuberculosis_H37Rv        ALPADAGVSVTGFGVHPVLLDAALHAVV---LSAESAERGQGSVLVPFSW
TH_4458|M.thermoresistible__bu      ------DRVAAELGVLPPLLDVAAPLST----------------------
                                                  : * ::*                             

Mflv_0405|M.gilvum_PYR-GCK          GQVSLQEKMPRRFYCRATWHEAPLDSETQVFDLEYLDRDGRHLGGVREFT
MAB_0939|M.abscessus_ATCC_1997      GQVTLKEKMPRRFYCRARWHESPLDSETQVFDLDYLDRDGRHLGGIREFT
MSMEG_0408|M.smegmatis_MC2_155      GQVTLAEKMPRRFYCRARWHRSALDSETQVFELEFVDLGGRALGGIREFT
Mvan_1003|M.vanbaalenii_PYR-1       GRVEVRERMPRRFYCRARWQTGGIDSETQVFDLDFLDHDGRNLGGIREFT
Mb2971c|M.bovis_AF2122/97           RGVSLHAGGAGRVRARFASAG------ADAISVDVCDATGLPVLTVRSLV
MLBr_00135|M.leprae_Br4923          RGVSLHAGGAGRVRARFTSAG------ADAIAVDIADSAGLPVLTVRSLV
MUL_2005|M.ulcerans_Agy99           RGVSLHAGGAGRVRARLTMSG------PDSISVEIADAAGLPVLTVGALV
MMAR_3099|M.marinum_M               RGISLHAAAAKRIRARIAPVG------EVGYAVECADVAGLPVLTMGSLV
MAV_3108|M.avium_104                QGVSLHAAGASRVRVRLAPAG------AGAVSVELADASGVPVLSVRELV
Rv2048c|M.tuberculosis_H37Rv        QGVSLHAAGASAVRARIAPVG------PSAVSIELADGLGLPVLSVASML
TH_4458|M.thermoresistible__bu      ------------------------------------------------LG
                                                                                    : 

Mflv_0405|M.gilvum_PYR-GCK          VKRAPREALLRGLGGDAT----RLLYTLGWHEVPVP----ESGDGAAPQG
MAB_0939|M.abscessus_ATCC_1997      VKRAPREALLRGLGGDAT----RLLYTLGWHEVAVPPVAGEGEESAASIG
MSMEG_0408|M.smegmatis_MC2_155      VKRAPREALLRGLGGDAT----RLLYTLGWHEVPPP------PSADDAVG
Mvan_1003|M.vanbaalenii_PYR-1       VKRAPREALLRGLGADAT----RLIYRVGWRETSPP---VRDDGALGPSS
Mb2971c|M.bovis_AF2122/97           TRPITAEQLRAAVTAAGG-ASDQGPLEVVWSPISVV------SGGANGSA
MLBr_00135|M.leprae_Br4923          TRAMTAEQLRTAVTAAGG-ALEQGPMDLVWSPIPLS------SDGHGG-G
MUL_2005|M.ulcerans_Agy99           TRAMSAAQLRAAVAEAGGGAPDQGPLDVIWSPIPLS------GSGTNGSA
MMAR_3099|M.marinum_M               TRPVSAEQLHAGAATAIG-RPAQGLLELAWSPISPA------HGALDGGG
MAV_3108|M.avium_104                TRAVSAEQLAAAVAVRSG---SGELLDVAWSVIEPR------NSLPDNPI
Rv2048c|M.tuberculosis_H37Rv        ARPVTDQQLRAAVSSSGP----DRLFEVTWSPQP-----------SAAVE
TH_4458|M.thermoresistible__bu      IDSLTAAELRARVERDLG--------------------------------
                                        .   *                                         

Mflv_0405|M.gilvum_PYR-GCK          TWLIGGFDELAVSVPGCIPADR----------------TNPESLRQLLTD
MAB_0939|M.abscessus_ATCC_1997      TWLIAGFDELAAKVPGCIPLNRE---------------TDPELLGEVLVA
MSMEG_0408|M.smegmatis_MC2_155      TWLIAGFDELAAKVPGCVPIDRN---------------TDLQVLGEVLSQ
Mvan_1003|M.vanbaalenii_PYR-1       TWLVAGLDALADDVPGSIRIGFDRIWDPDRDGRVVLDPADDEHWRRLFAL
Mb2971c|M.bovis_AF2122/97           PPAPVSWADFCAGSDG----------------------------------
MLBr_00135|M.leprae_Br4923          LPSVVSWADYCAGRGN----------------------------------
MUL_2005|M.ulcerans_Agy99           QPAVVSWADFCAGGDGGAA---G---------------------------
MMAR_3099|M.marinum_M               HQTVLSWADFTAGAAAAADGVGG---------------------------
MAV_3108|M.avium_104                SEGVTVWEPAAVDGAG----------------------------------
Rv2048c|M.tuberculosis_H37Rv        PLPVCAWGTTEDSAAV----------------------------------
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          AHGRGLPFSGVVWRAARSDGDES--DAEVAARLEAEIAELLGAVHTVQ--
MAB_0939|M.abscessus_ATCC_1997      AKERGVPFSGVVWRAAGPGATES--TTESAARLEGEIAHLLSAVHTVQNS
MSMEG_0408|M.smegmatis_MC2_155      AHARGAGFSGVVWRCATPGRKESGSASAESARLEAEITNLLSAVHAAQ--
Mvan_1003|M.vanbaalenii_PYR-1       ADERRAPVAGVVLGVTGRARPEE-PSADFAARLEAQIRDVLGAVHSLS--
Mb2971c|M.bovis_AF2122/97           -------DASVVVWELESAGGQASS---VVGSVYAATHTALEVLQSWLG-
MLBr_00135|M.leprae_Br4923          -------DTGVVVWEFGSASAGAQAPVDSVAAVYSATHAALQVLQFWFG-
MUL_2005|M.ulcerans_Agy99           -------DAGVVVWEPNPAG------EDVVGPVYAATHAALEVLQSWFD-
MMAR_3099|M.marinum_M               -------RAVAVVWESRTAET------DVVGSVYARIHAALSVLQHWLA-
MAV_3108|M.avium_104                -----------------------------PAAVHAATHQALGVLQSRLA-
Rv2048c|M.tuberculosis_H37Rv        ------------VFESVPLAG------DVVAGVYAATSSVLDVLQSWLT-
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          -GGEVKLPGGLWIVTERAVATESGEPVDPVQAALWGFGRTAINEEPALRC
MAB_0939|M.abscessus_ATCC_1997      AQNGVKLPGGLWIVTERAVATESGEPVDPVQAALWGFGRTTINEEPALRA
MSMEG_0408|M.smegmatis_MC2_155      -GPSVKLPGGLWIVTEHGVACESGEPVDPVQAALWGFGRTTINEEPALHC
Mvan_1003|M.vanbaalenii_PYR-1       -ALGAKPAAGLWIVTERAVAAEAGEPVDPVQSALWGLGRTLIAEEPGLRC
Mb2971c|M.bovis_AF2122/97           ----ADRAATLVVLTHGGVGLAGEDISDLAAAAVWGMARSAQAENP-GRI
MLBr_00135|M.leprae_Br4923          ----QDRAGTLVVLTRGAVGLVGEGISDLAAAAVWGMVRSAQSEHS-GKI
MUL_2005|M.ulcerans_Agy99           ----GDRAGTLVVLTHGAVAMPGENVSDLAGAAVWGIVRSAQAENP-GRI
MMAR_3099|M.marinum_M               ----QDQLASLVVVTHGAVGLPGEAITDLAGSAVWGLARSAQAESP-GRI
MAV_3108|M.avium_104                ----GEAGGVLVVSTRGAVGLPGEDVADLAGAAVWGLVRSAQAEHP-GRV
Rv2048c|M.tuberculosis_H37Rv        ----RDGAGVLVVMTRGAVALPGEDVTDLAGAAVWGLVRSAQTEHP-GRI
TH_4458|M.thermoresistible__bu      ---------IVIPVAQLLNGPSVSDLAEWISTTMVGFGSTTPEPES----
                                              :   :.   .       :   ::: *:  :     .    

Mflv_0405|M.gilvum_PYR-GCK          RLVDCDGSPQAVQALAALLSTP-VDEPELAVRQGKLLASRLLPWSRSGHL
MAB_0939|M.abscessus_ATCC_1997      KLVDGDGSPEAVQALARLLVTP-VDEPEIAVRQGKLLASRLLPWSRTGHL
MSMEG_0408|M.smegmatis_MC2_155      RLVDCDGSSEAVDLLAALLAAPGIQEPEIAVRQGKLLASRLLPWARSGHL
Mvan_1003|M.vanbaalenii_PYR-1       LLVDLDGSEDAGPALARLLGAP-GDEPELALRQGRLLVPRLLPWSRSGQL
Mb2971c|M.bovis_AF2122/97           VLIDTDA----AVDASVLAGVG---EPQLLVRGGTVHAPRLSPAP--ALL
MLBr_00135|M.leprae_Br4923          VLIDTDS----AVDVAVLADLG---ESQLLVRCNTVHAARLSPAP--QLL
MUL_2005|M.ulcerans_Agy99           VLVDADA----AVEAAELVAVG---EPQLVVRSGAAHAARLAPAA--PLL
MMAR_3099|M.marinum_M               VLVDIDTP-N-TPDLGVLLAGR---EPQLVVRGDSVFCARLRPVE--APL
MAV_3108|M.avium_104                VLVDTDG----SLDLATVIGCG---EPQLVVRDGVAYRARLRPAGRRALL
Rv2048c|M.tuberculosis_H37Rv        VLVDSDAP-LDDSALAAVVTTG---EPQVLWRRGEVYTARVHGSRAVGGL
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          TVPRGGD-YVLAPTERGAIDNLRLTDSEVPPPAE--GYVQVRVEAAGLNF
MAB_0939|M.abscessus_ATCC_1997      TVPRGSD-YVLAPTERGAIDNLRITEKEVPAPDE--GYVQVRVEAAGLNF
MSMEG_0408|M.smegmatis_MC2_155      TLPRGGD-FVLAPTERGAIDNLRLTETDVPEPDE--GYVQVRVEAAGLNF
Mvan_1003|M.vanbaalenii_PYR-1       AIPRGTD-YVLAPTERGVLDNLRVSETEVTAPPE--GHVQVRVEAAGLNF
Mb2971c|M.bovis_AF2122/97           ALPAAESAWRLAAGGGGTLEDLVIQPCPEVQAPLQAGQVRVAVAAVGVNF
MLBr_00135|M.leprae_Br4923          ALPVGESMWRLAADGGGTLEDLVIQPCPEVQAPLQAGHMRVAVAAVGVNF
MUL_2005|M.ulcerans_Agy99           AVPADESAWRLAAGGGGTLEDLVIEPCPEVQAPLAAGQVRVAVRAVGVNF
MMAR_3099|M.marinum_M               EVPVGQSAWQLSTGGGGTLADIVVQPCPPAQAPLEPGQVRVAVAAAGVNF
MAV_3108|M.avium_104                ELPGPPAVWRLAAGDAGTLEDLAVQEHP--AAELAPGQVRVRVAAAGVNF
Rv2048c|M.tuberculosis_H37Rv        LVPPSDRPWRLAMSTAGTFENLRLELIPDADAPLGPGQVRVAVSAIAANF
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          RDVLNVLGLYPGDPGPIGGDFAGTVTQLGEGVTGLDVGQRVYGSMQGAFA
MAB_0939|M.abscessus_ATCC_1997      RDVLNVLGLYPGDPGPIGGDFAGIVTQLGEGVTGVEVGQRVYGSMQGAFG
MSMEG_0408|M.smegmatis_MC2_155      RDVLNVLGLYPGDPGPIGGDFAGTVTQLGAGVSGLEIGQRVYGSMQGAFA
Mvan_1003|M.vanbaalenii_PYR-1       RDVLNALGLYPGDPGPIGGELAGVVTAPGPDVDGFDVGQRVFGFAVGAFA
Mb2971c|M.bovis_AF2122/97           RDVVAALGMYPGQAPPLGAEGAGVVLETGPEVTDLAVGDAVMGFLGG-AG
MLBr_00135|M.leprae_Br4923          RDVVAALGMYPGQAPPLGAEGAGVVIEIGPEVTGVAVGDAVMGFLGG-AG
MUL_2005|M.ulcerans_Agy99           RDVVAALGMYPGAAPPLGAEGAGVVLEVGPQVSGVAVGDSVMGFLGG-AG
MMAR_3099|M.marinum_M               RDVLMALGMYPGAQPVLGGEGSGVVLEVGPQVSGVGVGDAVMGLIAG-VG
MAV_3108|M.avium_104                RDVLVALGMYPGAA-QLGAEGAGVVTEVGAGVTDVAVGDAVMGIFGL-VG
Rv2048c|M.tuberculosis_H37Rv        RDVMIALGLYPDPDAVMGVEACGVVIETSLNKGSFAVGDRVMGLFPEGTG
TH_4458|M.thermoresistible__bu      ---------------------AGVPGRSRPPDGAVASGSGDGGRWIELLN
                                                         .*           .  *.   *       

Mflv_0405|M.gilvum_PYR-GCK          SRFNVPGQFLAPIPDGVSAVEAATIPAAALTVRLSF-DWAQVKSGDKVLI
MAB_0939|M.abscessus_ATCC_1997      SRFNVPAQFLAPIPDGISGVEAATIPAAALTVRLSF-DWAQLKPGDKVLI
MSMEG_0408|M.smegmatis_MC2_155      SRFNVPAQFLAPIPDGIGAVEAATIPAAALTVRLAF-DWAQLKPGDKVLI
Mvan_1003|M.vanbaalenii_PYR-1       SRVNVPVQFLAPVPEGISAVAAATTPAAVLTAGLAF-DWAALRAGDRVLI
Mb2971c|M.bovis_AF2122/97           PLAVVDQQLVTRVPQGWSFAQAAAVPVVFLTAWYGLADLAEIKAGESVLI
MLBr_00135|M.leprae_Br4923          PLAVVHQQLITQMPQGWSLAEAAAVPVVFLTALFGLADLAGIRAGESVLI
MUL_2005|M.ulcerans_Agy99           PLSVVDQQLITRMPQGWSFAQAAAVPVVFLTALFGLQDLAKIQPGESVLI
MMAR_3099|M.marinum_M               PLAVVDARLLVRVPSGWSLAEAAGVPVAFLTAWYGLADLAGVRAGESVLV
MAV_3108|M.avium_104                SEAAVDRRLVTRVPPGWSMAQAAGIPVVFLTAYYGLSVLAGLRAGQRVLV
Rv2048c|M.tuberculosis_H37Rv        TVASTDQRLLVKVPAGWSHTAAATTSVVFATAHYALVDLAAARSGQRVLI
TH_4458|M.thermoresistible__bu      QMPEVSDDTVDELLRQLLAAGENHDDTQLH--------------------
                                        .    :  :      .      .                       

Mflv_0405|M.gilvum_PYR-GCK          HAASGGVGLAAVQMAQQCGAEVYATASTFKRATLRKLGVK--HVYDSRTT
MAB_0939|M.abscessus_ATCC_1997      HAASGGVGLAAIQMAQQFGAEVFATASTFKRATLRKLGVK--YVYDSRTT
MSMEG_0408|M.smegmatis_MC2_155      HAASGGVGLAAIQMAQQSGAEVFATASTFKRSTLRRLGVK--YVYDSRTT
Mvan_1003|M.vanbaalenii_PYR-1       HAASGGVGLAAVQLARQRGATVFATASGYKRPMLRAMGVD--HVYDSRTT
Mb2971c|M.bovis_AF2122/97           HAGTGGVGMAAVQLARQWGVEVFVTASRGKWDTLRAMGFDDDHIGDSRTC
MLBr_00135|M.leprae_Br4923          HAGTGGVGMAAVQFARHWGVEIFVTASRGKWDTLRDMGFDDDHIGDSRTL
MUL_2005|M.ulcerans_Agy99           HAGTGGVGMAAVQLARHWGVEIFVTASRGKWDTLRAMGFDDDHIGDSRTL
MMAR_3099|M.marinum_M               HAGTGGVGMAAVQLARLWGAKVFVTASRGKWDTLRSMGFDDSRIGDSRSL
MAV_3108|M.avium_104                HAATGGVGMAAVQLARHWGAEVFATASRGKWDTLRAMGFDDAHIADSRTL
Rv2048c|M.tuberculosis_H37Rv        HAGTGGVGMAAVQLARHLGLEVFATASKGKWDTLRAMGFDDDHISDSRSL
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          DFAEQILADTDGAGVDVVLNSLTSEGFIEATLRATAQHGRFAEIAKRDIW
MAB_0939|M.abscessus_ATCC_1997      DFADQILADTDGAGVDVVLNSLTSEGFIEATLRATAKNGRFAEIAKRDIW
MSMEG_0408|M.smegmatis_MC2_155      DFADQILADTNGAGVDVVLNSLTSAGFVEATLKATAQGGRFAEIAKRDIW
Mvan_1003|M.vanbaalenii_PYR-1       DFADQILADTDGAGVDVVLNSLTNDGFVAATVRATARNGRFAEIAKRDIW
Mb2971c|M.bovis_AF2122/97           EFEEKFLAVTEGRGVDVVLDSLAGE-FVDASLRLLVRGGRFLEMGKTDIR
MLBr_00135|M.leprae_Br4923          EFEEKFLAVTDGRGVDVVLDSLAGD-FVDASLRLLVRGGRFLEMGKTDIR
MUL_2005|M.ulcerans_Agy99           DFEEKFLAVTDGRGVDVVLDSLAGD-FVDASLRLLVRGGRFLEMGKTDIR
MMAR_3099|M.marinum_M               EFAEKFFAATRGRGVDVVLNSLAGE-FVDASLRLLAPGGRFIEMGKTDIR
MAV_3108|M.avium_104                DFEQKFGAAPGG--MDVVLNSLAGE-FNDASLRLLGPGGRFIEMGKTDLR
Rv2048c|M.tuberculosis_H37Rv        EFEDKFRAATGGRGFDVVLDSLAGE-FVDASLRLVAPGGVFLEMGKTDIR
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          TVEQMAAARPDLAYEIVALDTVMFTEPDRIRDLLTEVSAGLRDGAWTPLP
MAB_0939|M.abscessus_ATCC_1997      TTEQMAQSRPDIAYEIVALDTVMFQEPDRIRVLLTEVSEGLAKGEWTPLP
MSMEG_0408|M.smegmatis_MC2_155      SHEQMAEARPDIAYEIVALDTVMFTEPDRIRDLLTEVSDGMARGEWTPLP
Mvan_1003|M.vanbaalenii_PYR-1       SPEQMAAARPDIDYEVLALDAVMQQDPDRIQLLLADLADSLARGETAPLP
Mb2971c|M.bovis_AF2122/97           DAQEIAANYPGVQYRAFDLSEAG---PARMQEMLAEVRELFDTRELHRLP
MLBr_00135|M.leprae_Br4923          DAQEIAANYPGVQYRAFDLSEAG---PVRMQEMLCEVRELFDTQVLHRLP
MUL_2005|M.ulcerans_Agy99           DADKIAANYPGVWYRAFDLSEAG---PVRMQEMLAEVRELFDTAVLHRLP
MMAR_3099|M.marinum_M               DPQQIAVEYPGVIYEAFDLIEAG---PARIQPMLGQLHTLFEASALESLP
MAV_3108|M.avium_104                DPDVVARAHPGVRYRAFDLMEAG---PDRIAAMLAEVMELFAAGALTPLP
Rv2048c|M.tuberculosis_H37Rv        DPGVIAQQYPGVRYRAFDLFEPG---PDRIAQILAELATLFGDGVLRPLP
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          AEVYPLTEARAAFRRMQQARHIGKIVVQIPNPLQP-QPDRSYLITGGLGA
MAB_0939|M.abscessus_ATCC_1997      AEIYPLTEARTAFRRMQQARHIGKIVCQMPNPLAP-RPDRTYLITGGLGA
MSMEG_0408|M.smegmatis_MC2_155      AEIYPITEARSAFRRMQQARHIGKIVLQVPKPLQP-QQDRSYLITGGLGA
Mvan_1003|M.vanbaalenii_PYR-1       FEAYPLAEATTAFRRMQQARHTGKIILQMPKPLQP-HGDRSYLITGGLGA
Mb2971c|M.bovis_AF2122/97           VTTWDVRCAPAAFRFMSQARHIGKVVLTMPSALADRLADGTVVITGATGA
MLBr_00135|M.leprae_Br4923          VTSWDVRCAPAAFRFMSQARHIGKVVLTMPSALADGLAEGTVLITGASGA
MUL_2005|M.ulcerans_Agy99           VTTWDVRCAPAAFRFMSQARHIGKVVLTMPSALADGLADATVLITGATGA
MMAR_3099|M.marinum_M               TRTWDARCAPAAYRFVSQARQIGKVVLTMPTQISDAVAAGTVLITGGTGM
MAV_3108|M.avium_104                VKAFDARCAADAYRFVSAARHIGKVVLTMPDGPAG-LSGGTALITGATGM
Rv2048c|M.tuberculosis_H37Rv        VTTFDVRCAPAALRYLSQARHTGKVVMLMP----GSWAAGTVLITGGTGM
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          IG-LHTAGYLAQLGAGDIVLTSRRAPDAAAQQAIADIADRTKARLHVFTA
MAB_0939|M.abscessus_ATCC_1997      IG-LHTAAYLAQLGAGDIVLTSRRAPDTDAQRVIGEITERSKTRIHVFTA
MSMEG_0408|M.smegmatis_MC2_155      IG-LHTAAYLAQLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAA
Mvan_1003|M.vanbaalenii_PYR-1       LG-LHAAAYLAQLGAGDIVLTGRRMPDAATERAISEIAERYHCRIHTFAA
Mb2971c|M.bovis_AF2122/97           VGGVLARHLVGAYGVRHLVLASRRGDRAEGAAELAADLTEAGAKGQVVAC
MLBr_00135|M.leprae_Br4923          IGGVLARHMVSAYGVRHLVLASRRGDRAEGAVELAAELVGAGAKIQVVAC
MUL_2005|M.ulcerans_Agy99           VGAVLARHMLDGYGVRHLVLASRRGDRAEGAAELAAELSEAGANVQVVAC
MMAR_3099|M.marinum_M               VASVLARHLVSSYGVKHVVLASRRADATAGVAELVADLAAAGAAVAVVAC
MAV_3108|M.avium_104                AGAALARHLVARHRVPHLMLVGRRGEAAPGMAELAAELRGAGASVSVLSC
Rv2048c|M.tuberculosis_H37Rv        AGSAVARHVVARHGVRNLVLVSRRGPDAPGAAELVAELAAAGAQVQVVAC
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          DVGVEADVAALLERIRAELPPLAGVAHLAGVLDDALLSQQSVERFRTALA
MAB_0939|M.abscessus_ATCC_1997      DVGAESEVAGLLERIRAELPPLAGVAHLAGVLDDALLGQQSVERFRTTLA
MSMEG_0408|M.smegmatis_MC2_155      DVGDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLA
Mvan_1003|M.vanbaalenii_PYR-1       DVGDESAVRDLLERIRTELPPLAGVAHLAGVLDDALLPQQSPERFRTTLA
Mb2971c|M.bovis_AF2122/97           DVADRAAVAGLFAQLSREYPPVRGVIHAAGVLDDAVITSLTPDRIDTVLR
MLBr_00135|M.leprae_Br4923          DVADNDAVRGLFAQLSREFPPVRGVIHAAGVLDDGAITSLTPDRVDTVLR
MUL_2005|M.ulcerans_Agy99           DVADRDAVEAMLARLSGEYPPVRGVIHAAGVLDDAVISSLTPERIDTVLR
MMAR_3099|M.marinum_M               DVADRAAVTRLLDHVSTCHPPLTGVIHAAGTLDDAVIASLTPDRVDAVLR
MAV_3108|M.avium_104                DVGDRDAVAAMLAQVPARYP-LRSVFHAAGVLDDAVIASLTPARIDTVLR
Rv2048c|M.tuberculosis_H37Rv        DAADRAALAKVIADIPVQHP-LSGVIHTAGALDDAVVMSLTPDRVDVVLR
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          PKAFGAVHLDRLTRVDDLDFFLVSSSVSSLFGSPGQSNYATANAFLDGLV
MAB_0939|M.abscessus_ATCC_1997      PKAFGAEYLDRLTKGDDLDFFIVSSSVSSLFGSPGQSNYATANALLDGLI
MSMEG_0408|M.smegmatis_MC2_155      PKAYGASHLDRLTRDDDLDFFIVSSSVSSLFGSPGQANYATANAMLDGLV
Mvan_1003|M.vanbaalenii_PYR-1       PKAFGAWHLHRLTRDTELEFFIVYSSGSSVLGSPGQANYATANAVLDGLV
Mb2971c|M.bovis_AF2122/97           AKVDAAWNLHQATSDLDLSMFVLCSSIAATVGSPGQGNYSAANAFLDGLA
MLBr_00135|M.leprae_Br4923          AKVDAAWNLHEATRDLDLLMFVLCSSIAATVGSPGQGNYSAANAFLDGLA
MUL_2005|M.ulcerans_Agy99           AKVDAAWNLHEATLDLDLSMFVLCSSIAATVGSPGQGNYSAANSFLDGLA
MMAR_3099|M.marinum_M               AKVDGAWNLHEATRHLGLSMFVLCSSIAATVGSSGQANYAAGNAFLDGLA
MAV_3108|M.avium_104                AKVDGAWNLHELTKDLDLSAFVVFSSMAGIVGAPGQGNYAAANSFLDALA
Rv2048c|M.tuberculosis_H37Rv        SKVDAAWHLHELTRDLDVSAFVMFSSMAGLVGSSGQANYAAANSFLDALA
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          AQRRAQGLPATGVNFGPWARGGMASSEAAAAN---ISAQGLIPLEPSAAL
MAB_0939|M.abscessus_ATCC_1997      AQRRAQGLPATGINFGPWGQGGMASSEAATAN---ISAQGLIPLDPSAAL
MSMEG_0408|M.smegmatis_MC2_155      AKRRAQGLVATGINFGPWGQGGMASSEAATAN---ITAQGLIPLDPSAAL
Mvan_1003|M.vanbaalenii_PYR-1       AHRKARGLPATGVNWGPWAQGGMATSDAARAN---LGAQGLIPLEPTAAL
Mb2971c|M.bovis_AF2122/97           AHRQAAGLAGISLAWGLWEQPGGMTAHLSSRDLARMSRSGLAPMSPAEAV
MLBr_00135|M.leprae_Br4923          AYRQAAGLAGTSLAWGLWEQPGGMNAHLSSRDLARISRSGLAPMNPAQAL
MUL_2005|M.ulcerans_Agy99           AHRQAAGLAGISVAWGLWEQSGGMAAHLSSRDLARMSRSGLAPMNPEQAV
MMAR_3099|M.marinum_M               AYRRAGGLPGMSLGWGLWEQSSTMTAHLSDRDMARIRRIGLAAISPEQAM
MAV_3108|M.avium_104                IHRHAHGLPALSVAWGMWEEPSAMTAHLEERDKARMSRAGLSALSTRQAL
Rv2048c|M.tuberculosis_H37Rv        AHRRAHGLPAISLGWGLWDQASAMTGGLATVDFKRFARDGIVAMSSADAL
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          TAMAEVVANGTAQATVLKAN-WQRAAKVLGSSRPPILDLVLPSAVG----
MAB_0939|M.abscessus_ATCC_1997      AALAEVVANGTGQATILKAN-WQRAAKVLGSSRPPILDLVLPSAVG----
MSMEG_0408|M.smegmatis_MC2_155      HALAEVIANGSGQATVLKAN-WQRAAKVLGSARPPILDLVLPSAAG----
Mvan_1003|M.vanbaalenii_PYR-1       NALGEIVAHGIASAVVLKAN-WQRAAKLLGATRPPILDHVLPSAVA----
Mb2971c|M.bovis_AF2122/97           ELFDAALAIDHPLAVATLLDRAALDARAQAGALPALFSGLARRPRRRQID
MLBr_00135|M.leprae_Br4923          ELFDAALVIDHPFMVTALLDRAALDAQAQAGALPPLFSRLVRRSRRRQIE
MUL_2005|M.ulcerans_Agy99           GLLDAVLAINHPLMVATLLDRPALEARAQAGGLPPLFAGVVRRPRRRQIE
MMAR_3099|M.marinum_M               QLFDAALAVGQPTVLAAHLDHAVLANHTLSSTLPPLFSTLIKRPLRRLVD
MAV_3108|M.avium_104                DLLDDALLGEQPLVVGTRLDRAALAQHRAA--LPPLLSELAGRPARRMLE
Rv2048c|M.tuberculosis_H37Rv        QLFDTAMIVDEPFMLPAHIDFAALKVKFDGGTLPPMFVDLINAPTRRQVD
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          ----EITGDSELLKQLQEIPVPQRAGFVTEFLQKEVQNFLRLAQPP--AA
MAB_0939|M.abscessus_ATCC_1997      ----EVTGDSELLKQLMEIPVPQRAGFVTEFLQREVQNFLRLAQPP--AA
MSMEG_0408|M.smegmatis_MC2_155      ----EATGDSELLKQLMEIPIPQRAGFVTEFLQREVQNFLRLASPP--AA
Mvan_1003|M.vanbaalenii_PYR-1       ----AGPGDSALLKQLQDVPEAQRGSFVTEHLQRELQQILGLAQPP--AA
Mb2971c|M.bovis_AF2122/97           DTGDATSSKSALAQRLHGLAADEQLELLVGLVCLQAAAVLGRPSAEDVDP
MLBr_00135|M.leprae_Br4923          DPGDATQSKLALVQRLQGLAANRQLELLVGVVCLQAAAVLGRPSPEDIDP
MUL_2005|M.ulcerans_Agy99           DTGDAAQSKSALAERLNGLSAGERQDALVGLVCLQAAAVLGRPSPEDIDP
MMAR_3099|M.marinum_M               N--DTPSSTAGFAQRLYGLKPEKQQDLLVDLVCTQAAAVLGHPSATDLNP
MAV_3108|M.avium_104                HT--DMVSLTGLRARLAGMNPEQRQAELVELVCGNAAAVLG-HSTADVDP
Rv2048c|M.tuberculosis_H37Rv        DSLAAAKSKSALLQRLEGLPEDEQHAVLLDLVRSHIATVLGSASPEAIDP
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          TSRFLDLGTDSLMAIELRNRLHSQFGGAFTINATAVFDYPTIGGLAEYLV
MAB_0939|M.abscessus_ATCC_1997      TSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLV
MSMEG_0408|M.smegmatis_MC2_155      SSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLV
Mvan_1003|M.vanbaalenii_PYR-1       TGRFLELGMDSLMAVELRNRLVGQFGSGFTITATAVFDYPTIGALAEYLA
Mb2971c|M.bovis_AF2122/97           DTEFGDLGFDSLTAVELRNRLKTATG--LTLPPTVIFDHPTPTAVAEYVA
MLBr_00135|M.leprae_Br4923          NTKFQDLGFDSLTAVELRNRLKSATG--LTLPPTVIFDHPTPTAVAEYVA
MUL_2005|M.ulcerans_Agy99           EAGFQDLGFDSLTAVELRNRFKSATG--LTLPPTVIFDHPTPTAIAEYVG
MMAR_3099|M.marinum_M               ASTFQNMGFDSLTAVELRNRLKTVTG--LGLSPTLVFDHPTPTALAGLIA
MAV_3108|M.avium_104                GDAFSDLGFDSLTAVELRNRLKIATG--LTLSPTVIFDHPTPAALAEHLG
Rv2048c|M.tuberculosis_H37Rv        DRAFQELGFDSLTAVEMRNRLKSATG--LALSPTLIFDYPNSAALAGYMR
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          AQLPDAET----------------------------------PQAAP---
MAB_0939|M.abscessus_ATCC_1997      GQLPDADA----------------------------------ESAEAPPA
MSMEG_0408|M.smegmatis_MC2_155      GQLPDAEA----------------------------------PETA----
Mvan_1003|M.vanbaalenii_PYR-1       AQTPESTE----------------------------------EGTEMKTA
Mb2971c|M.bovis_AF2122/97           QQMSGSRP---------------------------------TESGDPTSQ
MLBr_00135|M.leprae_Br4923          QQMLKSRP---------------------------------AESGDETSQ
MUL_2005|M.ulcerans_Agy99           RQIPDSQA---------------------------------TQAEEE--K
MMAR_3099|M.marinum_M               ELIGIAAKGLSPLEEALNNVEE---------------TLPAIEAGDKHRV
MAV_3108|M.avium_104                GQLTSAGPTPAAPAETAAPPDRSSRIDEVVSELQTLLTQPGLSPGDRAQL
Rv2048c|M.tuberculosis_H37Rv        RELLGSSPQDTSAVAAGEAELQR---------------IVASIPVKRLRQ
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          ----QSESEPGPDVTE---------------------------------
MAB_0939|M.abscessus_ATCC_1997      VESAEAESGAGPAAASDAVSELKE-------------------------
MSMEG_0408|M.smegmatis_MC2_155      -------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       DPDGQPATVGHADVVLQTS------------------------------
Mb2971c|M.bovis_AF2122/97           VVEPAAAEVSVHA------------------------------------
MLBr_00135|M.leprae_Br4923          AVEPKVEEVSVHA------------------------------------
MUL_2005|M.ulcerans_Agy99           LPESDGEMVSVTA------------------------------------
MMAR_3099|M.marinum_M               ADRLRALLSTITDEEHRLDERIQAASTLDEVLLLVDSELANLEKGPGL-
MAV_3108|M.avium_104                VTRLQSLLSTPPQPSG--HPEFPEDAFDDDIATATDSQLFAILDDEAGP
Rv2048c|M.tuberculosis_H37Rv        AGVLDLLLALANETETSGQDPALAPTAEQEIADMDLDDLVNAAFRNDDE
TH_4458|M.thermoresistible__bu      -------------------------------------------------