For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VTNRVQELLGVEFPVVQAPMTYIARAELAAAVSEGGGLGMVETLTPEGREDLLRVRDLTDRPVAANLMIQ GWKRDPSIVDTLAAAGVRHVFTSAGDPALFTARLHDAGMTVVHVVGSLKGALKAADAGVDALVVEGVEGG GFKSALGASTMVLLPLIADRVDLPIICAGGVCDARSGAAAVVLGAEGVQMGTRMLASVEAAVHTNFKDAI VAADDSGTVLLDVPGNPTMRVLRTGLAARIDEHPADAQLLGRITDLYFGGDMEASVANTGQVSSRITELR PVAEIVRQTWRGIESVLDSARTRLD
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5586 | - | - | 100% (305) | 2-nitropropane dioxygenase, NPD |
| M. vanbaalenii PYR-1 | Mvan_4576 | - | 4e-43 | 33.44% (302) | 2-nitropropane dioxygenase, NPD |
| M. vanbaalenii PYR-1 | Mvan_4537 | - | 3e-34 | 32.78% (299) | 2-nitropropane dioxygenase, NPD |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0021c | - | 6e-32 | 32.78% (299) | hypothetical protein Mb0021c |
| M. gilvum PYR-GCK | Mflv_1222 | - | 1e-152 | 88.82% (304) | 2-nitropropane dioxygenase, NPD |
| M. tuberculosis H37Rv | Rv0021c | - | 4e-32 | 32.78% (299) | hypothetical protein Rv0021c |
| M. leprae Br4923 | MLBr_00388 | guaB3 | 2e-07 | 24.07% (295) | inosine 5-monophosphate dehydrogenase |
| M. abscessus ATCC 19977 | MAB_4001c | - | 1e-73 | 50.83% (301) | putative 2-nitropropane dioxygenase, NPD |
| M. marinum M | MMAR_5042 | - | 9e-30 | 36.78% (242) | 2-nitropropane dioxygenase |
| M. avium 104 | MAV_2769 | - | 5e-90 | 59.86% (289) | oxidoreductase, 2-nitropropane dioxygenase family protein |
| M. smegmatis MC2 155 | MSMEG_5182 | - | 2e-42 | 33.75% (317) | 2-nitropropane dioxygenase |
| M. thermoresistible (build 8) | TH_3625 | - | 3e-42 | 32.80% (314) | PUTATIVE 2-Nitropropane dioxygenase |
| M. ulcerans Agy99 | MUL_1961 | - | 8e-30 | 28.80% (309) | hypothetical protein MUL_1961 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0021c|M.bovis_AF2122/97 --------------------------MVLSTAFSQMFGIDYPIVSAPMDL
Rv0021c|M.tuberculosis_H37Rv --------------------------MVLSTAFSQMFGIDYPIVSAPMDL
MUL_1961|M.ulcerans_Agy99 --------------------------MSLNTRLTEFLGVQHPILLAPMAM
Mvan_5586|M.vanbaalenii_PYR-1 ----------------------------MTNRVQELLGVEFPVVQAPMTY
Mflv_1222|M.gilvum_PYR-GCK ----------------------------MTNRIQDLLGVEFPVVQAPMTY
MAV_2769|M.avium_104 -----------------------------------------------MTY
MAB_4001c|M.abscessus_ATCC_199 ---------------------------MITNRVTELLGVERPIVQAPMGW
MSMEG_5182|M.smegmatis_MC2_155 --------------------------MALTTKFTEAFGVTHPIAQGGMQW
TH_3625|M.thermoresistible__bu --------------------------MPLTTKFTEAFGIEHPIAQGGMQW
MMAR_5042|M.marinum_M --------------------------MRLRTPLTDLVGVEHPVVQTGMGW
MLBr_00388|M.leprae_Br4923 MGRVARRTYELREISIVPSRRTRSSKDVSTAWQLDAYRFEIPVVAHPTDA
Mb0021c|M.bovis_AF2122/97 IAGGELAAAVSGAGGLGLIGGGYG----DRDWLARQFDLAAGAPVGCGFI
Rv0021c|M.tuberculosis_H37Rv IAGGELAAAVSGAGGLGLIGGGYG----DRDWLARQFDLAAGAPVGCGFI
MUL_1961|M.ulcerans_Agy99 TSGGRLAAAVTAAGGLGLIGGGYG----EAEWLQRQLEQAQGQRVGCGFI
Mvan_5586|M.vanbaalenii_PYR-1 IARAELAAAVSEGGGLGMVETLT----PEGREDLLRVRDLTDRPVAANLM
Mflv_1222|M.gilvum_PYR-GCK IARAELAAAVSDGGGLGMIETLT----DEGRADLLRVRDLTDRPVAANLM
MAV_2769|M.avium_104 IAGAQLAAAVSNAGALGIIETTS----DQGRADLRRVRELTAGAVGANIA
MAB_4001c|M.abscessus_ATCC_199 IARSQLASAVCNAGGLGIIETSSG-ELDAIKDEIRAMREFTDKPFGVNIA
MSMEG_5182|M.smegmatis_MC2_155 VGRAELVAAVANAGALGFITALTQPTPADLANEIARCRDLTDKPFGVNLT
TH_3625|M.thermoresistible__bu VGRAELVAAVANAGALGFITALTQPTPKDLANEIARCRDLTDKPFGVNLT
MMAR_5042|M.marinum_M VAGARLVSATANAGGLGILASATM-TLDELATAIGKVKATTDKPFGVNIR
MLBr_00388|M.leprae_Br4923 LVSPEFAIELGRLGGLGVLNGEG------------LIGRHADVGAKVAQL
.:. *.**.:
Mb0021c|M.bovis_AF2122/97 TWSLARQP---QLLDLALQYEPVAVMLSFGDPAVFADAIKSAGTRLVCQI
Rv0021c|M.tuberculosis_H37Rv TWSLARQP---QLLDLALQYEPVAVMLSFGDPAVFADAIKSAGTRLVCQI
MUL_1961|M.ulcerans_Agy99 TWSLARNP---ELLDLILAANPAAIMLSFGDPHNFAGPIHDAGIPLICQI
Mvan_5586|M.vanbaalenii_PYR-1 IQGWKRDP---SIVDTLAAAGVRHVFTSAGDPALFTARLHDAGMTVVHVV
Mflv_1222|M.gilvum_PYR-GCK IQGWKRDP---SIVDVLAAAGVRHVFTSAGDPALFTDRLHDAGMTVVHVI
MAV_2769|M.avium_104 LL-FNRDP---AMLDLLVANDIRFVTTSAGDPALFTDRLHDAGITVFHVV
MAB_4001c|M.abscessus_ATCC_199 QA-FVRDP---SIAQFVVDQGVTFVTTSAGDPNKYTRVLKDNGLTVFHVV
MSMEG_5182|M.smegmatis_MC2_155 ILPSINPPPYDEYRQVIVDSGVKIVETAGSNPAPHLPMFHDNGIKVLHKC
TH_3625|M.thermoresistible__bu ILPTISPPPYDEYRRVIIDSGVKVVETAGSNPAPHLSHFHDNGIKVLHKC
MMAR_5042|M.marinum_M ADAADAS----DRVELMIREGVKVASFALAPKPELIARLKEAGAVVIPSI
MLBr_00388|M.leprae_Br4923 IEAAEKEP--EPATAVCLLQELHAAPLNPDLLGSAVARIREAGVTTAVRV
::. *
Mb0021c|M.bovis_AF2122/97 QNRTQAER---ALQVGADVLVAQGTEAGGHGHGPRSTLTLVPEIVDLVTA
Rv0021c|M.tuberculosis_H37Rv QNRTQAER---ALQVGADVLVAQGTEAGGHGHGPRSTLTLVPEIVDLVTA
MUL_1961|M.ulcerans_Agy99 HTREQALR---VLEVGPDIIVAQGSESGGHGMSVRSTFTLVPDVVDLVAQ
Mvan_5586|M.vanbaalenii_PYR-1 GSLKGALK---AADAGVDALVVEGVEGGGFKS-ALGASTMV---LLPLIA
Mflv_1222|M.gilvum_PYR-GCK GSLKGALK---AADAGVDALVVEGVEGGGFKS-ALGASTMV---LLPLVA
MAV_2769|M.avium_104 GTLAAAKK---AVDAGVDGLVVEGVEGGGFKN-RFGASTMV---LLPLVA
MAB_4001c|M.abscessus_ATCC_199 PTLAAALK---AVDAGVDGLVVEGVEGGGFKD-PKGASTMV---LLPLVR
MSMEG_5182|M.smegmatis_MC2_155 TSVRHAVK---AQSLGVDGISIDGFECAGHPG-EDDIPGLV---LIPAAA
TH_3625|M.thermoresistible__bu TSVRHAVK---AQELGVDGISIDGFECAGHPG-EDDIPGLV---LIPAAA
MMAR_5042|M.marinum_M GAAKHARK---VAGWGADAMIVQGGEGGGHTGPVATTLLLP---SVLDAV
MLBr_00388|M.leprae_Br4923 SPQNAQVLTPVLLAAGIDLLVVQG-SIVSAECVASGGEPLN----LKTFI
* * : :* . . :
Mb0021c|M.bovis_AF2122/97 RGTDIPVIAAGGIADGRGLAAALMLGAAGVLVG---TRFYATVEALSTPQ
Rv0021c|M.tuberculosis_H37Rv RGTDIPVIAAGGIADGRGLAAALMLGAAGVLVG---TRFYATVEALSTPQ
MUL_1961|M.ulcerans_Agy99 RSAETLVVAAGGIADGRGLAAALALGADGALVG---TRFWACPEALVSPR
Mvan_5586|M.vanbaalenii_PYR-1 DRVDLPIICAGGVCDARSGAAAVVLGAEGVQMG---TRMLASVEAAVHTN
Mflv_1222|M.gilvum_PYR-GCK ERVDLPLICAGGICDARSAAAAVVLGAEGIQMG---TRMLASAEALVHAN
MAV_2769|M.avium_104 AHVDVPIVAAGGICDARSMAAAFVLGAEAVQMG---TRLLASADSPVHVN
MAB_4001c|M.abscessus_ATCC_199 SHVDIPIIAAGGICDGVSMAAAFALGAEGVQMG---TRMMSAAESPIHHN
MSMEG_5182|M.smegmatis_MC2_155 DKIEIPMIASGGFADGRGLAAALALGADGINMG---SRFMCTVESSIHQN
TH_3625|M.thermoresistible__bu KQIEIPMIASGGFADARGLVAALALGADGINMG---SRFMCTVESPVHQK
MMAR_5042|M.marinum_M KGTGIPVIAAGGFFDGRGLAAALSYGAAGVAMG---TRFLLTSDSTVPEA
MLBr_00388|M.leprae_Br4923 SELDVPVVAGG-VLDHRTALHLMRTGAAGVIVGYGSTRGATTSDEVLGIS
::..* . * . ** . :* :* :
Mb0021c|M.bovis_AF2122/97 ARDPLLAATGDDMCRTTIYDQLRRYPWPQGHTMSVLSNALTDQFEDTELD
Rv0021c|M.tuberculosis_H37Rv ARDPLLAATGDDMCRTTIYDQLRRYPWPQGHTMSVLSNALTDQFEDTELD
MUL_1961|M.ulcerans_Agy99 AHQRAVEASGDDTIRTRVYDIVRQRDWPAEYDLRLLSNSLIQAWHGNESE
Mvan_5586|M.vanbaalenii_PYR-1 FKDAIVAADDSGTVLLDVPGNPTMRVLRTGLAARIDEHPAD---AQLLG-
Mflv_1222|M.gilvum_PYR-GCK FKDAIVAADDAGTILLDVPGNPTMRVLRTGLAARIDEQDAD---AKLLG-
MAV_2769|M.avium_104 LKQAVVAADETATVLLPLDGKRMMRVIRTPAAERLEAAGAAGEGAAALQ-
MAB_4001c|M.abscessus_ATCC_199 WKAAVVAARETDTVLLNRLTKPGLRALRSARTEEMERRDLVS--LLETG-
MSMEG_5182|M.smegmatis_MC2_155 VKEAIVAGDERGTELIFRTLHNTARVASN---------KVSREVVEILNK
TH_3625|M.thermoresistible__bu VKEAIVAGDERGTELIFRTLGNTGRVASN---------SVSREVVRILAD
MMAR_5042|M.marinum_M VKRRYLQAALDGTVVTTRVDGMPHRVLRTGLVEKLEGGSRARGFTAAIRN
MLBr_00388|M.leprae_Br4923 VPMATAIADAAAARREYLDETGGRYVHVLADGDIYTSGELAKAIACGADA
.
Mb0021c|M.bovis_AF2122/97 ILHR--------------EEAMARYWRAVPARDYSIANVTAGQAAGLVNA
Rv0021c|M.tuberculosis_H37Rv ILHR--------------EEAMARYWRAVAARDYSIANVTAGQAAGLVNA
MUL_1961|M.ulcerans_Agy99 LIRRL-------------PDLLGAFENAVAAEDFEMATVLVGEAVGLISR
Mvan_5586|M.vanbaalenii_PYR-1 -----------------------RITDLYFGGDMEASVANTGQVSSRITE
Mflv_1222|M.gilvum_PYR-GCK -----------------------RITDLYFGGDLEASVANTGQVSSRITG
MAV_2769|M.avium_104 -----------------------RVQRLYFEGDLDASVANTGQVAGRIRD
MAB_4001c|M.abscessus_ATCC_199 -----------------------DPLDLYFGGNMETFVPLGGQVAGRIGG
MSMEG_5182|M.smegmatis_MC2_155 GGQFEDVKDLVAG---------VRGRKVFENGDVDAGIWTVGTAMGLIDD
TH_3625|M.thermoresistible__bu GGRFEDVRDLVSG---------ARGARVYETGDLEAGIWWIGTSMGLIDD
MMAR_5042|M.marinum_M AAKFKQMSQMSWASMIKDGLAMRHGKELTWSQVVMAANTPMLLKAGLVDG
MLBr_00388|M.leprae_Br4923 VVLGTPLAQS---------AEALGGGWFWPAAAAHPSLPRGALLQTAVGE
:
Mb0021c|M.bovis_AF2122/97 VLPAADVITGMAQ-------QAARTLTAMRAV------------------
Rv0021c|M.tuberculosis_H37Rv VLPAADVITGMAQ-------QAARTLTAMRAV------------------
MUL_1961|M.ulcerans_Agy99 VGPAADIVSEMVC-------DATRILNRSG--------------------
Mvan_5586|M.vanbaalenii_PYR-1 LRPVAEIVRQTWR-------GIESVLDSARTRLD----------------
Mflv_1222|M.gilvum_PYR-GCK LAPAAEIVRQTWC-------EIQTVLDDTRARLG----------------
MAV_2769|M.avium_104 LPPAADIIKQMWK-------GCREVLAATSARLDWADDA-----------
MAB_4001c|M.abscessus_ATCC_199 VESVKDILDATMD-------EFTAVIGKLAAQYV----------------
MSMEG_5182|M.smegmatis_MC2_155 IPTVQDLVTRIVR-------DAEVLISGRLLNMISADEPDAEKETVPA--
TH_3625|M.thermoresistible__bu IPTVGTLLSRIIR-------DAEHLIEGRLQAMVRS--PAGADQ------
MMAR_5042|M.marinum_M NPEAGVLASGQVAGILDDLPSCAQLVESIVHDAIEHLRAAAALVE-----
MLBr_00388|M.leprae_Br4923 RPSLQQVLNGPSD----NPFGTLNLVGGLRRSMAKAGYCDLKEFQKVGLI
: :
Mb0021c|M.bovis_AF2122/97 ---
Rv0021c|M.tuberculosis_H37Rv ---
MUL_1961|M.ulcerans_Agy99 ---
Mvan_5586|M.vanbaalenii_PYR-1 ---
Mflv_1222|M.gilvum_PYR-GCK ---
MAV_2769|M.avium_104 ---
MAB_4001c|M.abscessus_ATCC_199 ---
MSMEG_5182|M.smegmatis_MC2_155 ---
TH_3625|M.thermoresistible__bu ---
MMAR_5042|M.marinum_M ---
MLBr_00388|M.leprae_Br4923 VSI