For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. thermoresistible (build 8) TH_3625 (-)

annotation: 2-Nitropropane dioxygenase
coordinates: 3001233 - 3002228
length: 332

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3625--100% (332)2-Nitropropane dioxygenase
M. thermoresistible (build 8)TH_3584-e-15984.16% (322) PUTATIVE 2-nitropropane dioxygenase, NPD
M. thermoresistible (build 8)TH_2580-e-15782.66% (323) PUTATIVE 2-nitropropane dioxygenase, NPD

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3583-7e-3731.71% (350) oxidoreductase
M. gilvum PYR-GCKMflv_2128-1e-15782.66% (323) 2-nitropropane dioxygenase, NPD
M. tuberculosis H37RvRv3553-7e-3731.71% (350) oxidoreductase
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4001c-1e-4132.29% (319) putative 2-nitropropane dioxygenase, NPD
M. marinum MMMAR_5042-1e-3631.36% (354) 2-nitropropane dioxygenase
M. avium 104MAV_0607-1e-3732.00% (350) oxidoreductase, 2-nitropropane dioxygenase family protein
M. smegmatis MC2 155MSMEG_5182-1e-15985.14% (323) 2-nitropropane dioxygenase
M. ulcerans Agy99MUL_4116-6e-3631.07% (354) 2-nitropropane dioxygenase
M. vanbaalenii PYR-1Mvan_4576-1e-15882.57% (327) 2-nitropropane dioxygenase, NPD

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_5042|M.marinum_M               --MRLRTPLTDLVGVEHPVVQTGMGWVAGARLVSATANAGGLG-ILASAT
MUL_4116|M.ulcerans_Agy99           --MRLRTPLTDLVGVEHPVVQTGMGWVAGARLVSATANAGGLG-ILASAT
MAV_0607|M.avium_104                MDMRLRTPLTELVGVEHPVVQTGMGWVAGARLVSATANAGGLG-ILASAT
Mb3583|M.bovis_AF2122/97            --MRLRTPLTELIGIEHPVVQTGMGWVAGARLVSATANAGGLG-ILASAT
Rv3553|M.tuberculosis_H37Rv         --MRLRTPLTELIGIEHPVVQTGMGWVAGARLVSATANAGGLG-ILASAT
Mflv_2128|M.gilvum_PYR-GCK          --MTITTKFTETFGVEHPIAQGGMQWVGRAELVAAVANAGALGFITALTQ
Mvan_4576|M.vanbaalenii_PYR-1       --MTIRTKFTETFGVEHPIAQGGMQWVGRAELVAAVANAGALGFITALTQ
MSMEG_5182|M.smegmatis_MC2_155      --MALTTKFTEAFGVTHPIAQGGMQWVGRAELVAAVANAGALGFITALTQ
TH_3625|M.thermoresistible__bu      --MPLTTKFTEAFGIEHPIAQGGMQWVGRAELVAAVANAGALGFITALTQ
MAB_4001c|M.abscessus_ATCC_199      ---MITNRVTELLGVERPIVQAPMGWIARSQLASAVCNAGGLGIIETSSG
                                        : . .*: .*: :*:.*  * *:. :.*.:*..***.** * : : 

MMAR_5042|M.marinum_M               MTLDELATAIGKVKATTDKPFGVNIRADAADASDR----VELMIREGVKV
MUL_4116|M.ulcerans_Agy99           MTLDELATAIGKVKATTDKPFGVNIRADAADASDR----VELMIREGVKV
MAV_0607|M.avium_104                MTLDELATAIAKVKAATDKPFGVNIRADAADAADR----VDLMIREGVKV
Mb3583|M.bovis_AF2122/97            MTLDELAAAITKVKAVTDKPFGVNIRADAADAGDR----VELMIREGVRV
Rv3553|M.tuberculosis_H37Rv         MTLDELAAAITKVKAVTDKPFGVNIRADAADAGDR----VELMIREGVRV
Mflv_2128|M.gilvum_PYR-GCK          PTPADLANEIARTRDLTDKPFGVNLTILPAINPPPYDEYRQVIVDAGIKI
Mvan_4576|M.vanbaalenii_PYR-1       PTPADLANEIAKTRDLTDKPFGVNLTILPAINPPPYDEYRQVIVDAGIKI
MSMEG_5182|M.smegmatis_MC2_155      PTPADLANEIARCRDLTDKPFGVNLTILPSINPPPYDEYRQVIVDSGVKI
TH_3625|M.thermoresistible__bu      PTPKDLANEIARCRDLTDKPFGVNLTILPTISPPPYDEYRRVIIDSGVKV
MAB_4001c|M.abscessus_ATCC_199      -ELDAIKDEIRAMREFTDKPFGVNIAQAFVRDPS----IAQFVVDQGVTF
                                         :   *   :  ********:                .::  *: .

MMAR_5042|M.marinum_M               ASFALAPKPELIARLKEAGAVVIPSIGAAKHARKVAGWGADAMIVQGGEG
MUL_4116|M.ulcerans_Agy99           ASFALAPKPELIARLKEAGAVVIPSIGAAKHARKVAGWGADAMIVQGGEG
MAV_0607|M.avium_104                ASFALAPKQELIARLKEAGAVVIPSIGAAKHARKVAGWGADAMIVQGGEG
Mb3583|M.bovis_AF2122/97            ASFALAPKQQLIARLKEAGAVVIPSIGAAKHARKVAAWGADAMIVQGGEG
Rv3553|M.tuberculosis_H37Rv         ASFALAPKQQLIARLKEAGAVVIPSIGAAKHARKVAAWGADAMIVQGGEG
Mflv_2128|M.gilvum_PYR-GCK          VETAGSNPAPHLPMFHDNGIKVLHKCTSVRHAVKAQSLGVDGISIDGFEC
Mvan_4576|M.vanbaalenii_PYR-1       VETAGSNPAPHLPMFHDNGIKVLHKCTSVRHAVKAQSLGVDGISIDGFEC
MSMEG_5182|M.smegmatis_MC2_155      VETAGSNPAPHLPMFHDNGIKVLHKCTSVRHAVKAQSLGVDGISIDGFEC
TH_3625|M.thermoresistible__bu      VETAGSNPAPHLSHFHDNGIKVLHKCTSVRHAVKAQELGVDGISIDGFEC
MAB_4001c|M.abscessus_ATCC_199      VTTSAGDPNKYTRVLKDNGLTVFHVVPTLAAALKAVDAGVDGLVVEGVEG
                                    .  : .        ::: *  *:    :   * *.   *.*.: ::* * 

MMAR_5042|M.marinum_M               GGHTGP--VATTLLLPSVLDAVKGTGIPVIAAGGFFDGRGLAAALSYGAA
MUL_4116|M.ulcerans_Agy99           GGHTGP--VATTLLLPSVLDAVKGTGIPVIAAGGFFDGHGLAAALSYGAA
MAV_0607|M.avium_104                GGHTGP--VATTLLLPSVLDAVRGTGIPVIAAGGFFDGRGLAAALSYGAA
Mb3583|M.bovis_AF2122/97            GGHTGP--VATTLLLPSVLDAVAGTGIPVIAAGGFFDGRGLAAALCYGAA
Rv3553|M.tuberculosis_H37Rv         GGHTGP--VATTLLLPSVLDAVAGTGIPVIAAGGFFDGRGLAAALCYGAA
Mflv_2128|M.gilvum_PYR-GCK          AGHPGEDDVPGLVLIPAAADKIE---IPMIASGGFADGRGLAAALALGAD
Mvan_4576|M.vanbaalenii_PYR-1       AGHPGEDDVPGLVLIPAAADKIE---IPMIASGGFADARGLVAALALGAD
MSMEG_5182|M.smegmatis_MC2_155      AGHPGEDDIPGLVLIPAAADKIE---IPMIASGGFADGRGLAAALALGAD
TH_3625|M.thermoresistible__bu      AGHPGEDDIPGLVLIPAAAKQIE---IPMIASGGFADARGLVAALALGAD
MAB_4001c|M.abscessus_ATCC_199      GGFKDPKGASTMVLLPLVRSHVD---IPIIAAGGICDGVSMAAAFALGAE
                                    .*. .    .  :*:* . . :    **:**:**: *. .:.**:. ** 

MMAR_5042|M.marinum_M               GVAMGTRFLLTSDSTVPEAVKRRYLQAALDGTVVTTRVDGMPHRVLRTGL
MUL_4116|M.ulcerans_Agy99           GVAMGTRFLLTSDSTVPDAVKRRYLQAALDGTVVTTRVDGMPHRVLRTGL
MAV_0607|M.avium_104                GVAMGTRFLLTSDSTVPDAVKKRYLEAALDGTVVTTRVDGMPHRVLRTGL
Mb3583|M.bovis_AF2122/97            GVAMGTRFLLTSDSTVPDAVKRRYLQAGLDGTVVTTRVDGMPHRVLRTEL
Rv3553|M.tuberculosis_H37Rv         GVAMGTRFLLTSDSTVPDAVKRRYLQAGLDGTVVTTRVDGMPHRVLRTEL
Mflv_2128|M.gilvum_PYR-GCK          GVNMGSRFMCTVESCIHQNVKEAIVAGDERGTELIFRSLHNTARVASNVV
Mvan_4576|M.vanbaalenii_PYR-1       GINMGSRFMCTVESCIHQNVKEAIVAGDERGTELIFRSLHNTARVASNEV
MSMEG_5182|M.smegmatis_MC2_155      GINMGSRFMCTVESSIHQNVKEAIVAGDERGTELIFRTLHNTARVASNKV
TH_3625|M.thermoresistible__bu      GINMGSRFMCTVESPVHQKVKEAIVAGDERGTELIFRTLGNTGRVASNSV
MAB_4001c|M.abscessus_ATCC_199      GVQMGTRMMSAAESPIHHNWKAAVVAARETDTVLLNRLTKPGLRALRSAR
                                    *: **:*:: : :* : .  *   : .   .* :  *      *.  .  

MMAR_5042|M.marinum_M               VEKLEGGSRARGFTAAIRNAAKFKQMSQMSWASMIKDGLAMRHGKELTWS
MUL_4116|M.ulcerans_Agy99           VEKLEGGSRARGFTAAIRNAAKFKQMSQMSWASMIKDGLAMRHGKELTWS
MAV_0607|M.avium_104                VEKLESGSPVRGLTAAVRNAAKFKHMSKMTWRSMISDGLAMRHGKEMTWS
Mb3583|M.bovis_AF2122/97            VEKLESGSRARGFAAALRNAGKFRRMSQMTWRSMIRDGLTMRHGKELTWS
Rv3553|M.tuberculosis_H37Rv         VEKLESGSRARGFAAALRNAGKFRRMSQMTWRSMIRDGLTMRHGKELTWS
Mflv_2128|M.gilvum_PYR-GCK          SREVVQILKEGGQFEDVKDLVAGVRGRKVFDD------------------
Mvan_4576|M.vanbaalenii_PYR-1       SREVVQILKDGGQFEDVKDLVAGVRGRKVFDD------------------
MSMEG_5182|M.smegmatis_MC2_155      SREVVEILNKGGQFEDVKDLVAGVRGRKVFEN------------------
TH_3625|M.thermoresistible__bu      SREVVRILADGGRFEDVRDLVSGARGARVYET------------------
MAB_4001c|M.abscessus_ATCC_199      TEEMER--------RDLVSLLETGDPLDLYFG------------------
                                     .::            : .         :                     

MMAR_5042|M.marinum_M               QVVMAANTPMLLKAGLVDGNPEAGVLASGQVAGILDDLPSCAQLVESIVH
MUL_4116|M.ulcerans_Agy99           QVLMAANTPMLLKAGLVDGNPEAGVLASGQVAGILDDLPSCAQLVESIVH
MAV_0607|M.avium_104                QVVMAANTPMLLKAGLVEGNTEAGVLASGQVAGILEDLPSCAELIDSIVR
Mb3583|M.bovis_AF2122/97            QVLMAANTPMLLKAGLVDGNTEAGVLASGQVAGILDDLPSCKELIESIVL
Rv3553|M.tuberculosis_H37Rv         QVLMAANTPMLLKAGLVDGNTEAGVLASGQVAGILDDLPSCKELIESIVL
Mflv_2128|M.gilvum_PYR-GCK          ------------------GDIDAGIWTVGTAMGLINDIPTVGDLVSRIVG
Mvan_4576|M.vanbaalenii_PYR-1       ------------------GDIDAGIWTVGTAMGLINDIPTVGELVSRIVG
MSMEG_5182|M.smegmatis_MC2_155      ------------------GDVDAGIWTVGTAMGLIDDIPTVQDLVTRIVR
TH_3625|M.thermoresistible__bu      ------------------GDLEAGIWWIGTSMGLIDDIPTVGTLLSRIIR
MAB_4001c|M.abscessus_ATCC_199      ------------------GNMETFVPLGGQVAGRIGGVESVKDILDATMD
                                                      *: :: :   *   * : .: :   ::   : 

MMAR_5042|M.marinum_M               DAIEHLRAAAALVE--------------
MUL_4116|M.ulcerans_Agy99           DAIEHLRAAAALVE--------------
MAV_0607|M.avium_104                DAIAHLRSASGLIEE-------------
Mb3583|M.bovis_AF2122/97            DAITHLQTASALVE--------------
Rv3553|M.tuberculosis_H37Rv         DAITHLQTASALVE--------------
Mflv_2128|M.gilvum_PYR-GCK          DAEEIISGRLAGMVS---PVAQRV----
Mvan_4576|M.vanbaalenii_PYR-1       EAEQLITGRLGEMVT---PTAARV----
MSMEG_5182|M.smegmatis_MC2_155      DAEVLISGRLLNMISADEPDAEKETVPA
TH_3625|M.thermoresistible__bu      DAEHLIEGRLQAMVR--SPAGADQ----
MAB_4001c|M.abscessus_ATCC_199      EFTAVIGKLAAQYV--------------
                                    :    :