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GRRRGAELDAAIRAAVLELLAEHGPDGVTMDAVAVTAQTSKPVLYRRWPDRRALLRDTLLGIATSAFPTV DTGGFRGDMLAVLRAWAALFTGDSAALMRSAIGAVTADPELAATFRTDVIGARKQEMDAIITRGVQRGEV RADVPVDLVRELGQSVLWHRLLISGDPIDDEVVTRLVDEVLIPVTRPYYEV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2727 | - | - | 100% (192) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5902 | - | 4e-19 | 34.57% (188) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1961 | - | 6e-16 | 29.78% (178) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1199c | - | 1e-19 | 30.81% (185) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_3683 | - | 1e-80 | 75.92% (191) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1167c | - | 1e-19 | 30.81% (185) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1497c | - | 4e-22 | 34.05% (185) | TetR family transcriptional regulator |
| M. marinum M | MMAR_1695 | - | 2e-16 | 28.57% (175) | regulatory protein |
| M. avium 104 | MAV_3866 | - | 2e-18 | 34.09% (176) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_5301 | - | 4e-18 | 29.83% (181) | transcriptional regulator |
| M. thermoresistible (build 8) | TH_3283 | - | 2e-13 | 28.49% (186) | PUTATIVE putative transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_1934 | - | 1e-16 | 28.57% (175) | regulatory protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_2727|M.vanbaalenii_PYR-1 -----------MGRRRGAELDAAIRAAVLELLAEHGPDGVTMDAVAVTAQ
Mflv_3683|M.gilvum_PYR-GCK ----------MMTRRRGAELDAAIRSAVLDLLAGHGPEAVTMDAVAVAAG
MAB_1497c|M.abscessus_ATCC_199 ------------MVARGETRSAALLAVALQVLIRDGYDRFSMDSVAALAH
MMAR_1695|M.marinum_M ---MTQTADRSAQVSPWSPREAELLAVTLQLLQEHGYDRLTIDAVANTAR
MUL_1934|M.ulcerans_Agy99 MGAMTQTADRSAQVSPWSPREAELLAVTLQLLQEHGYDRLTIDAVANTAR
MAV_3866|M.avium_104 ---MTQTADRCEQASPWSPREAEILAVTLRLLQEHGYDQLTVDAVAGAAH
Mb1199c|M.bovis_AF2122/97 -MTVSAPAKANPYRRRGEVLERALYDATLAELESAGYGGLTMEGIAARAQ
Rv1167c|M.tuberculosis_H37Rv -MTVSAPAKANPYRRRGEVLERALYDATLAELESAGYGGLTMEGIAARAQ
MSMEG_5301|M.smegmatis_MC2_155 ---MTTNPRRGRGRRPAQDVRRDVLAAVADLLFTEGMAGFTIDKVAARSG
TH_3283|M.thermoresistible__bu ---MPGSGARSPGRPRDPALDDAIRAAARDVVVEHGYDATTLALIADRAG
: .. : * :: :* :
Mvan_2727|M.vanbaalenii_PYR-1 TSKPVLYRRWPDRRALLRDTLLGIATSAFPTV-DTGGFRGDMLAVLRAWA
Mflv_3683|M.gilvum_PYR-GCK TSKPVLYRRWPDRRALLRDTLMAVASTSFPRP-DTGTFRGDLLAVLRAWA
MAB_1497c|M.abscessus_ATCC_199 ASKTTIYRRWSNKAELIKAALDAHDASFNDEVFDTGGLRTDLIATMGMLR
MMAR_1695|M.marinum_M ASKATVYRRWPSKAELVLAAFIEGVRQVAVAP-NTGSLRDDLVKIGEGIC
MUL_1934|M.ulcerans_Agy99 ASKATVYRRWPSKAELVLAAFIEGVRQVAVAP-NTGSLRDDLVKIGEGIC
MAV_3866|M.avium_104 ASKATVYRRWPSKAELVLAAFIEGVRQVAVPP-NTGTLRGDLLALGETVC
Mb1199c|M.bovis_AF2122/97 TGKAALYRRWAGKRELVLAAVQYALPPVPEPR-ADRSARENLLAVFTANC
Rv1167c|M.tuberculosis_H37Rv TGKAALYRRWAGKRELVLAAVQYALPPVPEPR-ADRSARENLLAVFTANC
MSMEG_5301|M.smegmatis_MC2_155 VSKVTIYKWWPSKGALALDGYFAKVEPRLAFP-DTGDIEADLRSQLHAFL
TH_3283|M.thermoresistible__bu VSVPTIYRRWQHKHELIEEAVLHLDTFELPEP--TGDLEADLGTWVRLFL
.. .:*: * : * . ::
Mvan_2727|M.vanbaalenii_PYR-1 ALFTGDSA-ALMRSAIGAVTADPELAATFRTDVIGARKQEMDAIITRGVQ
Mflv_3683|M.gilvum_PYR-GCK QLFTGDTG-PLMRSVIVAVASDPDLESTFRSDVLGMRKAEMTTLIGRAVE
MAB_1497c|M.abscessus_ATCC_199 RKAQALPP-TLYPDLIRAMEHDETLSDAIRRHLADPGLSPFDAPLSRAVG
MMAR_1695|M.marinum_M GQAHQQAS-TIR-AVLVEVSRHPALSDALQRQFVDQRKALIQQVLQQAVD
MUL_1934|M.ulcerans_Agy99 GQAHQQAS-TIR-AVLVEVSRHPALSDALQRQFVDQRKALIQQVLQQAVD
MAV_3866|M.avium_104 EQVGHHAS-TIR-AVMFEVSRHPALNDALQHQFLDQRRALIEHVLHQAVD
Mb1199c|M.bovis_AF2122/97 EILAGKTA-LPSMEIVSQLLHEPELRAIFINSVWAPRLRIVESILQAGVR
Rv1167c|M.tuberculosis_H37Rv EILAGKTA-LPSMEIVSQLLHEPELRAIFINSVWAPRLRIVESILQAGVR
MSMEG_5301|M.smegmatis_MC2_155 RVIRGTPAGTVIAELIGGAQTDPELKAAFMQRYSGPRRSFAVAAMRRAQE
TH_3283|M.thermoresistible__bu TVAMEPAARAAVPGLMSAYSRNPDDYRRLMTRGELPVRAAIAAMLERAKA
. : . : : .
Mvan_2727|M.vanbaalenii_PYR-1 RGEVRADVPVDLVRELGQSVLWHRLLISGDPIDDEVVTRLVDEVLIPVTR
Mflv_3683|M.gilvum_PYR-GCK RGEVRPDVPVELVRELGQSVLWHRLLITGDPITDELVTQLVDEVLIPVTR
MAB_1497c|M.abscessus_ATCC_199 RGEAGVDVDRQLIHDVAEAMLTHRLTLGG-PLDDAFIGRLVDDVLLVLIR
MMAR_1695|M.marinum_M RGEITQAAITDELWDLLPGYLIFRSIIPNRPPTPHTVQLLVDDFIMPGLT
MUL_1934|M.ulcerans_Agy99 RGEITQAAITDELWDLLPGYLIFRSIIPNRPPTPHTVQLLVDDFIMPGLT
MAV_3866|M.avium_104 RGEISADAISDELWDLLPGYLIFRSIVPTRPPSRRTVQALVDGFLIPGLT
Mb1199c|M.bovis_AF2122/97 SGEIDPATLTPMTARIGPALIHQHVLFTGSPPDREQLTRIIDAMILTTGE
Rv1167c|M.tuberculosis_H37Rv SGEIDPATLTPMTARIGPALIHQHVLFTGSPPDREQLTRIIDAMILTTGE
MSMEG_5301|M.smegmatis_MC2_155 RGQLAAHVDPETVIDQLWGACYNRLLVPDQPLSEQFVDALLDNLFRGIGA
TH_3283|M.thermoresistible__bu AGQAAPDCDPDAVFELIRGATFLRALTHSDEDAEAFCTRITEAVLRAVRS
*: . : : : .:
Mvan_2727|M.vanbaalenii_PYR-1 PYYEV
Mflv_3683|M.gilvum_PYR-GCK PYYDQ
MAB_1497c|M.abscessus_ATCC_199 PGAR-
MMAR_1695|M.marinum_M QATG-
MUL_1934|M.ulcerans_Agy99 QATG-
MAV_3866|M.avium_104 AR---
Mb1199c|M.bovis_AF2122/97 RRES-
Rv1167c|M.tuberculosis_H37Rv RRES-
MSMEG_5301|M.smegmatis_MC2_155 -----
TH_3283|M.thermoresistible__bu -----