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NGTRPRQPRRGRRPTEEVREEVLQAAGELLFTEGMGGFTIDKVAALSGASKMTIYKWWPSKGALALDGYF RKVEPDLNFPDSGEIERDLRAQMRAFLGVIRDTAAGAIIGELIGQAQVDPELKAAFLQRYSGPRRALAVA AIRRAQERGQLRANVDPEVMVDQLWGACYHRLLVPDQPLTAGFVDALLDNLFKGIGA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4749c | - | - | 100% (198) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3462c | - | 5e-27 | 35.68% (185) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0989 | - | 4e-16 | 32.43% (185) | putative HTH-type transcriptional regulator TetR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3192c | - | 7e-15 | 27.75% (191) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1535 | - | 2e-25 | 32.80% (186) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3167c | - | 7e-15 | 27.75% (191) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_01070 | - | 3e-05 | 33.33% (81) | putative TetR-family transcriptional regulator |
| M. marinum M | MMAR_0340 | - | 3e-17 | 32.65% (196) | TetR family transcriptional regulator |
| M. avium 104 | MAV_5165 | - | 4e-19 | 32.47% (194) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_5301 | - | 4e-82 | 75.38% (195) | transcriptional regulator |
| M. thermoresistible (build 8) | TH_4110 | - | 2e-20 | 31.46% (178) | PUTATIVE putative transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_4780 | - | 7e-17 | 32.65% (196) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5223 | - | 2e-27 | 33.87% (186) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_4749c|M.abscessus_ATCC_199 ----MNGTRPRQP------RRGRRPTEEVREEVLQAAGELLFTEGMGGFT
MSMEG_5301|M.smegmatis_MC2_155 ----MT-TNPRR-------GRGRRPAQDVRRDVLAAVADLLFTEGMAGFT
Mb3192c|M.bovis_AF2122/97 -------MKADLPSLDKAPGAGRPRDPRIDSAILSATAELLVQIGYSNLS
Rv3167c|M.tuberculosis_H37Rv -------MKADLPSLDKAPGAGRPRDPRIDSAILSATAELLVQIGYSNLS
MMAR_0340|M.marinum_M -------MVADF---------GRPRDPRIDGAVLRATVELLAETGYAGLL
MUL_4780|M.ulcerans_Agy99 -------MVADF---------GRPRDPRIDGAVLRATVELLAETGYAGLL
MAV_5165|M.avium_104 ---------MDF---------GRPRDPRIDAAVLRATVELLAETGYPGLL
Mflv_1535|M.gilvum_PYR-GCK -------MASRR---------GRPRSEAVRSAVLTAAAELALAGGPAAAS
Mvan_5223|M.vanbaalenii_PYR-1 --MVEAGSAARR---------GRPRSEAARSAVLTAAAELALEGGPAAAT
TH_4110|M.thermoresistible__bu ------VTATDAAATGRAAARGRPRDPALDSAILDAALEIFVEQGISALS
MLBr_01070|M.leprae_Br4923 MIVVGNFTQSNYVPASRGRRSSQLSGDDREQAILAVAERLLAERPLGDFS
.: :* .. :
MAB_4749c|M.abscessus_ATCC_199 IDKVAALSGASKMTIYKWWPSKGALALDGYFRK-VEPDLNFPDSGEIERD
MSMEG_5301|M.smegmatis_MC2_155 IDKVAARSGVSKVTIYKWWPSKGALALDGYFAK-VEPRLAFPDTGDIEAD
Mb3192c|M.bovis_AF2122/97 LAAVAERAGTTKSALYRRWSSKAELVHEAAFPA-APTALQAAAG-DIAAD
Rv3167c|M.tuberculosis_H37Rv LAAVAERAGTTKSALYRRWSSKAELVHEAAFPA-APTALQAAAG-DIAAD
MMAR_0340|M.marinum_M VSAIAKRAGTSKPAIYRRWPSKAHLVHEAVFPI-DAATAVPDTG-SPVDD
MUL_4780|M.ulcerans_Agy99 VSAIAKRAGTSKPAIYRRWPSKAHLVHEAVFPI-DAATAVPDTG-SPVDD
MAV_5165|M.avium_104 VSAIAQRAGTSKPAIYRRWPSKAHLVHEAVFPV-GADTAIPDTG-STADD
Mflv_1535|M.gilvum_PYR-GCK VEAIARRAEVSRTTIYKWWPSAPAIVLEGLLDS-VRDSITRPPGSTSVEA
Mvan_5223|M.vanbaalenii_PYR-1 VEAIAKRAHVSRTTIYKWWPSAASIVLEGLLDA-VRASITRPSGSTSVQA
TH_4110|M.thermoresistible__bu IEQVARRAGVGKPTIYRRWSDKEQLVADAIEHR-VSAELAWPTPAEASVS
MLBr_01070|M.leprae_Br4923 VDELAKGAGISRPTFYFYFPSKNAVLLSLLDDLNMKSRSAVEALAEQLPA
: :* : : ::* :.. : .
MAB_4749c|M.abscessus_ATCC_199 -----LRAQMRAFLGVIRDTAAGAIIGELIGQAQVDPELKAAFLQRYSGP
MSMEG_5301|M.smegmatis_MC2_155 -----LRSQLHAFLRVIRGTPAGTVIAELIGGAQTDPELKAAFMQRYSGP
Mb3192c|M.bovis_AF2122/97 -----IRMMIAATRDVFTTPVVRAALPGLVADMTADAELNARVLARFADL
Rv3167c|M.tuberculosis_H37Rv -----IRMMIAATRDVFTTPVVRAALPGLVADMTADAELNARVLARFADL
MMAR_0340|M.marinum_M -----LREMVRRTTAVLSTPAAKAALPGLIGEMAADPTLHSALLVRFGEI
MUL_4780|M.ulcerans_Agy99 -----LREMVRRTTAVLSTPAAKAAQPGLIGEMAADPTLHSALLVRFGEI
MAV_5165|M.avium_104 -----LREMVRRTMVFLTTPAAKAALPGLIGEMAADPSLHSALLERFAGA
Mflv_1535|M.gilvum_PYR-GCK -----VVHHVCALNAILVDPTVGPLLRNVIAASASDPAIQQALCDQWIAP
Mvan_5223|M.vanbaalenii_PYR-1 -----LVHHVSSLNAILADPAVGPLLRNVIAASTSDPAIERAVLDQWIAP
TH_4110|M.thermoresistible__bu DPYELVRRNISAAARTAADPAFRGLIAAIYGSAVTHPALLRTYWEHYILP
MLBr_01070|M.leprae_Br4923 DPAAVWRSAITAFFEVCGTHRAVAVAGAAAKATSPEVRRLWSTVMQQWID
: . :
MAB_4749c|M.abscessus_ATCC_199 RRALAVAAIRRAQERGQLRANVDPEVMVDQLWGACYHRLLVPDQPLTA--
MSMEG_5301|M.smegmatis_MC2_155 RRSFAVAAMRRAQERGQLAAHVDPETVIDQLWGACYNRLLVPDQPLSE--
Mb3192c|M.bovis_AF2122/97 FAA-VRMRLREAVDRGEAHPDVDPDRLIELIGGATMLRMLLYPDDMLD--
Rv3167c|M.tuberculosis_H37Rv FAA-VRMRLREAVDRGEAHPDVDPDRLIELIGGATMLRMLLYPDDMLD--
MMAR_0340|M.marinum_M FGHGLTTWLDNAAARGQVRADVTAPELAEAIAGIVLIGLLTRPGELEPGV
MUL_4780|M.ulcerans_Agy99 FGHGLTTWLDNAAARGQVRADVTAPELAEAIAGIVLIGLLTRPGELEPGV
MAV_5165|M.avium_104 IGGGLADWLAAAAARGEARPDVTAAELAETIAGVTLVALLTRPTELD---
Mflv_1535|M.gilvum_PYR-GCK RRAAVAATVRDAVEGGELRDDVDVEVVVDAVVSPPYYRLVLGMPPLDD--
Mvan_5223|M.vanbaalenii_PYR-1 RRAAVAVTLREAVDRGELPGDVDIEVAVDALVSPPYYRLVLGMPPLAA--
TH_4110|M.thermoresistible__bu RRTAAIALLRRARDLGTVAADADLDVLVDMLAGAVTYRVLQPEPPSAR--
MLBr_01070|M.leprae_Br4923 YNTAAIQAERKCGVAPDTIPAEDLAVALQLMTERVMAATFSDEKPLIPD-
. : : .
MAB_4749c|M.abscessus_ATCC_199 --GFVDALLDNLFKGIGA--------
MSMEG_5301|M.smegmatis_MC2_155 --QFVDALLDNLFRGIGA--------
Mb3192c|M.bovis_AF2122/97 -DAWVDQTTAIVVRGVHRAAPGGSVV
Rv3167c|M.tuberculosis_H37Rv -DAWVDQTTAIVVRGVHRAAPGGSVV
MMAR_0340|M.marinum_M GDAWIDRTTTLLLKGIRKGTPQ----
MUL_4780|M.ulcerans_Agy99 GDAWIDRTTTLLLKGIRKGTPQ----
MAV_5165|M.avium_104 -DAWVDRTTRLLLKGISA--------
Mflv_1535|M.gilvum_PYR-GCK --RAIDGLVRAVWRGYRH--------
Mvan_5223|M.vanbaalenii_PYR-1 --EAVDRLVETVWSGCRH--------
TH_4110|M.thermoresistible__bu ---QLRCYLEVAYRQVGLLP------
MLBr_01070|M.leprae_Br4923 -KKVIDTLVHIWLASIYGS-------
: