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VASRRGRPRSEAVRSAVLTAAAELALAGGPAAASVEAIARRAEVSRTTIYKWWPSAPAIVLEGLLDSVRD SITRPPGSTSVEAVVHHVCALNAILVDPTVGPLLRNVIAASASDPAIQQALCDQWIAPRRAAVAATVRDA VEGGELRDDVDVEVVVDAVVSPPYYRLVLGMPPLDDRAIDGLVRAVWRGYRH
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1535 | - | - | 100% (192) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_3683 | - | 3e-19 | 32.79% (183) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_3225 | - | 4e-19 | 30.57% (193) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3192c | - | 7e-14 | 27.03% (185) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3167c | - | 7e-14 | 27.03% (185) | TetR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4749c | - | 2e-25 | 32.80% (186) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0340 | - | 7e-12 | 30.97% (155) | TetR family transcriptional regulator |
| M. avium 104 | MAV_5165 | - | 6e-15 | 28.80% (184) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_5301 | - | 9e-24 | 31.35% (185) | transcriptional regulator |
| M. thermoresistible (build 8) | TH_4110 | - | 3e-21 | 32.77% (177) | PUTATIVE putative transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_4780 | - | 3e-11 | 30.32% (155) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5223 | - | 9e-82 | 78.53% (191) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1535|M.gilvum_PYR-GCK ----------MASRRGRPRSEAVRSAVLTAAAELALAGGPAAASVEAIAR
Mvan_5223|M.vanbaalenii_PYR-1 -----MVEAGSAARRGRPRSEAARSAVLTAAAELALEGGPAAATVEAIAK
MAB_4749c|M.abscessus_ATCC_199 ----MNGTRPRQPRRGRRPTEEVREEVLQAAGELLFTEGMGGFTIDKVAA
MSMEG_5301|M.smegmatis_MC2_155 ----MT-TNPRR-GRGRRPAQDVRRDVLAAVADLLFTEGMAGFTIDKVAA
Mb3192c|M.bovis_AF2122/97 -MKADLPSLDKAPGAGRPRDPRIDSAILSATAELLVQIGYSNLSLAAVAE
Rv3167c|M.tuberculosis_H37Rv -MKADLPSLDKAPGAGRPRDPRIDSAILSATAELLVQIGYSNLSLAAVAE
MMAR_0340|M.marinum_M -MVADF---------GRPRDPRIDGAVLRATVELLAETGYAGLLVSAIAK
MUL_4780|M.ulcerans_Agy99 -MVADF---------GRPRDPRIDGAVLRATVELLAETGYAGLLVSAIAK
MAV_5165|M.avium_104 ---MDF---------GRPRDPRIDAAVLRATVELLAETGYPGLLVSAIAQ
TH_4110|M.thermoresistible__bu VTATDAAATGRAAARGRPRDPALDSAILDAALEIFVEQGISALSIEQVAR
** :* *. :: * : :*
Mflv_1535|M.gilvum_PYR-GCK RAEVSRTTIYKWWPSAPAIVLEGLLDSVRDSITRPP-----GSTSVEAVV
Mvan_5223|M.vanbaalenii_PYR-1 RAHVSRTTIYKWWPSAASIVLEGLLDAVRASITRPS-----GSTSVQALV
MAB_4749c|M.abscessus_ATCC_199 LSGASKMTIYKWWPSKGALALDGYFRKVEPDLNFPD-----SGEIERDLR
MSMEG_5301|M.smegmatis_MC2_155 RSGVSKVTIYKWWPSKGALALDGYFAKVEPRLAFPD-----TGDIEADLR
Mb3192c|M.bovis_AF2122/97 RAGTTKSALYRRWSSKAELVHEAAFP-AAPTALQAA-----AGDIAADIR
Rv3167c|M.tuberculosis_H37Rv RAGTTKSALYRRWSSKAELVHEAAFP-AAPTALQAA-----AGDIAADIR
MMAR_0340|M.marinum_M RAGTSKPAIYRRWPSKAHLVHEAVFP-IDAATAVPD-----TGSPVDDLR
MUL_4780|M.ulcerans_Agy99 RAGTSKPAIYRRWPSKAHLVHEAVFP-IDAATAVPD-----TGSPVDDLR
MAV_5165|M.avium_104 RAGTSKPAIYRRWPSKAHLVHEAVFP-VGADTAIPD-----TGSTADDLR
TH_4110|M.thermoresistible__bu RAGVGKPTIYRRWSDKEQLVADAIEHRVSAELAWPTPAEASVSDPYELVR
: . : ::*: *.. :. :. . . :
Mflv_1535|M.gilvum_PYR-GCK HHVCALNAILVDPTVGPLLRNVIAASASDPAIQQALCDQWIAPRRAAVAA
Mvan_5223|M.vanbaalenii_PYR-1 HHVSSLNAILADPAVGPLLRNVIAASTSDPAIERAVLDQWIAPRRAAVAV
MAB_4749c|M.abscessus_ATCC_199 AQMRAFLGVIRDTAAGAIIGELIGQAQVDPELKAAFLQRYSGPRRALAVA
MSMEG_5301|M.smegmatis_MC2_155 SQLHAFLRVIRGTPAGTVIAELIGGAQTDPELKAAFMQRYSGPRRSFAVA
Mb3192c|M.bovis_AF2122/97 MMIAATRDVFTTPVVRAALPGLVADMTADAELNARVLARFADLFAA-VRM
Rv3167c|M.tuberculosis_H37Rv MMIAATRDVFTTPVVRAALPGLVADMTADAELNARVLARFADLFAA-VRM
MMAR_0340|M.marinum_M EMVRRTTAVLSTPAAKAALPGLIGEMAADPTLHSALLVRFGEIFGHGLTT
MUL_4780|M.ulcerans_Agy99 EMVRRTTAVLSTPAAKAAQPGLIGEMAADPTLHSALLVRFGEIFGHGLTT
MAV_5165|M.avium_104 EMVRRTMVFLTTPAAKAALPGLIGEMAADPSLHSALLERFAGAIGGGLAD
TH_4110|M.thermoresistible__bu RNISAAARTAADPAFRGLIAAIYGSAVTHPALLRTYWEHYILPRRTAAIA
: . : . .. : ::
Mflv_1535|M.gilvum_PYR-GCK TVRDAVEGGELRDDVDVEVVVDAVVSPPYYRLVLGMPPLD----DRAIDG
Mvan_5223|M.vanbaalenii_PYR-1 TLREAVDRGELPGDVDIEVAVDALVSPPYYRLVLGMPPLA----AEAVDR
MAB_4749c|M.abscessus_ATCC_199 AIRRAQERGQLRANVDPEVMVDQLWGACYHRLLVPDQPLT----AGFVDA
MSMEG_5301|M.smegmatis_MC2_155 AMRRAQERGQLAAHVDPETVIDQLWGACYNRLLVPDQPLS----EQFVDA
Mb3192c|M.bovis_AF2122/97 RLREAVDRGEAHPDVDPDRLIELIGGATMLRMLLYPDDMLD---DAWVDQ
Rv3167c|M.tuberculosis_H37Rv RLREAVDRGEAHPDVDPDRLIELIGGATMLRMLLYPDDMLD---DAWVDQ
MMAR_0340|M.marinum_M WLDNAAARGQVRADVTAPELAEAIAGIVLIGLLTRPGELEPGVGDAWIDR
MUL_4780|M.ulcerans_Agy99 WLDNAAARGQVRADVTAPELAEAIAGIVLIGLLTRPGELEPGVGDAWIDR
MAV_5165|M.avium_104 WLAAAAARGEARPDVTAAELAETIAGVTLVALLTRPTELD----DAWVDR
TH_4110|M.thermoresistible__bu LLRRARDLGTVAADADLDVLVDMLAGAVTYRVLQPEPPSAR-----QLRC
: * * .. : : . :: :
Mflv_1535|M.gilvum_PYR-GCK LVRAVWRGYRH--------
Mvan_5223|M.vanbaalenii_PYR-1 LVETVWSGCRH--------
MAB_4749c|M.abscessus_ATCC_199 LLDNLFKGIGA--------
MSMEG_5301|M.smegmatis_MC2_155 LLDNLFRGIGA--------
Mb3192c|M.bovis_AF2122/97 TTAIVVRGVHRAAPGGSVV
Rv3167c|M.tuberculosis_H37Rv TTAIVVRGVHRAAPGGSVV
MMAR_0340|M.marinum_M TTTLLLKGIRKGTPQ----
MUL_4780|M.ulcerans_Agy99 TTTLLLKGIRKGTPQ----
MAV_5165|M.avium_104 TTRLLLKGISA--------
TH_4110|M.thermoresistible__bu YLEVAYRQVGLLP------