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VSRIRALALRDALLDEGSFVSWDGPPLAVPTSAEYRRELAEAEAATGLDESVLTGEGRVFGRRVALIACE FDFLAGSIGVAAAERIIAAVQKATAERLPLLASPSSGGTRMQEGTVAFLQMVKIAAAVELHKKAHLPYLV YLRHPTTGGVFASWGSLGHVTAAEPGALIGFLGPRVYEHLYGEPFPAGIQTAENLHRHGVVDAVIPPGIL RATLDRALRVVSDAPDVPPAAPDAEPLPDVPAWESVEISRRPDRPGVSALLRYGTTDRVLLSGTGQGEAA TTLLALARFGGQPAVVLGQQRVVGGLVGPAALREARRGMALAAGLKLPLVLVIDTAGPALSTEAEEGGLA GEIARCLAELVTLDTPTVSVLLGQGSGGPALAMVPADRVLAALHGWLAPLPPEGASAIVFRDVDHAPELA AAQGIRSADLLRNGIVDAIVPEHPDAADEPQAFTQRLSATIAVELHRLRTVPDEQRLAARLERYRRIGLP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4993 | - | - | 100% (490) | carboxyl transferase |
| M. vanbaalenii PYR-1 | Mvan_1677 | - | 1e-14 | 24.52% (420) | carboxyl transferase |
| M. vanbaalenii PYR-1 | Mvan_5639 | - | 5e-14 | 23.67% (469) | carboxyl transferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0928c | accD3 | 0.0 | 78.50% (493) | putative acetyl-coenzyme A carboxylase carboxyl transferase |
| M. gilvum PYR-GCK | Mflv_1754 | - | 0.0 | 87.53% (489) | carboxyl transferase |
| M. tuberculosis H37Rv | Rv0904c | accD3 | 0.0 | 78.50% (493) | putative acetyl-coenzyme A carboxylase carboxyl transferase |
| M. leprae Br4923 | MLBr_00102 | accD4 | 3e-14 | 22.20% (428) | putative acyl CoA carboxylase beta subunit |
| M. abscessus ATCC 19977 | MAB_0181 | - | 1e-14 | 24.17% (422) | propionyl-CoA carboxylase, beta subunit (PccB) |
| M. marinum M | MMAR_4626 | accD3 | 0.0 | 79.59% (490) | acetyl-coenzyme A carboxylase carboxyl transferase (subunit |
| M. avium 104 | MAV_2190 | - | 1e-14 | 23.77% (408) | propionyl-CoA carboxylase beta chain |
| M. smegmatis MC2 155 | MSMEG_5642 | - | 0.0 | 83.64% (489) | acetyl-coenzyme a carboxylase carboxyl transferase |
| M. thermoresistible (build 8) | TH_0091 | accD3 | 0.0 | 79.84% (491) | PUTATIVE ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE |
| M. ulcerans Agy99 | MUL_0237 | accD3 | 0.0 | 78.78% (490) | acetyl-coenzyme a carboxylase carboxyl transferase (subunit |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0928c|M.bovis_AF2122/97 ---------------MSRITTDQLRHAVLDRGSFVSWDSEPLAVPVADSY
Rv0904c|M.tuberculosis_H37Rv ---------------MSRITTDQLRHAVLDRGSFVSWDSEPLAVPVADSY
MMAR_4626|M.marinum_M ---------------MSRITTDQLRDAVLDEGSFISWDTPPLEVPISESY
MUL_0237|M.ulcerans_Agy99 ---------------MSRITTDQLRDAVLDEDSFISWDTPPLEVPISESY
Mvan_4993|M.vanbaalenii_PYR-1 ---------------MSRIRALALRDALLDEGSFVSWDGPPLAVPTSAEY
Mflv_1754|M.gilvum_PYR-GCK ---------------MSRIGALALRDAVLDEGSFLSWDRPPIPVVTSAEY
MSMEG_5642|M.smegmatis_MC2_155 ---------------MSRIGALALRDAVLDEGSFRSWDTAPLDVGADDEY
TH_0091|M.thermoresistible__bu ---------------MSRIGAVQFVETVLDTGSFVSWDDPPLAIPADEDY
MLBr_00102|M.leprae_Br4923 MIMKSTAEKLAELRVRLELANEPGGEKAAAKRDKKNIPSARARIYALVDP
MAB_0181|M.abscessus_ATCC_1997 MPPHTTAEKLADLRERIALTREPGDAKAIARRDKKGIPSARARIDALLDK
MAV_2190|M.avium_104 ----------------MTITAPETVGESLDPRD------PLLRLSNFFDD
: . : .
Mb0928c|M.bovis_AF2122/97 ARELAAARAATGADE-------SVQTGEGRVFGRRVAVVACEFDFLGGSI
Rv0904c|M.tuberculosis_H37Rv ARELAAARAATGADE-------SVQTGEGRVFGRRVAVVACEFDFLGGSI
MMAR_4626|M.marinum_M ARDLADARAATGRDE-------SVLTGEGRVLGRRVAVVVCEFDFLAGSI
MUL_0237|M.ulcerans_Agy99 ARDLADVRAATGRDE-------SVLTGEGRVLGRRVAVVACEFDFLAGSI
Mvan_4993|M.vanbaalenii_PYR-1 RRELAEAEAATGLDE-------SVLTGEGRVFGRRVALIACEFDFLAGSI
Mflv_1754|M.gilvum_PYR-GCK RAELAAAADATGLDE-------SVVTGEGRVFGRRVALIACEFDFLAGSI
MSMEG_5642|M.smegmatis_MC2_155 RRELAEASAKTGLDE-------SVLTGEGTVFGRRVAVVACEFDFLAGSI
TH_0091|M.thermoresistible__bu RRELTDAAAVTGLDE-------AVLTGEGTIFGRRVALVACEFDFLAGSI
MLBr_00102|M.leprae_Br4923 GTFLEIGALTRTPGDPNALYGDGVVTGHGLINGRQVGVFSHDQTVFGGTV
MAB_0181|M.abscessus_ATCC_1997 GSFLELDAFARTPGDANAPYTDGVVTGLGRIDGRPVAVFSHDQTVYQGSV
MAV_2190|M.avium_104 GSVALLHERDRS----------GVLAAAGTVNGVRTIAFCTDGTVMGGAM
.* :. * : * . . : . *::
Mb0928c|M.bovis_AF2122/97 GVAAAERITAAVERATAERLPLLASPSSGGTRMQEGTVAFLQMVKIAAAI
Rv0904c|M.tuberculosis_H37Rv GVAAAERITAAVERATAERLPLLASPSSGGTRMQEGTVAFLQMVKIAAAI
MMAR_4626|M.marinum_M GVAAAERITAAVERATRQRLPLLASPSSGGTRMQEGTVAFLQMVKIAAAV
MUL_0237|M.ulcerans_Agy99 GVAAAERITAAMERATSQRLPLLASPSSGGTRMQEGTVAFLQMVKIAAAV
Mvan_4993|M.vanbaalenii_PYR-1 GVAAAERIIAAVQKATAERLPLLASPSSGGTRMQEGTVAFLQMVKIAAAV
Mflv_1754|M.gilvum_PYR-GCK GVAAAERITAAVQRATAEGLPLLASPSSGGTRMQEGTVAFLQMVKIAAAV
MSMEG_5642|M.smegmatis_MC2_155 GVAAAERITAAVQRATAERLPLLASPSSGGTRMQEGTVAFLQMVKIAAAV
TH_0091|M.thermoresistible__bu GVAAAERIVAAVQRATAERLPLVASPSSGGTRMQEGTVAFLQMVKIAAAV
MLBr_00102|M.leprae_Br4923 GEMFGRKVARLMEWCAMAGCPIVGINDSGGARIQDAVTSLAWYAELGRRH
MAB_0181|M.abscessus_ATCC_1997 GEMFGRKVAKLMEWAATNGCPVIGINDSAGARIQDTATSLAWYAELGRRH
MAV_2190|M.avium_104 GIEGCSHIVDAYDTAIEEQSPIVGIWHSGGARLAEGVKALHAVGLVFEAM
* :: : . *::. *.*:*: : . :: :
Mb0928c|M.bovis_AF2122/97 QLHNQARLPYLVYLRHPTTGGVFASWGSLGHLTVAEPGALIGFLGPRVYE
Rv0904c|M.tuberculosis_H37Rv QLHNQARLPYLVYLRHPTTGGVFASWGSLGHLTVAEPGALIGFLGPRVYE
MMAR_4626|M.marinum_M RLHKQAHLPYLVYLRHPTTGGVFASWGSLGHVTVAEPGALIGFLGPRVYE
MUL_0237|M.ulcerans_Agy99 RLHKQAHLPYLVYLRHPTTGGVFASWGSLGHVTVAEPGALIGFLGPRVYE
Mvan_4993|M.vanbaalenii_PYR-1 ELHKKAHLPYLVYLRHPTTGGVFASWGSLGHVTAAEPGALIGFLGPRVYE
Mflv_1754|M.gilvum_PYR-GCK ELHKKGNLPYLVYLRHPTTGGVFASWGSLGHVTAAEPDALIGFLGPRVYE
MSMEG_5642|M.smegmatis_MC2_155 ELHKQAHLPYLVYLRHPTTGGVFASWGSLGHVTAAEPGALIGFLGPRVYE
TH_0091|M.thermoresistible__bu QLHKLAHLSYLVYLRHPTTGGVFASWGSLGHITIAEPNALIGFLGPRVYQ
MLBr_00102|M.leprae_Br4923 ELLS-GIVPQISIVLGKCAGGAVYSPIQTDLVVAVRGQGYMFVTGPDVIK
MAB_0181|M.abscessus_ATCC_1997 ELLR-GTVPEISIILGKCAGGAVYSPIQTDLLVAVRDQGYMFITGPDVIK
MAV_2190|M.avium_104 IRAS-GYIPQISVVVGFAAGGAAYGPALTDVVVMAP-ESRVFVTGPDVVR
. :. : : :**. . . :. . . : . ** * .
Mb0928c|M.bovis_AF2122/97 LLYGDPFPSGVQTAENLRRHG--IIDGVVALDRLRPMLDRALTVLIDAPE
Rv0904c|M.tuberculosis_H37Rv LLYGDPFPSGVQTAENLRRHG--IIDGVVALDRLRPMLDRALTVLIDAPE
MMAR_4626|M.marinum_M LLYDEPFPAGIQTAENLQRHG--VIDGVVTLDELRRTLDRALTVLTDAPA
MUL_0237|M.ulcerans_Agy99 LLYDEPFPAGVQTAENLQRHG--VIDGVVTLDELRRTLDRALTVLTDAPA
Mvan_4993|M.vanbaalenii_PYR-1 HLYGEPFPAGIQTAENLHRHG--VVDAVIPPGILRATLDRALRVVSDAPD
Mflv_1754|M.gilvum_PYR-GCK HLYGERFPSGVQTSENLQRHG--VIDAVVPLEVLRATVDRTLKVVADAPG
MSMEG_5642|M.smegmatis_MC2_155 HLYGEPFPSGVQTAENLHAHG--VIDGVVPLALLRETLDRTLRVVADPPG
TH_0091|M.thermoresistible__bu HLYGEPFPPGVQTAENLHRHG--VIDSVVPLPRLRSELDRALRVLVDEPG
MLBr_00102|M.leprae_Br4923 DVTGEEVSLDELGGVDSQAKY-GNIHQVVESEAAAFGYVRDFLSFLPPN-
MAB_0181|M.abscessus_ATCC_1997 DVTGEDVSFDELGGADVQAQR-GNIHKVVEDEAAAFQYVRDYLSFLPSN-
MAV_2190|M.avium_104 SVTGEDVDMASLGGPETHHKKSGVCHIVADDELDAYERGRRLVGLFCQQG
: .: . . : : : . * * .
Mb0928c|M.bovis_AF2122/97 PLPAPQTPA--PVPDVPTWDSVVASRRPDRP----GVRQLLRHGATDRVL
Rv0904c|M.tuberculosis_H37Rv PLPAPQTPA--PVPDVPTWDSVVASRRPDRP----GVRQLLRHGATDRVL
MMAR_4626|M.marinum_M PAPAAPAPT--AIPDVPAWTSVLASRRPDRP----GVEHLLRYGATDRVL
MUL_0237|M.ulcerans_Agy99 PAPAAPAPP--AIPDVAAWTSVLASRRPDRP----GVEHLLRYGATDRVL
Mvan_4993|M.vanbaalenii_PYR-1 VPPAAPDAE--PLPDVPAWESVEISRRPDRP----GVSALLRYGTTDRVL
Mflv_1754|M.gilvum_PYR-GCK PPPAAPEPE--VLPDIPAWDSVEISRRPDRP----GVSFLLRHGATERVL
MSMEG_5642|M.smegmatis_MC2_155 PAPAVIETE--DLPDVPAWDSVIASRRPDRP----GVGFLLRHGATDQVL
TH_0091|M.thermoresistible__bu TPPAPPDVDT-SQPDVPAWDSVIASRRPDRP----GVGYLLRHGATDTVL
MLBr_00102|M.leprae_Br4923 CFDKAPIVNPGLEPEIMAHDLELDSIVPDSDNTAYDMREVLLRIFDDGH-
MAB_0181|M.abscessus_ATCC_1997 TFDYPPIVNPGLEPEITEDDLYLDTFIPDSDNQGYDMMEILLRIFDDGD-
MAV_2190|M.avium_104 HFDRT---------KAEAGDTDIHALLPESARRAYDVRPIVTAILDDETP
. : *: .: :: :
Mb0928c|M.bovis_AF2122/97 LSGTDQGEAATTLLALARFGGQPTVVLGQQRAVGGGGSTVGPAALREARR
Rv0904c|M.tuberculosis_H37Rv LSGTDQGEAATTLLALARFGGQPTVVLGQQRAVGGGGSTVGPAALREARR
MMAR_4626|M.marinum_M LSGTGYGDAATTLLALARMAGQPMVVLGQQ-GIGGG--IIGPASLREARR
MUL_0237|M.ulcerans_Agy99 LSGTGYGDAATTLLALARMAGQPMVVLGQQ-GIGGG--IIGPASLREARR
Mvan_4993|M.vanbaalenii_PYR-1 LSGTGQGEAATTLLALARFGGQPAVVLGQQRVVGGL---VGPAALREARR
Mflv_1754|M.gilvum_PYR-GCK LSGTGQGESATMMLALARFGNQPAVVLGQQRVVGGL---VGPAALREARR
MSMEG_5642|M.smegmatis_MC2_155 LSGTERGEAATTLLALARFGGQPAVVLGQRRIVGGL---VGPGALREARR
TH_0091|M.thermoresistible__bu LSGSGGGEAATTLLALARFGGQPAVVLGQQRVIGAM---VGPAALREARR
MLBr_00102|M.leprae_Br4923 FLDVAAQAGQAIITGYARVDGRTVGVVANQPMHLSG--AIDNEASDKAAR
MAB_0181|M.abscessus_ATCC_1997 IFEISEQRGPAMITAFARVDGHPVGVIANQPLQMAG--AVDTDASDKAAS
MAV_2190|M.avium_104 FDEFQANWAPSMVIGLGRLSGRTVGVLANNPLRLGG--CLNSESAEKAAR
: . : : . .*. .:. *:.:. . :. : :*
Mb0928c|M.bovis_AF2122/97 GMALAAELCLPLVLVIDAAGPALSAAAEQGGLAGQIAHCLAELVTLDTPT
Rv0904c|M.tuberculosis_H37Rv GMALAAELCLPLVLVIDAAGPALSAAAEQGGLAGQIAHCLAELVTLDTPT
MMAR_4626|M.marinum_M GMALAAELRLPLVLVIDTAGPALSADAEQGGLAGQIAQCLAELVTLGTPT
MUL_0237|M.ulcerans_Agy99 GMALAAELRLPLVLVIDTAGPALSADAEQGGLAGQIAQCLAELVTLGTPT
Mvan_4993|M.vanbaalenii_PYR-1 GMALAAGLKLPLVLVIDTAGPALSTEAEEGGLAGEIARCLAELVTLDTPT
Mflv_1754|M.gilvum_PYR-GCK GMALAASLKLPLVLVIDTAGPALSTEAEEGGLAGEIARCLAELVTLDTPT
MSMEG_5642|M.smegmatis_MC2_155 GMALAAGLQLPLVLVIDTAGPALSTEAEQGGLAGEIARCLAELVTLDTPT
TH_0091|M.thermoresistible__bu GMALAADLQLPLVLVIDTAGPALTAEAEQGGLASEIAHCLAELVTLDTAT
MLBr_00102|M.leprae_Br4923 FIRFCDAFNIPLVFVVDTPGFLPGVEQEKNGIIKRGGRFLYAVVEADVPK
MAB_0181|M.abscessus_ATCC_1997 FIRFCDAYNLPLVFVVDTPGALPGVSEEKNGIIKKGGRFFNAVVEADVPK
MAV_2190|M.avium_104 FVRLCDAFGIPLVVIVDVPGYLPGVDQEWGGVVRRGAKLLHAFGEATVPR
: :. :***.::*..* . * .*: . .: : . ..
Mb0928c|M.bovis_AF2122/97 VSILLGQGSGGPALAMLP----ADRVLAALHGWLAPLPPEGASAIVFRDT
Rv0904c|M.tuberculosis_H37Rv VSILLGQGSGGPALAMLP----ADRVLAALHGWLAPLPPEGASAIVFRDT
MMAR_4626|M.marinum_M VSVLLGQGSGGPALAMVP----ADRVLAAQHGWLAPLPPEGASAIVFRDT
MUL_0237|M.ulcerans_Agy99 VSVLLGQGSGGPALAMVP----ADRVLAAQHGWLAPLPPEGASAIVFRDT
Mvan_4993|M.vanbaalenii_PYR-1 VSVLLGQGSGGPALAMVP----ADRVLAALHGWLAPLPPEGASAIVFRDV
Mflv_1754|M.gilvum_PYR-GCK VSVLLGQGSGGPALAMVP----ADRVLAALHGWLAPLPPEGASAIVFRDV
MSMEG_5642|M.smegmatis_MC2_155 VSVLMGQGSGGPALAMVP----ADRVLAASNGWLAPLPPEGASAIVYRDT
TH_0091|M.thermoresistible__bu LSVLLGQGSGGPALAMVP----ADRVLAARHGWLAPLPPEGVSAIVHRDL
MLBr_00102|M.leprae_Br4923 VTITIRKSYGGAYAVMGSKQLAADLNFAWPTARIAVIGADGAAQLLMKR-
MAB_0181|M.abscessus_ATCC_1997 VTIITRKAYGGGYAVMGSKQLSADLNYVWPTARIAVIGAEGAAQLLVKR-
MAV_2190|M.avium_104 VTLVTRKTYGGAYIAMNSRSLNATKVFAWPDAEVAVMGAKAAVGILHKKK
::: : ** .* . * . . :* : .... :: :
Mb0928c|M.bovis_AF2122/97 AHAAELAAAQGIRSADLLKSGIVDTIVPEYPDAADEPIEFALRLSNAIAA
Rv0904c|M.tuberculosis_H37Rv AHAAELAAAQGIRSADLLKSGIVDTIVPEYPDAADEPIEFALRLSNAIAA
MMAR_4626|M.marinum_M THAAELAAAQGIRSADLLAAGIVDVIVPELPDAAAEPVEFAQRLSIAIAT
MUL_0237|M.ulcerans_Agy99 THAAELAAAQGIRSADLLAAGIVDVIVPELPDAAAEPVEFAQRLSIAIAT
Mvan_4993|M.vanbaalenii_PYR-1 DHAPELAAAQGIRSADLLRNGIVDAIVPEHPDAADEPQAFTQRLSATIAV
Mflv_1754|M.gilvum_PYR-GCK DHAPELAAAQGIRSVDLLRDGIVDAVVPEHPDAADEPRAFVERLSATIAV
MSMEG_5642|M.smegmatis_MC2_155 EHAPELAAAQGVRAVDLLRHGIVDVVVAEKPDAADEPRAFTARLSTAIAA
TH_0091|M.thermoresistible__bu DHAPELAARQGIRSVDLLRHGIVDAIVDERPDAADEPMEFTARLADSIAV
MLBr_00102|M.leprae_Br4923 FPDPSSPDVQAIR--KTFVDNYNLNMAIPWIAAERGFIDAVVEPHQTRLL
MAB_0181|M.abscessus_ATCC_1997 FPDPTAPEVQKIR--ADFIEGYNKNLATPWIAAERGYIDGVIEPHQTRLL
MAV_2190|M.avium_104 LAAAPEHEREALH--DQLAAEHEKIAGGVDSAIEIGVVDEKIDPAHTRSK
. : :: : :
Mb0928c|M.bovis_AF2122/97 EVHALRKIPAPERLATRLQRYRRIGLPRD-
Rv0904c|M.tuberculosis_H37Rv EVHALRKIPAPERLATRLQRYRRIGLPRD-
MMAR_4626|M.marinum_M EVAALREIPDAQRMTARLARYRSIGLPRDR
MUL_0237|M.ulcerans_Agy99 EVAALREIPDAQRMTARLARYRSIGLPRDR
Mvan_4993|M.vanbaalenii_PYR-1 ELHRLRTVPDEQRLAARLERYRRIGLP---
Mflv_1754|M.gilvum_PYR-GCK ELHRLRFAPEAERSASRLERYRRIGLA---
MSMEG_5642|M.smegmatis_MC2_155 ELHNLRAVPDDERLQTRLQRYRRIGL----
TH_0091|M.thermoresistible__bu ELHRLREMPAESRLETRLARYRRIGLPR--
MLBr_00102|M.leprae_Br4923 LRKSLHLLRDKQQWWRVGRKHGLIPL----
MAB_0181|M.abscessus_ATCC_1997 LRKSLKLLRDKQKHDRMQRKHGLTPI----
MAV_2190|M.avium_104 LTEALAQAPARR------GRHKNIPL----
* :: :