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M. thermoresistible (build 8) TH_0091 (accD3)

annotation: PUTATIVE ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE (SUBUNIT BETA) ACCD3 (ACCASE BETA CHAIN)
coordinates: 173122 - 174600
length: 493

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0091accD3-100% (493)PUTATIVE ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE (SUBUNIT BETA) ACCD3 (ACCASE BETA CHAIN)
M. thermoresistible (build 8)TH_4304-8e-1222.77% (448) PUTATIVE propionyl-CoA carboxylase beta chain
M. thermoresistible (build 8)TH_2343-1e-1125.30% (502) methylmalonyl-CoA carboxyltransferase 12S subunit

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0928caccD30.076.16% (495) putative acetyl-coenzyme A carboxylase carboxyl transferase
M. gilvum PYR-GCKMflv_1754-0.076.94% (490) carboxyl transferase
M. tuberculosis H37RvRv0904caccD30.076.16% (495) putative acetyl-coenzyme A carboxylase carboxyl transferase
M. leprae Br4923MLBr_01657-5e-1122.45% (432) acetyl/propionyl CoA carboxylase beta subunit
M. abscessus ATCC 19977MAB_0181-3e-0922.19% (383) propionyl-CoA carboxylase, beta subunit (PccB)
M. marinum MMMAR_4626accD30.074.80% (492) acetyl-coenzyme A carboxylase carboxyl transferase (subunit
M. avium 104MAV_2190-4e-1223.04% (434) propionyl-CoA carboxylase beta chain
M. smegmatis MC2 155MSMEG_5642-0.080.04% (491) acetyl-coenzyme a carboxylase carboxyl transferase
M. ulcerans Agy99MUL_0237accD30.074.19% (492) acetyl-coenzyme a carboxylase carboxyl transferase (subunit
M. vanbaalenii PYR-1Mvan_4993-0.079.84% (491) carboxyl transferase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1754|M.gilvum_PYR-GCK          ----------------MSRIGALALRDAVLDEG------SFLSWDRPPIP
Mvan_4993|M.vanbaalenii_PYR-1       ----------------MSRIRALALRDALLDEG------SFVSWDGPPLA
MSMEG_5642|M.smegmatis_MC2_155      ----------------MSRIGALALRDAVLDEG------SFRSWDTAPLD
TH_0091|M.thermoresistible__bu      ----------------MSRIGAVQFVETVLDTG------SFVSWDDPPLA
Mb0928c|M.bovis_AF2122/97           ----------------MSRITTDQLRHAVLDRG------SFVSWDSEPLA
Rv0904c|M.tuberculosis_H37Rv        ----------------MSRITTDQLRHAVLDRG------SFVSWDSEPLA
MMAR_4626|M.marinum_M               ----------------MSRITTDQLRDAVLDEG------SFISWDTPPLE
MUL_0237|M.ulcerans_Agy99           ----------------MSRITTDQLRDAVLDED------SFISWDTPPLE
MLBr_01657|M.leprae_Br4923          ----------------MTITAPKVVGKSIDPRD------PLLRLSN----
MAV_2190|M.avium_104                ----------------MTITAPETVGESLDPRD------PLLRLSN----
MAB_0181|M.abscessus_ATCC_1997      MPPHTTAEKLADLRERIALTREPGDAKAIARRDKKGIPSARARIDALLDK
                                                    ::        .::   .      .    .     

Mflv_1754|M.gilvum_PYR-GCK          VVTSAEYRAELAAAADATGLDESVVTGEGRVFGRRVALIACEFDFLAGSI
Mvan_4993|M.vanbaalenii_PYR-1       VPTSAEYRRELAEAEAATGLDESVLTGEGRVFGRRVALIACEFDFLAGSI
MSMEG_5642|M.smegmatis_MC2_155      VGADDEYRRELAEASAKTGLDESVLTGEGTVFGRRVAVVACEFDFLAGSI
TH_0091|M.thermoresistible__bu      IPADEDYRRELTDAAAVTGLDEAVLTGEGTIFGRRVALVACEFDFLAGSI
Mb0928c|M.bovis_AF2122/97           VPVADSYARELAAARAATGADESVQTGEGRVFGRRVAVVACEFDFLGGSI
Rv0904c|M.tuberculosis_H37Rv        VPVADSYARELAAARAATGADESVQTGEGRVFGRRVAVVACEFDFLGGSI
MMAR_4626|M.marinum_M               VPISESYARDLADARAATGRDESVLTGEGRVLGRRVAVVVCEFDFLAGSI
MUL_0237|M.ulcerans_Agy99           VPISESYARDLADVRAATGRDESVLTGEGRVLGRRVAVVACEFDFLAGSI
MLBr_01657|M.leprae_Br4923          --FFDDGRVEPLHERNQSG----VFAATGTVNGLRTIAFCTDGTVMGGAM
MAV_2190|M.avium_104                --FFDDGSVALLHERDRSG----VLAAAGTVNGVRTIAFCTDGTVMGGAM
MAB_0181|M.abscessus_ATCC_1997      GSFLELDAFARTPGDANAPYTDGVVTGLGRIDGRPVAVFSHDQTVYQGSV
                                                     :     * :. * : *  .  .  :  .  *::

Mflv_1754|M.gilvum_PYR-GCK          GVAAAERITAAVQRATAEGLPLLASPSSGGTRMQEGTVAFLQMVKIAAAV
Mvan_4993|M.vanbaalenii_PYR-1       GVAAAERIIAAVQKATAERLPLLASPSSGGTRMQEGTVAFLQMVKIAAAV
MSMEG_5642|M.smegmatis_MC2_155      GVAAAERITAAVQRATAERLPLLASPSSGGTRMQEGTVAFLQMVKIAAAV
TH_0091|M.thermoresistible__bu      GVAAAERIVAAVQRATAERLPLVASPSSGGTRMQEGTVAFLQMVKIAAAV
Mb0928c|M.bovis_AF2122/97           GVAAAERITAAVERATAERLPLLASPSSGGTRMQEGTVAFLQMVKIAAAI
Rv0904c|M.tuberculosis_H37Rv        GVAAAERITAAVERATAERLPLLASPSSGGTRMQEGTVAFLQMVKIAAAI
MMAR_4626|M.marinum_M               GVAAAERITAAVERATRQRLPLLASPSSGGTRMQEGTVAFLQMVKIAAAV
MUL_0237|M.ulcerans_Agy99           GVAAAERITAAMERATSQRLPLLASPSSGGTRMQEGTVAFLQMVKIAAAV
MLBr_01657|M.leprae_Br4923          GIEGCAHIVNAYDTAIEEQSPIVGIWHSGGARLAEG-VRALHAVGQVFEA
MAV_2190|M.avium_104                GIEGCSHIVDAYDTAIEEQSPIVGIWHSGGARLAEG-VKALHAVGLVFEA
MAB_0181|M.abscessus_ATCC_1997      GEMFGRKVAKLMEWAATNGCPVIGINDSAGARIQDTATSLAWYAELGRRH
                                    *     ::    : *  :  *::.   *.*:*: :  .     .      

Mflv_1754|M.gilvum_PYR-GCK          ELHKKGNLPYLVYLRHPTTGGVFASWG-SLGHVTAAEPD-ALIGFLGPRV
Mvan_4993|M.vanbaalenii_PYR-1       ELHKKAHLPYLVYLRHPTTGGVFASWG-SLGHVTAAEPG-ALIGFLGPRV
MSMEG_5642|M.smegmatis_MC2_155      ELHKQAHLPYLVYLRHPTTGGVFASWG-SLGHVTAAEPG-ALIGFLGPRV
TH_0091|M.thermoresistible__bu      QLHKLAHLSYLVYLRHPTTGGVFASWG-SLGHITIAEPN-ALIGFLGPRV
Mb0928c|M.bovis_AF2122/97           QLHNQARLPYLVYLRHPTTGGVFASWG-SLGHLTVAEPG-ALIGFLGPRV
Rv0904c|M.tuberculosis_H37Rv        QLHNQARLPYLVYLRHPTTGGVFASWG-SLGHLTVAEPG-ALIGFLGPRV
MMAR_4626|M.marinum_M               RLHKQAHLPYLVYLRHPTTGGVFASWG-SLGHVTVAEPG-ALIGFLGPRV
MUL_0237|M.ulcerans_Agy99           RLHKQAHLPYLVYLRHPTTGGVFASWG-SLGHVTVAEPG-ALIGFLGPRV
MLBr_01657|M.leprae_Br4923          MIRASGYIPQISVVVGFAAGG--AAYGPALTDVVIMAPE-GRVFVTGPDV
MAV_2190|M.avium_104                MIRASGYIPQISVVVGFAAGG--AAYGPALTDVVVMAPE-SRVFVTGPDV
MAB_0181|M.abscessus_ATCC_1997      ELLR-GTVPEISIILGKCAGG--AVYSPIQTDLLVAVRDQGYMFITGPDV
                                     :   . :. :  :    :**  * :.    .:       . : . ** *

Mflv_1754|M.gilvum_PYR-GCK          YEHLYGERFPSG-VQTSENLQRHGVIDAVVPLEVLRATVDRTLKVVADA-
Mvan_4993|M.vanbaalenii_PYR-1       YEHLYGEPFPAG-IQTAENLHRHGVVDAVIPPGILRATLDRALRVVSDA-
MSMEG_5642|M.smegmatis_MC2_155      YEHLYGEPFPSG-VQTAENLHAHGVIDGVVPLALLRETLDRTLRVVADP-
TH_0091|M.thermoresistible__bu      YQHLYGEPFPPG-VQTAENLHRHGVIDSVVPLPRLRSELDRALRVLVDE-
Mb0928c|M.bovis_AF2122/97           YELLYGDPFPSG-VQTAENLRRHGIIDGVVALDRLRPMLDRALTVLIDA-
Rv0904c|M.tuberculosis_H37Rv        YELLYGDPFPSG-VQTAENLRRHGIIDGVVALDRLRPMLDRALTVLIDA-
MMAR_4626|M.marinum_M               YELLYDEPFPAG-IQTAENLQRHGVIDGVVTLDELRRTLDRALTVLTDA-
MUL_0237|M.ulcerans_Agy99           YELLYDEPFPAG-VQTAENLQRHGVIDGVVTLDELRRTLDRALTVLTDA-
MLBr_01657|M.leprae_Br4923          VRSVTGEDVDMASLGGPETHHKKSGVCHIVANDELDAYERGRRLVGLFC-
MAV_2190|M.avium_104                VRSVTGEDVDMASLGGPETHHKKSGVCHIVADDELDAYERGRRLVGLFC-
MAB_0181|M.abscessus_ATCC_1997      IKDVTGEDVSFDELGGADVQAQRGNIHKVVEDEAAAFQYVRDYLSFLPSN
                                     . : .: .    :  .:    :. :  ::                    

Mflv_1754|M.gilvum_PYR-GCK          --PGPPPAAPEPE-VLPDIPAWDSVEISRRPDRPGVSFLLRHGATERVLL
Mvan_4993|M.vanbaalenii_PYR-1       --PDVPPAAPDAE-PLPDVPAWESVEISRRPDRPGVSALLRYGTTDRVLL
MSMEG_5642|M.smegmatis_MC2_155      --PGPAPAVIETE-DLPDVPAWDSVIASRRPDRPGVGFLLRHGATDQVLL
TH_0091|M.thermoresistible__bu      --PGTPPAPPDVDTSQPDVPAWDSVIASRRPDRPGVGYLLRHGATDTVLL
Mb0928c|M.bovis_AF2122/97           --PEPLPAPQTPA-PVPDVPTWDSVVASRRPDRPGVRQLLRHGATDRVLL
Rv0904c|M.tuberculosis_H37Rv        --PEPLPAPQTPA-PVPDVPTWDSVVASRRPDRPGVRQLLRHGATDRVLL
MMAR_4626|M.marinum_M               --PAPAPAAPAPT-AIPDVPAWTSVLASRRPDRPGVEHLLRYGATDRVLL
MUL_0237|M.ulcerans_Agy99           --PAPAPAAPAPP-AIPDVAAWTSVLASRRPDRPGVEHLLRYGATDRVLL
MLBr_01657|M.leprae_Br4923          --QQGHFDRSKAEAGDTNIQALLPESSRRAYD---VHPVVTAILDENTPF
MAV_2190|M.avium_104                --QQGHFDRTKAEAGDTDIHALLPESARRAYD---VRPIVTAILDDETPF
MAB_0181|M.abscessus_ATCC_1997      TFDYPPIVNPGLEPEITEDDLYLDTFIPDSDNQGYDMMEILLRIFDDGDI
                                                    .:             :       :     :   :

Mflv_1754|M.gilvum_PYR-GCK          SGTGQGESATMMLALARFGNQPAVVLGQQRVVGGL---VGPAALREARRG
Mvan_4993|M.vanbaalenii_PYR-1       SGTGQGEAATTLLALARFGGQPAVVLGQQRVVGGL---VGPAALREARRG
MSMEG_5642|M.smegmatis_MC2_155      SGTERGEAATTLLALARFGGQPAVVLGQRRIVGGL---VGPGALREARRG
TH_0091|M.thermoresistible__bu      SGSGGGEAATTLLALARFGGQPAVVLGQQRVIGAM---VGPAALREARRG
Mb0928c|M.bovis_AF2122/97           SGTDQGEAATTLLALARFGGQPTVVLGQQRAVGGGGSTVGPAALREARRG
Rv0904c|M.tuberculosis_H37Rv        SGTDQGEAATTLLALARFGGQPTVVLGQQRAVGGGGSTVGPAALREARRG
MMAR_4626|M.marinum_M               SGTGYGDAATTLLALARMAGQPMVVLGQQ-GIGGG--IIGPASLREARRG
MUL_0237|M.ulcerans_Agy99           SGTGYGDAATTLLALARMAGQPMVVLGQQ-GIGGG--IIGPASLREARRG
MLBr_01657|M.leprae_Br4923          DEFQANWAPSMVVGLGRLSGRTVGVLANNPLRLGG--CLNSESAEKAARF
MAV_2190|M.avium_104                DEFQANWAPSMVIGLGRLSGRTVGVLANNPLRLGG--CLNSESAEKAARF
MAB_0181|M.abscessus_ATCC_1997      FEISEQRGPAMITAFARVDGHPVGVIANQPLQMAG--AVDTDASDKAASF
                                           ..: : .:.*. .:.  *:.:.    .    :.. :  :*   

Mflv_1754|M.gilvum_PYR-GCK          MALAASLKLPLVLVIDTAGPALSTEAEEGGLAGEIARCLAELVTLDTPTV
Mvan_4993|M.vanbaalenii_PYR-1       MALAAGLKLPLVLVIDTAGPALSTEAEEGGLAGEIARCLAELVTLDTPTV
MSMEG_5642|M.smegmatis_MC2_155      MALAAGLQLPLVLVIDTAGPALSTEAEQGGLAGEIARCLAELVTLDTPTV
TH_0091|M.thermoresistible__bu      MALAADLQLPLVLVIDTAGPALTAEAEQGGLASEIAHCLAELVTLDTATL
Mb0928c|M.bovis_AF2122/97           MALAAELCLPLVLVIDAAGPALSAAAEQGGLAGQIAHCLAELVTLDTPTV
Rv0904c|M.tuberculosis_H37Rv        MALAAELCLPLVLVIDAAGPALSAAAEQGGLAGQIAHCLAELVTLDTPTV
MMAR_4626|M.marinum_M               MALAAELRLPLVLVIDTAGPALSADAEQGGLAGQIAQCLAELVTLGTPTV
MUL_0237|M.ulcerans_Agy99           MALAAELRLPLVLVIDTAGPALSADAEQGGLAGQIAQCLAELVTLGTPTV
MLBr_01657|M.leprae_Br4923          VRLCDAFGIPLVVIVDVPGYLPGVDQEWGGVVRRGAKLLHAFGECTVPRV
MAV_2190|M.avium_104                VRLCDAFGIPLVVIVDVPGYLPGVDQEWGGVVRRGAKLLHAFGEATVPRV
MAB_0181|M.abscessus_ATCC_1997      IRFCDAYNLPLVFVVDTPGALPGVSEEKNGIIKKGGRFFNAVVEADVPKV
                                    : :.    :***.::*..*    .  * .*:  . .: :  .    .. :

Mflv_1754|M.gilvum_PYR-GCK          SVLLGQGSGGPALAMVPADRVLAALHGWLAPLPPEGASAIVFRDVDHAPE
Mvan_4993|M.vanbaalenii_PYR-1       SVLLGQGSGGPALAMVPADRVLAALHGWLAPLPPEGASAIVFRDVDHAPE
MSMEG_5642|M.smegmatis_MC2_155      SVLMGQGSGGPALAMVPADRVLAASNGWLAPLPPEGASAIVYRDTEHAPE
TH_0091|M.thermoresistible__bu      SVLLGQGSGGPALAMVPADRVLAARHGWLAPLPPEGVSAIVHRDLDHAPE
Mb0928c|M.bovis_AF2122/97           SILLGQGSGGPALAMLPADRVLAALHGWLAPLPPEGASAIVFRDTAHAAE
Rv0904c|M.tuberculosis_H37Rv        SILLGQGSGGPALAMLPADRVLAALHGWLAPLPPEGASAIVFRDTAHAAE
MMAR_4626|M.marinum_M               SVLLGQGSGGPALAMVPADRVLAAQHGWLAPLPPEGASAIVFRDTTHAAE
MUL_0237|M.ulcerans_Agy99           SVLLGQGSGGPALAMVPADRVLAAQHGWLAPLPPEGASAIVFRDTTHAAE
MLBr_01657|M.leprae_Br4923          TLVTRKTYGGAYIAMNSRSLNATKVFAWPD------AEVAVMGAKAAVGI
MAV_2190|M.avium_104                TLVTRKTYGGAYIAMNSRSLNATKVFAWPD------AEVAVMGAKAAVGI
MAB_0181|M.abscessus_ATCC_1997      TIITRKAYGGGYAVMGSKQLSADLNYVWPT------ARIAVIGAEGAAQL
                                    :::  :  **   .* . .        *        .   *      .  

Mflv_1754|M.gilvum_PYR-GCK          LAAAQGIRSVDLLRDGIVDAVVPEHPDAAD--EPRAFVERLSATIAVELH
Mvan_4993|M.vanbaalenii_PYR-1       LAAAQGIRSADLLRNGIVDAIVPEHPDAAD--EPQAFTQRLSATIAVELH
MSMEG_5642|M.smegmatis_MC2_155      LAAAQGVRAVDLLRHGIVDVVVAEKPDAAD--EPRAFTARLSTAIAAELH
TH_0091|M.thermoresistible__bu      LAARQGIRSVDLLRHGIVDAIVDERPDAAD--EPMEFTARLADSIAVELH
Mb0928c|M.bovis_AF2122/97           LAAAQGIRSADLLKSGIVDTIVPEYPDAAD--EPIEFALRLSNAIAAEVH
Rv0904c|M.tuberculosis_H37Rv        LAAAQGIRSADLLKSGIVDTIVPEYPDAAD--EPIEFALRLSNAIAAEVH
MMAR_4626|M.marinum_M               LAAAQGIRSADLLAAGIVDVIVPELPDAAA--EPVEFAQRLSIAIATEVA
MUL_0237|M.ulcerans_Agy99           LAAAQGIRSADLLAAGIVDVIVPELPDAAA--EPVEFAQRLSIAIATEVA
MLBr_01657|M.leprae_Br4923          LHKRKLAAAPNDEREALHDDLAAEHERIAGGVDSAIDIGVVDEKINPAHT
MAV_2190|M.avium_104                LHKKKLAAAPEHEREALHDQLAAEHEKIAGGVDSAIEIGVVDEKIDPAHT
MAB_0181|M.abscessus_ATCC_1997      LVKRFPDPTAPEVQKIRADFIEGYNKNLATP-WIAAERGYIDGVIEPHQT
                                    *       :         * :       *           :   *     

Mflv_1754|M.gilvum_PYR-GCK          RLRFAPEAERSASRLERYRRIGLA-----
Mvan_4993|M.vanbaalenii_PYR-1       RLRTVPDEQRLAARLERYRRIGLP-----
MSMEG_5642|M.smegmatis_MC2_155      NLRAVPDDERLQTRLQRYRRIGL------
TH_0091|M.thermoresistible__bu      RLREMPAESRLETRLARYRRIGLPR----
Mb0928c|M.bovis_AF2122/97           ALRKIPAPERLATRLQRYRRIGLPRD---
Rv0904c|M.tuberculosis_H37Rv        ALRKIPAPERLATRLQRYRRIGLPRD---
MMAR_4626|M.marinum_M               ALREIPDAQRMTARLARYRSIGLPRDR--
MUL_0237|M.ulcerans_Agy99           ALREIPDAQRMTARLARYRSIGLPRDR--
MLBr_01657|M.leprae_Br4923          RSKLTEALAQSPVRRGRHKNIPL------
MAV_2190|M.avium_104                RSKLTEALAQAPARRGRHKNIPL------
MAB_0181|M.abscessus_ATCC_1997      RLLLRKSLKLLRDKQKHDRMQRKHGLTPI
                                                 :  : :